| Entries |
| Document | Title | Date |
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| 20080208114 | NEEDLE-FREE INJECTION DEVICES AND DRUG DELIVERY SYSTEMS THEREFOR - Needle-free injection devices and drug delivery systems are disclosed. The needle-free injection devices may include a drug delivery system, a power source, an activation system, and a disabling element. The drug delivery system may include a needle-free syringe and a drug storage system. The needle-free syringe may include a plunger slidably disposed within an injection chamber. The injection chamber may include an injection orifice, and the plunger may be configured to expel a volume of fluid from the injection chamber through the injection orifice. The drug storage system may include a storage chamber and an outlet. The drug storage system may be frangibly connected to the needle-free syringe with the outlet proximate to and fluidly connected with the injection orifice. The drug storage system may be configured to inject a fluid from the storage chamber through the outlet, through the injection orifice, and into the injection chamber. | 08-28-2008 |
| 20080214995 | VISCOUS FORMULATIONS AND THEIR USE IN NEEDLE-FREE INJECTION - Formulations are described that are viscous and will benefit from needle-free delivery at high driving pressures. Conventional delivery of these viscous formulations by hypodermic syringes is inconvenient as well as painful. Formulations include those which have a viscosity of about 5 cS or more at about 20° C. and which can have 0.5 ml or more administered by a needle-free injector in about 0.1 second±0.02 seconds. | 09-04-2008 |
| 20080214996 | NEEDLELESS INJECTORS - A needleless injector generally includes a barrel having a proximal and a distal end and a bore therethrough along with an injection head disposed at the barrel distal end in fluid communication with the bore; an energy source is disposed at the barrel proximal end and a bolt may be disposed in said bore for reciprocating movement therein, from a first position to a second position for drawing medicament into the bore, the bolt being fitted in the bore in order to force medicament through the injection head upon movement of the bolt from the second to the first position. A mechanism is provided for activating the energy source in order to operate the bolt. | 09-04-2008 |
| 20080281261 | Needle-less injector - A needle-less injector device that includes an outer housing and an inner housing that is slideably supported from the outer housing is disclosed. The inner housing supporting a vial that includes a nozzle for delivering a fluid held within the vial. A spring powered ram that is adapted for pushing a seal and plunger is mounted within inner housing. A skin tensioning spring mounted between the inner housing and the outer housing is used for pushing the leading end of the inner housing away from the outer housing. A trigger that cooperates with the spring-powered ram is used to release the ram from the cocked position only when the inner housing is in a firing position. | 11-13-2008 |
| 20090030367 | SOFT TISSUE AUGMENTATION BY NEEDLE-FREE INJECTION - The invention relates to needle-free apparatus that can be used to augment soft tissue. More specifically, the needle-free injectors of the present invention allow injection of more viscous materials such as collagen, hyaluronic acid, and other polymers that are useful as dermal fillers. The needle-free injectors of the present invention allow injection of such materials to fill the undesired lines, wrinkles, and folds of a patient. The present invention also relates to kits comprising such needle-free injectors and a quantity of dermal filling material. In addition, the present invention relates to methods of augmenting soft tissue using needle-free apparatus. | 01-29-2009 |
| 20090124966 | AMPOULE USABLE AS A SYRINGE AND A SYRINGE UNIT COMPRISING THE AMPOULE - The object is to provide an ampoule usable as a syringe, and a syringe unit which are easy to handle, excellent in quantitative accuracy, and further more excellent in hygienic aspect. | 05-14-2009 |
| 20090137948 | NEEDLE-FREE INJECTION DEVICE WITH AUTO-DISABLE - Needle-free injection devices having a body, an actuation system, and a delivery system including a drive assembly and configured to receive a nozzle assembly. In some embodiments, the drive assembly includes a spring and a support member configured to restrict movement of the spring in a direction non-parallel to a central axis of the spring. In some embodiments, the drive assembly includes a transmission assembly configured to couple a drive source with the actuation system upon engagement of a nozzle assembly with the drive assembly. In some embodiments, the body is configured to acoustically seal an interface between the delivery system and the actuation system. In some embodiments, the body includes a gripping member selectively extendable from the body. | 05-28-2009 |
| 20090156992 | NEEDLE-FREE INJECTION DEVICE AND PRIMING SYSTEM - Needle-free injection devices having a delivery system to effect an injection and a body configured to house the delivery system. The delivery system includes an injectate assembly adapted to house a volume of liquid and a drive assembly adapted to expel the volume of liquid from the injectate assembly. In some embodiments, the drive assembly includes a pair of parallel springs. The device further includes a priming system adapted to prepare the device for delivery of an injection. The priming system includes a force-preparation assembly adapted to selectively arrange the drive assembly to provide the drive force to the injectate assembly. In some embodiments, the priming system includes a locking assembly adapted to releasably retain the injectate assembly relative to the body. In some embodiments, the priming system includes a dosing assembly adapted to selectively draw a volume of liquid into the injectate assembly. | 06-18-2009 |
| 20090254026 | Syringe Device Comprising a Motor Adapted for Filling an Injection Chamber - The present application relates to a syringe device comprising an injector chamber and a medicament container each comprising a piston. In particular the present application relates to a device comprising motor arranged to move an injector piston and/or a reservoir piston so as to transfer a medicament in the medicament container to the injector chamber. Furthermore, the present application relates to a syringe device comprising a motor arranged to strain the spring for assisting the ejection action. Moreover, the present application relates to the use of a motor to strain a spring of a syringe device. | 10-08-2009 |
| 20090299278 | INJECTOR WITH ADJUSTABLE DOSING - An injector for injecting medicament in a patient. The injector includes a container comprising a fluid chamber containing a first volume of a medicament, and an injection conduit associated with the fluid chamber for defining a fluid pathway therefrom to inject the medicament from the fluid chamber through the injection conduit to an injection location. The injector also includes a firing mechanism associated with the fluid chamber for expelling the medicament from the fluid chamber through the injection conduit, and a volume-control mechanism operable to control a fraction of the first volume of medicament that is injected when the firing mechanism is actuated to inject the medicament. | 12-03-2009 |
| 20090318859 | System for injection through or into the human skin - The invention relates to a system for injecting a fluid through or into the human skin, optionally by needle-free injection or by injection with a needle, with
| 12-24-2009 |
| 20090318860 | End Portion Of Hermetically Sealed Container Having Fine Opening Surface Obtained Easily by Cleavage - An easy-to-open end portion of a hermetically sealed container contains a substantially flat opening surface. The opening surface is free of broken pieces when the end portion is opened. The container comprises a tip portion, a truncated conical coupling portion for coupling the tip portion and a body portion, and a joint portion, wherein the tip portion, the joint portion, the coupling portion, and the body portion are arranged coaxially to have a central axis, and space portions are provided to extend continuously from the body portion to the middle of the joint portion. The joint portion can be broken by applying a force from the lateral direction of the central axis on the tip portion. As a result, the head portion of the truncated conical portion is exposed and the space portion of the coupling portion becomes a free end. | 12-24-2009 |
| 20100063439 | INJECTION DEVICE - The invention relates to an injection device, especially for a device for injecting an injectable product. Said device comprises a reservoir ( | 03-11-2010 |
| 20100076373 | Disposable injector with at least one support rod - A disposable injector with a housing ( | 03-25-2010 |
| 20100076374 | INJECTION DEVICE PLUNGER AUTO-DISABLE - A nozzle assembly for a needle-free injection device. The nozzle assembly includes a nozzle body including an injectate chamber and one or more outlet orifices and a plunger configured to move through the injectate chamber toward the one or more outlet orifices. In some embodiments, the plunger includes a first portion and a second portion removably joined by a frangible region. In some embodiments, the plunger includes extensions configured to couple the plunger to a drive assembly of a needle-free injection device. | 03-25-2010 |
| 20100094205 | Dosing and Drive Mechanism for Drug Delivery Device - The present invention relates to drive mechanisms suitable for use in drug delivery devices, in particular pen-type injectors, wherein a number of pre-set doses of medicinal product can be administered. In particular, the present invention relates to such drug delivery devices where a user may activate the drug delivery device. | 04-15-2010 |
| 20100094206 | Drive mechanisms suitable for use in drug delivery devices - The present invention relates to drive mechanisms suitable for use in drug delivery devices, in particular pen-type injectors, wherein a number of pre-set doses of medicinal product can be administered. In particular, the present invention relates to such drug delivery devices where a user may activate the drug delivery device. | 04-15-2010 |
| 20100094207 | Drive mechanisms suitable for use in drug delivery devices - The present invention relates to drive mechanisms suitable for use in drug delivery devices, in particular pen-type injectors, wherein a number of pre-set doses of medicinal product can be administered. In particular, the present invention relates to such drug delivery devices where a user may activate the drug delivery device. | 04-15-2010 |
| 20100106084 | Disposable injector with at least one drawer hook which can be forcibly decoupled - A disposable injector with a housing ( | 04-29-2010 |
| 20100137791 | DRIVE ASSEMBLY SUITABLE FOR USE IN A MEDICATION DELIVERY DEVICE AN MEDICATION DELIVERY DEVICE - A drive assembly for use in a medication delivery device is provided for, which comprises a housing having a proximal end and a distal end, a drive member moveable in the proximal direction with respect to the housing for setting a dose of the medication to be delivered and in the distal direction with respect to the housing for delivering the dose, a piston rod adapted to be driven by the drive member in the distal direction with respect to the housing during movement of the drive member in the distal direction for delivering the dose and a restriction member for restricting proximal movement of the piston rod with respect to the housing during proximal movement of the drive member by mechanical interaction of the restriction member with a stop feature of the piston rod, wherein the restriction member and the stop feature are arranged for the piston rod to be moved proximally a first distance during a first proximal movement of the drive member before the restriction member and the stop feature interact mechanically, wherein the first distance which the piston rod moves proximally during the first proximal movement of the drive member is larger than a subsequent distance which the piston rod moves proximally during a subsequent proximal movement of the drive member. | 06-03-2010 |
| 20100137792 | MEDICATION DELIVERY DEVICE AND METHOD FOR OPERATING A MEDICATION DELIVERY DEVICE - A medication delivery device ( | 06-03-2010 |
| 20100168662 | NEEDLE-LESS INJECTOR AND METHOD OF FLUID DELIVERY - A needle-less injector device for delivering a dose of fluid intradermally, subcutaneously or intramuscularly to an animal or human. The device includes an inner housing having opposed ends. A syringe is disposed in one end of the inner housing. The syringe includes a nozzle for delivering a dose of fluid held within the syringe. A plunger is movably disposed within the syringe. A spring powered hammer is movably disposed within the inner housing. The hammer cooperates with the plunger to drive the dose of medicament from the nozzle. An injection delivery spring for powering the hammer is positioned and compressed between the other end of the inner housing and the spring powered hammer. An outer housing slideably supports the inner housing. A skin tensioning spring is mounted between the inner housing and the outer housing, the skin tensioning spring biasing the nozzle of the syringe against the animal or human. A trigger mechanism is disposed in the outer housing, the trigger mechanism cooperating with the spring powered hammer to release the injection delivery spring, wherein the size of the injection delivery spring and the length of the hammer dictate the amount of dose delivered and whether the dose is delivered intradermally, subcutaneously or intramuscularly to an animal or human. | 07-01-2010 |
| 20100234798 | NEEDLELESS INJECTION STRUCTURE - A needleless injection structure includes a duct, a stuff base and a casing. The duct has a through channel. The duct has a ring channel and a transverse channel formed on a top thereof. The stuff base is disposed on the top of the duct. The stuff base has an uneven portion, a first fillet, a plurality of first protrusions and a closed space. The casing is assembled on the duct. The casing has an opening, a second fillet, an accommodating space and a plurality of second protrusions. The opening communicates with the accommodating space. The stuff base stays in the accommodating space. The improved needleless injection structure is provided thereby, which results in increasing the use of safety, saving the cost, and mitigating the pain of the patient. | 09-16-2010 |
| 20100241066 | Mechanism for Injection Device - A pressurised injection device comprises a mechanical loading mechanism comprising a double set of rackets ( | 09-23-2010 |
| 20100249697 | Disposable injector with dual-piston dual-chamber system - The invention relates to a disposable injector with a housing, an injector-side, first cylinder-piston unit—at least intermittently fillable—arranged thereon and an upstream detachable container adapter, wherein the container adapter bears a likewise at least intermittently fillable second cylinder-piston unit. A solvent is stored in the first cylinder-piston unit. In the second cylinder-piston unit there is a freeze-dried active pharmaceutical ingredient. Immediately before use of the disposable injector the solvent is conveyed to the second cylinder-piston unit to the active pharmaceutical ingredient, where a solution forms. This solution is transfer-pumped into the first cylinder-piston unit to then be administered. | 09-30-2010 |
| 20100274183 | DEVICE FOR READYING A NEEDLE FREE INJECTOR FOR DELIVERY - A needle-free injector device comprising a latch having a safe position which disables the triggering of the device, and a ready position which restrains movement of a dispensing member but enables triggering and a triggered position which permits movement of the dispensing member is disclosed. An additional safety mechanism blocks the triggering of the device until removed. A cap is provided to maintain the sterility and stability of the drug formulation and is configured such that the cap removal is required prior to placing the device in a ready to trigger state. | 10-28-2010 |
| 20100286603 | KIT AND METHOD FOR PREPARATION OF A DEGARELIX SOLUTION - A kit and method for preparing a Degarelix solution for administration to a patient. The kit includes a first chamber containing lyophilised Degarelix, a second chamber containing water, a syringe for transferring the water from the first chamber to the second chamber, at least one of a hypodermic needle, a safety needle device, or a needleless device for delivery of the Degarelix to the patient, and a mixing apparatus. The mixing apparatus is configured to receive the first chamber to mix the Degarelix and water to produce a Degarelix solution suitable for deliver to a patient. The method includes transferring a volume of water from a first chamber into a second chamber containing lyophilised Degarelix, connecting the second chamber to a mixing apparatus and mixing the water and lyophilised Degarelix for a period of time. | 11-11-2010 |
| 20100286604 | Universal Syringe with Retractable Needle - This invention relates to medical devices useful for infusion therapy and, more particularly, to a syringe that can be selectively used with a retractable needle or with frontal attachment devices such as luer hubs, valves or other connectors in needleless systems. | 11-11-2010 |
| 20110009815 | INJECTION DEVICE FOR THE NEEDLE-FREE INJECTION OF A MEDIUM - The invention relates to an injection device consisting of an injector and an ampoule unit for the needle-free injection of a medium. | 01-13-2011 |
| 20110015566 | NEEDLE-LESS SYRINGE ADAPTER - A needle-less syringe adapter has a tube, a resilient valve, a piercing member and an injection member. The tube has a body has a cavity and an outlet hole. The resilient valve is mounted in the cavity and has a chamber, a top slit and a bottom slit. The piercing conduit is mounted in the chamber, is driven to move when the resilient valve is compressed, selectively extends out through the top and bottom slits and has a through hole defined through the piercing conduit. The injection member is mounted on the tube and is selectively sealed by the resilient valve. The needle-less syringe adapter has excellent hermetical characteristics to prevent air infiltration and backflow of bloody and liquid medicine in a patient's blood vessel. | 01-20-2011 |
| 20110034868 | SYSTEM FOR INJECTING A FLUID THROUGH OR INTO HUMAN SKIN - The invention relates to a system for injecting a fluid through or into human skin, optionally by needle-free injection or by injection with a needle, comprising
| 02-10-2011 |
| 20110066104 | DEVICE FOR NEEDLELESS TRANSDERMAL DELIVERY OF MEDICATION - The invention relates to a device for needleless transdermal drug delivery. The device according to the invention comprises an actuator ( | 03-17-2011 |
| 20110092898 | MEDICINE INJECTION INTO SKIN WITH HEATER CHIP - A device configured for drug delivery through the skin of a subject, the device comprising a substrate, a proximal side of which is positioned toward the skin of the subject during use; at least one fluid receptacle positioned on the substrate and containing a store of the drug; at least one ejection chamber positioned on the proximal side of the substrate; at least one fluid via fluidly connecting the at least one fluid receptacle with the at least one ejection chamber; a heating element positioned adjacent at least a portion of the at least one ejection chamber, said heating element configured to rapidly heat and vaporize the fluid along that portion of the ejection chamber, causing ejection of fluid therefrom; and logic, wherein the logic is programmable to initiate heating by the heating element. | 04-21-2011 |
| 20110112473 | MEDICATION INJECTION SITE AND DATA COLLECTION SYSTEM - A medication injection site is provided that includes a medication port and an identification sensor. The medication injection site, when coupled to a medication container, can wirelessly transmit data characterizing the contents of the medication container to a remote data collection system. The housing of the medication injection site has a shape and size enabling it to be held by a first hand of a user while the user administers medication from the medication container via the medication port using his or her second hand. In some implementations, the medication injection site can be placed on an IV drip line. Related apparatus, systems, and kits are also disclosed. | 05-12-2011 |
| 20110112474 | MEDICATION INJECTION SITE AND DATA COLLECTION SYSTEM - A medication delivery apparatus for use with a medication container includes a housing, a fluid conduit at least partially extending within the housing and configured to deliver medication within the medication container to a patient, a medication port extending from the housing and configured to be coupled to a fluid outlet of the medication container, the medication port being fluidically coupled to the fluid conduit, and at least one sensor disposed within the housing to generate information characterizing administration of the medication for processing by a remote data collection system. The housing can have a size and shape that enables it to be supported by a first hand of a user while the user administers the medication from the medication container via the medication port using a second hand of the user. Related apparatus, systems, and techniques are also described. | 05-12-2011 |
| 20110118663 | CASING - A casing for an injection device of the type having a safety device which prevents operation of the device, incorporating an actuator means by which the safety means of the device can be actuated to allow operation of the device. Also a casing for a medicament container having an opening closed prior to use by a break-off tip, having relatively moveable first and second casing parts, which on relative movement apply a breaking force to the break-off tip. A preferred embodiment includes both such features. | 05-19-2011 |
| 20110130717 | SYRINGE WITH UNIVERSAL END-PIECE - The present invention relates to a syringe ( | 06-02-2011 |
| 20110208119 | Disposable injector provided with high injector safety - The invention relates to a needle-less, disposable injector comprising a housing ( | 08-25-2011 |
| 20110238006 | NEEDLELESS INJECTION DEVICE COMPONENTS, SYSTEMS, AND METHODS - Described are needleless injection systems ( | 09-29-2011 |
| 20110245761 | Injection device - An injection device ( | 10-06-2011 |
| 20110245762 | DEVICES, SYSTEMS AND METHODS FOR DELIVERING FLUID TO TISSUE - An injection system ( | 10-06-2011 |
| 20110251550 | Single-use injector having a flexurally elastic metal housing - A single-use injector comprising a housing ( | 10-13-2011 |
| 20110251551 | Single-use injector capable of pumping and having a flexurally elastic housing - A single-use injector comprising a housing ( | 10-13-2011 |
| 20110264036 | DEVICES, SYSTEMS AND METHODS FOR DELIVERING FLUID TO TISSUE - In one aspect of this invention, control systems ( | 10-27-2011 |
| 20110270161 | Injection Device - An injection device ( | 11-03-2011 |
| 20120041364 | INTERLOCK MECHANISM FOR A DRUG DELIVERY DEVICE AND DRUG DELIVERY DEVICE - The invention refers to an interlock mechanism for restricting a rotational movement of a rotatable component ( | 02-16-2012 |
| 20120059314 | ATTACHMENT FOR A STANDARD SYRINGE AND INJECTION DEVICE FOR NEEDLE-FREE INJECTION - The invention relates to an attachment ( | 03-08-2012 |
| 20120059315 | NEEDLELESS INJECTOR ACCESSORIES - A disposable nozzle for use on the discharge end of the barrel of a needleless injector is threaded onto the front end of a holder mounted in the barrel. A resilient detent extending outwardly at an acute angle from the inner wall of a recess in the rear end of the nozzle repeatedly enters and exits notches in a sleeve on the holder when the nozzle is mounted on the holder providing an audible signal that the nozzle has not been used. Reverse rotation of the nozzle during removal from the holder results in breaking of the detent. Thus, mounting of a used nozzle on the holder would not be accompanied by a signal that the nozzle is unused. | 03-08-2012 |
| 20120101431 | CYLINDER-PISTON UNIT SUITABLE FOR STORING INJECTION SOLUTIONS FOR A NEEDLE-FREE AUTOMATIC OR MANUAL FILLING OF THE CYLINDER-PISTON UNIT, ALSO UNDER ATMOSPHERIC PRESSURE - A pressure-stable cylinder/piston unit which blocks water vapor and oxygen and is designed for a needle-free injector, with a chamber arranged in a cylinder, which blocks water vapor and oxygen, and designed for long-term and sterile storage of an injection solution, an end wall with at least one nozzle bore or one outlet element, a pressure-stable outer cylinder, and a pressure-stable piston arranged movably in the chamber and blocking water vapor and oxygen. Methods for bubble-free, automatic or manual filling of the cylinder/piston unit, also at atmospheric pressure are also disclosed. | 04-26-2012 |
| 20120109049 | NEEDLELESS INJECTION DEVICE COMPONENTS, SYSTEMS, AND METHODS - A needleless fluid injection system include a working shaft ( | 05-03-2012 |
| 20120157914 | Devices, Assemblies and Methods for Controlling Fluid Flow - A valve is provided for controlling flow along a fluid line that includes an outer shell and an inner housing slidably disposed therein that includes connector threads surrounding a boss on one end and a passage through the boss. A backing member is coupled to the outer shell and has a sealing pin extending into the passage. A connector may be threaded into the one end of the inner housing, thereby slidably engaging the connector threads, causing the inner housing to move helically from a closed position wherein the sealing pin engages an outlet opening at the distal end of the boss to seal the outlet opening and an open position wherein the inner housing is directed away from the sealing pin to open a fluid path through the valve, around the pin, and through the outlet opening. | 06-21-2012 |
| 20120179094 | MEDICAMENT CONTAINER - The invention relates to a medicament container, comprising a cavity at least partially defined by a container wall comprising a soft, flexible inner layer consisting of a soft material and a rigid outer layer consisting of a rigid material, wherein the layers are arranged as a one-piece part by two component injection moulding. | 07-12-2012 |
| 20120197186 | DISPOSABLE INJECTOR COMPRISING AT LEAST ONE DRAW HOOK AND A SLIDING WEDGE-TYPE GEAR FOR UNLOCKING A LOCKING ELEMENT - A disposable injector with a housing ( | 08-02-2012 |
| 20120253272 | NEEDLELESS INJECTOR - A pistol-shaped needleless injector includes a readily replaceable barrel ( | 10-04-2012 |
| 20120253273 | NEEDLELESS INJECTOR DRUG CAPSULE AND A METHOD FOR FILLING THEREOF - A method for tilling needleless injector capsules with liquid drug, whereby dissolved gas within the drug is replaced by a less soluble gas in order to reduce the inclusion of gas bubbles, or to prevent the growth of bubbles during storage and thereby prevent breakage of the capsules. | 10-04-2012 |
| 20120296270 | VISCOUS FORMULATIONS AND THEIR USE IN NEEDLE-FREE INJECTION - Formulations are described that are viscous and will benefit from needle-free delivery at high driving pressures. Conventional delivery of these viscous formulations by hypodermic syringes is inconvenient as well as painful. Formulations include those which have a viscosity of about 5 cS or more at about 20° C. and which can have 0.5 ml or more administered by a needle-free injector in about 0.1 second±0.02 seconds. | 11-22-2012 |
| 20120302947 | ELECTRICAL NEEDLE-FREE INJECTOR SYSTEM - In one aspect of the invention, a system comprising a needle-free injector is disclosed. The system comprises a needle-free injector comprising a trigger assembly adapted to exert an injection force, the trigger assembly comprising a spring storing the injection force. The system also comprises a winding mechanism for priming the spring for the storing of the injection force, wherein the winding mechanism is electrically powered. According to another aspect of the present invention, an alternate needle-free injector system is disclosed. The system comprises a needle-free injector comprising a nozzle adapted to be loaded with an injectable. The system also comprises a dosing mechanism for loading the injectable into the nozzle, wherein the dosing mechanism is electrically powered. | 11-29-2012 |
| 20120323171 | DEVICE FOR READYING A NEEDLE FREE INJECTOR FOR DELIVERY - A needle-free injector device comprising a latch having a safe position which disables the triggering of the device, and a ready position which restrains movement of a dispensing member but enables triggering and a triggered position which permits movement of the dispensing member is disclosed. An additional safety mechanism blocks the triggering of the device until removed. A cap is provided to maintain the sterility and stability of the drug formulation and is configured such that the cap removal is required prior to placing the device in a ready to trigger state. | 12-20-2012 |
| 20130035634 | Needle-Free Injection Device - A needle-free injection device having an outer housing and an inner housing is disclosed. The inner housing is configured to receive a needle-free syringe in one end. In addition, the inner housing is movable within the outer housing between a syringe loading position and a firing position. The device also includes an activation button operatively associated with the inner and outer housings and a housing lock engaged by the activation button to prohibit movement of the inner housing from the syringe loading position to the firing position when the activation button is activated with the inner housing in the syringe loading position. Methods and apparatus for using, filing and operating the needle-free injection device are also disclosed. | 02-07-2013 |
| 20130046233 | NEEDLELESS INJECTOR - A needleless injector has a syringe body having an opening at one end, a piston housed within the syringe body for urging a liquid within the syringe body through the opening and a ram for driving the piston. A shock absorbing component is provided for reducing an initial transfer of force from the ram to the piston. The initial rate of pressure increase on the liquid is reduced, thereby controlling the rate of collapse of gas bubbles in the liquid. | 02-21-2013 |
| 20130072865 | CASING - A casing for an injection device of the type having a safety device which prevents operation of the device, incorporating an actuator means by which the safety means of the device can be actuated to allow operation of the device. Also a casing for a medicament container having an opening closed prior to use by a break-off tip, having relatively movable first and second casing parts, which on relative movement apply a breaking force to the break-off tip. A preferred embodiment includes both such features. | 03-21-2013 |
| 20130158474 | Intranasal Cartridge Devices - Intranasal delivery devices include dosage forms containing medical compositions for use in the intranasal devices, and methods of delivering medical compositions to the nasal mucosa of users. The devices dispense a predetermined quantity of fluid into the nasal passage of a user, in which the predetermined quantity of fluid is contained in, or produced in a dosage form or blister that is crushed by a plunger with sufficient force to drive the dosage form against a piercing mechanism, piercing the dosage form and forcing the liquid contents from the dosage form and through a delivery channel into a spray to be directed into the nasal passage of a user. The plunger is connected to a trigger device by a linkage that confers a mechanical advantage to the trigger mechanism. | 06-20-2013 |
| 20130165851 | TUBE WITH A FEMALE LUER LOCK FITTING - The disclosure relates to tube with a tube head ( | 06-27-2013 |
| 20130190684 | PISTON FOR A NEEDLELESS VALVE SYSTEM - A piston for a needleless valve system comprising a head portion configured to be disposed in the needleless valve system and controlling fluid flow through the needleless valve system. The head portion comprising a continuous top surface, and an opening disposed proximate the continuous top surface, wherein the continuous top surface is non-planar when the opening is in an open position. | 07-25-2013 |
| 20130190685 | NEEDLELESS INJECTOR - The present invention relates to a needleless injector. The needleless injector includes: a piston shaft including a plurality of holders on an outer surface in a circumferential direction thereof; a cylinder assembly which slidably receives and supports the piston shaft in the forward and backward directions; a plurality of balls which are received in the cylinder assembly and disposed around the piston shaft, the plurality of balls being movable in a radial direction and inserted into the plurality of holders when the piston shaft is moved in the backward direction; a trigger button slidably coupled to a rear end of the cylinder assembly to form a trigger end interrupting the movement of the balls inserted into the holders in the radial direction, the trigger button releasing the interruption of the trigger end when the piston shaft is slid in the forward direction; a first elastic pressing unit for pressing the piston in the forward direction; and a second elastic pressing unit for pressing the trigger button in the backward direction. | 07-25-2013 |
| 20130204183 | DRUG DELIVERY DEVICE AND METHOD FOR ASSEMBLING A DRUG DELIVERY DEVICE - A drug delivery device comprises a first component and a second component, wherein a substance is provided on at least one of the first component and the second component. An inner friction of the substance is great enough to stabilize at least one of the orientation and the position of the first component and the second component with respect to one another. The inner friction of the substance is small enough to allow relative movement of the first component and the second component necessary for the intended operation of the device. Furthermore, a method for assembling a drug delivery device is provided. | 08-08-2013 |
| 20130338578 | NEEDLELESS INJECTOR DRUG CAPSULE AND A METHOD FOR FILLING THEREOF - A method for tilling needleless injector capsules with liquid drug, whereby dissolved gas within the drug is replaced by a less soluble gas in order to reduce the inclusion of gas bubbles, or to prevent the growth of bubbles during storage and thereby prevent breakage of the capsules. | 12-19-2013 |
| 20140018731 | SAFETY SYRINGE FOR NEEDLELESS INJECTOR - A disposable syringe for use in a needleless injector includes a tubular body with an open rear end, a closed front end containing an injection orifice, a chamber in the body for receiving a liquid and a plunger slidable in the chamber for pushing the liquid out of the orifice. A tip is provided on the inner end of the plunger for separation from the remainder of the plunger to block the orifice when the plunger is retracted after an injection, whereby the syringe cannot be re-used. | 01-16-2014 |
| 20140107568 | METHOD OF DETERMINING AN INJECTED DOSE BASED ON A KNOWN ORAL DOSE - The present disclosure relates to methods of determining dosages of compositions used in injection devices, in view of known oral doses of the same compositions. | 04-17-2014 |
| 20140128805 | DEVICES, SYSTEMS, AND METHODS FOR DELIVERING FLUID TO TISSUE - A needleless fluid injection device including a flexible shaft with a proximal end, a distal end, an injection lumen extending from the proximal end to the distal end of the shaft, and at least one injection orifice extending through a wall of the injection lumen at the distal end of the shaft. The injection lumen can include a depth-limiting system ( | 05-08-2014 |
| 20140142500 | PISTON CLOSURES FOR DRUG DELIVERY CAPSULES - A drug capsule and a method for making a drug capsule for a drug delivery device, such as an auto injector or needle-free injector, with improved stability and container closure integrity. The injector comprises a drug capsule sealed by a piston fabricated from PTFE modified by the inclusion of a co-polymer of PPVE, preferably in an amount less than 1% by weight, resulting in better performance while the device is stored and subjected to temperature cycling. | 05-22-2014 |
| 20140243740 | CYLINDER-PISTON UNIT WITH ADHESIVE DISC I - A cylinder-piston unit of a needle-free injector, with at least one cylinder accommodating an injection solution, at least one piston, and an adhesive coating arranged in the area of the free end face of the cylinder. The cylinder has a bottom portion, on which a discharge tube is arranged. An adhesive disc, which is displaceable in the direction of the centre line of the cylinder-piston unit between an installation position and an application position, is arranged on the discharge tube and/or on the bottom portion. The adhesive disc has an adhesive coating on each of the two end faces. In the installation position, the discharge tube can be sealed off in the adhesive disc. In the application position, the front edge of the discharge nozzle lies in the plane of the front adhesive coating or protrudes beyond this plane by at least 0.5 mm. A needle-free cylinder-piston unit of an injector whose discharge system is suitable for safely penetrating the outer layers of skin, covered by the term “dermis”, in order to convey the injection solution into or under the skin. | 08-28-2014 |
| 20140249470 | CYLINDER-PISTON UNIT WITH MULTI-PART PISTON - A cylinder-piston unit, of a needle-free injector, with at least one cylinder accommodating an injection solution, and with at least one piston. The piston is composed of a drive body and of a sealing body. The sealing body is at least one elastic disc, which bears under a radial clamping action against the inner wall of the cylinder. The drive body is a pot-shaped body with a peripheral elastic skirt. At least one area of the skirt bears under a radial clamping action against the inner wall of the cylinder. The cylinder chamber areas located in front of and behind the drive body communicate with each other via at least one recess. The drive body is arranged behind the sealing body in the cylinder, and the skirt faces towards the sealing body. A piston is developed which, at ambient pressure, can be set down on the liquid level of a filled cylinder in a bubble-free, sterile and gas-tight manner and which nevertheless withstands a high compression pressure without leakage during the targeted emptying of the cylinder-piston unit. | 09-04-2014 |
| 20140249471 | CYLINDER-PISTON UNIT WITH ADHESIVE DISC II - A cylinder-piston unit, with at least one cylinder accommodating an injection solution, at least one piston, and an adhesive coating arranged in the area of the free end face of the cylinder. The cylinder has a bottom portion, on which a discharge tube is arranged. An adhesive disc, which is displaceable in the direction of the centre line of the cylinder-piston unit between an installation position and an application position, is arranged on the discharge tube and/or on the bottom portion. On its end face directed away from the bottom portion, the adhesive disc has an adhesive coating. In the storage position, the adhesive disc has at least one sealing element or a sealing area for closing the discharge tube, the effect of which sealing element or sealing area is no longer present in the application position. In the application position, the front edge of the end face of the discharge tube protrudes at least 0.5 mm beyond the adhesive coating of the adhesive disc. A cylinder-piston unit of an injector is developed whose discharge system is suitable for safely penetrating the outer layers of skin, covered by the term “dermis”, in order to convey the injection solution into or under the skin and keep it there for a definable period of time. | 09-04-2014 |
| 20140296776 | CASING - A casing for an injection device of the type having a safety device which prevents operation of the device, incorporating an actuator means by which the safety means of the device can be actuated to allow operation of the device. Also a casing for a medicament container having an opening closed prior to use by a break-off tip, having relatively moveable first and second casing parts, which on relative movement apply a breaking force to the break-off tip. A preferred embodiment includes both such features. | 10-02-2014 |
| 20140358073 | PISTON FOR A NEEDLELESS VALVE SYSTEM - A piston for a needleless valve system comprising a head portion configured to be disposed in the needleless valve system and controlling fluid flow through the needleless valve system. The head portion comprising a continuous top surface, and an opening disposed proximate the continuous top surface, wherein the continuous top surface is non-planar when the opening is in an open position. | 12-04-2014 |
| 20140371669 | NEEDLELESS INJECTOR - A needleless injector has a syringe body having an opening at one end, a piston housed within the syringe body for urging a liquid within the syringe body through the opening and a ram for driving the piston. A shock absorbing component is provided for reducing an initial transfer of force from the ram to the piston. The initial rate of pressure increase on the liquid is reduced, thereby controlling the rate of collapse of gas bubbles in the liquid. | 12-18-2014 |
| 20150105720 | Therapeutic Agent Injection Device - A therapeutic agent injection device including an injection device for delivering a therapeutic agent to a patient having a body, the body having a patient face and an port face opposite the patient face, the port face having an introducer port including an introducer channel and an injection port including an injection channel, the introducer channel being in fluid communication with the injection channel through a cross channel, the injection channel defining an injection axis; a delivery tube for subcutaneous delivery of the therapeutic agent to the patient, the delivery tube projecting from and being generally perpendicular to the patient face, the delivery tube defining an introducer axis and being in fluid communication with the injection port; and a patch, the patch being attached to the patient face and being operable to adhesively attach to the patient; wherein the injection axis is parallel to the introducer axis. | 04-16-2015 |
| 20150119799 | Hazardous Agent Injection System - Injection systems comprising a powered injector and one or more hazardous agents are disclosed. | 04-30-2015 |
| 20160008543 | INJECTOR WITH ADJUSTABLE DOSING | 01-14-2016 |
| 20160151571 | NOVEL FORMULATIONS FOR TREATMENT OF MIGRAINE | 06-02-2016 |
| 20180021516 | DISPOSABLE INJECTOR HAVING A SOUND-PROOFING LAYER | 01-25-2018 |
