| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 600314000 | Foreign substance | 19 |
| 20090156914 | MEDICAL SENSOR AND TECHINIQUE FOR USING THE SAME - A sensor is provided that is appropriate for transcutaneous detection of tissue or blood constituents. A sensor for tissue constituent detection may include a gas collection chamber with a conduit to a sensing component and a conduit from the sensing component to the chamber. A sensor as provided may also include a barrier layer to prevent water from infiltrating the sensor. | 06-18-2009 |
| 20120143024 | Recombinant Bacteriophage for Detection of Nosocomial Infection - Disclosed herein are methods and devices for detection of bacterial HAI. Disclosed methods may be utilized for continuous in vivo monitoring of a potential bacterial infection site and may be utilized to alert patients and/or health care providers to the presence of pathogenic bacteria at an early stage of infection. Disclosed methods include utilization of recombinant bacteriophage to deliver to pathogenic bacteria a translatable genetic sequence encoding an optically detectable marker or an enzyme capable of producing an optically detectable marker. Upon detection of the optical signal produced by the marker, medical personnel may be alerted to the presence of pathogenic bacteria at the site of inquiry. Any bacterial causative agent of HAI may be detected according to disclosed methods. | 06-07-2012 |
| 20120197096 | System for Noninvasive Determination of Analytes in Tissue - An apparatus and method for noninvasive determination of analyte properties of human tissue by quantitative infrared spectroscopy to clinically relevant levels of precision and accuracy. The system includes subsystems optimized to contend with the complexities of the tissue spectrum, high signal-to-noise ratio and photometric accuracy requirements, tissue sampling errors, calibration maintenance problems, and calibration transfer problems. The subsystems can include an illumination/modulation subsystem, a tissue sampling subsystem, a data acquisition subsystem, a computing subsystem, and a calibration subsystem. The invention can provide analyte property determination and identity determination or verification from the same spectroscopic information, making unauthorized use or misleading results less likely than in systems that use separate analyte and identity determinations. The invention can be used to control and monitor individuals accessing controlled environments. | 08-02-2012 |
| 20120283529 | METHOD FOR DETECTING ANALYTE IN A BODILY FLUID, AND DRESSING FOR IMPLEMENTING SUCH A METHOD - A method for detecting an analyte in a bodily fluid includes placing the detector in contact with at least one metabolite resulting from the metabolism or degradation of the analyte. The contact between the detector and the metabolite produces an optically detectable signal. The detection method includes the detection of the metabolite only in gas form, said metabolite in gas form coming from the evaporation of at least a part of said metabolite. The detection is also carried out without contact between the bodily fluid and the detector. A dressing for implementing the detection method is also described. | 11-08-2012 |
| 20120330116 | System for Non-Invasive Assay of Liver Function - A system, method and apparatus are disclosed for using a transcutaneous detection system to measure the quantity of a circulating organ activity detection analyte in the blood, and thereby assay the activity of an organ. A preferred organ for assay is the human liver and a preferred indicator is indocyanine green (ICG) dye The procedure is under the control of a monitor/controller having a visual display and capable of providing cues to the operator. A sensor array apparatus for use in conjunction with the system monitor/controller is configured for increased sensitivity of assaying organ function. | 12-27-2012 |
| 20130006068 | METHOD AND APPARATUS FOR SCREENING DRUG OFFENDERS - A self-contained drug screening apparatus, comprising a breath inlet component for receiving an exhaled air flow of a person, the exhaled air flow including saliva, and a sensor for sensing a presence of a drug in the saliva, and identification module for detecting an identifying characteristic of the person. | 01-03-2013 |
| 20130102861 | MEDICAL APPARATUS, THERAPY APPARATUS, METHOD OF ESTIMATING OPTICAL PROBE, AND CALIBRATION METHOD - According to an embodiment of the present application, there is provided a medical apparatus, including: a light source unit configured to be capable of emitting light including at least natural emission light, the light being guided into an optical probe; a first detecting unit configured to detect an intensity of light exiting from the light source unit; and a calculation unit configured to calculate to approximate to a non-linear function based on an intensity of light detected by the first detecting unit for calibration of the optical probe. | 04-25-2013 |
| 20130109934 | Device for Passively Removing a Target Component from Blood or Lymph of a Vertebrate Subject | 05-02-2013 |
| 20130144137 | METHOD AND SYSTEM FOR NON-INVASIVELY MONITORING BIOLOGICAL OR BIOCHEMICAL PARAMETERS OF INDIVIDUAL - A system and method are presented for use in monitoring one or more conditions of a subject's body. The system includes a control unit which includes an input port for receiving image data, a memory utility, and a processor utility. The image data is indicative of data measured by a pixel detector array and is in the form of a sequence of speckle patterns generated by a portion of the subject's body in response to illumination thereof by coherent light according to a certain sampling time pattern. The memory utility stores one or more predetermined models, the model comprising data indicative of a relation between one or more measurable parameters and one or more conditions of the subject's body. The processor utility is configured and operable for processing the image data to determine one or more corresponding body conditions; and generating output data indicative of the corresponding body conditions. | 06-06-2013 |
| 20130172697 | CALCULATION APPARATUS AND CALCULATION METHOD - [Object] To provide a calculation apparatus and a calculation method capable of calculating pharmaceutical concentration in a tissue in real time. | 07-04-2013 |
| 20130197326 | Compositions And Methods For Measurement of Analytes - Disclosed herein are compositions comprising an oblong optode sensing agent. The oblong optode sensing agent comprises a core and a semipermeable membrane, wherein the core comprises one or more sensors configured to bind to an analyte. In addition, methods of making and detecting the oblong optode sensing agents are disclosed. | 08-01-2013 |
| 20130317328 | Methods and Apparatuses for Noninvasive Determination of in vivo Alcohol Concentration using Raman Spectroscopy - Methods and apparatuses for the determination of an attribute of the tissue of an individual use non-invasive Raman spectroscopy. For example, the alcohol concentration in the blood or tissue of an individual can be determined. A portion of the tissue is illuminated with light, which propagates into the tissue where it is Raman scattered. The Raman scattered light is detected and can be combined with a model relating Raman spectra to alcohol concentration to determine the alcohol concentration in the blood or tissue. Correction techniques can reduce determination errors due to detection of light other than that from Raman scattering from the alcohol in the tissue. Other biologic information can be used with the Raman spectral properties to aid in the determination of alcohol concentration, for example age, height, weight, medical history and his/her family, ethnicity, skin melanin content, or a combination thereof. The method and apparatus can be optimized to provide reproducible and uniform radiance of the tissue, low tissue sampling error, depth targeting of the tissue layers or sample locations that contain the attribute of interest, efficient collection of Raman spectra, optical throughput, photometric accuracy, large dynamic range, thermal stability, calibration maintenance, calibration transfer, built-in quality control, and ease-of-use. | 11-28-2013 |
| 20140058224 | SYSTEMS AND METHODS FOR DETECTION OF CAROTENOID-RELATED COMPOUNDS IN BIOLOGICAL TISSUE - A method for measuring and quantifying biological compounds is described. A first side of a sample is illuminated with a light source. Light transmitted from a second side of the sample is detected. The second side of the sample is opposite the first side of the sample. A result is obtained based on the detected light. | 02-27-2014 |
| 20140171762 | WEARABLE LIGHT-GUIDING BANDS AND PATCHES FOR PHYSIOLOGICAL MONITORING - A monitoring device includes a band capable of encircling a portion of the body of a subject, and an optical emitter and detector attached to the band. The band includes comprises light transmissive material in optical communication with the optical emitter and optical detector and is configured to deliver light from the optical emitter to one or more locations of the body of the subject and to collect light from one or more locations of the body of the subject and deliver the collected light to the optical detector. The monitoring device may include a signal processor configured to receive and process signals produced by the optical detector, a transmitter configured to transmit signals processed by the signal processor to a remote device, and/or an optical filter. | 06-19-2014 |
| 20140303462 | Device for Application of a Sensor to a Measurement Site, a Sensor Head, a Kit of an Application Device and Sensor and Use of an Application Device for Optical Measurement of Physiological Parameters - A device for applying a sensor to a measurement site on a patient's skin has a wall arrangement defining an applicator volume above the patient's skin The wall arrangement has a patient's side and a sensor side. At least one gas-permeable membrane separates the applicator volume into a first volume directed to the measuring site at the patient's side of the wall arrangement and a second volume separated from the patient's skin and directed to the sensor side of the wall arrangement. | 10-09-2014 |
| 20140316225 | SYSTEM AND METHOD FOR DETECTING VASCULAR CONTAMINATION BY SURGICAL ANESTHETIC USING NON-INVASIVE IR SPECTROPHOTOMETRY - A system and method for detecting vascular contamination by surgical anesthetic using non-invasive IR spectrophotometry. One embodiment is a method for operating an instrument such as an enhanced pulse oximeter to monitor a patient receiving local anesthetic marked with dye that absorbs infrared light. Light is applied to and detected from tissue of the patient. A signal representative of the detected light is processed to derive patient oxygenation information. The detected light is also processed to derive information representative of the presence of the dye-marked anesthetic. The oxygenation information and the information representative of the presence of anesthetic are displayed. The oxygenation monitoring and display and the anesthetic monitoring and display can occur separately or concurrently. Fluorescing dyes and fluorescence detection approaches are used for anesthetic detection in some embodiments. Other embodiments apply a sequence of light pulses and correlate the applied light pulse sequence to the detected signal to identify the presence of the dye-marked anesthetic. | 10-23-2014 |
| 20150148626 | METHOD FOR DETECTING COLORECTAL CANCER - In-vivo methods and kits for detecting presence of a combination of biomarkers indicating colorectal cancer are described. One of the methods includes inserting into a patient a combination of binding agents comprising one binding agent having high affinity to CEACAM5 and at least one binding agent having high affinity to at least one of two biomarkers selected from Olfactomedin 4- (OLFM4) and S100P. The method further includes inserting into the patient an in-vivo sensing device, detecting an optical change using the in-vivo sensing device, which occurs when at least one of the combination of binding agents binds to at least one of the corresponding combination of biomarkers, and determining, based on the optical change, presence of colorectal cancer in the patient. | 05-28-2015 |
| 20160015301 | NON-INVASIVE BLOOD ANALYSIS - The present invention provides a personal hand-held monitor (PHHM) comprising a signal acquisition device for acquiring signals which can be used to derive a measurement of a parameter related to the health of the user, wherein the signal acquisition device comprises a blood photosensor having one or more photo-emitters for transmitting light to a body part of a user, one or more photo-detectors for detecting light transmitted through or scattered by the body part and two or more optical cells, at least one of which contains an analyte to be detected or which mimics the absorption spectrum of the analyte, through which the light that has been or will be transmitted through or scattered by the body part passes before it reaches the photo-detector(s). | 01-21-2016 |
| 20160113573 | THERAPY-PROGRESS-LEVEL MONITORING DEVICE AND METHOD - The provided is a therapy-progress-level monitoring device and a method thereof, providing information, in real time during a therapy, regarding the depth of extracellular photodynamic therapy. A photodynamic therapy progress-level monitoring device includes an irradiation unit configured to irradiate, with excitation light of a wavelength capable of exciting a photosensitive substance, a photosensitive substance distributed and sustainably supplied by vascular permeability in the extracellular fluid and the transcellular fluid of a living body; detection units configured to detect the fluorescence intensity produced when the photosensitive substance excited by a reaction between the excitation light and the photosensitive substance is inactivated into a ground state; a depth calculation unit configured to calculate in real time an indicator value estimating the volume or the depth of a therapy region by using the fluorescence intensity; and output units configured to output the indicator value in real time to a display or a storage. | 04-28-2016 |
