Class / Patent application number | Description | Number of patent applications / Date published |
604521000 | Therapeutic material to facilitate ocular treatment | 46 |
20080281292 | Retractable Injection Port - A cannula, for delivering a bolus of a pharmaceutically active agent to the posterior chamber of the eye, having an orifice disposed at the distal tip. The cannula is slidably disposed within a hypodermic needle. The sliding action of the cannula within the needle provides a means for trimming a formed bolus of a pharmaceutically active agent from the orifice of the cannula. In addition, the double wall formed by the cannula within the needle provides insulation from the cooler temperatures within the eye to allow for the delivery of phase transition substances. | 11-13-2008 |
20090005756 | Methods and Systems of Treating Strabismus - Methods and systems of treating a patient with strabismus include providing a stimulator, configuring one or more stimulation parameters to treat strabismus, programming the stimulator with the one or more stimulation parameters, generating a stimulus configured to treat strabismus with the stimulator in accordance with the one or more stimulation parameters, and applying the stimulus with the stimulator to one or more of the extraocular muscles and/or one or more cranial nerves that innervate the extraocular muscles in accordance with the one or more stimulation parameters. | 01-01-2009 |
20090118702 | Treatment Medium Delivery Device and Methods for Delivery of Such Treatment Mediums to the Eye Using such a Delivery Device - Featured are devices for delivering a treatment medium to an eye as well as methods related thereto. Such devices and methods allow a desired amount of the treatment medium to be delivered in a controllable manner over a predetermined time period. In particular embodiments, the delivery device is configured and arranged so the treatment medium is eluted from one portion of the delivery device and so that another portion thereof is removably secured within a natural opening or orifice in or proximal to the eye. In specific embodiments the another portion is configured and arranged so as to be removably secured within the natural opening comprising at least one punctum of an eye. | 05-07-2009 |
20090118703 | DRUG DELIVERY SYSTEMS AND METHODS - A delivery system includes a housing along with a tip connected to one end of the housing. A first cannula extending from the tip is provided for inserting a rod implant into tissue. A second cannula, concentrically disposed within the first cannula, is utilized to force the rod implant from the first cannula and for ejecting a fluid behind the inserted rod implant in the tissue. | 05-07-2009 |
20090137983 | IMPLANT DELIVERY DEVICE AND METHODS THEREOF FOR TREATMENT OF OCULAR DISORDERS - Implants and methods for treating ocular disorders are described. One method involves providing an elongated delivery device and an implant mounted at a distal end of the delivery device. An incision is formed in eye tissue and the implant is inserted the through the incision using the delivery device. The implant is implanted at a location communicating with a physiologic outflow pathway of an eye such that a distal end portion of the implant and a proximal end portion of the delivery device are relatively disposed in a non-linear orientation during implantation. In one method, the implant is non-linear after insertion. | 05-28-2009 |
20090264861 | Lacrimal implants and related methods - Lacrimal implants and related methods providing secure retention within the lacrimal punctum of an eye are described. The lacrimal implants can comprise a implant body configured for at least partial insertion through the lacrimal punctum and into a lacrimal canaliculus. The implant body can include a deformable retention structure that can be configured to substantially encapsulate an expandable retention element. In some examples, the expandable retention element can include a fluid absorbing material, which can be exposed to fluid such as via a fluid permeable retainer or a fluid permeable aperture. As the fluid absorbing material retains fluid (i.e., upon acceptance of fluid into the retention structure), its size increases and its shape can change to urge one or more portions of the retention structure outward, such as against a wall of the lacrimal canaliculus, thereby securely retaining the lacrimal implant within the punctum. | 10-22-2009 |
20100004630 | EYE COLORING SYSTEMS - A novel system for coloring tissues of the human eye, especially methods of coloring the iris, includes drying the tissue surface, applying colorant to the dried surface, and then drying the applied colorant. The system avoids tattooing, implanting, and corneal modification. Permanent results may be obtained. Colorants may be coatings or stains. | 01-07-2010 |
20100211044 | BATTERY OPERATED SURGICAL HAND PIECE WITH DISPOSABLE END - The present invention is an ophthalmic injection system with a limited reuse assembly and a tip segment. The tip segment is connectable to and removable from the limited reuse assembly. The tip segment includes a dispensing chamber, a plunger, and a housing. The dispensing chamber holds a quantity of a substance to be injected into an eye. The proximate end of the plunger has a first mechanical linkage interface. The limited reuse assembly of the ophthalmic injection system has a power source, a controller, a motor, a second mechanical linkage interface located on an end of the motor shaft; and a second housing. The first mechanical linkage interface is mateable with the second mechanical linkage interface such that when the tip segment is connected to the limited reuse assembly, the first mechanical linkage interface mates with the second mechanical linkage interface so that motion of the shaft results in motion of the plunger. | 08-19-2010 |
20110054445 | Devices and Methods for Treatment of Eye Disease - Methods, systems, and apparatus for delivering drugs for treatment of eye disease are described. For example, the methods, systems, and apparatus can be optionally used to treat wet age-related macular degeneration. In some examples, an eye disease is treated by implanting a device comprising a sealed container into the diseased eye. A dosage of drug for treating the diseased eye is disposed within the sealed container. The dosage of the drug is selectively released from the sealed container of the implanted device into eye tissue. The released dosage treats the eye disease. | 03-03-2011 |
20110066138 | Lacrimal filler - A biomaterial mass is inserted through a punctum into a canaliculus in the lacrimal outflow system with a syringe. The mass has an outer cross section that is less than the inner cross section of the canaliculus. The mass absorbs liquid to swell to form a lacrimal filler or sealing mechanism. The lacrimal filler has an external cross section that conforms to the internal cross section of the canaliculus and a soft outer surface relative to the surrounding tissues to prevent erosion of the canaliculus lining. The lacrimal filler forms an occlusion that prevents the outflow of liquid through the lacrimal outflow system to retain tears within the eye to maintain eye lubrication and wetness. The mass and syringe are provided in kit with a rubber stopper and, optionally, a punctal dilator, an injecting catheter, and an enzyme for dissolving or degrading the lacrimal filler at a later time. | 03-17-2011 |
20110190728 | DYE SOLUTION - The invention relates to a water-based biocompatible non-cytotoxic preparation for the selective staining of internal limiting membrane (ILM) and/or epiretinal membranes (ERM) in the human or animal eye, and to a kit containing said water-based preparation according to the invention. | 08-04-2011 |
20120083765 | Drug Introduction and Placement System - A drug introduction sleeve is disclosed that includes a selectively expandable body portion. The body portion is defined by a first open end and a second open end. A hollow interior is formed within the body portion. The body portion is selectively expandable from a first unexpanded configuration to a second expanded configuration whereby the volume of the hollow interior is increased when the body portion is expanded to the second expanded configuration, sufficient to temporarily retain a drug bolus. | 04-05-2012 |
20130304031 | Reservoir Device for Intraocular Drug Delivery - A delivery device that allows for the sustained release of an agent, particularly useful for the sustained release of a therapeutic agent to limited access regions, such as the posterior chamber of the eye and inner ear. The delivery device is minimally invasive, refillable and may be easily fixed to the treatment area. The delivery device includes a hollow body with an inlet port at its proximal end for insertion of the agent, a reservoir for holding the agent and a delivery mechanism for the sustained delivery of the agent from the reservoir to the patient. | 11-14-2013 |
20140148792 | Laser-Activated Drug Delivery Device - Devices and methods are provided for selectively delivering a drug by laser activation. The device includes structural elements forming a hermetic, enclosed reservoir, and at least one drug unit contained in the enclosed reservoir. The at least one drug unit includes a drug. The device is able to absorb laser irradiation effective to open the enclosed reservoir to permit release of the drug. The method includes implanting a drug delivery device into a tissue site of a patient, and irradiating at least a portion of the drug delivery device to breach the enclosed reservoir to permit the drug to be released in tissues at the tissue site. | 05-29-2014 |
20140180253 | LACRIMAL IMPLANTS AND RELATED METHODS - Lacrimal implants for treating diseases or disorders are disclosed. More particularly, lacrimal implants, methods of making such implants, and methods of treating ocular, respiration, inner ear or other diseases or disorders using such implants are disclosed. | 06-26-2014 |
20140243795 | Reservoir Device for Intraocular Drug Delivery - A delivery device that allows for the sustained release of an agent, particularly useful for the sustained release of a therapeutic agent to limited access regions, such as the posterior chamber of the eye and inner ear. The delivery device is minimally invasive, refillable and may be easily fixed to the treatment area. The delivery device includes a hollow body with an inlet port at its proximal end for insertion of the agent, a reservoir for holding the agent and a delivery mechanism for the sustained delivery of the agent from the reservoir to the patient. | 08-28-2014 |
20140249509 | OPHTHALMIC TREATMENT SOLUTION DELIVERY DEVICES AND DELIVERY AUGMENTATION METHODS - A first sponge device for use to manipulate and prepare the surface of the epithelium of an eye prior to application of an ophthalmic solution has a handle and a sponge head secured to the handle. The head is made of an absorbent, wicking sponge material and has a non-sharp, tissue preparation surface of predetermined shape for rubbing across the surface of the epithelium layer in order to manipulate the tissue. After the surface is prepared, a second, holding sponge is placed over the eye to act as a reservoir and to hold ophthalmic solution against the eye surface. | 09-04-2014 |
20140276638 | SYSTEM AND METHOD FOR PROVIDING PRESSURIZED INFUSION - The present invention relates generally to providing pressurized infusion of liquids and, more particularly, is directed to providing a stable and pressurized flow of irrigation fluid to the eye during surgery. | 09-18-2014 |
20140276639 | SYSTEM AND METHOD FOR PROVIDING PRESSURIZED INFUSION - The present invention relates generally to providing pressurized infusion of liquids and more particularly, is directed to providing a stable and pressurized flow of irrigation fluid to the eye during surgery. | 09-18-2014 |
20140336618 | SPRAY EJECTOR MECHANISMS AND DEVICES PROVIDING CHARGE ISOLATION AND CONTROLLABLE DROPLET CHARGE, AND LOW DOSAGE VOLUME OPHTHALMIC ADMINISTRATION - The present disclosure relates to ejector mechanisms and devices for generating a directed stream of droplets, as well as improved methods for delivering an ejected stream of droplets to a target. The device and methods may be useful for the delivery of fluid for ophthalmic, topical, oral, nasal, or pulmonary use, more particularly, for use in the delivery of ophthalmic fluid to the eye. Certain aspects of the disclosure relate to devices and methods for the delivery of a therapeutically effective low dosage volume medicament composition to a target, e.g., by controlling charge, droplet size and/or droplet deposit parameters of the medicament composition. | 11-13-2014 |
20140336619 | OPHTHALMIC SHUNT AND METHOD - An ophthalmic shunt includes a seal or septum through which multiple injections of the therapeutic agent can be made as needed, thereby avoiding repeated injury to the sclera. The therapeutic agent is temporarily carried in a tube connected to the septum. The therapeutic agent release may be rapid or sustained over a period of time. | 11-13-2014 |
20140358124 | Approach to administering ocular medication - The invention is a device and a method for delivering a dose of a pharmaceutical agent to the eye. The device and method provide a safe and effective way to instill a specified dose of the agent to the eye virtually independent of gravity and posture. The device includes a filter matrix in which the fluid capture and release properties can be modified. The filter matrix is attached to a flexible handle with an impermeable or semipermeable membrane there between. | 12-04-2014 |
20140358125 | SMALL MOLECULE DELIVERY WITH IMPLANTABLE THERAPEUTIC DEVICE - A therapeutic device that can release a therapeutic agent comprising a porous structure coupled to a container comprising a reservoir. The reservoir can comprise a volume sized to release therapeutic amounts of the therapeutic agent for an extended time when coupled to the porous structure and implanted in a patient. The porous structure may comprise a first side coupled to the reservoir and a second side to couple to the patient to release the therapeutic agent. The length of the channels extending from the first side to the second side may comprise an effective length greater than a distance across the porous structure from the first side to the second side. The therapeutic device may comprise a penetrable barrier to inject therapeutic agent into the device when implanted in the patient. | 12-04-2014 |
20150025506 | APPARATUS AND METHOD FOR FLUID DELIVERY - The present invention relates to an apparatus and method for delivering a fluid, and particularly, but not exclusively, to an apparatus and method for delivering a fluid to an eye. The apparatus provides a useful device that assists users to accurately deliver fluid to the eye and includes features that make using the apparatus more comfortable. | 01-22-2015 |
20150088099 | EYE DROP ASSIST APPARATUS - An eye drop assist apparatus and method for sequentially administering an ocular medication into a patient's eyes. A bottle or vial containing liquid eye drops is supported in a holder. First and second nasal locators extend in opposite directions from the holder. The nasal locators are separated by the pupillary distance (typically 60 mm), with the dispensing tip of the bottle located mid-way between. A person administering eye drops abuts the first nasal locator against the top of the patient's nasal bridge while aligning the tip of the bottle directly over a first eye before squeezing the bottle to forcibly expel one or more drops into the first eye. The person then linearly translates the bottle so that the second nasal locator abuts against the top of the patient's nasal bridge while aligning the tip of the bottle directly over a second eye. The bottle is then squeezed again to forcibly expel drops into the second eye. | 03-26-2015 |
20150126970 | CONJUNCTIVAL COVER AND METHODS THEREFOR - A conjunctival cover including an annular generally curved shell having a conjunctival portion structured to conform to and overly at least part of the conjunctiva of an eye. The annular generally partially spherical shell defines a generally central opening. The central opening is sized to leave a cornea of the eye substantially or partially uncovered when the conjunctival cover is applied to the eye. | 05-07-2015 |
20150133895 | DEVICE FOR ADJUSTING THE IRRIGATION PRESSURE IN EYE OPERATIONS - The invention relates to a device ( | 05-14-2015 |
20150133896 | BIORESORBABLE DRUG ELUTING INTRAVITREAL IMPLANT SYSTEM AND METHOD - A bioresorbable drug eluting intravitreal implant system includes a syringe with a chamber containing a medicinal drug. A balloon is releasably secured to a needle where the needle has a central section chamber in fluid communication with a chamber in the syringe. The needle central section has an opening formed through a wall for transporting the medicinal drug to the interior of the balloon subsequent to insertion of the needle through the sclera of a patient's eye. | 05-14-2015 |
20150305929 | MAGNETIC CONTACT LENSES AND METHODS OF TREATMENT AND DIAGNOSIS USING THE SAME - In certain aspects, the invention is directed to magnetic contact lenses that comprise one or more magnets. When worn by a patient, the magnetic contact lenses are configured to generate an intraocular magnetic field of sufficient magnitude and direction to move a magnetic therapeutic and/or diagnostic agent positioned inside the eye to target tissue within the eye. Other aspects of the invention pertain to kits which comprise such magnetic contact lenses as well as one or more additional components, for example, one or more containers of a magnetic diagnostic and/or or therapeutic agent. Further aspects of the invention pertain to methods of treatment, which comprise intraocularly introducing a magnetic therapeutic and/or diagnostic agent into an eye of a patient and fitting a magnetic contact lens to the head of the patient, wherein the magnetic therapeutic and/or diagnostic agent may be introduced to the patient before or after fitting the magnetic contact lens to the head of the patient. | 10-29-2015 |
20150305930 | VACUUM-ASSISTED DRUG DELIVERY DEVICE AND METHOD - This invention relates to a device and method for the vacuum-assisted delivery of drugs through an intact surface membrane of an organ. | 10-29-2015 |
20150305931 | METHOD AND OPHTHALMIC DEVICE WITH ACTIVE AGENT RELEASE SYSTEM - The present invention provides an energized ophthalmic device with an active agent release system and an associated method. The active agent release system can be suitable to dispense an active agent including, for example, a vitamin, lubricant, a saline, a solvent, and/or medicament, at one or more predetermined times, through the use of an energization element contained in the ophthalmic device. The energization element may be a battery and/or an energy receptor antenna. The release of the active agent can be according to a signal received wirelessly, a predetermined time, and/or a sensed condition, which can cause an activation element to conduct a current to at least a portion of a metal cap under stress causing it to fold and thereby expose the active agent to a surrounding environment. | 10-29-2015 |
20150313757 | EYE DROPPER - An eye dropper bottle including a notch for resting on the bridge of a nose is provided. The eye dropper bottle may include a curved neck with a nozzle. The nozzle may be oriented at an angle relative to the bottle. A user may place the notch on the bridge of the nose so that the nozzle is disposed over the eye. The user may then squeeze the bottle to dispense the liquid into the eye. | 11-05-2015 |
20150335475 | Device for dispensing drops - A device for dispensing drops of a liquid or semi-liquid product, includes:
| 11-26-2015 |
20150351958 | THERAPEUTIC AGENT DELIVERY DEVICE WITH CONVERGENT LUMEN - An apparatus has a first fluid conduit, a second fluid conduit, a connector member, an first tubular member, a second tubular member, and an inner cannula. The connector member has first and second passageways in which the first and second fluid conduits are positioned, respectively. A portion of the second tubular member is positioned within the lumen of the first tubular member. A proximal portion of the inner cannula is fixedly secured within the lumen of the first tubular member. The inner cannula lumen is in fluid communication with the first and second fluid conduits via the lumen of the first tubular member and the lumen of the second tubular member. The inner cannula may be inserted into the subretinal space of a human eye to deliver a leading bleb of fluid and then deliver a therapeutic agent, without having to withdraw the inner cannula from the subretinal space between the acts of delivering the leading bleb delivering the therapeutic agent. | 12-10-2015 |
20150351959 | SUB-RETINAL TANGENTIAL NEEDLE CATHETER GUIDE AND INTRODUCER - An apparatus includes a body, a needle, a catheter, and an actuator assembly. The needle extends distally from the body. The needle has an inner wall defining a needle lumen. The needle lumen is in fluid communication with a fluid port of the body. The catheter is slidably disposed in the needle lumen. The catheter has a catheter lumen. The first actuator assembly is configured to translate the catheter within and relative to the needle. The apparatus may also include an actuator assembly that is configured to rotate the needle relative to the body. The apparatus may be used to first deliver a leading bleb of fluid to the subretinal space in a patient's eye via the needle. The apparatus may then be used to deliver a therapeutic agent to the subretinal space in the patient's eye via the catheter. | 12-10-2015 |
20150351960 | Guide for an Eye Drop Dispenser Bottle for the Self-Administration of Eye Drops - The guide ( | 12-10-2015 |
20150351961 | LACRIMAL SYSTEM DRUG DELIVERY DEVICE - This invention is in the field of medical intervention related to the lacrimal system. The invention relates to a lacrimal system device and methods of using the device for drug delivery to the eye, sinuses and/or periocular tissues. | 12-10-2015 |
20150374542 | Ophthalmic Devices For Delivery Of Beneficial Agents - Contact lenses comprising phosphorylcholine groups release beneficial polyionic or guanidinium-containing agents. | 12-31-2015 |
20160022486 | Drug Delivery Devices And Methods - This disclosure relates generally to methods and devices for use in treating eye conditions with implantable drug delivery devices. One method includes introducing an implant into the suprachoroidal space, wherein the interior volume of the implant is plugged with a drug-release material comprising at least one active agent that elutes through at least one opening in the implant, wherein the drug-release material degrades from the interior volume of the implant over a period time. | 01-28-2016 |
20160038412 | SUSTAINED RELEASE DRUG DELIVERY DEVICES, METHODS OF USE, AND METHODS OF MANUFACTURING THEREOF - A method and device for treating a mammalian organism to obtain a desired local or systemic physiological or pharmacological effect is provided. The method includes administering a sustained release drug delivery system to a mammalian organism in need of such treatment at an area wherein release of an effective agent is desired and allowing the effective agent to pass through the device in a controlled manner. The device includes an inner core or reservoir including the effective agent, an impermeable tube which encloses portions of the reservoir, and a permeable member at an end of the tube. | 02-11-2016 |
20160038680 | SUBCONJUNCTIVAL INJECTOR AND METHOD - An injection device and method are shown. Devices and methods include a forceps and a needle advancement mechanism to clamp a portion of tissue and control a depth of penetration of the needle between gripping ends of the forceps. An injection device and method are shown where selected components of the injection device such as a syringe and forceps are disposable, while the remaining portions of the injection device are reusable. Devices and methods are shown that utilize micro-needles to control a depth of penetration. | 02-11-2016 |
20160106583 | IMAGE-GUIDED DELIVERY OF OPHTHALMIC THERAPEUTICS - Systems and methods are provided for image-guided delivery of therapeutics to an eye. An optical coherence tomography (OCT) imager is configured to produce at least one OCT image of the eye. A therapeutic delivery system is configured to deliver a therapeutic to the eye through a distal end of a delivery mechanism. A system control is configured to determine a position of the distal end of the delivery mechanism and control the therapeutic delivery system according to at least the determined position. | 04-21-2016 |
20160158060 | OPHTHALMIC SHUNT AND METHOD - An ophthalmic shunt includes a seal or septum through which multiple injections of the therapeutic agent can be made as needed, thereby avoiding repeated injury to the sclera. The therapeutic agent is temporarily carried in a tube connected to the septum. The therapeutic agent release may be rapid or sustained over a period of time. | 06-09-2016 |
20160193079 | APPROACH TO ADMINISTERING OCULAR MEDICATION | 07-07-2016 |
20190142634 | METHOD AND APPARATUS FOR SUBRETINAL ADMINISTRATION OF THERAPEUTIC AGENT | 05-16-2019 |
20190142635 | METHOD AND APPARATUS FOR SUBRETINAL ADMINISTRATION OF THERAPEUTIC AGENT | 05-16-2019 |