Class / Patent application number | Description | Number of patent applications / Date published |
549424000 | Nitrogen bonded directly to the hetero ring | 8 |
20090112003 | SYNTHESIS OF QUATERNARY SALT COMPOUNDS - The present invention is directed to a process, having a reduced environmental impact, for preparing phenylamino substituted quaternary salt compounds that are CCR2 antagonists. | 04-30-2009 |
20090112004 | SYNTHESIS OF QUATERNARY SALT COMPOUNDS - The present invention is directed to a process, having a reduced environmental impact, for preparing phenylamino substituted quaternary salt compounds that are CCR2 antagonists. | 04-30-2009 |
20110257418 | Process for Preparing Zanamivir and Intermediates for Use in the Process - The present invention provides a process for preparing methyl 5-acetamido-4-amino-6-(1,2,3-triacetoxypropyl)-5,6-dihydro-4H-pyran-2-carboxylate (V), which process comprises reducing methyl 5-acetamido-4-azido-6-(1,2,3-triacetoxypropyl)-5,6-dihydro-4H-pyran-2-carboxylate (IV) in the presence of a reducing agent selected from the group consisting of lithium aluminium hydride, sodium borohydride, zinc/ammonium chloride, zinc-ferric chloride and ferric chloride/sodium iodide. The present invention also provides compounds of formula (VIII) and (IX) which may be used in the synthesis of zanamivir. The present invention also provides processes for preparing compounds (VIII) and (IX) and processes involving their use, including in the synthesis of zanamivir. | 10-20-2011 |
20140073804 | PROCESS FOR THE PREPARATION OF ZANAMIVIR - The present invention provides a process for preparing 5-(acetylamino)-4-[(aminoiminomethyl)amino]-2,6-anhydro-3,4,5-trideoxy-D-glycero-D-galacto-non-enonic acid Formula (I), which process comprises reducing compound of Formula (IV) by Lindlar catalyst in presence of hydrogen to obtain compound of Formula (V). reacting compound of Formula (V) with pyrazole-1H-carboxamidine or its suitable salt to obtain compound of Formula (VIII). hydrolyzing the compound of Formula (VIII) to give compound of Formula (I). The present invention also provides compounds of formula (VIII) which may be used in the synthesis of zanamivir. The present invention also provides process for preparing compound of formula (VIII) and process involving the use of Formula (VIII), including in the synthesis of zanamivir. | 03-13-2014 |
20150376155 | METHOD FOR MANUFACTURING NEURAMINIC ACID DERIVATIVES - A method for manufacturing a compound represented by the following formula (13): | 12-31-2015 |
20160052906 | METHOD FOR MANUFACTURING NEURAMINIC ACID DERIVATIVES - A method for manufacturing a compound represented by the following formula (I): | 02-25-2016 |
20160068501 | 2,3-Fluorinated Glycosides as Neuraminidase Inhibitors and Their Use as Anti-Virals - Compounds having a structure of Formula I and compositions comprising these compounds are provided. Uses of such compounds and compositions are provided for treatment or prophylaxis of viral infection. In particular, compounds and compositions may be for use in the treatment or prophylaxis of viral influenza. | 03-10-2016 |
20160251328 | PROCESS FOR PRODUCING DIHYDRO-2H-PYRAN DERIVATIVES | 09-01-2016 |