| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 549214000 | Silicon containing | 56 |
| 20090187031 | Synthetic techniques and intermediates for polyhydroxy dienyl lactones and mimics thereof - Synthetic methods and intermediates useful in the preparation of lactone containing compounds such as discodermolide and compounds which mimic the chemical or biological activity of discodermolide are provided. | 07-23-2009 |
| 20100048917 | PREPARATION OF ALKYL-SUBSTITUTED 2-DEOXY-2-FLUORO-D-RIBOFURANOSYL PYRIMIDINES AND PURINES AND THEIR DERIVATIVES - The present invention provides (i) a process for preparing a 2-deoxy-2-fluoro-2-methyl-D-ribonolactone derivative, (ii) conversion of the lactone to nucleosides with potent anti-HCV activity, and their analogues, and (iii) a method to prepare the anti-HCV nucleosides containing the 2-deoxy-2-fluoro-2-C-methyl-β-D-ribofuranosyl nucleosides from a preformed, preferably naturally-occurring, nucleoside. | 02-25-2010 |
| 20100228038 | PROCESSES FOR THE PRODUCTION OF POLYCYCLIC FUSED RING COMPOUNDS - The present invention provides processes for the production of polycyclic fused ring compounds. The polycyclic fused ring compounds are produced by protecting a polycyclic fused ring polyol with a bridging silicon-based protecting group and attaching a suitable side chain. Novel polycyclic fused ring compounds and intermediate compounds are also described. | 09-09-2010 |
| 20100317875 | PERFLUOROPOLYETHER GROUP-CONTAINING ACRYLATE COMPOUND - The present invention relates to a photo-curable perfluoropolyether group-containing acrylate compound represented by the following formula (1): | 12-16-2010 |
| 20110054191 | NEW METHODS FOR THE PREPARATION OF TAXANES USING CHIRAL AUXILIARIES - A stereoselective synthesis of novel β-lactam dimers as useful precursors for the preparation of paclitaxel, docetaxel, and analogues thereof. More particularly, the new β-lactams are prepared from readily available and enantiomerically pure chiral auxiliaries. The β-lactams are then reacted with a suitably protected taxane to produce diastereomerically enriched side chain-bearing taxanes. Finally, the chiral auxiliary is cleaved and protecting groups are removed to provide the desired taxane. | 03-03-2011 |
| 20110118484 | PROCESS FOR THE FUNCTIONALIZATION OF BIOLOGICAL MOLECULES - The present invention is targeted at a novel coupling method of 1,3-dipolar cycloaddition type which is of particular use for the functionalization of biological molecules, such as, for example, proteins, enzymes or nucleic acids, insofar as it can be carried out in an aqueous medium and at ambient temperature. | 05-19-2011 |
| 20110184190 | COMPOUNDS USEFUL IN THE SYNTHESIS OF HALICHONDRIN B ANALOGS - In general, the invention features compounds useful for the synthesis of analogs of halichondrin B, such as eribulin or pharmaceutically acceptable salts thereof, e.g., eribulin mesylate. Exemplary compounds are of formula (I), (II), or (III): | 07-28-2011 |
| 20110245511 | Intermediates for Hydroxylated Contrast Enhancement Agents - In one aspect, the present invention provides a protected ligand precursor having structure XX | 10-06-2011 |
| 20110245512 | HYDROXYLATED CONTRAST ENHANCEMENT AGENTS - In one aspect, the present invention provides a contrast enhancement agent comprising an iron chelate having structure I and salts thereof | 10-06-2011 |
| 20110301362 | NOVEL LIQUID TETRACARBOXYLIC DIANHYDRIDES AND PROCESS FOR THE PREPARATION THEREOF - The invention relates to a tetracarboxylic dianhydride represented by the following formula (1). | 12-08-2011 |
| 20120016136 | PROCESS FOR THE PREPARATION OF PROSTAGLANDIN DERIVATIVES - The invention concerns a new process for the preparation of prostaglandin derivatives, in particular prostaglandin F | 01-19-2012 |
| 20120029213 | INTERMEDIATES FOR THE PREPARATION OF ANALOGS OF HALICHONDRIN B - Intermediates and methods of their use in the synthesis of analogs of halichondrin B are provided. | 02-02-2012 |
| 20120065409 | METHODS OF MAKING LUBIPROSTONE AND INTERMEDIATES THEREOF - There is provided processes for preparing Lubiprostone and intermediates thereof. Also provided are compounds, including intermediates for preparing Lubiprostone as well compositions comprising Lubiprostone and other compounds, including intermediates for preparing Lubiprostone and other compounds. (I) | 03-15-2012 |
| 20120116098 | SYNTHESIS OF REVERSIBLY PROTECTED SILANES - The present invention discloses a method for synthesizing a reversibly protected organometallic compound which comprises (1) reacting an organometallic compound with a hydroxyl group containing compound to produce a solution containing the reversibly protected organometallic compound and hydrogen chloride; (2) reacting the solution containing the reversibly protected organometallic compound and the hydrogen chloride with a trialkyl amine to precipitate the hydrogen chloride from the solution; and (3) recovering the reversibly protected organometallic compound from the solution of the reversibly protected organometallic compound. | 05-10-2012 |
| 20120123135 | Method And Materials For Reverse Patterning - A silsesquioxane resin is applied on top of the patterned photo-resist and cured to produce a cured silsesquioxane resin on top of the pattern surface. Subsequently, an aqueous base stripper or a reactive ion etch recipe containing CF | 05-17-2012 |
| 20120232289 | FIVE-MEMBERED CYCLOCARBONATE POLYSILOXANE COMPOUND AND PROCESS FOR PREPARATION OF SAME - A 5-membered cyclic carbonate polysiloxane compound is represented by the below-described formula (1), and is produced by a process that reacts an epoxy-modified polysiloxane compound with carbon dioxide. | 09-13-2012 |
| 20120283450 | COMPOUNDS INCLUDING AN ANTI-INFLAMMATORY PHARMACORE AND METHODS OF USE - This invention provides novel compounds comprising the following anti-inflammatory pharmacore: | 11-08-2012 |
| 20120309988 | INTERMEDIATES FOR THE PREPARATION OF ANALOGS OF HALICHONDRIN B - Intermediates and methods of their use in the synthesis of anslogs of halichondrin B are provided. | 12-06-2012 |
| 20130053581 | INTERMEDIATES FOR THE SYNTHESIS OF BENZINDENE PROSTAGLANDINS AND PREPARATIONS THEREOF - Novel processes for preparing optically active cyclopentanones 1 | 02-28-2013 |
| 20130197244 | METHODS AND COMPOUNDS USEFUL IN THE SYNTHESIS OF FUSED AMINODIHYDROTHIAZINE DERIVATIVES - Provided are compounds and methods useful for the preparation of compounds useful as inhibitors of beta-site amyloid precursor protein (APP)-cleaving enzyme. | 08-01-2013 |
| 20130204014 | SEPARATING AGENT FOR CHROMATOGRAPHY - A separating agent for chromatography is provided that is useful for the separation of specific compounds, e.g., for the optical resolution of amino acids. This separating agent for chromatography provides a higher productivity and contains a crown ether-like cyclic structure and optically active binaphthyl. This separating agent for chromatography containing a crown ether-like cyclic structure and optically active binaphthyl is provided by introducing a substitution group for binding to carrier into a specific commercially available 1,1′-binaphthyl derivative that has substituents at the 2, 2′, 3, and 3′ positions, then introducing a crown ether-like cyclic structure, and subsequently chemically bonding the binaphthyl derivative to the carrier through the substitution group for binding to carrier. | 08-08-2013 |
| 20130296578 | SURFACE-MODIFIED SILICA POWDER AND METHOD FOR PRODUCING THE SAME, AS WELL AS TONER COMPOSITION FOR ELECTROPHOTOGRAPHY - Provided by the present invention is a surface-modified silica powder, characterized in that the said powder is obtained by surface treatment of a silica powder with one or two or more of a compound (A) and with an aminosilane (B), wherein the fixing rate of the compound (A) and the aminosilane (B) is a total of 50% or more, the hydrophobic rate is 80% or more, and the triboelectrostatic charge amount is 200 μC/g or less in its absolute value. The surface-modified silica powder of the present invention can stabilize many properties including fluidity and electrostatic properties while can significantly reduce problems such as fogging and decrease in image quality without significantly deteriorating characteristics of a developing agent and so forth when this is used as an external additive. | 11-07-2013 |
| 20140051868 | Methods and Systems For Synthesis of Ultrabright Silica Particles Capable of Measuring Temperature - Ultrabright fluorescent silica particles that can take stable temperature measurements, and methods of their manufacture. The particles have encapsulated fluorescent substances, some of which can exhibit altering fluorescent characteristics depending on temperature. The particles function as a thermometer allowing one to measure the temperature of the environment. A ratio of the fluorescent peaks in the fluorescent spectrum of each particle depends on temperature, but is dependent on neither the amount of exciting light nor the size of the particles. Further, the particle size can be confined to the range of 8 nm to 100 μm. | 02-20-2014 |
| 20140058119 | PROCESS FOR THE PREPARATION CABAZITAXEL - The present invention discloses a process for the preparation of 4-acetoxy-2α-benzoyloxy-5β,20-epoxy-1-hydroxy-7β,10β-dimethoxy-9-oxotax-11-en-13α-yl(2R,3S)-3-tert-butoxycarbonylamino-2-hydroxy-3-phenyl-propionate Cabazitaxel (I). | 02-27-2014 |
| 20140088314 | BIFUNCTIONAL CHELATING AGENTS - A chelating agent, a metal-chelate, and a contrast agent are provided, wherein the chelating agent comprises a compound of structure (I) | 03-27-2014 |
| 20140155634 | EPOXIDATION CATALYSTS - The present invention generally relates to methods for the synthesis of catalysts, including epoxidation catalysts, and related compounds and catalyst compositions. Embodiments described herein may provide efficient processes for providing catalysts (e.g., epoxidation catalysts) in large quantities and using simplified methods. | 06-05-2014 |
| 20140163242 | INTERMEDIATES FOR THE PREPARATION OF ANALOGS OF HALICHONDRIN B - Intermediates and methods of their use in the synthesis of analogs of halichondrin B are provided. | 06-12-2014 |
| 20140213799 | SYNTHESIS OF REVERSIBLY PROTECTED SILANES - The present invention discloses a method for synthesizing a reversibly protected organometallic compound or a reversibly protected silane. This method can be conducted by (1) reacting an organometallic compound with a hydroxyl group containing compound to produce a solution containing the reversibly protected organometallic compound and hydrogen chloride; (2) reacting the solution containing the reversibly protected organometallic compound and the hydrogen chloride with a trialkyl amine to precipitate the hydrogen chloride from the solution; and (3) recovering the reversibly protected organometallic compound from the solution of the reversibly protected organometallic compound. | 07-31-2014 |
| 20140275572 | SYNTHESIS OF ENT-PROGESTERONE AND INTERMEDIATES THEREOF - The present invention relates to the synthesis of ent-progesterone and intermediates thereof. | 09-18-2014 |
| 20140275573 | METHOD OF PRODUCING BERAPROST - An improved method is described for making single isomers of synthetic benzoprostacyclin analogue compounds, in particular the pharmacologically active 314-d isomer of beraprost. In contrast to the prior art, the method is stereoselective and requires fewer steps than the known methods for making these compounds. | 09-18-2014 |
| 20150031898 | PROCESS FOR PREPARATION OF PROSTAGLANDIN F2 ALPHA ANALOGUES - A convergent synthesis of the prostaglandin F | 01-29-2015 |
| 20150057454 | PROCESS FOR THE PREPARATION OF CABAZITAXEL - The present invention discloses a process for the preparation of 4-acetoxy-2α-benzoyloxy-5β,20-epoxy-1-hydroxy-7β,10β-dimethoxy-9-oxotax-11-en-13α-yl(2 R,35)-3-tert-butoxycarbonylamino-2-hydroxy-3-phenyl-propionate Cabazitaxel (I). | 02-26-2015 |
| 20150291545 | NOVEL METHOD FOR PREPARING CABAZITAXEL FROM 10-DEACETYLBACCATIN III IN HIGH YIELD, AND NOVEL INTERMEDIATE THEREFOR - The present invention relates to a novel method for preparing cabazitaxel from 10-deacetylbaccatin III, and a novel intermediate therefor, and more specifically, to: a method which allows cabazitaxel to be more easily prepared in a high yield and in a high purity within a short time compared with a conventional method by preparing cabazitaxel via a novel intermediate using 10-deacetylbaccatin III as a starting material, and thus is suitable for industrial mass production; and a novel intermediate therefor. | 10-15-2015 |
| 20150361333 | LOADED PARTICLES AND THE METHOD OF PREPARING THEREOF - The present invention relates to fluorescent dye loaded particles and the method of preparing thereof. The method includes steps of preparing the nanoparticles with layered structure having at least one interlayer space, expanding the at least one interlayer space to form at least one expanded interlayer space, introducing the dye molecules to the at least one expanded interlayer space, and covalently bonding the dye molecules with the layered structure. The present invention also relates to a film comprising such nanoparticles. | 12-17-2015 |
| 20160016988 | SYNTHESIS OF ENT-PROGESTERONE AND INTERMEDIATES THEREOF - The present invention relates to the synthesis of ent-progesterone and intermediates thereof. | 01-21-2016 |
| 20160090391 | 3-((2S,5S)-4-METHYLENE-5-(3-OXOPROPYL)TETRAHYDROFURAN-2-YL)PROPANOL DERIVATIVES, THEIR PREPARATION AND INTERMEDIATES USEFUL THEREOF - Discloses is a process for preparation of a compound of formula 11, or a derivative thereof, wherein PG | 03-31-2016 |
| 20160168188 | SYNTHESIS OF ENT-PROGESTERONE AND INTERMEDIATES THEREOF | 06-16-2016 |
| 20160376294 | COMPOUNDS USEFUL IN THE SYNTHESIS OF HALICHONDRIN B ANALOGS - In general, the invention features compounds useful for the synthesis of analogs of halichondrin B, such as eribulin or pharmaceutically acceptable salts thereof, e.g., eribulin mesylate. Exemplary compounds are of formula (I), (II), or (III): | 12-29-2016 |
| 20190144463 | MACROCYCLIZATION REACTIONS AND INTERMEDIATES AND OTHER FRAGMENTS USEFUL IN THE SYNTHESIS OF ANALOGS OF HALICHONDRIN B | 05-16-2019 |
| 549215000 | Oxirane ring containing | 17 |
| 20090012317 | Multi-functional silsesquioxanes for novel coating applications - A multi-functional silsesquioxane, method of making the same, and coatings incorporating the same, including a polyhedral silsesquioxane including at least one first face and at least one second face that is spaced apart from the at least one first face; at least one first functionality bonded to the at least one first face; and at least one second functionality different from the first functionality, and being bonded to the at least one second face. In one particular respect, silica for the silsesquioxane may be derived from rice hull ash via an octa(tetramethylammonium)silsesquioxane octaani{dot over (o)}n. | 01-08-2009 |
| 20090048456 | ACTIVATED SOLID SUPPORT AND METHOD - Disclosed is a method for activating a solid support material with epoxy groups and for immobilising ligands thereon, utilising phase transfer catalytic conditions. The method permits the introduction of epoxy groups and specific nucleophilic ligands on the support material with a high level of substitution. Furthermore, the invention provides a general method for immobilising a ligand for use in a wide variety of chromatographic separation procedures such as ion exchange chromatography, hydrophobic interaction chromatography (HIC), reverse phase chromatography (RPC), or affinity chromatography. | 02-19-2009 |
| 20100160649 | SYSTEM AND PROCESS FOR CONTINUOUS INDUSTRIAL PREPARATION OF 3-GLYCIDYLOXYPROPYLALKOXYSILANES - The present invention relates to a system, to a reactor and to a process for continuous industrial performance of a reaction wherein allyl glycidyl ether A is reacted with an HSi compound B in the presence of a catalyst C and optionally of further assistants, and the system is based at least on the combination of reactants ( | 06-24-2010 |
| 20100191001 | PROCESS FOR CONTROLLED HYDROLYSIS AND CONDENSATION OF EPOXY-FUNCTIONAL ORGANOSILANES AND THE COCONDENSATION THEREOF WITH FURTHER ORGANOFUNCTIONAL ALKOXYSILANES - The present invention relates to a process for performing a controlled hydrolysis and condensation of an epoxy-functional silane of the general formula I R1-SiR′m(OR)3- | 07-29-2010 |
| 20100217016 | LOW VOC EPOXY SILANE OLIGOMER AND COMPOSITIONS CONTAINING SAME - A process for producing a low VOC epoxy silane oligomer which includes hydrolyzing an epoxy silane, the epoxy silane upon hydrolysis of its hydrolyzable sites producing a reduced amount of volatile organic compound compared to that produced by the hydrolysis of a silane possessing an equivalent number of hydrolyzable sites all of which are hydrolyzable alkoxy groups, the hydrolyzing of the epoxy silane being carried out with less than 1.5 equivalents of water, said water being continuously fed during the hydrolysis reaction. | 08-26-2010 |
| 20100274028 | REMOVAL OF POLAR ORGANIC COMPOUNDS AND EXTRANEOUS METALS FROM ORGANOSILANES - The invention relates to a process for treating a composition comprising organosilanes and at least one polar organic compound and/or at least one extraneous metal and/or a compound containing extraneous metal, wherein the composition is contacted with at least one adsorbent and a composition in which the content of the organic polar compound and/or of the extraneous metal and/or of the compound containing extraneous metal is reduced is subsequently obtained, and also to a corresponding composition in which the content of polar organic compounds and/or extraneous metals has been reduced to traces, and to the use of organic resins, activated carbons, silicates and/or zeolites for reducing the amounts of the compounds mentioned. | 10-28-2010 |
| 20100280260 | Holographic storage medium comprising polyfunctional epoxy monomers capable of undergoing cationic polymerization - Disclosed is a holographic recording medium. The novel holographic recording mediums disclosed herein comprises: a) at least one polyfunctional epoxide monomer or oligomer which undergoes acid initiated cationic polymerization. Each epoxide in the monomer or oligomer is linked by group comprising a siloxane to a silicon atom and each monomer or oligomer has an epoxy equivalent weight of greater than about 300 grams/mole epoxide; b) a binder which is capable of supporting cationic polymerization; c) an acid generator capable of producing an acid upon exposure to actinic radiation; and optionally d) a sensitizer. | 11-04-2010 |
| 20100305338 | PROCESS FOR PRODUCING OPTICALLY ACTIVE CIS-SILYL OLEFIN OXIDE COMPOUND - The present invention provides an efficient production method of an optically active cis-silylolefin oxide compound useful as an intermediate for various compounds. A production method of an optically active cis-silylolefin oxide compound by subjecting an optically active cis-silylolefin compound to an asymmetric oxidation with a high enantioselectivity and a high chemical yield by utilizing as a catalyst, an optically active titanium complex of Formula (1), Formula (2): | 12-02-2010 |
| 20110021788 | EPOXY COMPOUND AND PROCESS FOR PRODUCING THE EPOXY COMPOUND - An object of the present invention is to provide an epoxy compound which has a quick curing rate and is excellent in an etching durability and a selectivity and which is liquid at room temperature and a process for producing the above epoxy compound. The epoxy compound of the present application is represented by Formula (I): | 01-27-2011 |
| 20110178313 | POLYSILOXANE COMPOUND AND METHOD OF PRODUCING THE SAME - A polysiloxane represented by the formula (1) or (2): | 07-21-2011 |
| 20110201827 | PROCESS FOR CONTINUOUS PRODUCTION OF OXIDIZED OLEFIN POLYHEDRAL OLIGOMERIC SILSESQUIOXANE CAGES - Methods for continuous bulk production of polyolefin polyhedral oligomeric silsesquioxanes and their amino, isocyanate, and alcohol derivatives using silane coupling agents as precursors. | 08-18-2011 |
| 20130131357 | METHOD FOR PREPARING WHITE CARBON BLACK MODIFIED BY SILANE COUPLING AGENT - The invention relates to a method for preparing silica modified by a silane coupling agent. The method comprises the following steps: preparing a kind of coupling agent sol solution by mixing the solvent, water, catalyst and coupling agent; uniformly dispersing silica into the sol solution by means of ultrasonic dispersion or shear dispersion to achieve a turbid solution with uniform dispersion and ideal particle size; and then stirring the turbid solution at a constant speed to make the coupling agent sol reacting with silica to prepare highly hydrophobic silica modified by the coupling agent through controlling the temperature and reaction time. The coupling agent sol solution is obtained by a sol-gel process and silica is uniformly dispersed in the coupling agent sol solution through combined action of various dynamic means to ensure the sufficient reaction between silica and coupling agent, thus to obtain silica modified by the coupling agent. | 05-23-2013 |
| 20130281713 | BRANCHED SILOXANES AND METHODS FOR SYNTHESIS - The present invention describes branched and functionalized siloxanes and methods for making such compounds. The compounds have a variety of uses. One preferred application is as novel planarizing material for lithography, in which case functionalized branched siloxane, such as an epoxy-modified branched siloxane is particularly useful. | 10-24-2013 |
| 20140046076 | Surface Functionalization of a Substrate in an Ionic Liquid Medium - The present invention relates to a process that is useful for surface functionalization of a substrate comprising at least one hydroxyl function, in which one or more point regions of said surface are brought into contact with an ionic liquid matrix containing at least one reactive molecule, as it is known, that carries at least one reactive function, under conditions that are suitable for the creation of a covalent bond between said reactive function of the molecule and a hydroxyl function of said surface. | 02-13-2014 |
| 20140066636 | NOVEL FLUORENE COMPOUND AND PROCESS FOR PREPARING THE SAME - The present invention relates to an epoxy group-containing novel fluorene compound having a methallyl group at the end thereof represented by the following general formula (1): | 03-06-2014 |
| 20140275574 | PENDANT DIPODAL SILANES HAVING A DISILAPROPYL TERMINUS - Pendant dipodal silanes having formula (I) and methods for their synthesis are provided. In formula (I), R is an organic radical other than methyl and X may be a halogen, an alkoxy group, an acetoxy group, or a dialkylamino group. Films, adhesives, and composites formed from the inventive dipodal silanes generally demonstrate significantly greater hydrolytic resistance and film-forming ability than conventional silanes. | 09-18-2014 |
| 20150299397 | METHOD FOR PREPARING A POLYORGANOSILOXANE AND A POLYORGANOSILOXANE - A polyorganosiloxane resin represented by the following general formula (5): (R | 10-22-2015 |
