| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 548454000 | Additional polycyclo heterocyclic ring system attached directly or indirectly to the bicyclo ring system by nonionic bonding | 21 |
| 20110172442 | AMINO ACID DERIVATIVE - The amino acid derivative of the present invention provides a novel compound that shows excellent analgesic action. The amino acid derivative of the present invention is a novel compound that shows excellent analgesic action to not only a model animal for nociceptive pains but also a model animal for neuropathic pains, so that the amino acid derivative is very useful as a drug for treating various pain diseases. | 07-14-2011 |
| 20130324743 | PROCESS OF PRODUCING CYCLOALKYLCARBOXAMIDO-INDOLE COMPOUNDS - The present invention features processes for preparing compounds, such as (R)-1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide (Compound 1), useful for treating CFTR mediated diseases such as cystic fibrosis. | 12-05-2013 |
| 20160102078 | NOVEL TUBULIN POLYMERIZATION INHIBITOR AND METHOD FOR SYNTHESIZING SAME - The present invention relates to (E)-ethyl 2-(2-methyl-3-((2-(naphtho[2,1-b]furan-2-carbonyl)hydrazono)methyl)-1H-indol-1-yl)acetate as a novel tubulin polymerization inhibitor and a method for synthesizing the same. The compound of the present invention can inhibit mitosis and induce apoptosis and thus be used as an anticancer agent, by binding to tubulin to inhibit microtube polymerization. According to the synthesis method of the present invention, the reaction is simplified and the efficiency is 60%, or higher, leading to a very high yield, thereby providing an effective synthesis method. | 04-14-2016 |
| 20160176820 | AURORA KINASE INHIBITORS | 06-23-2016 |
| 548455000 | The additional polycyclo ring system includes a five-membered nitrogen containing hetero ring | 16 |
| 20080207918 | Cyanine Compounds, Optical Filters, and Optical Recording Materials - A cyanine compound represented by the general formula (I), (VI) or (VII): | 08-28-2008 |
| 20090149662 | PROCESSES FOR PREPARING ZAFIRLUKAST - An improved process for the preparation of substantially pure zafirlukast and pharmaceutical compositions thereof. | 06-11-2009 |
| 20090299076 | Axially asymmetric ester compound and production method thereof - To provide an axially asymmetric optically active biaryl ester compound that can easily produced without the step of optical resolution which was almost indispensable in conventional methods. There is provided a method for producing an axially asymmetric ester compound, comprising a cycloaddition of a compound having a triple bond with the use of a catalyst containing rhodium metal and an optically active bisphosphine. | 12-03-2009 |
| 20100041901 | Sulfonyl Cyanine Dyes and Derivatives - Fluorescent cyanine and squaraine dyes are described that can be conjugated to analyte molecules of interest such as peptides, proteins, nucleic acids, RNA, DNA, carbohydrates, polymers aid small molecules via a sulfonyl or sulfonamide substituent. The new dyes are made via a novel cyanine dye activation procedure that converts the normally stable, water solubilizing sulfonate substituents into a reactive sulfonyl halides. The sulfonyl halides may be directly conjugated to analytes or can be further converted to more stable reactive sulfonamide handles or to water soluble sulfonamides. The general structure of the new dyes is given below where the central linker is an unsaturated carbon chain or an unsaturated chain containing a squaraine moiety. | 02-18-2010 |
| 20100190998 | Alcohols Containing Imide Moieties and Reactive Oligomers Prepared Therefrom - This invention relates to oligomeric compounds that are prepared by the reaction of a dianhydride with an amino-alcohol to yield an imide-diol intermediate, which is then esterified with a carboxylic acid to form a reactive oligomer. An exemplary reaction scheme is the following: | 07-29-2010 |
| 20110230664 | NEW DYE COMPOUNDS - The present disclosure provides compounds that may be used as chromogens, fluorochromes, or as both. Said compounds may further be used as substrate for at least one enzyme, wherein said enzyme is capable of processing an aromatic amine group (—NH | 09-22-2011 |
| 20110263872 | RADIOACTIVE ISOTOPE-LABELED DYE COMPOUND - A radioactive isotope-labeled dye compound represented by the following general formula (I): | 10-27-2011 |
| 20120029206 | DYE-SENSITIZED SOLAR CELL, PHOTOELECTRIC CONVERSION ELEMENT, AND DYE FOR USE IN THE SOLAR CELL AND THE ELEMENT - Provided are a squarylium dye having a carboxyindolenine structure and an N-alkyl substituent, and a photoelectric conversion element having high photoelectric conversion efficiency in a near-infrared region and a dye-sensitized solar cell, both of which are produced using the squarylium dye. The photoelectric conversion element or dye-sensitized solar cell uses a compound represented by the formula (1) as the squarylium dye. In the formula (1), R | 02-02-2012 |
| 20120197026 | COLOR TONE CORRECTING AGENT, SQUARYLIUM COMPOUND AND OPTICAL FILTER - The present invention provides a color tone correcting agent having suitable heat resistance for use in an optical filter, a novel squarylium compound that is specifically preferable as the color tone correcting agent, and an optical filter including the color tone correcting agent. Specifically, the present invention provides a color tone correcting agent including a squarylium compound represented by the general formula (1), a novel squarylium compound which is represented by the general formula (4) and is preferable as the color tone correcting agent, and an optical filter including the color tone correcting agent. The general formula (1) and (4) are each as defined in the specification. | 08-02-2012 |
| 20120296098 | Pentamethine Cyanine Fluorescent Dye with N-substituting at Beta-Position of Conjugated Chain - A pentamethine cyanine fluorescent dye with N-substituting at β-position of conjugated chain is disclosed. The dye reacts with biosubstrate including protein, liposome and DNA, and shows excellent selectivity. It has good living cell membrane permeability and shows good selectivity in living cell staining In addition, the dye has good stability and low background fluorescence, and can be used together with other fluorescent dyes having consistent wavelengths for single-channel excitation and multi-channel detection. The dye can be used in the fields of protein labeling and detecting, fluorescence immunoassay and living cell selective imaging and the like. | 11-22-2012 |
| 20150328340 | METHODS AND COMPOSITIONS FOR ALTERING PHOTOPHYSICAL PROPERTIES OF FLUOROPHORES VIA PROXIMAL QUENCHING - The invention is directed to fluorophore-containing compositions and configurations wherein proximity between the fluorophore and one or more protective agents (PAs) modifies the lifetime of fluorescent and/or dark states, their frequency of occurrence, and the total lifetime of fluorescence in order to appropriately modify the photophysical characteristics of the fluorophore. The invention is also directed to methods that utilize these compositions and configurations. | 11-19-2015 |
| 548457000 | Ring carbon of one of the five-membered hetero rings is bonded directly to ring carbon of the other (e.g., indigo dyes, etc.) | 2 |
| 20140155625 | Modified Naturally-Derived Colorants For Phase Change Ink Applications - A modified naturally-derived colorant comprising a naturally-derived colorant that is modified with an aliphatic quaternary ammonium salt, an aromatic quaternary ammonium salt, or a mixture or combination thereof. The modified naturally-derived colorant is compatible with phase change ink vehicles. | 06-05-2014 |
| 548459000 | Halogen attached directly or indirectly to the bicyclo ring system by nonionic bonding (e.g., dibromoindigo, etc.) | 1 |
| 20160002164 | COMPOUND WITH BRANCHING ALKYL CHAINS, METHOD FOR PREPARING THE SAME, AND USE THEREOF IN PHOTOELECTRIC DEVICE - The invention discloses a compound having branching alkyl chains, the method for preparing the same and use thereof in photoelectric devices. By applying the branching alkyl chains as the solubilizing group to the preparation of organic conjugated molecules (for example, organic conjugated polymers), the number of methylenes between the resultant alky side chains and the backbone, i.e., m>1, which can effectively reduce the effect of the alkyl chains on the backbone π-π stacking, thereby ensuring the solubility of the organic conjugated molecule while greatly increasing the mobility of their carriers. It is suitable for an organic semiconductor material in photoelectric devices such as organic solar cells, organic light emitting diodes and organic field effect transistors, etc. | 01-07-2016 |
| 548460000 | Ring carbon of each of the two five-membered hetero rings is bonded directly to chalcogen or nitrogen (e.g., both rings may be bonded to the same nitrogen atom or to different nitrogen atoms, etc.) | 3 |
| 20140288313 | Semiconducting Compounds and Devices Incorporating Same - Disclosed are molecular and polymeric compounds having desirable properties as semiconducting materials. Such compounds can exhibit desirable electronic properties and possess processing advantages including solution-processability and/or good stability. Organic transistor and photovoltaic devices incorporating the present compounds as the active layer exhibit good device performance. | 09-25-2014 |
| 548461000 | Plural chalcogens bonded directly to ring carbons of each of the two five membered hetero rings (e.g., bisphthalimides, etc.) | 2 |
| 548462000 | The ring nitrogen of each of the two five-membered hetero rings is bonded directly to the same atom or chain, which chain may include a ring (e.g., N,N'-ethylene-bisphthalimide, etc.) | 2 |
| 20120004423 | SYNTHESIS OF OBTAINING MODIFIED POLYETHYLENE GLYCOL INTERMEDIATES - The present invention provides novel and more efficient synthesis's for obtaining an intermediate in the synthesis of obtaining a protecting group aminoxy PEG linker. | 01-05-2012 |
| 20120077988 | BRANCHED HETERO POLYETHYLENE GLYCOL AND INTERMEDIATE - A branched hetero polyethylene glycol according to the present invention is represented by the formula [1]: | 03-29-2012 |
| 548463000 | The additional polycyclo heterocyclic ring system has a lactone ring as one of the cyclos | 1 |
| 20120101284 | METHOD FOR SCREENING INHIBITOR FOR INHIBITING INTERACTION BETWEEN BETA-AMYLOID PEPTIDE AND VEGF AND INHIBITOR SEARCHED BY THE SAME - There is provided a compound found by screening a material for inhibiting a binding between a beta-amyloid 1-42 peptide and VEGF165, in which the inhibition material screened according to the present invention can improve effectiveness as a material for treating Alzheimer's disease. | 04-26-2012 |
