| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 564374000 | The chain consists of two or more carbons which are unsubstituted or have acyclic hydrocarbyl substituents only | 19 |
| 20080312471 | Polymorphs of atomoxetine hydrochloride - The present invention provides novel crystalline polymorph forms of atomoxetine hydrochloride denominated Forms B and C and methods for their preparation, as well as methods for the preparation of Form A. The present invention provides pharmaceutical compositions that comprise atomoxetine hydrochloride Form B, Form C, or mixtures thereof that can be used to treat attention deficit/hyperactivity disorder. | 12-18-2008 |
| 20100298606 | PROCESS FOR PREPARING CINACALCET HYDROCHLORIDE - The invention relates to an improved process for preparing cinacalcet hydrochloride. The invention provides an efficient and economic process for preparing cinacalcet hydrochloride which is suitable for industrial implementation i.e., affords cinacalcet hydrochloride with high purity, and uses small volumes of acidifying agent and solvents. The invention also related to a process for preparing a cinacalcet carboxylate salt, including cinacalcet acetate | 11-25-2010 |
| 20110105798 | SYNTHESIS OF CHIRAL AMINES - The instant invention involves the enantioselective hydrogenation of isomeric N—H imines (N-unsubstituted) using a transition metal based catalyst modified with a chiral phosphine derivative to produce enantiomerically enriched chiral amines. | 05-05-2011 |
| 20130096347 | NOVEL PROCESS FOR PREPARING HIGHLY PURE TAPENTADOL OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF - Provided herein is a novel, commercially viable and industrially advantageous process for the preparation of 3-[(1R,2R)-3-(dimethylamino)-1-ethyl-2-methylpropyl]phenol (Tapentadol), or a pharmaceutically acceptable salt thereof, and its intermediates, in high yield and purity. Provided also herein are novel solid state forms of tapentadol intermediates and processes for their preparation thereof. Provided further herein is a purification process for preparing highly pure tapentadol hydrochloride. | 04-18-2013 |
| 20130137900 | NOVEL METHOD OF PREPARING SECONDARY AMINE COMPOUND USING MICROFLOW REACTOR - Disclosed is a novel method of preparing a secondary amine compound using a microflow reactor. According to the method, a primary amine compound and a halide compound are allowed to react with each other in the microflow reactor, such that the production of a tertiary amine compound or an ammonium salt is minimized, whereby the secondary amine compound is efficiently prepared. | 05-30-2013 |
| 20130150622 | STEREOSELECTIVE SYNTHESIS OF TAPENTADOL AND ITS SALTS - A process for the synthesis of a salt of tapentadol. | 06-13-2013 |
| 20160009635 | PROCESS FOR PREPARING SUBSTITUTED PHENYLALKANES | 01-14-2016 |
| 20160200664 | Process for Preparing Cinacalcet and Pharmaceutically Acceptable Salts Thereof | 07-14-2016 |
| 564375000 | Forming amine group directly by reduction, other than by reductive amination | 4 |
| 20100094055 | PROCESS FOR THE PREPARATION OF PHENETHYLAMINE DERIVATIVES - The present invention relates to an improved process for the preparation of essentially pure Venlafaxine Hydrochloride. Particularly, the process for the preparation of Venlafaxine Hydrochloride comprises the following steps: i) Preparation of 1-[Cyano-1-(4-methoxyphenyl)methyl]cyclohexanol, ii) Preparation of crude Venlafaxine Hydrochloride by reduction of 1-[Cyano-1-(4-methoxyphenyl)methyl]cyclohexanol with Alkali metal borohydride and Lewis acid and subsequent conversion to Venalfaxine hydrochloride with formic acid and paraformaldehyde and finally iii) Purification of crude Venlafaxine Hydrochloride. | 04-15-2010 |
| 20110306793 | Process for Preparing Substituted 3-(1-amino-2-methylpentane-3-yl)phenyl Compounds - A process for the preparation of substituted 3-(1-amino-2-methylpentane-3-yl)phenyl compounds. | 12-15-2011 |
| 20130338399 | Process for Preparing Substituted 3-(1-amino-2-methylpentane-3-yl)phenyl Compounds - A process for the preparation of substituted 3-(1-amino-2-methylpentane-3-yl)phenyl compounds which has advantages over conventional processes with respect to higher conversions and yields, flexibility, a shorter overall route, environmentally acceptable conditions, influence of stereoselectivity such as diastereoselectivity in a targeted manner and at least partial suppression of the formation of undesired side-products and/or undesired stereoisomers, in particular undesired diastereomers. | 12-19-2013 |
| 20170233330 | Process for the preparation of 3-[(1R,2R)-3-(Dimethylamino)-1-ethyl-2-methylpropyl]-phenol | 08-17-2017 |
| 564376000 | Forming directly by amination which replaces halogen | 1 |
| 20120142967 | PROCESSES FOR THE PREPARATION OF 5-HT2C RECEPTOR AGONISTS - The present invention relates to processes and intermediates useful in the preparation of (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine (lorcaserin), a serotonin (5-HT) receptor modulator that is useful in the treatment of, for example, central nervous system disorders, such as obesity. | 06-07-2012 |
| 564378000 | The aryl ring or ring system is polycyclo | 2 |
| 20110306794 | PROCESS FOR PREPARING CINACALCET HYDROCHLORIDE - A process for preparing N-[(1R)-1-(1-naphthyl)ethyl]-3-[3-(trifluoromethyl)-phenyl]propan-1-amine hydrochloride salt of formula (I) | 12-15-2011 |
| 564379000 | Tricyclo ring system | 1 |
| 20080242892 | PROCESS FOR PREPARATION OF 5H DIBENZO[a,d] CYCLOHEPTENE DERIVATIVES - A process for preparation of protriptyline hydrochloride from 5-dihydrobenzocycloheptatriene of formula (1) by coupling with chloropropyl alcohol in the presence of excess n-butyl Lithium in tetrahydrofuran under inert atmosphere, followed by preparation of mesylate derivative of formula (3) and finally the nucleophilic displacement of the mesylate group by reacting methylamine solution in methanol to give protriptyline free base of the formula (4). Also the present process reveals the hydrochloride salt formation and purification of the same to give pure pharmaceutical grade protriptyline hydrochloride with impurities less than 0.1% w/w. | 10-02-2008 |
| 564381000 | Phenethylamines having alpha alkyl substituent | 2 |
| 20100113831 | Highly Pure Crystalline Benzphetamine Hydrochloride and Processes for Preparing - A highly pure crystalline form of benzphetamine hydrochloride and methods for the purification and crystallization of benzphetamine hydrochloride in high yield are disclosed. | 05-06-2010 |
| 20110046416 | PROCESS FOR PREPARATION OF BENZPHETAMINE AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS - The present invention provides a simple method for preparation of benzphetamine and its acid addition salt comprising reaction of methamphetamine hydrochloride of formula (III) with benzyl chloride and treating the isolated benzphetamine of formula (II) with an acid dissolved in an organic solvent to provide benzphetamine acid addition salt, more specifically, benzphetamine hydrochloride of formula (I). | 02-24-2011 |
| 564383000 | The chain contains carbon to carbon unsaturation | 2 |
| 20110319666 | METHOD OF OBTAINING 3,3-DIPHENYLPROPYLAMINES - The invention relates to a method of obtaining 3,3-diphenylpropylamines (I), wherein R | 12-29-2011 |
| 20130060065 | Process for the Dehydration of Substituted 4-Dimethylamino-2-aryl-butan-2-ol Compounds and Process for the Preparation of Substituted Dimethyl-(3-aryl-butyl)- Amine Compounds by Heterogeneous Catalysis - Process for the preparation of substituted dimethyl-(3-aryl-butyl)-amine compounds. The process comprises dehydration by heterogeneous catalysis of substituted 4-dimethylamino-2-aryl-butan-2-ol compounds, to form substituted dimethyl-(3-aryl-but-3-enyl)-amine intermediates, which are then converted by hydrogenation with hydrogen to substituted dimethyl-(3-aryl-butyl)-amine compounds. | 03-07-2013 |
