| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 568027000 | Oxygen bonded directly to sulfur (e.g., sulfoxides, etc.) | 43 |
| 20090005601 | Process for preparing low malodor dimethyl sulfoxide - The disclosed process relates to the removal of malodorous compounds from dimethyl sulfoxide. | 01-01-2009 |
| 20150051424 | METHOD OF PRODUCING TRIMETHYLSULFOXONIUM BROMIDE AND A METHOD OF TEMPERATURE CONTROL OF REACTION SYSTEM PRODUCING TRIMETHYLSULFOXONIUM BROMIDE - The present invention relates to a method of producing trimethylsulfoxonium bromide by reacting dimethyl sulfoxide with methyl bromide (MeBr), wherein MeBr is added in a manner that satisfies conditions (1) and (2): (1) MeBr is added at an addition rate that complies with a predetermined feeding profile, (2) MeBr is added upon the temperature in the reaction system reaching a predetermined maximum temperature. | 02-19-2015 |
| 20150126780 | DMSO PURIFICATION - Methods and apparatus for purifying DMSO are disclosed including a method of purifying DMSO involving providing a first DMSO composition having impurities; freezing a portion of the first DMSO composition on a first surface to form a second DMSO composition having higher DMSO purity than the first DMSO composition such that a third DMSO composition remains from the unfrozen portion of the first DMSO composition; separating the second DMSO composition from the third DMSO composition; and melting a portion of the second DMSO composition. The freezing of the portion of the first DMSO composition, the separating of the second DMSO composition from the third DMSO composition, and the melting of the portion of the second DMSO composition may happen simultaneously. DMSO purification apparatus employing such methods and other methods are also taught. | 05-07-2015 |
| 20160083340 | METHOD OF PURIFYING DIMETHYL SULFOXIDE - A method of purifying dimethyl sulfoxide economically and at good yield satisfies the specifications of the United States Pharmacopoeia and reduces odor. The method includes distilling a solution having 35 parts by weight or more of water admixed per 100 parts by weight of raw dimethyl sulfoxide. | 03-24-2016 |
| 568028000 | Plural oxygens bonded directly to the same sulfur (e.g., sulfones, etc.) | 38 |
| 20080269527 | ISOTOPICALLY TAGGED SYNONS FROM 2 CARBON PRECURSORS - The use of vinyl sulfides, sulfoxides and sulfones in synthetic chemistry for the production of a wide variety of materials is well known. For example, phenyl vinyl sulfides, sulfoxides and sulfones have been used for the synthesis of important heterocycles, in combinatorial chemistry and as Diels-Alder adducts. Although these compounds have been used extensively for a variety of applications, the isotopically labeled versions have not been reported. A simple route for the isotopically labeled production of these important building blocks has been developed. | 10-30-2008 |
| 20090299100 | Fossil Fuel Desulfurization - A method for oxidizing an organic sulfide by combining an alkali borate, a solvent, hydrogen peroxide, and the organic sulfide, and allowing the alkali borate, the hydrogen peroxide, and the organic sulfide to interact to produce an oxidized organic sulfide. | 12-03-2009 |
| 20110257438 | SULFONE COMPOUND - It is an object of the present invention to provide an aprotic polar solvent mainly useful as a solvent for an electrochemical device, and having a comparatively low melting point and excellent thermal stability. | 10-20-2011 |
| 20110306797 | SULFONE COMPOUND - It is an object of the present invention to provide an aprotic polar solvent mainly useful as a solvent for an electrochemical device, and having a comparatively low melting point and excellent thermal stability. | 12-15-2011 |
| 20120136175 | PROCESS FOR PREPARATION OF ALKYL SULFONE COMPOUNDS - An object of the present invention is to provide a method for preparation of an alkyl sulfone compound simply and safely with high yield, and an alkyl sulfone compound. | 05-31-2012 |
| 20120157717 | METHODS AND COMPOSITIONS FOR PRODUCING LINEAR ALKYL BENZENES - Compositions and methods for producing hydrocarbons using recombinant cells are described herein. Also described herein are recombinant cells, recombinant cell cultures and methods for producing linear alkyl benzenes (LABs) using hydrocarbons produced by such recombinant cell cultures. | 06-21-2012 |
| 20150353442 | METHOD FOR PRODUCING OLEFIN - The present invention relates to a process for producing olefins, including the step of subjecting an alcohol having not less than 8 and not more than 22 carbon atoms to dehydration reaction in the presence of a solid acid catalyst, in which the solid acid catalyst includes aluminum oxide and an oxide of an element having an electronegativity higher than that of aluminum which is supported on the aluminum oxide. | 12-10-2015 |
| 568029000 | Thiol or thioether containing | 2 |
| 20110015441 | SULFONE COMPOUND AND PROCESS FOR PRODUCING CAROTENOID USING THE SAME COMPOUND - The present invention relates to a process for producing a sulfone compound of the following formula (3), characterized in that an allyl sulfone compound of the formula (1) and an allyl halide compound of the formula (2) are reacted in an organic solvent in the presence of an alkali metal hydroxide and a phase-transfer catalyst: | 01-20-2011 |
| 20140357896 | SULFONIUM SALT AND PHOTO-ACID GENERATOR - Provided is a novel sulfonium salt that has high solubility in a solvent and has high light sensitivity to, especially, light having a wavelength not longer than deep-UV (254 nm) and a novel photo-acid generator comprising the sulfonium salt. The invention relates to a sulfonium salt represented by the following general formula (1) and a novel photo-acid generator comprising the sulfonium salt. | 12-04-2014 |
| 568030000 | Nitrogen containing | 2 |
| 20080281127 | PROCESS FOR PREPARATION OF ISOSULFAN BLUE - A process for the preparation of isosulfan blue (Active Pharmaceutical Ingredient) is provided. A process is also provided for preparation of the intermediate, 2-chlorobenzaldehyde-5-sulfonic acid, sodium salt of formula (2), used in the preparation thereof and a procedure for the isolation of benzaldehyde-2,5-disulfonic acid, di-sodium salt of the formula (3). Also provided is a process for the preparation of an isoleuco acid of formula (4), which upon mild oxidation gives rise to isosulfan blue of pharmaceutical grade which can be used for preparation of pharmaceutical formulations. The isolation and purification procedures provided in the process provide substantially pure isosulfan blue with HPLC purity 99.5% or greater. | 11-13-2008 |
| 20100152492 | PROCESS FOR THE CRYSTALLISATION OF MESOTRIONE - The invention relates to a process for selectively controlling the crystallisation mesotrione [2-(4-methylsulphonyl-2-nitrobenzoyl)cyclohexane-1,3-dione] from aqueous solution in which the aqueous mesotrione solution is introduced to a crystalliser containing seed crystals predominantly of the thermodynamically stable polymorph (“Form 1”) in a semi-continuous or continuous manner. The invention further relates to a process for converting the metastable polymorph (“Form 2”) of mesotrione to Form 1 by introducing an aqueous solution containing the former form to a crystalliser containing seed crystals predominantly of the latter form. | 06-17-2010 |
| 568031000 | Carbonyl containing (e.g., ketone containing, etc.) | 5 |
| 20090318732 | Dialdehyde compound, preparation method thereof, and synthetic method of carotenoids using the same - The novel C dialdehyde compound which can be efficiently utilized in the synthesis of carotenoid compounds based on the sulfone chemistry, the preparation method of the same, and the expeditious and practical synthetic processes for lycopene and β-carotene by the use of the above novel compound are disclosed. The syntheses of lycopene and β-carotene are characterized by the processes of the coupling reaction between two equivalents of geranyl sulfone or cyclic geranyl sulfone and the above C dialdehyde, the functional group transformation reactions of the diol in the resulting C 40 coupling products to X's (either halogens or ethers), and the double elimination reactions of the functional groups of the benzenesulfonyl and X to produce the fully conjugated polyene chain of the carotenoids. | 12-24-2009 |
| 20100022802 | Preparation of Alkylaromatic Hydrocarbons and Alkylaryl Sulfonates - An alkylaromatic hydrocarbon composition prepared by the process which comprises oligomerizing an olefin selected from the group consisting of propylene, n-butene and mixtures thereof over an oligomerization catalyst, to form a oligomerization product comprising at least 95% by weight of mono-olefin oligomers of the empirical formula: | 01-28-2010 |
| 20100069675 | SYNTHESIS OF [1-13C]PYRUVIC ACID], [2-13C]PYRUVIC ACID], [3-13C]PYRUVIC ACID] AND COMBINATIONS THEREOF - The present invention is directed to the labeled compounds, | 03-18-2010 |
| 20110015442 | SULFONE COMPOUND AND METHOD FOR PRODUCING THE SAME - The present invention relates to a process for producing a sulfone compound represented by formula (1), which comprising a step of obtaining a compound represented by formula (4) by reacting a compound represented by formula (3) with a chlorate or a bromate, and then resulting reaction solution with HX or X | 01-20-2011 |
| 20160031808 | PROCESSES FOR THE PREPARATION OF (S)-1-(3-ETHOXY-4-METHOXYPHENYL)-2-METHANESULFONYLETHYLAMINE - Provided herein are new processes for the preparation of aminosulfone intermediates for the synthesis of 2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione, which is useful for preventing or treating diseases or conditions related to an abnormally high level or activity of TNF-α. Further provided herein are processes for the commercial production of (S)-1-(3-ethoxy-4-methoxyphenyl)-2-methanesulfonylethylamine. | 02-04-2016 |
| 568032000 | Oxy containing | 9 |
| 20100010266 | Resin cross-linking - A method of effecting cross-linking of a resin comprises generating vinyl sulfonyl moieties in situ with the resin, said sulfonyl moieties then undergoing a reaction which effects cross-linking of the resin. The vinyl sulfonyl moieties may be generated as a result of a loss of a liquid carrier for the resin to be cross-linked. The cross-linking reaction may result from reaction of the vinyl sulfonyl moieties with nucleophilic groups in the resin composition. The resin may be a co-polymer of a compound of formula (IV) with other olefinically unsaturated monomers. | 01-14-2010 |
| 20100048956 | PROCESS FOR THE RECOVERY OF FLUOROMONOMERS - The invention provides a technique enabling the separation and recovery of an unreacted fluoromonomer from an aqueous fluoropolymer dispersion obtained by emulsion polymerization, without using any extraction solvent, and enabling the prevention of a hydrolysis of —SO | 02-25-2010 |
| 20100274058 | Process for Preparation of 2-[Vinyl (Hetero) Arylsulphonyl] Ethanol Derivatives - The present invention relates to a method of making monomers of the formula X═C(H)—Y—S02-CH2-CH(R)—OH which comprises reacting a compound of the formula Q-Y—S02-CH2-CH(R)—OH with a vinyl-containing organometallic reagent comprising a substituted or unsubstituted moiety X═, wherein X═ is a group selected from CH2=, MeO2C(H)C═, MeO2C(Me)C═ and MeC02C═; Y is an optionally substituted aromatic or heteroaromatic diradical; R is a hydrogen or C1-5 alkyl group; and Q is bromo, chloro, iodo, triflate or tosylate. These monomers are of utility in the preparation of cross-linkable resin compositions | 10-28-2010 |
| 20110166391 | DIALDEHYDE COMPOUND, PREPARATION METHOD THEREOF, AND SYNTHETIC METHOD OF CAROTENOIDS USING THE SAME - The novel C dialdehyde compound which can be efficiently utilized in the synthesis of carotenoid compounds based on the sulfone chemistry, the preparation method of the same, and the expeditious and practical synthetic processes for lycopene and β-carotene by the use of the above novel compound are disclosed. The syntheses of lycopene and β-carotene are characterized by the processes of the coupling reaction between two equivalents of geranyl sulfone or cyclic geranyl sulfone and the above C dialdehyde, the functional group transformation reactions of the diol in the resulting C 40 coupling products to X's (either halogens or ethers), and the double elimination reactions of the functional groups of the benzenesulfonyl and X to produce the fully conjugated polyene chain of the carotenoids. | 07-07-2011 |
| 20110190542 | METHOD FOR THE SULFONYLATION OF A HYDROXYLATED ORGANIC COMPOUND - The subject of the present invention is a method for the sulphonylation of a hydroxylated organic compound. The invention relates more particularly to a method for the trifluoromethanesulphonylation of a hydroxylated organic compound. The invention is especially intended for perfluorinated aliphatic hydroxylated compounds. The method of the invention for the sulphonylation of a hydroxylated organic compound is characterized in that it comprises reacting said compound with a sulphonylation agent in an organic medium and in the presence of a heterogeneous inorganic base. | 08-04-2011 |
| 20140343324 | SYNTHETIC MATRIX FOR CONTROLLED CELL INGROWTH AND TISSUE REGENERATION - Biomaterials containing a three-dimensional polymeric network formed from the reaction of a composition containing at least a first synthetic precursor molecule having n nucleophilic groups and a second precursor molecule having m electrophilic groups wherein the sum of n+m is at least five and wherein the sum of the weights of the first and second precursor molecules is in a range from about 8 to about 16% b weight of the composition, preferably from about 10 to about 15%, more preferably from about 12 to about 14.5% by weight of the composition. In one embodiment, the first and second precursor molecules are polyethylene glycols functionalized with nucleophilic and electrophilic groups, respectively. In a preferred embodiment, the nucleophilic groups are amino and/or thiol groups and the electrophilic groups are conjugated, unsaturated groups. The ratio of the equivalent weights of the electrophilic groups (second precursor molecule) and the nucleophilic groups (first precursor molecule) is in the range of between 0.7 and 1.1, more preferably between 0.8 and 1.0. The first and/or second precursor molecule may be covalently bound to one or more molecules selected from the group consisting of cell adhesion peptides, growth factors, and growth factor-like peptides. | 11-20-2014 |
| 568033000 | Oxy bonded directly to a ring | 3 |
| 20100105953 | Human Adam-10 Inhibitors - The present invention provides compounds useful for inhibiting the ADAM-10 protein, with selectivity versus MMP-1. Such compounds are useful in the in vitro study of the role of ADAM-10 (and its inhibition) in biological processes. The present invention also comprises pharmaceutical compositions comprising one or more ADAM-10 inhibitors according to the invention in combination with a pharmaceutically acceptable carrier. Such compositions are useful for the treatment of cancer, arthritis, and diseases related to angiogenesis. Correspondingly, the invention also comprises methods of treating forms of cancer, arthritis, and diseases related to angiogenesis in which ADAM-10 plays a critical role. | 04-29-2010 |
| 20110207967 | PROCESS FOR THE PREPARATION OF VITAMIN K2 - Using a combination of Kumada, Suzuki and Biellmann chemistry, various menaquinones can synthesised rapidly and with stereochemical integrity offering a new way of preparing these vitamin K2 components for the pharmaceutical market. In one embodiment a process for the preparation of a compound of formula (I) is defined including a step in which (i) a compound of formula (II) is reacted formula (III) wherein R is an alkyl group; LG is a leaving group; m is an integer from 0 to 8; n is an integer of from 0 to 9; and X is hydrogen, halide, hydroxyl or protected hydroxyl; in the presence of a copper, nickel or palladium catalyst. | 08-25-2011 |
| 20120184779 | GELLING AGENT CONTAINING A FLUOROALKYL DERIVATIVE - To provide a gelling agent containing a fluoroalkyl derivative, a small amount of which can gelatinize or solidify various organic solvents. | 07-19-2012 |
| 568034000 | Plural rings containing | 11 |
| 20090131723 | 1-Fluoro-1,1-Bis-(Phenylsulfonyl)Methane and Production Method Thereof - A novel 1-fluoro-1,1-bis(arylsulfonyl)methane is provided which is useful in monofluoromethylation. Also provided is a production method thereof. | 05-21-2009 |
| 20110263902 | PROCESS FOR PREPARING 4,4'-DICHLORODIPHENYL SULFONE - The invention relates to a process for preparing 4,4′-dichlorodiphenyl sulfone, comprising the reaction of monochlorobenzene and liquid sulfur trioxide, wherein the liquid sulfur trioxide used has a boron content of at most 100 ppm based on the total weight of the sulfur trioxide used, including all secondary components. | 10-27-2011 |
| 20110275859 | METHOD FOR MANUFACTURING CONJUGATED AROMATIC COMPOUND - A method for manufacturing a conjugated aromatic compound comprising reacting an aromatic compound (A) wherein one or two leaving groups selected from the group consisting of an iodine atom, a bromine atom and a chlorine atom are bonded to an aromatic ring and the aromatic compound (A) does not have (c1) a group represented by the following formula (10): | 11-10-2011 |
| 20120302795 | PROCESS FOR THE PRODUCTION OF A SULFONE MONOMER - The present invention provides a method for the preparation of polymer grade 4,4′-dichlorodiphenyl sulfone in steps comprising reacting dimethyl sulfate and sulfur trioxide optionally containing a catalyst; reacting the formed dimethyl pyrosulfate with the unreacted sulfur trioxide optionally in the presence of a catalyst; reacting the reaction mixture with monochlorobenzene optionally containing a catalyst; optionally removing unreacted dimethyl sulfate; isolating crude 4,4′-dichlorodiphenyl sulfone using an organic solvent/organic solvent-water mixture; recovering the solvent from mother liquor; optionally recovering the isomeric mixture of dichlorodiphenyl sulfones from mother liquor; optionally, conversion of residual isomeric mixture of dichlorodiphenyl sulfones to a product selected from diphenyl sulfone, 2-aminodiphenyl sulfone; 2,4′-dihydroxydiphenyl sulfone, 4,4′-dihydroxydiphenyl sulfone; optionally recovering monochlorobenzene sulfonic acid and/or monochlorobenzene from the mother liquor; optionally recovering sulfuric acid from the residual liquor; optionally recycling the solvent; and purifying 4,4′-dichlorodiphenyl sulfone from crude followed by crystallization. Further the present invention discloses a process in which isomeric mixture of 4,4′-, 3,4′-, and 2,4′-dichlorodiphenyl sulfone produced during the preparation of 4,4′-dichlorodiphenyl sulfone is converted to value added products such as diphenyl sulfone, 2,4′-dihydroxydiphenyl sulfone, 4,4′-dihydroxydiphenyl sulfone and 2-aminodiphenyl sulfone. | 11-29-2012 |
| 20140039222 | Process for the manufacture of dihalodiphenylsulfones - A process for the preparation of dihalodiphenylsulfones_such as 4,4′-dichlorodiphenyl sulfone or 4,4′-bis-(4-chlorophenylsulfonyl)biphenyl with high regioselectivity, at low temperature and in the absence of toxic reagents by reacting together at least one acid, at least one fluorinated anhydride and at least one halobenzene. The invented process is particularly suited for the manufacture of 4,4′-dichlorodiphenyl sulfone. | 02-06-2014 |
| 20140323765 | Process for Manufacturing Haloaryl Compounds From Mixtures of Isomers of Dihalodiarylsulfone - A process for the manufacture of a haloaryl compound which comprises contacting a mixture of dihalodiarylsulfone isomers [mixture (M)] with sulfuric acid to provide a mixture of haloarylsulfonic acid isomers [mixture (M1)] and reacting mixture (M1) in the presence of water. The process is independent on the manufacturing process of mixture (M) and is advantageous in that the obtained haloaryl compound can be recycled to the first step of a dihalodiarylsulfone manufacturing process. | 10-30-2014 |
| 20150291498 | PROCESS FOR PREPARATION OF MK-7 TYPE OF VITAMIN K2 - Process for preparation of MK-7 type of vitamin K2 is characterized by attaching hexaprenyl chain of “all-trans” configuration to monoprenyl derivative of menadiol following “1+6” synthetic strategy. According to the invention, a-sulfonyl carbanion generated in situ from the protected monoprenyl menadiol of the formula (II), wherein R | 10-15-2015 |
| 20150344418 | HIGH PURITY DIPHENYL SULFONE, PREPARATION AND USE THEREOF FOR THE PREPARATION OF A POLY(ARYLETHERKETONE) - The presence of certain impurities in diphenyl sulfone have a deleterious effect on the properties of the poly(aryletherketone)s produced therein, including one or more of color, melt stability, molecular weight, crystallinity, etc. and here identify those impurities and provide processes for the recovery of the diphenyl sulfone. | 12-03-2015 |
| 20160122296 | PROCESS FOR THE OXIDATION OF SULFOXIDES - The present invention relates to a process for oxidizing a sulfoxide to the respective sulfone, said process comprising reacting the sulfoxide with hydrogen peroxide in the presence of a catalyst, obtaining a mixture (M) comprising the sulfone and the catalyst, wherein the catalyst comprises a porous titanium-containing silicate as a catalytically active material. | 05-05-2016 |
| 20220135521 | PROCESS FOR PRODUCING 4,4'-DICHLORODIPHENYL SULFOXIDE - The invention relates to a process for producing 4,4′-dichlorodiphenyl sulfoxide comprising: (a) reacting thionyl chloride, chlorobenzene and aluminum chloride in a molar ratio of thionyl chloride:chlorobenzene:aluminum chloride of 1:(6 to 9):(1 to 1.5) at a temperature in the range from 0 to below 20° C., forming an intermediate reaction product and hydrogen chloride, (b) mixing aqueous hydrochloric acid and the intermediate reaction product at a temperature in the range from 70 to 110° C. to obtain a crude reaction product comprising 4,4′-dichlorodiphenyl sulfoxide, (c) separating the crude reaction product into an organic phase comprising the 4,4′-dichlorodiphenyl sulfoxide and an aqueous phase, (d) washing the organic phase with an extraction liquid. | 05-05-2022 |
| 20220135522 | A PROCESS FOR OBTAINING 4,4'-DICHLORODIPHENYL SULFOXIDE - The invention relates to a process for obtaining 4,4′-dichlorodiphenyl sulfoxide from a liquid mixture comprising dichlorodiphenyl sulfoxide and a solvent, comprising: (a) cooling the liquid mixture to a temperature below the saturation point of 4,4′-dichlorodiphenyl sulfoxide in the solvent to obtain a suspension comprising crystallized 4,4′-dichlorodiphenyl sulfoxide, (b) solid-liquid-separation of the suspension to obtain a residual moisture containing solid 4,4′-dichlorodiphenyl sulfoxide as a product and mother liquor, (c) concentrating the mother liquor, (d) recycling at least a part of the concentrated mother liquor into the cooling step (a). | 05-05-2022 |
| 568035000 | Plural halogens containing | 2 |
| 20100022803 | Method for Producing Tris(Perfluoroalkanesulfonyl)Methide Acid Salt - There is provided a method for producing a tris(perfluoroalkanesulfonyl)methide acid salt represented by formula [1], including the steps of (a) reacting a methylmagnesium halide represented by formula [2] with a perfluoroalkanesulfonyl fluoride represented by formula [3], thereby obtaining a reaction mixture; and (b) directly reacting the obtained reaction mixture with at least one selected from the group consisting of alkali metal halides, quaternary ammonium salts, and quaternary phosphonium salts. By this method, it is possible to easily produce the target methide acid salt with high yield. | 01-28-2010 |
| 20110263903 | PROCESS FOR PREPARING 4,4'-DICHLORODIPHENYL SULFONE - The invention relates to a process for preparing 4,4′-dichlorodiphenyl sulfone proceeding from monochlorobenzene, wherein the content in the monochlorobenzene used of hydrocarbons having from 5 to 8 carbon atoms is at most 100 ppm; based on the total weight of the monochlorobenzene used, including the secondary components. | 10-27-2011 |
| 568036000 | Nitrogen or plural sulfurs containing | 1 |
| 20100099917 | Integrin modulators and methods for their use - 1,5-Dithiaocta-2,7-diene-5-oxide-1-yl(DODOyl) compounds and derivatives thereof, referred to collectively as DODOyl-derived compounds (DDCs), and chiral enantiomers and derivatives thereof, are described, which are integrin modulators that modulate integrin-mediated functions and/or processes. Pharmaceutical compositions containing integrin modulators and chiral enantiomers thereof, and methods for using integrin modulators and chiral enantiomers thereof are further described. | 04-22-2010 |
