| Entries |
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| 20080200819 | Orthostasis detection system and method - The disclosed embodiments relate to a system and method for monitoring patient data. An exemplary method comprises obtaining hemodynamic variation data that corresponds to a variation in intravascular hemodynamics of a patient, searching the hemodynamic variation data for an indication of orthostasis in response to the occurrence of a positional maneuver of or by the patient, and generating an output if the indication orthostasis is discovered. | 08-21-2008 |
| 20080200820 | System for determining endothelial dependent vasoactivity - A method of determining endothelial dependent vasoactivity of a subject, the method is effected by recording pressure-related signals of a plurality of locations adjacent to at least one blood vessel; extracting at least one parameter from the pressure-related signals; and using the at least one parameter to determine a change of at least one characteristic of the at least one blood vessel, the change being representative of endothelial functioning; thereby determining the endothelial dependent vasoactivity of the subject. | 08-21-2008 |
| 20080208064 | Method and apparatus for measuring blood pressure - A method and an apparatus for measuring blood pressure are disclosed. The method is applied to a blood pressure measurement apparatus and comprises the steps of providing a sensing unit for sensing a user's pulse, counting the pulse in a time interval by a counting unit based on the sensing unit to calculate a pulse rate, determining the condition of the pulse rate by a determination mechanism to generate an operation signal, controlling the blood pressure measurement apparatus based on the operation signal to determine whether or not the pulse rate is steady to ensure the accuracy of measuring the blood pressure. Therefore, the invention can improve the inaccuracy of the blood pressure measurement caused by human errors. | 08-28-2008 |
| 20080214941 | Blood Pressure Measuring Device and a Method for Operating a Blood Pressure Measuring Device - A blood pressure self-monitoring device includes an alarm generator to remind the patient to carry out blood pressure measurements according to a predetermined schedule. The device performs a specific phase of measuring blood pressure according to a clinically validated criterion, and calculates an accurate blood pressure reading on the basis of plural measurement values. The device also has a therapeutic decision mode, which can monitor blood pressure for assessing the effect of antihypertensive drug treatment. In the extended mode, the alarm generator works according to a predetermined daily measurement to remind the patient to take a blood pressure measurement following drug intake. Also during the treatment phase, the antihypertensive drug may affect the probability of irregular heartbeat, which can be a reference index for assessing the types and doses of treated antihypertensive drug. The device can also use a selectable switch to operate as a regular home blood pressure monitor. | 09-04-2008 |
| 20080214942 | APPARATUS AND METHOD FOR MEASURING BLOOD PRESSURE - Disclosed are an apparatus and method for measuring a blood pressure capable of enhancing accuracy and reliability for a blood pressure. According to the apparatus and method, a blood pressure is obtained by using a pulse transit time (PTT) calculated based on a pulse wave measured with a minimized error, a subject's body information, pulse analysis information, and environment information together measured when measuring the pulse wave. | 09-04-2008 |
| 20080221461 | VITAL SIGN MONITOR FOR CUFFLESSLY MEASURING BLOOD PRESSURE WITHOUT USING AN EXTERNAL CALIBRATION - The invention provides a method for measuring a patient's blood pressure featuring the following steps: 1) measuring a first time-dependent optical signal with a first optical sensor; 2) measuring a second time-dependent optical signal with a second optical sensor; 3) measuring a time-dependent electrical signal with an electrical sensor; 4) estimating the patient's arterial properties using either the first or second time-dependent optical signal; 5) determining a pulse transit time (PTT) from the time-dependent electrical signal and at least one of the first and second time-dependent optical signals; and 6) calculating a blood pressure value using a mathematical model that includes the PTT and the patient's arterial properties. | 09-11-2008 |
| 20080221462 | Detection of oximetry sensor sites based on waveform characteristics - In accordance with an embodiment of the present technique, there is provided methods and systems for detecting the location of a sensor and determining calibration algorithms and/or coefficients for calculation of physiological parameters based on the detected location. An exemplary embodiment includes receiving a signal corresponding to absorption of at least one wavelength of light by a patient's tissue, generating a plethysmographic waveform from the signal, determining an identifying characteristic of the plethysmographic waveform, and determining a location of the sensor based on a comparison of the identifying characteristic with at least one defined criterion. | 09-11-2008 |
| 20080228087 | PRESSURE MEASUREMENT DEVICE - A pressure measurement device isolates liquid, such as blood, from an intermediate fluid, such as air, by means of a diaphragm. The diaphragm is arranged between first and second chambers of respective first and second shells of a pressure pod body. The first shell has first and second ports, which are connected to the first chamber. The second shell has a measurement port with a connector in communication with the second chamber. A pressure transducer with a mating connector is directly connected to the measurement port connector to minimize the sealed volume between the diaphragm and the pressure transducer. | 09-18-2008 |
| 20080228088 | System and Method for Detecting and Predicting a Syncope Event - The present invention relates to a system ( | 09-18-2008 |
| 20080228089 | Method and apparatus for cufflessly and non-invasively measuring wrist blood pressure in association with communication device - A method of cufflessly and non-invasively measuring blood pressure in a wrist region of a patient in association with a communication device that relays the information being measured includes: detecting a magnitude difference between a plurality of pulse wave signals detected from a wrist of a user; detecting feature points from an electrocardiogram (ECG) and pulse wave signals detected from the user; extracting variables needed to calculate the highest blood pressure and the lowest blood pressure using the detected feature points; and calculating the highest blood pressure and the lowest blood pressure of the user by deducing a scatter diagram using the extracted variables. | 09-18-2008 |
| 20080243006 | METHOD AND APPARATUS FOR CONTINUOUS PULSE CONTOUR CARDIAC OUTPUT - A system and method are provided for sensing cardiac electrogram (EGM) signals and ventricular pressure signals and for using the sensed EGM and sensed pressure signals for estimating stroke volume (SV). A measure of cardiac output can be computed from the estimated SV and a heart rate determined from the EGM signals. The sensed ventricular pressure signal and the sensed EGM signal are used to derive landmark points such as an estimated pulmonary diastolic pressure, a mean pulmonary artery pressure, a peak right ventricular pressure (RVP), and various time intervals used in computing an area or a pulse contour integral. The pulse contour integral is used to estimate SV. The estimated pulmonary diastolic pressure, mean pulmonary artery pressure and CO computed from the estimated SV can be used to compute a pulmonary vascular resistance. | 10-02-2008 |
| 20080249422 | Method and system for improving physiologic status and health via assessment of the dynamic respiratory arterial pressure wave using plethysmographic technique - The present invention specifies a method and system for assessing the dynamic respiratory arterial pressure wave using plethysmographic sensing techniques. The dynamic respiratory arterial pressure wave is measured and plotted for purposes of diagnosis and or remedial biofeedback. | 10-09-2008 |
| 20080287811 | Method for Assessing The Functional Condition Of Cardiovascular System - The invention relates to medicine, namely: to cardiology, and may be used for assessment of functional condition of the human cardiovascular system (CVS) and the character of its control by the autonomic nervous system and other regulatory systems of the homeostasis. A method of non-invasive examination of the human CVS was developed, the method enabling to continuously, during a necessary period of time and quite simply with the aid of a computer and a piezoceramic tranducer (FIG. | 11-20-2008 |
| 20080287812 | Systems and Methods for Model-Based Estimation of Cardiac Output and Total Peripheral Resistance - The methods and systems for estimating cardiac output and total peripheral resistance include observing arterial blood pressure waveforms to determine intra-beat and inter-beat variability in arterial blood pressure and estimating from the variability a time constant for a lumped parameter beat-to-beat averaged Windkessel model of the arterial tree. Uncalibrated cardiac output and uncalibrated total peripheral resistance may then be calculated from the time constant. Calibrated cardiac output and calibrated total peripheral resistance may be computed using calibration data, assuming an arterial compliance that is either constant or dependent on mean arterial blood pressure. The parameters of the arterial compliance may be estimated in a least-squares manner. | 11-20-2008 |
| 20080300494 | REAL-TIME MEASUREMENT OF VENTRICULAR STROKE VOLUME VARIATIONS BY CONTINUOUS ARTERIAL PULSE CONTOUR ANALYSIS - Ventricular stroke volume variation (SVV) is estimated as a function of the standard deviation of arterial blood pressure value measured over each of at least two cardiac cycles, preferably over each of the cardiac cycles in a computation interval covering a full respiratory cycle. In one embodiment, maximum and minimum standard deviation values are determined over the computation interval. SVV is then estimated proportional to the ratio of the difference between the maximum and minimum standard deviation values and the mean of the standard deviation values. In another embodiment, SVV is then estimated proportional to the ratio of the standard deviation of the standard deviation values and the mean standard deviation over the entire computation interval. A pre-processing arrangement for improving reliability of estimates of more general cardiac or hemodynamic parameters is also disclosed and involves smoothing with an approximating function, and sampling and low-pass filtering at an adjustable rate. | 12-04-2008 |
| 20080306393 | Deriving Central Aortic Systolic Pressure and Analyzing Arterial Waveform Data to Derive Central Aortic Systolic Pressure Values - A method of deriving central aortic systolic pressure comprises (a) creating a set having a predetermined number of blood pressure measurements, the set representative of an arterial waveform; (b) determining an integer interval value; (c) averaging a series of consecutive blood pressure measurement readings in the set equal to the integer interval value commencing from the f | 12-11-2008 |
| 20080312542 | MULTI-SENSOR ARRAY FOR MEASURING BLOOD PRESSURE - A sensor for monitoring a patient's blood pressure, the sensor including a housing unit with a back surface and which includes: a pair of electrodes mounted on the back surface; an optical system mounted on the back surface and including at least one light source that emits optical radiation near 570 nm and at least one photodetector; a first amplifier which generates an analog electrical waveform from the electrical signals from the electrodes; a second amplifier that generates an analog optical waveform from the optical signal from the photodetector; analog-to-digital converter circuitry configured to receive the analog electrical waveform and generate a digital electrical waveform therefrom and to receive the analog optical waveform and generate a digital optical waveform therefrom; and a processor programmed to receive the digital electrical and optical waveforms and determine a pulse transit time for the patient which is a measure of a separation in time of a first feature of the digital electrical waveform and a second feature of the digital optical waveform and to use the pulse transit time to determine a blood pressure value for the patient. | 12-18-2008 |
| 20080319327 | BODY-WORN SENSOR FEATURING A LOW-POWER PROCESSOR AND MULTI-SENSOR ARRAY FOR MEASURING BLOOD PRESSURE - A system is described that continuously measures a patient's blood pressure over a length of time. The system features a sensor assembly featuring a flexible cable configured to wrap around a portion of a patient's arm. The flexible cable features a back surface that includes at least two electrodes that are positioned to contact the patient's skin to generate electrical signals. It additionally features an optical sensor that includes at least one light source and at least one photodetector. These components form an optical sensor that is configured to generate an optical signal by detecting optical radiation emitted by the at least one light source and reflected from a blood vessel underneath the patient's skin. | 12-25-2008 |
| 20090012409 | Determining Blood Pressure - A method and a measuring device for determining blood pressure, pressure signals being detected using a pressure sensor which may be applied to a body part, such as a wrist. The blood pressure is determined by an analysis unit, analyzing the pressure signals and considering signals from an orientation detection unit detecting the position and/or movement and/or acceleration of the body part. | 01-08-2009 |
| 20090030328 | METHOD OF ESTIMATING PULSE WAVE VELOCITY - A method of estimating blood pressure Pulse Wave Velocity (PWV) in the aorta from a recording of a pressure waveform at a single site. The method comprises the following steps: 1. measuring the patient's arterial pressure relative to time in order to estimate a central pressure waveform (CPW); 2. estimating the patient's aortic pressure pulse transit time (PPTT) from the CPW; 3. estimating the patient's carotid to femoral arterial distance from the patient's physical characteristics; and 4. dividing the patient's estimated carotid to femoral arterial distance by the patient's estimated PPTT to estimate the patient's PWV. | 01-29-2009 |
| 20090043213 | LOAD INDEPENDENT INDEX OF DIASTOLIC FUNCTION - Methods and related apparatus and systems for determining a load-independent index of diastolic function in the heart are described. | 02-12-2009 |
| 20090054793 | Cardiac pressure monitoring device - A cardiac pressure monitoring device includes a fixation member defining a central opening to facilitate slidably positioning the fixation device about a pacemaker lead wire. At least one sensor is coupled to the fixation member. The at least one sensor is configured to sense a physical, chemical, and/or physiological parameter within a cardiac chamber. | 02-26-2009 |
| 20090062663 | NON-INVASIVE BLOOD PRESSURE MONITOR APPARATUS AND SYSTEM - A non-invasive blood pressure monitoring system is disclosed herein. The non-invasive blood pressure monitoring system includes a pressure cuff comprising a resistive portion and a conductive portion aligned with the resistive portion. The non-invasive blood pressure monitoring system also includes a controller operatively connected to the pressure cuff. The controller is adapted to estimate the circumference of the pressure cuff based on the position of the conductive portion relative to the resistive portion. | 03-05-2009 |
| 20090062664 | BLOOD PRESSURE MEASUREMENT DEVICE - A blood pressure measurement device. The device comprises a measurement component for measuring blood pressure and a display component for displaying the blood pressure data measured. The display component is adapted to display simultaneously at least two sets of blood pressure measurement data measured at different date or time. Alternatively, the device further comprises a measurement state control component for recording and storing at least one measurement state related to the measurement of the blood pressure, and means for providing the at least one measurement state. Alternatively, the device further comprises an interfacing component that comprises a bi-direction multifunctional port, for exchanging blood pressure data measured between the blood pressure measurement device and at least one external device. | 03-05-2009 |
| 20090062665 | NONINVASIVE METHOD AND APPARATUS FOR MEASURING BLOOD PRESSURE BY DETERMINING A MAXIMUM FREQUENCY OF SPECTRAL CONTENT OF THE SECOND HEART SOUND - Methods and apparatus for noninvasively estimating a blood pressure are provided. A bandpass filter is applied to a second heart sound (S2) component to generate a filtered S2 component. The bandpass filter has a lower cutoff frequency greater than a maximum frequency of the S2 component. The maximum frequency of the S2 component is estimated using the filtered S2 component, a predetermined relationship is applied between the estimated maximum frequency and blood pressure to generate a blood pressure estimate and the blood pressure estimate is displayed. | 03-05-2009 |
| 20090062666 | Arterial pressure-based, automatic determination of a cardiovascular parameter - One or more cardiovascular parameters is estimated as a function of the arterial pressure waveform, in particular, using at least one statistical moment of a discrete representation pressure waveform having an order greater than one. Arterial compliance, the exponential pressure decay constant, vascular resistance, cardiac output, and stroke volume are examples of cardiovascular parameters that can be estimated using various aspects of the invention. In one embodiment of the invention, not only are the first four moments (mean, standard deviation, skewness, and kurtosis) of the pressure waveform used to estimate the cardiovascular parameter(s) of interest, but also heart rate, statistical moments of a set of pressure-weighted time values, and certain anthropometric patient measurements such as age, sex, body surface area, etc. | 03-05-2009 |
| 20090069698 | BLOOD PRESSURE MEASURING APPARATUS AND METHOD OF MEASURING BLOOD PRESSURE - Provided is a blood pressure measuring apparatus and a method of measuring blood pressure. The blood pressure measuring apparatus includes a plurality of blood pressure measuring units disposed on a substrate, a plurality of optical sensors disposed on the substrate to correspond to the blood pressure measuring units, and a control unit that measures blood pressure by analyzing signals received from the optical sensors and the blood pressure measuring units, wherein each of the blood pressure measuring units comprises a plurality of blood pressure sensors. | 03-12-2009 |
| 20090069699 | Method of measuring instantaneous arterial blood pressure and compliance and device thereof - A method of measuring the instantaneous arterial blood pressure and compliance and the device thereof are disclosed. The method identifies a critical depth under the skin. At this critical position, the arterial mean blood pressure is equivalent to the mean blood pressure obtained on the skin. The variation in the arterial mean blood pressure is tracked and controlled to maintain the equivalence between the mean blood pressure measured on the skin and the arterial mean blood pressure. In this case, the compliance of the muscle tissues remains invariant. Therefore, the variation measured on the skin is simply the behavior of the blood vessel. Using the skin-artery correlation, the invention can obtain the instantaneous blood pressure after some computation and the dynamic compliance at the critical position. | 03-12-2009 |
| 20090069700 | Method for processing of continuous pressure-related signals derivable from locations inside or outside a human body or body cavity - This invention describes a method for processing pressure signals derivable from locations inside or outside a human or animal body or body cavity. Different aspects of the invention relate to a method for optimal differentiating between cardiac beat- and artifact-induced pressure waves, a method for obtaining new and improved information from said pressure signals. In particular, this invention describes the use of said inventive method for processing of pressure signals for controlling an adjustable shunt valve. The method can be incorporated in a processing unit of a device for use in draining fluid from a brain or spinal fluid cavity. | 03-12-2009 |
| 20090082677 | EXERCISE ASSISTING DEVICES - An exercise assisting device comprising a detector configured to detect at least one physiological data of a user, a control module configured to convert the at least one physiological data into at least one index in accordance with an algorithm, each of the at least one index being representative of an exercise performance level, a memory module including a first section configured to store a number of predetermined data related to a number of exercise performance levels, a second section configured to store the at least one index, and a third section configured to store the algorithm, and a display module configured to display at least one of the number of predetermined data in accordance with the at least one index. | 03-26-2009 |
| 20090099463 | SYSTEM AND METHOD FOR A NON-SUPINE EXTREMITY BLOOD PRESSURE RATIO EXAMINATION - The present invention provides apparatuses and methods that facilitate the determination of a hydrostatic correction factor usable in an EBPR examination of a patient in a non-supine position. In one embodiment, a first blood pressure measuring device may be positionable on a first extremity of the patient, and a second blood pressure measuring device may be positionable on a second extremity of the patient, with one of the blood pressure measuring devices being located above the other one. The apparatus includes a locating mechanism that fixes a position of at least one of the first and second blood pressure measuring devices relative to its respective patient extremity. The apparatus also includes an instrumentality that provides information about a vertical distance between the first and second blood pressure measuring devices. The vertical distance is usable in determining the hydrostatic correction factor. | 04-16-2009 |
| 20090112102 | Therapy device with a time-variable blood regulation - A therapy device having a blood pressure device and a regulating device for a time-variable regulation of the blood pressure, which decides, during a therapy procedure, dependent on detected blood pressure value, whether the blood regulation is continued with hypothetical or with real blood pressure values. The regulating device processes various categories of blood pressure values, i.e. blood pressure values obtained by the regulating device according to an implemented time schedule, blood pressure values requested by measurement and evaluation device, and blood pressure values requested by medical staff. Besides the regular triggers (RT) generated at regular intervals, the irregular triggers (IRT) and the quasi-regular triggers (QRT) requested externally at respective times are also evaluated. | 04-30-2009 |
| 20090124910 | Method for processing of continuous pressure-related signals derivable from a human or animal body or body-cavity - This invention describes a method for processing pressure signals derivable from locations inside or outside a human or animal body or body cavity. Different aspects of the invention relate to a method for optimal differentiating between cardiac beat- and artifact-induced pressure waves, a method for obtaining new and improved information from said pressure signals, a method for obtaining signals predicting pressures inside a body or body cavity from pressure signals outside said body or body cavity. In particular, this invention describes a method for modifying individual continuous non-invasive pressure-related signals into signals highly predictable of the corresponding invasive pressure-related signals based on already established relationships that can be used for formula-based adjustments of individual signals solely obtained by a non-invasive approach. | 05-14-2009 |
| 20090131804 | Method And Apparatus For Determining Central Aortic Pressure Waveform - A method is provided for determining a central aortic pressure waveform. The method includes: measuring two or more peripheral artery pressure waveforms; analyzing the signals so as to extract common features in the measured waveforms; and determining an absolute central aortic pressure waveform based on the common features. | 05-21-2009 |
| 20090131805 | Patient Monitoring - A hemodynamic monitor and corresponding method for determining the requirement for, and if required the nature or extent of, and for monitoring the response to, an intervention by a carer for a subject in order to improve the hydration level and hemodynamic status of the subject during a period or periods of hemodynamic instability includes, firstly, a processor. The processor incorporates software arranged to continuously analyse and process a blood pressure or arterial volume/plethysmographic signal obtained from the subject in order to derive a plurality of complementary parameters throughout the monitoring of the subject. The monitor also incorporates display means displaying images representing the derived plurality of complementary parameters. The images may include at least one image representing graphically at least one stress related hemodynamic parameter plotted against time to provide an immediate indication of a change in hemodynamic status and thus the requirement for an intervention. The images may also include at least one image representing graphically at least one fluid responsiveness parameter plotted against time to provide an indication of the hydration level and associated ventricular pre load status of the subject to determine the nature or extent of the intervention if required. Respiratory variations in fluid responsiveness parameters may usefully be displayed. The images may also include at least one image representing graphically at least one response related parameter compared to the value of the parameter at the point of the intervention to provide an indication of the desired and/or actual response of the subject to an intervention. Trend and acute changes displays may be combined. Specific parameters providing information on the quality of the left ventricle and right heart/venous return/preload may also be derived and displayed. | 05-21-2009 |
| 20090131806 | Apparatus and methods for non-invasively measuring a patient's arterial blood pressure - Improved apparatus and methods for non-invasively assessing one or more hemodynamic parameters associated with the circulatory system of a living organism. In one aspect, the invention comprises an apparatus adapted to automatically and accurately place and maintain a sensor (e.g., tonometric pressure sensor) with respect to the anatomy of the subject. The apparatus comprised of a sensor device removably coupled to an actuator which is used to position the sensor during measurements. Methods for positioning the alignment apparatus and sensor, and operating the apparatus, are also disclosed. | 05-21-2009 |
| 20090137912 | Blood Pressure Measurement Apparatus - A blood pressure measurement apparatus includes: a detector, operable to detect a first pulse, a second pulse prior to the first pulse and a third pulse prior to the second pulse under the same pressure; a first distinguisher, operable to distinguish whether waveforms of the first and second pulses are substantially identical with each other; a second distinguisher, when the waveforms are not substantially identical with each other, operable to distinguish whether parameters of the first, second and third pulses meet a condition corresponding to arrhythmia; a determiner, operable to determine the first and second pulses to be pulse waves when the waveforms are substantially identical with each other, and operable to determine the first, second and third pulses to be pulse waves when the parameters meet the condition; and a calculator, operable to calculate a blood pressure value based on the pulse waves. | 05-28-2009 |
| 20090143687 | DEVICE AND METHOD FOR MANAGING, ARCHIVING AND/OR EVALUATING BLOOD PRESSURE DATA - A device and method for managing, archiving and/or evaluating blood pressure data of a plurality of patients. The blood pressure data is acquired using blood pressure monitors. The blood pressure data for each patient is separately stored in an individual storage space in a central data server. A network connection including at least one network terminal is used to input the data into the individual storage space and read out the data from the individual storage space. A control device controls access to the storage spaces by comparing a transmitted access code including a unique device identification code for the blood pressure monitor of the patient corresponding to the individual storage space with a unique access code corresponding to the individual storage space. | 06-04-2009 |
| 20090149762 | Apparatus for displaying the blood pressure value and method thereof - An apparatus for displaying the blood pressure and a method thereof are disclosed. The apparatus uses a blood-measuring unit for receiving an analog blood pressure signal; a photoplethysmography (PPG) signal measuring unit for receiving an analog PPG signal; an analog-to-digital converter for converting the analog blood pressure signal into a digital blood pressure signal and the analog PPG signal into a digital PPG signal; an input unit for generating a human data; a microprocessor unit for receiving the digital blood pressure signal, the digital PPG signal and the human data so as to generate a different value in response to the digital blood pressure signal and the digital PPG signal, and output a pulse wave velocity (PWV) signal in response to the operation of the different value and the human data; an LCD driving unit for outputting an first LCD driving voltage and a second LCD driving voltage respectively in response to the digital blood pressure signal and the pulse wave velocity (PWV) signal; an LCD unit for displaying the colors that correspond to the first LCD driving and the second LCD driving voltage respectively. | 06-11-2009 |
| 20090182238 | Method of predicting a blood pressure trend by blood pressure measurements - The present invention discloses a method of predicting a blood pressure trend by blood pressure measurements, and the method allows users to select a number of times for measuring blood pressures as a cycle according to a doctor's recommendation or a personal preference, and automatically calculates and stores an average of blood pressures of the cycle (including systolic and diastolic blood pressures). With the variation of average blood pressures of previous and next cycles, users can know about the variation of the trends of their systolic and diastolic blood pressures quickly and easily. The trend of blood pressures is provided as a reference for users to adjust their living habits and for medical professionals to diagnose a patient's condition in hope of resuming the normal blood pressure of the patient. | 07-16-2009 |
| 20090192392 | Method, system, and apparatus for statistical evaluation of antihypertensive treatment - A novel method, system, and apparatus—the RDH Method—for evaluating antihypertensive treatment efficacy across patient populations is disclosed. In accordance to one embodiment, the RDH is a population vector index and graphical method that provides the means for the statistical assessment of antihypertensive treatment reduction, duration, and homogeneity using ambulatory blood pressure monitoring (ABPM). The population RDH was specifically designed as a tool to evaluate and compare blood pressure (BP) coverage offered by antihypertensive drugs over 24 h in populations. In accordance to one embodiment, the population RDH is a three-component vector index that incorporates information about the reduction, duration, and homogeneity of antihypertensive treatment, as well as their statistical significance over the 24 h period. In the preferred embodiment, the population RDH components quantify: 1) the total number of statistical significant BP reductions, 2) the maximum number of consecutive statistical significant reductions, and 3) the maximum number of consecutive non-significant reductions over the 24 hours, respectively; and reports two population graphs that characterize the effect of the treatment. The output of the RDH index can be used in clinical trials to characterize the effects of antihypertensive medications, and in clinical practice to guide antihypertensive treatment. | 07-30-2009 |
| 20090198140 | METHOD AND APPARATUS FOR EVALUATION OF FLUID RESPONSIVENESS - The present invention discloses a method and related apparatus for determining a cardiac parameter from either the arterial blood pressure signal or the photoplethysmographic signal to quantify the degree of amplitude modulation due to respiration (pulse pressure variation) and predict fluid responsiveness. The method involves the application of Lempel-Ziv complexity to a filtered and segmented physiologic signal for direct determination of the fluid status of a patient. Real-time monitoring of fluid status involves the implementation of the disclosed method as part of a bedside monitoring apparatus. | 08-06-2009 |
| 20090209868 | Adaptive Frequency Domain Filtering for Improved Non-Invasive Blood Pressure Estimation - A system for processing oscillometric data from a plurality of pressure steps to determine the blood pressure of a patient as disclosed herein. A heart rate monitor connected to the patient acquires the patient's heart rate. A time to frequency domain converter receives oscillometric data and converts the oscillometric data into the frequency domain. A harmonic frequency calculator is connected to the heart rate monitor and derives at least the heart rate fundamental frequency. A filter connected to the time to frequency domain converter and the harmonic frequency calculator that produces a filter frequency domain oscillometric signal. A reconstruction calculator receives the filtered frequency domain oscillometric signal and reconstructs a time domain oscillometric signal. A method of computing an oscillometric envelope for use in determining the blood pressure of a patient is also disclosed herein. | 08-20-2009 |
| 20090216132 | System for Continuous Blood Pressure Monitoring - The invention provides a system and method for monitoring blood pressure. The system includes a cuff-free non-invasive portable blood pressure monitoring device, a processor configured to process in real-time signals obtained by the portable blood pressure device to produce one or more processing products, and a portable monitor having a display displaying in real-time one or more of the processing products. In the method of the invention, a blood pressure signal is obtained from a cuff-free non-invasive portable blood pressure monitoring device. Signals obtained by the portable blood pressure device are processed in real-time to produce one or more processing products that are displayed in real-time on a display of a portable monitor. The method and system of the invention may be used in the management of hypertension. | 08-27-2009 |
| 20090216133 | SYSTEMS AND METHODS FOR DETERMINING VESSEL COMPLIANCE - The disclosure of the present application provides for systems and methods for determining a phasic change in a vessel and vessel compliance. In at least one exemplary method for determining a phasic change in a vessel, the method comprises the steps of introducing a device into a site within a vessel, operating the device in connection with two or more fluid injections in the vessel to obtain two or more conductance values, calculating a parallel conductance value and a total conductance value, and calculating a phasic change in at least one vessel parameter based in part upon the calculated parallel conductance value and the calculated total conductance value. In an exemplary method for determining vessel compliance, the method comprises, in part, the steps of calculating a first vessel parameter and a second vessel parameter based on at least two conductance values, calculating a change in vessel parameter based upon the first and second vessel parameters, and calculating vessel compliance based upon the relationship between the change in vessel parameter and a change in pressure during a cardiac cycle. | 08-27-2009 |
| 20090270739 | REAL-TIME DETECTION OF VASCULAR CONDITIONS OF A SUBJECT USING ARTERIAL PRESSURE WAVEFORM ANALYSIS - Methods for the detection of vascular conditions such as vasodilation in a subject are described. The methods involve receiving a signal corresponding to an arterial blood pressure and calculating one or more cardiovascular parameters from the arterial blood pressure. The cardiovascular parameters are calculated using factors impacted by vascular conditions such as vasodilation. Factors impacted by these vascular conditions include the area under the systolic portion of the arterial blood pressure signal, the duration of systole, and the ratio of the duration of the systole to the duration of the diastole. By monitoring cardiovascular parameters that are calculated using factors impacted by vascular conditions such as vasodilation for changes indicating the vascular conditions, such vascular conditions can be detected. | 10-29-2009 |
| 20090281434 | PERSONALIZED FLUID ASSESSMENT - A system and method of monitoring the fluid status of a patient. The system may include a patient monitor that receives blood pressure data. A first fluid model receives the blood pressure data, and a personalized fluid model is derived from the application of the blood pressure data to the first fluid model. An estimation of the patient's fluid status may be derived from the personalized fluid model. The method may include the steps of measuring a first blood pressure value, creating a personalized fluid model, measuring a second blood pressure value, applying the second blood pressure value to the personalized fluid model; and deriving an estimation of the fluid status of the patient. | 11-12-2009 |
| 20090287095 | Method for Determining Cardiac Output - In a method for determining cardiac output from an arterial blood pressure curve measured at the periphery, in which the blood pressure curve measured at the periphery is arithmetically transformed into the corresponding central blood pressure curve and the cardiac output is calculated from the central blood pressure curve, the transformation of the blood pressure curve measured at the periphery into the corresponding central blood pressure curve is performed by the aid of an artificial neural network whose weighting values are determined by learning. | 11-19-2009 |
| 20090299197 | Remote Blood Pressure Waveform Sensing Method and Apparatus - The invention as disclosed is a non-contact method and apparatus for continuously monitoring a physiological event in a human or animal, such as blood pressure, which involves utilizing a laser-based interferometer system in combination with a laser tracking system and a signal processor to produce a waveform that is representative of a continuous physiological event such as blood pressure or respiration in a subject. | 12-03-2009 |
| 20090306524 | SENSOR FOR DETECTING THE PASSING OF A PULSE WAVE FROM A SUBJECT'S ARTERIAL SYSTEM - In order to provide an easy-to-use technique for measuring blood pressure and/or other vital signs of a subject, a sensor for detecting the passing of a pulse wave from a subject's arterial system is suggested, the sensor being adapted to be located at a sensing position on the exterior of the subject's body, characterized in that the sensor comprises a number of electrical coils for generating an inductive coupling to the subject's body in a way that the properties of said inductive coupling change if a pulse wave passes a screened volume underneath the sensing position, and a circuit connected to the number of electrical coils, said circuit being adapted to detect said property changes of the inductive coupling. | 12-10-2009 |
| 20090326389 | Medical Therapy Device - A system and a method for synchronizing operation between a patient monitoring device and a patient treatment device are disclosed. The patient monitoring device and the patient treatment device are operatively connected via a network, for example, a patient area network (PAN) or a local area network (LAN). A controller with a display is configured to accept user input via a graphic user interface (GUI) and display a patient's physiological data and operating parameters of both the patient monitoring device and the patient treatment device. The operation is synchronized by starting to operate the patient monitoring device at a predetermined operating state of the patient treatment device, and delaying changes in the operating state of the patient treatment device, until the operation of the monitoring device is concluded or the operating state of the patient treatment device indicates an abort condition. | 12-31-2009 |
| 20100004546 | FINGER ARTERIAL ELASTICITY MEASURING PROGRAM, FINGER ARTERIAL ELASTICITY MEASURING DEVICE AND FINGER ARTERIAL ELASTICITY MESAURING METHOD - PROBLEMS TO BE SOLVED: A finger arterial elasticity measuring program, a finger arterial elasticity measuring device and a finger arterial elasticity measuring method are provided for making it possible to measure an elasticity index of a finger artery in accordance with a pulse wave of a finger artery without measuring a blood pressure in evaluating the elasticity of the finger artery related to the degree of arterial sclerosis in an easy and least expensive manner. | 01-07-2010 |
| 20100016734 | Systems and Methods Using Induced Perturbation to Determine Physiological Parameters - According to embodiments, systems and methods for non-invasive blood pressure monitoring are disclosed. An exciter may induce perturbations in a subject, and a sensor or probe may be used to obtain a detected signal from the subject. The detected signal may then be used to measure one or more physiological parameters of the patient. For example if the perturbations are based on a known signal, any differences between the known signal and the input signal may be attributable to the patient's physiological parameters. A phase drift between the perturbation signal and the detected signal may be determined from a comparison of the scalograms of the exciter location and the sensor or probe location. From the scalogram comparison, more accurate and reliable physiological parameters may be determined. | 01-21-2010 |
| 20100016735 | METHOD FOR DETERMINATION OF CARDIAC OUTPUT - A method for determination of cardiac output from a recording of an arterial pressure waveform ( | 01-21-2010 |
| 20100016736 | Estimating Aortic Blood Pressure from Non-Invasive Extremity Blood Pressure - Methods and a computer program product for using a circulatory measurement on an extremity of a particular subject to derive an aortic blood pressure for that subject. A model is constructed that maps a peripheral cardiovascular waveform to a central cardiovascular waveform on the basis of a plurality of model parameters. A time record is obtained using a non-invasive blood pressure sensor disposed at a solitary position periphery of the cardiovascular system of a subject. The time record is then transformed to obtain a plurality of test central blood pressure waves, with a single test central blood pressure wave is based on each of a plurality of sets of values of the model parameters. An optimum set of values of the model parameters is then selected, based on a specified criterion applied to the plurality of test central blood pressure waves, so that the aortic circulatory waveform of the subject can be obtained. | 01-21-2010 |
| 20100022895 | DIAGNOSIS SYSTEM OF DEFICIENT AND FORCEFUL PULSE - Disclosed herein is a system for diagnosing a deficient pulse and an forceful pulse. The system includes a pulse diagnotic device, a deficient pulse and forceful pulse determining device, and an output device. The pulse diagnotic device measures pulse condition information at an examinee's Cun (˜\f˜) Gu (H), and Chi (,R) pulse-taking locations on his or her wrist using one or more pulse-taking sensors. The deficient pulse and forceful pulse determining device is operably connected to the pulse diagnotic device, analyzes the pulse pressure information measured by the pulse diagnotic device, calculates a quantified deficiency/forceful coefficient, and determines whether a pulse of interest is a deficient pulse or an forceful pulse. The output device is connected to the determining device and displays results of the determination. | 01-28-2010 |
| 20100030086 | MONITORING HEMODYNAMIC STATUS BASED ON INTRACARDIAC OR VASCULAR IMPEDANCE - This disclosure relates to monitoring intracardiac or vascular impedance to determine a change in hemodynamic status by detecting changes in an impedance parameter over cardiac cycles. An example method includes measuring a plurality of impedance values of a path within a patient over time, wherein the path includes at least one blood vessel or cardiac chamber of the patient, and wherein the impedance values vary as a function of blood pressure within the at least one vessel or chamber, determining a plurality of values of an impedance parameter over time based on the measured impedance values, wherein each of the impedance parameter values is determined based on a respective sub-plurality of the impedance values, comparing at least one of the impedance parameter values to at least one prior impedance parameter value, and identifying a change in a cardiovascular parameter related to the blood pressure based on the comparison. | 02-04-2010 |
| 20100030087 | ESTIMATING CARDIOVASCULAR PRESSURE AND VOLUME USING IMPEDANCE MEASUREMENTS - Techniques for estimating a cardiac chamber or vascular pressure based upon impedance are described. A device or system may measure an impedance between at least two electrodes implanted within or proximate to a cardiovascular system. The device or system may estimate a pressure of an element of the cardiovascular system based on a relationship between impedance and volume of the element, and based on a empirical relationship between the volume and the pressure. The device or system may also estimate the dimension of the element based on the impedance-volume relationship, or other characteristics based on the impedance. Because the impedance measurements may be obtained, in some examples, by using electrodes and leads implanted within the cardiovascular system and coupled to an implantable medical device, a practical estimation of a cardiovascular pressure can be obtained on a chronic basis without requiring the use other invasive sensors, such as micronanometer transducers. | 02-04-2010 |
| 20100049059 | APPARATUS AND METHOD FOR MEASURING BLOOD PRESSURE - Disclosed are blood pressure measuring apparatus and method, in which a blood pressure measuring posture of a person to be examined is calculated on the basis of signals that are measured by an inclination measuring unit, so as to guide the person to be examined to maintain a reference measuring posture. When it is confirmed that the person to be examined maintains the reference measuring posture, blood pressure is measured on the basis of a measured living body signal of the person to be examined. By this disclosure, since the blood pressure measuring posture of the person to be examined can be correctly guided by inclination sensors, the person to be examined can accurately measure the blood pressure using a noninvasive and a nonpressurized method. | 02-25-2010 |
| 20100056930 | RAPID NON-INVASIVE BLOOD PRESSURE MEASURING DEVICE - A measurement device for generating an arterial volume-indicative signal includes an exciter and a detector. The exciter is adapted to receive an oscillating signal and generate a pressure wave based at least in part on the oscillating signal on the artery at a measurement site on a patient. The pressure wave includes a frequency. The detector is placed sufficiently near the measurement site to detect a volumetric signal indicative of arterial volume of the patient. | 03-04-2010 |
| 20100063405 | SYSTEMS, DEVICES AND METHODS FOR NONINVASIVE OR MINIMALLY-INVASIVE ESTIMATION OF INTRACRANIAL PRESSURE AND CEREBROVASCULAR AUTOREGULATION - The systems, devices, and methods described herein provide for the estimation and monitoring of cerebrovascular system properties and intracranial pressure (ICP) from one or more measurements or measured signals. These measured signals may include central or peripheral arterial blood pressure (ABP), and cerebral blood flow (CBF) or cerebral blood flow velocity (CBFV). The measured signals may be acquired noninvasively or minimally-invasively. The measured signals may be used to estimate parameters and variables of a computational model that is representative of the physiological relationships among the cerebral flows and pressures. The computational model may include at least one resistive element, at least one compliance element, and a representation of ICP. | 03-11-2010 |
| 20100076326 | METHOD FOR ESTIMATING CHANGES OF CARDIOVASCULAR INDICES USING PERIPHEAL ARTERIAL BLOOD PRESSURE WAVEFORM - The systems and methods described herein enable reliable estimation of cardiovascular indices on real-time, non-invasive or minimally-invasive, and beat-to-beat basis. Cardiovascular indices which can be estimated include), stroke volume (SV), without being limited to, cardiac output (CO and total peripheral resistance (TPR). In various embodiments, one or more of these indices are estimated continuously, on a beat-to-beat basis, using peripheral arterial blood pressure (ABP) waveforms and certain parameters derived from the peripheral ABP waveforms. The derived parameters are substantially insensitive to distortions of the ABP waveform arising from tapered arterial branches throughout the arterial tree. The methods described herein can provide a more accurate and reliable estimate of hemodynamic parameters than existing techniques. | 03-25-2010 |
| 20100081944 | Systems and Methods for Recalibrating a Non-Invasive Blood Pressure Monitor - Techniques for non-invasive blood pressure monitoring are disclosed. Data corresponding to a patient may be received from a hospital information system. The data may include, for example, drug administration data, medical procedure data, medical equipment data, or a combination thereof. Whether a blood pressure monitoring system needs to be recalibrated may be determined, based at least in part on the received data. If it is determined that the blood pressure monitoring system needs to be recalibrated, the recalibration may be performed and at least one blood pressure measurement of the patient may be computed using the recalibrated blood pressure monitoring system. | 04-01-2010 |
| 20100081945 | Systems and Methods for Maintaining Blood Pressure Monitor Calibration - Systems and methods are disclosed herein for maintaining the calibration of non-invasive blood pressure monitoring devices. Phase components of pulse signals detected by the blood pressure monitoring device are compared to stored baseline phase component values. If the difference exceeds a threshold, the blood pressure monitoring device is recalibrated. | 04-01-2010 |
| 20100081946 | METHOD AND APPARATUS FOR NON-INVASIVE CUFF-LESS BLOOD PRESSURE ESTIMATION USING PULSE ARRIVAL TIME AND HEART RATE WITH ADAPTIVE CALIBRATION - Certain aspects of the present disclosure relate to a method for estimating a blood pressure using both a pulse arrival time (PAT) and an instantaneous heart rate (HR). The PAT can be measured as the delay between QRS peaks in an electrocardiogram (ECG) signal and corresponding points in a photoplethysmogram (PPG) waveform. Parameters of the estimation model can be determined through an initial training. Then, the model parameters can be recalibrated in constant intervals using the recursive least square (RLS) approach combined with a smooth bias fixing. The proposed estimation algorithm is applied on a multi-parameter intelligent monitoring for intensive care (MIMIC) database, and the results are compared with estimation methods that use PAT only or HR only. The proposed estimation algorithm meets, on average, the Association for the Advancement of Medical Instrumentation (AAMI) requirements and outperforms other methods from the prior art. It is also shown in the present disclosure that the proposed estimation algorithm is robust to unknown skew between the ECG and PPG signals. | 04-01-2010 |
| 20100087743 | Pulse Contour Method and Apparatus for Continuous Assessment of a Cardiovascular Parameter - A cardiovascular parameter such as cardiac output is estimated from a current pressure waveform data set without needing to directly measure blood flow or arterial compliance. The general shape of an input flow waveform over one beat-to-beat cycle is assumed (or computed), and then the parameters of a flow-to-pressure model, if not pre-determined, are determined using system identification techniques. In one embodiment, the parameters thus determined are used to estimate a current peripheral resistance, which is used not only to compute an estimate of the cardiovascular parameter, but also to adjust the shape of the input flow waveform assumed during at least one subsequent beat-to-beat cycle. Another embodiment does not require computation of the peripheral resistance and still another embodiment computes a flow estimate from an optimized identification of the parameters defining the assumed input flow waveform. | 04-08-2010 |
| 20100094140 | Noninvasive Method and Apparatus to Measure Body Pressure Using Extrinsic Perturbation - Current noninvasive blood pressure measurement methods are not able to measure pressure during nonpulsatile blood flow. We propose method to measure intravascular or other compartment pressure which applies extrinsic pressure oscillation. Pressure-volume response of the compressed structure is obtained and compartment pressure is estimated as the extrinsic pressure at which compressed structure has the highest compliance. Delivering extrinsic oscillations at a higher frequency than the pulse rate, pressure reading can be obtained much faster. Because it is not dependant on intrinsic vascular oscillations, pressure can be measured during arrhythmias, during cardiac bypass, during resuscitation, in the venous compartment or in the other nonpulsatile compressible body compartments. | 04-15-2010 |
| 20100094141 | JUGULAR VENOUS PRESSURE RULER - A JVP ruler and a method for its use in measuring a jugular venous pressure in a patient, includes orienting the JVP ruler such that the second arm is collinear with a vertical line originating at a right atrium of the patient and such a the first arm is horizontal and having a transducer end situated opposite the pivot end of the first arm. The JVP Ruler has first and second arms elongate and situated to be in perpendicular relation one to the other. The arms meet and terminate at a pivot located at the pivot ends of the arms respectively, the transducer end being generally above a pulse point, the pulse point being a point on the skin of the patient where variations of the jugular venous pressure within the internal jugular vein are exhibited as at least vertical displacement of the skin. | 04-15-2010 |
| 20100094142 | Display Module of LED Light Pillar of Hemomanometer and the Hemomanometer with LED Light Pillar - The present invention relates to an instrument for measuring blood pressure. More particularly, the present invention relates to a display module of LED light pillar of hemomanometer. Which comprises a shell ( | 04-15-2010 |
| 20100099993 | METHODS AND APPARATUS FOR DETERMINING CARDIAC OUTPUT AND LEFT ATRIAL PRESSURE - Method and apparatus are introduced for determining proportional cardiac output (CO), absolute left atrial pressure (LAP), and/or other important hemodynamic variables from a contour of a circulatory pressure waveform or related signal. Certain embodiments of the invention provided herein include the mathematical analysis of a pulmonary artery pressure (PAP) waveform or a right ventricular pressure (RVP) waveform in order to determine beat-to-beat or time-averaged proportional CO, proportional pulmonary vascular resistance (PVR), and/or LAP. The invention permits continuous and automatic monitoring of critical hemodynamic variables with a level of invasiveness suitable for routine clinical application. The invention may be utilized, for example, to continuously monitor critically ill patients with pulmonary artery catheters installed and chronically monitor heart failure patients instrumented with implanted devices for measuring RVP. | 04-22-2010 |
| 20100121204 | BLOOD VESSEL STATE EVALUATING DEVICE, BLOOD VESSEL STATE EVALUATING METHOD, AND COMPUTER-READABLE RECORDING MEDIUM STORING BLOOD VESSEL STATE EVALUATING PROGRAM - A phase line tilt calculating unit (actual measurement) receives phase characteristics Pa(f) and Pb(f) outputted from frequency conversion units, and calculates phase difference characteristics of actual measurement based on a phase difference on each frequency component between the phase characteristics. A phase line tilt calculating unit (model) calculates phase difference characteristics between a transfer function Ga(f) and a transfer function Gb(f) calculated by a transfer function calculating unit, and outputs the calculated phase difference characteristics to a search unit. The search unit fits a variable k and determines a variable k | 05-13-2010 |
| 20100125211 | ASSESSMENT OF PULMONARY VASCULAR RESISTANCE VIA PULMONARY ARTERY PRESSURE - Methods and systems for assessing pulmonary or systemic vascular resistance in a patient using pressure measurements are disclosed. An illustrative method of measuring pulmonary vascular resistance includes electrically inducing a retrograde pressure pulse within the heart, sensing at least one arterial pressure parameter in response to the retrograde pressure pulse using a pressure sensor located within a pulmonary artery, and computing a value of the pulmonary vascular resistance using the at least one sensed arterial pressure parameter. Data from multiple pulmonary vascular resistance assessments can be taken over an extended period of time within the patient to aid in detecting an underlying cardiac or pulmonary condition such as cardiogenic pulmonary edema. | 05-20-2010 |
| 20100125212 | METHOD AND APPARATUS FOR TESTING ACCURACY OF BLOOD PRESSURE MONITORING APPARATUS - A method for testing accuracy of blood pressure measurement in a blood pressure monitoring apparatus includes calculating a difference between measured blood pressures of a user measured at two or more measurement points, calculating a difference between hydrostatic pressures of blood estimated at the two or more measurement points, and calculating an error of the measured blood pressures. | 05-20-2010 |
| 20100130874 | Apparatus and method for determining a physiologic parameter - An apparatus for determining physiologic parameters of a patient ( | 05-27-2010 |
| 20100137724 | METHOD AND AN APPARATUS FOR DETERMINATION OF BLOOD PRESSURE - The present invention relates to a method and an apparatus for non-interfering blood pressure measurements. In particular, the invention relates to an apparatus for continuously monitoring blood pressure for patients at home or at work. The apparatus comprises an extra-corporal sensor for blood pressure determination with a flexible housing adapted to be attached to the body of a living being proximate to an artery, and an electronic circuit for wireless coupling to a remote transceiver in accordance with the blood pressure in the artery, the remote transceiver adapted for wireless coupling to the sensor for generation of a pressure signal in accordance with the blood pressure in the artery, and a processor connected to the remote transceiver for reception of the pressure signal and adapted to estimate systolic and diastolic pressure based on the signal. | 06-03-2010 |
| 20100152592 | Assessment of Preload Dependence and Fluid Responsiveness - Methods for determining a cardiovascular parameter reflecting fluid or volume changes and for detecting arrhythmia are disclosed. These methods involve receiving a waveform dataset corresponding to an arterial blood pressure, pulseox, Doppler ultrasound or bioimpedance signal and analyzing the waveform to detect irregular cardiac cycles. Irregular cardiac cycles are detected, for example, by comparing parameters of individual cardiac cycles to the parameters of other or average cardiac cycles. If any irregular cardiac cycles are present, their effect is compensated for to form a modified waveform dataset. Once any irregular cardiac cycles are compensated for, a cardiovascular parameter reflecting fluid or volume changes using the modified waveform dataset is calculated. In the method for determining arrhythmia, if the number of irregular cardiac cycles exceeds a predetermined arrhythmia threshold, a user such as a medical professional is notified. | 06-17-2010 |
| 20100160793 | BIOSIGNAL MEASUREMENT MODULES AND METHODS - A biosignal measurement module is provided and includes a biosignal measurement unit, a pose detection unit, and a processing unit. The biosignal measurement unit measures an electrocardiogram signal and a pulse signal of a subject. The pose detection unit detects a position of the biosignal measurement module and outputs position signals. The processing unit receives the electrocardiogram signal, the pulse signal, and the position signals. The processing unit generates a height variation parameter, which indicates the height difference between the position of the biosignal measurement module and a reference position, according to the position signals. The processing unit calculates a current pulse transit time according to the electrocardiogram signal and the pulse signal and compensates for the current pulse transit time according to the height variation parameter to obtain a compensated pulse transit time. The processing unit obtains a blood pressure signal according to the compensated pulse transit time. | 06-24-2010 |
| 20100160794 | BODY-WORN SYSTEM FOR MEASURING CONTINUOUS NON-INVASIVE BLOOD PRESSURE (cNIBP) - The present invention provides a technique for continuous measurement of blood pressure based on pulse transit time and which does not require any external calibration. This technique, referred to herein as the ‘Composite Method’, is carried out with a body-worn monitor that measures blood pressure and other vital signs, and wirelessly transmits them to a remote monitor. A network of body-worn sensors, typically placed on the patient's right arm and chest, connect to the body-worn monitor and measure time-dependent ECG, PPG, accelerometer, and pressure waveforms. The disposable sensors can include a cuff that features an inflatable bladder coupled to a pressure sensor, three or more electrical sensors (e.g. electrodes), three or more accelerometers, a temperature sensor, and an optical sensor (e.g., a light source and photodiode) attached to the patient's thumb. | 06-24-2010 |
| 20100160795 | BODY-WORN SYSTEM FOR MEASURING CONTINUOUS NON-INVASIVE BLOOD PRESSURE (cNIBP) - The present invention provides a technique for continuous measurement of blood pressure based on pulse transit time and which does not require any external calibration. This technique, referred to herein as the ‘Composite Method’, is carried out with a body-worn monitor that measures blood pressure and other vital signs, and wirelessly transmits them to a remote monitor. A network of body-worn sensors, typically placed on the patient's right arm and chest, connect to the body-worn monitor and measure time-dependent ECG, PPG, accelerometer, and pressure waveforms. The disposable sensors can include a cuff that features an inflatable bladder coupled to a pressure sensor, three or more electrical sensors (e.g. electrodes), three or more accelerometers, a temperature sensor, and an optical sensor (e.g., a light source and photodiode) attached to the patient's thumb. | 06-24-2010 |
| 20100160796 | BODY-WORN SYSTEM FOR MEASURING CONTINUOUS NON-INVASIVE BLOOD PRESSURE (cNIBP) - The present invention provides a technique for continuous measurement of blood pressure based on pulse transit time and which does not require any external calibration. This technique, referred to herein as the ‘Composite Method’, is carried out with a body-worn monitor that measures blood pressure and other vital signs, and wirelessly transmits them to a remote monitor. A network of body-worn sensors, typically placed on the patient's right arm and chest, connect to the body-worn monitor and measure time-dependent ECG, PPG, accelerometer, and pressure waveforms. The disposable sensors can include a cuff that features an inflatable bladder coupled to a pressure sensor, three or more electrical sensors (e.g. electrodes), three or more accelerometers, a temperature sensor, and an optical sensor (e.g., a light source and photodiode) attached to the patient's thumb. | 06-24-2010 |
| 20100160797 | BODY-WORN SYSTEM FOR MEASURING CONTINUOUS NON-INVASIVE BLOOD PRESSURE (cNIBP) - The present invention provides a technique for continuous measurement of blood pressure based on pulse transit time and which does not require any external calibration. This technique, referred to herein as the ‘Composite Method’, is carried out with a body-worn monitor that measures blood pressure and other vital signs, and wirelessly transmits them to a remote monitor. A network of body-worn sensors, typically placed on the patient's right arm and chest, connect to the body-worn monitor and measure time-dependent ECG, PPG, accelerometer, and pressure waveforms. The disposable sensors can include a cuff that features an inflatable bladder coupled to a pressure sensor, three or more electrical sensors (e.g. electrodes), three or more accelerometers, a temperature sensor, and an optical sensor (e.g., a light source and photodiode) attached to the patient's thumb. | 06-24-2010 |
| 20100179439 | DEVICE AND METHOD FOR CORRECTING A BLOOD PRESSURE MEASURED - A device for altitude correction of a blood pressure measured at a measuring position of a living being has a transmitter, at least three receivers and an evaluating unit. The transmitter emits a signal from close to a measuring position and the at least three receivers receive the signal, wherein the receivers may be mounted to positions at different altitudes of the living being. The evaluating unit corrects the blood pressure measured on the basis of run time or phase differences of the signals received at the at least three receivers. | 07-15-2010 |
| 20100198085 | Disposable Sensor Device and Monitoring System - The invention relates to a disposable sensor device ( | 08-05-2010 |
| 20100198086 | EXTENDED OPTICAL RANGE SYSTEM FOR MONITORING MOTION OF A MEMBER - A system and method for monitoring a physiological parameter includes a garment that includes a fabric that exhibits both a light transmission property and a light reflection property. The amount of light transmitted through the fabric relative to the amount of light reflected by the fabric changes when the fabric stretches in response to motion, such as the motion induced by physiological activity (e.g., heart rate). The system includes at least one source of radiation having wavelength(s) in the range of 400 to 2200 nanometers and at least one detector responsive to such incident radiation. The source and detector are associated with the fabric such that the reception of incident radiation by the detector is directly affected by a change in the amount of light transmitted through the fabric relative to the amount of light reflected by the fabric when the fabric stretches. A signal processor converts a signal from the detector into a signal representative of at least one predetermined physiological parameter of a wearer of the garment. | 08-05-2010 |
| 20100204588 | METHOD AND APPARATUS FOR DETECTING MEASUREMENT SITE OF BLOOD PRESSURE - An apparatus and method which detects a blood-pressure measurement site. The apparatus for detecting a site of a body to measure blood pressure includes a sensing unit for sensing pressures applied to a blood vessel of a site of the body, a calculation unit for calculating a waveform representing the sensed pressure, and a determination unit for determining whether the site is the optimal site. | 08-12-2010 |
| 20100204589 | NON-INVASIVE INTRACRANIAL PRESSURE SENSOR - A system and method for non-invasively detecting intracranial pressure (ICP) of a living being by detecting impedance mismatches between carotid arteries and cerebral vessels via a reflection of the carotid pressure waveform using a pressure sensor positioned against the palpable carotid artery, as well as analyzing the reflection and comparing the analysis with known cerebral vasculature data, to calculate ICP non-invasively. A remote blood pressure waveform can also be used to compensate for blood system impedance. | 08-12-2010 |
| 20100204590 | Detection of Vascular Conditions Using Arterial Pressure Waveform Data - Multivariate statistical models for the detection of vascular conditions, methods for creating such multivariate statistical models, and methods for the detection of vascular condition in a subject using the multivariate statistical models are described. The models are created based on arterial pressure waveform data from a first group of subjects that were experiencing a particular vascular condition and a second group of subjects that were not experiencing the same vascular condition. The multivariate statistical models are set up to provide different output values for each set of input data. Thus, when data from a subject under observation is input into the model, the relationship of the model output value to the established output values for the two groups upon which the model was established will indicate whether the subject is experiencing the vascular condition. | 08-12-2010 |
| 20100204591 | Calculating Cardiovascular Parameters - Methods for measuring a cardiovascular parameter in a subject regardless of whether the subject is experiencing normal hemodynamic or abnormal hemodynamic conditions are described. These methods involve the determination of whether a subject is experiencing normal hemodynamic conditions or abnormal hemodynamic conditions, then applying an appropriate model to subject data to determine a cardiovascular parameter for the subject. Multivariate Boolean models are used to establish if the subject is experiencing normal hemodynamic or abnormal hemodynamic conditions, then multivariate statistical models are used to calculate the appropriate cardiovascular parameter. Having correct cardiovascular parameters for a subject experiencing abnormal hemodynamic conditions, for example, enables the calculation of accurate values for treatment relevant parameters, such as, cardiac output and stroke volume. | 08-12-2010 |
| 20100204592 | Detection of Parameters in Cardiac Output Related Waveforms - Methods for detecting parameters in cardiac output related waveforms are described. The methods include methods for detecting individual heart beat cycles in a cardiac output related waveform, methods for detecting an error in an assigned starting point for an individual heart beat cycle in a cardiac output related waveform, methods for detecting a dichrotic notch for an individual heart beat cycle in a cardiac output related waveform, and methods for detecting an error in an assigned dichrotic notch for an individual heart beat cycle in a cardiac output related waveform. The identification of these parameters is important for a clinician as these parameters form the basis for the calculation of many other cardiac output related parameters. | 08-12-2010 |
| 20100210954 | SYSTEM AND METHOD FOR DETECTING ARTIFACTUAL HEMODYNAMIC WAVEFORM DATA - A system and method for cardiovascular analysis includes an implantable medical device capable of generating hemodynamic pressure waveform data based upon sensed pressure. Hemodynamic waveform data is analyzed to identify artifactual data represented in the hemodynamic waveform. | 08-19-2010 |
| 20100217134 | METHOD, A SYSTEM AND A COMPUTER PROGRAM PRODUCT FOR DETERMINING A BEAT-TO BEAT STROKE VOLUME AND/OR A CARDIAC OUTPUT - The invention relates to a method | 08-26-2010 |
| 20100217135 | METHOD AND SYSTEM FOR INTERPRETING HEMODYNAMIC DATA INCORPORATING PATIENT POSTURE INFORMATION - Systems and methods for improving hemodynamic data interpretation by accounting for the effects of patient posture is disclosed. In certain embodiments, a posture signal is acquired and used to categorize hemodynamic data according to posture to facilitate distinguishing posture-related changes in acquired hemodynamic data from those due to pathophysiologic changes. Posture information may be used to normalize data acquired in various postures to facilitate interpretation of such data. Baseline measurements of hemodynamic data acquired in various postures may also be used to subsequently detect changes in patient posture without the need for an implanted posture sensor. | 08-26-2010 |
| 20100241011 | Calibration of Pulse Transit Time Measurements to Arterial Blood Pressure using External Arterial Pressure Applied along the Pulse Transit Path - An apparatus and methods for adaptive and autonomous calibration of pulse transit time measurements to obtain arterial blood pressure using arterial pressure variation. The apparatus and methods give pulse transit time (PTT) devices an ability to self-calibrate. The methods apply a distributed model with lumped parameters, and may be implemented, for example, using pulse transit time measurements derived from a wearable photoplethysmograph (PPG) sensor architecture with an intervening pressurizing mechanism. | 09-23-2010 |
| 20100241012 | Portal Vein Pressure Measurement Using Elastography - The shear stiffness of a subject's spleen is measured using elastography techniques such as ultrasound elastography or a magnetic resonance elastography (MRE) acquisition with an MRI system. A relationship between splenic shear stiffness and portal venous blood pressure is modeled and is used to calculate portal venous blood pressure non-invasively from the measured splenic shear stiffness. | 09-23-2010 |
| 20100241013 | Direct Measurements of Arterial Pressure Decoupling - Methods for monitoring central-to-peripheral arterial pressure decoupling, i.e., hyperdynamic or vasodilation conditions are described. These methods involve the comparison of parameters such as impedance, compliance, and pressure that can be determined from flow and pressure measurements at central aortic and peripheral arterial locations. The relationship between the parameters at the central aortic and peripheral arterial locations provides an indication of central-to-peripheral arterial pressure decoupling. These methods can be alert a user that a subject is experiencing central-to-peripheral arterial pressure decoupling, which can enable a clinician to appropriately provide treatment to the subject. | 09-23-2010 |
| 20100249612 | Flow Estimation - Method and apparatus are provided for computing signals related to cardiac output from physiologic input signals related to circulatory pressures or flows. Method and apparatus are provided for constructing a transforming filter and applying said filter to the physiologic input signals in order to obtain a signal proportional to phasic cardiac output or time-averaged cardiac output. This invention provides a means for real-time monitoring of cardiac output and stroke volume which is of great clinical importance but not otherwise feasible by present techniques. | 09-30-2010 |
| 20100249613 | MASSAGE APPARATUS AND MASSAGE PROGRAM - A massage apparatus includes: a massage unit configured to massage a user; a biological information acquisition unit configured to acquire biological information of the user; a stress estimation unit configured to estimate a degree of stress of the user based on the biological information acquired by the biological information acquisition unit; and an operation determination unit configured to determine a massage operation to be performed for the user by the massage unit based on the degree of stress of the user estimated by the stress estimation unit. | 09-30-2010 |
| 20100268096 | Method and Apparatus For Non-Invasive Assessment of Hemodynamic and Functional State of the Brain - A method and apparatus for assessment of hemodynamic and functional state of the brain is disclosed. In one embodiment, the method and apparatus includes non-invasive measurement of intracranial pressure, assessment of the brain's electrical activity, and measurement of cerebral blood flow. In some embodiments, the method and apparatus include measuring the volume change in the intracranial vessels with a near-infrared spectroscopy or other optical method, measuring the volume change in the intracranial vessels with rheoencephalography or other electrical method, and measuring the brain's electrical activity using electroencephalography. | 10-21-2010 |
| 20100268097 | Monitoring Peripheral Decoupling - Methods for monitoring central-to-peripheral arterial pressure decoupling, i.e., hyperdynamic conditions, are described. These methods involve the comparison of parameters calculated from multivariate statistical models established for both subjects experiencing normal hemodynamic conditions and subjects experiencing hyperdynamic conditions, in which central- to peripheral decoupling may occur. The difference or ratio between the parameters calculated using the two multivariate statistical models provides a continual indication of the level of decoupling as well as indicating peripheral decoupling when a threshold value is exceeded. These methods can be used to both alert a user to the fact that a subject is experiencing peripheral decoupling and provide accurate arterial tone measurements, which enable the calculation of accurate values for other parameters, such as stroke volume and cardiac output. | 10-21-2010 |
| 20100274141 | MEASURES OF CARDIAC CONTRACTILITY VARIABILITY DURING ISCHEMIA - Systems and methods include obtaining a measure of cardiac contractility. A cardiac contractility variability is determined from the measure of cardiac contractility. Analyzing the cardiac contractility variability, an indication of cardio-vasculature health is provided. | 10-28-2010 |
| 20100280395 | System and Method for Hypertension Management | 11-04-2010 |
| 20100280396 | System for Cardiac Pathology Detection and Characterization - A system for heart performance characterization and abnormality detection includes an interface for receiving an electrical signal comprising a pressure indicative waveform indicating a heart blood pressure of a patient over a heart beat cycle. A timing detector determines multiple different time periods in at least one heart cycle from the pressure indicative waveform. A patient monitor monitors the multiple different time periods and in response to detection of a variation in at least one of the multiple different time periods exceeding a predetermined threshold or range, generates an alert message associated with the variation. | 11-04-2010 |
| 20100286535 | MEDICAL DEVICE FOR DETECTING PULMONARY ARTERY PRESSURE - In a medical device and method to monitor pulmonary artery pressure of a patient, a first parameter related to the right ventricular straight volume of the patient's is detected, and a second parameter related to the right ventricular ejection rate of the patient's heart, or related to the workload of the patient's heart, is also determined. A pulmonary pressure index is determined by combining the first and second parameters, with variations of the pulmonary pressure index indicating variations in the pulmonary artery pressure. Pulmonary artery hypertension can be monitored with such a device and method. | 11-11-2010 |
| 20100292584 | SPECTRUM ANALYTICAL METHOD FOR QUANTIFYING HEAT-LUNG INTERACTION - The present invention is related to a spectrum analytical method for quantifying hear-lung interaction, which can estimate cardiac function by using a heart-associated monitoring signal. According to the method of the present invention, quantification of heart-lung interaction is conducted by choosing spectrum signals within a specified frequency band, such that the interference to the heart-associated monitoring signals by incidental events occurring at a low frequency, can be avoided. Therefore, the method of the present invention can be performed even in the subjects who are not in a state of general anesthesia or sedation, and hence is very useful in estimating the cardiac function of the test subjects. | 11-18-2010 |
| 20100298719 | METHOD FOR CALCULATING PRESSURES IN A FLUID STREAM THROUGH A TUBE SECTION, ESPECIALLY A BLOOD VESSEL WITH ATHEROSCLEROTIC PLAQUE - A method for calculating pressures in a fluid streaming through a tube section from an upstream end to a downstream end of the tube section, the method comprising scanning the tube section with a scanner and providing a plurality of 2D scanning images along the tube section with an inlet and at least two arms, by a computer program on the basis of the 2D images automatically N calculating a 3D image of the tube section by using interpolating between the 2D images, by a computer program performing a 2D sectional image cut through the 3D image, the image cut following the fluid stream, calculating in the sectional image cut a fluid pressure distribution along multiple locations inside the tube on the basis of given boundary conditions, the boundary conditions including fluid velocity or fluid pressure at the upstream end. | 11-25-2010 |
| 20100298720 | In Situ Energy Harvesting Systems for Implanted Medical Devices - This invention concerns miniature implantable power sources that harvest or scavenge energy from the expansion and contraction of biological tissues, for example, an artery or a bundle of muscle fiber. Such power sources employ an energy harvesting element that converts mechanical or thermal energy existing or generated in or from a pulsatile tissue into a form of electrical energy that can be used or stored by an implanted medical device, such as a blood pressure sensor, a flow meter, or the like. Preferred energy harvesting element embodiments utilize a piezoelectric thin film embedded within a flexible, self-curling medical-grade polymer or coating. Such power sources can be used to produce self-powered implanted microsystems with continuous or near-continuous operation, increased lifetimes, reduced need for surgical replacement, and minimized or eliminated external interface requirements. | 11-25-2010 |
| 20100305457 | METHOD AND APPARATUS FOR ESTIMATING BLOOD PRESSURE - A method for estimating blood pressure includes sensing a sphygmus wave at a body part of a user to which vibration is applied to generate a sensed sphygmus wave, filtering the sensed sphygmus wave to generated a filtered sphygmus wave, and estimating blood pressure of the user based on time differences between peaks of the sensed sphygmus wave and peaks of the filtered sphygmus wave. | 12-02-2010 |
| 20100312125 | System for Cardiac Pathology Detection and Characterization - A system for heart performance characterization and abnormality detection includes an interface for receiving digitized electrical signals representing blood pressure waveforms over one or more heart beat cycles. The digitized electrical signals comprise, a first digital data sequence representing normal blood pressure of a patient, a second digital data sequence representing random blood pressure of a normal patient and a third digital data sequence representing a potentially abnormal blood pressure of a patient. A complexity processor calculates first, second and third complexity indices for the corresponding first, second and third digital data sequences respectively. A correlation processor uses the calculated first, second and third complexity indices to calculate one or more measures indicating deviation of the potentially abnormal blood pressure of the patient from a normal value. | 12-09-2010 |
| 20100317976 | DEVICE AND PROCESS FOR CALCULATING NEW INDICES OF ARTERIAL STIFFNESS, AND/OR FOR STROKE VOLUME MONITORING - A process for calculating an indice of arterial stiffness, including the step of extracting pulse wave analysis data from a recorded pressure of an artery, the recorded pressure is recorded as a function of time, the indice being calculated as a function of the extracted data, and the extracted pulse wave analysis data including at least one time interval. | 12-16-2010 |
| 20110009754 | ARTERIAL BLOOD PRESSURE MONITORING DEVICES, SYSTEMS AND METHODS USING CARDIOGENIC IMPEDANCE SIGNAL - Provided herein are implantable systems, and methods for use therewith, for monitoring a patient's arterial blood pressure. Electrode(s) implanting within and/or on the patient's heart are used to obtain a cardiogenic impedance (CI) signal indicative of cardiac contractile activity. Additionally, a signal (e.g., PPG or IPG signal) indicative of changes in arterial blood volume remote from the patient's heart is obtained using a sensor or electrodes that are implanted remote from the patient's heart. One or more metrics indicative of pulse arrival time (PAT) are determined, where each metric can be determined by determining a time from one of the detected features of the CI signal to one of the detected features of the signal indicative of changes in arterial blood volume. Based on at least one of the metric(s) indicative of PAT, arterial blood pressure is estimated, which can include determining values indicative of systolic blood pressure, diastolic blood pressure, pulse pressure and/or mean arterial blood pressure, and/or changes in such values. | 01-13-2011 |
| 20110009755 | ARTERIAL BLOOD PRESSURE MONITORING DEVICES, SYSTEMS AND METHODS FOR USE WHILE PACING - Provided herein are implantable systems, and methods for use therewith, for monitoring a patient's arterial blood pressure while a patient's heart is being paced. A signal (e.g., PPG or IPG signal) indicative of changes in arterial blood volume remote from the patient's heart is obtained using a sensor or electrodes that are implanted remote from the patient's heart. One or more metrics indicative of pulse arrival time (PAT) are determined, where each metric can be determined by determining a time from a paced cardiac event to one or more predetermined features of the signal indicative of changes in arterial blood volume. Based on at the metric(s) indicative of PAT, arterial blood pressure is estimated, which can include determining values indicative of systolic blood pressure, diastolic blood pressure, pulse pressure and/or mean arterial blood pressure, and/or changes in such values. | 01-13-2011 |
| 20110021929 | SYSTEMS AND METHODS FOR CONTINUOUS NON-INVASIVE BLOOD PRESSURE MONITORING - Systems and methods are disclosed herein for continuous non-invasive blood pressure (CNIBP) monitoring. Multiple reference blood pressure values may be obtained using a calibration device. These multiple reference blood pressure values may be used as calibration points for determining a relationship between the blood pressure of a patient and photoplethysmograph (PPG) signals. | 01-27-2011 |
| 20110021930 | SUPPORT DEVICE FOR SENSORS AND/OR ACTUATORS THAT CAN BE PART OF A WIRELESS NETWORK OF SENSORS/ACTUATORS - A support device for sensors and/or actuators, of a node element or End Device ( | 01-27-2011 |
| 20110034812 | PULMONARY ARTERY PRESSURE BASED SYSTOLIC TIMING INTERVALS AS A MEASURE OF RIGHT VENTRICULAR SYSTOLIC PERFORMANCE - Systems and methods include identifying a first portion and a second portion of a pulmonary artery pressure (PAP) signal during a cardiac cycle. A first timing interval between the first portion and the second portion is obtained and data related to the first timing interval is trended to provide a chronic physiological prognostic indicator. In an embodiment, a second timing interval is obtained from a third portion and a fourth portion of the PAP signal. Then, a function of the first and second timing intervals is trended to provide the chronic physiological prognostic indicator. In one instance, a ratio of the first interval to the second interval is calculated to provide an estimated right ventricle ejection fraction (RVEF) and the RVEF is trended. | 02-10-2011 |
| 20110034813 | METHODS AND APPARATUS FOR DETERMINING CARDIAC OUTPUT - The present invention provides methods and apparatus for determining a dynamical property of the systemic or pulmonary arterial tree using long time scale information, i.e., information obtained from measurements over time scales greater than a single cardiac cycle. In one aspect, the invention provides a method and apparatus for monitoring cardiac output (CO) from a single blood pressure signal measurement obtained at any site in the systemic or pulmonary arterial tree or from any related measurement including, for example, fingertip photoplethysmography. | 02-10-2011 |
| 20110034814 | METHOD AND DEVICE FOR MONITORING A VASCULAR ACCESS AND EXTRACORPOREAL BLOOD TREATMENT DEVICE COMPRISING A DEVICE FOR MONITORING VASCULAR ACCESS - The invention relates to a method and a device for monitoring a vascular access during an extracorporeal blood treatment. The method and the device according to the invention are based on the monitoring of the difference between the venous pressure measured by a venous pressure sensor and the arterial pressure measured by an arterial pressure sensor (in the extracorporeal blood circuit. According to the method and the device according to the invention, a test function describing disturbances in the extracorporeal blood circuit is determined. Said test function is used to determine a noise-free differential pressure from the measured venous and arterial pressure, said differential pressure being evaluated in an arithmetic and evaluation unit to identify a defective vascular access. | 02-10-2011 |
| 20110040194 | METHOD AND SYSTEM FOR DETERMINING CARDIAC PARAMETERS - The present invention explains a method and system for providing all the relevant cardiac parameters in real time and in a fast manner, which are required for the cardiac analysis. The invention involves determining a first area and a second area, the first area under a waveform representing an aortic pressure, and extends between an onset of the systole and the end of the systole and the second area extends between a waveform representing a left ventricle pressure and a waveform adapted to represent the left atrium pressure of the same systole. The method further involves presenting a functional relationship between the first area and the second area on the one hand side and the cardiac parameters on the other hand side and then finally determining the cardiac parameters based on the first area and the second area by using the representation of the functional relationship. | 02-17-2011 |
| 20110040195 | METHOD AND APPARATUS TO DETERMINE THE END OF THE SYSTOLIC PART OF A PRESSURE CURVE - The invention relates to a method and an apparatus for determining the systolic phase interval (SP) of an arterial pressure curve with a starting point (t | 02-17-2011 |
| 20110046492 | MONITORING FOR MITRAL VALVE REGURGITATION - Implantable systems, and methods for use therein, for monitoring for mitral valve regurgitation (MR) are provided. An electrogram (EGM) signal and a corresponding pressure signal are obtained, where the EGM signal is representative of electrical functioning of the patient's heart during a plurality of cardiac cycles, and the corresponding pressure signal is representative of pressure within the left atrium the patient's heart during the cardiac cycles. Windows of the pressure signal are defined, based on events detected in the EGM signal, and measurements from the windows are used to monitor for MR. | 02-24-2011 |
| 20110046493 | SYSTEM AND METHOD FOR GENERATING BASELINE DATA FOR AUTOMATED MANAGEMENT OF CARDIOVASCULAR PRESSURE - A system and method for generating baseline data for automated management of cardiovascular pressure is disclosed. Collected device measures are accumulated to record raw physiometry for a patient, wherein the patient is regularly monitored by an implantable medical device, beginning with an initial observation period. Derived device measures are generated to provide derivative physiometry determined at least in part from the collected device measures. A patient status indicator is determined by analyzing the collected and derived device measures to diagnose a pathophysiology indicative of an absence, onset, progression, regression, and status quo in cardiovascular pressure, wherein the collected and derived device measures and the patient status indicator originating from the initial observation period include baseline data. | 02-24-2011 |
| 20110054328 | BIOLOGICAL INFORMATION MONITOR - A biological information monitor includes: a first measuring unit which measures a pulse wave propagation time of a patient; a second measuring unit which measures a blood pressure of the patient; a calculating unit which calculates an estimated blood pressure value of the patient based on the pulse wave propagation time of the patient; a setting unit which sets a threshold; and a determining unit which compares the estimated blood pressure value with the threshold. The second measuring unit is activated to measure the blood pressure of the patient at least one of at time intervals and at a time when an operator operates the second measuring unit, and the second measuring unit is activated to measure the blood pressure of the patient by the determining unit based on the comparison result. | 03-03-2011 |
| 20110066043 | SYSTEM FOR MEASURING VITAL SIGNS DURING HEMODIALYSIS - The invention provides a system for continuously monitoring a patient during hemodialysis. The system includes a hemodialysis machine for performing the hemodialysis process that features a controller, a pump, a dialyzer filter, a lumen, and an interface to a body-worn monitor. A patient attaches to the dialysis machine through the lumen, and wears a body-worn monitor for continuously measuring blood pressure. The monitor includes an optical system for measuring an optical waveform, an electrical system for measuring an electrical waveform, and a processing component for determining a transit time between the optical and electrical waveforms and then calculating a blood pressure value from the transit time. The body-worn monitor features an interface (e.g. a wired serial interface, or a wireless interface) to transmit the blood pressure value to the controller within the hemodialysis machine. The controller is configured to receive the blood pressure value, analyze it, and in response adjust the dialysis process. | 03-17-2011 |
| 20110066044 | BODY-WORN VITAL SIGN MONITOR - The invention provides a body-worn monitor featuring a processing system that receives a digital data stream from an ECG system. A cable houses the ECG system at one terminal end, and plugs into the processing system, which is worn on the patient's wrist like a conventional wristwatch. The ECG system features: i) a connecting portion connected to multiple electrodes worn by the patient; ii) a differential amplifier that receives electrical signals from each electrode and process them to generate an analog ECG waveform; iii) an analog-to-digital converter that converts the analog ECG waveform into a digital ECG waveform; and iv) a transceiver that transmits a digital data stream representing the digital ECG waveform (or information calculated from the waveform) through the cable and to the processing system. Different ECG systems, typically featuring three, five, or twelve electrodes, can be interchanged with one another. | 03-17-2011 |
| 20110066045 | BODY-WORN VITAL SIGN MONITOR - The invention provides a body-worn monitor featuring a processing system that receives a digital data stream from an ECG system. A cable houses the ECG system at one terminal end, and plugs into the processing system, which is worn on the patient's wrist like a conventional wristwatch. The ECG system features: i) a connecting portion connected to multiple electrodes worn by the patient; ii) a differential amplifier that receives electrical signals from each electrode and process them to generate an analog ECG waveform; iii) an analog-to-digital converter that converts the analog ECG waveform into a digital ECG waveform; and iv) a transceiver that transmits a digital data stream representing the digital ECG waveform (or information calculated from the waveform) through the cable and to the processing system. Different ECG systems, typically featuring three, five, or twelve electrodes, can be interchanged with one another. | 03-17-2011 |
| 20110071407 | DEVICE FOR ACQUIRING PHYSIOLOGICAL VARIABLES MEASURED IN A BODY - The present invention relates to an eavesdropping device for monitoring measured physiological variables of an individual, which eavesdropping device comprises a receiver and a communication interface. The eavesdropping device of the present invention is typically applied in a system comprising a first sensor arranged to be disposed in or outside the body of the individual for measuring aortic blood pressure P | 03-24-2011 |
| 20110077531 | SYSTEMS AND METHODS FOR HIGH-PASS FILTERING A PHOTOPLETHYSMOGRAPH SIGNAL - According to embodiments, systems and methods for high-pass filtering a plethysmograph or photoplethysmograph (PPG) signal are disclosed. A sensor or probe may be used to obtain a plethysmograph or PPG signal from a subject. The sensor may be placed at any suitable location on the body, e.g., the forehead, finger, or toe. The PPG signal generated by the sensor may be high-pass filtered to disambiguate certain features of the PPG signal, including one or more characteristic points. The cut-off frequency for the high-pass filter may be greater than 0.75 Hz and less than 15 Hz. The cut-off frequency for the high-pass filter may be selected to be greater than the subject's computed pulse rate. These characteristic points on the filtered PPG signal may be used to compute non-invasive blood pressure measurements continuously or on a periodic basis. For example, the time difference between two or more characteristic points in a high-pass filtered version of the generated PPG signal may be computed. The time difference may be used to compute non-invasive blood pressure measurements continuously or on a periodic basis. | 03-31-2011 |
| 20110077532 | Method and Apparatus for Assessment of Fluid Responsiveness - Methods and apparatus for determining a cardiac parameter from cardiovascular pressure signals including arterial blood pressure (ABP) and the photoplethysmographic signal to quantify the degree of amplitude modulation due to respiration and predict fluid responsiveness are disclosed. Disclosed embodiments include a method for assessing fluid responsiveness implemented in a digital computer with one or more processors comprising: (a) measuring a cardiovascular signal, and (b) computing a dynamic index predictive of fluid responsiveness from said cardiovascular signal using a nonlinear state space estimator. According to one particular embodiment, and without limitation, the nonlinear state space estimator is based on a model for cardiovascular signals such as arterial blood pressure or plethysmogram signals, and employs a marginalized particle filter to estimate a dynamic index predictive of fluid responsiveness that is substantially equivalent to a variation in pulse pressure of said cardiovascular signal. | 03-31-2011 |
| 20110077533 | APPARATUS FOR ASSESSING RISK OF CEREBROVASCULAR DISEASES - The apparatus for assessing the risk of cerebrovascular diseases comprises a sensor part | 03-31-2011 |
| 20110087116 | SYSTEM, METHODS AND DEVICES FOR MAINTENANCE, GUIDANCE AND/OR CONTROL - Methods, systems, devices and computer program products for providing maintenance, guidance and/or control of certain systems are disclosed. Typically, in some aspects the systems are complex. Also disclosed are methods, systems, devices and computer program products for providing therapeutic guidance for controlling a subject's circulation. One such method comprises the steps of: (i) determining the subject's present and desired circulatory states as a function of at least mean systemic filling pressure (Pms), heart efficiency (EH) and systemic vascular resistance (SVR); (ii) determining a target direction of a trajectory from the subject's present circulatory state to said subject's desired circulatory state, wherein treatment of the subject so as to traverse the trajectory will cause the subject's circulatory state to move towards a desired circulatory state; and (iii) visually representing the target direction of the trajectory. | 04-14-2011 |
| 20110092827 | BLOOD PRESSURE MONITOR AND METHOD FOR CALCULATING BLOOD PRESSURE THEREOF - A blood pressure monitor and a method for calculating blood pressure thereof are revealed. The blood pressure monitor includes a cuff, an air pump, an air escape valve, a pressure sensor, a processing circuit, and an arithmetic circuit. The cuff is arranged a a body to be detected while and the air pump inflates the cuff and the air escape valve is for releasing air from the cuff. The pressure sensor is disposed on the cuff for detecting cuff pressure to generate analog pressures sensing signals. The processing circuit processes the analog pressure sensing signals and generates digital pressure sensing signals. A slope of each digital pressure sensing signal is calculated by the arithmetic circuit. A pressure value of the digital pressure sensing signal corresponding to a maximum slope is an average blood pressure. Then find a second derivative of each digital pressure sensing signal. A pressure value of the digital pressure sensing signal corresponding to a largest maximum value of the second derivative is systolic pressure while a pressure value of the digital pressure sensing signal corresponding to a smallest minimum value of the second derivative is diastolic pressure. | 04-21-2011 |
| 20110092828 | Fluid Delivery System, Fluid Path Set, and Pressure Isolation Mechanism with Hemodynamic Pressure Dampening Correction - The fluid delivery system includes a pressurizing device for delivering injection fluid under pressure, a low pressure fluid delivery system, and a pressure isolation mechanism. The pressure isolation mechanism includes a first lumen associated with the pressurizing device, a second lumen associated with the low pressure fluid delivery system, and a pressure isolation port. The first valve is in a normally open position permitting fluid communication between the first lumen and the second lumen and movable to a closed position when fluid pressure in the first lumen reaches a predetermined pressure level. The first valve isolates the pressure isolation port from the first lumen in the closed position. A second valve is associated with the second lumen and regulates fluid flow through the second lumen. The second valve may be a disk valve defining one or more passageways in the form of slits through the body of the disk valve. | 04-21-2011 |
| 20110098579 | BLOOD-PRESSURE SENSOR SYSTEM - There is provided a blood-pressure sensor system wherein a blood-pressure sensor including a plurality of structures which induces surface plasmon resonance on a light-receiving plane of a photoelectric conversion element is attached to an outer wall of a blood vessel, in which if the blood-pressure sensor is deformed according to expansion or contraction of the blood vessel, an interval of layout of the structure is changed (widened or narrowed), so that an incident form of light with respect to the structures is changed to cause the output from the photoelectric conversion element to be changed. The output is measured as an open circuit voltage, and index calculation is performed, so that a blood pressure value is measured. | 04-28-2011 |
| 20110098580 | Method and System for Treating Hypotension - A system and method for treating hypotension in a mammal including a measuring device for measuring the blood pressure in a blood vessel having a wireless transmitter therein for emitting a signal when the measured blood pressure moves into a predetermined range. The system also includes an injection device fixed on the skin of a mammal, the injection device having a receiver for receiving the signal emitted from the wireless transmitter, a drug reservoir, a conduit for moving drug from the drug reservoir through the skin upon activation, and an activation device that causes the drug to move from the drug reservoir through the conduit and into the mammal upon receiving the signal emitted from the wireless transmitter. | 04-28-2011 |
| 20110105916 | Diagnostic method and apparatus - An electrical interferential device comprises a circuit for delivering electrical interferential energy into the body of a patient. A sensor detects a function of the autonomic nervous system of the patient and provides an output indicative of the response of the autonomic nervous system to the electrical interferential energy. A treatment regimen is selected which uses a combination of carrier and beat frequencies and electrode placement pattern that produce a desired response in the autonomic nervous system of the patient. In one embodiment of the invention, a diagnostic tool is used to determine which combination of carrier and beat frequencies are desirable and treatment is provided by a second electrical interferential device. In another embodiment of the invention, the same diagnostic tool or a portion of the same diagnostic tool may be used to treat the patient. | 05-05-2011 |
| 20110125033 | BLOOD PRESSURE ESTIMATION APPARATUS AND BLOOD PRESSURE ESTIMATION METHOD - [Problem to be Solved] To provide a non-invasive blood pressure estimation apparatus which can accurately estimate systolic blood pressure from blood flow sound of a dialysis patient and can continuously estimate systolic blood pressure by continuously picking up the blood flow sound of the subject. | 05-26-2011 |
| 20110125034 | VESSEL WALL MONITORING APPARATUS - A vessel wall monitoring apparatus includes: a first detecting unit which detects vessel diameter information based on first biological information obtained from a subject; a first producing unit which differentiates the vessel diameter information detected by the first detecting unit, to produce a vessel diameter function; a second detecting unit which detects blood pressure based on second biological information obtained from the subject; a second producing unit which performs a logarithmic operation on the blood pressure detected by the second detecting unit, to produce a logarithmic blood pressure function; and an outputting unit which produces an impedance model expression by using the vessel diameter function, the logarithmic blood pressure function, and mechanical characteristic values including a stiffness, viscosity, and inertia, and which calculates and outputs at least one of the stiffness, the viscosity, and the inertia based on the impedance model expression. | 05-26-2011 |
| 20110137182 | METHODS AND DEVICES FOR ASSESSING INTRACRANIAL PRESSURE - Provided are methods for noninvasively assessing intracranial pressure (“ICP”) based on optic nerve sheath diameter (“ONSD”) and a blood velocity metric, such as pulsatility or resistivity index. Also provided are related devices and systems for performing the claimed methods. | 06-09-2011 |
| 20110137183 | EVALUATE AORTIC BLOOD PRESSURE WAVEFORM USING AN ADAPTIVE PERIPHERAL PRESSURE TRANSFER FUNCTION - The invention relates to method for reconstructing an aortic blood pressure waveform of a person from a peripheral blood pressure waveform of the person comprising the steps of determining at least one pre-selected parameter of the peripheral blood pressure waveform, reconstructing the aortic blood pressure waveform from the peripheral blood pressure waveform using a pressure transfer function having at least one adjustable characteristics, wherein said adjustable characteristics is determined using the at least one pre-selected parameter of the peripheral blood pressure waveform. The invention further relates to a device for reconstructing an aortic blood pressure waveform from a peripheral blood pressure waveform and a computer program product. | 06-09-2011 |
| 20110137184 | PRESSURE SENSING - A high electron mobility transistor (HEMT) is disclosed capable of performing as a pressure sensor. In one embodiment, the subject pressure sensor can be used for the detection of body fluid pressure. A piezoelectric, biocompatible film can be used to provide a pressure sensing functionalized gate surface for the HEMT. Embodiments of the disclosed sensor can be integrated with a wireless transmitter for constant pressure monitoring. | 06-09-2011 |
| 20110152697 | Circulatory Pressure Monitoring Using Infusion Pump Systems - A low cost, transportable system for monitoring the central venous pressure of a patient receiving an infusion is provided. The pressure monitoring system of the present invention employs a pump and a flow meter in order to supply infusion fluids to a patient. Based upon the control factors and changes thereof communicated to the pump by a controller in order to achieve and maintain a desired infusion fluid flow rate, relative changes in patient's venous pressure and/or quantitative pressure data is obtained. | 06-23-2011 |
| 20110166458 | METHOD AND APPARATUS FOR NON-INVASIVELY MEASURING HEMODYNAMIC PARAMETERS USING PARAMETRICS - An improved method and apparatus for non-invasively assessing one or more hemodynamic parameters associated with the circulatory system of a living organism. In one aspect, the invention comprises a method of measuring a hemodynamic parameter (e.g., arterial blood pressure) by applanating or compressing portions of tissue proximate to the blood vessel of concern until a desired condition is achieved, and then measuring the hemodynamic parameter. Such applanation effectively mitigates transfer and other losses created by the tissue proximate to the blood vessel, thereby facilitating accurate and robust tonometric measurement. An algorithm adapted to maintain optimal levels of applanation is also described. Methods and apparatus for scaling such hemodynamic parameter measurements based on subject physiology, and providing treatment to the subject based on the measured parameters, are also disclosed. | 07-07-2011 |
| 20110166459 | PIEZOELECTRIC SENSOR FOR MEASURING PRESSURE FLUCTUATIONS - The invention relates to a piezoelectric sensor for the improved measurement of mechanical variables such as force, pressure or measurement variables which are derived there from, particularly a PVDF film sensor having an improved sensitivity and temperature stability of the measurement signal for pressure measurements that vary in time and/or space, and for the one- and two-dimensional determination of the position and propagation velocity of pressure fluctuations and pressure waves with a single measurement sensor at a measurement location. A preferred field of application of the invention is the non-invasive, low strain and continuous measurement of the pulse rate and the systolic and diastolic blood pressure of humans and animals by determining the velocity and the signal form of the pulse waves. The object of the invention is to allow the measurements of the blood pressure and the pulse rate, for example even in the case of emergency patients having only a very low blood pressure and patients having circulatory disorders in the extremities, for example patients which have developed diabetes or the “smoker's leg”, by using only one sensor at a measurement location due to the improved measurement sensitivity of the piezoelectric sensor, with the result that the continuous application of a pressurized jacket for continuously measuring and monitoring the blood pressure is not necessary. The present invention solves this problem in that a plurality of parallel strips of a piezoelectric material ( | 07-07-2011 |
| 20110172545 | Active Physical Perturbations to Enhance Intelligent Medical Monitoring - Tools and techniques for enhancing intelligent medical monitoring, and in particular monitoring that employs models for estimating and/or predicting physiological conditions. In an aspect, some of these tools and techniques employ active physical perturbation of a test subject (or patient), to induce physiological changes in the subject. By monitoring one or more of the patient's physiological parameters shortly before, during, and/or after the physical perturbation, the subject's reaction to the perturbation can be determined, and this reaction can be used to estimate and/or predict the subject's physiological state and/or clinical condition. In a particular case, the subject's response to the physical perturbation can be used to construct and/or refine a model that can be applied to analyze the subject's physiological parameters to produce such predications and/or estimations. | 07-14-2011 |
| 20110172546 | ARTERIAL-WALL STIFFNESS EVALUATION SYSTEM - An arterial-wall stiffness evaluation system of the present invention includes: a cuff to be attached to a part of a living body; a pressure sensor for detecting pressure in the cuff; a cuff-pressure control section for controlling the pressure in the cuff to be increased or decreased up to a predetermined value, based on a value detected by the pressure sensor; and a data processing section for calculating, based on pulse waves detected by the pressure sensor, pulse-wave amplitudes of cuff-pressure pulse waves and blood-pressure pulse waves, and for evaluating arterial-wall stiffness based on the pulse-wave amplitudes. The arterial-wall stiffness is evaluated by a pressure-diameter characteristic curve, which represents a relationship between vascular diameter and transmural pressure applied to a vascular wall, or by estimation from shapes and amplitudes of the detected pulse waves. Alternatively, the evaluation is performed by estimating, from the detected pulse waves, a differential function obtainable by differentiating a pressure-diameter characteristic curve with respect to a transmural pressure, or by use of an arctan or a sigmoid function. This allows anybody to easily evaluate blood vessel stiffness anytime with high accuracy even at home without any special knowledge. | 07-14-2011 |
| 20110178415 | CONTINUOUS, NON-INVASIVE, OPTICAL BLOOD PRESSURE MONITORING SYSTEM - The invention comprises a system of wearable devices that collectively allow for the continuous, non-invasive, measurement and monitoring of blood pressure, without the use of an inflatable cuff. The system incorporates: 1) An optical module, which is comprised of a coherent source of light, a semi-transparent hologram, microscope optics for viewing the interference pattern developed between the illuminated hologram and arterial blood, a spatial light modulator (SLM), and processing electronics with Bluetooth capability that facilitates digitization and wireless transmission of the fringe pattern to, 2) a personal digital assistant (PDA) that is worn on a waist belt. The PDA and associated software allow for continuous calculation and monitoring of real-time arterial blood pressure from the digitized fringe patterns received. The system further comprises 3) a personal computer (PC) with wireless capacity and connection to the internet. Continuous BP function, alerts, condition and medical assessment is conducted through PDA-PC communications with internet based medical facility. | 07-21-2011 |
| 20110196244 | SYSTEM AND APPARATUS FOR THE NON-INVASIVE MEASUREMENT OF BLOOD PRESSURE - The present invention relates to a system for the estimation of the systolic (SBP), diastolic (DBP) and average (MAP) blood pressure. Said system establishes a physiological model of the pulse wave combined with its energy for, afterwards, generating a fixed length vector containing the previous model's values with other variables related to the user like, for example, age, sex, height, weight, etc. . . . This fixed length vector is used as an input of a function estimator system based on “random forests” for the calculation of the three variables of interest. The main advantage of this function estimator lies in that it does not impose any restriction beforehand over the function to be estimated, and it is also very reliable with heterogeneous data, as in the present invention's case. | 08-11-2011 |
| 20110201947 | OXIDIZED PARAOXONASE 1 AND PARAOXONASE 1/HDL PARTICLE NUMBER RATIO AS RISK MARKERS FOR CARDIOVASCULAR DISEASE - The present invention provides methods and markers for characterizing a subject's, particularly a human subject risk of having cardiovascular disease. The present invention also provides methods of characterizing a subject's risk of developing cardiovascular disease. In another embodiment, the present invention provides methods for characterizing a subject's risk of experiencing a complication of cardiovascular disease or major adverse cardiac event within 1, 3, or 10 years. In another embodiment, the present invention provides a method for determining whether a subject presenting with chest pain is at risk near term of experiencing a heart attack or other major adverse cardiac event. The present methods are especially useful for identifying those subjects who are in need of highly aggressive CVD therapies as well as those subjects who require no therapies targeted at inhibiting or preventing CVD or complications of CVD. | 08-18-2011 |
| 20110208066 | NONINVASIVE BLOOD PRESSURE MEASUREMENT AND MONITORING DEVICE - Measurement of blood pressure is one of the most common procedures done in a clinical and an ambulatory environment. It is usually done with a sphygmomanometer, where an inflatable cuff is attached to the arm of a patient and the systolic and diastolic pressures are determined, typically by listening to the Korotkoff sounds. Although this method is over 100 years old and widely used, it is well known that it has severe shortcomings. | 08-25-2011 |
| 20110213254 | METHOD OF DETERMINING BLOOD PRESSURE AND AN APPARATUS FOR DETERMINING BLOOD PRESSURE - An apparatus and method enables a reading of a continuous beat to beat heart rate at the superficial temporal artery to give an indication of blood pressure of the brain and blood related diseases. The apparatus is non-invasive. Preferably a reading of a continuous beat to beat heart rate is measured on both the left superficial temporal artery and the right superficial temporal artery simultaneously during the same heart beat. Where the wave form measured from the left temporal artery differs from the wave form measured from the right temporal artery this may be an indication of an impending stroke or an indication that a stroke has recently happened. Further, the indices of the wave forms may be used as a clinical indication of other blood related diseases. | 09-01-2011 |
| 20110224556 | BODY-WORN VITAL SIGN MONITOR - The invention provides a body-worn vital sign monitor that measures a patient's vital signs (e.g. blood pressure, SpO2, heart rate, respiratory rate, and temperature) while simultaneously characterizing their activity state (e.g. resting, walking, convulsing, falling) and posture (upright, supine). The monitor processes this information to minimize corruption of the vital signs and associated alarms/alerts by motion-related artifacts. It also features a graphical user interface (GUI) rendered on a touchpanel display that facilitates a number of features to simplify and improve patient monitoring and safety in both the hospital and home. | 09-15-2011 |
| 20110224557 | BODY-WORN VITAL SIGN MONITOR - The invention provides a body-worn vital sign monitor that measures a patient's vital signs (e.g. blood pressure, SpO2, heart rate, respiratory rate, and temperature) while simultaneously characterizing their activity state (e.g. resting, walking, convulsing, falling) and posture (upright, supine). The monitor processes this information to minimize corruption of the vital signs and associated alarms/alerts by motion-related artifacts. It also features a graphical user interface (GUI) rendered on a touchpanel display that facilitates a number of features to simplify and improve patient monitoring and safety in both the hospital and home. | 09-15-2011 |
| 20110230771 | HEART FAILURE STATUS MONITORING - Left atrial pressure and temperature of a patient are monitored to identify a normal wake state, a normal sleep state, and any deviation from those normal states (e.g., an alarm state). In the event an alarm state is identified, a determination is made as to whether to generate an indication of heart failure exacerbation based on a heart failure score. In addition, congestion and perfusion in a patient may be monitored over time to provide a two-dimensional indication of a trend relating to the heart failure status of the patient. | 09-22-2011 |
| 20110230772 | METHOD AND DEVICE FOR INVASIVE BLOOD PRESSURE MEASUREMENT IN A VASCULAR ACCESS - A device and method for invasive blood pressure measurement in a vascular access under continuous blood flows in a treatment device in extracorporeal detoxification methods is provided. Systemic arterial pressure is directly measured using an existing vascular access for dialysis, or in which the systemic arterial pressure and the temporal progression of such pressure are determined indirectly. A valve-controlled bypass system which goes around a blood pumping unit is provided so that the blood flow in the treatment device is not interrupted, and alarms are suppressed The bypass module is easily connectable to measuring equipment on various treatment units without having to adjust the same. | 09-22-2011 |
| 20110230773 | METHOD OF DERIVING CENTRAL AORTIC SYSTOLIC PRESSURE VALUES AND METHOD FOR ANALYSING AN ARTERIAL DATASET TO DERIVE THE SAME - A method, system and computer readable medium for deriving central aortic systolic pressure by reversing the order of a set of predetermined number of blood pressure measurements to obtain a reversed blood pressure set; averaging the reversed blood pressure set such that the average set represents a moving average waveform; overlaying the reversed blood pressure set and the moving average waveform; identifying a point of intersection on the reversed arterial waveform and the moving average waveform, and setting the central aortic systolic pressure as a reversed blood pressure value in the reversed blood pressure set nearest to the point of intersection. | 09-22-2011 |
| 20110237960 | METHOD, SYSTEM AND APPARATUS FOR MONITORING PATIENTS - A method, system and apparatus are disclosed for monitoring a subject with a transport monitor comprising a measurement unit including at least one magnetic component unit operative when monitoring the subject in absence of a high magnetic field. To maintain the monitoring capacity of a standard transport monitor even in the high magnetic field, the transport monitor is provided with a reconfiguration unit adapted to reconfigure the measurement unit for the high magnetic field so that at least part of the monitoring capability that the measurement unit has in absence of the high magnetic field is preserved in presence of the high magnetic field. | 09-29-2011 |
| 20110237961 | METHODS AND APPARATUS FOR CONTROL OF NON-INVASIVE PARAMETER MEASUREMENTS - Improved methods and apparatus for non-invasively assessing one or more parameters associated with fluidic systems such as the circulatory system of a living organism. In a first aspect, an improved method of continuously measuring pressure from a compressible vessel is disclosed, wherein a substantially optimal level of compression for the vessel is achieved and maintained using perturbations (e.g., modulation) of the compression level of the vessel. In one exemplary embodiment, the modulation is conducted according to a pseudo-random binary sequence (PBRS). In a second aspect, an improved apparatus for determining the blood pressure of a living subject is disclosed, the apparatus generally comprising a pressure sensor and associated processor with a computer program defining a plurality of operating states related to the sensed pressure data. Methods for pressure waveform correction and reacquisition, as well as treatment using the present invention, are also disclosed. | 09-29-2011 |
| 20110245690 | SYSTEMS AND METHODS FOR MEASURING ELECTROMECHANICAL DELAY OF THE HEART - Systems and methods are disclosed herein for measuring the electromechanical delay of the heart of a patient. An electrocardiogram (EKG) signal may be used to detect heart electrical activity. Photoplethysmograph (PPG) signals may be used to detect heart mechanical activity. The electromechanical delay may be calculated based at least in part on the timing of an EKG signal and at least two PPG signals. | 10-06-2011 |
| 20110245691 | NON-INVASIVE METHODS AND SYSTEMS FOR ASSESSING CARDIAC FILING PRESSURE - Featured are methods and systems for assessing cardiac filing pressure non-invasively. Such methods include, inter alia, arranging a photoplethysmography (PPG) transducer on a finger of a patient and fluidly coupling a pressure transducer to the patient's mouth so that the pressure transducer measures expiratory pressure. The PPG transducer provides an output of a pulse volume signal of cardiac circulatory flow. Such methods also including determining a pulse amplitude ratio, using the pulse volume near the end of the expiratory effort and a baseline pulse volume, and assessing the pulse amplitude ratio so as to determine a filing pressure condition for the heart of the patient. | 10-06-2011 |
| 20110245692 | METHOD AND SYSTEM FOR IMPROVING PHYSIOLOGIC STATUS AND HEALTH VIA ASSESSMENT OF THE DYNAMIC RESPIRATORY ARTERIAL PRESSURE WAVE USING PLETHYSMOGRAPHIC TECHNIQUE - The present invention specifies a method and system for assessing the dynamic respiratory arterial pressure wave using plethysmographic sensing techniques. The dynamic respiratory arterial pressure wave is measured and plotted for purposes of diagnosis and or remedial biofeedback. | 10-06-2011 |
| 20110257537 | BLOOD PRESSURE MONITORING SYSTEM PROVIDING ENHANCED VASCULAR ANEURYSM DETECTION FEATURES AND RELATED METHODS - A blood pressure monitoring system may include a plurality of a blood pressure measuring devices each configured to measure blood pressure of a respective extremity of a patient, and a blood pressure monitoring device. The blood pressure monitoring device may include at least one interface device configured to interface with the plurality of blood pressure measuring devices, and a controller coupled to the at least one interface device. The controller may be configured to cooperate with the plurality of blood pressure measuring devices to determine respective blood pressure measurements for each patient extremity, selectively determine differences between the blood pressure measurements, and generate an indication of a probable vascular aneurysm based upon a determined difference between at least two of the blood pressure measurements reaching a vascular aneurysm threshold value. | 10-20-2011 |
| 20110263989 | METHODS AND APPARATUS FOR DETERMINING A CENTRAL AORTIC PRESSURE WAVEFORM FROM A PERIPHERAL ARTERY PRESSURE WAVEFORM - A method is provided for determining a central aortic pressure (AP) wave-form for a subject. The method includes measuring a peripheral artery pressure (PAP) waveform from the subject, employing a distributed model to define a pressure-to-pressure transfer function relating PAP to AP and a pressure-to-flow transfer function relating PAP to a central arterial flow in terms of the same unknown parameters, estimating the unknown parameters by finding the pressure-to-flow transfer function, which when applied to the measured PAP waveform, minimizes the magnitude of the central arterial flow waveform during diastole, and applying the pressure-to-pressure transfer function with the estimated parameters to determine an AP waveform for the subject. | 10-27-2011 |
| 20110263990 | RAPID NON-INVASIVE BLOOD PRESSURE MEASURING DEVICE - A measurement device for generating an arterial volume-indicative signal includes an exciter and a detector. The exciter is adapted to receive an oscillating signal and generate a pressure wave based at least in part on the oscillating signal on the artery at a measurement site on a patient. The pressure wave includes a frequency. The detector is placed sufficiently near the measurement site to detect a volumetric signal indicative of arterial volume of the patient. | 10-27-2011 |
| 20110263991 | METHOD AND APPARATUS FOR CONTROL OF NON-INVASIVE PARAMETER MEASUREMENTS - Improved methods and apparatus for non-invasively assessing one or more parameters associated with fluidic systems such as the circulatory system of a living organism, when such parameters are potentially affected by other concurrent events. In one exemplary embodiment, apparatus and methods for compensating for occlusive events (e.g., pressure cuff inflation) occurring ipsilateral to the location of parameter measurement are disclosed. Upon passive detection of signal degradation resulting from the event, the apparatus selectively enters a “wait state” wherein further processing of the hemodynamic data is suspended until the degrading event subsides. This behavior mitigates any adverse effects the event might have on the accuracy of the representation of the measured hemodynamic parameter generated by the system. In another exemplary embodiment, the measured data is analyzed in order to classify the type of event (e.g., occlusive or other), such classification allowing the system to appropriately tailor its response to the event. | 10-27-2011 |
| 20110275943 | Arterial Pressure-Based, Automatic Determination of a Cardiovascular Parameter - One or more cardiovascular parameters is estimated as a function of the arterial pressure waveform, in particular, using at least one statistical moment of a discrete representation pressure waveform having an order greater than one. Arterial compliance, the exponential pressure decay constant, vascular resistance, cardiac output, and stroke volume are examples of cardiovascular parameters that can be estimated using various aspects of the invention. In one embodiment of the invention, not only are the first four moments (mean, standard deviation, skewness, and kurtosis) of the pressure waveform used to estimate the cardiovascular parameter(s) of interest, but also heart rate, statistical moments of a set of pressure-weighted time values, and certain anthropometric patient measurements such as age, sex, body surface area, etc. | 11-10-2011 |
| 20110288419 | ARTERIAL PULSE DECOMPOSITION ANALYSIS FOR VITAL SIGNS DETERMINATION - determining physiological life signs, with a sensor that is in contact with the surface of a patient's skin at point proximate an artery, and measuring arterial blood vessel displacement and/or blood pressure changes. A data stream of measurements of is collected and a set of parameters from the collected data, a number of physiological life signs parameters, is extracted from the data. The physiological life signs that can be extracted include heart rate, breathing rate, systolic blood pressure, and diastolic blood pressure. | 11-24-2011 |
| 20110288420 | BLOOD PRESSURE MEASURING DEVICE AND BLOOD PRESSURE MEASURING METHOD - A blood pressure measuring device includes a blood flow velocity sensor detecting a blood flow within the body; a blood flow velocity sensor driver driving the blood flow velocity sensor part; a blood flow velocity sensor signal calculating part controlling the blood flow velocity sensor driver and the blood flow velocity sensor, and obtaining the blood flow velocity within the body; a vascular diameter sensor detecting a difference in reflection arrival time for the vascular wall in the body; a vascular diameter sensor driver driving the vascular diameter sensor; a vascular diameter sensor signal calculating part controlling the vascular diameter sensor driver and the vascular diameter sensor, and obtaining the vascular diameter in the body; and a blood pressure signal calculater using a result of a calculation by the blood flow velocity sensor signal calculater and the vascular diameter sensor signal calculater to obtain the blood pressure of the subject. | 11-24-2011 |
| 20110288421 | BLOOD PRESSURE MONITOR - The invention provides a method for measuring a blood pressure value of a user featuring the following steps: 1) generating optical, electrical, and acoustic waveforms with, respectively, optical, electrical, and acoustic sensors attached to a single substrate that contacts a user; 2) determining at least one parameter by analyzing the optical and acoustic waveforms; and 3) processing the parameter to determine the blood pressure value for the user. | 11-24-2011 |
| 20110295128 | BLOOD-PRESSURE SENSOR - A blood-pressure sensor includes a substrate, a first electrode, a magnetization fixed layer, a nonmagnetic layer, a magnetization free layer, and a second electrode. The substrate is bent to generate a tensile stress at least in a first direction. The first electrode is provided on the substrate. The magnetization fixed layer has magnetization to be fixed in a second direction, and is provided on the substrate. The nonmagnetic layer is provided on the magnetization fixed layer. The magnetization free layer has a magnetization direction which is different from the first direction and from a direction perpendicular to the first direction. The second electrode is provided on the magnetization free layer. | 12-01-2011 |
| 20110301472 | METHOD AND APPARATUS FOR DETERMINING AND/OR MONITORING A PHYSICAL CONDITION OF A PATIENT BASED ON AN AMPLITUDE OF A PRESSURE SIGNAL - A method for determining and/or monitoring quantities, in particular cardiovascular quantities, relating to a patient's condition, and an apparatus for measuring an amplitude of a cardiac pressure signal are disclosed. The amplitude of the pressure signal may be detected with the aid of a pressure sensor of a blood treatment apparatus, and its magnitude may be corrected by the contribution of the blood pump of the blood treatment apparatus so as to determine the amplitude of the cardiac pressure signal of the patient. The value of the amplitude of the pressure signal thus determined may subsequently be evaluated. | 12-08-2011 |
| 20110313300 | DETECTION OF NOISE DURING HEART BEAT VARIATION EVALUATION - A medical device obtains an oscillometric measurement associated with a patient's non-invasive blood pressure reading. The device determines a stability measure for at least one pair of pulses included in the oscillometric measurement, compares the stability measure to a threshold, and excludes the pair of pulses from an evaluation of heart beat variation when the stability measure fails to meet the threshold. | 12-22-2011 |
| 20110313301 | BLOOD PRESSURE IRREGULARITY SENSING - A medical device obtains a set of data associated with a patient's non-invasive blood pressure cycle reading, provides a representation of a pulse interval map on the display screen based on the set of data, the pulse interval map including one or more interval data points representing intervals between heat beats, and alerts a caregiver if one or more of the interval data points fall outside an interval bound. The medical device can also plot a pulse volume map on the display screen based on the set of data, the pulse volume map including one more volume data points representing volumes associated with given heat beats, and alert a caregiver if one or more of the volume data points fall outside a volume bound. | 12-22-2011 |
| 20110319770 | FUNCTION ADDING MODULE - A function adding module includes a connection portion for connection to an existing blood pressure meter with an air tube and a connection portion for connection to a cuff with an air tube. The function adding module calculates a pressure value by detecting a change in internal pressure of the cuff using an embedded pressure sensor. The function adding module has a memory function and stores the calculated blood pressure value in a memory. | 12-29-2011 |
| 20110319771 | VITAL LUMINAL PART EVALUATING APPARATUS - A pressure vessel is provided with an annular inflation bag and an annular inflation bag for sealing the pressure vessel at intermediate positions of brachium and antebrachium of the live body in longitudinal direction of the arms of the live body, and is configured to permit a change of an internal pressure therein over a pressure range a lower limit of which is a negative value, while a portion of the brachium and antebrachium between first and second positions in the longitudinal direction is accommodated in the pressure vessel, so that the pressure vessel can be comparatively small-sized even where arterial vessel (luminal part) of a comparatively large diameter is accommodated in the pressure vessel, whereby the physical and mental burden on the subject person can be reduced. | 12-29-2011 |
| 20120029363 | SYSTEMS AND METHODS FOR IMPROVED COMPUTATION OF DIFFERENTIAL PULSE TRANSIT TIME FROM PHOTOPLETHYSMOGRAPH SIGNALS - Systems and methods for processing photoplethysmograph (PPG) signals to determine a differential pulse transit time (DPTT) are disclosed. Sensors may be used to obtain first and second PPG signals from a subject. The sensors may be placed at different locations on the subject's body. A first algorithm may be performed on the PPG signals or on signals derived from them to obtain a DPTT. A corresponding confidence measure may be determined and if the confidence measure falls within a first numerical range, the calculated DPTT may be used. On the other hand, if the confidence measure falls within a second numerical range, an alternative algorithm may be performed on the PPG signals or on signals derived from them and the DPTT obtained using the alternative algorithm may be used. The DPTT may be used to perform continuous or periodic measurements of blood pressure. | 02-02-2012 |
| 20120029364 | MEASUREMENT OF CARDIAC CYCLE LENGTH AND PRESSURE METRICS FROM PULMONARY ARTERIAL PRESSURE - Various techniques for measuring cardiac cycle length and pressure metrics based on pulmonary artery pressures are described. One example method described includes identifying a point within a derivative signal of a cardiovascular pressure signal without reference to electrical activity of a heart, initiating a time window from the identified point in the derivative signal, identifying a point within the cardiovascular signal within the time window, and determining at least one of a systolic pressure or diastolic pressure based on the identified point. | 02-02-2012 |
| 20120029365 | MEASUREMENT OF CARDIAC CYCLE LENGTH AND PRESSURE METRICS FROM PULMONARY ARTERIAL PRESSURE - Various techniques for measuring cardiac cycle length and pressure metrics based on pulmonary artery pressures are described. One example method described includes identifying a point within a derivative signal of a cardiovascular pressure signal without reference to electrical activity of a heart, initiating a time window from the identified point in the derivative signal, identifying a point within the cardiovascular signal within the time window, and determining at least one of a systolic pressure or diastolic pressure based on the identified point. | 02-02-2012 |
| 20120065525 | PRESSURE GAUGE, BLOOD PRESSURE GAUGE, METHOD OF DETERMINING PRESSURE VALUES, METHOD OF CALIBRATING A PRESSURE GAUGE, AND COMPUTER PROGRAM - A pressure gauge for determining at least one pressure value describing a pressure of a fluid flowing in a pulsating manner in a phase of the pulsating flow, includes a pulse wave characterizer. The pulse wave characterizer is configured to obtain transmit time information of a pulse wave, and amplitude information of the pulse wave. The pressure gauge additionally includes a pressure value determiner configured to obtain a first pressure value describing a pressure of the fluid in a first phase, on the basis of the transmit time information and while using a mapping. The pressure value determiner is further configured to obtain a second pressure value describing a pressure of the fluid in a second phase, on the basis of the first pressure value and the amplitude information while using a mapping. | 03-15-2012 |
| 20120065526 | PIEZOELECTRIC SENSOR FOR MEASURING PRESSURE FLUCTUATIONS - The invention relates to a piezoelectric sensor for the improved measurement of mechanical variables such as force, pressure or measurement variables which are derived there from, particularly a PVDF film sensor having an improved sensitivity and temperature stability of the measurement signal for pressure measurements that vary in time and/or space, and for the one- and two-dimensional determination of the position and propagation velocity of pressure fluctuations and pressure waves with a single measurement sensor at a measurement location. A preferred field of application of the invention is the non-invasive, low strain and continuous measurement of the pulse rate and the systolic and diastolic blood pressure of humans and animals by determining the velocity and the signal form of the pulse waves. The object of the invention is to allow the measurements of the blood pressure and the pulse rate, for example even in the case of emergency patients having only a very low blood pressure and patients having circulatory disorders in the extremities, for example patients which have developed diabetes or the “smoker's leg”, by using only one sensor at a measurement location due to the improved measurement sensitivity of the piezoelectric sensor, with the result that the continuous application of a pressurized jacket for continuously measuring and monitoring the blood pressure is not necessary. The present invention solves this problem in that a plurality of parallel strips of a piezoelectric material ( | 03-15-2012 |
| 20120071767 | PULMONARY ARTERY PRESSURE ESTIMATOR - A pulmonary artery pressure estimator attaches a plurality of acoustic sensors to a patient so as to measure a second heart sound. The sensors are arranged so that an A2 component of the second heart sound is maximized from at least one of the sensors and a P2 component is maximized from at least another one of the sensors. Electrodes are also attached to the patient so as to measure a cardiac interval. A splitting interval is derived from the A2 and P2 components, which is normalized by the cardiac interval. The normalized splitting interval provides an estimation of the pulmonary artery pressure (PAP). | 03-22-2012 |
| 20120078123 | PULSE WAVE ANALYZER AND BLOOD PRESSURE ESTIMATOR USING THE SAME - In a pulse wave analyzer, an ECG signal and a pulse wave signal are detected from an object to be analyzed. A plurality of feature points are extracting from the acquired ECG signal, the feature points appearing in a waveform of the ECG signal. The acquired pulse wave signal is segmented into a plurality of pulse wave signal pieces based on times at which the feature points appear. Each of the pulse wave signal pieces is segmented every heart beat. A reference pulse wave is calculated based on the plurality of pulse wave signal pieces, by multiplying the pulse wave signal pieces by coefficients and averaging the pulse wave signal pieces multiplied by the coefficients. The reference pulse wave is used to estimate the blood pressure of the object. | 03-29-2012 |
| 20120108984 | INTEGRATED PATIENT CARE - A therapy regimen, e.g., a contingent medication prescription, may be created and automatically distributed to a patient via an integrated patient care system. A clinician may create therapy instructions by at least associating patient conditions with one or more therapy regimens, e.g., medication prescriptions. In some examples, the integrated patient care system may present historical condition data to the clinician to aid the clinician with creating and/or updating the therapy instructions specific to the patient. A therapy module of the integrated patient care system may use the therapy instructions to automatically select a therapy regimen from the therapy instructions based on a patient condition detected based on a sensed physiological parameter. The physiological parameter of the patient may be sensed by an implanted or external sensor. In some examples, the therapy regimen can be presented to the patient according to a predetermined schedule or in response to the detected condition. | 05-03-2012 |
| 20120108985 | CUFFLESS BLOOD PRESSURE MONITOR - A cuffless blood pressure monitor is revealed. The cuffless blood pressure monitor includes a pressure detection module, a signal processing module and a display module. The pressure detection module detects blood pressure to generate a blood pressure pulse signal. The signal processing module processes the blood pressure pulse signal to generate a measurement result that is displayed by the display module. The cuffless blood pressure monitor measures continuous blood pressure pulse signals, processes the blood pressure pulse signals by the signal processing module, and calculates the measurement result for real-time measurement of blood pressure. A measurement point on the user is pressed by a soft pressure-transferring medium so that the user won't feel uncomfortable. Moreover, the cuffless blood pressure monitor is compact and portable. | 05-03-2012 |
| 20120116235 | SYSTEMS AND METHODS FOR PRODUCING AUDIBLE INDICATORS THAT ARE REPRESENTATIVE OF MEASURED BLOOD PRESSURE - Systems and methods are disclosed for producing audible indicators that are based on a subject's measured blood pressure. Audible properties of the indicators are processed to represent blood pressure. For example, the duration or volume of the audible indicators may be varied based on the values of the subject's blood pressure. The audible indicators may further be varied based on the subject's blood pressure's deviation from a normal blood pressure and/or previously calculated blood pressure. For example, the audible indicators may be indicative of changes in the subject's blood pressure over time. The audible indicators representing blood pressure may be synchronized with other audible indicators that represent other physiological parameters of the subject, such as, the subject's heart rate. | 05-10-2012 |
| 20120123280 | METHOD FOR MEASURING ARTERIAL PRESSURE AND A DEVICE FOR THE IMPLEMENTATION OF SAME - A method for measuring arterial pressure involves hydraulically separating a static pressure source from a body area situated opposite thereto and containing an artery by placing a rigid separating element between the two and along the artery. With the aid of the separating element, pulse waves are converted into pressure waves, which run along said element on the first side thereof, and the passage of the pulse waves is detected with the aid of the pressure waves. A device for measuring arterial pressure comprises a rigid separating element which has a first contact surface for interacting with the body and a second contact surface which is opposite to the first and is used for interacting with the static pressure source. A push-type pressure gauge with a contact area that is embedded into one of the two contact surfaces of the separating element and a pulse wave detector are disposed inside the rigid separating element. The sensing element of the detector is located on the first contact surface. | 05-17-2012 |
| 20120136261 | Systems and methods for calibrating physiological signals with multiple techniques - Systems and methods are disclosed herein for calibrating the calculation of physiological parameters. Two or more calibration techniques may be used to determine a relationship between physiological measurements and a desired physiological parameter, such as a relationship between differential pulse transit time (DPTT) and blood pressure. Different calibration techniques may be used in a serial fashion, one after the other, or in a parallel fashion, with different weights accorded to each calibration technique. When physiological or other changes occur, the calibration data may be stored for later use and new calibration data may be generated. | 05-31-2012 |
| 20120143067 | SYSTEMS AND METHODS FOR DETERMINING WHEN TO MEASURE A PHYSIOLOGICAL PARAMETER - Systems and methods are provided for determining when to update a blood pressure measurement. The value of a physiological metric may be monitored and compared to a reference value. A patient monitoring system may compute a difference between a monitored metric and a reference value, and compare the difference to a threshold value to determine whether to update a blood pressure measurement. The threshold value may be constant or variable, and may depend on the monitored metric. | 06-07-2012 |
| 20120143068 | COMPUTERIZE HEALTH MANAGEMENT METHOD AND HEALTH MANAGEMENT ELECTRONIC DEVICE - A computerized health management method and a health management electronic device are provided. The computerized health management method includes the following steps. A blood pressure curve of a user is measured. A systolic pressure and a diastolic pressure of the blood pressure curve are calculated by a microprocessor. A high blood pressure risk level of the user is analyzed by the microprocessor according to the systolic pressure and the diastolic pressure. A cardiovascular disease risk level of the user is analyzed by the microprocessor according to the high blood pressure risk level. A measuring frequency for measuring the blood pressure is suggested to the user by the microprocessor according to the high blood pressure risk level or the cardiovascular disease risk level. | 06-07-2012 |
| 20120165685 | PLASMAPHERESIS DONOR DISPLAY AND METHOD OF USE - Certain examples provide a blood collection system including an operator user interface to allow an operator to configure the system for a blood collection procedure from a donor. The system also includes a donor display, separate from the operator user interface, arranged in the system to be within view of the donor who is to donate via the system. The donor display is to display information and instruction to the donor. The information and instruction include a first indicator regarding a progress of the blood collection procedure for the donor and a second indicator including a visual instruction to the donor regarding the blood collection procedure. The system includes a processor and a memory. The processor is to execute instructions stored in the memory to process input from and provide output to the operator user interface and the donor display. | 06-28-2012 |
| 20120165686 | BLOOD VESSEL FUNCTION INSPECTING APPARATUS - It is provided a blood vessel function inspecting apparatus including: a blood vessel diameter measuring portion configured to measure a diameter of a blood vessel; a blood vessel wall thickness measuring portion configured to measure a wall thickness of the blood vessel; and a blood vessel function index value calculating portion configured to calculate a function index value for diagnosing the blood vessel of its function, after releasing of the blood vessel from blood flow obstruction, by dividing an amount of dilatation of said diameter of the blood vessel continuously measured by said blood vessel diameter measuring portion, by the wall thickness measured by said blood vessel wall thickness measuring portion. | 06-28-2012 |
| 20120179052 | Biodegradable Fluid Delivery Device - An assembly for a fluid transfer system includes: a connector having a proximal end and an opposite distal end connected by an inner passage; and a container having an internal fluid reservoir. The connector is coupled to the internal fluid reservoir of the container to form a series fluid connection between the inner passage and the internal fluid reservoir, and the connector and the container are made of a biodegradable material. | 07-12-2012 |
| 20120179053 | APPARATUS FOR MEASURING A PROPAGATION VELOCITY OF A BLOOD PRESSURE WAVE - An apparatus for measuring the propagation velocity of a pressure wave comprises a first sensor of cutaneous vibration to measure a vibration generated in a first application point, creating a corresponding first signal, and a second sensor of cutaneous vibrations to measure a local cutaneous vibration generated in second point of an arterial vessel, creating a corresponding second signal caused by the deformation of the vessel responsive to the progression of the pressure wave in the vessel. A control unit detects on the first and second signal respectively a first instant time T | 07-12-2012 |
| 20120190991 | System and Method for Detecting a Clinically-Significant Pulmonary Fluid Accumulation Using an Implantable Medical Device - Techniques are provided for detecting a clinically-significant pulmonary fluid accumulation within a patient using a pacemaker or other implantable medical device. Briefly, the device detects left atrial pressure (LAP) within the patient and tracks changes in the LAP values over time that are indicative of possible pulmonary fluid accumulation within the patient. The device determines whether the changes in LAP values are sufficiently elevated and prolonged to warrant clinical intervention using, e.g., a predictor model-based technique. If the fluid accumulation is clinically significant, the device then generates warning signals, records diagnostics, controls therapy and/or titrates diuretics. False positive detections of pulmonary edema due to transients in LAP are avoided with this technique. Pulmonary artery pressure (PAP)-based techniques are also described. | 07-26-2012 |
| 20120220882 | Device for the Non-Invasive Determination of Arterial Blood Pressure | 08-30-2012 |
| 20120232411 | PRESSURE MEASURING SYSTEM, PRESSURE MEASURING SENSOR ASSEMBLY AND A METHOD OF MEASURING A PRESSURE - A pressure measuring System ( | 09-13-2012 |
| 20120245476 | IMPLANTABLE MEDICAL DEVICE - An implantable medical device includes an integrated or connectable implantable three-dimensional acceleration sensor, and a ballistocardiogram (BCG) capturing unit that is connected or connectable to the acceleration sensor. The BCG evaluation unit processes an acceleration signal provided by the acceleration sensor and derives a BCG from the 3D accelerometer output signal. A BCG evaluation unit is connected to the BCG capturing unit, and is designed to evaluate a BCG provided by the BCG capturing unit and supply an output signal representing stroke volume. | 09-27-2012 |
| 20120245477 | MAGNETO-RESISTIVE EFFECT DEVICE, MAGNETIC HEAD GIMBAL ASSEMBLY, MAGNETIC RECORDING/REPRODUCTION DEVICE, STRAIN SENSOR, PRESSURE SENSOR, BLOOD PRESSURE SENSOR, AND STRUCTURAL HEALTH MONITORING SENSOR - According to one embodiment, a magneto-resistive effect device, includes a stacked body stacked on a substrate, a pair of first electrodes that feeds current to the stacked body, a strain introduction member, and a second electrode for applying a voltage to the strain introduction member. The stacked body includes a first magnetic layer that includes one or more metals selected from the group consisting of iron, cobalt, and nickel, a second magnetic layer stacked on the first magnetic layer, having a composition that is different from the first magnetic layer, and a spacer layer disposed between the first magnetic layer and the second magnetic layer. | 09-27-2012 |
| 20120259235 | Systems and Methods for Monitoring Heart Rate and Blood Pressure Correlation - Systems and methods are provided for monitoring a correlation between heart rate and blood pressure in a patient. When a characteristic of the correlation exceeds a threshold, a patient status indicator signal is sent to a monitoring device. In some embodiments, the patient status indicator signal indicates a particular medical condition or alerts a care provider to a change in status. In some embodiments, the heart rate signal is used to improve a blood pressure estimate generated by a different signal. In some embodiments, the heart rate, blood pressure and correlation signals are used in a predictive mathematical model to estimate patient status or outcome. | 10-11-2012 |
| 20120277599 | MEASUREMENT OF CARDIAC CYCLE LENGTH AND PRESSURE METRICS FROM PULMONARY ARTERIAL PRESSURE - A method and apparatus for monitoring a cardiovascular pressure signal in a medical device that includes comparing the sensed pressure signal to a first pressure threshold, identifying a first sense greater than the first pressure threshold, determining a metric of the pressure signal in response to the identified first sense, comparing the sensed pressure signal to a second pressure threshold not equal to the first pressure threshold in response to the identified first sense, identifying a second sense, subsequent to the first sense, greater than the second pressure threshold, identifying a third sense, subsequent to the first sense, greater than the first pressure threshold, and determining a cycle length corresponding to electrical activity of a heart in response to one of the first sense and the third sense or the second sense and the third sense. | 11-01-2012 |
| 20120277600 | MEASUREMENT OF CARDIAC CYCLE LENGTH AND PRESSURE METRICS FROM PULMONARY ARTERIAL PRESSURE - A method and apparatus for monitoring a cardiovascular pressure signal in a medical device that includes determining whether the sensed pressure signal is greater than a first pressure threshold, determining a first metric of the pressure signal in response to the sensed pressure signal being greater than the first pressure threshold, determining whether the sensed pressure signal is greater than a second pressure threshold not equal to the first pressure threshold, determining a second metric of the pressure signal in response to the sensed pressure signal being greater than the first pressure threshold, and determining at least one of a systolic pressure or a diastolic pressure, wherein the at least one of a systolic pressure or a diastolic pressure is determined based on the first metric in response to the pressure signal not being greater than the second threshold, and based on the second metric in response to the pressure signal being greater than the second threshold. | 11-01-2012 |
| 20120283580 | VERIFICATION OF PRESSURE METRICS - An example system may include at least one pressure sensor configured to measure a cardiovascular pressure signal and another medical device configured to measure an electrical depolarization signal of the heart. The system determines a plurality of cardiovascular pressure metrics based on the measured cardiovascular pressure signal, including at least one cardiovascular pressure metric indicative of a timing of at least one cardiac pulse. The system also determines a metric indicative of a timing of at least one heart depolarization within the measured electrical depolarization signal. The system compares the timing of the at least one cardiac pulse to the timing of the at least one depolarization, and determines whether to discard the plurality of cardiovascular pressure metrics based on whether the timings substantially agree. | 11-08-2012 |
| 20120283581 | DEVICES, A COMPUTER PROGRAM PRODUCT AND A METHOD FOR DATA EXTRACTION - A monitoring device receives a measurement signal obtained by a pressure sensor in an extracorporeal fluid system, such as an extracorporeal blood circuit for a dialysis machine which is in contact with a vascular system of a subject via a fluid connection. The monitoring device processes the measurement signal to identify pressure data that represents pulses originating from a first physiological phenomenon in the subject, excluding the heart of the subject. The first physiological phenomenon may be any of reflexes, voluntary muscle contractions, non-voluntary muscle contractions, a breathing system of the subject, an autonomous system of the subject for blood pressure regulation, or an autonomous system of the subject for body temperature regulation. The monitoring device may detect, present, track or predict a disordered condition of the subject using the pressure data, or monitor the integrity of the fluid connection based on the pressure data. | 11-08-2012 |
| 20120283582 | SYSTEMS AND METHODS FOR DETERMINING LOCATION OF AN ACCESS NEEDLE IN A SUBJECT - Systems and methods for epicardial electrophysiology and other procedures are provided in which the location of an access needle may be inferred according to the detection of different pressure frequencies in separate organs, or different locations, in the body of a subject. Methods may include inserting a needle including a first sensor into a body of a subject, and receiving pressure frequency information from the first sensor. A second sensor may be used to provide cardiac waveform information of the subject. A current location of the needle may be distinguished from another location based on an algorithm including the pressure frequency information and the cardiac waveform information. | 11-08-2012 |
| 20130006125 | Personalized Activity Monitor and Weight Management System - A weight management system comprised of a body worn device which interfaces periodically with a computer. The established weight goals of the user are translated by the computer into daily activity targets and downloaded into the device. The device monitors the user's activity, offering progress status toward the daily activity target. Further, the device alerts the user of excessive sedentary periods which depress metabolic indicators. The activity targets, allowed length of sedentary periods and suggested activities to reach goal are specific to the individual based on their biometrics and living environment. The computer provides historical tracking of activity for motivational and coaching purposes. | 01-03-2013 |
| 20130006126 | HEMODYNAMIC MONITOR AND METHOD OF HEMODYNAMIC MONITORING - An apparatus and method for determining stroke volume. The apparatus receives an arterial pressure waveform and is arranged to correct a part of the pressure waveform that relates to a heart beat for an influence of an ectopic heart beat, of atrial fibrillation on the pressure waveform or of changes in the pressure waveform's baseline. The apparatus also comprising means arranged to calculate the stroke volume from the corrected waveform. | 01-03-2013 |
| 20130006127 | SYSTEMS AND METHODS FOR MODEL-BASED ESTIMATION OF CARDIAC OUTPUT AND TOTAL PERIPHERAL RESISTANCE - The methods and systems for estimating cardiac output and total peripheral resistance include observing arterial blood pressure waveforms to determine intra-beat and inter-beat variability in arterial blood pressure and estimating from the variability a time constant for a lumped parameter beat-to-beat averaged Windkessel model of the arterial tree. Uncalibrated cardiac output and uncalibrated total peripheral resistance may then be calculated from the time constant. Calibrated cardiac output and calibrated total peripheral resistance may be computed using calibration data, assuming an arterial compliance that is either constant or dependent on mean arterial blood pressure. The parameters of the arterial compliance may be estimated in a least-squares manner. | 01-03-2013 |
| 20130041270 | BLOOD PRESSURE MEASURING DEVICE AND SYSTEM WITH AUTOMATIC SELF-EXAMINATION AND SELF-CALIBRATION FUNCTIONS - A blood pressure measuring system with automatic self-examination and self-calibration functions, which utilizes an examining and calibrating unit to automatically compare pressure information detected by a signal detection unit with an original factory calibration value for pressure, to self-calibrate the blood pressure measuring system, wherein the examining and calibrating unit can be arranged in a blood pressure measuring device or in an external electronic device, for providing users a method to confirm accuracy of the blood pressure measuring system to prevent serious consequence caused by miscalculations of blood pressure and physiological values. Accordingly, original factory calibration can be skipped to save time and money; calibration and examination processes are simplified and more convenient. | 02-14-2013 |
| 20130072806 | System for Cardiac Arrhythmia Detection and Characterization - A system for heart performance characterization and abnormality detection comprises an input processor and at least one signal processor. The input processor receives, sampled data representing a patient blood pressure signal and a concurrently acquired electrocardiogram (ECG) signal representing heart electrical activity of the patient. The at least one signal processor, synchronizes the patient blood pressure signal and the heart electrical activity signal, identifies at least two points of a heart electrical activity signal cycle, integrates signal data values representing the amplitude of the patient blood pressure signal of a segment between the identified two points to derive an integral value over time duration of the segment representing an area under the blood pressure signal waveform between the identified two points and in response to the derived integral value, initiates generation of a message associated with a medical condition of the patient. | 03-21-2013 |
| 20130072807 | HEALTH MONITORING APPLIANCE - A monitoring system for a person includes one or more wireless nodes; and a wearable patch or bandage appliance secured to the person' skin and in communication with the one or more wireless nodes, wherein the patch or bandage appliance monitors and transmits patient vital signs to the wireless nodes. | 03-21-2013 |
| 20130096443 | PUSH-TYPE DISCHARGE ASSEMBLY OF BLOOD PRESSURE MONITOR - A push-type discharge assembly of a blood pressure monitor includes a valve base, a spring, a driven element, a restricting element, and a pressing element. The valve base is provided with an accommodating trough and an intake pipe. The spring is disposed in the accommodating trough. The driven element abuts against one end of the spring. The driven element is formed with a protrusion. The restricting element covers the accommodating trough. The restricting element has a central through-hole and is formed with a restricting notch. The pressing element passes through the central through-hole. The pressing element has a sealing body and a driving portion disposed on a lower edge of the sealing body to drive the driven element. When the pressing element is pressed downwards, the sealing body moves downwards to form a discharge channel between the pressing element and the central through-hole. | 04-18-2013 |
| 20130096444 | SYSTEM AND METHOD FOR DYNAMICALLY ADJUSTING PATIENT THERAPY - A system and method of managing therapy provided to patients in an institution. The system monitors all aspects of the medication delivery to a patient, as well as other information related to the patient, such as values of vital signs, laboratory results and patient factors such as history, diagnosis, allergies and the like. The system includes one or more databases of information, including institutionally developed rules, guidelines and protocol representing the best medical practices of the institution. The system provides alerts and/or recommendations based on the application of the rules to the information being monitored, and alerts care givers accordingly, providing for dynamic adjustment of the patient's therapy. The system also monitors the status of the alerts, and if no action is taken in a selected period of time, may escalate the priority of the alert and/or halt the delivery of medication to the patient until the alert is resolved. | 04-18-2013 |
| 20130102909 | METHOD AND APPARATUS FOR DETERMINING A CENTRAL AORTIC PRESSURE WAVEFORM - A method is provided for determining a central aortic pressure waveform. The method includes: measuring two or more peripheral artery pressure waveforms; analyzing the signals so as to extract common features in the measured waveforms; and determining an absolute central aortic pressure waveform based on the common features. | 04-25-2013 |
| 20130109979 | NON-INVASIVE INTRACRANIAL MONITOR | 05-02-2013 |
| 20130144175 | PERSONAL HEALTH INFORMATION IDENTIFICATION TAG - A smart identification tag system comprises a helmet and an identification tag. The helmet defines a headspace adapted to receive a wearer's head. A sensor assembly is disposed in the headspace and comprises a sensor capable of capturing data and a wireless transceiver in communication with the sensor and adapted to transmit a wireless signal indicative of data captured by the sensor. The identification tag comprises a wireless transceiver adapted to receive the signal from the helmet, and a non-transitory memory in communication with the wireless transceiver and adapted to store the received data. The helmet is adapted to be worn by a wearer, and the identification tag is adapted to be carried on the person of the wearer, such that information captured by the sensor assembly is transmitted to the identification tag and stored therein. The identification tag may further store personal health information of the wearer. | 06-06-2013 |
| 20130144176 | NON-INVASIVE BLOOD PRESSURE SENSOR - A non-invasive pressure measurement device measures pressure of fluid in a conduit via a piezoelectric transducer positioned proximate to the conduit having a fluid passing therethrough. The piezoelectric transducer is in communication with the conduit via a plate member having a protrusion extending outward from one side of the member. In one application, the device continuously measures blood pressure without the need for an inflatable cuff. Also, the device can detect and measure heart beat pulses from the fluid and utilize heart beat pulse information to provide further characteristics pertaining to the fluid in the conduit. | 06-06-2013 |
| 20130150735 | METHOD AND DEVICE FOR MEASURING PARAMETERS OF CARDIAC FUNCTION - A device for non-invasively measuring at least one parameter of a cardiac blood vessel in a patient is provided. The device comprises at least one light source that emits light in the 400 nm to 1000 nm wavelength range; at least one photodetector adapted to receive light emitted by the light source and generate an output based on the received light, wherein said light is reflected from or transmitted through tissue of the patient, the output of said photodetector being correlated with a parameter of the blood vessel; and at least one probe for facilitating delivery of light from the light source to an external tissue site on the patient in the proximity of the cardiac blood vessel and receipt of light by the photodetector. A system and methods of monitoring/measuring cardiac parameters utilizing the device and/or system are also provided. | 06-13-2013 |
| 20130150736 | AUTOMATIC METHOD FOR MEASURING AND PROCESSING BLOOD PRESSURE - The present invention concerns an automatic method, as well as the related system and the tools allowing the same to be executed, for measuring and processing blood pressure starting from a detected pressure signal, the method operating in the time domain for discriminating whether the detected signal is an adequate measurement or not and, where it is not, time domain analysis automatically selects a low-pass filter to, possibly iteratively, apply to the detected pressure signal for having correct values and wave form of the blood pressure. | 06-13-2013 |
| 20130158417 | METHOD, APPARATUS AND COMPUTER PROGRAM FOR AUTOMATIC NON-INVASIVE BLOOD PRESSURE MEASUREMENT - A method, apparatus and computer program product are disclosed for non-invasively determining blood pressure of a subject. To improve the specificity of automatic blood pressure determinations in a patient monitor provided with a non-invasive blood pressure determination unit, a physiological index indicative of sympathetic activity is derived from a subject, variations in the physiological index are monitored, and the blood pressure determination unit is instructed to initiate blood pressure determination when the variations fulfill a predetermined condition. | 06-20-2013 |
| 20130165800 | ARM-WORN BLOOD PRESSURE MONITOR - A method employed in a prior art arm-worn blood pressure monitor to measure the height position of the heart has been an indirect method that merely estimates the position of the heart, and therefore has had the problems that the measurement accuracy and the reliability of the measurement are low, and that the measuring position is awkward and it is difficult to achieve correct position alignment. An arm-worn blood pressure monitor includes a cuff, a microwave transmitting unit for radiating a microwave onto a human subject, a microwave receiving unit for receiving a reflected wave Doppler-shifted relative to the radiated microwave due to a heartbeat of the subject, and a correct position detector for detecting, based on the reflected wave, whether the cuff worn around an arm of the subject is located in a correct position relative to the position of the heart of the subject. | 06-27-2013 |
| 20130172761 | METHOD, APPARATUS AND PROGRAM FOR THE AUTOMATIC PROCESSING OF BLOOD PRESSURE SIGNALS - The invention concerns an automated method, a system and means for processing the blood pressure from a detected pressure signal, the method operating in the time domain to determine a value (RES) connected to the energy efficiency of the monitored biological system. | 07-04-2013 |
| 20130184595 | METHODS AND APPARATUS FOR DETERMINING ARTERIAL PULSE WAVE VELOCITY - Methods are presented for determining pulse transit time (PTT) and/or pulse wave velocity (PWV) of a subject by application of parametric system identification to proximal and distal arterial waveforms. The two waveforms are measured from the subject. A system is defined that relates the proximal arterial waveform to the distal arterial waveform (or vice versa) in terms of the unknown parameters of a parametric mathematical model. The model parameters are determined from the measured waveforms using system identification. PTT between the proximal and distal arterial sites is then determined from the system model. PWV may also be determined by dividing the distance between measurement sites (D) by PTT. | 07-18-2013 |
| 20130218031 | METHOD AND APPARATUS FOR ESTIMATING A PULSE ARRIVAL TIME VALUE - Method and apparatus for estimating an arrival time (PAT) value of a subject in an automatic and unsupervised fashion from a sequence of electrical impedance tomography (EIT) images. The method comprises: providing an EIT imaging device adapted to record impedance signal distribution within a measurement region of the subject; measuring a sequence of temporally discrete EIT images during a predetermined measuring time period in the measurement region using the EIT imaging device, each EIT image comprising one or a plurality of EIT pixel subsets, each of said one or a plurality of EIT pixel subset representing an impedance value; generating one or a plurality of time series, each of said one or a plurality of time series representing a variation of the impedance value of the sequence of EIT images; and estimating the PAT value from each of said one or a plurality of time series. | 08-22-2013 |
| 20130231577 | MULTIFUNCTIONAL AUSCULTATION SENSOR PAD - Multifunctional pad, including an auscultation sensor configured to detect audio signals of a subject and provide subject audio data; and an electrocardiogram (ECG) sensor configured to detect electrical activity of the subject and provide subject electrical activity data and an optional temperature sensor; wherein the multifunctional pad is configured to be affixed to a skin surface of the subject by an adhesive layer. Also provided is A monitoring system, including an auscultation sensor configured to detect audio signals of a subject and provide subject audio data; an electrocardiogram (ECG) sensor configured to detect electrical activity of the subject and provide subject electrical activity data; one or more monitoring devices; and a connection interface configured to operatively couple the multifunctional pad to the one or more monitoring devices. | 09-05-2013 |
| 20130253341 | SYSTEMS AND METHODS FOR NON-INVASIVE CONTINUOUS BLOOD PRESSURE DETERMINATION - According to some embodiments, systems and methods are provided for non-invasive continuous blood pressure determination. In some embodiments, a PPG signal is received and locations of pulses within the PPG signal are identified. An area within a particular pulse is measured. The area may be of just the upstroke, downstroke or the entire pulse. The area may be measured relative to a time-domain axis or a baseline of the pulse. The pulse may be split into multiple sections and the area of each section may be measured. The area of one portion of the pulse may correspond to systolic blood pressure while the area of another portion may correspond to diastolic blood pressure. Empirical data may be used to determine blood pressure from the measured area by applying calibration data measured by a suitable device. | 09-26-2013 |
| 20130261472 | SYSTEMS, METHODS AND DEVICES FOR MAINTENANCE, GUIDANCE AND/OR CONTROL - Methods, systems, devices and computer program products for providing maintenance, guidance and/or control of certain systems are disclosed. Typically, in some aspects the systems are complex. Also disclosed are methods, systems, devices and computer program products for providing therapeutic guidance for controlling a subject's circulation. One such method comprises the steps of: (i) determining the subject's present and desired circulatory states as a function of at least mean systemic filling pressure (P | 10-03-2013 |
| 20130281868 | BLOOD PRESSURE MEASUREMENT DEVICE - A blood pressure measurement device includes a case, an electrocardiogram electrode, a pulse wave sensor, an estimation portion, and a display portion. The case has a peripheral surface to be held with both hands. The electrocardiogram electrode detects an electrocardiogram signal associated with a movement of a heart through at least one of the hands. The pulse wave sensor detects a pulse wave signal associated with the movement of the heart through a least one of the hands. The estimation portion estimates a blood pressure based on the electrocardiogram signal and the pulse wave signal. The display portion displays the blood pressure estimated by the estimation portion. | 10-24-2013 |
| 20130310700 | SYSTEMS AND METHODS FOR MONITORING THE CIRCULATORY SYSTEM - In accordance with embodiments of the present disclosure, a ballistocardiogram (BCG) sensor is used to detect heart and vascular characteristics of a user, and provide a BCG output indicative of the detected cardiovascular characteristics. The BCG output can be used for various purposes, such as detecting arterial aging. Secondary sensors can be used in conjunction with the BCG and can be used to determine the central arterial blood pressure, when used in conjunction with a peripheral blood pressure measurement. | 11-21-2013 |
| 20130345573 | Adaptive Control of Monitoring Devices - Disclosed herein is a framework for facilitating adaptive control of monitoring devices. In accordance with one aspect, a position detector detects a chest elevation level and provides chest elevation level data. A processor uses the chest elevation level data to determine a heart elevation level with respect to a reference level. A comparator compares the determined heart elevation level with an elevation level of a monitoring device with respect to the reference level. In response to the comparison, a movement system adjusts the elevation level of the monitoring device. | 12-26-2013 |
| 20140012146 | MEASUREMENT APPARATUS, MEASUREMENT METHOD, PROGRAM, STORAGE MEDIUM, AND MEASUREMENT SYSTEM - There is provided a measurement apparatus including a blood pressure calculation unit configured to calculate a blood pressure value based on electrocardiography information relating to an electrocardiogram of a measurement subject and pulse wave information relating to a pulse wave of the measurement subject, and a chest contact measurement unit that includes an electrocardiography measurement unit that is brought into contact with a chest of the measurement subject to measure the electrocardiogram and a pulse wave measurement unit configured to measure the pulse wave from a pulse wave detection site of the measurement subject. | 01-09-2014 |
| 20140018687 | BLOOD PRESSURE MEASURING APPARATUS AND METHOD FOR CALIBRATING CENTRAL BLOOD PRESSURE ESTIMATION PARAMETER - In an ultrasonic blood pressure meter | 01-16-2014 |
| 20140024954 | Device and Method for Detecting Irregular Placement of an Extracorporeal Vascular Access Needle - A device and method for determining intravascular pressure and irregular needle placement in a hemodialysis procedure include analyzing means for automatically deriving venous access pressure (VAP) at a location of venous needle insertion into the patient and determining a ratio of VAP to mean arterial pressure, where the analyzing means determines multiple VAP values over multiple time periods and determines multiple ratios, one for each VAP value. Detecting means compare each ratio to a predetermined standard ratio derived from a moving average of prior VAP ratios, where the detecting means detects irregular needle placement when elevation of the ratio above the standard ratio is indicated. | 01-23-2014 |
| 20140031704 | STRESS-MEASURING DEVICE AND METHOD - The present invention relates to a stress-measuring device ( | 01-30-2014 |
| 20140052008 | HYPERTENSION MONITORING AND NOTIFICATION DEVICE BASED ON CONTEXT INFORMATION - Disclosed is a hypertension monitoring and notification device based on context information, which includes a data gain and storage unit for storing bio information of a user, context data, and weather and health information; a user context analysis unit for deducing context information of the user from the bio information and the context data to analyze context necessary for measuring hypertension; a specific hypertension analysis unit for analyzing specific hypertension using the context information; a blood pressure grade analysis unit for determining a blood pressure grade via the analyzed context information to deduce blood pressure signal light information and to transmit a recommendation content; and a result output and notification unit for outputting and notifying the user and the doctor of the bio information, the blood pressure signal light information, the specific hypertension information, and the context information. | 02-20-2014 |
| 20140058275 | PRESSURE-SENSING MEDICAL DEVICES AND MEDICAL DEVICE SYSTEMS - Medical device systems and methods for making and using medical device systems are disclosed. An example medical device system may include a guidewire. A pressure sensor assembly may be disposed within the guidewire. The pressure sensor assembly may include a pressure sensor and a first optical fiber coupled to the pressure sensor. The first optical fiber may have a first outer diameter. A cable may be coupled to the guidewire. The cable may include a second optical fiber. The second optical fiber may have a second outer diameter greater than the first outer diameter. | 02-27-2014 |
| 20140066788 | METHODS AND APPARATUS FOR DETERMINING PULSE TRANSIT TIME AS A FUNCTION OF BLOOD PRESSURE - A method is provided for determining pulse transit time of a subject as a function of blood pressure. The method includes: measuring a proximal waveform indicative of the arterial pulse at a proximal site of the subject; measuring a distal waveform indicative of the arterial pulse at a distal site of the subject; defining a relationship between the proximal waveform and the distal waveform in terms of unknown parameters of a nonlinear model; determining the unknown parameters of the nonlinear model from the measured proximal waveform and the measured distal waveform; and determining pulse transit time for the subject as a function of blood pressure from the parameters of the nonlinear model. The nonlinear model can account for arterial compliance and peripheral wave reflection, where the arterial compliance depends on blood pressure. | 03-06-2014 |
| 20140073971 | MANAGING PRELOAD RESERVE BY TRACKING THE VENTRICULAR OPERATING POINT WITH HEART SOUNDS - A system and method for managing preload reserve and tracking the inotropic state of a patient's heart. The S1 heart sound is measured as a proxy for direct measurement of stroke volume. The S3 heart sound may be measured as a proxy for direct measurement of preload level. The S1-S3 pair yield a point on a Frank Starling type of curve, and reveal information regarding the patient's ventricular operating point and inotropic state. As an alternative, or in addition to, measurement of the S3 heart sound, the S4 heart sound may be measured or a direct pressure measurement may be made for the sake of determining the patient's preload level. The aforementioned measurements may be made by a cardiac rhythm management device, such as a pacemaker or implantable defibrillator. | 03-13-2014 |
| 20140088445 | Adhesive Transducer Holder - System, methods and apparatus for a disposable transducer mounting device that secures one transducer to a patient. Based on the illustrative embodiments, the holder is of rigid or semi-rigid material that has the ability to secure the transducer via rails and has an adhesive base that is used to secure the transducer and mounting device to the patient at the desired location. | 03-27-2014 |
| 20140107504 | MONITORING SEVERITY AND DURATION OF ABERRANT PHYSIOLOGICAL PARAMETERS DURING A PROCEDURE - Systems and methods are provided for monitoring a patient during a procedure. A physiological parameter of a patient is monitored during a procedure at an associated sensor. Respective cumulative times are measured for which the monitored physiological parameter of the patient meets each of a plurality of threshold values during the procedure. A risk metric is calculated for the patient, representing an effect of monitored physiological parameter on a patient outcome related to the procedure from the measured cumulative times for which the monitored physiological parameter of the patient met each of the plurality of threshold values. | 04-17-2014 |
| 20140114201 | PORTABLE INFORMATION TERMINAL - A mobile information terminal includes: a directional microphone provided with a front port, a diaphragm and an electrode, wherein the microphone includes a front air chamber formed between a flexible thin film which covers an opening of the front port and the diaphragm, and a rear air chamber formed between a case and the electrode by hermetically covering a rear of the electrode with the case. | 04-24-2014 |
| 20140135632 | METHOD AND APPARATUS FOR DETERMINING CARDIAC MEDICAL PARAMETERS FROM SUPRA-SYSTOLIC SIGNALS OBTAINED FROM AN OSCILLOMETRIC BLOOD PRESSURE SYSTEM - A method and apparatus determine certain cardiac medical parameters that are useful is diagnosing cardiovascular disease. The apparatus is designed to carry out the method, which includes the steps of:
| 05-15-2014 |
| 20140142441 | BIOSIGNAL MEASURING DEVICE, BIOSIGNAL MEASURING METHOD AND BIOSIGNAL PROGRAM - A biosignal measuring device has a first information acquisition module, a second information acquisition module, a first calculation module, a second calculation module, a third calculation module, a heartbeat interval estimation module, a determination module, and an output module. The first information acquisition module acquires the pulse wave signal. The second information acquisition module acquires an electrocardiogram signal. The first calculation module calculates a pulse wave velocity based. The second calculation module determines a heartbeat interval. The third calculation module calculates a relationship between pulse wave velocity and the heartbeat interval. The heartbeat interval estimation module estimates an estimated heartbeat interval based on pulse wave velocity and calculated relationship. The determination module determines whether the position of the first and second information acquisition modules has changed based on the heartbeat interval and the estimated heartbeat interval. The output module outputs information. | 05-22-2014 |
| 20140142442 | Audio Feedback for Medical Conditions - An apparatus is disclosed that comprises a sensor to detect a medical condition; a processor to evaluate the signals from the sensor; an input device and read/write medium to record cues that correspond to the various condition(s) detected by the sensor; and an audio output device to play prerecorded audio cues when a particular medical condition is detected. The audio cue provides a unique reminder message to encourage a person to take a certain action that is healthy. | 05-22-2014 |
| 20140148712 | System and Method To Calculate Cardiac Characteristics - A system and method includes reception of a hemodynamic signal, reception of a cardiac impedance signal, identification of a first peak and a second peak of the cardiac impedance signal, identification of a first portion of the hemodynamic signal based on the first peak and a second portion of the hemodynamic signal based on the second peak, and calculation of a cardiac characteristic based on the first portion and the second portion of the hemodynamic signal. | 05-29-2014 |
| 20140155767 | BIOLOGICAL INFORMATION MEASUREMENT APPARATUS, BIOLOGICAL INFORMATION MEASUREMENT SYSTEM, BIOLOGICAL INFORMATION MEASUREMENT METHOD, AND PROGRAM - There is provided a biological information measurement apparatus including a biological information acquisition unit configured to acquire at least first waveform information relating to a first waveform representing a beat of a measurement subject measured at a first measurement site, and as second waveform information relating to a second waveform representing the beat of the measurement subject measured at a second measurement site different from the first measurement site, information relating to a timing corresponding to a second feature which is a characteristic feature of the second waveform, and a pulse wave transit time calculation unit configured to, based on the first and second waveform information, calculate a pulse wave transit time, which is a difference between a timing corresponding to a first feature which is a characteristic feature of the first waveform and the timing corresponding to the second feature which is a characteristic feature of the second waveform. | 06-05-2014 |
| 20140163399 | METHOD AND APPARATUS FOR NON-INVASIVELY MEASURING HEMODYNAMIC PARAMETERS USING PARAMETRICS - An improved method and apparatus for non-invasively assessing one or more hemodynamic parameters associated with the circulatory system of a living organism. In one aspect, the invention comprises a method of measuring a hemodynamic parameter (e.g., arterial blood pressure) by applanating or compressing portions of tissue proximate to the blood vessel of concern until a desired condition is achieved, and then measuring the hemodynamic parameter. Such applanation effectively mitigates transfer and other losses created by the tissue proximate to the blood vessel, thereby facilitating accurate and robust tonometric measurement. An algorithm adapted to maintain optimal levels of applanation is also described. Methods and apparatus for scaling such hemodynamic parameter measurements based on subject physiology, and providing treatment to the subject based on the measured parameters, are also disclosed. | 06-12-2014 |
| 20140163400 | WIRELESS BLOOD PRESSURE MEASURING TECHNIQUES - According to certain inventive techniques, a blood pressure recording device includes at least one blood pressure sensor, a display configured to visually present received data, a wireless transceiver, a memory storing a reminder time, and a processor including a clock. The processor is configured to: receive blood pressure data from the at least one blood pressure sensor; process the blood pressure data to form a systolic reading and a diastolic reading; transmit the systolic reading and the diastolic reading to the display for visual presentation to a user; transmit the systolic reading and the diastolic reading to the wireless transceiver for wireless transmission; retrieve the reminder time from the memory; compare the reminder time to a time of the clock; and generate an alert when the clock time is equal to the reminder time. | 06-12-2014 |
| 20140171811 | PHYSIOLOGY MEASURING SYSTEM AND METHOD THEREOF - The current disclosure discloses a physiology measuring system comprising a sensing device and a signal processing device. The sensing device comprises a first antenna, a second antenna, a first pulse signal generator, a second pulse signal generator, a first pulse signal receiver, a second pulse signal receiver and a first wireless module. The signal processing device further comprises a second wireless module and a microcontroller having a calculation unit which has an algorithm. The first wireless module communicates with the second wireless module via a wireless protocol. | 06-19-2014 |
| 20140171812 | DEVICES, SYSTEMS AND METHODS FOR THE DETECTION OF CORONARY ARTERY DISEASE - Embodiments relate to non-invasive medical devices, systems and methods for the detection of coronary artery disease. In an embodiment, a handheld coronary artery disease (CAD) detection device is used in a non-invasive manner to determine whether an internal coronary artery blockage is present. The CAD detection device can be used in conjunction with an identification element, such as scanning area identification pads or a scanning area guide, to aid in the proper placement of the CAD detection device while scanning a patient. Advantages of embodiments include non-invasive test procedures; quick results; and cost-effectiveness. | 06-19-2014 |
| 20140187977 | METHOD AND AN APPARATUS FOR DETERMINATION OF BLOOD PRESSURE - A method and an apparatus for non-interfering blood pressure measurements, relates to an apparatus for continuously monitoring blood pressure for patients at home or at work. The apparatus includes an extra-corporal sensor for blood pressure determination with a flexible housing adapted to be attached to the body of a living being proximate to an artery, and an electronic circuit for wireless coupling to a remote transceiver in accordance with the blood pressure in the artery, the remote transceiver adapted for wireless coupling to the sensor for generation of a pressure signal in accordance with the blood pressure in the artery, and a processor connected to the remote transceiver for reception of the pressure signal and adapted to estimate systolic and diastolic pressure based on the signal. | 07-03-2014 |
| 20140200464 | PATIENT TEMPERATURE CHANGE COMBINED WITH REMOTE ISCHEMIC CONDITIONING - A single system may provide to a patient: temperature change, remote ischemic conditioning, and sometimes both concurrently. The system may include a patient unit that includes an inflatable bladder, and a duct having a cavity. The patient unit is intended to be applied around a patient's limb. A temperature subsystem can force a flow of a first fluid through the cavity so that the first fluid can exchange heat with the patient's limb. The pressure subsystem may force a fluid into the bladder, to establish pressure against the limb. A controller may control both the temperature subsystem and the pressure subsystem, so as to control the treatment received by the patient. | 07-17-2014 |
| 20140207005 | SYSTEM AND METHOD FOR REAL-TIME THREE DIMENSIONAL MODELING OF CARDIOVASCULAR DYNAMICS AND THE HEART USING ELECTROCARDIOGRAM SIGNALS - There is taught herein a real-time, lumped parameter cardiovascular dynamics model that uses features extracted from online electrocardiogram (ECG) signal recordings to generate certain surrogate hemodynamic signals. The derived signals can be used to real time animate a 3-D heart model. The model represents the coupled dynamics of the heart chambers, valves, and pulmonary and systemic blood circulation loops in the form of nonlinear differential equations. The features extracted from ECG signals can be used to estimate the timings and amplitudes of the atrioventricular activation input functions as well as other model parameters that capture the effect of cardiac morphological and physiological characteristics. The results indicate the potential of a virtual instrument that uses the model-derived signals for clinical diagnosis in lieu of expensive instrumentation. | 07-24-2014 |
| 20140207006 | STRAIN SENSOR ELEMENT AND BLOOD PRESSURE SENSOR - A strain sensor element comprises a laminated film which has a magnetic free layer, a spacer layer, and a magnetic reference layer. The free layer has a variable magnetization direction and a out-of-plane magnetization direction. The reference layer has a variable magnetization direction which is pinned more strongly than the magnetization of the free layer. The spacer layer provided between the free layer and the reference layer. A pair of electrodes is provided with a plane of the laminated film. A substrate is provided with either of the pair electrodes and can be strained. The rotation angle of the magnetization of the free layer is different from the rotation angle of the magnetization of the reference layer when the substrate is distorted. Electrical resistance is changed depending on the magnetization angle between the free layer and the reference layer, which allows the element to operate as a strain sensor. | 07-24-2014 |
| 20140207007 | STRAIN SENSOR ELEMENT AND BLOOD PRESSURE SENSOR - A strain sensor element comprises a laminated film which has a magnetic free layer, a spacer layer, and a magnetic reference layer. The free layer has a variable magnetization direction and a out-of-plane magnetization direction. The reference layer has a variable magnetization direction which is pinned more strongly than the magnetization of the free layer. The spacer layer provided between the free layer and the reference layer. A pair of electrodes is provided with a plane of the laminated film. A substrate is provided with either of the pair electrodes and can be strained. The rotation angle of the magnetization of the free layer is different from the rotation angle of the magnetization of the reference layer when the substrate is distorted. Electrical resistance is changed depending on the magnetization angle between the free layer and the reference layer, which allows the element to operate as a strain sensor. | 07-24-2014 |
| 20140213914 | ARTERIAL PRESSURE-BASED, AUTOMATIC DETERMINATION OF A CARDIOVASCULAR PARAMETER - One or more cardiovascular parameters is estimated as a function of the arterial pressure waveform, in particular, using at least one statistical moment of a discrete representation pressure waveform having an order greater than one. Arterial compliance, the exponential pressure decay constant, vascular resistance, cardiac output, and stroke volume are examples of cardiovascular parameters that can be estimated using various aspects of the invention. In one embodiment of the invention, not only are the first four moments (mean, standard deviation, skewness, and kurtosis) of the pressure waveform used to estimate the cardiovascular parameter(s) of interest, but also heart rate, statistical moments of a set of pressure-weighted time values, and certain anthropometric patient measurements such as age, sex, body surface area, etc. | 07-31-2014 |
| 20140236028 | BLOOD-PRESSURE SENSOR - A blood-pressure sensor includes a substrate, a first electrode, a magnetization fixed layer, a nonmagnetic layer, a magnetization free layer, and a second electrode. The substrate is bent to generate a tensile stress at least in a first direction. The first electrode is provided on the substrate. The magnetization fixed layer has magnetization to be fixed in a second direction, and is provided on the substrate. The nonmagnetic layer is provided on the magnetization fixed layer. The magnetization free layer has a magnetization direction which is different from the first direction and from a direction perpendicular to the first direction. The second electrode is provided on the magnetization free layer. | 08-21-2014 |
| 20140249431 | BODY-WORN SYSTEM FOR CONTINUOUS, NONINVASIVE MEASUREMENT OF CARDIAC OUTPUT, STROKE VOLUME, CARDIAC POWER, AND BLOOD PRESSURE - The invention provides a system for measuring stroke volume (SV), cardiac output (CO), and cardiac power (CP) from a patient that features: 1) an impedance sensor connected to at least two body-worn electrodes and including an impedance circuit that processes analog signals from the electrodes to measure an impedance signal (e.g. TBEV waveform); 2) an ECG sensor connected to at least two chest-worn electrodes and including an ECG circuit that processes analog signals from the electrodes to measure and ECG signal; 3) an optical sensor connected to a body-worn optical probe and including an optical circuit that processes signals from the probe to measure at least one optical signal (e.g. a PPG waveform) from the patient; 4) a processing system, typically worn on the patient's wrist and connected through a wired interface to the optical sensor, and through either a wired or wireless interface to the TBEV and ECG sensors. | 09-04-2014 |
| 20140249432 | BODY-WORN SYSTEM FOR CONTINUOUS, NONINVASIVE MEASUREMENT OF CARDIAC OUTPUT, STROKE VOLUME, CARDIAC POWER, AND BLOOD PRESSURE - The invention provides a system for measuring stroke volume (SV), cardiac output (CO), and cardiac power (CP) from a patient that features: 1) impedance sensor connected to at least two body-worn electrodes and including an impedance circuit that processes analog signals from the electrodes to measure an impedance signal (e.g. a TBEV waveform); 2) an ECG sensor connected to at least two chest-worn electrodes and including an ECG circuit that processes analog signals from the electrodes to measure and ECG signal; 3) an optical sensor connected to a body-worn optical probe and including an optical circuit that processes signals from the probe to measure at least one optical signal (e.g. a PPG waveform) from the patient; 4) a processing system, typically worn on the patient's wrist and connected through a wired interface to the optical sensor, and through either a wired or wireless interface to the TBEV and ECG sensors. | 09-04-2014 |
| 20140249433 | BODY-WORN SYSTEM FOR CONTINUOUS, NONINVASIVE MEASUREMENT OF CARDIAC OUTPUT, STROKE VOLUME, CARDIAC POWER, AND BLOOD PRESSURE - The invention provides a system for measuring stroke volume (SV), cardiac output (CO), and cardiac power (CP) from a patient that features: 1) impedance sensor connected to at least two body-worn electrodes and including an impedance circuit that processes analog signals from the electrodes to measure an impedance signal (e.g. a TBEV waveform); 2) an ECG sensor connected to at least two chest-worn electrodes and including an ECG circuit that processes analog signals from the electrodes to measure and ECG signal; 3) an optical sensor connected to a body-worn optical probe and including an optical circuit that processes signals from the probe to measure at least one optical signal (e.g. a PPG waveform) from the patient; 4) a processing system, typically worn on the patient's wrist and connected through a wired interface to the optical sensor, and through either a wired or wireless interface to the TBEV and ECG sensors. | 09-04-2014 |
| 20140249434 | BODY-WORN SYSTEM FOR CONTINUOUS, NONINVASIVE MEASUREMENT OF CARDIAC OUTPUT, STROKE VOLUME, CARDIAC POWER, AND BLOOD PRESSURE - The invention provides a system for measuring stroke volume (SV), cardiac output (CO), and cardiac power (CP) from a patient that features: 1) an impedance sensor connected to at least two body-worn electrodes and including an impedance circuit that processes analog signals from the electrodes to measure an impedance signal (e.g. TBEV waveform); 2) an ECG sensor connected to at least two chest-worn electrodes and including an ECG circuit that processes analog signals from the electrodes to measure and ECG signal; 3) an optical sensor connected to a body-worn optical probe and including an optical circuit that processes signals from the probe to measure at least one optical signal (e.g. a PPG waveform) from the patient; 4) a processing system, typically worn on the patient's wrist and connected through a wired interface to the optical sensor, and through either a wired or wireless interface to the TBEV and ECG sensors. | 09-04-2014 |
| 20140276134 | NON-INVASIVE METHOD AND DEVICE OF MEASURING THE REAL-TIME CONTINUOUS PRESSURE OF FLUID IN ELASTIC TUBE AND THE DYNAMIC COMPLIANCE OF ELASTIC TUBE - The invention presents a non-invasive method and device of measuring the real-time continuous pressure of fluid fluctuating in an elastic tube and the dynamic compliance of the elastic tube, in which the theory of VLDT (Vascular Loading Decoupling Technique) is used. After searching the initial critical depth and determining the decoupled ratio, a DC controller generates a DC control gain to maintain the elastic tube at critical depth, and an AC controller employs the self-adaptive and Step-Hold control rules to create the pulsation of elastic tube without effect of surrounding tissues, and be capable of measuring the real-time continuous fluid pressure and dynamic compliance of elastic tube. | 09-18-2014 |
| 20140276135 | DEVICES, METHODS AND KITS FOR DELIVERY OF THERAPEUTIC MATERIALS TO A PANCREAS - An apparatus includes an inner catheter that is coupled to a handle and defines a lumen configured to receive a guidewire. An outer catheter is movably coupled to the handle and defines a first lumen in fluid communication with a distal opening and that is configured to introduce a therapeutic agent through the distal opening and into a target pancreatic artery(ies). The outer catheter defines a second lumen configured to receive at least a portion of the inner catheter. An actuator is coupled to the handle and configured to move the outer catheter relative to the handle. A first occlusion element is coupled to the inner catheter and a second occlusion element is coupled to the outer catheter and disposed proximal to the first occlusion element. A distance between the first occlusion element and the second occlusion element is adjustable when the outer catheter is moved relative to the handle. | 09-18-2014 |
| 20140288443 | MONITORING SYSTEM - A device, system and method for monitoring blood pressure information of a user. A device is configured with first and second pressure sensors, a fastening element, and a processing component. In the method the first pressure sensor is detachably attached to a first position and the second pressure sensor to a second position on the outer surface of a skin of the user. The pressure sensor generate signals that vary according to deformations of the skin in response to an arterial pressure wave expanding or contracting a blood vessel underlying the skin. The first signal and the second signal are used to compute at least one output value that represents a detected characteristic of the progressing arterial pressure wave of the user. | 09-25-2014 |
| 20140303509 | METHOD AND APPARATUS FOR NON-INVASIVE DETERMINATION OF CARDIAC OUTPUT - A non-invasive method and apparatus determines continuously cardiac output by first analysing the trace obtained from an optical sensor which has been scaled and calibrated using an electronic sphygmomanometer. From this the mean arterial pressure and time constant are determined. Compliance is determined from the pulse delay between two other optical sensors at well separated sites. Cardiac output is the product of mean arterial pressure and compliance divided by the time constant. A microcomputer provides the necessary calculations. | 10-09-2014 |
| 20140309541 | BLOOD PRESSURE MEASUREMENT DEVICE AND CONTROL METHOD FOR BLOOD PRESSURE MEASUREMENT DEVICE - A blood pressure measurement device determines an amplitude and a frequency of a voltage applied to a piezoelectric pump, carries out control so that a voltage at the determined amplitude and frequency is applied to the piezoelectric pump, and calculates a blood pressure value based on a detected cuff pressure during inflation when the cuff pressure is increased by the piezoelectric pump. A control frequency at which a pump efficiency of the piezoelectric pump is maximum in the case where the fluid is supplied to the cuff at a required flow rate during inflation using a predetermined voltage as the voltage is determined, and first control that applies a voltage at the amplitude of the predetermined voltage and at the determined control frequency is carried out. The amount of power consumed can be reduced when increasing the cuff pressure for blood pressure measurement using the piezoelectric pump. | 10-16-2014 |
| 20140316287 | System and method for displaying fluid responsivenss predictors - Embodiments provide systems and methods for displaying a fluid responsiveness predictor (FRP) based on an analysis a physiological signal detected by a physiological sensor applied to a patient. A method may include detecting the signal of the patient with the physiological sensor, determining an FRP with a FRP determination module, wherein the determining operation comprises analyzing at least one characteristic of the physiological signal over time to determine the FRP, receiving a report request to report the FRP at a requested time through a user interface, generating a reported FRP in relation to the requested time using the FRP determination module, and displaying the reported FRP on a display. The displaying operation may include displaying the FRP using at least one graphic representation. | 10-23-2014 |
| 20140316288 | Method and Apparatus for Measuring Blood Pressure - Embodiments of the present invention provide an improved transformation method whereby the peripheral pulse waveform is filtered to separate different phases which make up the waveform. The separate phases are transformed before being re-combined to provide an estimated intra-arterial transfer function. For example, in one embodiment the peripheral pulse waveform is filtered by a first high pass filter, and a copy of the peripheral pulse waveform filtered by a second high pass filter, having a different cut-off frequency. The two filtered waveforms may then be further processed, for example by being added back to original wave-form, and are then multiplexed together in a time division manner to provide a final waveform. For example, the part of the first filtered waveform corresponding to the systolic phase may be combined with the part of the second filtered waveform corresponding to the diastolic phase to produce the final waveform, and the respective filter cut-off frequencies may be chosen to extract characteristics of the respective phases of the heart. | 10-23-2014 |
| 20140323885 | METHODS AND SYSTEMS FOR PREDICTING ACUTE HYPOTENSIVE EPISODES - A method is presented. The method includes determining a plurality of temporal training features corresponding to one or more hemodynamic parameters of a plurality of elected-patients based upon temporal training signals representative of the one or more hemodynamic parameters, and generating an acute hypotension prediction classifier based upon the plurality of temporal training features corresponding to the one or more hemodynamic parameters of the plurality of elected-patients, wherein the plurality of temporal training features comprises covariance between two or more of the temporal training signals corresponding to the one or more hemodynamic parameters. | 10-30-2014 |
| 20140343441 | BLOOD PRESSURE DIAGNOSTIC DEVICE PROVIDING ENHANCED VASCULAR CONDITION DETECTION FEATURES AND RELATED METHODS - A medical diagnostic system may include a plurality of blood pressure measuring devices each configured to measure blood pressure of a respective extremity from among a plurality of extremities of a patient, and a blood pressure diagnostic device including at least one input device and a controller. The controller may cooperate with the at least one input device to determine blood pressure measurements for the respective patient extremities based upon the plurality of blood pressure measuring devices, receive an indicator of at least one symptom of the patient via the input device, and determine statistical probabilities that a condition of the patient is within a first group of vascular conditions requiring a first course of treatment, and a second group of vascular conditions requiring a second course of treatment different than the first course of treatment, based upon the determined blood pressure measurements and the indicator of the at least one symptom. | 11-20-2014 |
| 20140350416 | CABLES FOR PATIENT MONITORING AND RELATED SYSTEMS WITH INTEGRATED FRONT END - Patient monitoring systems can include a system for transmitting information from a patient parameter sensor to a patient monitor. The system can include an analogue-to-digital converter close to the patient parameter sensor and can transmit digital signals through a cable to the patient monitor. | 11-27-2014 |
| 20140358015 | METHOD FOR ESTIMATING CHANGES OF CARDIOVASCULAR INDICES USING PERIPHEAL ARTERIAL BLOOD PRESSURE WAVEFORM - The systems and methods described herein enable reliable estimation of cardiovascular indices on real-time, non-invasive or minimally-invasive, and heat-to-beat basis. Cardiovascular indices which can be estimated include: stroke volume (SV), which being limited to, cardiac output (CO) and total peripheral resistance (TPR). In various embodiments, one or more of these indices are estimated continuously, on a beat-to-beat basis, using peripheral arterial blood pressure (ABP) waveforms and certain parameters derived from the peripheral ABP waveforms. The derived parameters are substantially insensitive to distortions of the ABP waveform arising from tapered arterial branches throughout the arterial tree. The methods describe herein can provide a more accurate and reliable estimate of hemodynarnic parameters than existing techniques. | 12-04-2014 |
| 20150025396 | BLOOD PRESSURE ANALYSIS SYSTEM AND METHOD - A blood pressure analysis system/method allowing conversion from an analog sensor input to a standardized analog output interface is disclosed. In some preferred embodiments the system/method permits a fiber optic pressure sensor to be interfaced to a standard patient care monitor (PCM) system using standardized Wheatstone Bridge analog interface inputs. Within this context the Wheatstone Bridge sensed output is defined by stimulus from the PCM and modulation of bridge element values by the conditioned output of an analog pressure sensor. The use of analog-to-digital-to-analog conversion in this blood pressure analysis permits retrofitting of PCM devices having analog Wheatstone Bridge inputs with advanced patient monitoring sensors without the need for specialized modifications to the baseline PCM data collection framework. Methods disclosed herein include techniques to connect arbitrary types/numbers of analog sensors to traditional PCM systems without the need for PCM system hardware/software modifications. | 01-22-2015 |
| 20150038857 | BLOOD PRESSURE-RELATED INFORMATION DISPLAY DEVICE - A blood pressure-related information display device according to a preferred embodiment of the present invention displays, in a part of a display screen, a blood pressure evaluation item list display field indicating a plurality of types of blood pressure evaluation items and a quality display field indicating a quality of each of the blood pressure evaluation items as images. The blood pressure evaluation item list display field includes a header area and a body area. The blood pressure evaluation items are displayed in the body area in list format so all of the items can be viewed, and so that any one of the plurality of types of blood pressure evaluation items can be selected. Icon marks that indicate the quality of the blood pressure evaluation results are displayed in the quality display field, provided on the left side of the body area and arranged to the left of the corresponding blood pressure evaluation items. | 02-05-2015 |
| 20150045680 | BLOOD-PRESSURE RELATED INFORMATION DISPLAY DEVICE - A blood pressure-related information display device displays a representative value setting field for setting a representative value obtainment mode as an image in a part of a display screen. The representative value setting field includes a setting area and a list area, the latter of which is displayed when, for example, a doctor clicks an inverted triangular mark in the setting area with a mouse. Representative value obtainment modes are displayed in the list area in list format so that all the modes can be viewed. The list area is configured so that any one of a plurality of types of representative value obtainment modes can be selected. | 02-12-2015 |
| 20150057554 | SYSTEMS AND METHODS FOR MONITORING BLOOD PRESSURE - Various methods and systems for blood pressure monitoring are provided. A device for monitoring blood pressure may include a memory storing instructions for receiving one or more signals representative of one or more patient parameters, wherein at least one of the one or more signals comprises a plethysmography signal. The memory also stores instructions for determining a change in a pulse shape metric of the plethysmography signal and determining a change in a blood pressure signal over a period of time based on the one or more signals. The memory also stores instructions for determining a confidence level of the blood pressure signal based at least in part on a correlation between the change in the blood pressure signal and the change in the pulse shape metric over the period of time. The device also includes a processor configured to execute the instructions. | 02-26-2015 |
| 20150080750 | Disposable Sensor Device and Monitoring System - The invention relates to a disposable sensor device ( | 03-19-2015 |
| 20150088008 | PRESSURE SENSOR, MICROPHONE, BLOOD PRESSURE SENSOR, AND TOUCH PANEL - According to one embodiment, a pressure sensor includes a support, a film unit supported by the support, having an upper surface, and capable of being deformed, and a first sensing element provided on the upper surface. The first sensing element includes a first magnetic layer, a second magnetic layer provided apart from the first magnetic layer and a first intermediate unit including a first intermediate layer including a portion provided between the first and second magnetic layers. The first magnetic layer extends in a first direction parallel to the upper surface, and a first major axis length of the first magnetic layer is longer than a first minor axis length. The second magnetic layer extends in a second direction parallel to the upper surface and crossing the first direction, and a second major axis length of the second magnetic layer is longer than a second minor axis length. | 03-26-2015 |
| 20150094601 | MEDICAL DEVICE INCLUDING SETUP OPTION REPORTING - A medical device for use with a patient is described. The medical device includes a component for administering a treatment to the patient or receiving data of the patient. The component is configured to operate according to an internal setting. The medical device also includes a user interface through which a user can modify the internal setting, as well as a settings signature generator for generating a settings signature that represents a present state of the internal setting. A gateway is also provided for communicating a version of the settings signature out of the medical device. | 04-02-2015 |
| 20150133798 | METHODS FOR NONINVASIVE INTRACRANIAL PRESSURE CALIBRATION WITHOUT THE NEED FOR INVASIVE ICP - Systems and methods for assessing a non-accessible parameter from accessible parameters are provided. A training process produces three databases: A dynamical model database containing input/output (I/O) models relating ABP/CBFV to ICP when estimating ICP; a mapping function database containing a mapping function for each entry in the model database, providing estimated of the dissimilarity between the unknown ICP and simulated ICP using the corresponding dynamical model on a given instance of ABP/CBFV; and a query feature database of vectors extracted from an instance of ABP/CBFV. New ABP/CBFV measurements are analyzed to extract query features that are evaluated by each mapping function in the database. The output is dissimilarity metrics providing estimates of the quality of the simulated ICP using the database models for a given ABP/CBFV instance. The dissimilarity metrics are ranked to find the optimal model. The model is used to simulate ICP using the new ABP/CBFV. | 05-14-2015 |
| 20150327784 | Non-Interfering Blood Pressure Measuring - Systems, methods, and devices of various embodiments enable measurement of blood pressure from an artery. The various embodiments may measure, using a non-interfering arterial measurement sensor, a first change in distension of the artery at a measurement location without interference to an arterial pressure at the measurement location during a series of pulses. A first pulse rate and estimated pulse pressures may be determined from the first change in distension. A coefficient may be determined fitting an exponentially decaying function representing an exponential decay of a portion of a diastolic phase to select ones of the estimated pulse pressures corresponding to the diastolic phase. An absolute blood pressure may be determined by applying the coefficient to a select mathematical model expressing a first relationship between the first change in distension of the artery and the pulse pressure in the artery at the measurement location. | 11-19-2015 |
| 20150338292 | STRAIN SENSOR ELEMENT AND BLOOD PRESSURE SENSOR - A strain sensor element comprises a laminated film which has a magnetic free layer, a spacer layer, and a magnetic reference layer. The free layer has a variable magnetization direction and a out-of-plane magnetization direction. The reference layer has a variable magnetization direction which is pinned more strongly than the magnetization of the free layer. The spacer layer provided between the free layer and the reference layer. A pair of electrodes is provided with a plane of the laminated film. A substrate is provided with either of the pair electrodes and can be strained. The rotation angle of the magnetization of the free layer is different from the rotation angle of the magnetization of the reference layer when the substrate is distorted. Electrical resistance is changed depending on the magnetization angle between the free layer and the reference layer, which allows the element to operate as a strain sensor. | 11-26-2015 |
| 20150351695 | MEDICAL SMARTPHONE - Methods and systems are presented for analyzing physiological data at an operating system of a user device in order to identify emergencies or medically significant events in real-time. In some embodiments, physiological data from a wearable physiological monitoring device may be analyzed in real-time on a user device (e.g., smartphone). In some embodiments, local and remote analyses of motion activity data feeds from data sources may be used to identify medically significant events in real-time. | 12-10-2015 |
| 20150351698 | HEALTH AND MEDICAL SMARTPHONE - Methods and systems are presented for analyzing physiological data and health data at an operating system of a user device in order to identify emergencies or medically significant events in real-time. In some embodiments, physiological parameter data and health parameter data retrieved from wearable monitors may be analyzed in real-time on a user device (e.g., smartphone). In some embodiments, notifications may be generated based on the analysis of the retrieved data. | 12-10-2015 |
| 20150359444 | BIOLOGICAL INFORMATION MEASURING APPARATUS AND BLOOD PRESSURE ANALYZING METHOD - A biological information measuring apparatus includes a blood pressure pulse wave measuring unit configured to measure a blood pressure pulse wave of a subject, a unit pulse wave producing unit configured to produce unit pulse waves of a certain unit from the blood pressure pulse wave based on an analysis of heart beats of the subject, a unit pulse wave extracting unit configured to analyze the unit pulse waves produced by the unit pulse wave producing unit and to extract only necessary unit pulse waves in accordance with the analysis, and an output unit configured to perform an output based on the unit pulse waves extracted by the unit pulse wave extracting unit. | 12-17-2015 |
| 20150366464 | METHOD AND DEVICE FOR TONOMETRIC BLOOD PRESSURE MEASUREMENT - A method for determining an artery location on a living subject's skin and positioning a tonometry pressure sensor on the artery location for tonometric blood pressure measurement is provided. The method comprises a non-contact optical search followed by a contact pressure search. In the non-contact optical search, an optical-sensing unit is used to scan the skin along a scan path while maintaining a pre-determined distance between the unit and the scan path. A search region within the scan path and a height profile characterizing the scan path's curvature are determined. The search region is determined such that an artery is predicted to lie thereunder. The artery location is then searched within the search region by the contact pressure search, in which the pressure sensor sweeps along the search region and the sweeping is guided by curvature information provided by the height profile. A device using the method is also provided. | 12-24-2015 |
| 20150366465 | BARORECEPTOR MAPPING SYSTEM - A system for mapping and marking baroreceptors of a patient. The system includes a mapping device, a marker, and a stimulator. The mapping device includes a plurality of electrodes to be situated on the patient. The marker is to be attached to the patient and mark a location of at least one of the plurality of electrodes based on an analysis of patient physiological responses to stimulation of the plurality of electrodes. The stimulator is to divide the plurality of electrodes into a first electrode zone and a second electrode zone and stimulate electrodes in the first electrode zone and the second electrode zone to obtain first patient physiological responses, where one of the first electrode zone and the second electrode zone is selected based on the first patient physiological responses. | 12-24-2015 |
| 20150374244 | APPARATUS FOR CONTINUOUSLY AND AUTOMATICALLY MEASURING PULSE WAVE AND METHOD FOR MEASURING BLOOD PRESSURE - Disclosed is an apparatus for continuously and automatically measuring a pulse wave by a non-invasive method to know the state of a cardiovascular system. The apparatus includes an integrated measurement module, a communication power module, and a bio-measurement pad. The integrated measurement module includes an electrocardiogram measurement portion for measuring the electrocardiogram of a subject, a bioelectrical impedance measurement portion for measuring the bioelectrical impedance of the subject by a potential difference, a heart sound measurement portion for measuring the heart sound of the subject, and a controller for measuring and controlling the state of the cardiovascular system of the subject on the basis of a pulse transit time calculated by the electrocardiogram signal measured at the electrocardiogram measurement portion, the bioelectrical impedance signal measured at the bioelectrical impedance measurement portion, and the heart sound signal measured at the heart sound measurement portion. | 12-31-2015 |
| 20160022152 | METHOD AND SYSTEM FOR MONITORING STRESS - Method and system for monitoring stress level of a subject. Beat-to-beat time variation and stroke volume variation of the heart a subject are obtained simultaneously, and a stress level indication is determined as a function of the beat-to-beat time variation and the relative stroke volume variation. More accurate and reliable estimates for stress level may be obtained. | 01-28-2016 |
| 20160045117 | Peak Detection System and Method for Calculation of Signal-Derived Metrics - The invention in at least one embodiment includes a method for providing a beat determination based on signals from a plurality of medical sensors in substantially real time, said method including: receiving in at least two analysis modules at least one signal (including an ECG signal and/or a pulse signal) from at least one medical sensor such that at least one analysis module receives one ECG signal and at least one analysis module receives one pulse signal; in each analysis module processing one signal through a plurality of detection algorithm modules to produce at least one quantitative decision, fusing the quantitative decisions together with a fusion module, and outputting at least one detected peak from the fusion module to an aggregation module; and producing from the aggregation module a series of detected peaks based on detected peaks received from the analysis modules. In a further embodiment, the detected peaks produced by the aggregation module are used to determine heart rate variability/complexity. At least one embodiment includes a system for performing any of the above methods. | 02-18-2016 |
| 20160045119 | External Calibration and Recalibration for a Blood Pressure Monitor - A method and system for the external calibration and recalibration of a blood pressure monitor comprising a continuous pulse waveform detector, a pulse decomposition analyzer for analyzing high resolution pulse wave forms, and an absolute blood pressure monitor. Upon startup, the pulse waveform detector is initialized by the pulse decomposition analyzer based upon a reading from the absolute blood pressure monitor. Upon detection of a physiological event from the pulse decomposition analyzer, the absolute blood pressure monitor is directed to take a reading which is then used to recalibrate the pulse waveform detector. | 02-18-2016 |
| 20160051150 | METHOD AND APPARATUS FOR MEASURING BLOOD PRESSURE USING AN ACOUSTIC SIGNAL - There is provided a method for measuring the blood pressure of a subject, comprising receiving an acoustic signal comprising an electronic representation of sounds generated by a hemodynamic effect of the subject's heart beats on one or more blood vessels in a body part of a subject; deriving one or more parameters from the received acoustic signal; and calculating a blood pressure value based on the one or more derived parameters. | 02-25-2016 |
| 20160058385 | DEVICE, DEVICE CONTROL METHOD AND CONTROL PROGRAM, AND SYSTEM - Provided is a device which can utilize a motion sensor installed in a mobile device. A smartphone includes a motion sensor and a controller. The motion sensor detects a motion factor. The controller processes the motion factor detected by the motion sensor as a self-control factor. The controller can process the motion factor detected by the motion sensor as a vital-sign factor of a user. | 03-03-2016 |
| 20160066861 | METHOD AND SYSTEM FOR QUANTIFYING LIMITATIONS IN CORONARY ARTERY BLOOD FLOW DURING PHYSICAL ACTIVITY IN PATIENTS WITH CORONARY ARTERY DISEASE - Embodiments include a system for determining cardiovascular information for a patient with coronary artery disease. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of the patient's heart and create a model representing at least a portion of the patient's heart based on the patient-specific data. The at least one computer system may be further configured to create, for a given level of physical activity, a physics-based model of blood flow through the patient's heart simulated during a selected level of physical activity; determine and normalize one or more values of at least one blood flow characteristic within the patient's heart during the simulated level of physical activity; and compare the one or more normalized values of the at least one blood flow characteristic to a threshold to determine whether the level of physical activity exceeds an acceptable level of risk. | 03-10-2016 |
| 20160066862 | METHOD AND SYSTEM FOR QUANTIFYING LIMITATIONS IN CORONARY ARTERY BLOOD FLOW DURING PHYSICAL ACTIVITY IN PATIENTS WITH CORONARY ARTERY DISEASE - Embodiments include a system for determining cardiovascular information for a patient with coronary artery disease. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of the patient's heart and create a model representing at least a portion of the patient's heart based on the patient-specific data. The at least one computer system may be further configured to create, for a given level of physical activity, a physics-based model of blood flow through the patient's heart simulated during a selected level of physical activity; determine and normalize one or more values of at least one blood flow characteristic within the patient's heart during the simulated level of physical activity; and compare the one or more normalized values of the at least one blood flow characteristic to a threshold to determine whether the level of physical activity exceeds an acceptable level of risk. | 03-10-2016 |
| 20160073883 | DEVICE AND METHOD FOR ACQUIRING BIOLOGICAL INFORMATION BY MEANS OF AN INTRACORPOREAL CURRENT - A receiving device with intracorporeal current having a device for collecting, by capacitive coupling, an AC signal depending on a current that has passed through all or part of the body of a subject, a device for extracting data from the AC signal collected, and a device for extracting from the AC signal a biological signal generated by the body of the subject and modulating the amplitude of the AC signal. | 03-17-2016 |
| 20160081563 | SYSTEMS AND METHODS TO ESTIMATE OR MEASURE HEMODYNAMIC OUTPUT AND/OR RELATED CARDIAC OUTPUT - Certain aspects of the instant disclosure are sensing and/or providing estimates for blood pressure or cardiac output by using time-synchronous communication (or correlation) between two sensors. Specific embodiments concern an arrangement of devices including a time-synchronous circuit and a sensor. The sensor is configured to obtain, at or near a lower-body/extremity location of the user, time-related data indicative of speed or transit time of a propagating pressure wave while the wave travels in an artery and down a leg of the user. The time-synchronous circuit is configured to correlate information corresponding to or derived from the time-related data in a time synchronous manner with other cardiovascular information. The cardiovascular information corresponds to or is derived from hemodynamic output from the user by another sensor located at or near an upper-extremity location or lower-extremity of the user. | 03-24-2016 |
| 20160095557 | Blood Pressure Monitor Calibration - A blood pressure monitor, particularly of the type having an inflatable cuff communicating with a pressure sensor and suitable for home use, may be calibrated by applying a sealed canister containing gas at a known pressure to a port so as to apply the known pressure to the pressure sensor, and comparing a pressure signal from the pressure sensor with the known pressure so as to determine a calibration error of the sensor and/or adjust the calibration of the sensor, e.g. by electronically adjusting the sensor. Several canisters may be used to calibrate the sensor across a range of pressures, each canister having a different known pressure. Each canister is preferably ruptured when attached to the port and is not re-usable, and may comprise an identifier such as an electronically readable identifier which is stored in a memory in association with the value of the known pressure within the canister. Temperature sensing means may be provided whereby the pressure reading is adjusted to compensate for temperature, e.g. of the gas released from the canister. The monitor may comprise means for sensing mechanical shock and alerting a user or remote monitoring personnel to provide an indication that recalibration is required. | 04-07-2016 |
| 20160110865 | SYSTEMS AND METHODS FOR ESTIMATING HEMODYNAMIC PARAMETERS FROM A PHYSIOLOGICAL CURVE IMAGE - Systems and methods for estimating hemodynamic parameters from physiological curve images. A mobile device captures pictures of a physiological monitor display, which are used to extract the relevant physiological curve and upload it to an analysis server for processing and estimation of hemodynamic parameters. In some examples, the mobile device runs a dedicated application and is Internet-connected, which in turn connects to an Internet-connected analysis server. In some further examples, the system can be implemented using any computer that is capable of taking an image, extracting a physiological curve, and uploading it to a network service for analysis. In still further examples, analysis can be performed by the mobile device instead of via a remote server. | 04-21-2016 |
| 20160113589 | BIOSIGNAL PROCESSING METHOD AND APPARATUS - Biosignal processing method and apparatus are provided. The biosignal processing method includes: detecting a biosignal, which is generated by a movement of a heart existing in a second area of a subject, from a first area of the subject; generating of a biosignal waveform from the biosignal; determining a relative position of the first area with respect to the second area based on at least one of the biosignal waveform and a direction of the first area; and converting the biosignal waveform to a reference biosignal waveform based on the relative position. | 04-28-2016 |
| 20160120419 | RADIAL ARTERY BLOOD PRESSURE WAVEFORM MEASURING DEVICE - A radial artery blood pressure waveform measuring device includes a stress sensor, a stress concentrating elastic structure, and a stress guiding elastic member. The stress sensor is in contact with a skin surface of a wrist corresponding to a position of a radial artery. The stress concentrating elastic structure is disposed on the stress sensor. The stress guiding elastic member has a top surface, a bottom surface, and at least one side surface. The bottom surface is disposed on the stress concentrating elastic structure, and an area of the bottom surface is greater than an area of a horizontal section of the stress concentrating elastic structure. | 05-05-2016 |
| 20160143543 | Patient Signal Filtering - Disclosed herein is a framework for facilitating patient signal filtering. In accordance with one aspect, the framework performs a signature cycle matching pursuit method to remove a first signal component from a combination patient signal and generate a first output signal. Sub-bandwidth filtering of the first output signal may be performed to remove a second signal component and generate a second output signal. The framework may further remove a third signal component from the second output signal to generate a third output signal. A signal of interest may then be reconstructed based on the third output signal. | 05-26-2016 |
| 20160150979 | METHOD AND DEVICE FOR MONITORING AND IMPROVING ARTERIOGENESIS | 06-02-2016 |
| 20160150983 | METHODS FOR MEASURING BLOOD PRESSURE | 06-02-2016 |
| 20160198953 | MEDICAL SCREENING DEVICE | 07-14-2016 |
| 20160203285 | MEDICAL SCREENING DEVICE | 07-14-2016 |
| 20170231496 | WIRELESS BLOOD PRESSURE MEASURING TECHNIQUES | 08-17-2017 |
| 20170231562 | METHOD AND APPARATUS FOR ASSESSING DEGREE OF ALIGNMENT BETWEEN LIFE ACTIVITY RHYTHM AND CIRCADIAN RHYTHM | 08-17-2017 |
| 20180020975 | ELECTRODE FOR A USER WEARABLE APPARATUS | 01-25-2018 |
| 20180020989 | MEAN ARTERIAL PRESSURE (MAP) DERIVED PREDICTION OF FUTURE HYPOTENSION | 01-25-2018 |
| 20190142346 | Method of Blood Pressure Estimation Using Trend Analysis | 05-16-2019 |
| 20220133163 | BLOOD PRESSURE MEASUREMENT DEVICE - A device for measuring blood pressure can include a housing including a groove to receive a finger of a user. The groove can have a curved end towards a center of the housing and can have a first dimension between 20 mm and 70 mm, a second dimension between 20 mm and 35 mm, and a third dimension between 3 mm and 10 mm. The device can include a light source disposed within the housing and positioned at a bottom region of the groove and configured to emit light in the groove. The device can include a photodetector disposed within the housing and positioned at the bottom region of the groove and configured to capture a sequence of image frames while the light is emitted. The device can include a processor configured to generate a photoplethysmographic (PPG) signal of a user using the sequence of image frames. | 05-05-2022 |
| 20220133241 | SYSTEMS AND METHODS FOR AUTOCORRELATION BASED ASSESSMENT OF PPG SIGNAL QUALITY - Systems and methods for assessing PPG signals generated based on transdermal optical data can include a computing device generating a color intensity signal using an acquired sequence of transdermal images of a subject. The computing device can compute a signal quality metric of the color intensity signal. The computing device can provide an indication of a quality of the color intensity signal for display on a display device associated with the computing device. The indication of the quality of the color intensity signal can be determined based on the signal quality metric. | 05-05-2022 |
