| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 564080000 | Sulfonamides (i.e., Q-(O=)S(=O)-HNH, wherein Q is a substituent and wherein any substituent replacing one or both hydrogens shown will be referred to as E) | 34 |
| 20080200724 | Process and Compound - The present invention relates to a process for preparing certain sulphonamide intermediates useful in the preparation of HIV inhibitors and to the crystal forms thereof. | 08-21-2008 |
| 20090112021 | Preparation of cyclopropyl sulfonylamides - A novel process for the preparation of cyclopropyl sulfonamide of the formula I is described. Cyclopropyl sulfonamide is a versatile building block for many biologically active compounds. | 04-30-2009 |
| 20110009668 | POLYFLUOROSULFONAMIDO AMINE AND INTERMEDIATE - Current methods for making polyfluorosulfonamido amines, which involve the use of a diamine reactant, provide low yields and produce an undesirable fluorine containing bis-sulfonamide by-product representing an economic loss. The bis-sulfonamide by-product is particularly undesirable because it shares very similar physical properties with the desired monoamine product thus making isolation of the desired polyfluorosulfonamido amine product difficult and costly. Furthermore, instead of the efficient incorporation of fluorine to make the desired polyfluorosulfonamido amine product, the bis-sulfonamide by-product constitutes a substantial loss of costly fluorinated starting material. The bis-sulfonamide by-product also constitutes an undesirable impurity that can worsen surfactancy, repellency, or other performance characteristics of the desired polyfluorosulfonamido amine product. The present invention provides a method of making a polyfluorosulfonamido amine without the production of a bis-sulfonamide by-product by reacting a polyfluoroalkylsulfonic compound with a monoamino amide rather than with a diamine reactant as in previously known methods. | 01-13-2011 |
| 20130261339 | Polymorphic Form of N-(S)-(3,4-Difluoro-2-(2-Fluoro-4-Iodophenylamino)-6-Methoxyphenyl)-1-(2,- 3-Dihydroxypropyl)Cyclopropane-1-Sulfonamide and uses thereof - Disclosed herein, in certain embodiments, is a crystalline polymorph form A of N—(S)-(3,4-difluoro-2-(2-fluoro-4-iodophenylamino)-6-methoxyphenyl)-1-(2,3-dihydroxypropyl)cyclopropane-1-sulfonamide. Further disclosed herein, in certain embodiments, are pharmaceutical compositions comprising the crystalline polymorph form A of N—(S)-(3,4-difluoro-2-(2-fluoro-4-iodophenylamino)-6-methoxyphenyl)-1-(2,3-dihydroxypropyl)cyclopropane-1-sulfonamide. | 10-03-2013 |
| 564082000 | Plural sulfonamide groups containing or containing plural sulfonyls bonded directly to the same nitrogen | 8 |
| 20120165571 | METHODS FOR PRODUCING BIS(SULFONYL)IMIDE AMMONIUM SALT, BIS(SULFONYL)IMIDE AND BIS(SULFONYL)IMIDE LITHIUM SALT - To provide methods for producing a bis(sulfonyl)imide ammonium salt, a bis(sulfonyl)imide and a bis(sulfonyl)imide lithium salt simply and in good yield. A method for producing a bis(sulfonyl)imide ammonium salt, which comprises reacting a compound of the formula R—CHF—SO | 06-28-2012 |
| 20130066110 | METHOD FOR MANUFACTURING FLUORINE-CONTAINING IMIDE COMPOUND - With this method for manufacturing fluorine-containing imide compounds, a method for manufacturing a fluorine-containing imide compound ((Rf | 03-14-2013 |
| 20130331609 | PRODUCTION PROCESS FOR FLUOROSULFONYLIMIDE AMMONIUM SALT - A compound [II] such as ammonium N,N-di(fluorosulfonyl)imide is obtained by reacting a compound [I] such as N,N-di(chlorosulfonyl)imide and NH | 12-12-2013 |
| 20140343321 | Plasminogen Activator Inhibitor-1 Inhibitors and Methods of Use Thereof to Modulate Lipid Metabolism - The invention relates to plasminogen activator-1 (PAI-1) inhibitor compounds and uses thereof in the treatment of any disease or condition associated with elevated PAI-1. The invention includes, but is not limited to, the use of such compounds to modulate lipid metabolism and treat conditions associated with elevated PAI-1, cholesterol, or lipid levels. | 11-20-2014 |
| 20150126778 | SYNTHESIS OF FLUOROTRIFLUOROMETHYLSULFONYL IMIDE - The invention provides a method for producing fluorotrifluoromethylsulfonyl imide (FTFSI) by reacting non-fluorohalogenated trihalomethylsulfonyl imide (XTXSI) with hydrogen fluoride, where each X is independently a nonfluoro-halide, such as Cl, Br, or I. | 05-07-2015 |
| 20150293445 | NOVEL SULFONIUM SALT COMPOUND, METHOD FOR PRODUCING THE SAME, AND PHOTOACID GENERATOR - Provided is a sulfonium salt compound represented by the following general formula (I): | 10-15-2015 |
| 20160031806 | SYNTHESIS OF TETRABUTYLAMMONIUM BIS(FLUOROSULFONYL)IMIDE AND RELATED SALTS - The present invention is directed to methods comprising adding ammonia, either as an ammonium salt or as a gas at pressures below 0.01 MPa, to a sulfuryl fluoride solution to form the anion of bis(fluorosulfonyl)amine under conditions well suited for large-scale production. The bis(fluorosulfonyl)amine so produced can be isolated by methods described in the prior art, or isolated as an organic ion pair, such as an alkylammonium solid salt, or as an ionic liquid. | 02-04-2016 |
| 564083000 | Two sulfonamido sulfonyls having no sulfonamido nitrogen between the sulfonyls | 1 |
| 20120253070 | SURFACE MODIFIED MATERIAL, SULFONIMIDE COMPOUND FOR SURFACE MODIFICATION, AND FUEL CELL - There are provided a surface modified material comprising a base material, and one or more kinds of sulfonimide compound groups bonded onto the surface of the base material via one or more linking groups -A-Y′— (A is a direct bond or an organic group. Y′ is a bonding site with the base material.); the sulfonimide compound group comprising, in its molecular structure, one or more linking groups -A—Y′— and two or more sulfonimide groups; as well as a fuel cell using the surface modified material for a catalyst layer. There is also provided a sulfonimide compound for surface modification comprising one or more reactive end groups -A-Y (A is a direct bond or an organic group. Y is a reactive functional group.) and two or more sulfonimide groups. | 10-04-2012 |
| 564084000 | Substituent Q contains benzene ring | 13 |
| 20090306428 | Process for the Synthesis of C-2, C-3 Substituted N-Alkylated Indoles Useful as cPLA2 Inhibitors - The present invention provides method for making a compound of formula 1: | 12-10-2009 |
| 564086000 | Nitrogen in substituent Q | 8 |
| 20080319225 | Method of Preparation of (R)-(-)-5(2-Aminopropyl)-2-Methoxybenzenesulfonamide - A method of preparation of (R)-(−)-5-(2-aminopropyl)-2-methoxybenzenesulfonamide of formula I and its use for production tamsulosin. A protective group is introduced to N-[(1R)-2(4-methoxyphenyl)-1-methylethyl]-N-[(1R)-1-phenylethyl)]amine and the resulting amide of formula IX is chlorosulfonated and the resulting sulfochloride is converted to a sulfonamide of formula X, from which the compound of formula I is obtained by hydrogenation. | 12-25-2008 |
| 20090137844 | Crystallization process - The invention relates to a process for the production of tamsulosin hydrochloride crystals where the crystal size distribution is controlled by controlling the temperature where hydrochloric acid is added to the reaction mixture. | 05-28-2009 |
| 20100048950 | Glucocorticoid Mimetics, Methods of Making Them, Pharmaceutical Compositions and Uses Thereof - Compounds of Formula (I) | 02-25-2010 |
| 20100069668 | 5-[(2R)-[2-[2-(2,2,2-TRIFLUOROETHOXY)PHENOXY]ETHYL]AMINO]PROPYL]-2-METHOXY- BENZENESULFONAMIDE - 5-[(2R)-[2-[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl]amino]propyl]-2-methoxybenzenesulfonamide, a pharmaceutical composition containing the compound, and the synthesis method thereof. The compound has strong antagonism toward α1-adrenceptor and has high selectivity toward smooth muscle of urethra. | 03-18-2010 |
| 20100267987 | Process for Preparing Tamsulosin Hydrochloride - The invention relates to an process for preparing Tamsulosin hydrochloride of Formula (I) which comprises (i) reacting (R)-(−)-5-(2-amino-propyl)-2-methoxybenzenesulfonamide of Formula (II) with substituted phenoxy compound of Formula (III), wherein Z represents a removing group, such as —OSO | 10-21-2010 |
| 564087000 | Nitro or nitroso in substituent Q | 3 |
| 20080312469 | PREPARATION OF 2S,3S-N-ISOBUTYL-N-(2-HYDROXY-3-AMINO-4-PHENYLBUTYL)-P-NITROBENZENESULFONYLAMIDE HYDROCHLORIDE AND OTHER DERIVATIVES OF 2-HYDROXY-1,3-DIAMINES - The present invention provides a new process for the preparation of 2S,3S—N-isobutyl-N-(2-hydroxy-3-amino-4-phenylbutyl)-p-nitrobenzenesulfonylamide hydrochloride, wherein this compound is prepared directly from the chloromethylalcohol. Importantly, the process of the present invention results in higher yields of 2S,3S—N-isobutyl-N-(2-hydroxy-3-amino-4-phenylbutyl)-p-nitrobenzenesulfonylamide hydrochloride without sacrificing its purity. The processes of the present invention can be used to prepare not only the 2S,3S-derivative, but also the 2R,3S-, 2S,2R- and the 2R,3R-derivatives. | 12-18-2008 |
| 20090275779 | METHOD FOR PRODUCING OPTICALLY ACTIVE BENZYLAMINE DERIVATIVE - The present invention relates to a method for producing an optically active benzylamine derivative which is useful as an intermediate for pharmaceutical products and the like. In the present invention, an optically active benzylalcohol derivative is reacted with a sulfonylamide derivative in the presence of a phosphine derivative and an azodicarbonyl compound, to obtain an optically active benzylsulfonylamide derivative as a novel compound. Then, the thus-obtained optically active benzylsulfonylamide derivative is reacted with a thiol derivative, thereby producing an optically active benzylamine derivative. According to the present invention, the compound can be easily produced by a simple and short process without racemization. | 11-05-2009 |
| 20100286444 | PREPARATION OF 2R,3S-N-ISOBUTYL-N-(2-HYDROXY-3-AMINO-4-PHENYLBUTYL)-P-NITROBENZENESULFON- YLAMIDE HYDROCHLORIDE AND OTHER DERIVATIVES OF 2-HYDROXY-1,3-DIAMINES - The present invention provides a new process for the preparation of 2R,3S-N-isobutyl-N-(2-hydroxy-3-amino-4-phenylbutyl)-p-nitrobenzenesulfonylamide hydrochloride, wherein this compound is prepared directly from the chloromethylalcohol. Importantly, the process of the present invention results in higher yields of 2R,35-N-isobutyl-N-(2-hydroxy-3-amino-4-phenylbutyl)-p-nitrobenzenesulfonylamide hydrochloride without sacrificing its purity. The processes of the present invention can be used to prepare not only the 2R,3S-derivative, but also the 2S,3S-, 2S,2R- and the 2R,3R-derivatives. | 11-11-2010 |
| 564088000 | Carbonyl in substituent Q | 1 |
| 20100094052 | PROCESS FOR PREPARING ACYLSULFAMOYLBENZAMIDES - The invention relates to a process for the preparation of a compound of formula (I): | 04-15-2010 |
| 564090000 | Substituent Q is monocyclic | 3 |
| 564092000 | Benzene ring in a substituent E | 2 |
| 20130211139 | PROCESS FOR PRODUCING OPTICALLY ACTIVE BETA-AMINO ALDEHYDE COMPOUND - The invention relates to a method of producing optically active β-aminoaldehyde compound (3) by reacting imine compound (1-1) or sulfone compound (1-2) with aldehyde compound (2) in the presence of an optically active pyrrolidine compound. | 08-15-2013 |
| 20140039220 | METHOD FOR PRODUCING DIAMINE COMPOUND - The present invention provides a method for producing a compound represented by general formula (1) (wherein R | 02-06-2014 |
| 564094000 | Nitrogen in an acyclic substituent E | 1 |
| 20100063322 | NOVEL POLYAMINE DERIVATIVES - A compound having the general formula (I) or a pharmacologically acceptable salt thereof: | 03-11-2010 |
| 564095000 | Substituent Q is acyclic | 9 |
| 564096000 | Halogen in substituent Q attached indirectly to the sulfonamide sulfur by nonionic bonding | 8 |
| 20090143621 | Method of Forming Alkoxylated Fluoroalcohols - A method of forming an alkoxylated fluoroalcohol is accomplished by providing a boron compound having or providing at least one boron-oxygen bond and an iodine source. The boron compound and iodine source are combined with reactants of a fluoroalcohol and an alkylene oxide in the presence of a base. The reactants are allowed to react to form an alkoxylated fluoroalcohol reaction product. | 06-04-2009 |
| 20110092735 | METHODS USING AMPHOTERIC SURFACTANTS - A method of providing a surface effect to a medium or substrate comprising contacting the medium or substrate with a compound of formula (I): | 04-21-2011 |
| 20110237834 | POLYFLUOROALKYLSULFONAMIDO ALKYL HALIDE INTERMEDIATE - The present invention relates to a polyfluoroalkylsulfonamido alkyl halide intermediate. The invention also relates to the use of the aforementioned halide intermediate to prepare a mixture of polyfluoroalkylsulfonamido alkyl amines including at least one polyfluoroalkylsulfonamido alkyl amine and its analog, a di(polyfluoroalkylsulfonamido alkyl) amine. | 09-29-2011 |
| 20120071689 | PRODUCTION PROCESSES AND SYSTEMS, COMPOSITIONS, SURFACTANTS, MONOMER UNITS, METAL COMPLEXES, PHOSPHATE ESTERS, GLYCOLS, AQUEOUS FILM FORMING FOAMS, AND FOAM STABILIZERS - Production processes and systems are provided that include reacting halogenated compounds, dehalogenating compounds, reacting alcohol's, reacting olefins and a saturated compounds, reacting reactants having at least two —CF | 03-22-2012 |
| 20130137899 | PROCESS FOR PRODUCING FLUORINE-CONTAINING SULFONYLIMIDE COMPOUND - In this process for producing a fluorine-containing sulfonylimide compound, a process for producing a fluorine-containing sulfonylimide compound ((Rf | 05-30-2013 |
| 20180022694 | PROCESS FOR FLUORINATION OF SULPHONYL HALIDE COMPOUNDS | 01-25-2018 |
| 564097000 | Benzene ring in a substituent E | 2 |
| 20100174113 | AROMATIC SULPHONYLIMIDES, PREPARATION THEREOF AND USE THEREOF AS ELECTROLYTE - The invention relates to a process for preparing aromatic sulphonylimides, to the sulphonylimides obtained, and to the use thereof as salt of an electrolyte. The sulphonylimides correspond to the formula [R—SO | 07-08-2010 |
| 20120245387 | LITHIUM SALTS OF PENTAFLUOROPHENYLAMIDE ANIONS, PREPARATION THEREOF AND USE THEREOF - The present invention provides new lithium salts comprising pentafluorophenylamide anions following the general formula Li | 09-27-2012 |
| 564098000 | Substituent Q is alkyl | 1 |
| 564099000 | Benzene ring in a substituent E | 1 |
| 20130331610 | Halogenated Pyrazolo[1,5-A]Pyrimidines, Processes, Uses, Compositions and Intermediates - The invention provides novel halogenated pyrazolo[1,5-a]pyrimidines of formula (I) wherein R, R | 12-12-2013 |
