| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 549416000 | Chalcogen bonded directly to the hetero ring | 35 |
| 20100094027 | Process for the Preparation of Glycerol Formal - A process for the preparation of glycerol formal, from a paraformaldehyde and crude glycerin in a condensation reaction without the use of a secondary distilling agent for the removal of the water. | 04-15-2010 |
| 20110295024 | PROCESS FOR THE PREPARATION OF 2 SUBSTITUTED TETRAHYDROPYRANOLS - The present invention relates to a process for the preparation of 2-substituted 4-hydroxy-4-methyltetrahydropyrans by reacting 3-methylbut-3-en-1-ol(isoprenol) with the corresponding alkenealdehydes in the presence of a strongly acidic ion exchanger with subsequent hydrogenation. Specifically, the present invention relates to a corresponding process for the preparation of 2-isobutyl-4-hydroxy-4-methyltetrahydropyran by reacting isoprenol with prenal, with subsequent hydrogenation. | 12-01-2011 |
| 20110306779 | Process for the Preparation and Isolation of 2-Substituted Tetrahydropyranols - Process for the preparation of 2-substituted 4-hydroxy-4-methyltetrahydropyrans of the formula (I) | 12-15-2011 |
| 20120059177 | METHOD FOR PRODUCING 2-SUBSTITUTED TETRAHYDROPYRANOLS - The present invention relates to a process for the preparation of 2-substituted 4-hydroxy-4-methyltetrahydropyranols by reacting 3-methylbut-3-en-1-ol (isoprenol) with the corresponding aldehydes in the presence of a strongly acidic cation exchanger. Specifically, the present invention relates to a corresponding process for the preparation of 2-isobutyl-4-hydroxy-4-methyltetrahydropyran by reacting isoprenol with isovaleraldehyde. | 03-08-2012 |
| 20130217900 | CHIRAL INTERMEDIATES USEFUL FOR THE PREPARATION OF HYDROXYPHOSPHINE LIGANDS - A compound of formula (I), wherein R | 08-22-2013 |
| 20130303788 | METHOD OF PRODUCING BIPHENOLIC COMPOUND, NOVEL BIPHENYL COMPOUND AND SYNTHESIS METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION FOR TREATING PARKINSON'S DISEASE - A method of producing honokiol and analogues thereof, and novel intermediates prepared by virtue thereof are disclosed herein. A pharmaceutical composition for treating Parkinson's disease, which contains honokiol and/or the analogues thereof, is also disclosed herein. | 11-14-2013 |
| 20160060238 | METHOD FOR PRODUCING 2-SUBSTITUTED 4-HYDROXY-4-METHYL-TETRAHYDROPYRANS, SAID METHOD USING RECYCLING - The present invention relates to a process for the preparation of 2-substituted 4-hydroxy-4-methyltetrahydropyrans. | 03-03-2016 |
| 20160186094 | PREPARATION OF SURFACTANTS VIA CROSS-METATHESIS - The present invention relates to compositions comprising alkene benzenes or alkene benzene sulfonates or alkylbenzenes or alkylbenzene sulfonates; methods for making alkene benzenes or alkene benzene sulfonates or alkylbenzenes or alkylbenzene sulfonates; where the benzene ring is optionally substituted with one or more groups designated R*, where R* is defined herein. More particularly, the present invention relates to compositions comprising 2-phenyl linear alkene benzenes or 2-phenyl linear alkene benzene sulfonates or 2-phenyl linear alkylbenzenes or 2-phenyl linear alkylbenzene sulfonates; methods for making 2-phenyl alkene benzenes or 2-phenyl alkene benzene sulfonates or 2-phenyl alkylbenzenes or 2-phenyl alkylbenzene sulfonates; where the benzene ring is optionally substituted with one or more groups designated R*, where R* is defined herein. This invention also relates to compositions, methods of making, use of, and articles of manufacture comprising 2-ethoxylated hydroxymethylphenyl linear alkyl benzenes. This invention also relates to compositions, methods of making, use of, and articles of manufacture comprising 2-propoxylated hydroxymethylphenyl linear alkyl benzenes. | 06-30-2016 |
| 549417000 | Plural chalcogens bonded directly to the hetero ring | 9 |
| 20090076289 | Methods of Making Epothilones - The invention provides novel compounds that may be used as intermediates in the preparation of epothilones, epothilone analogs and derivative, as well as new synthetic methods for producing the intermediates and products. | 03-19-2009 |
| 20100004472 | BIOSURFACTANT-CONTAINING SKIN CARE COSMETIC AND SKIN ROUGHNESS-IMPROVING AGENT - The present invention relates to a cosmetic for skin roughness improvement/skin care containing a biosurfactant, particularly MEL-A, MEL-B or MEL-C. | 01-07-2010 |
| 20100305340 | Biocell - Three step process for obtaining a liquid biofuel from cellulose consisting mainly of isomers of methylpyran and methyl tetrahydropyran using N alkyl imidazol chloride as solvent and catalyst - Three step process for obtaining liquid biofuels consisting mainly of isomers of methylpyran and methyl tetrahydropyran from cellulose, hemicelluloses or starch, using in a first step N alkyl imidazol chloride containing a slight excess of hydrochloric acid 37%. This mixture acts as a solvent and catalyst for dissolution and hydrolysis of cellulose and dehydration of glucose to isomers of hydroxymethyl pyranone (HMP). | 12-02-2010 |
| 20110245516 | MALTOL ETHER PROCESSES AND INTERMEDIATES - Novel processes and intermediates are provided according to the general reaction scheme: Formula I, II, III, IV (I), (II), (III), (IV) utilizing a ruthenium catalyst in an oxidative cleavage of the triene 4 whereby an aldehyde may be produced and optionally taken on to a carboxylic acid 5: Formula V (V) | 10-06-2011 |
| 20140039207 | CHEMICAL COMPOUNDS - The present invention features compounds that are prodrugs of HIV integrase inhibitors and therefore are useful in the delivery of compounds for the inhibition of HIV replication, the prevention and/or treatment of infection by HIV, and in the treatment of AIDS and/or ARC. | 02-06-2014 |
| 20140256961 | CHEMICAL COMPOUNDS - The present invention features compounds that are prodrugs of HIV integrase inhibitors and therefore are useful in the delivery of compounds for the inhibition of HIV replication, the prevention and/or treatment of infection by HIV, and in the treatment of AIDS and/or ARC. | 09-11-2014 |
| 20140323746 | ISOLATION OF ANHYDRO SUGAR ALCOHOLS BY SELECTIVE ADSORBENTS - A method is disclosed for recovering anhydrosugar alcohols from a mixture comprising closely related compounds, such as sugar alcohols. In the method the mixture is contacted with an adsorbent, whereby the anhydrosugar alcohols are selectively adsorbed. The anhydrosugar alcohols can be recovered by desorption from the adsorbent, using a desorbing solvent. | 10-30-2014 |
| 20150080588 | FUSED CYCLOPENTYL ANTAGONISTS OF CCR2 - The present invention comprises processes for preparing compounds of Formula (I). | 03-19-2015 |
| 549418000 | Hydroxy bonded directly at the 3-position and oxygen double bonded directly at the 4-position of the hetero ring (H of -OH may be replaced by a substituted or unsubstituted ammonium ion or a Group IA or IIA light metal) | 1 |
| 20100274031 | METHODS FOR THE SYNTHESIS OF AMRUBICIN - Methods for producing amrubicin and structural analogs thereof. The present invention encompasses synthetic pathways for the production of amrubicin (Formula I) and structural analogs thereof. The synthetic pathways of the present invention preferably employ as a starting material an anthracycline compound having the generic Formula II: | 10-28-2010 |
| 549419000 | Nitrogen attached directly or indirectly to the hetero ring by acyclic nonionic bonding | 7 |
| 20100184999 | Methods of performing cycloadditions, reaction mixtures, and methods of performing asymmetric catalytic reactions - Methods of performing cycloadditions are described that include (a) combining a first reactant and a second reactant in a hydrogen bonding solvent to form a reaction mixture; and (b) reacting the first reactant and the second reactant to form a cycloadduct. Methods of performing asymmetric catalytic reactions are also described that include (a) combining a first reactant, a second reactant, and a catalytic amount of a chiral hydrogen-bond donor in a solvent to form a reaction mixture; and (b) reacting the first reactant and the second reactant to form an enantiomeric excess of a reaction product. Reaction mixtures corresponding to these methods are also described. | 07-22-2010 |
| 20120004428 | Tri-Substituted 2-Benzhydryl-5-Benzylamino-Tetrahydro-Pyran-4-OL and 6-Benzhydryl-4-Benzylamino-Tetrahydro-Pyran-3-OL Analogues, and Novel 3,6-Disubstituted Pyran Derivatives - Novel 3,6-disubstituted pyrans, optionally with a further substituent at the 4-position, are monoamine reuptake inhibitors with activity profiles of anti-depressants. | 01-05-2012 |
| 20120232291 | CRYSTALLIZATION OF 4'-EPIDAUNORUBICIN X HCI - 4′-epidaunorubicin hydrochloride is provided in a crystalline form which is stable and readily soluble. A process of producing the crystalline form includes crystallizing 4′-epidaunorubicin hydrochloride in a solvent system including (a) solvent A selected from C | 09-13-2012 |
| 20130085283 | GERANYLGERANYLACETONE DERIVATIVES - Provided herein are geranylgeranylacetone derivatives and methods of using them. | 04-04-2013 |
| 20140058120 | TRI-SUBSTITUTED 2-BENZHYDRYL-5-BENZYLAMINO-TETRAHYDRO-PYRAN-4-OL AND 6-BENZHYDRYL-4-BENZYLAMINO-TETRAHYDRO-PYRAN-3-OL ANALOGUES, AND NOVEL 3,6-DISUBSTITUTED PYRAN DERIVATIVES - Novel 3,6-disubstituted pyrans, optionally with a further substituent at the 4-position, are monoamine reuptake inhibitors with activity profiles of anti-depressants. | 02-27-2014 |
| 20140336396 | N-HYDROXYLSULFONAMIDE DERIVATIVES AS NEW PHYSIOLOGICALLY USEFUL NITROXYL DONORS - The invention relates to N-hydroxysulfonamide derivatives that donate nitroxyl (HNO) under physiological conditions and are useful in treating and/or preventing the onset and/or development of diseases or conditions that are responsive to nitroxyl therapy, including heart failure and ischemia/reperfusion injury. Novel N-hydroxysulfonamide derivatives release NHO at a controlled rate under physiological conditions, and the rate of HNO release is modulated by varying the nature and location of functional groups on the N-hydroxysulfonamide derivatives. | 11-13-2014 |
| 20160137622 | AMINOTETRAHYDROPYRANS AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES - The present invention is directed to novel substituted aminotetrahydropyrans of structural formula I which are inhibitors of the dipeptidyl peptidase-IV enzyme and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly Type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved. | 05-19-2016 |
| 549420000 | Having -C(=X)-, wherein X is chalcogen, attached directly or indirectly to the hetero ring by acyclic nonionic bonding | 2 |
| 20100204491 | METHOD FOR PREPARING PROSTAGLANDIN DERIVATIVE - Disclosed is a method for preparing a prostaglandin derivative of formula (A): | 08-12-2010 |
| 20110319640 | LARGE-SCALE PURIFICATION OF 2-PYRONE-4,6-DICARBOXYLIC ACID - To provide an industrial purification method of PDC obtained by fermentative production. | 12-29-2011 |
| 549421000 | Alicyclic ring bonded directly to the chalcogen | 3 |
| 20100274032 | METHOD FOR PREPARING PROSTAGLANDIN DERIVATIVE - Disclosed is a method for preparing a prostaglandin derivative of formula (A): | 10-28-2010 |
| 20130005995 | METHOD FOR PREPARING A FATTY ACID DERIVATIVE - A method for manufacturing a fatty acid derivative represented by formula (I) is provided: | 01-03-2013 |
| 20150336921 | PROCESSES AND INTERMEDIATES FOR THE PREPARATIONS OF ISOMER FREE PROSTAGLANDINS - Novel processes for the preparation of a compound of Formula I-2 substantially free of the 5,6-trans isomer: | 11-26-2015 |
| 549423000 | Hydroxy or halogen attached directly or indirectly to the hetero ring by acyclic nonionic bonding (H of -OH may be replaced by a substituted or unsubstituted ammonium ion or a Group IA or IIA light metal) | 6 |
| 20100125144 | HYDROGENATION OF ESTERS WITH RU/TETRADENTATE LIGANDS COMPLEXES - The present invention relates to the field of catalytic hydrogenation and, more particularly, to the use of Ru complexes with tetradentate ligands having at least one amino or imino coordinating group and at least one phosphino coordinating group in hydrogenation processes for the reduction of esters or lactones into the corresponding alcohol or diol respectively. | 05-20-2010 |
| 20110319641 | TREPROSTINIL PRODUCTION - The present invention is directed to a novel method for preparing a synthetic intermediate for treprostinil via a stereoselective alkyne addition reaction. Also described are methods of preparing treprostinil comprising the alkyne addition reaction described herein as well as novel intermediates useful for synthesis prostacyclin derivatives, such as treprostinil. | 12-29-2011 |
| 20130172578 | PROCESS FOR PREPARING 1, 6-HEXANEDIOL - Disclosed are processes for preparing 1,6-hexanediol and synthetic intermediates useful in the production of 1,6-hexanediol from renewable biosources. In one embodiment, a process comprises contacting levoglucosenone with hydrogen in the presence of a first hydrogenation catalyst at a first temperature to form product mixture (I); and heating product mixture (I) in the presence of hydrogen and a second hydrogenation catalyst at a second temperature to form product mixture (II) which comprises 1,6-hexanediol. | 07-04-2013 |
| 20140155637 | CHIRAL SYNTHESIS OF N--1-[2,3-DIHYDROXY-PROPYL]CYCLOPROPANESULFONAMIDES - The present invention relates to a novel enantioselective method of preparing (S)- and (R)-enantiomers of N-{3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]-6-5 methoxyphenyl}-1-[2,3-dihydroxy-propyl]cyclopropanesulfonamide, to novel intermediate compounds, and to the use of said novel intermediate compounds for the preparation of said (S)- and (R)-enantiomers of N-{3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]-6-methoxyphenyl}-1-[2,3-dihydroxy-propyl]cyclopropanesulfonamide. | 06-05-2014 |
| 20140213803 | PROCESS FOR THE PREPARATION OF 2 SUBSTITUTED TETRAHYDROPYRANOLS - The present invention relates to a process for the preparation of 2-substituted 4-hydroxy-4-methyltetrahydropyrans by reacting 3-methylbut-3-en-1-ol (isoprenol) with the corresponding alkenealdehydes in the presence of a strongly acidic ion exchanger with subsequent hydrogenation. Specifically, the present invention relates to a corresponding process for the preparation of 2-isobutyl-4-hydroxy-4-methyltetrahydropyran by reacting isoprenol with prenal, with subsequent hydrogenation. | 07-31-2014 |
| 20160068500 | METHOD FOR PRODUCING 2-SUBSTITUTED 4-HYDROXY-4-METHYL-TETRAHYDROPYRANS IN A REACTOR CASCADE - The invention relates to a method for producing 2-substituted 4-hydroxy-4-methyltetrahydropyrans. | 03-10-2016 |
