| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 549313000 | Additional chalcogen bonded directly to the lactone ring | 22 |
| 20090318715 | Method for the Production of D,L-2-Hydroxy-4-Alkylthio Butyric Acid - The present invention relates to a process for preparing compounds of the formula (I) | 12-24-2009 |
| 20100137618 | METHOD FOR SCREENING FOR COMPOUNDS SELECTIVELY INTERACTING WITH RAD9 - Natural and synthetic compounds of Formulae Ia-Ie having a lactone structure, in particular Securolide, have been determined to be effective anti-tumor compounds which target the hrad9 gene and/or protein encoded thereby or complex containing the protein and/or the p53 gene and/or protein. Securolide is cytoselective for mutants of hRad9 based on studies conducted in Rad9 mutant yeast strains. Securolide appears to interact with mutant hRad9 in cancer cells to produce DNA lesions which result in apoptosis. Studies have demonstrated that Securolide is useful for treating proliferation disorders such as melanoma, leukemia, breast cancer, lung cancer, ovarian cancer, colon cancer, esophagus cancer, liver cancer, and lymphatic cancer, and to alleviate pain associated with the cancer. Other compounds effective for the treatment of cancer and optionally pain associated therewith may also be identified using the same assays, for example, by screening for efficacy in assays using Rad9 and/or p53 defective mutant yeasts. | 06-03-2010 |
| 20120226055 | MICROBIAL PRODUCTION OF 3,4-DIHYDROXYBUTYRATE (3,4-DHBA), 2,3- DIHYDROXYBUTYRATE (2,3-DHBA) AND 3-HYDROXYBUTYROLACTONE (3-HBL) - The invention relates to recombinant cells and their use in the production of 3,4-dihydroxybutyrate, 2,3-dihydroxybutyrate and 3-hydroxybutyrolactone. | 09-06-2012 |
| 20130204016 | METHOD FOR PREPARING 2-HYDROXYBUTYROLACTONE - The invention relates to a method for preparing 2-hydroxybutyrolactone (2HBL) from a compound or its salt or its oligomers, said compound fitting formula (I) | 08-08-2013 |
| 20140194632 | Method for Screening for Compounds Selectively Interacting with RAD9 - Natural and synthetic compounds of Formulae Ia-Ie having a lactone structure, in particular Securolide, have been determined to be effective anti-tumor compounds which target the hrad9 gene and/or protein encoded thereby or complex containing the protein and/or the p53 gene and/or protein. Securolide is cytoselective for mutants of hRad9 based on studies conducted in Rad9 mutant yeast strains. Securolide appears to interact with mutant hRad9 in cancer cells to produce DNA lesions which result in apoptosis. Studies have demonstrated that Securolide is useful for treating proliferation disorders such as melanoma, leukemia, breast cancer, lung cancer, ovarian cancer, colon cancer, esophagus cancer, liver cancer, and lymphatic cancer, and to alleviate pain associated with the cancer. Other compounds effective for the treatment of cancer and optionally pain associated therewith may also be identified using the same assays, for example, by screening for efficacy in assays using Rad9 and/or p53 defective mutant yeasts. | 07-10-2014 |
| 20140364629 | MICROBIAL PRODUCTION OF 3,4-DIHYDROXYBUTYRATE (3,4-DHBA), 2,3- DIHYDROXYBUTYRATE (2,3-DHBA) AND 3-HYDROXYBUTYROLACTONE (3-HBL) - The invention relates to recombinant cells and their use in the production of 3,4-dihydroxybutyrate, 2,3-dihydroxybutyrate and 3-hydroxybutyrolactone. | 12-11-2014 |
| 20160152527 | OLIGOMERIZATION OF C4 STREAMS WITH VERY LOW 1 BUTENE CONTENT | 06-02-2016 |
| 20160251308 | Cyclohexenone Compositions and Process for Making Thereof | 09-01-2016 |
| 549314000 | At least two additional chalcogens bonded directly to the lactone ring | 10 |
| 20110275838 | METHOD FOR OBTAINING CINATRINS C3 AND C1 - The present invention relates to a process for obtaining cinatrins C | 11-10-2011 |
| 20150126752 | PROCESS FOR THE PREPARATION OF 2-C-METHYL-D-RIBONIC-GAMMA-LACTONE - Disclosed is a process to prepare a ribonolactone compound of Formula (I): | 05-07-2015 |
| 549315000 | Double bond between ring members of the lactone ring or chalcogen double bonded directly at the 3- or 4-position of the lactone ring (e.g., ascorbic acid, etc.) | 8 |
| 20090149663 | Strontium (M) abscorbate compositions containing same, method for making same and method of using same - A compound of formula (ascorbate) | 06-11-2009 |
| 20100048919 | Method for Preparing Crystalline 3-0-Alkyl-Ascorbic Acid - The present invention relates to a method for preparing 3-O-substituted ascorbic acid derivatives represented by formula 1, in which 5,6-O-isopropylidene ascorbic acid is reacted with a halide in an organic solvent in the presence of the anion exchange resin absorbed with multi-iodine anions and then deprotected. The method of the present invention has an advantage of providing a target compound with high purity and high yield by finishing the reaction within a short period of time at room temperature. | 02-25-2010 |
| 20100056809 | Ascorbic Acid Derivatives - The present invention discloses the ascorbic acid derivatives. The inventive molecules that combine with one or two hydrophilic headgroups connected by a hydrophobic spacer can increase skin penetration. | 03-04-2010 |
| 20100217017 | NOVEL REACTION WITH A GOLD CATALYST - The invention relates to a process for the catalytic conversion of a carbohydrate, an alcohol, an aldehyde or a poly-hydroxy compound in the presence of a catalyst containing gold in a solvent. | 08-26-2010 |
| 20120077992 | DEVICE FOR CARRYING OUT CHEMICAL REACTIONS UNDER HOMOGENOUS AND HETEROGENOUS CONDITIONS - The present invention relates to a device for treatment of material transported through the device comprising at least one porous element consisting of solid, for example metallic, structure which allows cross-flow of the material through the porous element. The invention also relates to various types of uses of the device. A device in accordance with the invention is particularly useful to carry out chemical reactions under homogenous and heterogeneous conditions. Such a device hereinafter also referred as reactor may comprises a tube ( | 03-29-2012 |
| 20140114079 | Method For Selective Functionalization Of Single-Walled Carbon Nanotubes - The present invention relates to a method for selective functionalization of metallic single-walled carbon nanotubes with a diazonium derivative. The present invention also relates to the use of the mixture of metallic single-walled carbon nanotubes selectively functionalized and to the semiconducting single-walled carbon nanotubes obtained by means of the method according to the invention, for producing transistor channels in particular in electronics, electron acceptor materials, in particular in photovoltaic systems, nonlinear infrared photon emitters or absorbers, current-conducting electrodes, flexible transparent electrodes, antistatic coatings, chemical detectors, and solar cells. | 04-24-2014 |
| 20150368681 | Dehydroascorbic Acid Process - Processes to produce dehydroascorbic acid at the time of use are provided, so that this unstable form of vitamin C can be conveniently utilized for dietary purposes. Products produced by these processes are also described. | 12-24-2015 |
| 20190142726 | DAMAGED HAIR IMPROVING AGENTS AND DAMAGED HAIR IMPROVING COSMETICS CONTAINING THE SAME | 05-16-2019 |
| 549318000 | Acyclic -C(=X)-, wherein X is chalcogen, attached directly or indirectly to the lactone ring by nonionic bonding | 3 |
| 20110060147 | Process for preparing 2,4-dioxotetrahydrofuran-3-carboxylates - Process for preparing 2,4-dioxotetrahydrofuran-3-carboxylates of the formula (I) and/or (I′) | 03-10-2011 |
| 20140148604 | PROCESS FOR PREPARING SODIUM SALTS OR POTASSIUM SALTS OF 4-HYDROXY-2-OXO-2,5-DIHYDROFURAN-3-CARBOXYLATE - Process for preparing sodium or potassium salts of 4-hydroxy-2-oxo-2,5-dihydrofuran-3-carboxylic esters, comprising the reaction of a malonic ester with potassium hydroxide to give the corresponding malonic ester potassium salt of the formula (III) | 05-29-2014 |
| 20150126753 | METHOD FOR MANUFACTRURING BETA-(METH)ACRYLOYLOXY-GAMMA-BUTYROLACTONES - The art relates to provision of a method for manufacturing an (meth)acrylic polymerizable monomer that can be used in various applications, such as an optical material, a resist material, a coating material and a laminate material, and provision of a new β-(meth)acryloyloxy-γ-butyrolactone compound by applying the manufacturing method. The method for manufacturing the β-(meth)acryloyloxy-γ-butyrolactone compound is described, in which a (meth)acrylate compound having a carbonyl group and a ketene compound are condensed and isomerized. Further, the manufacturing method is applied to the new β-(meth)acryloyloxy-γ-butyrolactone compound. | 05-07-2015 |
| 549319000 | Plural alkyl groups bonded directly to the same ring carbon of the lactone ring (e.g., pantolactone, etc.) | 1 |
| 20120136164 | NANOSTRUCTURED METALS - The invention relates to a nanoparticulate material comprising long ultrathin metal nanowires, and to processes for making it. The nanoparticulate material may be used as a catalyst and, in the presence of a chiral modifier, can catalyse enantioselective reactions. | 05-31-2012 |
