| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 558087000 | Processes | 73 |
| 20090054675 | Process for the alkylation of phosphorus-containing compounds - A process for alkylating a phosphorus-containing compound to provide an alkylated phosphorus-containing compound is provided which comprises alkylating 5 phosphorus-containing compound possessing at least one phosphorus-hydrogen alkylatable site with reactant which generates alkene and/or cycloalkene alkylating agent in situ in the presence of initiator, the alkylene and/or cycloalkylene alkylating agent alkylating the phosphorus-containing component to provide alkylated phosphorus-containing product. | 02-26-2009 |
| 20100004477 | NOVEL CRYSTAL OF 5-AMINOLEVULINIC ACID PHOSPHATE AND PROCESS FOR PRODUCING THE SAME - To provide a novel crystal of 5-aminolevulinic acid phosphate having a high thermal stability, a high melting point, and an excellent moisture absorption resistance as well as a process for producing the same. | 01-07-2010 |
| 20100113817 | PHOSPHORYLCHOLINE GROUP-CONTAINING COMPOUND, METHOD OF MANUFACTURING A PHOSPHORYLCHOLINE GROUP-CONTAINING COMPOUND, SURFACE-MODIFYING AGENT, AND A METHOD OF MODIFYING A SURFACE USING A SURFACE-MODIFYING AGENT - A phosphorylcholine group-containing compound that is a structure having a phosphorylcholine group represented by the following formula 1 and an amino group or a group derived from an amino group in an identical compound. | 05-06-2010 |
| 20100261926 | SURFACE-MODIFIED NANODIAMOND AND ITS PRODUCING METHOD - A surface-modified nanodiamond includes a base nanodiamond, and at least one polyglycerol-chain-containing group present on at least a surface portion of the base nanodiamond, in which the polyglycerol-chain-containing group is represented by following Formula (1): | 10-14-2010 |
| 20100267980 | CURING ACCELERATOR FOR DEEP-ULTRAVIOLET-TRANSMITTING EPOXY RESIN, DEEP-ULTRAVIOLET-TRANSMITTING EPOXY RESIN COMPOSITION, AND DEEP-ULTRAVIOLET-TRANSMITTING EPOXY RESIN CURED PRODUCT - An object of the present invention is to provide a deep-ultraviolet-transmitting epoxy resin cured product having high heat resistance and high resistance to deep-ultraviolet light, and to provide a curing accelerator and an epoxy resin composition which are used for producing the epoxy resin cured product. The curing accelerator for deep-ultraviolet-transmitting epoxy resins comprises a tetraalkylphosphonium dialkyl phosphate represented by the following general formula (1): | 10-21-2010 |
| 20110046407 | PROCESS FOR PREPARING ALKOXYAMINES RESULTING FROM BETA-PHOSPHORATED NITROXIDES - The invention relates to an improved process for preparing alkoxyamines resulting from β-phosphorated nitroxides corresponding to the formula (I): | 02-24-2011 |
| 20120046489 | PHOSPHORYLCHOLINE GROUP-CONTAINING COMPOUND, METHOD OF MANUFACTURING A PHOSPHORYLCHOLINE GROUP-CONTAINING COMPOUND, SURFACE-MODIFYING AGENT, AND A METHOD OF MODIFYING A SURFACE USING A SURFACE-MODIFYING AGENT - A phosphorylcholine group-containing compound that is a structure having a phosphorylcholine group represented by the following formula 1 and an amino group or a group derived from an amino group in an identical compound. | 02-23-2012 |
| 20120310002 | 1,4,6,10-Tetra-Double Bond Pentadec-Carbon Phosphonate, Preparation Method Thereof, And Preparation Method Of Lycopene Using The Same - 1,4,6,10-tetra-double bond pentadec-carbon phosphonate of formula (4), and preparation method thereof are provided. The preparation method comprises: reacting a pseudo ionone of formula (2) with sulfonium salt to prepare a epoxide of formula (9), and then reacting the epoxide of formula (9) with magnesium bromide to prepare a C-14 aldehyde of formula (3); condensing the C-14 aldehyde of formula (3) with tetra-alkyl methylene diphosphonate to obtain 1,4,6,10-tetra-double bond pentadec-carbon phosphonate of formula (4). Furthermore, the preparation method of lycopene via 1,4,6,10-tetra-double bond pentadec-carbon phosphonate of formula (4) is also provided. The present method has the advantages of short route, easily obtained raw materials, and low cost. | 12-06-2012 |
| 20120330048 | Lycopene Intermediate 1, 3, 6, 10-Tetra-Double Bond Pentadec-Carbon Phosphonate as well as Preparation Method and Use Thereof - The invention relates to a novel important lycopene intermediate 3,7, 11-trimethyl-1,3,6,10-tetraene-dodecyl diethyl phosphonate. A current lycopene intermediate 2,4,6,10-tetra-double bond pentadec-carbon phosphonate is difficult to synthesize. The invention provides a novel intermediate, which has the following synthesis steps of: preparing 2,6,10-trimethyl-3,5,9-undecane triene-1-aldehyde from pseudoionone; preparing 2,6,10-trimethyl-2,5,9-undecane triene-1-aldehyde from the 2,6,10-trimethyl-3, 5,9-undecane triene-1-aldehyde; and subjecting the 2,6,10-trimethyl-2,5,9-undecane triene-1-aldehyde and tetraethyl methylenediphosphonate to condensation reaction to obtain target product. The invention can generate novel intermediate from raw material pseudoionone only by four reactions, thus the reactions are easy to control and great industrial value are achieved. | 12-27-2012 |
| 20140128630 | PHOSPHONIUM SALTS AND METHODS OF THEIR PREPARATION - Methods for preparing phosphonium salts by reacting a primary phosphine or a secondary phosphine with an ester compound selected from the group consisting of: a phosphate triester; a phosphonate diester; a sulfate diester; and a sulfonate ester; to form a phosphonium salt of formula VII | 05-08-2014 |
| 558089000 | Forming the phosphorus ester group | 34 |
| 20140316154 | METHODS FOR THE SYNTHESIS OF SPHINGOMYELINS AND DIHYDROSPHINGOMYELINS - The present invention includes methods for the synthesis of sphingomyelins and dihydrosphingomyelins. The present invention also includes methods for the synthesis of sphingosines and dihydrosphingosines. The present invention further includes methods for the synthesis of ceramides and dihydroceramides. | 10-23-2014 |
| 558090000 | Reactant having halogen attached directly to phosphorus by nonionic bonding | 15 |
| 20100228045 | BIOCOMPATIBLE SUSPENSION STABILIZER FOR DISPERSING INORGANIC NANOPARTICLES INTO AQUEOUS SOLUTION - The present invention relates to a suspension stabilizer for dispersing inorganic nanoparticles into aqueous medium. More particularly, the present invention is directed to a biocompatible suspension stabilizer which comprises phosphoryl domain having an affinity to the surface of an inorganic nanoparticle and poly(ethylene glycol) having an affinity to the aqueous medium, and which is prepared by reacting a biocompatible poly(ethylene glycol)-derivatized polymer with phosphine oxide having a leaving group. | 09-09-2010 |
| 20110196166 | SLURRY PROCESS FOR SYNTHESIS OF BISPHOSPHITES AND SITU USE THEREOF FOR PRODUCING BISPHOSPHITE - The present invention provides a step-wise process for preparation of a bisphosphite. In step (a) the process prepares a phosphoromonochloridite in high yield, by contacting phosphorus trichloride with an aromatic diol in a slurry under reaction conditions and in the presence of a second aromatic diol to produce a mixture comprising the phosphoromonochloridite, the second aromatic diol, and excess PCl3. The slurry comprises less than 5 mole percent of a nitrogen base, and the organic solvent is selected for its low hydrogen chloride solubility. After removing the excess PCl3, a nitrogen base is added to effect condensation of the phosphoromonochloridite with the second aromatic diol to yield the bisphosphite. The invention particularly provides a process for preparing 6,6′-(3,3′,5,5′-tetra-tert-butylbiphenyl-2,2′-diyl)bis(oxy)didibenzo[d,f][1,3,2]dioxaphosphepine by the above route. | 08-11-2011 |
| 20120041222 | PROCESS THE SYNTHESIS OF BETA GLYCEROL PHOSPHATE - The present invention provides methods for the preparation of beta glycerol phosphate and its salts. In particular, the invention provides efficient methods for the synthesis of beta glycerol phosphate of high purity. | 02-16-2012 |
| 558092000 | And reactant having alcoholic or phenolic -XH group, wherein X is chalcogen (and wherein H of -XH may be replaced by substituted or unsubstituted ammonium, or by a Group IA or IIA light metal) | 12 |
| 20120004438 | Low Triphenylphosphate, High Phosphorous Content Isopropyl Phenyl Phosphates With High Ortho Alkylation - The present invention relates to low triphenyl phosphate, high phosphorous content aryl phosphates with high ortho alkylation that are suitable for use as flame retardant compositions, processes for their preparation, and their use as flame retardants. | 01-05-2012 |
| 20130090489 | CATALYTIC PROCESS FOR PHOSPHO-HALOGENATION OF FLUORINATED ALCOHOLS - A process for manufacturing a polyfluroalkanoyl phosphorodichloridate comprising reacting a polyfluoroalkanol having the general formula R | 04-11-2013 |
| 20130090490 | METHOD FOR PRODUCING AROMATIC DIPHOSPHATES - A method for producing an aromatic diphosphate comprising: Step 1 which is a step where a specific aromatic monohydroxy compound having a steric hindrance group at ortho-positions is made to react with phosphorus oxyhalide in the presence of a Lewis acid catalyst and then the unreacted phosphorus oxyhalide is removed under a reduced pressure to give a specific; and Step 2 which is a step where the reaction product obtained in the above step is made to react with a specific aromatic dihydroxy compound in an amount of 0.5 mol to 1 mol of halogen contained in the reaction product in the presence of a Lewis acid catalyst to give a specific aromatic diphosphate. | 04-11-2013 |
| 558095000 | The phosphorus in the reactant is trivalent | 3 |
| 20130090491 | PHENOL-FREE PHOSPHITES DERIVATIVES AND PREPARATION THEREOF - The present invention relates to phenol-free phosphites and preparation thereof. The phenol-free phosphites are obtained by reacting biphenol, and phosphorous derivatives with higher aliphatic alcohol via condensation and trans-esterification. The phenol-free phosphites of the present invention can be used as a heat stabilizer for resin so as to enhance the heat resistance of the resin during processing at high temperatures. | 04-11-2013 |
| 558096000 | Nitrogen containing compound utilized (e.g., pyridine, carbamates, urea, etc., utilized as catalysts, proton acceptors, etc.) | 1 |
| 20140343313 | METHOD FOR MAKING ORGANODIPHOSPHITES FROM PHOSPHOROCHLORIDITES CHARACTERIZED BY MEASURING SIDE-PRODUCT LEVELS TO DETERMINE FURTHER ADDITIONS - Claimed is a process for producing a phosphorus-containing ligand, preferably a diphosphite ligand structure (DLS) such as structure I. The method includes contacting a phosphorochloridite (structure II) with a compound having the structure X—OH (which can be a bisaryl compound), and a tertiary organic amine to provide structure I′ and as preferred embodiment structure I. | 11-20-2014 |
| 558097000 | Trivalent phosphorus converted into pentavalent phosphorus | 1 |
| 20080255381 | BISBIPHENYLACYLPHOSPHINE OXIDE AND PREPARATION METHOD THEREFORE - A bisbiphenylacylphosphine oxide of formula (I) and its preparation method are provided. The formula of —Ar— is | 10-16-2008 |
| 558098000 | And carbon bonded directly to the phosphorus in the phosphorus containing reactant (e.g., methyl phosphonodichloride, etc.) | 1 |
| 20130023688 | PHOSPHORUS-CONTAINING COMPOUNDS WITH POLYMERIC CHAINS, AND METHODS OF MAKING AND USING THE SAME - The present invention relates to novel phosphorus-containing compounds with polymeric chains, and methods of making and using the same. In part, subject compositions containing phosphorus-containing compounds with polymeric chains and a therapeutic agent, and methods of making and using the same, are described. Certain of the subject compositions exhibit reverse thermal gelation. | 01-24-2013 |
| 558099000 | And divalent chalcogen single bonded directly to the phosphorus in the phosphorus containing reactant (e.g., diethyl phosphorochloridate, etc.) | 2 |
| 20120184764 | Process for preparing alkyl phosphates - The present invention relates to a process for preparing tetraalkyl bisphosphates by reacting tetrachlorobisphosphates with alcohols, neutralizing the resultant hydrogen chloride with a base, and isolating the salt formed in the neutralization from the reaction mixture as a solid. | 07-19-2012 |
| 558100000 | Nitrogen containing compound utilized (e.g., pyridine, carbamates, urea, etc., utilized as catalysts, proton acceptors, etc.) | 1 |
| 20130190523 | Process for the Preparation of Oxidized Phospholipids - Novel synthetic routes, which are highly applicable for industrial preparation of therapeutically beneficial oxidized phospholipids are disclosed. Particularly, novel methods for efficiently preparing compounds having a glycerolic backbone and one or more oxidized moieties attached to the glycerolic backbone, which are devoid of column chromatography are disclosed. Further disclosed are novel methods of introducing phosphorous-containing moieties such as phosphate moieties to compounds having glycerolic backbone and intermediates firmed thereby. | 07-25-2013 |
| 558101000 | Nitrogen containing compound utilized (e.g., pyridine, carbamates, urea, etc., utilized as catalysts, proton acceptors, etc.) | 3 |
| 20120130108 | PROCESS FOR THE PREPARATION OF OXIDIZED PHOSPHOLIPIDS - Novel synthetic routes, which are highly applicable for industrial preparation of therapeutically beneficial oxidized phospholipids are disclosed. Particularly, novel methods for efficiently preparing compounds having a glycerolic backbone and one or more oxidized moieties attached to the glycerolic backbone, which are devoid of column chromatography are disclosed. Further disclosed are novel methods of introducing phosphorous-containing moieties such as phosphate moieties to compounds having glycerolic backbone and intermediates formed thereby. | 05-24-2012 |
| 20120172613 | PROCESS FOR MANUFACTURING PHOSPHATE ESTERS FROM PHOSPHORYL CHLORIDE AND MONOALKYL ETHERS OF GLYCOLS OR POLYGLYCOLS - Phosphate ester compounds are prepared by reacting phosphoryl chloride with at least one mono(alkylene glycol) monoether or poly(alkylene glycol) monoether, or a mixture at least one mono(alkylene glycol) monoether or poly(alkylene glycol) monoether and at least one alkylene glycol or polyalkylene glycol, in the presence of at least three moles per mole of phosphoryl chloride of a pyridinyl compound that is devoid of aliphatic nitrogen atoms. | 07-05-2012 |
| 20130158283 | Process for the Preparation of Oxidized Phospholipids - Novel synthetic routes, which are highly applicable for industrial preparation of therapeutically beneficial oxidized phospholipids are disclosed. Particularly, novel methods for efficiently preparing compounds having a glycerolic backbone and one or more oxidized moieties attached to the glycerolic backbone, which are devoid of column chromatography are disclosed. Further disclosed are novel methods of introducing phosphorous-containing moieties such as phosphate moieties to compounds having glycerolic backbone and intermediates formed thereby. | 06-20-2013 |
| 558104000 | Reactant has -XH, wherein X is chalcogen, bonded directly to phosphorus (wherein H of -XH may be replaced by substituted or unsubstituted ammonium, or by a Group IA or IIA light metal) | 9 |
| 20110046408 | GELLED HYDROCARBONS FOR OILFIELD PROCESSES, PHOSPHATE ESTER COMPOUNDS USEFUL IN GELLATION OF HYDROCARBONS AND METHODS FOR PRODUCTION AND USE THEREOF - Phosphate esters useful for gelling hydrocarbons in combination with a metal source are disclosed along with methods of preparation of the phosphate esters. Fouling in oil refinery towers has been attributed due to distillation of impurities present in phosphate esters used to gel hydrocarbons for oil well fracturing. The improved method of preparation of the phosphate ester results in a product that substantially reduces or eliminates volatile phosphorus, which is phosphorus impurities that distill up to 250° C., and increases the high temperature viscosity of the hydrocarbon gels formed using the phosphate esters. | 02-24-2011 |
| 558106000 | And reactant having halogen bonded directly to carbon, which carbon may be single bonded to any element but may be multiple bonded only to carbon | 1 |
| 558107000 | Having -C(=X)-, wherein X is chalcogen, or cyano attached indirectly to the halogen by acyclic nonionic bonding | 1 |
| 20160024126 | CARBONATE PRODRUGS AND METHODS OF USING THE SAME - The present invention provides carbonate prodrugs which comprise a carbonic phosphoric anhydride prodrug moiety attached to the hydroxyl or carboxyl group of a parent drug moiety. The prodrugs may provide improved physicochemical properties over the parent drug. Also provided are methods of treating a disease or condition that is responsive to the parent drug using the carbonate prodrugs, as well as kits and unit dosages. | 01-28-2016 |
| 558108000 | And -C(=X)- containing reactant, wherein X is chalcogen | 2 |
| 20090124822 | PROCESS FOR PREPARING MALATHION FOR PHARMACEUTICAL USE - The present invention provides a process for preparing a highly pure form of malathion having a reduced level of toxic impurities. In addition, the malathion prepared by the process of this invention is storage stable. The level of toxic impurities in the malathion, e.g., isomalathion, O,O,S-trimethyl phosphorodithioate (MeOOSPS), O,O,S-trimethyl phosphorothioate (MeOOSPO), O,S,S-trimethyl phosphorodithioate (MeOSSPO), malaoxon, isomalathion, diethyl fumarate, methyl malathion, dimethyl malathion, O,O-methyl,ethyl-S-(1,2-dicarboethoxy)ethyl-phosphorodithioate are lower than that of any other commercial preparation of malathion that may be used for pharmaceutical purposes. | 05-14-2009 |
| 20130345463 | PROCESS FOR PREPARING MALATHION FOR PHARMACEUTICAL USE - The present invention provides a process for preparing a highly pure form of malathion having a reduced level of toxic impurities. In addition, the malathion prepared by the process of this invention is storage stable. The level of toxic impurities in the malathion, e.g., isomalathion, O,O,S-trimethyl phosphorodithioate (MeOOSPS), O,O,S-trimethyl phosphorothioate (MeOOSPO), O,S,S-trimethyl phosphorodithioate (MeOSSPO), malaoxon, isomalathion, diethyl fumarate, methyl malathion, dimethyl malathion, O,O-methyl,ethyl-S-(1,2-dicarboethoxy)ethyl-phosphorodithioate are lower than that of any other commercial preparation of malathion that may be used for pharmaceutical purposes. | 12-26-2013 |
| 558110000 | And reactant having alcoholic or phenolic -XH group, wherein X is chalcogen (and wherein H of -XH may be replaced by substituted or unsubstituted ammonium, or by a Group IA or IIA light metal) | 5 |
| 20100063311 | OLIGOMERIC PHOSPHONATE COMPOSITIONS, THEIR PREPARATION AND USES - This invention provides oligomeric hydrogen phosphonates represented by the formula (I) where R is an alkyl group having one to about six carbon atoms; R′ is a linear or branched hydrocarbylene group or an oxygen-containing hydrocarbylene group having two to about twenty carbon atoms or a hydrocarbylene group having at least one cycloaliphatic or aromatic ring, where at least one of R′ is a linear or branched hydrocarbylene group or an oxygen-containing hydrocarbylene group and at least one of R′ is a hydrocarbylene group having at least one cycloaliphatic or aromatic ring; and n is a number from 2 to about 20. Also provided are processes for making these oligomeric hydrogen phosphonates, oligomeric organophosphonate compositions, and processes for making these oligomeric organophosphonate compositions. | 03-11-2010 |
| 20110040116 | Method For Producing Alkoxylated Phosphoric Acid Triesters - The invention relates to a method for producing phosphoric acid triesters of formula (I). According to said method, phosphoric acid or a phosphoric acid derivative selected from orthophosphoric acid, tetraphosphoric decaoxide and polyphosphoric acid is reacted with alkoxylated alcohols of formulae (II) R | 02-17-2011 |
| 20110237818 | PROCESS FOR PRODUCTION OF PURIFIED O-(2,6-DICHLORO-4-METHYL-PHENYL) O,O-DIMETHYL PHOSPHOROTHIOATE - A process for producing a purified O—(2,6-dichloro-4-methylphenyl)—O,O-dimethyl phosphorothioate, the process comprising: | 09-29-2011 |
| 20130158284 | Method For Producing Alkoxylated Phosphoric Acid Triesters - The invention relates to a method for producing phosphoric acid triesters of formula (I). According to said method, phosphoric acid or a phosphoric acid derivative selected from orthophosphoric acid, tetraphosphoric decaoxide and polyphosphoric acid is reacted with alkoxylated alcohols of formulae (II) R | 06-20-2013 |
| 20130331594 | Sythesis of P-Chiral Compounds - Shown is the preparation and subsequent elaboration of P-chiral compounds that can be used as a building block for many P-chiral ligands used, for example, in asymmetric catalytic reactions. Specifically, a synthesis is shown for RP(O)(OR*)CH | 12-12-2013 |
| 558112000 | Reactant consists of phosphorus and sulfur (e.g., phosphorus pentasulfide, etc.) | 1 |
| 20100204501 | PROCESS FOR THE PREPARATION OF MALATHION AND ITS INTERMEDIATE - The present invention relates to the improved process for the preparation of highly pure form of S-[1,2-(dicarbethoxy)-ethyl]O,O-dimethyl phosphorodithioate having formula (I). The compound of formula (I) has adopted name “Malathion”. The present invention also relates to the novel process of preparing intermediate O,O-dimethyldithiophosphoric acid of formula (II), which is useful in the preparation of Malathion. The Malathion prepared by the process of this invention is highly storage stable and toxic impurities are much lower than any other commercial preparation available for the pharmaceutical purpose. | 08-12-2010 |
| 558113000 | Reactant consists of phosphorus and oxygen (e.g., phosphorus pentoxide, etc.) | 7 |
| 20120172614 | METHOD FOR THE MANUFACTURE OF DIALKYL PHOSPHITES - A method for the manufacture of dialkyl phosphites by reacting a P—O component containing from 1 to 6 P—O—P bonds in the molecule, with an alcohol and a ketal corresponding to a selected formula, said ketal will not lead to the formation of an enol structure. The level of the ketal is expressed in relation to the level of co-reactants. A preferred ketal is void of any carbon-hydrogen bonds on the α-carbon atom in the ketal structure. | 07-05-2012 |
| 558114000 | And reactant having alcoholic or phenolic -XH group, wherein X is chalcogen (and wherein H of -XH may be replaced by substituted or unsubstituted ammonium, or by a Group IA or IIA light metal) | 6 |
| 20080300418 | Synthesis of Cardiolipin Analogues and Uses Thereof - The invention provides novel synthetic methodologies for preparing cardiolipin, migrated caridiolipin (1,2-positional isomer of cardiolipin) and their analogues having varying fatty acids and/or alkyl chains with varying length and degrees of saturation/unsaturation. The method comprises (a) reacting an optically pure 1,2-O-dialkyl-sn-glycerol or 1,2-O-dialkyl-sn-glycerol with one or more phosphoramidite reagent(s), wherein a phosphite triester is produced; (b) coupling the product of (a) with glycerol, wherein a protected cardiolipin is produced; and (c) deprotecting the protected cardiolipin, such that cardiolipin is prepared. The cardiolipins and analogues thereof, prepared by the present methods, can be incorporated into liposomes, which can also include active agents such as hydrophobic or hydrophilic drugs, antisense nucleotides or diagnostic agents. Such liposomes can be used to treat diseases or can be used in diagnostic and/or analytical assays. | 12-04-2008 |
| 20090187038 | REAGENTS AND METHODS FOR THE BETA-KETO AMIDE SYNTHESIS OF A SYNTHETIC PRECURSOR TO IMMUNOLOGICAL ADJUVANT E6020 - This invention relates to the synthesis for a precursor of E6020, compound 26, via a β-keto amide alcohol intermediate, compound 22. The synthesis reacts compound 22 with compound 25 and the resultant intermediate is oxidized to produce compound 26, the precursor to E6020. Compounds 22 and 25, and their crystalline forms, represent separate embodiments of the invention. The invention also relates to compounds of formulas (3) and (4) and processes for their preparation. | 07-23-2009 |
| 20120130109 | PROCESS FOR THE MANUFACTURE OF DIALKYLPHOSPHITES - A process for the manufacture of dialkyl phosphites is disclosed. In detail, dialkyl phosphites are prepared starting from P | 05-24-2012 |
| 20120190877 | METHOD FOR THE MANUFACTURE OF DIALKYLPHOSPHITES - A method for the manufacture of dialkyl phosphites is disclosed wherein a P—O component containing from 1 to 6 P—O—P bonds in the molecule is reacted with an alcohol and a carboxylic acid ester having from 1 to 6 carbon atoms in the alkyl group and from 5 to 20 carbon atoms in the esterifying alkyl group of the ester. The dialkyl phosphites are formed under simultaneous removal by distillation of the carboxylic acid formed. | 07-26-2012 |
| 20160068554 | SURFACE-TREATED CALCIUM PHOSPHATE PARTICLES SUITABLE FOR ORAL CARE AND DENTAL COMPOSITIONS - Calcium phosphate particles are described comprising a surface treatment wherein the surface treatment comprises at least one sugar alcohol. Also described are various oral care compositions comprising surface treated calcium phosphate particles and methods of surface treating calcium phosphate particles. | 03-10-2016 |
| 20160075634 | METHODS FOR THE SYNTHESIS OF SPHINGOMYELINS AND DIHYDROSPHINGOMYELINS - The present invention includes methods for the synthesis of sphingomyelins and dihydrosphingomyelins. The present invention also includes methods for the synthesis of sphingosines and dihydrosphingosines. The present invention further includes methods for the synthesis of ceramides and dihydroceramides. | 03-17-2016 |
| 558115000 | Trivalent phosphorus converted into pentavalent phosphorus | 1 |
| 20110124900 | DIARYL ALKYLPHOSPHONATES AND METHODS FOR PREPARING SAME - A method for preparing substantially pure optionally substituted diaryl alkylphosphonates from an optionally substituted triarylphosphite and an optionally substituted trialkylphosphite or an optionally substituted alkanol under special reaction conditions is described. | 05-26-2011 |
| 558122000 | Trivalent phosphorus converted into pentavalent phosphorus | 2 |
| 20100179342 | PROCESS FOR MAKING DIHYDROCARBYL HYDROCARBONPHOSPHONATES - This invention provides a process for the preparation of a dihydrocarbyl hydrocarbonphosphonate. The process comprises forming a reaction mixture from components comprising (i) at least one dihydrocarbyl phosphite, (ii) at least one alkali metal hydrocarbyloxide, and (iii) at least one alcohol, so that a dihydrocarbyl hydrocarbonphosphonate is formed. | 07-15-2010 |
| 558124000 | Reactant having halogen bonded directly to carbon (e.g., Arbuzov rearrangement, etc.) | 1 |
| 558125000 | The reactant contains carbon to carbon unsaturation | 1 |
| 20120029224 | PROCESS FOR THE PREPARATION OF HALOGENATED ARYL PHOSPHONATES - A process for preparing halogen-substituted aryl phosphonates represented by formula (I): wherein each Hal independently represents halogen; k is 1 or 2; n is an integer between 1 and 5, inclusive; m is an integer between 1 and 3, inclusive; and R is a straight or branched C1-C5 alkyl group which may be optionally substituted with one or more halogen atoms, which process comprises reacting under heating a compound represented by the following formula: wherein X is a leaving group, with trialkyl phosphite of the formula (RO) | 02-02-2012 |
| 558129000 | Forming or utilizing an -O-O- or -S-S- group | 2 |
| 20120238772 | PROCESS FOR AND INTERMEDIATES IN THE PREPARATION OF CANFOSFAMIDE AND ITS SALTS - A process for and intermediates in the preparation of canfosfamide and its salts. Some of the intermediates have anticancer activity. | 09-20-2012 |
| 20130296598 | ALKYLTHIOPEROXYDITHIOPHOSPHATE LUBRICANT ADDITIVES - Alkylthioperoxydiphosphates having an alkyl group between about 4 and 18 carbons, a decomposition temperature between about 150 and 300° C. and a wear volume between about 0.0025 and 0.0015 mm | 11-07-2013 |
| 558131000 | Converting a phosphorus ester group to a P-XH group, wherein H of -XH may be replaced by substituted or unsubstituted ammonium or by a Group IA or IIA light metal, and wherein X is chalogen and P may be trivalent or pentavalent | 1 |
| 20170233421 | CRYSTAL OF CYCLIC PHOSPHONIC ACID SODIUM SALT AND METHOD FOR MANUFACTURING SAME | 08-17-2017 |
| 558132000 | Forming phosphorus to chalcogen bond | 4 |
| 20120184765 | Process for preparing alkyl phosphates - The present invention relates to a process for preparing tetraalkyl bisphosphates by reacting tetrachlorobisphosphates with alcohols, neutralizing the resultant hydrogen chloride with a base, and isolating the salt formed in the neutralization from the reaction mixture as a solid. | 07-19-2012 |
| 20120184766 | Process for preparing alkyl phosphates - The present invention relates to a process for preparing tetraalkyl bisphosphates by reacting tetrachlorobisphosphates with alcohols, neutralizing the resultant hydrogen chloride with a base, and isolating the desired product from the reaction mixture by extraction. | 07-19-2012 |
| 20140051879 | BIODEGRADABLE PHOSPHOESTER POLYAMINES - Novel biodegradable phosphoester polyamines are disclosed. The biodegradable phosphoester polyamines may be utilized as cross-linkers for sprayable compositions which may be used as tissue adhesives or sealants. | 02-20-2014 |
| 20140303394 | Synthesis of H-Phosphonate Intermediates and Their Use in Preparing the Herbicide Glyphosate - The esterfication of hypophosphorous acid is followed by reaction with another molecule of alcohol under the action of a nickel catalyst to provide a green method for the preparation of H-phosphonate diesters. This method avoids the need for any stoichiometric chlorine unlike those based on phosphorous trichloride. | 10-09-2014 |
| 558134000 | Substituting carbon for halogen, hydrogen, or metal bonded directly to the phosphorus | 1 |
| 558137000 | Reactant having acyclic or alicyclic carbon to carbon unsaturation | 1 |
| 20100121092 | PROCESS FOR PREPARING AN ALKENYLPHOSPHONIC ACID DERIVATIVE - Process for preparing an alkenylphosphonic acid derivative by reacting a phosphonic acid derivative with an alkyne in the presence of a complex catalyst system and a base whose conjugate acid has a pKa in dimethyl sulfoxide (25° C., 1 bar) of at least 6. | 05-13-2010 |
| 558139000 | Forming a -C(=X)NHH or -N=C=O group, wherein X is chalcogen and substitution may be made for hydrogen only | 1 |
| 20100130765 | LYSINE-BASED PRODRUGS OF ASPARTYL PROTEASE INHIBITORS AND PROCESSES FOR THEIR PREPARATION - The present invention provides processes for synthesizing lysine based compounds of the formula; | 05-27-2010 |
| 558142000 | Forming carbon to carbon multiple bond | 1 |
| 20140005434 | INTERMEDIATE OF LYCOPENE AND PREPARATION METHOD OF INTERMEDIATE THEREOF | 01-02-2014 |
| 558144000 | Reactant having halogen or nitrogen attached directly to phosphorus by nonionic bonding | 3 |
| 20100076212 | METHOD FOR THE PURIFICATION OF TRIORGANOPHOSPHITES BY TREATMENT WITH A BASIC ADDITIVE - The invention provides a method for separating one or more triorganophosphite components from a crude phosphite mixture containing acidic hydrolysis products, the method comprising:
| 03-25-2010 |
| 20160145278 | Compound, Manufacturing Method Therefor, and Method for Manufacturing Optically Active alpha-Aminophosphonate Derivative - A method for producing a compound represented by General Formula (1), the method including:
| 05-26-2016 |
| 20160200747 | PHOSPHORUS-CONTAINING COMPOUND AND CURING EPOXY RESIN COMPOSITION CONTAINING SAME | 07-14-2016 |
| 558145000 | Reactant having nitrogen attached indirectly to phosphorus by nonionic bonding | 6 |
| 20090253926 | Lysine-based prodrugs of aspartyl protease inhibitors and processes for their preparation - The present invention provides processes for synthesizing lysine based compounds of the formula; | 10-08-2009 |
| 20090270647 | METHOD FOR PRODUCING ALPHA - AMINO ACID INCLUDING PHOSPHORUS AND PRODUCTION INTERMEDIATES THEREOF - A method for efficiently producing L-2-amino-4-(hydroxymethylphosphinyl)-butanoic acid, useful as a herbicide, by a catalytic asymmetric synthesis reaction with a high asymmetric yield. The method includes a step in which a compound represented by the below formula (1) and a benzylamine are reacted in the presence of dehydrating agent, then the resulting mass is reacted with hydrogen cyanide in the presence of an asymmetric catalyst, followed by acid hydrolysis, further followed by elimination of a protective group. [chemical formula 1] (1) (where, R | 10-29-2009 |
| 20120059183 | PHOSPHORYLCHOLINE GROUP-CONTAINING COMPOUND, METHOD OF MANUFACTURING A PHOSPHORYLCHOLINE GROUP-CONTAINING COMPOUND, SURFACE-MODIFYING AGENT, AND A METHOD OF MODIFYING A SURFACE USING A SURFACE-MODIFYING AGENT - A phosphorylcholine group-containing compound that is a structure having a phosphorylcholine group represented by the following formula 1 and an amino group or a group derived from an amino group in an identical compound. | 03-08-2012 |
| 20130310591 | AMINO GROUP-CONTAINING PHOSPHORYLCHOLINE, AND METHOD FOR PRODUCING SAME - Provided are amino group-containing phosphorylcholine compound and a method for production thereof, that has a highly active amino group efficiently reactive with a wide variety of functional groups and the like under mild conditions, and is capable of introducing a phosphorylcholine-like group to various substrate surfaces to provide functionalities of the group. The amino group-containing phosphorylcholine compound of the present invention is represented by at least one of formulae (1) and (1′), and may be used as a compound, or a material thereof, capable of introducing a phosphorylcholine-like group to the surface of various substrates, such as medical instruments, cosmetics materials, and medicinal substances. | 11-21-2013 |
| 20150368192 | A METHOD OF SYNTHESIZING CREATINE DERIVATIVES - A method of synthesizing (Boc) | 12-24-2015 |
| 20160068555 | METAL UTILIZATION IN SUPPORTED, METAL-CONTAINING CATALYSTS - Generally, the present invention relates to improvements in metal utilization in supported, metal-containing catalysts. For example, the present invention relates to methods for directing and/or controlling metal deposition onto surfaces of porous substrates. The present invention also relates to methods for preparing catalysts in which a first metal is deposited onto a support (e.g., a porous carbon support) to provide one or more regions of a first metal at the surface of the support, and a second metal is deposited at the surface of the one or more regions of the first metal. Generally, the electropositivity of the first metal (e.g., copper or iron) is greater than the electropositivity of the second metal (e.g., a noble metal such as platinum) and the second metal is deposited at the surface of the one or more regions of the first metal by displacement of the first metal. The present invention further relates to treated substrates, catalyst precursor structures and catalysts prepared by these methods. The invention further relates to use of catalysts prepared as detailed herein in catalytic oxidation reactions, such as oxidation of a substrate selected from the group consisting of N-(phosphonomethyl)iminodiacetic acid or a salt thereof, formaldehyde, and/or formic acid. | 03-10-2016 |
| 558146000 | Purification or recovery | 8 |
| 20080275265 | Process for the Preparation of (Aminoalkylamino)Alkyl Halides and Conversion to Amifostine - The present invention relates to processes for the preparation of (ω-aminoalkylamino)alkyl halides, their conversion to S-ω-(ω-aminoalkylamino)alkyl phosphothioates, and purification of the crystalline products of the reaction. The preparation process for the (ω-aminoalkylamino)alkyl halides comprises contacting an appropriate alcohol with a brominating agent in the presence of a sulfone solvent under temperature and pressure conditions suitable to effect salt formation without subsequent premature precipitation. The process is especially useful for converting (ω-aminoalkylamino)ethyl alcohol to amifostine. | 11-06-2008 |
| 20110130586 | RECOVERY OF MULTIPLE COMPOUNDS AND RECYCLABLE WATER FROM THIN STILLAGE - Methods for recovery of recyclable water and/or fermentation co-products from thin stillage process streams. Microbial metabolites and/or plant derivatives and/or plant extractives are removed from thin stillage after which, recyclable water is recovered from the processed thin stillage. Thin stillage is commingled with one or more polar organic solvents to react microbial metabolites and/or plant derivatives and/or plant extractives with the organic solvents. The reacted organic solvents are then separated from the processed thin stillage. Thin stillage may be commingled with an oil to re act with certain organic compounds, after which, the reacted oil is separated from the processed thin stillage is further extracted with one or more polar organic solvents. Alternatively, thin stillage may be first processed with one or more polar organic solvents, and then processed with an oil. Useful organic compounds may recovered from the reacted oil and from the reacted organic solvents. | 06-02-2011 |
| 20130345464 | I-AND II-TYPE CRYSTALS OF L-A-GLYCERYL PHOSPHORYL CHOLINE, AND METHOD FOR PREPARING SAME - The present invention relates to I- and II-type crystals of L-α-glyceryl phosphoryl choline, and to a method for preparing same. More particularly, the present invention relates to noble I- and II-type anhydride crystals of L-α-glyceryl phosphoryl choline, which have a higher purity than conventional liquid L-α-glyceryl phosphoryl choline, and one advantage of which is that formulations and dosages of pharmaceuticals are easily modified, and another advantage of which is that the hygroscopicity of the crystals are much lower than that of conventional polymorphic crystals, providing excellent stability during storage. The present invention also relates to a method for preparing the I- and II-type crystals of L-α-glyceryl phosphoryl choline. | 12-26-2013 |
| 20150065741 | I-AND II-TYPE CRYSTALS OF L-A-GLYCERYL PHOSPHORYL CHOLINE, AND METHOD FOR PREPARING SAME - The present invention relates to I- and II-type crystals of L-α-glyceryl phosphoryl choline, and to a method for preparing same. More particularly, the present invention relates to noble I- and II-type anhydride crystals of L-α-glyceryl phosphoryl choline, which have a higher purity than conventional liquid L-α-glyceryl phosphoryl choline, and one advantage of which is that formulations and dosages of pharmaceuticals are easily modified, and another advantage of which is that the hygroscopicity of the crystals are much lower than that of conventional polymorphic crystals, providing excellent stability during storage. The present invention also relates to a method for preparing the I- and II-type crystals of L-α-glyceryl phosphoryl choline. The I-type crystal of L-α-glyceryl phosphoryl choline is characterized by having an onset temperature of 147° C. and an absorption peak of 150° C. based on differential scanning calorimeter (DSC) analysis, and by having diffraction patterns where 28-diffraction angles are 9.8±0.2°, 12.0±0.2°, 14.3±0.2°, 15.8±0.2°, and 19.6±0.2° based on X-ray diffraction (XRD) analysis. The II-type crystal of L-α-glyceryl phosphoryl choline is characterized by having an onset temperature of 62° C. and an absorption peak of 66° C., and an onset temperature of 141° C. and an absorption peak of 145° C. based on DSC analysis, and having diffraction patterns where 2θ-diffraction angles are 10.3±0.2°, 12.2±0.2°, 13.4±0.2°, 14.8±0.2°, and 20.6±0.2° based on XRD analysis. | 03-05-2015 |
| 558147000 | Of compounds having plural phosphori | 2 |
| 20130225849 | METHOD OF PURIFYING ORGANIC DIPHOSPHITE COMPOUNDS - The present invention relates to a method of purifying organic diphosphite compounds. | 08-29-2013 |
| 20160083406 | EXTRACTION SOLVENT CONTROL FOR REDUCING STABLE EMULSIONS - Disclosed herein are methods for recovering diphosphonite-containing compounds from mixtures comprising organic mononitriles and organic dinitriles, using liquid-liquid extraction. Also disclosed are treatments to enhance extractability of the diphosphonite-containing compounds. | 03-24-2016 |
| 558149000 | Oxidation employed to purify or recover | 1 |
| 20090099383 | Purification of rosuvatatin intermediate by thin film evaporation and chemical method - Provided are processes for the purification of a pure rosuvastatin intermediate by thin film evaporation and chemical method, and conversion of the intermediate to rosuvastatin or salts thereof. | 04-16-2009 |
| 558150000 | Metal containing material utilized or separated | 1 |
| 20110021803 | PURIFICATION AND PREPARATION OF PHOSPHORUS-CONTAINING COMPOUNDS - A phosphorus-containing compound is treated with at least one metal compound prior to fractional distillation to collect a purified fraction containing about 20 ppb or less arsenic. The purified phosphorus-containing compounds are useful for preparing electronic materials for electronic semiconductor manufacturing. Suitable metal compounds include salts, oxides and/or sulfides of iron, copper, nickel, cobalt, or zinc. | 01-27-2011 |
