Class / Patent application number | Description | Number of patent applications / Date published |
548515000 | The ring nitrogen is bonded directly to two ring carbons of the same cyclo which carbons are members of one cyclo only (e.g., cyclopenta(c)pyrroles, etc.) | 10 |
20090326245 | Novel Polymorphs of Azabicyclohexane - The invention provides polymorphic crystalline forms of acid addition salts of (+)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane designated as polymorph form A, polymorph form B and polymorph form C, where polymorph form A is more thermodynamically stable than the other forms, methods for preparing and using such polymorph forms and pharmaceutical compositions containing such polymorph forms. | 12-31-2009 |
20100036135 | Process for Making Hydroisoindoline Tachykinin Receptor Antagonists - The present invention is directed to a process for preparing certain hydroisoindoline compounds which are useful as neurokinin-1 (NK-1) receptor antagonists, and inhibitors of tachykinin and in particular substance P. The compounds are useful in the treatment of certain disorders, including emesis, urinary incontinence, depression, and anxiety. | 02-11-2010 |
20100280259 | N-Tert-Butoxycarbonyl-2-Pyrrolidinones and Production Method Thereof - N-tert-butoxycarbonyl-2-pyrrolidinones represented by the following formula (1). | 11-04-2010 |
20110034705 | Process For the Synthesis of 3- Amino-3-Cyclobuthylmethyl-2-Hydroxypropionamide or Salts Thereof - A process for preparing 3-amino-3-cyclobutylmethyl-2-hydroxypropionamide of the Formula I: | 02-10-2011 |
20120142940 | Process For The Synthesis Of (+) And (-)-1-(3,4-Dichlorophenyl)-3-Azabicycle[3.1.0]Hexane - The present invention is concerned with novel processes for the preparation of (+)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane or a pharmaceutically acceptable salt thereof, and (−)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane or a pharmaceutically acceptable salt thereof. These compounds have pharmaceutical utility and are known to be useful for treating e.g., depression, anxiety disorders, eating disorders and urinary incontinence. | 06-07-2012 |
20120289709 | Substantially Stereomerically Pure Fused Bicyclic Proline Compounds and Processes for Preparing Boceprevir - The present disclosure provides substantially enantiomerically pure heterobicyclic compounds of the following structural formulas, | 11-15-2012 |
20130345439 | Novel 1-Aryl-3-Azabicyclo[3.1.0]Hexanes: Preparation And Use To Treat Neuropsychiatric Disorders - The invention provides novel, multiply-substituted 1-aryl-3-azabicyclo[3.1.0]hexanes, and related processes and intermediates for preparing these compounds, as well as compositions and methods employing these compounds for the treatment and/or prevention of central nervous system (CNS) disorders, including depression and anxiety. | 12-26-2013 |
20140058116 | PROCESS FOR PREPARING INHIBITORS OF THE HEPATITIS C VIRUS - The present invention relates to synthetic processes useful in the preparation of compounds of Formula (I) that are useful as inhibitors of the hepatitis C virus (HCV) NS3 protease and have application in the treatment of conditions caused by HCV. In particular, the present invention relates to novel oxidation processes useful for preparing compounds of Formula (I) and related compounds, including pharmaceutically acceptable salts, hydrates and solvates thereof, and including stereoisomers thereof. | 02-27-2014 |
20140100374 | SYNTHESIS PROCESS, AND CRYSTALLINE FORM OF 4- BENZAMIDE HYDROCHLORIDE AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT - Industrial synthesis process for the compound of formula (I): | 04-10-2014 |
20140163240 | PROCESS FOR THE SYNTHESIS OF (+) AND (-)-1-(3,4-DICHLOROPHENYL)-3-AZABICYCLO[3.1.0]HEXANE - The present invention is concerned with novel processes for the preparation of (+)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane or a pharmaceutically acceptable salt thereof, and (−)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane or a pharmaceutically acceptable salt thereof. These compounds have pharmaceutical utility and are known to be useful for treating e.g., depression, anxiety disorders, eating disorders and urinary incontinence. | 06-12-2014 |