Class / Patent application number | Description | Number of patent applications / Date published |
600035000 | Artificial insemination | 73 |
20080242919 | CONCEPTION CAP AND RELATED METHODS - A conception cap includes a dome having a collapsible sidewall, an annular rim, and three or more, gripping flanges along the inner surface of the rim. The gripping flanges may effectively position and secure the cap over the cervix for the concentration of semen on the cervical os to effect fertilization independently or with the aid of biologically active agents. The cap may additionally include a handle extending from the annular rim at an angle. | 10-02-2008 |
20080269549 | METHOD, ARTICLE, AND APPARATUS FOR CRYOPRESERVATION OF BIOLOGICAL SAMPLES - Described herein is a method of storing a biological sample, such as a sperm sample, in an elongated container for cryopreservation. Multiple volumes of biological sample may be placed in each elongated container such that each volume of sample is separated from its nearest neighbor by a separation gas. The present invention further relates to an apparatus and method for loading biological samples, such as sperm samples, into an elongated container for cryopreservation of the sample material. The apparatus and method employs drawing the sample into the elongated container such that individual sample volumes are interspaced by gaps of separation gas. This alternating pattern may be created by repeatedly contacting and removing the elongated container from the sample under suction pressure. The apparatus further incorporates the use of a computer to control the volume and number of aliquots as desired. A container according to such methods is also provided. | 10-30-2008 |
20090023980 | Animal Insemination Sheath Apparatus - The present invention includes apparatuses for artificially inseminating animals which prevents contaminants from entering the opening at the end of an insemination sheath during insertion through the reproductive tract of an animal. A thin protective cover or membrane is provided at the tip of the sheath to seal it, the membrane being designed to rupture under the pressure from the seminal fluid being applied by the plunger used to eject the semen from the insemination gun. The protective cover can be an integrated portion of the sheath itself, or a material applied to the tip of the sheath. The protective cover is minimal in size as to not increase the diameter of the artificial insemination device so that there is no loss in tactile sensitivity to the breeder who must maneuver the invention through the animal's reproductive tract. | 01-22-2009 |
20090030268 | ARTIFICIAL BREEDING TECHNIQUES FOR BOVINES INCLUDING SEMEN DILUENTS AND AI APPARATUS - In the preferred embodiment, bovine semen is mixed with a suitable solution to form an insemination medium which is injected into the reproductive organs of a female bovine to flood the uterine horns in a nonsurgical AI procedure. The invention includes an AI instrument having a disposable, single use pipette that may be used with this nonsurgical procedure. The AI instrument does not include a balloon and is referred to as “catheter free”. Preferably, the uterine horns are flooded concurrently, but in the alternative, they may be flooded sequentially. | 01-29-2009 |
20090156890 | PEROXISOME PROLIFERATOR-ACTIVATOR RECEPTOR DELTA (PPARDELTA) AND THE DEVELOPMENT OF PREIMPLANTATION EMBRYOS - Methods and compositions for enhancing development of a preimplantation mammalian embryo and for increasing the live birth potential of an in vitro fertilized mammalian embryo are disclosed. An in vitro method of activating the peroxisome proliferator activated receptor δ (PPARδ) in a preimplantation mammalian embryo comprises culturing an embryo in an embryo culture medium, and upon or after commencement of expression of PPARδ in the cells of the embryo, activating the PPARδ by adding an amount of a PPARδ ligand to said medium effective to bind to PPARδ to deter apoptosis in the cells of the cultured embryo and/or increase proliferation of the cells of the cultured embryo. | 06-18-2009 |
20090216074 | Methods and Compositions for Improved Cattle Longevity and Milk Production - A single nucleotide polymorphic site at position 10793 of the bovine POU1F1 gene is associated with improved longevity and milk product traits. Disclosed are nucleic acid molecules, kits, methods of genotyping and marker assisted bovine breeding methods. | 08-27-2009 |
20090281370 | IN VITRO FERTILISATION - The present invention relates to a method and a system for producing a mammalian pre-embryo and a stem cell having a better quality than prior art methods. The system comprises means for obtaining a mammalian oocyte, and means for obtaining a mammalian spermatozoa, and an apparatus having at least two separate air-tight chambers, for which the oxygen tension of one chamber may be changed independent of the oxygen tension of the other chamber, said at least two separate air-tight chambers constitute a main chamber and at least one residence chamber. The method for in vitro producing a mammalian pre-embryo comprising the steps: a1) providing a mammalian oocyte, a2) providing a mammalian spermatozoa, b) culturing the oocyte and the spermatozoa, c) fertilizing the oocyte with the spermatozoa obtaining a fertilized oocyte, and d) allowing cell-division of the fertilized oocyte obtaining a multicellular pre-embryo wherein at least one of the steps a1) or a2) is conducted at an oxygen tension below 15%, or e) allowing cell-division of the fertilized oocyte obtaining a multicellular pre-embryo, wherein the culture is performed at an oxygen tension allowing cultivation of the cells and wherein at least one of the steps comprises a change in the oxygen tension Stem cells are produced from the multicellular pre-embryo. | 11-12-2009 |
20090281371 | ARTIFICIAL BREEDING TECHNIQUES FOR BOVINES INCLUDING SEMEN DILUENTS AND AI APPARATUS - In the preferred embodiment, bovine semen is mixed with a “suitable solution” to form an insemination medium which is injected into the reproductive organs of a female bovine to flood the uterine horns in a nonsurgical AI procedure. The invention includes an AI instrument having a disposable, single use pipette that may be used with this nonsurgical procedure. The AI instrument does not include a balloon and is referred to as “catheter free”. Preferably, the uterine horns are flooded concurrently, but in the alternative, they may be flooded sequentially. | 11-12-2009 |
20090318751 | Apparatus for Communicating with a Memory Tag and Use of the Same - A work station comprises a surface ( | 12-24-2009 |
20090326316 | METHODS OF ASSESSING THE RISK OF REPRODUCTIVE FAILURE BY MEASURING TELOMERE LENGTH - The invention features a method of identifying oocytes with a risk of reproductive failure and/or aneuploidy based on a telomere length assay. | 12-31-2009 |
20090326317 | Instrument for intra-uterine transfer via the natural vagino-uterine route - Instrument for intra-uterine transfer by the natural vagino-uterine route, including a catheter ( | 12-31-2009 |
20100113867 | METHODS FOR MAINTAINING GENETIC STABILITY OF INBRED ANIMAL STRAINS - The present invention provides novel methods of maintaining genetic stability of non-human animal inbred strains. In the methods, pedigree-tracked cryopreserved embryos or gametes or pre-gametes derived from a foundation colony are produced and used to re-establish the foundation colony at appropriate intervals. | 05-06-2010 |
20100137676 | N-ACETYLCYSTEINE AMIDE (NAC AMIDE) FOR TREATMENT OF OXIDATIVE STRESS ASSOCIATED WITH INFERTILITY - An in vitro culture and/or fertilization medium containing N-acetylcysteine amide (NAC amide) reduces or prevents oxidative stress and free radical formation that contribute to the cellular damage and eventual demise of sperm, oocytes and embryos that are cultured, fertilized and maintained in vitro. The NAC amide-containing medium composition for in vitro culture and fertilization is suitable for use in the culture of oocytes, in the culture and development of early embryos, in the preparation or culture of sperm, and in the pre-treatment of oocytes or sperm. The NAC amide-containing composition supports the growth of viable embryos until blastocyst stage. | 06-03-2010 |
20100174133 | Apparatus and method for processing microscopic single cell biological specimens with a single microtool - An oocyte and embryo-positioning apparatus enables a plurality of oocytes, embryos or other cell specimens to be held and positioned for injection therein of fluid molecular reagents such as DNA, RNA, protein, cells, spermatozoa and cells; and removal of cells, fragments of cells, cytoplasm, nuclei and cellular organelles. The oocytes and embryos are kept separate from each other in open marked or unmarked well-compartments that are located in the culture container. Each well-compartment comprises one or more finger like structures that can position one oocyte or one embryo. The lanes between the digits of the fingers may be sloped allowing the oocytes or embryo to position at the narrowest and lowest point of the compartment. The method and oocytes and embryo-positioning apparatus of this invention includes a culturing container, such as a Petrie dish, in which the oocytes and embryos are held for micromanipulation. The Petrie dish preferably contains a plurality of the oocyte or embryo-holding finger like-structures which can be positioned in the Petrie dish in a predetermined pattern. For example, the well-compartments can be positioned in the Petrie dish as a strip of well-compartments between the 12 o'clock and 6 o'clock positions, or in any other planned deployment. Marked well-compartments can be identified by letters or numbers or symbols. | 07-08-2010 |
20100179378 | Insemination catheter for artificial insemination in animals - The invention discloses an improved insemination catheter for artificial insemination in animals, characterized in which a center orifice disposed at the rear end of the nozzle for connecting the catheter tube is a blind orifice, and a diversion slit is configured between and connecting the front end of center orifice and the front end of nozzle, the diversion slit being opened when semen in the catheter tube is being squeezed and closed when semen in the catheter tube is not being squeezed. As such, the front end of the nozzle would be closed when it is inserted along with the catheter tube into the vaginal orifice of female animal body during artificial insemination such that contaminants from outside the female animal body or lubricant used will not flow into the center orifice of the nozzle, thereby enhancing the safety of artificial insemination. When the animal semen is squeezed in from the rear end of catheter tube, the diversion slit will open under pressure to allow the semen to be released smoothly, rapidly and accurately into the animal uterus, thereby enhancing the efficiency of artificial insemination. Under the circumstance where the diversion slit is closed when not under pressure, semen flown into the animal uterus or amassed around the cervix will not back flow into the center orifice of nozzle or the catheter tube, thereby reducing wasteful outflow of semen and increasing the chance of conception. | 07-15-2010 |
20100191041 | Reproductive technology of low dose semen production and in vitro / in vitro fertilization in domestic animals - Artificial insemination of female animals and in vitro fertilization of oocytes with fresh or frozen-thawed semen have been applied to the reproduction of animals. According to the traditional theory and conventional procedures, a great number of sperm cells are needed to ensure a successful fertilization. | 07-29-2010 |
20100191042 | Production methology for frozen dairy - A reduced dose inseminate and method for producing and using such reduced dose inseminate to fertilize the eggs of a female animal by artificial insemination with fewer sperm cells than compared with conventional dose inseminates. | 07-29-2010 |
20100234673 | Suitable Apparatus for Precisely and Reproducibly Transferring a Fertilized Egg-Cell (Embryo) to the Uterus - The subject of the present invention is in vitro fertilisation (IVF) and intracytoplasmic sperm injection (ICSI), and relates to an apparatus with which embryo transfer can be standardised and which, in comparison with the currently used technique, may possibly result in higher pregnancy rates. This is realised by using an apparatus with which it is possible to precisely and reproducibly aspirate one or two embryos from a Petri dish and to transfer them to the uterus, to a particular distance from the fundus. It has been shown that the chance of pregnancy is best if the distance between the embryo and the fundus is 1-2 cm. | 09-16-2010 |
20100234674 | MICROFLUIDIC SYSTEMS AND METHODS - Microfluidic systems and methods. A microfluidic device for in vitro fertilization comprises a substrate and a plurality of microchannels disposed in the substrate, including an inlet of at least two of the plurality of microchannels arranged on the substrate to align with a fluid-handling device. Another microfluidic system for assaying a plurality of cells comprises a substrate and a plurality of microfluidic channels comprising a source channel, a sink channel, and a cell chamber. An insert for a microfluidic system comprises a substrate configured to be inserted into a dish and a plurality of microscale wells disposed in the substrate. A microfluidic channel comprises a substrate and at least one microchannel having an open inlet, an open outlet, a channel, and an opening in the substrate disposed over a portion of the channel. A device for providing an amount of fluid for a fluidic system comprises a main reservoir, an aspiration well, tubing coupling the reservoirs, and a seal closing the main reservoir. Air tubing having a hydrophobic end extends into the at least one aspiration well. | 09-16-2010 |
20100234677 | REPRODUCTIVE MANAGEMENT - A method for breeding bovines, especially a method for breeding dairy and beef cattle without use of heat detection prior to insemination or embryo implantation. | 09-16-2010 |
20100274073 | Methods and Devices for Predicting Ovulation and Optimum Insemination Time of Animals - Manual techniques for monitoring animal ovulation cycle have been used commercially to determine the best time to breed animals. Techniques using heat as an indicator for ovulation do not always correspond to ovulation. The present invention provides methods, apparatus, and kits for monitoring and predicting ovulation using an automated hand-held device, incorporating a computer and probe for detecting physical changes in the animal body fluid. Changes in electrolyte levels are detected as alterations in resistance which corresponds to specific intervals in the ovulation cycle. The present invention provides a rapid, low cost means for monitoring mammalian ovulation cycles and a tool for use in artificial insemination, especially in assessing large populations of animals. | 10-28-2010 |
20100305396 | METHOD AND APPARATUS FOR CREATING A PATHWAY IN AN ANIMAL - A method and apparatus for safer and more effective deep trans-cervical intra-uterine artificial insemination (AI) is provided. Such a deep AI catheter causes minimal discomfort and risk of trauma, and does not require the services of a highly trained AI professional. First, a catheter is inserted into the cervical tract of the animal. A membrane, initially positioned inside a tube section of the catheter, is then extended from an opening in the tube and into the tract under pressure. The membrane extends into the tract without friction thereby reducing the discomfort and the risk of trauma or injury to the animal. When the membrane is fully extended into the tract, pressure causes the tip of the membrane to open thereby releasing the AI fluid and depositing the genetic material suspended in the fluid into the reproductive tract. In addition to AI and embryo transplant, other applications for the pathway include other therapeutic, diagnostic or procedures, such as introducing fluoroscopic cameras, instruments, and drug delivery. | 12-02-2010 |
20100312045 | POLYPEPTIDES COMPRISING AN ICE-BINDING ACTIVITY - The present invention relates to novel polypeptides comprising an ice-binding capability resulting in an ice crystal formation and/or growth reducing or inhibiting activity. The present invention also relates to an edible product and to a solid support comprising the novel polypeptide. Furthermore, the present invention also relates to a method for producing the novel polypeptide and to different uses of the novel polypeptide. | 12-09-2010 |
20100317916 | Method for relative quantitation of chromosomal DNA copy number in single or few cells - The present invention is directed to methods for determining the presence or absence of a genetic defect in an IVF embryo prior to transfer comprising performing real-time PCR and 2 | 12-16-2010 |
20100317917 | FERTILITY ENHANCEMENT USING LIPID CARRIERS AND BIOACTIVE MOLECULES - The invention relates to a method for enhancing fertilization. Fertilization enhancement is achieved by effectively delivering bioactive molecules with a lipid anchor, (GPI-linked proteins), in the presence of a lipid carrier to the surface of epididymal or ejaculated sperm. The enhanced sperm are used for fertilization via in vitro fertilization or intrauterine insemination | 12-16-2010 |
20100331610 | Artificial insemination device for animals - An improved artificial insemination device for animals is disclosed. The device has an inner catheter tube inserted inside a catheter tube where the front end of the inner catheter tube is closed in arc shape and its periphery is arranged with a plurality of spray release openings with arc-shaped invagination at outer edges and an extension member that communicates with the interior. As such, when the front end of the inner catheter tube enters the uterus along the cervical tract, it will not scratch the walls of cervical tract during movement because the outer edges of the spray release openings are in arc invaginated shape. When the contraction of the uterus sucks out the animal semen inside the inner catheter tube, it works like a straw through the extension members of the spray release openings, and the semen pooled together inside the catheter could be released rapidly and smoothly into different parts of the uterus to fully enhance the efficiency and the success rate of artificial insemination. | 12-30-2010 |
20100331611 | EMBRYO IMPLANTATION - The present invention relates to a method for detecting an optimal time for embryo implantation in mammals, particularly humans. In particular, the invention relates to a method for determining the optimal time for implantation of an embryo in a mammalian endometrium comprising detecting the levels of an endocannabinoid in the early, mid and late stage of the menstrual cycle in a subject. | 12-30-2010 |
20110021867 | ANIMAL INSEMINATION SHEATH AND METHODS OF USE - The present invention includes methods and apparatus for depositing materials in the reproductive tract of an animal, such as antibiotics or semen for artificial insemination, using an improved device that covers the end of a sheath inserted into the reproductive tract. A thin protective membrane is provided at the tip of the sheath having a tiny pre-ruptured prick opening therein that is designed to rupture under increased pressure from the fluid inside the sheath. The protective cover can be an integrated portion of the sheath itself, or a material applied to the tip of the sheath. The protective cover is minimal in size as to not increase the diameter of the sheath so that there is no loss in tactile sensitivity to a physician or breeder who must maneuver the invention through the reproductive tract of the animal. | 01-27-2011 |
20110034758 | Cartridge For A Biological Sample - A sealed removable cartridge adapted for insertion into an assay device and adapted to contain a biologic sample, the cartridge comprising: two or more assay locations adapted to facilitate, within said cartridge, two or more assays of said biologic sample; and an actuator interface adapted to interface with an actuator of said assay device, to transport said biologic sample towards at least one of said assay locations. | 02-10-2011 |
20110065981 | Methods and Compositions for Improved Fertilization and Embryonic Survival - Single nucleotide polymorphic sites at positions 19069 and 25402 of the bovine STAT3 gene are associated with improved fertilization rate and/or improved embryo survival rate. The interactions between these two polymorphisms, and between them and the bovine STAT1 gene and fertilization and early embryonic survival rates were also disclosed. The interactions between STAT3 SNPs, and between STAT1 and STAT3 SNP19069 were highly significant for embryonic survival rate. Also disclosed are nucleic acid molecules, kits, methods of genotyping and marker assisted bovine breeding methods. | 03-17-2011 |
20110087065 | Artificial Insemination Device - An artificial insemination device includes a catheter, a widening tip connected to one end of the catheter for being introduced into the genital system of a female animal, and a check valve connected between the catheter and the widening tip and having a stopper supported on a spring between a first stop wall and a second stop wall for controlling the passage in the second stop wall for allowing the injected semen to pass out of the semen outlet in the first stop wall and prohibiting the injected semen from flowing backwards | 04-14-2011 |
20110207993 | METHOD FOR ARTIFICIAL INSEMINATION OF COWS - The present invention is related to a method of artificial animal reproduction by which healthy cows and heifers are impregnated on the first attempt at artificial insemination. The sperm is deposited at the time the uterine horns are at the optimum time to conceive. | 08-25-2011 |
20110218391 | METHOD FOR MONITORING ESTRUS AND OVULATION OF ANIMALS, AND FOR PLANNING A USEFUL FERTILIZATION TIME ZONE AND A PREFERRED FERTILIZATION TIME ZONE - Estrus of animals and particularly sows is determined for planning of a preferred time period of insemination by a sensing system arranged to detect standing of the animal. Data from the sensing system is collected and analyzed using an algorithm and information that is displayed on an indicating system to provide an indication to a worker of the time period of estrus and ovulation and of a useful insemination time period and a preferred insemination time period of the animal. The indicating system includes a countdown clock to the preferred time period of insemination. In the event that the insemination fails, an indication is provided about whether the actual time of insemination occurred at the preferred time of insemination indicated to the worker. When estrus is completed, a confidence level is provided about the likelihood of success based on the position of the actual time of insemination relative to ovulation. | 09-08-2011 |
20110251451 | METHOD AND APPARATUS FOR CREATING A PATHWAY IN AN ANIMAL - A method and apparatus for safer and more effective deep trans-cervical intra-uterine artificial insemination (AI) is provided. Such a deep AI catheter causes minimal discomfort and risk of trauma, and does not require the services of a highly trained AI professional. First, a catheter is inserted into the cervical tract of the animal. A membrane, initially positioned inside a tube section of the catheter, is then extended from an opening in the tube and into the tract under pressure. The membrane extends into the tract without friction thereby reducing the discomfort and the risk of trauma or injury to the animal. When the membrane is fully extended into the tract, pressure causes the tip of the membrane to open thereby releasing the AI fluid and depositing the genetic material suspended in the fluid into the reproductive tract. In addition to AI and embryo transplant, other applications for the pathway include other therapeutic, diagnostic or procedures, such as introducing fluoroscopic cameras, instruments, and drug delivery. | 10-13-2011 |
20110275886 | METHOD TO SELECT ANIMALS WITH A HIGH CAPACITY OF EMBRYO PRODUCTION - The present invention provides a method to select a non-human female animal subject having the capacity to produce appropriate number of transferable embryos or fertilizable oocytes in said animal, said method comprising the determination of the anti-Mullerian hormone concentration in a biological sample before an ovarian superovulatory treatment. The present invention is further directed to the use of AMH as a predictive marker of number of transferable embryos or fertilizable oocytes able to be produced in a non-human female animal. | 11-10-2011 |
20110282135 | Device and method for artificial insemination of bovines - An artificial insemination system and its use requires a sheath, a pumping device, and an AI gun-straw of semen assembly. As intended for the present invention, the AI gun-straw of semen assembly is insertable into the central lumen of the sheath. There, the distal end of the straw of semen is insertable into a slidable insert, which, in turn, is insertable into a transfer tunnel. Last, the transfer tunnel opens into an ejection port in the ventrodistal portion of the sheath. | 11-17-2011 |
20120046518 | Estrus Synchronization Preparations & Effective CIDR-Less Protocols - An injectable preparation of estrogenic and progestrogenic hormonal compounds in an anhydrous excipient injected to synchronize estrus in non-menstruating placental female animals, and a five to nine day protocol to apply the unique preparation to achieve estrus synchronization. | 02-23-2012 |
20120046519 | METHOD AND COMPOSITION FOR SYNCHRONIZING TIME OF INSEMINATION - Methods and compositions for synchronizing the time of insemination in swine are described. More particularly, methods are described for synchronizing the time of insemination by administration of a composition comprising a hormone, wherein the swine is inseminated only one time after administration of the hormone, and wherein there is no heat detection. | 02-23-2012 |
20120059215 | METHOD OF COLLECTING SEMEN FROM LAB ANIMALS AND ARTIFICIAL INSEMINATION METHOD THEREOF - The present invention relates to a method of collecting semen from the epididymis or the testis of a lab animal and an artificial insemination method thereof. The present invention relates to a new applicable method in the animal production field using artificial insemination. Since the present invention solves the problems of the conventional method of artificial insemination of lab animals, it is excellent in terms of the pregnancy rate and productivity; is time-efficient; and is superior in economic and industrial respects by preventing a huge economic loss due to the costs for maintaining the mass breeding of animals. | 03-08-2012 |
20120078036 | PROBE FOR ARTIFICIAL INSEMINATION, IN PARTICULAR FOR PIGS - The present invention relates to a probe for artificially inseminating an animal, including: a cylindrical body to be inserted inside the vagina of the animal and ending in a distal element provided with a discharge opening; and a storage space for semen to be injected. The cylindrical body consists of a hollow tube, and the storage space comprises a flexible tube that is molded onto the proximal end of the cylindrical body on one side and onto a plug on the other side, said plug allowing the storage space to be filled under pressure. In the inoperative position, after being filled, the semen is located mainly in the expanded flexible tube while an overpressure prevails inside the cylindrical body. In the operative position, when the flexible tube is outside the vagina of the animal, the semen is moved into the entire cylindrical body through the discharge opening under the effect of suction and of the contraction of the flexible tube returning to the original volume thereof. | 03-29-2012 |
20120197067 | Nutritional Composition for Equine Reproductive Health - An equine nutritional composition comprising: i) a first component comprising micronutrients, wherein said micronutrients include: the amino acids L-carnitine, L-arginine, L-cysteine and, optionally, L-lysine; folate; and, at least one mineral element selected from the group consisting of: selenium, iron, calcium, magnesium, copper, zinc and manganese; and, ii) a second component comprising one or more fatty acids selected from each of the groups: omega-3 fatty acids; and, omega-6 fatty acids. The equine nutritional composition has utility in improving aspects of the reproductive health of stallions. | 08-02-2012 |
20130041209 | METHODS AND COMPOSITIONS FOR IMPROVED FERTILIZATION AND EMBRYONIC SURVIVAL - Single nucleotide polymorphic sites of the bovine HSP genes are associated with improved fertilization rate and/or improved embryo survival rate in cattle. Nucleic acid molecules, kits, methods of genotyping and marker assisted bovine breeding methods based on these SNPs are disclosed. | 02-14-2013 |
20130041210 | Process for the Synchronization of Ovulation for Timed Breeding Without Heat Detection - A method for synchronizing ovulation in sows and gilts by a single injection of hormones is disclosed. A hormone, gonadotropin releasing hormone (GnRH), luteinizing hormone (LH), follicle stimulating hormone (FSH), human chorionic gonadotropin (hCG), analogues, derivatives, agonists or combinations thereof is administered to an open sow post weaning at a specific time to stimulate ovulation of mature responsive follicles. The sow is then bred, without heat detection, at a specific subsequent timed interval after injection with hormone, with one or two artificial or natural breedings. In gilts, the hormone is injected at a timed interval from onset of estrus or at a specific timed interval following Prostaglandin F2a for those gilts which have been held in a state of pseudopregnancy. | 02-14-2013 |
20130060079 | COMPOSITIONS AND METHODS FOR AUTOLOGOUS GERMLINE MITOCHONDRIAL ENERGY TRANSFER - Oogonial stem cell (OSC)-derived compositions, such as nuclear free cytoplasm or isolated mitochondria, and uses of OSC-derived compositions in autologous fertility-enhancing procedures are described. | 03-07-2013 |
20130085321 | Process for the Synchronization of Ovulation for Timed Breeding Without Heat Detection - A method, for synchronizing ovulation in sows and gilts by a single injection of hormones is disclosed. A hormone, gonadotropin releasing hormone (GnRH), luteinizing hormone (LH), follicle stimulating hormone (FSH), human chorionic gonadotropin (hCG), analogues, derivatives, agonists or combinations thereof is administered to an open sow post weaning at a specific time to stimulate ovulation of mature responsive follicles. The sow is then bred, without heat detection, at a specific subsequent timed interval after injection with hormone, with one or two artificial or natural breedings. In gilts, the hormone is injected at a timed interval from onset of estrus or at a specific timed interval following Prostaglandin F2a for those gilts which have been held in a state of pseudopregnancy. | 04-04-2013 |
20130085322 | PROCESS FOR THE SYNCHRONIZATION OF OVULATION FOR TIMED BREEDING WITHOUT HEAT DETECTION - A method for synchronizing ovulation in sows and gilts by a single injection of hormones is disclosed. A hormone, gonadotropin releasing hormone (GnRH), luteinizing hormone (LH), follicle stimulating hormone (Fail human chorionic gonadotropin (hCG), analogues, derivatives, agonists or combinations thereof is administered to an open sow post weaning at a specific time to stimulate ovulation of mature responsive follicles. The sow is then bred, without heat detection, at a specific subsequent timed interval after injection with hormone, with one or two artificial or natural breedings. In gilts, the hormone is injected at a timed interval from onset of estrus or at a specific timed interval following Prostaglandin F2a for those gilts which have been held in a state of pseudopregnancy. | 04-04-2013 |
20130172667 | Microfluidic Embryo and Gamete Culture Systems - A robotic microfluidic incubator system has a thin transparent sidewall and close proximity of the embryo/oocyte/cultured cells to the sidewall allow close approach of a side view microscope with adequate focal length for mid to high power. This arrangement permits microscopic examination of multiple culture wells when arranged in rows (linear or along the circumference of a carousel). Manual or automated side to side movement of the linear well row, or rotation of the carousel, allows rapid inspection of the contents each well. Automated systems with video capability also allow remote inspection of wells by video connection or Internet connection, and automated video systems can record oft-hours inspections or time lapse development in culture (i.e. embryo cell division progression, or axon growth in neuron cell cultures). | 07-04-2013 |
20130204076 | INTEGRATED MICROFLUIDIC DEVICE FOR SINGLE OOCYTE TRAPPING - An integrated microfluidic device and its usage are provided. The microfluidic device comprises an upper layer ( | 08-08-2013 |
20130267770 | GENETIC TESTING FOR IMPROVED CATTLE FERTILITY - Arrays of nucleic acid molecules, kits, methods of genotyping and marker assisted bovine breeding methods based on novel SNPs on genes of the bovine transforming growth factor-β (TGF-β) signaling pathway for improved bovine fertilization rate. The methods and compositions of the present invention are related to SNPs in the DNA-binding protein inhibitor 3 (ID3) gene, and in the bone morphogenetic protein 4 (BMP4) gene corresponding to position 2702 of SEQ ID NO: 2. Also disclosed are methods for determining viability of developing bovine embryos by measuring the expression level of one or more target genes in the TGF- signaling pathway, and selecting for implantation only embryos whose target gene expression level is not up-regulated. | 10-10-2013 |
20130267771 | ARTIFICIAL INSEMINATION STRAW - [Problem] To improve the conception chance of semen after cryopreservation by improving conventional straws for artificial insemination. [Solution] A straw for cryopreservation is produced by introducing a partitioning layer into a straw for artificial insemination to separate layers, thereby forming a semen storage layer comprising an aqueous solution containing semen and an anti-freeze agent on one side and a dilution layer containing no anti-freeze agent on the other side, wherein a dilution solution comprising an aqueous solution containing tris(hydroxymethyl aminomethane), citric acid, glucose and sodium chloride is used in the dilution layer. | 10-10-2013 |
20130345497 | Multi-Compartment Container for Biological Liquids - A multiple chambered container for biological liquids useful in artificial insemination is disclosed. | 12-26-2013 |
20140039246 | MAMMALIAN REPRODUCTION - The invention is designed to enhance mammalian reproduction and in particular to improve the use of existing artificial insemination catheters in combination with novel products and processes for the insemination of mammals such as pigs. The invention comprises a controlled/sustained release delivery system comprising a metabolite/carrier combination based on specific gels, polymers and/or other molecular complexes for metabolite delivery at the point of insemination en order to promote aspects of spermatozoa function. | 02-06-2014 |
20140046126 | TWO-DIMENSIONAL BAR CODES IN ASSISTED REPRODUCTIVE TECHNOLOGIES - A container suitable for storing biological material which is laser etched with a two-dimensional bar code and methods for producing the same. The container can be in the form of a straw having a thickness between about 0.1 mm and about 0.3 mm or can be in the form of another container that holds multiple straws. The laser etched mark can be in the form of a two-dimensional bar code may be located on an exterior surface of the container, and when the container is a straw, it remains unwarped and impermeable to fluids. | 02-13-2014 |
20140088345 | SINGLE CHANNEL, MULTIPLE DRUG DELIVERY DEVICE AND METHODS - Devices and methods are provided for drug delivery. The device may include a housing configured for intralumenal deployment into a human or animal subject and a reservoir contained within the housing and having an actuation end and a release end. The release end may include at least one outlet. A first drug formulation and a second drug formulation may be disposed within the reservoir and adjacent to each other and immiscible, or separated from each other by a first barrier. The device may also include a plug within the reservoir at the actuation end, the plug being movable toward the release end to drive the first and second drug formulations out of the reservoir. The device may also include an actuation system operably connected to the actuation end of the reservoir and configured to drive the plug toward the release end and release the drug formulations from the reservoir. | 03-27-2014 |
20140088346 | MULTIPLE RESERVOIR DRUG DELIVERY DEVICE AND METHODS - Devices and methods are provided for drug delivery. The device may include a housing configured for intralumenal deployment into a human or animal subject and first and second reservoirs within the housing, each reservoir having an actuation end, an opposed release end, and a plug moveable from the actuation end toward the release end. First and second drug formulations may be contained in the first and second reservoirs, respectively. The device may also include one or more actuation systems configured to drive the first and second plugs so as to drive the first and second drug formulations from the first and second reservoirs. The housing may include a porous membrane sidewall in fluid communication with the release ends of the first and second reservoirs, the porous membrane sidewall being configured to distribute the first and second drug formulations driven from the first and second reservoirs. | 03-27-2014 |
20140194677 | ESTRUS SYNCHRONIZATION PREPARATIONS AND EFFECTIVE CIDR-LESS PROTOCOLS - An injectable preparation of estrogenic and progestrogenic hormonal compounds in an anhydrous excipient injected to synchronize estrus in non-menstruating placental female animals, and a five to nine day protocol to apply the unique preparation to achieve estrus synchronization. | 07-10-2014 |
20140296621 | REPRODUCTIVE INFUSION DEVICE - A reproductive infusion device for collection of semen for in-home insemination. The device features a collection vessel having a collection cavity defined by a sidewall which communicates through an elongated member extending therefrom. The collection vessel removably engages coaxially with an injection component to transfer collected semen thereto. A plunger engageable with an axial cavity of the injection component is provided for vaginal deposit of collected semen. | 10-02-2014 |
20140309488 | INSEMINATION APPARATUS AND METHOD - An apparatus and method for in vivo fertilization through self-insemination includes sleeve fabricated of soft silicone elastomer having a tubular portion and a distal bulbous head. The sleeve may be secured concentrically about a syringe approximating the size, configuration, and feel of a human penis. The bulbous head includes lobes arrayed at equal angles about the head, adjacent lobes being separated by narrow channels extending longitudinally to provide a flow space for air and fluids. The distal stem of the syringe extends through the sleeve at the distal end thereof. Thus seminal fluid discharged from the syringe will be ejected out of the central opening in the head of the sleeve. | 10-16-2014 |
20140330071 | METHODS AND COMPOSITIONS FOR IMPROVED FERTILIZATION AND EMBRYONIC SURVIVAL - Single nucleotide polymorphic sites of the bovine HSP genes are associated with improved fertilization rate and/or improved embryo survival rate in cattle. Nucleic acid molecules, kits, methods of genotyping and marker assisted bovine breeding methods based on these SNPs are disclosed. | 11-06-2014 |
20140350329 | INORGANIC PYROPHOSPHATE AND USES THEREOF - The present invention provides a new and improved sperm stimulating additive comprising a certain amount of inorganic pyrophosphate (PPi). Addition of PPi in the media for human/animal in vitro fertilization (IVF) improves fertilization rate; addition of PPi in the semen extender for farm animal artificial insemination (AI) may improve pregnancy rates; furthermore, mamalian oocytes matured in vitro in a medium including PPi attain improved fertilization and developmental potential, while embryos cultured in medium supplemented with PPi have improved development to blastocyst. | 11-27-2014 |
20150018605 | EMBRYO CULTURE METHODS AND MEDIA - Improved methods of culturing embryos in media having amounts of lactate that have not previously been recognized as beneficial for embryo development. Also, compositions, devices and kits related to the same. | 01-15-2015 |
20150051441 | EMBRYO IMPLANTATION - The present invention relates to methods of and compositions comprising cytokines for, improving the success rate of embryo implantation and the success rate of pregnancy rates in females, by providing an immunopermissive uterine environment prior to insemination or implantation of embryos. The methods of the present invention are used to make the uterus more receptive or less hostile to, for example, transferred embryos, sperm or other allografted tissue. | 02-19-2015 |
20150105610 | MULTIPLE RESERVOIR DRUG DELIVERY DEVICE AND METHODS - Devices and methods are provided for drug delivery. The device may include a housing configured for intraluminal deployment into a human or animal subject and first and second reservoirs within the housing, each reservoir having an actuation end, an opposed release end, and a plug moveable from the actuation end toward the release end. First and second drug formulations may be contained in the first and second reservoirs, respectively. The device may also include one or more actuation systems configured to drive the first and second plugs so as to drive the first and second drug formulations from the first and second reservoirs. The housing may include a porous membrane sidewall in fluid communication with the release ends of the first and second reservoirs, the porous membrane sidewall being configured to distribute the first and second drug formulations driven from the first and second reservoirs. | 04-16-2015 |
20150133727 | APPARATUS AND METHODS FOR ACCESSING AND SEALING BODILY VESSELS AND CAVITIES - Everting balloon systems and methods for using the same are disclosed herein. The systems can be configured to access and dilate body lumen and cavities. For example, the systems can be used to dilate the cervix and access the uterine cavity. The systems can also be used to occlude the cervix. The systems can also be used to occlude the urethra. | 05-14-2015 |
20150141744 | CONTAINER BAG FOR CONTAINING SEMEN FOR ARTIFICIAL INSEMINATION OF ANIMALS - The present invention relates to a container bag ( | 05-21-2015 |
20150297332 | Sanitary sheath for a syringe for insemination by straw and its method of manufacture - The sheath ( | 10-22-2015 |
20150313638 | METHOD AND APPARATUS FOR ARTIFICIAL INSEMINATION - The object of the invention is to provide a device and means for artificial insemination. The present invention provides two methods of sperm delivery that aim to increase the success of intracervical artificial insemination. The shape and design of the present invention also allows artificial insemination to be a pleasurable experience. | 11-05-2015 |
20150320443 | Apparatus including a Cylindrical Body and a Nub - An apparatus includes a substantially cylindrical body including an end portion having rounded edges and at least one opening. The apparatus further includes a nub extending from the end portion proximate to the at least one opening. The nub includes a substantially rounded end. | 11-12-2015 |
20150320444 | Apparatus Including a Cylindrical Body and a Nub - An apparatus may include a plunger and a substantially cylindrical body. The substantially cylindrical body may include an end portion having rounded edges and may define a cavity sized to receive the plunger. The substantially cylindrical body may include at least one opening extending from the cavity to an external surface. The at least one opening may a substantially irregular shape. In some embodiments, the at least one opening may extend from the cavity through a nub to the external surface. The nub may have a rounded shape. In some embodiments, the substantially irregular shape may include one of a slit, an oval shape, an elliptical shape, an hourglass shape, a rectangular shape, and a diamond shape. In some embodiments, the opening may be part of a non-cylindrical fluid passage. | 11-12-2015 |
20150367017 | PURIFIED AIR AND METHODS OF MAKING AND USING THE SAME - Purified air is provided, having a TVOC content of from less than 5 ppb to about 500 ppb, a Biologicals content of from less than 1 CFU/M | 12-24-2015 |
20160113680 | IVF EGG COLLECTION CHAMBER - The present invention relates to egg chambers for use in collection, inspection and selection of eggs for in vitro fertilisation (IVF) procedures. The egg chamber, in use, provides an effectively closed and fluid filled system which minimises the environmental changes that a harvested egg is exposed to, thus maximising viability. The egg chamber comprises a vessel which can be made airtight, comprising at least one side wall, an upper wall and a lower wall, at least a portion of the upper wall being transparent and at least a portion of the lower wall being light permeable; a first inlet with a sealable port; a first outlet with a sealable port; a filter with a pore size appropriate for egg collection disposed within the vessel between the first inlet and the first outlet and configured to separate the vessel into a first internal chamber and a second internal chamber. | 04-28-2016 |
20160115557 | METHODS AND COMPOSITIONS FOR GENETICALLY DETECTING IMPROVED MILK PRODUCTION TRAITS IN CATTLE - An isolated nucleic acid molecule comprising a polymorphic site selected from the group consisting of positions 164, 269, 284, 407 and 989 of SEQ ID NO: 1, an array or a kit comprising the same. Also provided are a method for detecting single nucleotide polymorphism (SNP) in bovine proteinase inhibitor (PI) gene, a method for haplotyping a bovine cell, a method for progeny testing of cattle based on said haplotyping, a method for selectively breeding of cattle based on haplotyping a parent animal. The present invention further provides a method for testing a dairy cattle for its milk production trait, comprising haplotyping its cells, wherein a cattle having haplotypes 1, 3, 4 or 5 indicates that the cattle has desirable milk production trait. Haplotype 1 indicates that the cattle has the most desirable milk production trait. | 04-28-2016 |
20160175283 | OXYTOCIN RECEPTOR ANTAGONIST THERAPY IN THE LUTEAL PHASE FOR IMPLANTATION AND PREGNANCY IN WOMEN UNDERGOING ASSISTED REPRODUCTIVE TECHNOLOGIES | 06-23-2016 |