| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 548484000 | Chalcogen bonded directly to ring carbon of the five-membered hetero ring (e.g., 3-indolols, etc.) | 23 |
| 20110046394 | Pharmaceutical Process and Intermediates 714 - The invention relates to compounds of formula (X), and salts thereof, and their use as intermediates in improved manufacturing processes for the synthesis of pharmaceutical compound (I): | 02-24-2011 |
| 20140066634 | PROCESS FOR PREPARING 6-IODO-2-OXINDOLE - Disclosed is a method for the synthesis of 6-iodo-2-oxindole useful as intermediate in the manufacture of pharmaceutically active ingredients. Also disclosed is a novel intermediate used in the synthesis of this compound. | 03-06-2014 |
| 548485000 | Plural chalcogens bonded directly to ring carbons of the five-membered hetero ring (e.g., isatins, etc.) | 9 |
| 20080200696 | SEPARATION PROCESS USING AROMATIC-SELECTIVE POLYMERIC MEMBRANES - Processes are disclosed for production of value-added products from fluid admixtures of hydrocarbon compounds at least one of which is an aromatic hydrocarbon compound, by means of one or more devices using perm-selective polymeric membranes. More particularly, processes of the invention comprise separations using aromatic-selective polymeric materials comprising long-chain polymeric molecules in which recurring amide and imide linkages are part of the main polymer chain. Processes of the invention advantageously employ aromatic-selective membranes to separate an aromatic enriched stream from gaseous and/or liquid mixtures comprising one or more aromatic hydrocarbon compounds thereby producing a stream comprising the remaining compounds which may include alkenes and/or alkanes containing 3 or more carbon atoms, and/or alicyclic hydrocarbons. Processes of the invention are particularly useful for recovery of meta-xylene and para-xylene products from liquid mixtures even containing ethylbenzene as well as the three xylene isomers. | 08-21-2008 |
| 20090105489 | NOVEL ORGANIC COMPOUND AND METHOD FOR PRODUCING RADIOACTIVE HALOGEN-LABELED ORGANIC COMPOUND USING THE SAME - It is intended to provide a labeling precursor compound used for selectively producing radioactive halogen-substituted syn-1-amino-3-cyclobutane-carboxylic acids, and to provide a process for producing a radioactive halogen-substituted syn-1-amino-3-cyclobutane-carboxylic acid using the labeling precursor compound. A labeling precursor is used in which a phthalimide group is used as a protective group for protecting the amino group. The syn-form of the radioactive halogen-substituted 1-amino-3-cyclobutane-carboxylic acid can be selectively produced by labeling the labeling precursor with a radioactive halogen followed by deprotecting. | 04-23-2009 |
| 20100081828 | CATALYTIC METHOD FOR PRODUCING PHENOLPHTHALEIN COMPOUNDS - A method of producing a phenolphthalein comprises reacting a phenolic compound of the formula: | 04-01-2010 |
| 20100081829 | METHOD FOR PRODUCING PHENOLPHTHALEIN USING A HETEROPOLYACID CATALYST - A method for producing a phenolphthalein compound comprises: reacting a phenolic compound of the formula: | 04-01-2010 |
| 20100087660 | SYNTHESIS OF AMINES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF - The invention relates in a first embodiment to a method for the manufacture of esters of the formula I, | 04-08-2010 |
| 20110112307 | SOLID FORMS COMPRISING (+)-2-[1-(3-ETHOXY-4-METHOXYPHENYL)-2-METHYLSULFONYLETHYL]-4-ACETYLAMINOI- SOINDOLINE-1,3-DIONE, COMPOSITIONS THEREOF, AND USES THEREOF - Solid forms comprising (+)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione, compositions comprising the solid forms, methods of making the solid forms and methods of their use are disclosed. The methods include methods of treating and/or preventing disorders ameliorated by the reduction of levels of TNF-α or the inhibition of PDE4. | 05-12-2011 |
| 20110118478 | PROCESS FOR THE PREPARATION OF OXINDOLES AND ORTHO-SUBSTITUTED ANILINES AND THEIR USE AS INTERMEDIATES FOR SYNTHESES - The present invention relates to processes for the preparation of oxindoles and ortho-substituted anilines and their use as intermediates for syntheses. The invention further relates to a process for the preparation of compounds of formula (4): | 05-19-2011 |
| 20130281711 | PROCESS FOR THE PREPARATION OF OXINDOLES AND ORTHO-SUBSTITUTED ANILINES AND THEIR USE AS INTERMEDIATES FOR SYNTHESES - The present invention relates to processes for the preparation of oxindoles and ortho-substituted anilines and their use as intermediates for syntheses. The invention further relates to a process for the preparation of compounds of formula (4): | 10-24-2013 |
| 20130345438 | 3-SUBSTITUTED-3-HYDROXY OXINDOLE DERIVATIVES AND PROCESS FOR PREPARATION THEREOF - The present invention relates to expedient method for synthesis of 3-substituted-3-hydroxy-oxindole derivatives, which are useful as synthetic precursors to valuable pharmaceutical compounds. These are synthesized by reacting nitromethane with the corresponding isatins of formula (I). The reaction process of isatins was carried using water as a solvent at room temperature to form the corresponding 3-hydroxy-3-nitromethylindolin-2-ones of formula (II). | 12-26-2013 |
| 548486000 | The chalcogen is bonded directly to a ring carbon of the five-membered hetero ring which is adjacent to the ring nitrogen (e.g., 2-indolinones, etc.) | 12 |
| 20080249318 | Process for phenylacetic acid derivatives - A process for the production of a compound of Formula I, or a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable prodrug ester thereof, | 10-09-2008 |
| 20080262244 | Process for the Preparation of Indolone Derivative - A process for the preparation of 4-[2-(Di-n-propylamino)ethyl]-2,3-dihydro-1H-indol-2-one of formula (I) and its pharmaceutically acceptable salts, solvates Formula I involving new intermediates of compound of formula (A) and (B) wherein R represents (i) a halogen atom selected from fluorine, chlorine atom, bromine atom and iodine atom; (ii) lower alkanesulfonyloxy group selected from methanesulfonyloxy, ethanesulfonyloxy, isopropanesulfonyloxy, propanesulfonyloxy, butanesulfonyloxy, tert-butanesulfonyloxy, pentanesulfonyloxy, hexanesulfonyloxy; (iii) substituted or unsubstantiated arylsulfonyloxy group selected from phenylsulfonyloxy, 4-methylphenylsulfonyloxy, 2-methylphenylsulfonyloxy, 4-nitrophenylsulfonyloxy, 4-methoxyphenylsulfonyloxy, 3-chlorophenylsulfonyloxy; (iv) arylalkylsulfonyloxy group selected from benzylsulfonyloxy, 2-phenylethylsulfonyloxy, 4-phenylbutylsulfonyloxy, 4- methylbenzylsulfonyloxy, 2-methylbenzylsulfonyloxy, 4-nitrobenzylsulfonyloxy, 4-methoxybenzylsulfonyloxy, 3-chlorobenzylsulfonyloxy. | 10-23-2008 |
| 20090043111 | Novel process for ropinirole preparation - A method for producing compounds of the formula: | 02-12-2009 |
| 20090275758 | PROCESS FOR PHENYLACETIC ACID DERIVATIVES - A process for the production of a compound of Formula I, or a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable prodrug ester thereof, | 11-05-2009 |
| 20100179332 | PROCESS FOR THE PURIFICATION OF ROPINIROLE HYDROCHLORIDE - The present invention provides an improved process for the purification of ropinirole hydrochloride. The process includes (i) treating ropinirole hydrochloride with sodium dithionate and charcoal in suitable alcoholic solvent; (ii) triturating the ropinirole hydrochloride obtained in step (i) with ethanol; (iii) reacting the triturated solid with base in water immiscible solvent and isolating the free base; and (iv) treating the free base obtained in step (iii) with ethanolic HCl to give ropinirole hydrochloride. | 07-15-2010 |
| 20100249433 | PROCESS FOR THE PURIFICATION OF ROPINIROLE HYDROCHLORIDE - An improved process is described for the purification of ropinirole hydrochloride. The process includes (i) dissolving ropinirole hydrochloride in water; (ii) treating the solution obtained in step (i) with sodium dithionate and charcoal; (iii) treating the filtrate obtained in step (ii) with water immiscible solvent and base and isolating the free base; and (iv) treating the free base obtained in step (iii) with ethanolic HCl to give ropinirole hydrochloride. | 09-30-2010 |
| 20100311985 | INDOLINONE DERIVATIVES AND PROCESS FOR THEIR MANUFACTURE - The present invention relates to specific indolinone derivatives, namely the compounds of formula, in which R | 12-09-2010 |
| 20110046395 | PROCESS FOR THE MANUFACTURE OF A 6-FLUORO-1,2-DIHYDRO-2-OXO-3H-INDOL-3-YLIDENE DERIVATIVE - The present invention relates to a process for the manufacture of the compound 4-[(Z)-[[4-[(dimethylamino)methyl]phenyl]amino](6-fluoro-1,2-dihydro-2-oxo-3H-in-dol-3-ylidene)methyl]-benzenepropanoic acid and to a new intermediate for the synthesis. | 02-24-2011 |
| 20110275832 | Process for Preparing Substituted 1,3-dihydro-2H-indol-2-ones - Process for preparing 1,3-dihydro-2H-indol-2-ones, starting from thioalkyl-, or thiocycloalkyl-substituted indol-2-one compounds, involving
| 11-10-2011 |
| 20120253051 | PROCESS FOR THE PREPARATION OF ROPINIROLE AND SALTS THEREOF - The present invention relates to an improved process for the preparation of Ropinirole and pharmaceutical acceptable salts or derivatives thereof, in particular to a process for large scale production of Ropinirole and salts thereof in high yield and high purity and pharmaceutical preparations containing said compounds. | 10-04-2012 |
| 20150291523 | COMPOUND; TAUTOMER AND GEOMETRIC ISOMER THEREOF; SALT OF SAID COMPOUND, TAUTOMER, OR GEOMETRIC ISOMER; METHOD FOR MANUFACTURING SAID COMPOUND, TAUTOMER, ISOMER, OR SALT; ANTIMICROBIAL AGENT; AND ANTI-INFECTIVE DRUG - The present invention provides compounds belonging to 3-acyloxyindole compounds or 3-acyl-4-hydroxycoumarin compounds, a tautomer or geometric isomer thereof, or a salt thereof and methods for producing the same, which compounds are useful as antibacterial agent and as therapeutic drugs against infectious diseases. | 10-15-2015 |
| 548487000 | Two benzene rings bonded directly to the same ring carbon of the five membered hetero ring | 1 |
| 20080234496 | PROCESS FOR PURIFYING PPPBP - A method for decoloring 2-phenyl-3,3-bis(4-hydroxyphenyl)phthalimidine (“p,p-PPPBP”) is disclosed. The method comprises contacting a liquid solution containing p,p-PPPBP and the common impurities o,p-PPPBP and aminophenone with activated carbon fibers. The activated carbon fibers adsorb the impurities, resulting in a purified solution of p,p-PPPBP. The activated carbon fibers can then be regenerated, such as with a methanol solution having a highly basic pH. | 09-25-2008 |
