| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 548358100 | Polycyclo ring system having the diazole ring as one of the cyclos | 23 |
| 548358500 | Tetracyclo ring system having the diazole ring as one of the cyclos | 1 |
| 20120101283 | Prostratin and Structural or Functional Analogs Thereof - This invention concerns product and process to convert a hydroxyl group (bold in R | 04-26-2012 |
| 548359100 | Tricyclo ring system having the diazole ring as one of the cyclos | 2 |
| 20100228036 | PROCESS FOR MAKING GLUCOCORTICOID RECEPTOR LIGANDS - The invention encompasses a process for making 2-[1-phenyl-5-hydroxy-4alpha-methyl-hexahydrocyclopenta[f]indazol-5-yl]ethyl phenyl derivatives, which are glucocorticoid receptor ligands, useful for the treatment of inflammatory and immunological diseases. | 09-09-2010 |
| 548359500 | At least three ring hetero atoms in the tricyclo ring system | 1 |
| 20140343294 | PHARMACEUTICAL COMPOUNDS - Compounds of formula (I): | 11-20-2014 |
| 548360100 | Bicyclo ring system having the diazole ring as one of the cyclos (e.g., 2, 4-dichloro-5-nitrophenyl-4,5,6,7-tetrahydro-2H-indazole, etc.) | 20 |
| 20130190509 | HSP90 INHIBITOR AND PREPARATION METHOD AND USE THEREOF - Disclosed are an Hsp90 inhibitor and a preparation method and use thereof. The Hsp90 inhibitor is 2-(4-(3-acetylcarnitineacyloxy)cyclohexylamino)-4-(1-(3,6,6-trimethyl-4-oxy-4,5,6,7-tetrahydroindazole))benzamide. The Hsp90 inhibitor has good water solubility and high bioavailability, and can effectively inhibit the proliferation of cancer cells, such as leukemia, cervical cancer, breast cancer, human laryngeal epithelial carcinoma, or malignant melanoma cells. It can also effectively inhibit the activity of herpes simplex virus. The maximal non-toxic concentration of the Hsp90 inhibitor on normal cells is a high, and the Hsp90 inhibitor only has specific inhibition effect on cancer cells. | 07-25-2013 |
| 548360500 | At least three ring hetero atoms in the bicyclo ring system | 5 |
| 20140107346 | PROCESS FOR PREPARING CHIRAL DIPEPTIDYL PEPTIDASE-IV INHIBITORS - A process for the preparation of pyrazolopyrolidines of structural formula I: and W is or P, wherein in P is an amine protecting group. These compounds are useful in the synthesis of dipeptidyl peptidase-IV inhibitors for the treatment of Type 2 diabetes. Also provided are useful intermediates obtained from the process. | 04-17-2014 |
| 20150099891 | NOVEL CRYSTALLINE FORMS OF A DIPEPTIDYL PEPTIDASE-IV INHIBITORS - Novel crystalline forms of (2R,3S,5R)-2-(2,5-Difluorophenyl)-5-[2-(methylsulfonyl)-2,6-dihydropyrrolo[3,4-c]pyrazol-5(4H)-yl]tetrahydro-2H-pyran-3-amine are potent inhibitors of dipeptidyl peptidase-IV and are useful for the treatment of non-insulin dependent (Type 2) diabetes mellitus. The invention also relates to pharmaceutical compositions containing these novel forms, processes to prepare these forms and their pharmaceutical compositions as well as uses thereof for the treatment of Type 2 diabetes. | 04-09-2015 |
| 20150344487 | AMINOTETRAHYDROPYRANS AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS FOR THE TREATMENT OF DIABETES - The present invention is directed to novel substituted aminotetrahydropyrans of structural formula I which are inhibitors of the dipeptidyl peptidase-IV enzyme and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly Type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved. | 12-03-2015 |
| 20160024100 | PROCESS FOR PREPARING CHIRAL DIPEPTIDYL PEPTIDASE-IV INHIBITORS - A process for the preparation of pyrazolopyrolidines of structural formula I: | 01-28-2016 |
| 20160200727 | PROCESS FOR THE PREPARATION OF KEY INTERMEDIATES OF OMARIGLIPTIN | 07-14-2016 |
| 548361100 | The other ring is a benzene ring | 13 |
| 20100016611 | METHODS FOR MAKING CENTRAL NERVOUS SYSTEM AGENTS THAT ARE TRPV1 ANTAGONISTS - The invention discloses compounds of formula II: | 01-21-2010 |
| 20100056800 | METHOD OF SYNTHESIZING 1H-INDAZOLE COMPOUNDS - A method is provided for synthesizing 1H-indazole compounds in which aromatic carbonyl compounds are reacted with a nitrogen source to form oximes which are then converted to 1H-indazoles. | 03-04-2010 |
| 20110040102 | PROCESS FOR THE PREPARATION OF INDAZOLYL UREAS THAT INHIBIT VANILLOID SUBTYPE 1 (VR1) RECEPTORS - The present invention relates to a process of preparing indazolyl ureas that are useful as antagonists of the vanilloid receptor subtype 1 (VR1). | 02-17-2011 |
| 548361500 | Chalcogen bonded directly to ring carbon of the diazole ring | 1 |
| 20090012308 | PROCESS FOR THE MANUFACTURE OF BENZYLSULFONYLARENES - The present invention provides a process for the manufacture of an arylmethyl-sulfonylarene, R | 01-08-2009 |
| 548362100 | Nitrogen attached directly to the diazole ring by nonionic bonding | 4 |
| 20090105486 | Crystalline Chemotherapeutic - N-(4-(3-Amino-1H-indazol-4-yl)phenyl)-N′-(2-fluoro-5-methylphenyl)urea Tolueneate Crystalline Form 1, ways to make it and ways to use it are disclosed. | 04-23-2009 |
| 20090124815 | Crystalline Chemotherapeutic - N-[4-(3-Amino-1H-indazol-4-yl)phenyl]-N′-(2-fluoro-5-methylphenyl)urea Crystalline Form 1, ways to make it, formulations comprising it and made with it and methods of treating patients having disease using it are disclosed. | 05-14-2009 |
| 20090124816 | Crystalline Chemotherapeutic - N-[4-(3-Amino-1H-indazol-4-yl)phenyl]-N′-(2-fluoro-5-methylphenyl)urea Crystalline Form 2, ways to make it, formulations comprising it and made with it and methods of treating patients having disease using it are disclosed. | 05-14-2009 |
| 20090149659 | 1-ALKYL-3-AMINOINDAZOLES - Methods of making 1-alkylindazoles are described. The methods involve reacting a 2-alkylaminobenzonitrile with a nitrosating agent followed by reduction-cyclization of the resulting nitrosamine to form a 1-alkyl-3-aminoindazole. The 1-alkyl-3-aminoindazole can be deaminated to form a 1-alkylindazole which ultimately can be used to form desired indazoles which are preferably pharmaceutically active products. The process of the present invention further permits the formation of enantiomerically enriched or pure indazoles such as aminoalkyl indazoles. | 06-11-2009 |
| 548362500 | Having chalcogen or nitrogen attached indirectly to the diazole ring by acyclic nonionic bonding | 5 |
| 20090088576 | Process for the Stereoselective Preparation of Alcohols From Alpha, Beta-Insaturated Compounds - A process for the synthesis of an alcohol of formula (I), using as intermediate a compound of formula (V). | 04-02-2009 |
| 20090131681 | Novel fused pyrazolyl compounds having an aminoalkylcarbonyl group - A fused pyrazolyl compound having an anti-tumor potency of the following formula is synthesized: | 05-21-2009 |
| 20120149912 | PROCESS FOR THE PREPARATION OF 1-BENZYL-3-HYDROXYMETHYL-1H-INDAZOLE AND ITS DERIVATIVES AND REQUIRED MAGNESIUM INTERMEDIATES - The present invention relates to the process for the conversion of 1-benzyl-3-hydroxymethyl-1H-indazole according to formula (II), to the 1-benzyl-3-hydroxylmethyl-1H-indazole according to formula (I). | 06-14-2012 |
| 20120184752 | PROCESS FOR THE PREPARATION OF 1-BENZYL-3-HYDROXYMETHYL-1H-INDAZOLE AND ITS DERIVATIVES AND REQUIRED MAGNESIUM INTERMEDIATES - The present invention relates to the process for the preparation of 1-benzyl-3-hydroxymethyl-1H-indazole according ing to formula (II), to be used in a subsequent process for the preparation of 1-benzyl-3-hydroxymethyl-1H-indazole according to formula (I). | 07-19-2012 |
| 20160002210 | INTERMEDIATES FOR USE IN THE PREPARATION OF INDAZOLE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF - Provided herein are novel processes for preparing a compound of Formula (I) to the use of said compound as an intermediate in novel processes for the synthesis of indazole derivatives, and to indazole intermediates and derivatives prepared by the processes described herein. | 01-07-2016 |
| 548363100 | Chalcogen bonded directly to ring carbon of the diazole ring | 1 |
| 20150126747 | ANTI-VIRAL COMPOUNDS - The present invention relates to anti-HCV compounds, compositions comprising the same and methods of using the same to treat HCV infection. | 05-07-2015 |
