| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 562556000 | Sulfur or selenium | 29 |
| 20090023953 | PENTAFLUOROSULFANYL CONTAINING AMINO ACIDS - There are provided SF | 01-22-2009 |
| 20100048948 | GLUTATHIONE PREPARATION AND METHOD FOR PRODUCTION THEREOF - The present invention relates to a method of improving the preservation stability of glutathione, which is characterized by allowing glutathione to co-exist with an arginine-acidic amino acid salt. In addition, the present invention relates to a production method of a glutathione preparation, which is characterized by mixing glutathione and an arginine-acidic amino acid salt. By the production method, a glutathione preparation that resists quality deterioration can be provided. Moreover, the present invention relates to a preservation method of glutathione, which is characterized by allowing glutathione to co-exist with an arginine-acidic amino acid salt. By the preservation method, quality deterioration of glutathione during preservation can be suppressed. | 02-25-2010 |
| 20110124914 | OPTICALLY ACTIVE ALPHA-AMINO ACID INTO WHICH BSH IS INTRODUCED AND METHOD FOR SYNTHESIZING THE SAME - Disclosed is the method for producing an optically active BSH amino acid, which comprises a step of reacting an optically active a-amino acid derivative having a halogen in a side chain with a cyanoethyl BSH compound represented by formula (1). An optically active BSH amino acid obtained by the method is also disclosed. | 05-26-2011 |
| 20120004457 | METHOD FOR PRODUCING PEPTIDE - An object of the present invention is to provide a novel method for producing a peptide utilizing a ligation reaction in which ligation efficiency is excellent and side reactions to other functional groups in the peptide are hard to occur, in comparison with the conventional native chemical ligation methods utilizing the thiol auxiliary group. The present invention provides a method for producing a peptide which comprises a step of causing a first peptide and a second peptide to react in the presence of a reducing agent to obtain a ligated product of the first peptide and the second peptide, wherein the first peptide contains, at the C-terminal end, an amino acid derivative having a thioester group, and the second peptide contains, at the N-terminal end, a serine or threonine derivative having a thiol auxiliary group. | 01-05-2012 |
| 562557000 | Alpha N, beta S - acids or salts thereof | 3 |
| 20110257432 | Metformin-Cysteine Prodrug - A metformin-cysteine prodrug. It is believed that the prodrug of the present invention will transport in the LAT1 and LAT2 transporter system. Because the LAT1 and LAT2 transporters are important and effective transporters of amino acids in both the small intestine and colon, it is believed that the LAT-transportable prodrugs of the present invention will be effectively absorbed both in small intestine and in the colon. The increased absorption window provided by the present invention should result in highly sustained plasma concentrations of metformin, thereby increasing the effectiveness of the medication and allowing for a single daily dose. | 10-20-2011 |
| 20130041177 | NON-CRYSTALLINE OXIDIZED GLUTATHIONE AND PRODUCTION METHOD THEREFOR - A non-crystalline amorphism of oxidized glutathione is produced by drying a crystal of oxidized glutathione hexahydrate at a temperature of 40 to 90° C. | 02-14-2013 |
| 20140024857 | CYSTEINE AMINO-ACID COMPOUND (OR ITS ANALOGUES) USED IN THE DISRUPTION OF MICROBIAL BIOFILMS WHEN TREATING OR PREVENTING DISEASES CAUSED BY PHYTOPATHOGENIC BACTERIA KNOWN TO ATTACK PLANTS OF AGRICULTURAL INTEREST - Cysteine amino-acid compound (or its analogues) used in the disruption of microbial biofilms by treatment of prevention of diseases generated by phytopathogenic bacteria attacking plants of agricultural interest represented by an innovative solution within the agriculture sector, where said compound can be used in the pharmacological form, as a drug associated with fertilizer for the combat of bacterial diseases which form microbial biofilms, such as citrus variegated chlorosis (CVC), citric canker’, huanlongbing (HLB) disease or ‘greening’, amongst other, which inventive concept, as such, never before completed, resides in the benefit deriving from the cysteine amino-acid, and all of its analogues, in the inhibitory action and progressive disruption of the microbial biofilm thus liberating the nutritive flux and hydration of the root to the upper part of the plant and the subsequent regression of the disease symptoms, with the added advantage that the cysteine amino-acid compound is non-toxic, guaranteeing healthy production of foods by plants of agricultural interest that are totally healthy, without toxic residues in their composition, as well as when said compound is applied there is risk to the environment due to the rapid absorption, notably within the area in which it is applied, where such predicates of disease combat, with the exception of toxic collateral effects still guarantee that the final crop and harvest will have a higher productivity per hectare. | 01-23-2014 |
| 562559000 | Methionine per se or salt thereof | 22 |
| 20080242888 | PROCESS FOR PRODUCING METHIONINE - A process for producing methionine by hydrolysis of 5-(β-methylmercaptoethyl)hydantoin in the presence of an alkali, in which the concentration of hydrogen sulfide is 5 ppm or less in a solution used for hydrolysis comprising 5-(β-methylmercaptoethyl)hydantoin and the alkali, whereby methionine can be stably produced for a long period of time. | 10-02-2008 |
| 20090076302 | PROCESS FOR PREPARING a-KETO ACIDS AND DERIVATIVES THEREOF - A method for preparing α-keto acids, especially α-ketomethionine, and/or derivatives thereof, whereby an aldehyde is reacted with thiols to give a corresponding dithioacetal, the dithioacetal formed, is reacted with an electrophile in the presence of a strong base, and the resulting α,α-(dithio)carboxylic acid is solvolyzed with acid-catalysis to release thiol and give the α-keto acid or a derivative thereof. Umpolung of aliphatic or aromatic aldehydes is effected by reaction with thiols. | 03-19-2009 |
| 20090281353 | Use of dimethyl disulfide for methionine production in microoragnisms - The present invention features improved processes and organisms for the production of methionine. The invention demonstrates that a ΔmetF organism or a ΔmetE AmetH organism, for example, mutants of | 11-12-2009 |
| 20090306426 | PROCESS FOR PRODUCING METHIONINE - The present invention provides a process for producing methionine, which comprises steps of:
| 12-10-2009 |
| 20100004486 | PROCESS FOR PRODUCING METHIONINE - The present invention provides a process for producing methionine which is advantageous from the viewpoints of cost and wastewater disposal, and which comprises the following steps (1) to (5): | 01-07-2010 |
| 20100121102 | PROCESS FOR PRODUCING METHIONINE - A process for producing methionine advantageously in view of cost, while efficiently recovering useful components, is provided including the following steps: (1) hydrolyzing 5-[2-(methylthio)ethyl]imidazolidine-2,4-dione in the presence of a basic potassium compound; (2) introducing carbon dioxide into the reaction solution obtained in the step (1) to thereby precipitate methionine, and separating the resulting slurry into a precipitate and a mother liquor; (3) concentrating the mother liquor obtained in the step (2), mixing the resulting concentrate with a lower alcohol, introducing carbon dioxide into the resulting mixture to thereby precipitate methionine and potassium hydrogencarbonate, and separating the resulting slurry into a precipitate and a mother liquor; and (4) concentrating the mother liquor obtained in the step (3), treating the resulting concentrate by heating at a temperature of from 150 to 200° C., and recycling the treated solution for use in step (2). | 05-13-2010 |
| 20100121103 | PROCESS FOR PRODUCING METHIONINE - A process for producing methionine advantageously in view of cost, while efficiently recovering useful components, is provided, including the following steps: (1) hydrolyzing 5-[2-(methylthio)ethyl]imidazolidine-2,4-dione in the presence of a basic potassium compound; (2) introducing carbon dioxide into the reaction solution obtained in step (1) to thereby precipitate methionine, and separating the resulting slurry into a precipitate and a mother liquor; (3) concentrating the mother liquor obtained in step (2), mixing the resulting concentrate with a lower alcohol, introducing carbon dioxide into the resulting mixture to thereby precipitate methionine and potassium hydrogencarbonate, and separating the resulting slurry into a precipitate and a mother liquor; and (4) concentrating the mother liquor obtained in step (3), treating the resulting concentrate by heating at a temperature of from 150 to 200° C., and recycling the treated solution for use in step (3). | 05-13-2010 |
| 20100121104 | PROCESS FOR PRODUCING METHIONINE - A process for producing methionine, while corrosion of a pipe and a reaction vessel is well inhibited, is provided including the following steps (1) to (3), wherein a content of thiols in 3-methylthiopropanal is 500 ppm or less, based on the propanal, and a content of hydrogen sulfide in 3-methylthiopropanal is 60 ppm or less, based on the propanal; step (1) in which 3-methylthiopropanal is reacted with hydrogen cyanide in the presence of a base to give 2-hydroxy-4-methylthiobutanenitrile; step (2) in which the 2-hydroxy-4-methylthiobutanenitrile obtained in step (1) is reacted with ammonium carbonate to give 5-(β-methylmercaptoethyl)hydantoin; and step (3) in which the 5-(β-methylmercaptoethyl)hydantoin obtained in step (2) is hydrolyzed in the presence of a basic potassium compound to give methionine. | 05-13-2010 |
| 20110207962 | PRODUCTION METHOD OF METHIONINE - The present invention aims to provide a method of producing methionine by hydrolyzing M-hydantoin in the presence of a basic potassium compound, which can effectively prevent corrosion of reaction vessels in both the liquid phase and gaseous phase of a hydrolysis solution even at a higher temperature, and enables a longer period of stable production of methionine. Provided is a method of producing methionine, comprising hydrolyzing 5-(β-methylmercaptoethyl)hydantoin in water in the presence of a basic potassium compound in a reaction system having a potassium concentration of not more than 9 wt % at a temperature of not less than 170° C. | 08-25-2011 |
| 20110224458 | PREPARATION OF METHIONINE OR SELENOMETHIONINE FROM HOMOSERINE VIA A 4-SUBSTITUTED 2-AMINOBUTANOIC ACID INTERMEDIATE - Provided herein are processes for the production of methionine or selenomethionine from homoserine. In particular, the processes proceed via the production of 4-substituted 2-aminobutanoic acid intermediates or derivatives thereof. | 09-15-2011 |
| 20110319659 | METHOD FOR PRODUCING METHIONINE - A method for producing methionine includes a hydrolyzing step of hydrolyzing 5-(β-methylmercaptoethyl)hydantoin, and a crystallizing step of crystallizing with carbon dioxide introduced into a reaction solution after hydrolysis, to obtain methionine. In the crystallizing step, as carbon dioxide introduced into the hydrolysis reaction solution, carbon dioxide that is separated in a carbon dioxide separation section from a reformed gas formed by steam reforming reaction in a steam reformation section and carbon dioxide that is separated in an exhaust gas separation section from a combustion exhaust gas generated by pure oxygen combustion in a hydrocarbon heating furnace and a reformation reaction heating furnace are used. | 12-29-2011 |
| 20120123158 | Method for Increasing Methionine Productivity Using a Mixture of Methyl Mercaptan and Dimethyl Sulfide - The present invention relates to a method for increasing L-methionine productivity and organic acid productivity. More particularly, the present invention relates to a method which involves adding a mixture containing methyl mercaptan and dimethyl sulfide at a appropriate ratio to O-acetyl homoserine or O-succinyl homoserine and to an enzyme having an activity of converting methionine precursor into L-methionine, so as to perform an enzyme reaction, to thereby improve the conversion rate of L-methionine and organic acid from the L-methionine precursor, and thus increasing L-methionine yield as compared to conventional method. | 05-17-2012 |
| 20120178966 | METHODS FOR PRODUCTION OF L-METHIONINE AND RELATED PRODUCTS - A method comprising: (a) enzymatically processing an O-acetylhomoserine (OAHS) fermentation liquor to produce L-methionine and an acetate source; (b) separating at least a portion of said L-methionine from at least a fraction of said acetate source to form separated L-methionine and a residual liquor comprising an acetate-source; and (c) recovering at least a portion of said acetate source from said residual liquor as recovered acetate. | 07-12-2012 |
| 20120253068 | PROCESS FOR PRODUCING METHIONINE - Provided is a process for producing methionine, which involves:
| 10-04-2012 |
| 20130006014 | Preparation of Methionine or Selenomethionine from Homoserine via a Lactone Intermediate - Provided herein are processes for the production of methionine or selenomethionine from homoserine. In particular, the processes proceed via the production of lactone intermediates. | 01-03-2013 |
| 20130012737 | PROCESS FOR PRODUCING SULFUR-CONTAINING AMINO ACID OR SALT THEREOF - According to the present invention, a new process for producing a sulfur-containing amino acid without using of hydrogen cyanide or sodium azide which requires careful handling as a raw material can be provided. | 01-10-2013 |
| 20130072713 | METHOD FOR PRODUCING METHIONINE - A novel method for producing methionine without using hydrogen cyanide as a raw material has been demanded. A method for producing methionine including a step A of oxidizing 4-methylthio-2-oxo-1-butanal in the presence of an alcohol; a step B of hydrolyzing a 4-methylthio-2-oxo-butanoic acid ester obtained in the step A; and a step C of subjecting 4-methylthio-2-oxo-butanoic acid obtained in the step B to reductive amination. | 03-21-2013 |
| 20130158292 | METHOD FOR PRODUCING METHIONINE - A novel method capable of producing methionine without using hydrogen cyanide as a raw material has been desired. The present invention relates to a method for producing methionine including Step A of oxidizing 4-methylthio-2-oxo- | 06-20-2013 |
| 20130231503 | Microorganism producing L-methionine precursor and method of producing L-methionine and organic acid from the L-methionine precursor - The present invention relates to a method for producing L-methionine, comprising: i) culturing an L-methionine precursor-producing microorganism strain in a fermentation solution, so that the L-methionine precursor accumulates in the solution; and ii) mixing a converting enzyme and methylmercaptan or its salts with at least a portion of the solution to convert the accumulated L-methionine precursor into L-methionine, as well as to microorganism strains used in each step. | 09-05-2013 |
| 20140155652 | METHOD OF PRODUCING METHIONINE - The invention provides the following method capable of producing methionine in a shorter time by making rapid progress of the hydrolysis of 5-(2-methylmercaptoethyl)hydantoin from an aqueous 5-(2-methylmercaptoethyl)hydantoin solution containing ammonia component. A method of producing methionine is the method comprising hydrolyzing 5-(2-methylmercaptoethyl)hydantoin in an aqueous 5-(2-methylmercaptoethyl)hydantoin solution containing ammonia component, wherein the hydrolysis is performed after the ammonia component is removed from the aqueous solution. | 06-05-2014 |
| 20140213819 | METHOD FOR THE PRODUCTION OF 2-HYDROXY-4-(METHYLTHIO)BUTYRONITRILE FROM 3-(METHYLTHIO)PROPANAL AND HYDROGEN CYANIDE - A method for the production of 2-hydroxy-4-(methylthio)butyronitrile having good storage stability in a multi-zone reactor, is provided. 3-methylmercaptopropionaldehyde is reacted with hydrogen cyanide in the presence of a base as catalyst in a main reaction zone of the multizone reactor to form a reaction mixture comprising the 2-hydroxy-4-(methylthio)butyronitrile, unreacted 3-methylmercaptopropionaldehyde, the catalyst and residual amounts of gaseous hydrogen cyanide. The residual gaseous hydrogen cyanide is removed from the main reaction zone to an absorption and post-reaction zone of the reactor which comprises a mixture of 3-methylmercaptopropionaldehyde and the catalyst; and the gaseous hydrogen cyanide is further reacted with the 3-methylmercaptopropionaldehyde in the absorption and post reaction zone. A molar ratio of hydrogen cyanide to 3-(methylthio)propanal in the main reaction zone is from 0.98 to 1.03. | 07-31-2014 |
| 20160068480 | PROCESS FOR THE PREPARATION OF METHIONINE - This disclosure relates to a process for preparing D,L-methionine by feeding carbon dioxide to an aqueous potassium methioninate solution obtained by hydrolysis of 5-(2-methylmercaptoethyl)hydantoin, in order to precipitate out crude methionine, which is separated off and purified. In this process an aqueous solution of the separated-off crude methionine is purified by recrystallization from a solution containing potassium ions and also a crystallization additive. The crystallization additive is a nonionic or anionic surfactant, or a mixture of different nonionic or anionic surfactants. The recrystallization occurs by introducing a 60 to 110° C.-hot methionine solution into a 35 to 80° C.-warm methionine suspension, a temperature of which is lower than that of the introduced solution, such that the temperature of the methionine suspension being maintained between 35 and 80° C. during the addition. The crystallization additive is a sorbitan fatty acid ester or a mixture of different sorbitan fatty acid esters. | 03-10-2016 |
