| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 558426000 | Benzene ring attached indirectly to the cyano group by nonionic bonding (i.e., alicyclic ring between the benzene ring and the cyano group) | 10 |
| 20090076294 | CONTROLLED NUCLEATION OF SOLUTES IN SOLUTIONS HAVING NET CHARGE TO PROMOTE CRYSTAL GROWTH - This application is concerned with the controlled nucleation of solutes (i.e. dissolved solids) from solution. It has been found that the energy barrier for dissolved solids to nucleate is affected by the surface charge density of the reaction vessel (and hence the mass-to-charge ratio of vessel). The reaction vessel may, for example, comprise a levitated droplet of the solution having an “excess net charge”. That is, ions present in the vessel of a single polarity are in excess of the counterions of opposite polarity. An increase in the surface charge density of the vessel (and hence a reduction in the mass-to-charge ratio of the vessel) causes the barrier for nucleation to decrease. These findings can be exploited using instruments commonly used in wall-less sample preparation to elicit selective control over the induction of nucleation and subsequent crystallization of target solutes of interest in the condensed phase. The ion induced nucleation phenomenon, in reaction vessels having a desirable surface charge density, is likely to be general for all dissolved solids, ranging from inorganic compounds, to low and high molecular weight organic compounds, including proteins and other molecules. For example the present invention can be used to selectively crystallize a target solute or to separate different solutes from one another based on their propensity to nucleate at different reaction conditions. The different solutes could constitute different compounds or different stereochemical forms of same compound. The invention could also be exploited to controllably select or separate polymorphic forms of a compound (which may often have very different biological activity). The crystals derived from the process could be the subject of further analysis, characterization or manipulation, for example as a prepared sample for MALDI-TOF MS. | 03-19-2009 |
| 20100099905 | ADDITIVE FOR NON-AQUEOUS ELECTROLYTE AND SECONDARY BATTERY USING THE SAME - Disclosed is a compound represented by the following formula 1: | 04-22-2010 |
| 20100174104 | COBALT-CATALYZED ASYMMETRIC CYCLOPROPANATION WITH DIAZOSULFONES - Asymmetric cyclopropanation of olefins with diazosulfones. | 07-08-2010 |
| 20120016150 | Process for Producing 3-(2-Cyano-1-propenyl)-2,2- Dimethylcyclopropanecarboxylic Acid or Salt Thereof - A process for producing comprising reacting a 3-formyl-2,2-dimethylcyclopropanecarboxylate and propionitrile in the presence of a base to obtain 3-(2-cyano-1-propenyl)-2,2-dimethylcyclopropanecarboxylic acid or its salt. | 01-19-2012 |
| 20120116112 | PROCESS FOR THE PREPARATION OF FUNCTIONALISED BENZOCYCLOBUTENES, AND APPLICATION IN THE SYNTHESIS OF IVABRADINE AND ADDITION SALTS THEREOF WITH A PHARMACEUTICALLY ACCEPTABLE ACID - Process for the preparation of compounds of formula (IV): | 05-10-2012 |
| 20130204032 | NEW PROCESS FOR THE RESOLUTION OF ENANTIOMERS OF (3,4 DIMETHOXY-BICYCLO[4.2.0]OCTA-1,3,5-TRIEN-7-YL)NITRILE AND APPLICATION IN THE SYNTHESIS OF IVABRADINE - Process for the optical resolution of the compound of formula (I): | 08-08-2013 |
| 20130331597 | AMIDATION PROCESS - This invention describes an amidation process whereby perfluorinated amino acids can be activated and treated with an amine in the presence of a coupling agent and a pyridine derivative to yield amides, without loss of optical purity. | 12-12-2013 |
| 20160075645 | AMIDATION PROCESS - This invention describes an amidation process whereby perfluorinated amino acids can be activated and treated with an amine in the presence of a coupling agent and a pyridine derivative to yield amides, without loss of optical purity. | 03-17-2016 |
| 20170233333 | PROCESS FOR THE SYNTHESIS OF (+) AND (-)-1-(3,4-DICHLOROPHENYL)-3-AZABICYCLO[3.1.0]HEXANE | 08-17-2017 |
| 558427000 | Polycyclo ring system having at least three cyclos, at least one of which is a benzene ring | 1 |
| 20120289734 | ALTERNATIVE SYNTHESIS OF 1,1-SUBSTITUTED OLEFINS HAVING ELECTRON-WITHDRAWING SUBSTITUENTS - A three-stage method for synthesizing 1,1-disubstituted olefins is provided. | 11-15-2012 |
