| Entries |
| Document | Title | Date |
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| 20080300571 | PROCESS AND DEVICE FOR SELECTIVELY TREATING INTERSTITIAL TISSUE - A method and apparatus for direct interstitial treatment of tissue, while preventing backflow and decreasing drainage of a flowable composition from an injected area, by using a catheter and/or a needle with single or multiple inflatable member(s) that stretches, dilates and compresses target tissue and allows for an improved interstitial deposition, distribution and retention of the flowable composition, drug(s), agent(s), or particle(s), into a body organ, fluid, tissue, or tumor, thereby increasing procedural safety and efficacy of direct interstitial therapies. | 12-04-2008 |
| 20090069787 | Activity Sensing Techniques for an Infusion Pump System - Some embodiments of a wearable infusion pump system can include a pump device having a drive system to dispense a medicine to a user, an activity sensor that detects a possible change in an activity level of the user, and a controller to activate the drive system to dispense the medicine to the user. The controller device can query the user to indicate whether a detected activity level of the user represents an actual change in the activity level of the user. The controller device can alter the medicine dispensing schedule based on the user indicated changes in activity level. | 03-12-2009 |
| 20090112178 | FLUID TRANSFER PORT INFORMATION SYSTEM - Methods are provided for associating a specific one of two or more distinct fluid transfer ports of a patient with a given fluid transfer event of fluid from a parenteral fluid delivery device. Aspects of the methods include establishing a fluid transfer connection between the parenteral fluid delivery device and the patient via one of the two or more distinct fluid transfer ports and transmitting a fluid transfer signal between the parenteral fluid delivery device and a patient associated identifier using the patient's body as a signal conduction medium. Association may result in identification of the fluid transfer port that will be, is being or has been employed for the given fluid transfer event. Also provided are systems for practicing methods of the invention. | 04-30-2009 |
| 20090118696 | APPARATUS AND METHODS FOR THE CONTROLLABLE MODIFICATION OF COMPOUND CONCENTRATION IN A TUBE - Methods for delivery of a compound within a tube. | 05-07-2009 |
| 20090118697 | CLOSED LOOP ANESTHETIC DELIVERY - A method for delivering a sedation drug comprising administering a drug to a patient while requesting the patient to respond to an instruction, monitoring a patient's BIS values, bringing the patient to a level of anesthesia where the patient fails to respond to the request within a predetermined response time, and determining a BIS value that coincides with the level of anesthesia corresponding to the failure to respond. | 05-07-2009 |
| 20090137980 | METHOD AND APPARATUS FOR MULTI-INPUT STEPWISE INFUSION PRESCRIPTION - A drug infusion system includes a drug delivery module which delivers a drug in each of a series of sequential time slots over a period of time. The drug delivery module is controlled by a controller which is configured to cause the drug delivery module to deliver said drug in the series of sequential time slots in a manner defined by a formula in which a quantitative characteristic of drug delivery in each time slot is a function of a past drug delivery profile and at least one of: a) a medical professional-provided profile, b) a patient-chosen parameter, and c) a non-variable parameter. The formula may be a function of a medical professional-provided profile and a non-variable parameter may be a parameter chosen by a medical professional. The past drug delivery profile may include a drug delivery parameter in a previous time slot. The patient-chosen parameter may include an input from the patient characterizing the patient's condition. | 05-28-2009 |
| 20090177181 | DEVICE AND PROCESS FOR CONTROLLING THE DEPTH OF SEDATION OF A MECHANICALLY RESPIRATED PATIENT - A device is provided for controlling the depth of sedation of a respirated patient. The device includes a respirator ( | 07-09-2009 |
| 20090187159 | CHRONICALLY IMPLANTABLE HYBRID CANNULA-MICROELECTRODE SYSTEM FOR CONTINUOUS MONITORING ELECTROPHYSIOLOGICAL SIGNALS DURING INFUSION OF A CHEMICAL OR PHARMACEUTICAL AGENT - A device for assessing the effects of diffusible molecules on electrophysiological recordings from multiple neurons allows for the infusion of reagents through a cannula located among an array of microelectrodes. The device can easily be customized to target specific neural structures. It is designed to be chronically implanted so that isolated neural units and local field potentials are recorded over the course of several weeks or months. Multivariate statistical and spectral analysis of electrophysiological signals acquired using this system could quantitatively identify electrical “signatures” of therapeutically useful drugs. | 07-23-2009 |
| 20090204100 | BODY COVER AND A METHOD OF COMMUNICATING A VARIATION IN TEMPERATURE OF THE SKIN - Body cover for application to the skin, comprising at least one temperature sensing element, wherein the body cover is substantially flexible, wherein the at least one temperature sensing element, when applied to the skin, is configured to sense the temperature of proximate skin at least locally with respect to the body cover and to convert the locally sensed temperature into a visual and/or electrical signal. | 08-13-2009 |
| 20090209937 | Apparatus and Methods for Treating Epilepsy Using Convection-Enhanced Delivery - Disclosed herein are apparatuses and methods for treating a neurological disorder associated with excessive neuronal excitability (e.g., epilepsy). Methods disclosed herein comprise administering to a subject in need of such treatment an antiepileptic drug solution comprising a therapeutically effective amount of an antiepileptic drug (e.g., a toxin that inhibits the exocytosis of neurotransmifters, excitotoxins, etc.) using convection-enhanced delivery (CED). | 08-20-2009 |
| 20090209938 | APPARATUS AND METHOD FOR DOSING DRUG AND WIRELESS REMOTE CONTROL OF A DRUG PUMP - The invention comprises an apparatus meant to be carried by a user for dosing a drug, a method for dosing drug and a wireless remote control for a drug pump. The apparatus comprises a drug pump ( | 08-20-2009 |
| 20090221986 | METHOD AND APPARATUS FOR A FLUID DELIVERY SYSTEM WITH CONTROLLED FLUID FLOW RATE - The present invention includes systems and methods for medical fluid delivery. Such system may comprise a fluid flow path for communication between a fluid source and a patient. A flow valve is operatively associated with the path and movable between a first position, which allows fluid flow through the path, and a second position, which limits fluid flow through the path. A control module is operatively associated with the valve to move the valve between the first and second positions in response to a measured actual fluid flow rate in the path. Such method may comprise flowing a fluid through a fluid flow path between a portable fluid source and a patient; determining an actual fluid flow rate through the path; and changing the actual fluid flow rate in response to a difference between the actual fluid flow rate and a desired fluid flow rate. Such method may further include a plurality of settings for a desired flow rate according to a sensed pain level of the patient. | 09-03-2009 |
| 20090281518 | DEVICE FOR AUTOMATIC ADJUSTMENT OF THE DOSE OF MELATONIN AND/OR DELIVERY OF MELATONIN - The invention relates to a device for melatonin treatment involving an adapting means which adapts the daily dose upon measurement of a body parameter of the patient or the user of the device. | 11-12-2009 |
| 20090326509 | CONTEXT AWARE MEDICAL MONITORING AND DOSAGE DELIVERY DEVICE - A device and method for medical monitoring and therapeutic dosage control and delivery is disclosed. | 12-31-2009 |
| 20090326510 | Drug Delivery Methods and Systems - Drug delivery methods and systems that include a determination of whether a cardiac condition is normal or abnormal, so that a drug may be administered in accordance with that determination. In one implementation, a drug delivery device may be controlled to reduce or stop the drug administration when a normal cardiac condition is detected. In another implementation, a patient monitoring device determines the duration that a cardiac condition is normal and provides an output indicative of the determination so that the patient may alter a therapy accordingly. | 12-31-2009 |
| 20100004624 | MEASURING PROPERTIES OF AN ANATOMICAL BODY - A medical device includes a sensor that is configured to measure a property of an outer layer of an anatomical body surface. The sensor includes a source probe configured stimulate a local surface of the outer layer of an anatomical body surface. The sensor also includes a detector configured to measure a response of the outer layer resulting from the source probe stimulation. A controller coupled to the source probe and the sensor drives the source probe using a tailored stochastic sequence and determines the property of the outer layer using the measured response received from the detector. The sensor can be used with medical devices, such as drug delivery devices including microneedle transport devices and needleless injection devices. | 01-07-2010 |
| 20100082011 | FLUID DETECTION IN AN ENTERAL FEEDING SET - Detection of fluid conditions in an administration set. A light source is positioned to transmit an infrared light through administration set tubing and any fluid therein. A light sensor senses the infrared light transmitted through the tubing and generates an output signal. A frequency of the output signal is a function of an intensity of the light transmitted through the tubing. A processor receives and determines the frequency of the output signal, and compares the determined frequency to threshold frequency values to determine whether fluid is in the tubing. The processor also monitors the generated output signal to determine if the frequency of the output signal changes over time, and determines whether fluid is flowing in the tubing as a function of the determined change in frequency. | 04-01-2010 |
| 20100137828 | DEVICE FOR INFUSION OF AT LEAST TWO MEDICAMENTS - A device for infusing of at least one medicament includes at least two actuators configured to cause at least two medicaments to be infused; at least one sensor configured to measure a value of at least two parameters; and a controller configured to control the at least two actuators, wherein the controller is programmed to activate the at least two actuators depending on the values of each of the at least two parameters, and wherein the controller is arranged so as to consider a dependency of the at least two medicaments. | 06-03-2010 |
| 20100145301 | SPRAY ADMINISTRATION OF COMPOSITIONS INCLUDING ACTIVE AGENTS SUCH AS PEPTIDES TO THE GASTROINTESTINAL TRACT - Methods of administering an active agent such as an active pharmaceutical ingredient by spraying a composition comprising the active agent at a luminal wall of the gastrointestinal tract are disclosed. Also disclosed are devices for administering a composition suitable for implementing the disclosed method. Also disclosed is the use of a peptide as an active agent for the manufacture of a sprayable composition for use in the treatment of a subject by gastrointestinal administration. | 06-10-2010 |
| 20100185174 | Systems, devices, and methods for making or administering frozen particles - Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one substrate. | 07-22-2010 |
| 20100204676 | METHOD AND APPARATUS FOR CHEMICAL DETECTION AND RELEASE - A nano-sniffer is provided for detecting chemicals and/or releasing chemicals based on detection of a chemical. The nano-sniffer may be less than about 150 nanometers in size. The nano-sniffer may be a passive, active, or semi-passive nano-sniffer. The nano-sniffer may be distributed to a subjects such as a human or animal or products, for example. The nano-sniffer may include a nano RFID component, including nano antennae that may comprise one or more carbon tubes. The nano-sniffer may include a nano battery. The nano-sniffer may include an environmentally reactive shell that reacts to its immediate environment to affix or adhere to a subject. The nano-sniffer may be constructed for direct or indirect distribution techniques such as by airborne techniques for inhalation, consumption distribution for ingestion, and contact distribution, for example. | 08-12-2010 |
| 20100234827 | METHOD OF TREATING HEART FAILURE - The present invention includes methods, systems, uses, and means for the delivery of one or more anti-fibrotic agents into the pericardial space for the treatment and prevention of heart failure (HF). | 09-16-2010 |
| 20100241100 | Real-time multimode neurobiophysiology probe - Apparatus and methods in which very small volumes of material may be extracted, delivered, interrogated or stimulated via optical, electromagnetic or mechanical means, in vivo or in vitro, for site-specific detection, characterization, stimulation, diagnostics or therapy, comprising optical, fluidic, chemical, electromagnetic and biological techniques applied via a microprobe in a single intra-parenchymal tissue perforation procedure in the brain. The primary use of the device is in neuroscience research, clinical diagnostics and therapeutics applications in the brain, however, the device may also be beneficially applied to other organs and biological systems. Human clinical applications may include neurosurgical intra-operative monitoring, extra-operative chronic monitoring of devices introduced in an operation, and diagnostic monitoring combined with simultaneous neuroimaging. | 09-23-2010 |
| 20100241101 | METHOD AND A BLOOD OXYGEN TESTER FOR DETECTING THE ARTERIAL OR VENOUS BLOOD - A method and a blood oxygen tester for determining whether a blood sample is arterial or venous blood are disclosed. A blood oxygen tester for determining whether a blood sample is arterial or venous blood comprises a housing and a blood sample receptacle defined by the housing. A blood oxygen sensor is in communication with the blood sample receptacle and a test result indicator is in communication with the blood oxygen sensor. The indicator is responsive to the blood oxygen sensor for indicating whether a tested blood sample is arterial blood or venous blood. | 09-23-2010 |
| 20100274217 | Fluid replacement device - A fluid replacement device and method. A console includes a weighing subsystem responsive to a first fluid source and a urine collection chamber. A pump is configured to infuse fluid from the first fluid source into a patient. A processing subsystem in the console is responsive to the weighing subsystem. Based on the weight of the first fluid source and the weight of the urine collection chamber, the patient's urine output and the amount of fluid infused into the patient from the first fluid source are determined. A user interface in the console allows the user to set a desired fluid balance for the patient and the amount of at least one additional fluid delivered to the patient. An actual fluid balance is calculated based on the determined urine output, the determined amount of fluid infused into the patient from the first fluid source, and the set amount of the at least one additional fluid delivered to the patient. The pump is controlled based on the actual fluid balance and the set desired fluid balance so the actual fluid balance becomes the same as or approximately the same as the desired fluid balance. | 10-28-2010 |
| 20100286652 | TECHNIQUES FOR DELIVERY OF STEM CELL AND RELATED THERAPIES TO TREAT CARDIAC CONDITIONS - An exemplary method includes acquiring cardiac electrical activity information; detecting cardiac events within the information including T waves, QRS complexes and/or P waves; and calling for delivery of matter to the heart during a period of time based on the cardiac events. The delivery may occur between a detected T wave and its immediately subsequent QRS complex. The matter being delivered may include stem cells, progenitor cells, nutrients and/or drugs. | 11-11-2010 |
| 20100331813 | Intravascular Cerebral Catheter Device and Method of Use - Cerebral Catheter devices and methods for use are provided. The catheter devices provided may include an anti-thrombotic agent coating on the exterior surface. The catheter devices may include unique tip configurations to allow improved fluid delivery capabilities. Further, the catheter devices may also or alternatively include one or more sensor devices in communication with a controller that allow automatically adjusting the delivery of a therapeutic fluid, for example a vasodilator, in response to the condition sensed by the catheter device, such as increased pressure. Moreover, the catheter devices may also be used in conjunction with blood flow transducers to detect and timely prevent and treatment vasospasms or other conditions. Methods for preventing and treatment vasospasm, neoplasm, or other pathological conditions while prolonged using the catheter device are also provided. | 12-30-2010 |
| 20110054439 | Bolus Dose Determination For A Therapeutic Fluid Dispensing System - Disclosed is a medical device to treat diabetes. The medical device includes a bolus calculator to determine an insulin bolus based on, at least in part, a glycemic index value associated with an intake to be consumed by a user, the bolus calculator further adapted to determine the insulin bolus using one or more inputs selected from the group consisting of carbohydrate load of the intake, current glucose level of the user, residual insulin of the user, carbohydrate to insulin ratio, insulin sensitivity of the user and target glucose level of the user. The bolus calculator is housed in one or more of, for example, an insulin dispensing pump, a handheld remote control unit for an insulin dispensing pump and/or a handheld glucose monitor. | 03-03-2011 |
| 20110077616 | METHODS FOR GUIDING HEART FAILURE DECOMPENSATION THERAPY - An implantable medical device system and associated method for use in guiding an acute decompensated heart failure therapy set an optimal fluid status measurement level. A physiological sensor signal sensed by an implantable medical device is used to compute the fluid status measurement. A target rate of change of the fluid status measurement is computed for guiding the therapy. | 03-31-2011 |
| 20110082440 | METHOD AND SYSTEM FOR DELIVERING ANALGESIC DRUGS - A method and system for delivering analgesic drug is disclosed herein. The method comprises: administering analgesic drug to a patient based on input from a patient controlled input device and continuously measuring pain level of a patient with reference to at least one patient parameter. The method further comprises: receiving drug demand from patient through the patient controlled input device and controlling administration of analgesic drug based on the measured pain level and the received drug demand. | 04-07-2011 |
| 20110092950 | Metronomic Convection Enhanced Delivery of Intrathecal Chemotherapy Using an Implanted Magnetic Breather Pump (MBP) for Leptomeningeal Carcinomatosis - A magnetically controlled pump is implanted into the cerebrospinal fluid of a patient and delivers a plurality of medicating agents at a controlled rate corresponding to the specific needs of the patient. The current invention comprises a flexible double walled lumen, intratumoral catheter which will be implanted. Spinal fluid drawn from the patient is analyzed. Medication is delivered on a continuous metronomic basis into the CSF via an internalized pump. CSF is removed and analyzed for VEGF and other cytokines via spectrophotometer analysis or a lab on a chip. The operation of the apparatus and hence the treatment is remotely controlled based on these measurements and displayed through an external controller. | 04-21-2011 |
| 20110118698 | Device, system, and method for targeted delivery of anti-inflammatory medicaments to a mammalian subject - A device, a system, or a method is described for treating a disease or a condition of one or more joints of articulating bone in a mammalian subject. The device provides one or more medicaments to one or more joints of the mammalian subject. A device is described that includes one or more sheaths configured to contact one or more body contours in proximity to one or more joints of articulating bone of a mammalian subject; one or more sensors configured to detect one or more physiological conditions of the one or more joints; and one or more applicators supported by the one or more sheaths and configured to respond to the one or more sensors by injecting one or more medicaments to the one or more joint tissues of the mammalian subject. | 05-19-2011 |
| 20110152829 | Patient Fluid Management System - A patient fluid care system that provides an integrated solution for managing patient fluids by precisely controlling one or more infusion pumps; monitoring real-time patient sensors, and pharmaceutical information; and deriving patient status and the status of pharmaceuticals administer to the patient based upon such monitoring and controlling; and automatically adjusting infusing parameters based upon the real-time patient, infusion, and pharmaceuticals information and derived patient status and the pharmaceuticals levels. | 06-23-2011 |
| 20110184379 | METHOD AND SYSTEM TO DEFINE PATIENT SPECIFIC THERAPEUTIC REGIMENS BY MEANS OF PHARMACOKINETIC AND PHARMACODYNAMIC TOOLS - Methods for treating Hepatitis infections are provided. In one embodiment, an initial dosage of interferon is administered to a patient, and interferon serum levels and viral load data is collected over time. This data can be used to determine patient-specific pharmacokinetic and pharmacodynamic parameters and then construct patient-specific interferon delivery profiles. Patient-specific delivery profiles can then be used to design patient-specific therapeutic regimens. | 07-28-2011 |
| 20110208155 | CLOSED-LOOP GLUCOSE CONTROL STARTUP - Disclosed are methods, systems, etc. for closed-loop glucose control startup. In certain example embodiments, a request for entry of an automatic mode of operation of a glucose monitoring and insulin delivery system for a patient may be detected. An entry of the automatic mode of operation may be controlled based, at least in part, on a detected rate of change of blood glucose concentration of the patient. In certain other example embodiments, initiation of a continual phase of an automatic mode of operation may be controlled based, at least in part, on a time since a most recent manual delivery of a bolus, on a detected rate of change of blood glucose concentration, on a targeted fixed set point, a combination thereof, and so forth. | 08-25-2011 |
| 20110213331 | APPARATUS FOR CONTROLLING DRUG INFUSION AND METHOD USING THE SAME - A drug infusion control apparatus and method that can improve precision of experiments and thus improve reliability of data obtained from experiments on experimental animals by automatically calculating an infusion amount of a drug in accordance with weights of the experimental animals included in a variety of experimental groups and infusing the calculated amount of the drug into the experimental animals are provided. The drug infusion control method includes calculating and storing a drug infusion amount using weight data of experimental animals according to a preset formula, loading data on the drug infusion amount data that is stored, determining an operation time of an opening/closing valve, receiving an operation signal from an infusion switch, opening the opening/closing valve for a predetermined time, and repeatedly infusing a drug in response to the loaded data by a preset value. | 09-01-2011 |
| 20110213332 | MEDICATION DELIVERY SYSTEM - Some embodiments of a medication delivery system provides for the recommendation or delivery of an amount of medication to a patient based on physiological parameter information and a set or rules. Some embodiments provide for systems and methods of medication delivery based on physiological parameters of, a patient, such as blood glucose level, blood pressure, and the like. | 09-01-2011 |
| 20110230857 | ELECTRONIC DELIVERY SYSTEMS AND METHODS WITH FEEDBACK - In accordance with some embodiments of the present invention, delivery systems and methods for delivering a substance in a medium is provided. The delivery system may include a delivery component, an electronic controller, one or more sensors, and a feedback mechanism. The delivery component has at least one reservoir that contains a substance (e.g., a liquid, a drug, etc.). The electronic controller is connected to the delivery component and controls the release of the substance from the at least one reservoir into the medium. The sensors monitor one or more parameters in the medium and provide a signal to a feedback mechanism. The feedback mechanism, in response to the signal, sends an electrical signal that directs the controller to release the substance from the reservoir into the medium, thereby maintaining a desire level of a monitored parameter (e.g., pH, pO | 09-22-2011 |
| 20110251583 | MEDICAL DEVICE CONFIGURATION BASED ON SENSED BRAIN SIGNALS - The invention is directed to techniques and systems in which external brain monitoring is used to facilitate implantation and configuration of an implantable medical device. The techniques may create an open loop or closed loop system in which brain signals quantify the efficacy of electrical logical stimulation (or drug therapy via an implantable drug pump) at locations outside of the brain. The techniques may be used to improve placement of leads and electrodes during an implantation procedure, and/or to select or adjust stimulation parameters either during the implantation procedure or possibly following implantation of an implantable medical device. The described techniques have applications for the alleviation of pain, but may find other applications where EEG signals can quantify the efficacy of treatment via an implantable medical device. | 10-13-2011 |
| 20110257626 | CONTROLLED NEEDLE-FREE TRANSPORT - A needle-free transdermal transport device for transferring a substance across a surface of a biological body includes a reservoir for storing the substance, a nozzle in fluid communication with the reservoir and a controllable electromagnetic actuator in communication with the reservoir. The actuator, referred to as a Lorentz force actuator, includes a stationary magnet assembly and a moving coil assembly. The coil assembly moves a piston having an end portion positioned within the reservoir. The actuator receives an electrical input and generates in response a corresponding force acting on the piston and causing a needle-free transfer of the substance between the reservoir and the biological body. The magnitude, direction and duration of the force are dynamically controlled (e.g., servo-controlled) by the electrical input and can be altered during the course of an actuation cycle. Beneficially, the actuator can be moved in different directions according to the electrical input. | 10-20-2011 |
| 20110288524 | Patient hydration method - A patient hydration method includes administering hydration fluid to a patient, and a hydration fluid measurement device responsible to a source of hydration fluid, a patient urine output measurement device. A controller is responsive to the hydration fluid measurement device and the patient urine output measurement device. The controller operates the infusion device, in response to the patient urine output measurement device and the hydration fluid measurement device, to hydrate the patient based on the patient's urine output. | 11-24-2011 |
| 20110301568 | Systems and Methods to Treat Cardiac Pacing Conditions - The method may include administering to a subject in need thereof an effective amount of an HCN polynucleotide. The HCN polynucleotide includes a nucleotide sequence encoding an HCN polypeptide having channel activity. The amino acid sequence of the HCN polypeptide and the amino acid sequence of a reference polypeptide have at least 80% identity, where the reference polypeptide begins with an amino acid selected from amino acids 92-214 and ends with an amino acid selected from amino acids 723-1188 of SEQ ID NO:8. An example of a reference polypeptide is amino acids 214-723 of SEQ ID NO:8. The HCN polynucleotide may be DNA or RNA. | 12-08-2011 |
| 20110301569 | Methods and apparatus for the CVCS - The present invention provides an indirect method and accompanying apparatus for supplying a high concentration of medicaments, particularly antibiotics, to the nasal sinuses by first loading the medicament into the cerebrospinal venous system (CVCS) via a Valsalva manuever. Because the CVCS is a valveless, three-dimensional closed system, traditional physiological dogma such as veins always draining tissues does not always apply. Instead, because in its closed-system blood can flow in any direction, the blood of the CVCS and any medicaments that it contains will be drawn to any portion of it where there is increased outflow, such as the copious venous-derived sinus fluid drainage present during nasal allergy or nasal infection. Thus, the very nasal congestion that impedes the effectiveness of direct medicament application, such as seen with nasal inhalers or systemic antibiotics, aids in applying the medicament indirectly to the nasal sinuses via the CVCS. Additionally, the present method has the benefit of delivering medicaments that, unlike present treatment regimens, are not limited solely to those medicaments that can be successfully absorbed from the G.I. tract. This means that, in the case of antibiotics, the bacteria infecting this portion of the CVCS will not be as resistant to treatment if they have not had prior exposure to this new line of antibiotics. Finally, if the infection extends to the eardrums, making the Valsalva maneuver painful, or if the patient is simply unusually sensitive, then earplugs to reduce the stress on the eardrums may be worn while the patient performs the Valsalva maneuver. | 12-08-2011 |
| 20120010590 | Swallowable Drug Delivery Device and Method of Delivery - Embodiments of the invention provide swallowable devices, preparations and methods for delivering drugs and other therapeutic agents within the GI tract. Some embodiments provide a swallowable device such as a capsule for delivering drugs into the intestinal wall or other GI lumen. The device comprises a capsule sized to be swallowed and pass through the intestinal tract. The capsule can include at least one guide tube, one or more tissue penetrating members positioned in the guide tube, a delivery member, an actuating mechanism and a release element. The release element degrades upon exposure to various conditions in the intestine so as to release and actuate the actuating mechanism. Embodiments of the invention are particularly useful for the delivery of drugs which are poorly absorbed, tolerated and/or degraded within the GI tract. | 01-12-2012 |
| 20120010591 | SYSTEM FOR CONTROLLING MEANS FOR INJECTION OF ANAESTHETICS OR SEDATIVES WITH A VIEW TO INDUCING ANAESTHESIA OR SEDATION - This system is characterized in that it includes means ( | 01-12-2012 |
| 20120035583 | MULTIMODE NEUROBIOPHYSIOLOGY PROBE - Deep Brain Stimulation (DBS) is taking off and will be part of the main treatment for brain diseases such as movement disorders, epilepsy, psychiatric diseases and many others. There is a need for more sophisticated devices that can do more in one penetration, not just stimulate. Once there is a probe in the brain, it is used for multiple passive measurements, without harming the brain further. It provides better understanding the brain and real time closed loop improved treatment. An apparatus and method are disclosed, which allow simultaneous monitoring of multiple parameters inside the human brain, such as: pH, temperature, pressure, seizure activity (EEG), degree of metabolism, oxygen tension in the brain, degree of excitotoxicity and others. The ability to measure those parameters during treatment and stimulation procedures makes the difference between success and failure of the patient. | 02-09-2012 |
| 20120046641 | METHODS OF DIAGNOSING AND TREATING DYSPHAGIA - Methods for evaluating and treating patients for dysphagia are provided. In a general embodiment, the method comprises screening the patient for dysphagia symptoms, diagnosing and categorizing the dysphagia if the patient exceeds a threshold of dysphagia symptoms, choosing the proper dysphagia treatment product based the patient's dysphagia, and giving the patient preparation instructions for the dysphagia treatment product. | 02-23-2012 |
| 20120046642 | OPTICAL DETECTOR FOR USE IN THERAPY - Activation of an enzyme in a bodily fluid is detected based on the amount of cleavage of a substrate for the enzyme. The substrate is tagged with two fluorescent dyes—a donor and an acceptor. The tagged substrate is presented to the bodily fluid. A device emits energy at a first wavelength into the bodily fluid, and detects energy at second and third wavelengths emitted by the dyes in response to the energy at the first wavelength. Prior to enzymatic cleavage of the substrate, the acceptor emits energy at the third wavelength in response to energy at the second wavelength received through fluorescent resonant energy transfer (FRET) from the donor. After enzymatic cleavage of the substrate, the donor emits energy at the second wavelength. The device can determine the concentration of activated enzyme within the bodily fluid based on the relative intensities of energy at the second and third wavelengths. | 02-23-2012 |
| 20120059351 | APPARATUS AND METHOD FOR MEDICATION DELIVERY USING SINGLE INPUT-SINGLE OUTPUT (SISO) MODEL PREDICTIVE CONTROL - A method includes receiving measurements from a sensor associated with a patient at a portable medication delivery device. The method also includes controlling delivery of medication to the patient at the portable medication delivery device using a single input, single output (SISO) model predictive control technique. The SISO model predictive control technique includes predicting a characteristic of the patient using the measurements and a model associated with the patient. The SISO model predictive control technique also includes determining whether the characteristic of the patient is predicted to fall outside of a desired range. In addition, the SISO model predictive control technique includes, if the characteristic of the patient is predicted to fall outside of the desired range, determining an amount of medication to deliver to the patient and delivering the determined amount of medication to the patient. | 03-08-2012 |
| 20120059352 | Insulin Delivery Safety - Embodiments of the present disclosure are directed to systems, devices/apparatuses and methods for assessing a residual insulin value for a user/patient. Such embodiments may be implemented by selecting a first value corresponding to a duration of insulin action; selecting a second value corresponding to a lock out time duration, selecting a first time period beginning at a time point T | 03-08-2012 |
| 20120065617 | SYSTEMS AND METHODS FOR INTRAVENOUS DRUG MANAGEMENT USING IMMITTANCE SPECTROSCOPY - Described herein are devices, systems, and methods for determining the composition of liquids, including the identity of one or more drugs in the liquid, the concentration of the drug, and the type of diluent using immittance spectroscopy. These devices, systems and methods are particularly useful for describing the identity and, in some variations, concentration of one or more components of a medical liquid such as intravenous fluid. In particular, described herein are devices, systems and methods that may operate in low ionic strength diluents. Also described are methods of recognizing complex immittance spectrograph patterns to determine the composition of a liquid by pattern recognition. | 03-15-2012 |
| 20120078221 | METHODS AND SYSTEMS FOR ADJUSTING AN INSULIN DELIVERY PROFILE OF AN INSULIN PUMP - Systems and methods are disclosed for adjusting the delivery times of an insulin delivery profile of an insulin pump, wherein the insulin pump is operable to automatically deliver insulin to a person having diabetes based on an operating time of the internal clock and a delivery time of an insulin delivery profile. The method may comprise receiving a local time zone time from an external local clock, determining whether the operating time of the internal clock differs from the local time zone time by at least a first predetermined amount of time, requesting the person provide a time adjustment value when the operating time of the internal clock differs from the local time zone time by at least the first predetermined amount of time, receiving the time adjustment value from the person, and adjusting the delivery times of the insulin delivery profile based on the time adjustment value when received. | 03-29-2012 |
| 20120089115 | Reduction of Recirculation in Catheters - A catheter tip designed to reduce the outflow velocity and/or directional momentum of fluid being infused by a catheter having such a tip. In one variation, a plurality of channels is provided at the distal portion of the catheter to increase the outflow cross-sectional area. In another variation, the diameter of the catheter at its distal portion where the fluid exits is increased. In yet another variation, a bullet-shaped nose is implemented which may decrease turbulence at the distal end of catheter tip. The low velocity outflow catheter tip may also be implemented on a dual lumen catheter, such as a hemodialysis catheter, to reduce recirculation rate. Various device configurations and methods for such implementations are also disclosed. | 04-12-2012 |
| 20120095437 | AUTOMATIC CONTROL SYSTEM AND METHOD FOR THE CONTROL OF ANESTHESIA - The present invention relates to an automatic anesthesia control system and method for the detection of the degree of each component of general anesthesia, automatic detection of drugs administered and automatic drug delivery via intravenous route. | 04-19-2012 |
| 20120101473 | Decision-Assist Method of Resuscitation of Patients - A method for providing decision-assist to medical staff resuscitating a burn patient includes receiving patient information, calculating an infusion rate, outputting the infusion rate, obtaining a urinary output, calculating a new infusion rate using infusion rate model based constants, and outputting the new infusion rate. In some embodiments, the method includes notifying medical staff when problems arise, displaying information regarding the resuscitation, and setting limits regarding the infusion rates. | 04-26-2012 |
| 20120136335 | FOCAL MEDICATION TITRATION SYSTEM - A system is provided for implantation into the skull of a patient including a device to detect the onset and/or existence of a neurological condition and deliver a medication to prevent the neurological condition, and/or to improve or sustain normal neurological function. Methods for utilizing the system and device are also provided. | 05-31-2012 |
| 20120157963 | METHOD FOR THE DETECTION AND TREATMENT OF ABERRANT NEURAL-ELECTRIC ACTIVITY - An apparatus for detection of ANEA comprising an introducer having at least one lumen. The introducer is introduced into brain tissue through an opening in the skull. A reference electrode is positioned at an introducer distal portion. A plurality of electrode members are advanceable within the at least one lumen with each member having an insulated portion and an exposed distal portion. The members have a non-deployed state in the introducer and a deployed state when outwardly advanced out of the introducer. In the deployed state, the members are substantially orthogonal to each other with the exposed distal portions defining a detection volume capable of determining an electric field vector produced by the ANEA and the direction of foci of the ANEA. | 06-21-2012 |
| 20120172833 | SYSTEM AND METHOD FOR CONTROLLING DRUG DELIVERY - The present invention relates to a system for delivering a drug to a patient, which comprises at least one electro-physical sensor, a control unit and a drug-delivery device adapted to contain at least one drug to be delivered to such patient. The sensor and control unit are capable of determining a physiological state in a patient wearing the sensor, and the control unit is capable of issuing instructions to the drug-delivery device so as to deliver the drug to the patient at a flow-rate which is a function of the physiological state determined. | 07-05-2012 |
| 20120179135 | SYSTEM AND METHOD FOR CLOSED-LOOP PATIENT-ADAPTIVE HEMODYNAMIC MANAGEMENT - A system and method for patient-adaptive hemodynamic management is described. One embodiment includes a system for hemodynamic management including transfusion, volume resuscitation with intravenous fluids, and medications, utilizing monitored hemodynamic parameters including the described dynamic predictors of fluid responsiveness, and including an intelligent algorithm capable of adaptation of the function of the device to specific patients. | 07-12-2012 |
| 20120179136 | SYSTEM AND METHOD FOR CLOSED-LOOP PATIENT-ADAPTIVE HEMODYNAMIC MANAGEMENT - A system and method for patient-adaptive hemodynamic management is described. One embodiment includes a system for hemodynamic management including transfusion, volume resuscitation with intravenous fluids, and medications, utilizing monitored hemodynamic parameters including the described dynamic predictors of fluid responsiveness, and including an intelligent algorithm capable of adaptation of the function of the device to specific patients. | 07-12-2012 |
| 20120191061 | DEVICES AND METHODS FOR ADJUSTING BASAL DELIVERY PROFILE - The present disclosure presents systems, devices and methods for administration of a therapeutic fluid to the body of a patient at a transient basal delivery profile, and enabling modification of the transient profile. Some embodiments include a user interface enabling input of one or more transient basal related parameters, and a processor having a basal programming application operating thereon. The basal programming application configured for determining a transient basal profile based on at least one or more transient basal related parameters. The transient basal profile comprises a plurality of phases and wherein each of the plurality of phases is characterized by a duration and at least one basal rate. In some embodiments, at least one of the plurality of phases includes either a basal overshot or a basal undershot. Some embodiments may also include a pump for dispensing the therapeutic fluid from a reservoir to the body of the patient. | 07-26-2012 |
| 20120197231 | IMPLANTABLE MEDICAL DEVICE WITH CHEMICAL SENSOR AND RELATED METHODS - In an embodiment, the invention includes an implantable medical device with a pulse generator and a chemical sensor in communication with the pulse generator, the chemical sensor configured to detect an ion concentration in a bodily fluid. In an embodiment, the invention includes a method for providing cardiac arrhythmia therapy to a patient including sensing a physiological concentration of an analyte, communicating data regarding the physiological concentration of the analyte to an implanted pulse generator, and delivering therapy to the patient based in part on the physiological concentration of the ion. In an embodiment, the invention includes a method for monitoring diuretic therapy. In an embodiment, the invention includes a method for controlling delivery of an active agent into a human body. Other aspects and embodiments are provided herein. | 08-02-2012 |
| 20120232518 | DETACHABLE PORTABLE INFUSION DEVICE - A portable therapeutic apparatus and a method for controlling the apparatus are provided. In one aspect the apparatus and the method can be implemented using a patch unit ( | 09-13-2012 |
| 20120277722 | ADAPTIVE SYSTEM FOR BLOOD FLUID REMOVAL - Methods for monitoring patient parameters and blood fluid removal system parameters include identifying those system parameters that result in improved patient parameters or in worsened patient parameters. By comparing the patient's past responses to system parameters or changes in system parameters, a blood fluid removal system may be able to avoid future use of parameters that may harm the patient and may be able to learn which parameters are likely to be most effective in treating the patient in a blood fluid removal session. | 11-01-2012 |
| 20120302990 | CORE APPARATUS CONNECTABLE TO A VARIETY OF SENSORS, FLUID DELIVERY DEVICES AND OTHER DEVICES TO FORM A SYSTEM, SUCH AS FOR DIABETES MANAGEMENT SYSTEM - A core apparatus connectable to at least one sensor and to at least one fluid delivery device which includes a base housing, a connection hub to couple to the at least one sensor and to the at least one fluid delivery device, and a controller disposed within the base housing to communicate with the at least one sensor and to the at least one fluid delivery device, wherein the controller forms a continuous feedback loop with the at least one sensor and the at least one fluid delivery device. | 11-29-2012 |
| 20120323215 | System and method for administering medicaments on the basis of urine values - The invention relates to a system and a method for administering medicaments to a patient, comprising: at least a first measuring device ( | 12-20-2012 |
| 20120330274 | Device, system, and method including micro-patterned cell treatment array - Devices, systems, or methods are disclosed herein for treatment of disease in a vertebrate subject. The device can include a quasi-planar substrate; and one or more laterally-mobile effector molecule types at least partially embedded within the quasi-planar substrate, wherein the one or more laterally-mobile effector molecule types is configured to interact with one or more cell types. The device can further include one or more sensors configured to detect at least one aspect of an interaction between the at least one of the one or more laterally-mobile effector molecule types and the one or more cell types; and a controller in communication with the one or more sensors, wherein the controller is configured to responsively initiate modification of at least one of the one or more laterally-mobile effector molecule types, the quasi-planar substrate, and the one or more cell types. | 12-27-2012 |
| 20130046279 | USER INTERFACE FEATURE FOR DRUG DELIVERY SYSTEM - A medical system includes a monitoring unit and a drug delivery unit. The monitoring unit is operable to monitor at least one physiological parameter of a patient. The drug delivery unit includes an integral volume of a drug. A control logic is in communication with the monitoring unit and the drug delivery unit and is operable to regulate delivery of the drug to the patient from the integral volume, based on data associated with the at least one physiological parameter of the patient, in accordance with a safety shell control algorithm. A user interface feature is operable to receive input indicating administration of an external drug to the patient. The safety shell control algorithm responds to inputs received through the user interface feature indicating administration of an external drug to the patient, such as by modifying subsequent drug delivery regulation based on the administration of the external drug. | 02-21-2013 |
| 20130046280 | DRUG DELIVERY SYSTEM WITH PROCEDURE STAGE BASED DELIVERY ADJUSTMENT - A medical system includes a monitoring unit and a drug delivery unit. The monitoring unit is operable to monitor at least one physiological parameter of a patient. The drug delivery unit includes an integral volume of a drug. A control logic is in communication with the monitoring unit and is operable to regulate delivery of the drug to the patient from the integral volume, based on data associated with the at least one physiological parameter of the patient, in accordance with a safety shell control algorithm. A user interface feature is operable to receive input indicating a stage of progress in a medical procedure. The safety shell control algorithm responds to inputs received through the user interface feature indicating a stage of progress in a medical procedure, such as by modifying subsequent drug delivery regulation based on the beginning or completion of a stage of progress in a medical procedure. | 02-21-2013 |
| 20130060228 | Secure Perfusion System - The invention relates to a secure system for the perfusion of a body liquid, enabling a final control of compatability of a treatment with the patient and/or the medical situation previously diagnosed by a doctor, in a simple, efficient and energy-saving manner. To this end, the system according to the invention comprises: a fluidic circuit of a perfusion ( | 03-07-2013 |
| 20130085471 | System and Method for Monitoring Time Intervals During Blood Parameter Monitoring - A system and method for monitoring at least one blood parameter of the blood of different patients, comprising a plurality of access devices for establishing at least one means of access to the blood of each patient through the skin, a plurality of removal devices for removing a quantity of blood from each patient in order to obtain at least one blood sample, at least one blood analysis device for analysing the blood sample with respect to predeterminable blood parameters and for generating individual blood parameter data sets, a calculation device which can be used jointly for a plurality of blood parameter data sets of different patients for calculating data sets of drug parameters of the drugs to be administered to the respective patient on the basis of the individual blood parameter data sets, and a plurality of supply devices for supplying the respective drug having the calculated drug parameters. | 04-04-2013 |
| 20130123745 | INFUSION PUMP INCLUDING PAIN CONTROLLED ANALGESIC ("PCA") APPARATUS - An infusion pump includes: a housing, a pump actuator supported by the housing, electronics configured to control the pump actuator, a pain controlled analgesic (“PCA”) input device, a cord having a remote end connected to the PCA input device and a local end connected to the housing, a remote integrated circuit; and a local integrated circuit in communication with the electronics and the remote integrated circuit so as to provide operational information concerning the PCA input device to the electronics. | 05-16-2013 |
| 20130150823 | METHOD AND APPARATUS FOR PROVIDING HYDRATION FLUID - The invention relates to a method and apparatus for providing hydration fluids. The invention allows for a ‘background’ rate of providing a hydration fluid to be automatically supplied by an apparatus to a patient, for example intravenously, and for the patient to receive an extra amount of hydration fluid, or ‘bolus dose’, to be provided when the patient sends a signal to the apparatus. In preferred embodiments the background supply rate, the volume and rate of supply of the bolus dose and the maximum extra volume that can be provided as bolus doses in a given time can be set, for example, by a nurse. | 06-13-2013 |
| 20130150824 | Infusion Pump Systems and Methods - Some embodiments of an infusion pump system can include a controller in which one or more features sets to be provided by the controller are enabled or disabled based upon the particular pump device that is connected to the controller. For example, in some embodiments, one or more advanced features of the controller are available to the user only when a first type of pump device (e.g., having predefined settings stored therein) is connected to the controller, and those advanced features of the controller are disabled when a second type of pump device is connected to the controller. | 06-13-2013 |
| 20130172849 | System and Method for Providing Servo-Controlled Resuscitation - The present invention provides a system and method for controlling resuscitation in a patient. In at least one embodiment, the invention includes a fluid rate measurer, a controller electrically coupled to the fluid rate measurer, and a pump. The controller is adapted to receive signals from a physiological monitor and controls the pump. | 07-04-2013 |
| 20130211372 | Body Cavity Physiological Measurement Device - Provided herein is a self-contained physiological measuring device adapted for disposition within a patient body cavity, primarily the vagina, for an extended period of time (e.g., 6-48 hours or more). While disposed within the body cavity, the device periodically measures one or more physiological parameters. In addition to measuring such physiological parameters, the device is operative to store such measurements to memory for subsequent download/processing upon removal of the device from the body cavity and/or upon wireless interrogation. | 08-15-2013 |
| 20130226137 | METHOD AND APPARATUS FOR SYRINGE INJECTION OF FLUIDS - A system for delivering or withdrawing a fluid to or from the body of a patient in a manner that permits delivery to be controlled based upon feedback from the patient, the system including a syringe assembly providing a syringe operably coupled to one or more sensors adapted to determine one or more corresponding parameters associated with fluid delivery and/or withdrawal, and a monitor adapted to be communicably associated with the one or more sensors of the syringe assembly, and optionally with other sensors or inputs providing additional parameters as well, the monitor comprising one or more read out mechanisms either directly or indirectly corresponding to the one or more fluid delivery/withdrawal parameters, and optionally with one or more of the additional parameters as well. | 08-29-2013 |
| 20130245599 | FLUID MANAGEMENT SYSTEM - Fluid management systems and methods of operating fluid management systems which may provide one or more functions associated with suction, irrigation, distention, deficit monitoring, infusion, fluid warming, and the like. Some example embodiments may include infra-red lamps arranged to heat fluid flowing through a disposable cartridge. Some example embodiments may provide a three-dimensional fluid path through the cartridge and/or multi-stage heating capabilities. Some example fluid management systems may be selectable between pressure control and flow control modes. | 09-19-2013 |
| 20130281969 | CONTROLLED RELEASE NANOPARTICULATE MATTER DELIVERY SYSTEM - A controlled release nanoparticulate matter delivery system includes a plurality of thermoresponsive modules containing a respective nanoparticulate matter. Each thermoresponsive module is selectively operable in at least one of a heating mode that releases the nanoparticulate matter and a cooling mode that inhibits release of the nanoparticulate matter. A control module is in electrical communication with the plurality of thermoresponsive modules. The control module is configured to determine a temperature of each thermoresponsive module and to select the at least one heating mode and cooling mode based on the temperature. The heating and cooling mode may be selected in response to a desired dosing profile and/or a biometric condition. | 10-24-2013 |
| 20130289521 | SYSTEM AND METHOD FOR REGULATING ENDOGENOUS NEUROMODULATORY AGENT LEVELS - One aspect of the present disclosure includes a closed-loop therapy delivery system for regulating an endogenous level of a first neuromodulatory agent in a subject. The therapy delivery system includes a sensing component, a delivery component, and a controller. The sensing component is configured to detect an extracellular level of the first neuromodulatory agent. The delivery component is configured to deliver an amount of a second neuromodulatory agent to an intraparenchymal target site of the subject. The controller is configured to coordinate operation of the sensing component and the delivery component. | 10-31-2013 |
| 20130289522 | Methods and Systems for Closed Loop Neurotrophic Delivery Microsystems - Brain Machine Interfaces (BMIs) promise to improve the lives of many patients by providing a direct communication pathway between the brain and one or more external devices. As the brain is an electrochemical system additional signals may improve BMI performance beyond direct electrical signals. Further many psychiatric and neurological disorders such as Parkinson's disease, depression, dystonia, or obsessive compulsive disorder are related to neurotransmitter deficiencies or imbalances. Accordingly detection of neurotransmitter chemicals and/or management of these chemicals may enhance BMIs. Embodiments of the invention provide for implantable CMOS based target derived neurotrophic factor delivery microsystems and neurochemical sensors allowing neurotransmitter deficiencies or imbalances to be detected, monitored, and corrected. Such implantable CMOS solutions provide for high volume, low cost manufacturing as well integration options in arrayed formats as well as integration with other CMOS electronic circuits. | 10-31-2013 |
| 20130296823 | Intelligent Drug and/or Fluid Delivery System to Optimizing Medical Treatment or Therapy Using Pharmacodynamic and/or Pharamacokinetic Data - A pharmacodynamic (PD), pharmacokinetic (PK), or both and PK guided infusion device, system and method optimizes the safety and efficacy of various forms of treatment or therapy (e.g., drug and/or fluid) in a variety of health-care and other settings. | 11-07-2013 |
| 20130338628 | Probablistic Pharmacokinetic and Pharmacodynamic Modeling - The subject matter disclosed herein provides a response to a dose of a substance and/or controls the administration of the dose. In one aspect, there is provided a system. The system may include a processor and at least one memory configured to provide a response determinator. The response determinator may receive therapeutic and wellness data. Moreover, the response determinator may determine a response based on the received therapeutic and wellness data. The response may represent a reaction to a substance integrated with an ingestible event marker. The determined response may be provided to, for example, a therapy controller. Related systems, methods, and articles of manufacture are also described. | 12-19-2013 |
| 20130345662 | MEDICAL FLUID DELIVERY SYSTEM - A medical fluid delivery system is provided including a steerable, guide catheter, a delivery catheter adapted for deployment at a targeted tissue site using the steerable guide catheter, the delivery catheter including a proximal port, a distal port, and a lumen extending between the proximal and distal ports; a distal fixation element coupled to the delivery catheter so as to position the distal port adjacent the targeted tissue site; and a flexible hollow needle adapted to be advanced through the delivery catheter lumen, the flexible needle including a tissue-piercing distal tip for extending from the distal port of the delivery catheter for advancement into the targeted tissue site and a proximal end for extending from the proximal port of the delivery catheter through which a medical fluid is delivered. | 12-26-2013 |
| 20130345663 | DIABETES THERAPY MANAGEMENT SYSTEM FOR RECOMMENDING BOLUS CALCULATOR ADJUSTMENTS - A method of managing use of an insulin infusion device is presented here. The method identifies bolus calculator event data from glucose data for a user of the infusion device. The bolus calculator event data corresponds to use of a bolus calculator that calculates bolus dosage recommendations based on a user entered carbohydrate consumption value, a user entered current blood glucose value, a user specific carbohydrate ratio value, and a user specific insulin sensitivity value. The method filters the bolus calculator event data to remove glucose data associated with certain conditions, and analyzes the filtered data to detect an event occurrence that is indicative of potential maladjustment of the carbohydrate ratio value or the insulin sensitivity value. The method outputs a recommendation to adjust the carbohydrate ratio value or the insulin sensitivity value, based on characteristics of the detected event occurrence. | 12-26-2013 |
| 20140012225 | DELIVERY SYSTEM - Provided herein is a delivery system, including: (a) an optical sensor configured to detect data to create a map of a patient bodily surface; and (b) a dispenser operatively associated with the optical sensor and configured to deliver compositions (optionally including cells) to the patient bodily surface based upon the data or map. Methods of forming a tissue on a patient bodily surface of a patient in need thereof are also provided, as are methods, systems and computer program products useful for processing patient bodily surface data. | 01-09-2014 |
| 20140018768 | SENSOR - The invention relates to an electronic sensor for detecting skin, the sensor comprising processor, an EM source, a baffle, a first EM detector and a second EM detector, the sensor arranged such that the EM source is located on a first side of the baffle and the first and second EM detectors are arranged on a second opposite side of the baffle at first and second distances from the EM source respectively, the first distance being less than the second distance, the processor configured to cause the source to emit EM radiation and to receive first and second signals from the first and second EM detectors respectively, the signals being indicative of the intensity of EM radiation detected by the sensor, the processor being further configured to process the first and second signals and thereby generate a skin signal which is indicative of whether the sensor has detected skin. | 01-16-2014 |
| 20140025034 | RESUSCITATION DEVICE AND METHOD FOR RESUSCITATION - A method for providing a resuscitating treatment of a human being, which has the following actions sensing human muscle activity, human breathing activity, human neural activity or human cerebral activity, determining whether the human being is in a state of developing apnoea by a processing unit based on the sensing, provoking an induced aspiration reflex by a resuscitating stimulation of a respiratory area of a human brain stem by providing a stimulus with a stimulation device to a location distant from the respiratory area of the human brain stem upon the processing unit determining the state of developing apnoea, the location being a nasal filter of the human being or a nasopharyngeal area of the human being. | 01-23-2014 |
| 20140039450 | Method and Apparatus for Treating Respiratory Disease - A method of influencing bronchoconstriction in a mammal comprising applying a stimulation in one or more regions of the brain of the mammal, and an apparatus therefore. The method and apparatus may be used to treat a respiratory disease or sleep apnea. | 02-06-2014 |
| 20140046291 | VEIN IMAGING SYSTEMS AND METHODS - Some embodiments of this disclosure relates to systems and methods for imaging a patient's vasculature. For example, near infrared (NIR) light can be used to illuminate a target area and light that is reflected or scattered from the target area can be used for generate an image of the target area. In some embodiments, the system can be configured such that the image shows the presence, absence, or extent of infiltration or extravasation in the target area. The system can be configured to document that presence, absence, or extend of infiltration or extravasation at an infusion site. In some embodiments, an imaging system can be mounted onto a patient so that the imaging system can monitor an infusion site, and the imaging system can be configured to automatically detect the presence of infiltration or extravasation. | 02-13-2014 |
| 20140058352 | ENTERAL FEEDING APPARATUS - Embodiments of the present invention include a enteral feeding apparatus and/or system in which an enteral feeding pump can be configured to deliver enteral formula to a patient in accordance with a delivery parameter determined using patient information associated with a patient to be treated and formula information associated with an enteral formula to be delivered to the patient. Exemplary embodiments can determine an estimated daily caloric intake for a patient and can configure the enteral feeding pump to satisfy the caloric requirements of the patient. Exemplary embodiments are also able to monitor the delivery of the enteral formula to ensure that the patient is being properly treated. | 02-27-2014 |
| 20140074059 | METHOD AND SYSTEM TO INDICATE GLYCEMIC IMPACTS OF INSULIN INFUSION PUMP COMMANDS - Various methods and system to provide insight into how certain commands to a patient's infusion pump impact glycemic control of the subject. These patterns help to identify very specific areas of glycemic excursions, enable patients and HCPs to more easily identify patterns of hypoglycemia and hyperglycemia in order to take steps to improve glycemic control of the person with diabetes. | 03-13-2014 |
| 20140074060 | APPARATUS, SYSTEMS AND METHODS FOR THE TREATMENT OF NEUROLOGICAL CONDITIONS - Various embodiments described herein provide an apparatus system, and method for detecting and treating various neurological events or conditions such as epilepsy and migraine headaches which are associated with cortical spreading depression (CSD). Also, many embodiments provide an apparatus, system and method for delivery of a drug such as a loop diuretic to prevent or reduce the duration of a seizure or other event associated with CSD. The drug may delivered intra-cranially in a dose selected to produce a localized effect in the brain to prevent or reduce the duration of the seizure or other event while minimizing adverse peripheral effects such as diuresis or electrolyte loss. | 03-13-2014 |
| 20140081235 | METHOD AND A SYSTEM FOR CONTROLLING DISCOMFORT LEVEL - Present invention relates to a method of controlling the discomfort level experienced by a subject. The method comprises receiving a signal from the subject to initiate comfort relief, determining vital sign data of the subject, determining whether the vital sign data fulfils a predetermined criterion, and performing an infusion regime of infusing a comfort relief drug into the subject based on whether the vital sign data fulfils the predetermined criterion. | 03-20-2014 |
| 20140128837 | SYSTEMS AND METHODS FOR MANAGING GLYCEMIC VARIABILITY - Methods and apparatus, including computer program products, are provided for processing analyte data. In some example implementations, a method may include generating glucose sensor data indicative of a host's glucose concentration using a glucose sensor; calculating a glycemic variability index (GVI) value based on the glucose sensor data; and providing output to a user responsive to the calculated glycemic variability index value. The GVI may be a ratio of a length of a line representative of the sensor data and an ideal length of the line. Related systems, methods, and articles of manufacture are also disclosed. | 05-08-2014 |
| 20140128838 | METHOD FOR SETTING A BLOOD TRANSFUSION PARAMETER - One variation of a method for setting a blood transfusion parameter for a patient includes identifying a blood transfusion bag in a photographic image; extracting a color feature from a region of the photographic image corresponding to the blood transfusion bag; estimating a blood component content within the blood transfusion bag based on the color feature; and triggering transfusion from the blood transfusion bag based on the blood component content within the blood transfusion bag and an estimated volemic status of the patient. | 05-08-2014 |
| 20140142539 | Decision-Assist Method of Resuscitation of Patients - A method for providing decision-assist to medical staff resuscitating a burn patient includes receiving patient information, calculating an infusion rate, outputting the infusion rate, obtaining a urinary output, calculating a new infusion rate using infusion rate model based constants, and outputting the new infusion rate. In some embodiments, the method includes notifying medical staff when problems arise, displaying information regarding the resuscitation, and setting limits regarding the infusion rates. | 05-22-2014 |
| 20140163516 | Fluid Bypass Device for Valved Catheters - Bypass elements for medical valves and methods of using the same are disclosed. Embodiments of the invention include an insert having a tip that is adapted to displace a valve element without penetrating it, and a lumen that fluidly communicates with a lumen of a valve housing distal to the valve element when the bypass element is engaged. Bypass elements are used, in certain embodiments, to facilitate fluid pressure and ECG signal measurements through implanted medical devices including catheters. | 06-12-2014 |
| 20140188072 | SYSTEM AND METHOD FOR CLOSED-LOOP PATIENT-ADAPTIVE HEMODYNAMIC MANAGEMENT - A system and method for patient-adaptive hemodynamic management is described. One embodiment includes a system for hemodynamic management including transfusion, volume resuscitation with intravenous fluids, and medications, utilizing monitored hemodynamic parameters including the described dynamic predictors of fluid responsiveness, and including an intelligent algorithm capable of adaptation of the function of the device to specific patients. | 07-03-2014 |
| 20140200544 | DRUG SUPPLY START TIMING DETERMINATION METHOD AND DRUG CONVEYANCE SYSTEM - The present invention relates to a method for determining start timing of supply of drug to be given in which a peripheral circulatory function and an autonomic nervous function are activated through a stimulus applied to a stimulus application origin part of a body surface by an acupuncture needle or warm heating etc., and a drug conveyance system according to the method for determining start timing of supply of drug. | 07-17-2014 |
| 20140207099 | DEVICE, SYSTEM AND METHOD FOR FACILITATING SYRINGE BASED DRUG DELIVERY AND MANAGEMENT THEREOF - The present invention relates to a device, system and a method for optimizing syringe based drug delivery profile with a treatment element and in particular, to such a device, system and method in which optimization is based on a plurality of data that directly and/or indirectly affect the optimization of the drug delivery profile. The device facilitating syringe based drug delivery, by optimizing drug delivery of the injected drug, records user's activity, and data relative to drug injections, comprising a disposable unit configured for a single use period and a rechargeable reusable unit having electronics comprising a sensor module. | 07-24-2014 |
| 20140221962 | Dynamic Therapy Delivery System - Systems for delivery of therapeutic agents and related methods are disclosed. A sensing system is configured to detect a chemical in the vicinity of a patient and transmit a signal to a controller upon detection. A controller is configured to release a therapeutic agent which is transported to the site of interest. The controller communicates with an electronic medical records database, an alarm and a nurse call system. | 08-07-2014 |
| 20140221963 | USE OF EATING DETECTION TO CONTROL THE RELEASE OF BIOLOGICALLY ACTIVE AGENTS - Systems, apparatuses, and methods for delivery of an active agent in response to the changes in electrical activity of a subject's lower esophageal sphincter. Changes in electrical activity can be monitored by a monitoring unit containing a microprocessor. A reservoir and pump can be used to store and release the active agent. The active agent can be cholecystokinin, peptide YY, glucagon-like peptide 1 or 2, and ghrelin, or a combination thereof. | 08-07-2014 |
| 20140236118 | DEEP VEIN THROMBOSIS THERAPEUTIC METHODS - The invention provides methods for diagnosing and treating deep vein thrombosis and other conditions associated with occluded or constricted vessels. According to certain aspects, methods of the invention involve inserting a sensing device into a vessel having a thrombus therein, assessing, with the sensing device, one or more functional parameters within the vessel, determining an interventional therapy for treating the thrombus based on the assessing step; and performing the interventional therapy. | 08-21-2014 |
| 20140257238 | THERAPEUTIC AGENT PREPARATIONS INTO A LUMEN OF THE INTESTINAL TRACT USING A SWALLOWABLE DRUG DELIVERY DEVICE - Embodiments of the invention provide swallowable devices, preparations and methods for delivering drugs and other therapeutic agents within the GI tract. Many embodiments provide a swallowable device for delivering the agents. Particular embodiments provide a swallowable device such as a capsule for delivering drugs into the intestinal wall or other GI lumen. Embodiments also provide various drug preparations that are configured to be contained within the capsule, advanced from the capsule into the intestinal wall and degrade within the wall to release the drug to produce a therapeutic effect. The preparation can be coupled to an actuator having a first configuration where the preparation is contained in the capsule and a second configuration where the preparation is advanced out of the capsule into the intestinal wall. Embodiments of the invention are particularly useful for the delivery of drugs which are poorly absorbed, tolerated and/or degraded within the GI tract. | 09-11-2014 |
| 20140276546 | Device for Selectively Reducing Absorption of Unhealthy Food - This invention is a device and method for selectively and automatically reducing absorption of unhealthy food in a person's gastrointestinal tract, while allowing normal absorption of healthy food. In an example, such a device can comprise: a food-identifying sensor; an absorption-reducing substance; an implanted reservoir; and a release-control mechanism that selectively and automatically releases the substance into the person's gastrointestinal tract when the sensor detects that the person is consuming unhealthy food. | 09-18-2014 |
| 20140276547 | PORTABLE REGULATED PRESSURE DEVICES FOR MEDICAL PROCEDURES - In various embodiments of the invention, a vacuum pump can be used as a stand alone unit to create, monitor and control a vacuum in a variety of surgical procedures. The vacuum pump can be controlled by a processor and automatically increases or decreases the vacuum based on monitoring of parameters selected from the group consisting of heart-rate of the fetus, heart rate of the mother, heart rate of patient, blood pressure of the fetus, blood pressure of the mother and blood pressure of the patient, position of the wound, position of the fetus, condition of the fetus, condition of the mother, condition of the patient. Visual or audio feedback is used to allow the care giver increased control of the pumping device while carrying out the procedure. | 09-18-2014 |
| 20140276548 | Fluid Bolus Delivery - The subject matter described herein relates to controlling and automating a delivery of one or boluses of a fluid medication to a patient. A user interface can display lists of parameters, such as a list of types of fluid in the fluid medication, a list of modes for delivery of the one or more boluses, a list of flow rates of each bolus delivery, a list of durations corresponding to each bolus, a list of initiation times of each bolus, and a list of initiation events for each bolus. In response, a clinician can select and/or specify parameters for the one or more boluses. Subsequently, the infusion device can deliver the one or more boluses based on the selected or specified parameters. Related apparatus, systems, techniques and articles are also described. | 09-18-2014 |
| 20140276549 | METHOD, APPARATUS AND SYSTEM FOR AUTOMATIC TREATMENT OF PAIN - We disclose methods and medical device systems for automated delivery of therapies for pain and determination of need for and safety of treatment. In one embodiment, such a medical device system may comprise a sensor configured to sense at least one body signal from a patient; and a medical device configured to receive a first sensed body signal from the sensor; determine a patient pain index based at least in part on said first sensed body signal; determine whether said patient pain index is above at least a first pain index threshold; determine a safety index based at least in part on a second sensed body signal; select a pain treatment regimen based on at least one of said safety index and or a determination that said pain index is above said first pain index threshold; and deliver said pain treatment regimen. | 09-18-2014 |
| 20140276550 | MEDICAL FLUID INJECTOR - Systems and methods for intelligently delivering fluid to a targeted tissue. The systems and methods may include directing a pump to distribute fluid to a targeted tissue and receiving one or more signals from an intracorporeal sensing system, where the one or more signals correspond to one or more sensed feedback parameters at the targeted tissue. The systems and methods may also include determining whether the one or more sensed feedback parameters are within an acceptable range. If the one or more sensed feedback parameters are not within the acceptable range, the systems and methods may include determining an adjusted velocity for the plunger necessary to adjust the pressure of the fluid in the pump so that the one or more sensed feedback parameters move within the acceptable range and directing the pump to distribute the fluid at the adjusted velocity. | 09-18-2014 |
| 20140276551 | EPILEPTIC SEIZURE THERAPIES COMPRISING PARTIAL REDUCTION OR COOLING OF BLOOD FLOW TO BRAIN REGIONS - We report a method of treating an epileptic seizure in a patient, comprising: detecting said epileptic seizure, based on body data from said patient; and reducing a flow of blood to a brain of said patient in response to said detected seizure; wherein said reducing is effected by at least one of: applying a pressure, applying a cooling, or administering a vasoconstrictive agent to a vessel supplying blood to at least a portion of the brain. We also report a medical device system configured to implement the method. We also report a non-transitory computer readable program storage unit encoded with instructions that, when executed by a computer, perform the method. | 09-18-2014 |
| 20140276552 | Physician-Centric Health Care Delivery Platform - A system for diagnosing and/or treating a patient comprising a patient information database for storing and retrieving patient health data related to the patient. The data includes one or more of real-time patient health information, at least one clinical practice guideline, at least one patient questionnaire and a patient medical history. At least one server is operative to access the patient information database. A computing device remotely located from the server, including a microprocessor, configured to store a computer application and is configured for communication with the server for retrieving of the patient health data. The computer application generates at least one of a patient diagnosis or a patient treatment recommendation using the retrieved patient health data. | 09-18-2014 |
| 20140309614 | Clustering of Recorded Patient Neurological Activity to Determine Length of a Neurological Event - Apparatus and method detect a detection cluster that is associated with a neurological event, such as a seizure, of a nervous system disorder and update therapy parameters that are associated with a treatment therapy. The occurrence of the detection cluster is detected when the maximal ratio exceeds an intensity threshold. If the maximal ratio drops below the intensity threshold for a time interval that is less than a time threshold and subsequently rises above the intensity threshold, the subsequent time duration is considered as being associated with the detection cluster rather than being associated with a different detection cluster. Consequently, treatment of the nervous system disorder during the corresponding time period is in accordance with one detection cluster. Treatment therapy may be provided by providing electrical stimulation, drug infusion or a combination. Therapy parameters may be updated for each m | 10-16-2014 |
| 20140330244 | Implantable Device for Manipulating Immune Cells - Systems, devices, methods, and compositions are disclosed which include an actively-controllable implantable device configured to, for example, capture and/or release biochemical and/or biological cells in a subject. | 11-06-2014 |
| 20140330245 | DELIVERY OF A THERAPEUTIC AGENT VIA INTERMITTENT INFUSION - There is provided a method of reducing or preventing catheter reflux during infusion of a therapeutic agent into a brain of a subject comprising administering the therapeutic agent to a target area of the brain by intermittent infusion at a predetermined interval. There is provided a method of treating a CNS disorder comprising administering a therapeutic agent to a target area of a brain of a subject by intermittent infusion at a predetermined interval. There is also provided a system for reducing or preventing catheter reflux during infusion of a therapeutic agent into a target area of a brain of a subject comprising an infusion device, at least one chronically implanted intracranial catheter, a monitoring device configured to monitor the target area of the brain after each infusion, and a determination unit configured to determine whether a predetermined interval is acceptable. | 11-06-2014 |
| 20140350512 | Intravascular Cerebral Catheter Device and Method of Use - Cerebral Catheter devices and methods for use are provided. The catheter devices provided may include an anti-thrombotic agent coating on the exterior surface. The catheter devices may include unique tip configurations to allow improved fluid delivery capabilities. Further, the catheter devices may also or alternatively include one or more sensor devices in communication with a controller that allow automatically adjusting the delivery of a therapeutic fluid, for example a vasodilator, in response to the condition sensed by the catheter device, such as increased pressure. Moreover, the catheter devices may also be used in conjunction with blood flow transducers to detect and timely prevent and treatment vasospasms or other conditions. Methods for preventing and treatment vasospasm, neoplasm, or other pathological conditions while prolonged using the catheter device are also provided. | 11-27-2014 |
| 20140371709 | DEVICE AND METHODS FOR TRANSVASCULAR TUMOR EMBOLIZATION WITH INTEGRATED FLOW REGULATION - A catheter assembly may be provided with a catheter body and an inflatable balloon. The catheter body has a proximal end, a distal end and a balloon inflation lumen. The inflatable balloon is attachable to the distal end of the catheter body. The balloon has an inner surface that at least partially defines an interior volume. The balloon is configured such that the interior volume can be in fluid communication with the inflation lumen of the catheter body to inflate the balloon. The balloon also has a proximal surface and a distal surface. The balloon is provided with a channel that extends through the balloon. The channel is configured to provide fluid communication between the proximal surface of the balloon and the distal surface of the balloon. Other catheter assemblies and methods of use are also disclosed. | 12-18-2014 |
| 20150011968 | Detecting Depth of Anesthesia Via Pupil Metrics - A video feed of one or more pupils of a patient can be received and processed to determine a raw measure of pupil size of the one or more pupils over time. Based on this raw measure, at least one of a) a depth of anesthesia for the patient, b) an index of cognitive activity for the patient, and c) a degree of perfusion of an anesthetic being administered to the patient to one or both hemispheres of a brain of the patient can be determined such that one or more actions can be caused to be performed. Related systems, methods, and article of manufacture are described. | 01-08-2015 |
| 20150011969 | DEVICE FOR INTERMITTENTLY OBSTRUCTING A GASTRIC OPENING AND METHOD OF USE - The present invention relates to a device for intermittently obstructing a bodily opening, such as a gastric opening, and includes a proximal member connected to a distal member by a tether. The proximal member includes an apron member surrounding a first occluding member, which is formable from an elongated and narrower configuration to a contracted or expanded but wider configuration. When employed in the stomach, the device of the present invention is arranged transluminally, with the distal member disposed in the duodenum and the proximal member disposed against the pyloric valve, intermittently occluding the pyloric valve and preventing or delaying the flow of gastric contents through the pyloric valve. In certain embodiments, a reservoir may be included for releasing a substance of interest, for example for releasing insulin from a reservoir disposed in the distal member. Sensors, actuators, and data transmission devices may also be included. | 01-08-2015 |
| 20150025494 | DRUG DELIVERY IN ASSOCIATION WITH MEDICAL OR SURGICAL PROCEDURES - Disclosed are various methods and devices for facilitating medical and/or procedures that are performed without “general anesthesia,” which is also described in the specification as the state of patient “unconsciousness” resulting from a drug administered by an anesthetist or anesthesiologist. The devices safely and effectively provide and maintain drug infusions that do not push the patient into unconsciousness and/or general anesthesia. Devices according to embodiments of the invention include the use of stored parameters and/or values that correlate to drug delivery during a procedure, and a patient health monitor to measure and send signals regarding a patient health condition to a processor or other computational device. | 01-22-2015 |
| 20150038940 | APPLIANCE FOR PERFORMING ANAESTHESIA OR ANALGOSEDATION, AND METHOD FOR OPERATING AN APPLIANCE FOR PERFORMING ANAESTHESIA OR ANALGOSEDATION - The invention relates to an appliance for performing anaesthesia or analgosedation, comprising a dosing device ( | 02-05-2015 |
| 20150045766 | MICROELECTRODE-EQUIPPED SUBDURAL THERAPEUTIC AGENT DELIVERY STRIP - An apparatus for treating the brain, comprises a first fluid delivery device including a distal end sized and shaped for placement at a first target site between a dura mater and a pia mater of the brain, the first fluid delivery device including a first fluid lumen extending to a first outlet port in the distal end to deliver fluids to a first target location and a first microelectrode mounted within the distal end of the first fluid delivery device for movement between an insertion position in which a first distal tip of the first microelectrode is received within the first fluid delivery device and a deployed position in which the first microelectrode extends out of the first fluid delivery device with the first distal tip thereof penetrating the pia mater to a first electrode target position in the cerebral cortex. | 02-12-2015 |
| 20150057635 | REDUCING DISRUPTION DURING MEDICATION ADMINISTRATION - Methods, computer systems, and computer readable media are provided for transitioning a clinical care room from a first scene to a second scene in order to facilitate completion of a medication-administration process. The first scene in the clinical care room is presented where the clinical care room has one or more zones. The first scene is associated with a first group of setting for components within the one or more zones. An input indicating that the medication-administration process has been initiated is received. Incident to receiving the input, the second scene is provided. The second scene is associated with a second group of settings for the components. The second group of settings is optimized to facilitate completion medication-administration process. | 02-26-2015 |
| 20150100037 | SYSTEM AND METHOD FOR PROVIDING ANIMAL MAINTENANCE - A system for providing animal maintenance includes a housing operable to accommodate an animal, an actuating arm coupled to the housing and to an attachment device, the attachment device is operable to perform one or more animal maintenance tasks, and the actuating arm is operable to apply the attachment device to the animal, a position sensor operable to determine the position of the animal relative to the position sensor, a restraint is operable to restrict the movement of the animal within the housing, and a processor communicatively coupled to the position sensor, the actuating arm, and the attachment device, the processor is operable to receive measurements from the position sensor and, in response to the received measurements, direct the actuating arm to apply the attachment device to the animal. | 04-09-2015 |
| 20150133888 | DRUG DELIVERY PROGRAMMING TECHNIQUES - Devices, systems, and techniques for programming drug delivery are described. Such techniques may account for diffusion and mixing of drug within the fluid or allow for more flexible programming options. In one example, a method may include determining one or more fluid delivery parameters (e.g., volume, flow rate, or period of time) for a fluid that is a mixture of two other fluids. The determination may be based on one or more fluid delivery parameters of the two other fluids and/or a concentration profile representing the mixing between the two other fluids. In other examples, drug delivery programming may be facilitated by the selection of various patterns and steps of drug delivery. The system may track volume of delivered fluid to maintain desired dosing of the patient. | 05-14-2015 |
| 20150141953 | REMOTE CLOSED-LOOP TITRATION OF DECONGESTIVE THERAPY FOR THE TREATMENT OF ADVANCED HEART FAILURE - An apparatus comprises one or more physiological sensing circuits that generate a sensed physiological signal and at least one of the physiological sensing circuits is implantable, a measurement circuit configured to recurrently measure one or more physiological parameters that indicate a status of heart failure of the subject, a comparison circuit configured to compare the one or more physiological parameter measurements to one or more physiological parameter target values, a therapy circuit configured to control delivery of one or more drugs to treat heart failure, and a control circuit in electrical communication with the comparison circuit and the therapy circuit and configured to recurrently adjust delivery of drug therapy according to the comparison of the measured physiological parameters to the physiological parameter targets. | 05-21-2015 |
| 20150148773 | FLUID SPRAYING APPARATUSES, AND RELATED SYSTEMS AND METHODS - Embodiments disclosed herein are directed to fluid spraying apparatuses, and related systems and methods. The disclosed fluid spraying apparatuses may be used, for example, to spray a medically suitable fluid on a target region of a living subject such as for treating or removing tissue. In an embodiment, a fluid spraying apparatus includes a target designation unit having a target sensor configured to sense a target region of a living subject, a spray mechanism, and a controller. The spray mechanism includes at least one reservoir configured to hold fluid, and a spraying device operably coupled to the at least one reservoir, the spraying device configured to spray the fluid in the at least one reservoir onto the target region. The controller includes control electrical circuitry operably coupled to the spray mechanism and the target designation unit, and configured to control the spray mechanism responsive to the target sensor sensing the target region. | 05-28-2015 |
| 20150324548 | MEDICATION DELIVERY SYSTEM - This disclosure comprises a system, non-transitory computer readable storage medium and method for delivering medications and/or medical treatments that are appropriate to the resilient context of an individual patient. The resilient context comprises a predictive model for each of one or more patient function measures and a predictive model of patient resilience where said models are all developed by learning from the data associated with the individual patient. The medical advice, medical diagnoses and/or medical treatments may be provided “as is” and/or they may be customized to match the specific resilient context of the individual patient. | 11-12-2015 |
| 20150343139 | IMPLANTABLE PUMPS AND RELATED METHODS OF USE - A medical device may include a pump configured to dispense an agent for treating a condition of a lung. The pump may be configured to be implanted subcutaneously into a patient. The medical device may also include a treatment device coupled to the pump and configured to deliver the agent to the lung. | 12-03-2015 |
| 20150343144 | Drug Device Configured for Wireless Communication - This invention relates to an ingestible drug delivery device configured for wireless communication with other ingestible drug delivery devices. | 12-03-2015 |
| 20150352284 | INFUSION PUMP INCLUDING PAIN CONTROLLED ANALGESIC ("PCA") APPARATUS - An infusion pump includes: a housing, a pump actuator supported by the housing, electronics configured to control the pump actuator, a pain controlled analgesic (“PCA”) input device, a cord having a remote end connected to the PCA input device and a local end connected to the housing, a remote integrated circuit; and a local integrated circuit in communication with the electronics and the remote integrated circuit so as to provide operational information concerning the PCA input device to the electronics. | 12-10-2015 |
| 20150367071 | SYSTEMS AND METHODS FOR TRACKING AND REVERSING ACCIDENTAL OVERDOSE - In one embodiment, a system for tracking and reversing accidental overdose includes a patient monitoring system configured to monitor a patient parameter that provides an indication as to whether or not the patient is overdosing, an alert system configured to activate when the patient parameter falls below an established threshold, and a reversal agent delivery system configured to automatically administer a reversing agent that counteracts the effects of an analgesic medication being administered to the patient when the patient parameter falls below the established threshold. | 12-24-2015 |
| 20160000604 | INFUSION PRESSURE CONTROL USING BLOOD PRESSURE - Methods, systems, and software for controlling infusion pressure, such as during a medical procedure, using systemic blood pressure are described. Systemic blood pressure, such as brachial arm blood pressure or radial artery blood pressure, may be used to estimate central retinal artery blood pressure to estimate critical closing pressure. Further, the disclosure relates to controlling infusion pressure to prevent an increase in intraocular pressure above the estimated critical closing pressure when such is not desired, and, when such is desired, using systemic blood pressure and infusion pressure to control an intentional increase in intraocular pressure above the estimated critical closing pressure to stop intraocular bleeding. | 01-07-2016 |
| 20160015894 | DISTRIBUTED MEDICATION DELIVERY METHOD HAVING AUTONOMOUS DELIVERY DEVICE - A method for delivering medication includes programming an operations processor of a medication delivery operations module to control the base function of medication delivery of a delivery device at a selectable rate and a selectable volume. An advanced medication delivery program is created by an advanced program processor that is part of an advanced interface module (“AIM”) located with the operations module in the same housing, although the processors are separate. When the advanced delivery program is complete and in a buffer, the operations processor executes the stored advanced delivery program under which the operations processor automatically varies at least one of the rate of delivery and volume of delivery values in accordance with the advanced delivery program autonomously without being under real time control of, or dependent on, any remote processor or data source, including the AIM. Support for PK applications is provided. | 01-21-2016 |
| 20160058957 | Method, system and device for detection of blood vessel penetration or prevention of blood vessel penetration for safely injecting liquids or gels under the skin surface - Method, system and device for blood vessel penetration prevention or blood vessel penetration detection for safe injection of liquids or gels underneath the human skin surface is disclosed, either for wrinkle treatment or for other purposes. | 03-03-2016 |
| 20160074582 | METHOD OF OPERATING A CONTROL DEVICE FOR CONTROLLING AN INFUSION DEVICE - Method of operating a control device for controlling an infusion device A method of operating a control device ( | 03-17-2016 |
| 20160078189 | Sedation system and method providing enhanced safety - A computer assisted sedation system and methods for use by a non-anesthetist procedural physician comprising an electronic controller for a drug infusion system for infusing a sedative, analgesic and/or amnestic drug to a patient having data monitors for determining the patient' physiological data and transmitting same to the controller for determining whether the patient's physiological condition is normal and if not, for signaling an alarm and providing instructions to a non-anesthesiologiest procedural physician to return the patient to a normal condition. | 03-17-2016 |
| 20160106917 | DEVICES AND METHODS FOR ADJUSTING BASAL DELIVERY PROFILE - The present disclosure presents systems, devices and methods for administration of a therapeutic fluid to the body of a patient at a transient basal delivery profile, and enabling modification of the transient profile. Some embodiments include a user interface enabling input of one or more transient basal related parameters, and a processor having a basal programming application operating thereon. The basal programming application configured for determining a transient basal profile based on at least one or more transient basal related parameters. The transient basal profile comprises a plurality of phases and wherein each of the plurality of phases is characterized by a duration and at least one basal rate. In some embodiments, at least one of the plurality of phases includes either a basal overshot or a basal undershot. Some embodiments may also include a pump for dispensing the therapeutic fluid from a reservoir to the body of the patient. | 04-21-2016 |
| 20160113843 | METHOD AND DEVICE OF DETECTING AND/OR BLOCKING REFLUX - A naso/orogastric device having backflow blocking means and comprises a naso/orogastric tube sized and shaped for being disposed within the esophagus so that at least a distal end thereof being placed in the stomach lumen of a patient, at least one elastic esophageal body, positioned along the naso/orogastric tube, having a pressure dependent volume, at least one esophageal sensor that detects fluid around at least one segment of the naso/orogastric tube, and a pressure regulator that regulates a pressure within the elastic esophageal body according to the detection. | 04-28-2016 |
| 20160143817 | CLOSED LOOP SYSTEMS AND METHODS FOR OPTIMAL ENTERAL FEEDING AND A PERSONALIZED NUTRITION PLAN - There is provided a computer-implemented method for calculating a gastric emptying rate from a stomach lumen into a small intestine of a patient, comprising: using at least one processor for executing the following during an enteral tube feeding of a stomach of the patient by a feeding mechanism: analyzing outputs of at least one stomach sensor located within the stomach for detecting a stop feeding condition; pausing the enteral tube feeding in response to a detection of the stop feeding condition; after a predefined period of time, restarting the enteral tube feeding until the stop condition is redetected by an analysis of said outputs; calculating a gastric emptying rate based on an amount of feeding content delivered during a period between the restarting and the redetection; and instructing the feeding mechanism to adapt a feeding rate of the enteral tube feeding according to the gastric emptying rate. | 05-26-2016 |
| 20160144126 | METHODS AND DEVICES FOR SAFELY POSITIONING A NEEDLE SYRINGE IN A BODY CAVITY - The present invention discloses a pressure-depending clutching device for locating and safely positioning a needle in a body cavity. The device is capable of automatically engaging and disengaging the needle from a driving force depending on the pressure experienced by needle. The device has a body with an interior space, a pressure-sensing element disposed in the body defining a portion of a pressure chamber, and a force-receiving element operatively connected to the pressure-sensing element. The force-receiving element has a shape complimentary to a portion of a force-sending element operatively connected to a force-applying structure such as a handle for a user to apply a driving force. The pressure-sensing element, the force-receiving element, and the complementary force-sending element form a driving force engaging mechanism for coupling the force-applying structure to the needle during operation. Before the needle reaches the target body cavity, the pressure in the needle causes the clutching device to assume an “engaged” state, coupling the driving force to the needle. When the needle reaches the body cavity, the change in pressure causes the clutching device to assume a “disengaged” state, disengaging the driving force from the needle, thereby, automatically positioning the needle in the cavity to avoid overshooting. Also provided are needle-and-syringe assemblies incorporating the disclosed clutching devices, methods for manufacturing the disclosed clutching devices, as well as methods for safely locating and positioning needles in the body cavity utilizing a needle-and-syringe assembly incorporating the disclosed clutching devices. | 05-26-2016 |
| 20160175522 | CLOSED LOOP ANESTHETIC DELIVERY | 06-23-2016 |
| 20160184518 | RESPIRATORY PARAMETER GUIDED AUTOMATED IV ADMINISTRATION AND IV TUBE CLAMP ACTIVATION - Disclosed is a system that includes a sensor for acquiring a physiological bioelectrical impedance signal from a patient functionally connected to the computing device. The computing device preferably analyzes the physiological bioelectrical impedance signal and provides outputs an assessment of minute ventilation of the patient based on the analyzed bioelectrical impedance signal. Preferably, the system monitors the signal over time, provides a control signal to an IV pump that instructs the IV Pump to automatically adjust medication levels by automatically lowering medication levels when respiration levels fall or completely stopping flow of the medication. | 06-30-2016 |
| 20160184520 | AUTOMATIC INJECTION OF MEDICATION INTO ANIMALS - In selected embodiments, a handheld injection safety applicator includes an applicator housing with a handle and a retractable needle housed within the applicator. The applicator further includes a first sensor that detects the presence of a user's grip on the handle and a second sensor that detects the presence of an animal. The applicator also includes processing circuitry configured to receive a first signal from the first sensor indicating that the user is gripping the handle and receive a second signal from the second sensor indicating that an animal is detected. The applicator extends the needle out of the applicator into the animal once the first and second signal are received and delivers a dose of medication into the animal once the needle is fully extended into the animal. | 06-30-2016 |
| 20160250408 | NASAL DELIVERY METHOD | 09-01-2016 |
| 20180021514 | ENHANCED CONFIRMATIONS FOR TOUCHSCREEN INFUSION PUMP | 01-25-2018 |
| 20190143040 | Control Device for Controlling the Administration of Propofol to a Patient | 05-16-2019 |
| 20220133999 | MONITORING OF PHYSIOLOGICAL PARAMETERS WITH IMPEDANCE MEASUREMENT - A system for monitoring a patient includes one or more processors and a sensor device implemented in circuitry. The system is configured to measure, using the sensor device, an impedance of tissue of the patient and determine, using one or more processors, a physiological parameter comprising at least one of a heart rate, cardiac output, vascular tone, perfusion level, fluid status, respiration effort, or respiration rate of the patient based on the impedance of the tissue of the patient. The system is configured to facilitate therapy, using the one or more processors, based on the determined physiological parameter. | 05-05-2022 |
| 20220134000 | Microdosing System, Apparatus, Method - A microdosing delivery system and method is provided to improve dosage of a drug. Exemplary embodiments include system and methods for obtaining a one or more biological metrics in order to determine the dosage of the drug. Exemplary embodiments include system and method for delivering a dosage to a user based on the one or more biological metrics. | 05-05-2022 |
