| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 548316400 | Chalcogen bonded directly to ring carbon of the diazole ring (e.g., N-vinyl-N, N`ethylene urea, etc.) | 40 |
| 20110178309 | PROCESS FOR PRODUCING ALPHA-HYDROXYKETONE COMPOUND - A process for producing an α-hydroxyketone compound, which comprises subjecting an aldehyde compound to a coupling reaction in the presence of an alkoxyimidazolidine compound represented by the formula (1) wherein R | 07-21-2011 |
| 20110178309 | PROCESS FOR PRODUCING ALPHA-HYDROXYKETONE COMPOUND - A process for producing an α-hydroxyketone compound, which comprises subjecting an aldehyde compound to a coupling reaction in the presence of an alkoxyimidazolidine compound represented by the formula (1) wherein R | 07-21-2011 |
| 548316700 | Additional chalcogen attached directly to ring nitrogen of the diazole ring by nonionic bonding | 2 |
| 20110275829 | Androgen receptor modulating compounds, preparation and uses thereof - The present invention concerns compounds of general formula (I): Method of preparation and uses thereof. | 11-10-2011 |
| 20160251316 | PROCESS FOR THE PREPARATION OF ENZALUTAMIDE | 09-01-2016 |
| 548317100 | Plural chalcogens bonded directly to ring carbons of the diazole ring | 15 |
| 20100010233 | PROCESS FOR PREPARING IMIDAZOLIDIN-2,4-DIONE COMPOUND AND METHOD FOR ACQUIRING SOLID STATE 4,5-DIHYDROXY-2-IMIDAZOLIDINONE COMPOUND - An object of the present invention is to provide an industrially suitable process for preparing an imidazolidin-2,4-dione compound which is safe, simple and easy to prepare the imidazolidin-2,4-dione compound with high yield, which is a useful compound, for example, as a material for decomposing a harmful halogenated aromatic hydrocarbon compound such as dioxin, etc., an electroless silver plating solution for electronic parts, or a diazo copying material, etc. This object can be solved by a process for preparing an imidazolidin-2,4-dione compound which comprises subjecting a 4,5-dihydroxy-2-imidazolidinone compound, (1) to dehydration reaction in the presence of an acid catalyst(s); or (2) to reaction at 100 to 300° C. Or, it can be solved by a process for preparing an imidazolidin-2,4-dione compound which comprises reacting a mixed solution of a urea compound, glyoxal, and a base at 20 to 300° C. | 01-14-2010 |
| 548317500 | Three chalcogens bonded directly to ring carbons of the diazole ring | 1 |
| 20090270634 | NOVEL CRYSTAL FORM OF 5-HYDROXY-1-METHYLHYDANTOIN - Conventional I-form crystals of 5-hydroxy-1-methylhydantoin contain, remaining therein in a considerable amount, the organic solvent used in a purification step. In contrast, in II-form crystals, the amount of the organic solvent remaining therein is smaller than the detection limit. Namely, the II-form crystals contain substantially no residual organic solvent. The novel II-form crystals of 5-hydroxy-1-methylhydantoin obtained through recrystallization from water not only contain substantially no residual organic solvent, but also have a high bulk density and are hence advantageous for pharmaceutical preparation. They further have properties advantageous for production, such as low adhesion. The crystals are significantly useful as a material for medicines required to have high safety, such as drugs for renal insufficiency. | 10-29-2009 |
| 548319100 | Chalcogen attached indirectly to the diazole ring by acyclic nonionic bonding | 3 |
| 20100197934 | PROCESS FOR PRODUCING OPTICALLY ACTIVE ALPHA-METHYLCYSTEINE DERIVATIVE - The present invention provides a simple industrial process for producing an L- or D-optically active α-methylcysteine derivative or its salt, which is a useful pharmaceutical intermediate, from readily available, inexpensive raw materials. In a process for producing an L- or D-optically active α-methylcysteine derivative or its salt, a racemic N-carbamoyl-α-methylcysteine derivative or its salt is D-selectively cyclized with hydantoinase to produce a D-5-methyl-5-thiomethylhydantoin derivative or its salt and an N-carbamoyl-α-methyl-L-cysteine derivative or its salt, which are then subjected to deprotection of the amino group and the sulfur atom, and hydrolysis. | 08-05-2010 |
| 548319500 | The chalcogen, X, is in a -C(=X)- group | 2 |
| 20150057452 | SELECTIVE ANDROGEN RECEPTOR MODULATORS - Compounds having therapeutic potential as androgen receptor modulators, and methods of making such compounds, are provided. The compounds are structurally related to bicalutamide but bear at least one difluoromethyl or C | 02-26-2015 |
| 20150065728 | NOVEL BENZYLIDENE AZOLIDINE DERIVATIVE OR SALT THEREOF - A novel compound which has excellent ultraviolet-absorbing function (especially UVA absorbing function) and excellent hydrophilicity. A benzylidene azolidine derivative represented by structural formula (I) or a salt thereof. In structural formula (I), n represents an integer of 1-5; A | 03-05-2015 |
| 548320500 | Halogen attached directly or indirectly to the diazole ring by acyclic nonionic bonding | 7 |
| 20090259050 | 1,3-Diiodohydantoin compound and production method thereof - The present invention provides a means which can inhibit release of I | 10-15-2009 |
| 20110087031 | 1,3-Diiodohydantoin compound and production method thereof - The present invention provides a means which can inhibit release of I | 04-14-2011 |
| 20110092714 | 1,3-diiodohydantoin compound and production method thereof - The present invention provides a means which can inhibit release of I | 04-21-2011 |
| 20110144350 | 1,3-Diiodohydantoin compound and production method thereof - The present invention provides a means which can inhibit release of I | 06-16-2011 |
| 20150299137 | METHOD AND APPARATUS FOR PRODUCING HALOHYDANTOIN COMPOUND, RECYCLING SYSTEM, AND HALOHYDANTOIN COMPOUND - A method of the present invention for producing a halohydantoin compound by refining, in a dryer ( | 10-22-2015 |
| 20150344438 | METHOD FOR PRODUCING HALOHYDANTOIN COMPOUND AND HALOHYDANTOIN COMPOUND - A method for producing a halohydantoin compound according to the present invention includes the steps of: (a) providing, in a dryer, a composition containing (i) at least one component selected from the group consisting of water, an organic solvent, and elemental halogen and (ii) a halohydantoin compound; and (b) drying the composition under reduced pressure in the dryer, the reduced pressure being reduced to a pressure lower than atmospheric pressure while introducing an inert gas from an outside source into the dryer. | 12-03-2015 |
| 20150376137 | METHOD FOR PRODUCING HALOHYDANTOIN COMPOUND - A production method of the present invention is a method for producing a halohydantoin compound in which method a composition including a halohydantoin compound and an impurity is treated, the method including the step of adding the composition to a mixed solvent of water and an organic solvent and washing the composition. | 12-31-2015 |
| 548321100 | Benzene ring bonded directly to the diazole ring | 3 |
| 20120142937 | METHOD FOR COUPLING HALOGEN-SUBSTITUTED AROMATIC COMPOUNDS WITH ORGANIC COMPOUNDS COMPRISING TRIALKYLSILYL-SUBSTITUTED HETEROATOMS - A process is provided for the preparation of aryl-heteroatom-bridged compounds by reacting a halogen-substituted aromatic compound with a trialkylsilyl-substituted heteroatom-containing organic compound. | 06-07-2012 |
| 20120259127 | PROCESS FOR THE RESOLUTION OF ENANTIOMERS BY PREFERENTIAL EVAPORATIVE CRYSTALLIZATION - A process for the resolution of two enantiomers which involves inducing the preferential crystallization of one enantiomer by adjusting the composition of a suspension or solution including a racemic mixture of the two enantiomers and a solvent, by evaporation of the latter. | 10-11-2012 |
| 20150112082 | DIARYLHYDANTOIN COMPOUNDS - The present invention relates to diarylhydantoin compounds, including diarylthiohydantoins, and methods for synthesizing them and using them in the treatment of hormone refractory prostate cancer. | 04-23-2015 |
| 548322500 | Having -C(=X)-, wherein X is chalcogen, bonded directly to the diazole ring | 7 |
| 20100249431 | PROCESS FOR MANUFACTURING DISULFONIC ACID COMPOUND, ASYMMETRIC MANNICH CATALST, PROCESS FOR MANUFACTURING BETA-AMINOCARBONYL DERIVATIVE, AND NOVEL DISULFONATE - Hexamethylphosphoramide (HMPA) was added to a reaction vessel containing (R)-1,1′-binaphthyl-2,2′-dithiol and potassium hydroxide. The vessel was purged with oxygen and stirred at 80° C. for 5 days under 7 atmospheres of oxygen. After being cooled to room temperature, the reaction product was purified to yield potassium (R)-1,1′-binaphthyl-2,2′-disulfonate. The (R)-1,1′-binaphthyl-2,2′-disulfonic acid obtained from the disulfonate and 2,6-diphenylpyridine were stirred in acetonitrile, and then the solvent was evaporated under reduced pressure. Subsequently, magnesium sulfate and distilled CH | 09-30-2010 |
| 20100261913 | METHOD FOR PRODUCING PRECURSORS FOR L-3,4-DIHYDROXY-6- [18F] FLUOROPHENYL ALAINE AND 2- [18F] FLUORO-L-TYROSINE AND THE ALPHA-METHYLATED DERIVATIVES THEREOF, PRECURSOR, AND METHOD FOR PRODUCING L-3, 4DIHYDROXY-6- [18F] FLUOROPHENYLALANINE AND 2- [18F] FLUORO-L-TYROSINE AND THE ALPHA-METHYLATED DERIVATIVES FROM THE PRECURSOR - Disclosed is a method for producing precursors for L-3,4-dihydroxy-6-[ | 10-14-2010 |
| 20110137046 | PREPARATION METHOD OF (4S,5R)-SEMIESTER - A preparation method of (4S,5R)-semiester in which cycloanhydride conducts enantioselective ring-opening with alcohol in the presence of 9-epiquininurea. With this method, (4S,5R)-semiester is prepared at room temperature with high yield and high stereoselectivity. | 06-09-2011 |
| 548323100 | Acyclic nitrogen bonded directly to the -C(=X)- group | 4 |
| 20140275568 | CRYSTAL OF 5-HYDROXY-1H-IMIDAZOLE-4-CARBOXAMIDE 3/4 HYDRATE, METHOD FOR PRODUCING THE SAME AND CRYSTAL OF 5-HYDROXY-1H-IMIDAZOLE-4-CARBOXAMIDE HYDRATE - Provided is a method for producing 5-hydroxy-1H-imidazole-4-carboxamide.3/4 hydrate, including:
| 09-18-2014 |
| 20150051408 | PACKAGED PRODUCT OF SOLID PREPARATION CONTAINING 5-HYDROXY-1H-IMIDAZOLE-4-CARBOXAMIDE OR SALT THEREOF, OR HYDRATE THEREOF - The present invention provides a packaged product of a solid preparation containing 5-hydroxy-1H-imidazole-4-carboxamide or a salt thereof, or a hydrate thereof, which comprises the solid preparation and an environment-controlling agent packaged together. The packaged product of present invention is useful as a packaged product of a solid preparation containing 5-hydroxy-1H-imidazole-4-carboxamide or a salt thereof, or a hydrate thereof, with which discoloration of the solid preparation is suppressed, and superior storage stability of the solid preparation is obtained. | 02-19-2015 |
| 20150291535 | PACKAGED PRODUCT OF SOLID PREPARATION CONTAINING 5-HYDROXY-1H-IMIDAZOLE-4-CARBOXAMIDE OR SALT THEREOF, OR HYDRATE THEREOF - The present invention provides a packaged product of a solid preparation containing 5-hydroxy-1H-imidazole-4-carboxamide or a salt thereof, or a hydrate thereof, which comprises the solid preparation and an environment-controlling agent packaged together. The packaged product of present invention is useful as a packaged product of a solid preparation containing 5-hydroxy-1H-imidazole-4-carboxamide or a salt thereof, or a hydrate thereof, with which discoloration of the solid preparation is suppressed, and superior storage stability of the solid preparation is obtained. | 10-15-2015 |
| 20150315156 | CRYSTAL OF 5-HYDROXY-1H-IMIDAZOLE-4-CARBOXAMIDE 3/4 HYDRATE, METHOD FOR PRODUCING THE SAME AND CRYSTAL OF 5-HYDROXY-1H-IMIDAZOLE-4-CARBOXAMIDE HYDRATE - Provided is a method for producing 5-hydroxy-1H-imidazole-4-carboxamide.3/4 hydrate, including:
| 11-05-2015 |
| 548323500 | Chalcogen attached indirectly to the diazole ring by acyclic nonionic bonding | 9 |
| 548324100 | The chalcogen, X, is in a -C(=X)- group | 9 |
| 20090093642 | PROCESS FOR THE SYNTHESIS OF L-(+)-ERGOTHIONEINE - This invention relates to a novel process for the preparation of optically pure L-(+)-ergothioneine. The process for the chemical synthesis of L-ergothioneine comprises steps which consist of reacting L-histidine alkyl ester with an acid halide, chloroformate or pyrocarbonate in the presence of a base, hydrolysis of the alkyl-(S,Z)-2,4,5-triamidopent-4-enoate to obtain a (S)-alkyl 2,5-diamido-4-oxopentanoate, acid catalyzed hydrolysis of the (S)-alkyl 2,5-diamido-4-oxopentanoate followed by reaction with a metal thiocyanate to obtain the thiohistidine, protection of the sulfur of thiohistidine as the tert-butyl thioether, dialkylation of the primary amine to obtain a tertiary amine, quaternization of the tertiary amine, and removal of the protecting group to obtain the desired (S)-3-(2-mercapto-1H-imidazol-5-yl)-2-(trialkylammonio)propanoate (I). This process affords a better yield and is capable of practical application at large scale. | 04-09-2009 |
| 20110077411 | PROCESS FOR PREPARING BIPHENYL IMIDAZOLE COMPOUNDS - The invention provides processes for preparing intermediates useful for preparing compounds of the formula: | 03-31-2011 |
| 20120136159 | THE METHOD OF SYNTHESIZING ERGOTHIONEINE AND ANALOGS - The present disclosure relates to a method for synthesizing ergothioneine or one of the derivatives thereof of following formula (I): | 05-31-2012 |
| 20120330029 | METHOD FOR THE SYNTHESIS OF 2-THIOHISTIDINE AND THE LIKE - Methods for the synthesis of 2-thiohistidine or a derivative thereof of the formula (I), or of a physiologically acceptable salt, a tautomer, a stereoisomer or a mixture of stereoisomers in any proportions thereof, from a compound of the formula (II) or a physiologically acceptable salt, a tautomer, a stereoisomer or a mixture of stereoisomers in any proportions thereof, by cleavage reaction in the presence of a thiol at a temperature higher than or equal to 60° C. The invention also relates to compounds of the formula (II) and a method for the synthesis thereof. | 12-27-2012 |
| 20130197237 | MOLECULES HAVING COMBINABLE GROUPS - The present invention relates to nitrogenous associative molecules comprising at least one unit rendering them capable of associating with one another or with a filler, via noncovalent bonds, and comprising a function capable of reacting with a polymer containing unsaturations so as to form a covalent bond with said polymer. | 08-01-2013 |
| 20130345437 | PROCESS FOR PREPARING BIPHENYL IMIDAZOLE COMPOUNDS - The invention provides processes for preparing intermediates useful for preparing compounds of the formula: | 12-26-2013 |
| 20140128615 | Preservation Of Ergothioneine - Compositions comprising ergothioneine and a trimethylamine absorber are provided. Also provided are methods for preventing, reducing or minimizing the fishy, amine odor, due to trimethylamine, that is associated with the processing and/or storage of a preparation containing ergothioneine, by combining with the ergothioneine, during processing or prior to storage, a trimethylamine absorber in an amount sufficient to prevent the detection of any trimethylamine odor by the human nose. A method is further provided for ameliorating the methylamine odor associated with an aqueous ergothioneine-containing preparation after it has developed a fishy trimethylamine odor. | 05-08-2014 |
| 20140364619 | PROCESS FOR THE PREPARATION OF (METH)ACRYLIC ESTERS AND DERIVATIVES - Transesterification processes for producing a compound of formula (I) | 12-11-2014 |
| 20150038725 | PROCESS FOR PREPARING BIPHENYL IMIDAZOLE COMPOUNDS - The invention provides processes for preparing intermediates useful for preparing compounds of the formula: | 02-05-2015 |
| 548324500 | Nitrogen attached indirectly to the diazole ring by acyclic nonionic bonding | 4 |
| 20100305334 | METHOD FOR PREPARING A MATERIAL FORMED FROM ARBORESCENT-BRANCHED MOLECULES COMPRISING ASSOCIATIVE GROUPS - The present invention relates to a method of preparing a material formed from arborescent-branched molecules comprising associative groups that includes the following successive steps: (a) the reaction of at least one at least trifunctional compound (A) bearing first and second functional groups with at least one bifunctional compound (B), the functional groups of which are capable of, reacting with the first functional groups of the compound (A); and (b) the reaction of the compound(s) obtained in step (a) with at least one compound (C) bearing, on the one hand, at least one reactive group capable of reacting with the second functional groups of (A) and; on the other hand, at least one given associative group | 12-02-2010 |
| 20120209008 | PROCESS FOR PREPARING BIPHENYL IMIDAZOLE COMPOUNDS - The invention provides processes for preparing intermediates useful for preparing compounds of the formula: | 08-16-2012 |
| 20130023667 | METHOD FOR PREPARING AMINOETHYL IMIDAZOLIDINONE OR THE THIOCARBONYL THEREOF - The present invention relates to a method for preparing 1-(2-aminoethyl)imidazolidin-2-one or the thiocarbonyl thereof, and also to the product that can be obtained according to this method, and which has a purity of at least 98%, and to the uses thereof. | 01-24-2013 |
| 20130303784 | METHOD FOR PREPARING AMINOETHYL IMIDAZOLIDINONE AND THE THIOCARBONYL THEREOF - The present invention relates to a method for preparing 1-(2-aminoethyl)imidazolidin-2-one or the thiocarbonyl thereof, and also to the product that can be obtained according to this method, and which has a purity of at least 98%, and to the uses thereof. | 11-14-2013 |
| 548325100 | The chalcogen is sulfur or selenium (e.g., 2-mercaptoimidazoline, ethylenethiourea, etc.) | 1 |
| 20120108822 | Process For The Preparation Of Chalcogene Compounds - The present invention is a novel process for the preparation of chalcogenone compounds by conversion of ionic liquids and salts comprising nitrogen-containing heterocyclic cations and basic anions to the corresponding nitrogen-containing heterocyclic chalcogenones by reaction with elemental chalcogens. | 05-03-2012 |
| 548325500 | Benzene ring bonded directly to the diazole ring | 1 |
| 20090209768 | NOVEL IMIDAZOLIDINONE DERIVATIVE, METHOD OF PRODUCING THE SAME AND METHOD OF PRODUCING OPTICALLY ACTIVE AMINO ACID - The objective of the present invention is to provide an optically active imidazolidinone derivative widely usable for synthesizing an optically active amino acid, a method of easily producing the derivative, and a method of easily producing an optically active amino acid by using the derivative. The objective can be achieved by producing an optically active amino acid using a novel optically active imidazolidinone derivative represented by a general formula (3) and the like. According to the method of the present invention, an optically active imidazolidinone derivative can be obtained by preferential crystallization from a mixture of isomers of the imidazolidinone derivative. Therefore, an optically active amino acid can be easily and stereoselectively produced without cumbersome procedures required for the conventional methods, such as resolution of diastereomers, synthesis from an optically active amino acid and resolution of isomers by silica gel column chromatography. | 08-20-2009 |
