| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 552200000 | Tetracyclo naphthacene configured ring system having at least one double bond between ring members and having oxygen bonded directly to a carbon of an interior ring which carbon is a member of one ring only | 16 |
| 552202000 | At least six oxygens bonded directly to the tetracyclo ring system | 16 |
| 20100286417 | Crystalline Minocycline Base and Processes for its Preparation - The invention provides crystalline minocycline base. In particular, three crystalline polymorphic forms, designated Form I, Form II and Form III, of minocycline base are provided. These are characterised by XRD and IR data. Processes for preparing the new polymorphic forms are also provided. For example, Form I is prepared by dissolving and/or suspending amorphous minocycline base in an organic solvent chosen from ethers followed by crystallisation from the mixture. | 11-11-2010 |
| 552203000 | Nitrogen and carbonyl or cyano bonded directly to the tetracyclo ring system (e.g., tetracycline, etc.) | 15 |
| 20090131696 | Reducing Tetracycline Resistance in Living Cells - The present invention provides an improved methodology by which therapeutically to overcome resistance to tetracycline in living cells including bacteria, parasites, fungi, and rickettsiae. The methodology employs a blocking agent such as C5 ester derivatives, or 6-deoxy 13-(substituted mercapto) derivatives of tetracycline, in combination with other tetracycline-type antibiotics as a synergistic combination of compositions to be administered simultaneously, sequentially or concurrently. In another embodiment, certain novel compositions are provided which may be administered alone against, for example, a sensitive or resistant strain of gram positive bacteria such as | 05-21-2009 |
| 20110207951 | 7-Iodo Tetracyclines and Related Methods - 7-substituted fused ring tetracycline compounds, methods of treating tetracycline responsive states, and pharmaceutical compositions containing the 7-substituted fused ring tetracycline compounds are described. | 08-25-2011 |
| 552204000 | Carbon double bonded directly to the tetracyclo ring system (e.g., 6 methylene tetracycline, etc.) | 2 |
| 20090156842 | Methods for synthesizing substituted tetracycline compounds - Methods of synthesizing substituted tetracycline compounds are provided. | 06-18-2009 |
| 20110257421 | 7-N-Substituted Phenyl Tetracycline Compounds - 7-substituted tetracycline compounds, methods of treating tetracycline responsive states, and pharmaceutical compositions containing the 7-substituted tetracycline compounds are described. | 10-20-2011 |
| 552205000 | Plural nitrogens bonded directly to the tetracyclo ring system | 9 |
| 20080234504 | Processes for preparation of 9-haloacetamidominocyclines - The present invention provides substantially pure intermediates, 9-haloacetomidominocyclines, and process of preparing them that are useful for the preparation of glycylcyclines, specifically Tigecycline. | 09-25-2008 |
| 20090099376 | TIGECYCLINE AND METHODS OF PREPARING INTERMEDIATES - Methods of preparing and purifying 9-nitrominocycline and 9-aminominocycline and salts thereof used in the process of making tigecycline, are disclosed. In one embodiment, the invention is directed to a method of preparing the compound of formula 1 | 04-16-2009 |
| 20090275766 | PROCESS FOR THE PREPARATION OF TIGECYCLINE IN THE AMORPHOUS FORM - The invention relates to processes for the preparation of tigecycline (I): | 11-05-2009 |
| 20110105772 | CRYSTALLINE FORMS OF TIGECYCLINE HYDROCHLORIDE - The present invention relates to crystalline forms A and B of Tigecycline hydrochloride and to methods for the preparation of the same. Furthermore the present invention relates to the use of crystalline forms A and B of Tigecycline hydrochloride as intermediates for the formulation of an anti-infective medicament. Moreover the present invention relates to pharmaceutical compositions comprising crystalline form A of Tigecycline hydrochloride in an effective amount and to the use of crystalline form A of Tigecycline hydrochloride as anti-infective medicament. | 05-05-2011 |
| 20110112316 | TIGECYCLINE CRYSTALLINE FORMS AND PROCESSES FOR PREPARATION THEREOF - The present invention relates to solid crystalline Tigecycline, and crystalline forms thereof. | 05-12-2011 |
| 20110124893 | ANTIBIOTIC COMPOUNDS - The present invention relates to the new crystalline solid form XI of Tigecycline and a process of preparing the same. Form XI of Tigecycline is particularly suitable for the isolation of Tigecycline in the last step of the synthesis of Tigecycline. Further the present invention relates to a process of preparing amorphous Tigecycline by spray drying form XI or another crystalline form of Tigecycline. | 05-26-2011 |
| 20130030195 | Crystalline Minocycline Base and Processes for its Preparation - The invention provides crystalline minocycline base. In particular, three crystalline polymorphic forms, designated Form I, Form II and Form III, of minocycline base are provided. These are characterised by XRD and IR data. Processes for preparing the new polymorphic forms are also provided. For example, Form I is prepared by dissolving and/or suspending amorphous minocycline base in an organic solvent chosen from ethers followed by crystallisation from the mixture. | 01-31-2013 |
| 20140005420 | Salts and Polymorphs of a Tetracycline Compound | 01-02-2014 |
| 20140107357 | TIGECYCLINE CRYSTALLINE HYDRATE AND PREPARATION METHOD THEREFOR AND USE THEREOF - Provided are a Tigecycline crystalline hydrate, and a preparation method therefor and use thereof. The crystalline hydrate has high stability for storage, and is used for the manufacture of a medicament for treating or preventing the infection of respiratory system, hepatobiliary system, facial features, urogenital system, bone and joint, skin and soft tissue and endocarditis, septicemia, meningitis caused by susceptible strains of Gram-positive or Gram-negative bacteria, anaerobic bacteria, chlamydia, and mycoplasma in human or animal. | 04-17-2014 |
| 552206000 | Processes | 2 |
| 552207000 | Heavy metal or aluminum containing material utilized | 2 |
| 20100160656 | 7-PHENYL-SUBSTITUTED TETRACYCLINE COMPOUNDS - 7-phenyl-substituted tetracycline compounds which are substantially free of positional isomers, methods of treating tetracycline responsive states, and pharmaceutical compositions containing the 7-phenyl-substituted tetracycline compounds are described. 7-substituted tetracycline compounds which are substantially free of positional isomers, methods of treating tetracycline responsive states, and pharmaceutical compositions containing the 7-substituted tetracycline compounds are described. | 06-24-2010 |
| 20110082305 | 7-Phenyl-Substituted Tetracycline Compounds - 7-phenyl-substituted tetracycline compounds, methods of treating tetracycline responsive states, and pharmaceutical compositions containing the 7-phenyl-substituted tetracycline compounds are described. | 04-07-2011 |
