| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 548262200 | 1,2,4-triazoles (including hydrogenated) | 78 |
| 20090062550 | Process for the Large Scale Production of Rizatriptan Benzoate - The present invention provides a method for preparing pure Rizatriptan benzoate having purity more than 99.5% and dimer impurity less than 0.1% comprises, i) Condensation of 1,2,4-Triazole with 4-Nitro benzyl bromide to yield 1-(4-nitrophenyl)methyl-1,2,4-triazole ii) Reducing the 1-(4-nitrophenyl)methyl-1,2,4-triazole to give 1-(4-aminophenyl)methyl-1,2,4-triazole iii) Converting 1-(4-aminophenyl)methyl-1,2,4-triazole to 1-(4-hydrazinophenyl)methyl-1,2,4-triazole hydrochloride iv) Condensing the hydrazine derivative with 4-(Dimethylamino) butanal diethylacetal to get Rizatriptan and v) Salification of Rizatriptan to Rizatriptan benzoate. | 03-05-2009 |
| 20090247765 | PROCESS FOR PREPARING PURE ANASTROZOLE - The present invention discloses two new related substances (6) and (7) of Anastrozole synthesis from Q. A. Salt (5) as in Scheme—1 and purification procedures to get Anastrozole (1) free from (6) and (7). | 10-01-2009 |
| 20090270633 | Synthesis of 4-[1-(4-cyano phenyl)-(1,2,4-triazol-1-yl)methyl] benzonitrile and 4-[1-(1H-1,2,4-triazol-1-yl)methylene benzonitrile intermediate - The present invention relates to a process for the preparation of 4-[1-(4-cyano phenyl)-1-(1,2,4-triazol-1-yl)methyl]benzonitrile (letrozole), substantially free from its isomeric impurity. The preparation involves reaction of 4-[1-(1H-1,2,4-triazol-1-yl)methylene benzonitrile with 4-fluorobenzonitrile in the presence of an organic solvent and a silicon amine. The present invention also relates to a process for the preparation of 4-[1-(1H-1,2,4-triazol-1-yl)methylene benzonitrile which involves: (a) the reaction of a 4-halomethyl benzonitrile with 1,2,4-triazole in the presence of cesium carbonate and an organic solvent to obtain a reaction mass comprising 4-[1-(1,2,4-triazole-1-yl)methyl]benzonitrile of formula II; and (b) precipitation of 4-[1-(1,2,4-triazole-1-yl)methyl]benzonitrile (II) from the reaction mass using a suitable organic solvent. | 10-29-2009 |
| 20090286989 | Process for High Purity Anastrozole - The present invention relates to an improved process for the preparation of anastrozole having enhanced purity from crude anastrozole having isomeric impurity content up to less than | 11-19-2009 |
| 20100234617 | PROCESS FOR PREPARATION OF LETROZOLE AND ITS INTERMEDIATES - The present invention relates to an improved process for preparation of the non-steroidal aromatase inhibitor drug, Letrozole of formula (I) and its intermediates, 4-[1-(1,2,4-triazolyl)methyl]-benzonitrile of formula (IV) and 4-[1-(1,2,4-triazolyl)methyl]-benzonitrile hydrochloride of formula (VII), all having a purity of ≧99%, which is simple, convenient, economical, does not use hazardous chemicals and industrially viable. | 09-16-2010 |
| 20110184188 | Insecticidal Benzenedicarboxamide Derivative - The present invention relates to a novel benzenedicarboxamide derivative and the use thereof as an insecticide having the formula (I) wherein the chemical groups W | 07-28-2011 |
| 20130172573 | Process for Preparing Chiral 3-Triazolyl Sulphoxide Derivatives - The present invention relates to a catalytic process for preparing 3-triazolyl sulphoxide derivatives in enantiomerically pure or enantiomerically enriched form. | 07-04-2013 |
| 20130184470 | Process for preparing 5-[1-(4-chlorophenyl)-methylene]-1-hydroxymethyl-2,2-dimethyl-cyclopentan- ol - Process for preparing 5-[1-(4-chlorophenyl)-methylene]-1-hydroxymethyl-2,2-dimethyl-cyclopentanol | 07-18-2013 |
| 20140121382 | HYDRATE FORMS OF 1,2,4-TRIAZOLE, PROCESSES FOR MANUFACTURE THEREOF, AND COMPOSITIONS THEREOF - The present invention provides new hydrate forms of triazole, triazole alkaline salt, and alkali doped 1,2,4-triazole. The present invention also discloses processes for manufacturing new hydrate forms of triazole, triazole alkaline salt, and alkali-doped 1,2,4-triazole. The present invention also relates to compositions for different applications of new hydrate forms of triazole, triazole alkaline salt, and alkali doped 1,2,4-triazole. In addition, the present invention provides co-crystal form of triazole with acid, and methods of preparing thereof. | 05-01-2014 |
| 20160122328 | METHOD FOR PRODUCING AZOLE DERIVATIVE - In the present invention, a compound (I) is reacted with a base selected from the group consisting of a metal alkoxide, a metal hydride compound, an alkali metal, an organometallic compound of an alkali metal, an alkali metal amide, an alkali metal carbonate salt, an alkali earth metal carbonate salt, and a mixture of these to produce a compound (II). Thereafter, this reaction solution is mixed with a compound (III) and a sulfonium compound or a sulfoxonium compound in the presence of a base to obtain an azole derivative (V). | 05-05-2016 |
| 548262400 | Polycyclo ring system having the triazole ring as one of the cyclos | 3 |
| 20130116445 | TRIAZOLIUM CARBENE CATALYSTS AND PROCESSES FOR ASYMMETRIC CARBON-CARBON BOND FORMATION - Provided herein are chiral triazolium catalysts useful for asymmetric C—C bond formation and processes for their preparation. Also provided are synthetic reactions in which these catalysts are used, in particular, in asymmetric C—C bond formation. | 05-09-2013 |
| 20160039827 | ACTIVATION OF CARBONYL BETA-CARBONS FOR CHEMICAL TRANSFORMATIONS - The present invention relates to a method for synthesizing a compound of Formula (I) as defined herein, comprising: (i) activating a compound of Formula (II) as defined herein, by reacting said compound of Formula (II) with a compound of Formula (III) as defined herein, in the presence of a base, to obtain a compound of Formula (IV) as defined herein; and (ii) reacting the compound of Formula (IV) with an electrophile to obtain the compound of Formula (I). The present invention further relates to the organocatalysts used in the described methods and their respective uses. | 02-11-2016 |
| 20160190480 | 4H-Imidazo[1,2-a]imidazoles for Electronic Applications - The present invention relates to compounds of formula | 06-30-2016 |
| 548263200 | Chalcogen bonded directly to ring carbon of the triazole ring | 20 |
| 20110201822 | METHODS FOR PRODUCTION OF 1,2,4-TRIAZOL-3-ONE - Novel methods for producing 1,2,4-triazol-3-one from semicarbazide hydrochloride and formic acid are provided. In methods of this invention, water is used in removal of unreacted formic acid to increase yield and purity of produced 1,2,4-triazol-3-one. | 08-18-2011 |
| 20110263867 | METHODS FOR PRODUCTION OF 1,2,4-TRIAZOL-3-ONE - Novel methods for producing 1,2,4-triazol-3-one from semicarbazide hydrochloride and formic acid are provided. In methods of this invention, ethanol is used in removal of unreacted formic acid to increase yield and purity of produced 1,2,4-triazol-3-one. | 10-27-2011 |
| 20120232285 | Sulfonyl-1,2,4-triazole salts - The invention relates to triazole salts, to their preparation and to applications thereof. The salts have at least one anionic triazolium group which carries at least one chlorosulphonyl, fluorosulphonyl or alkoxyfluorosulphonyl group, each of the anionic groups being combined with a proton or a cation that has a valency of less than or equal to 4. The salts are useful as synthesis reagents, as chemical-reaction or polymerization catalysts, and as ion-conducting materials for electrochemical generators, supercapacitors and electrochromic devices. | 09-13-2012 |
| 20120289706 | Method for Producing Triazolinthione Derivatives and Intermediates Thereof - The present invention relates to a new process for the preparation of substituted thiotriazolo groups of the general formula (I) | 11-15-2012 |
| 20130005985 | Process Using Grignard Reagents - The present invention relates to a process using Grignard reagents for providing thio-triazolo group-containing compounds. | 01-03-2013 |
| 20130072689 | Regioselective chlorination of the phenyl ring of 4,5-dihydro-1-phenyl-1H-1,2,4-triazol-5-ones - An improved process for selectively chlorinating 4,5-dihydro-1-phenyl-1H-1,2,4-triazole-5-ones, including 4,5-dihydro-3-alkyl-1-phenyl-1H-1,2,4-triazole-5-ones and 4-haloalkyl-4,5-dihydro-3-alkyl-1-phenyl-1H-1,2,4-triazole-5-ones in the 4-position of the phenyl ring by dissolving the compounds in a synergistic ratio of polar aprotic solvents, preferably acetonitrile and N,N-dimethylformamide in a 7:3 ratio and reacting the solution with chlorine gas. | 03-21-2013 |
| 20130345435 | Preparation method of carfentrazone-ethyl - A preparation method of carfentrazone-ethyl comprises steps of: reacting 1-(5-amino-4-chloro-2-fluorophenyl)-4-difluoromethyl-3-methyl-1H-1,2,4-triazol-5-one with acrylic acid through a diazo arylation reaction to give 2-chloro-3-{2-chloro-5-[4-(difluoromethyl)-4,5-dihydro-3-methyl-5-oxo-1H-1,2,3-triazol-1-yl]-4-fluorophenyl}propionic acid; and reacting the 2-chloro-3-{2-chloro-5-[4-(difluoromethyl)-4,5-dihydro-3-methyl-5-oxo-1H-1,2,3-triazol-1-yl]-4-fluorophenyl}propionic acid with ethanol through an esterification reaction in a presence of an acidic catalyst to give carfentrazone-ethyl. | 12-26-2013 |
| 20160024028 | PHASE-TRANSFER CATALYSED FORMATION OF N-(SUBSTITUTED PHENYL) SULFONAMIDES IN WATER - A new process for making agrochemically important N-[2,4-dichloro-5-[4-(difluoro methyl)-4,5-dihydro-3-methyl-5-oxo-1H-1,2,4-triazol-1-yl] phenyl]methanesulfonamide by reacting 1-(5-amino-2,4-dichlorophenyl)-4,5-dihydro-4-difluoromethyl-3-methyl-1,2,4-triazol-5(1H)-one and methanesulfonyl chloride in water using an inorganic base to dynamically control the reaction pH and in the presence of a phase transfer catalyst suspended in an 1:1 aromatic solution. | 01-28-2016 |
| 20190144431 | METHOD FOR PRODUCING 5-HYDROXYALKYL-SUBSTITUTED 1-PHENYL-1,2,4- TRIAZOLE DERIVATIVES | 05-16-2019 |
| 548263400 | Plural chalcogen bonded directly to ring carbons of the triazole ring | 2 |
| 20100056798 | Substituted thien-3-yl-sulphonylamino(thio)carbonyl-triazolin(ethi)ones - The invention relates to processes for the preparation of compounds of general formula (I) and salts thereof: | 03-04-2010 |
| 548263600 | The 1- and 2- positions of the triazole ring are unsubstituted, or are alkyl or cycloalkyl substituted only | 1 |
| 20110009640 | BIFUNCTIONAL PHENYL ISO (THIO) CYANATES, PROCESSES AND INTERMEDIATES FOR THEIR PREPARATION - A process for preparing phenyl iso(thio)cyanates of the formula I in which a compound of the formula II or its HCl adduct is reacted with a phosgenating agent | 01-13-2011 |
| 548263800 | Halogen or nitrogen attached directly to the triazole ring by nonionic bonding | 6 |
| 20090076282 | 3-TRIAZOLYLPHENYL SULFIDE DERIVATIVE AND INSECTICIDE/ACARICIDE/NEMATICIDE CONTAINING THE SAME AS ACTIVE INGREDIENT - To provide novel 3-triazolylphenyl sulfide derivatives having excellent soil treatment activity as insecticides, miticides or nematicides for agricultural and horticultural plants. | 03-19-2009 |
| 20100069645 | 2-(5-BROMO-4-(4-CYCLOPROPYLNAPHTHALEN-1-YL)-4H-1,2,4-TRIAZOL-3-YLTHIO)ACET- IC ACID AND METHYL ESTER - A series of S-triazolyl α-mercaptoacetanilides having general structure (I) are provided, where Q is CO | 03-18-2010 |
| 20100081827 | 2-(5-BROMO-4-(4-CYCLOPROPYLNAPHTHALEN-1-YL)-4H-1,2,4-TRIAZOL-3-YLTHIO)ACET- IC ACID AND METHYL ESTER | 04-01-2010 |
| 20140163239 | METHOD FOR PREPARING AMINO-TRIAZOLINONE - The present invention relates to a method for preparing an amino-triazolinone which can be used as a raw material for amicarbazone and has chemical formula (I). The method for preparing the amino-triazolinone includes the steps of: reacting an acyl hydrazide of chemical formula (II) with a carbamating agent of chemical formula (III) or (IV) so as to obtain a hydrazine carboxylic acid of chemical formula (V); and reacting the thus-obtained hydrazine carboxylic acid of chemical formula (V) with a hydrazine hydrate under the presence of a base catalyst. According to the present invention, the amino-triazolinone may be stably prepared without using safety equipment or safety facilities for a possible leakage of phosgene, which has been used as a conventional reactant. Thus, manufacturing costs for amicarbazone, which is used as a herbicide for farm products such as sugar cane, corn, or the like, can be reduced so as to achieve improved price competitiveness, and further to achieve improved cost competitiveness compared to other herbicides. | 06-12-2014 |
| 20150336906 | METHOD FOR PREPARING AMICARBAZONE - The present invention relates to a method for preparing amicarbazone by using amino-triazolinone, which is an intermediate compound, and relates to a method for preparing amicarbazone, comprising the steps of: obtaining hydrazine carboxylic acid represented by 5 chemical formula (V) by reacting acylhydrazide represented by chemical formula (II) and a carbamating agent represented by chemical formula (III) or (IV); reacting the obtained hydrazine carboxylic acid represented by chemical formula (V) and hydrazine hydrate in the presence of a base catalyst; and reacting the obtained compound represented by chemical formula (I) 10 and an alkyl isocyanate represented by chemical formula (IV) in the presence of a base catalyst. Amino-triazolinone and amicarbazone would be stably produced by the present invention without safety gear and safety facilities for the leakage of phosgene, which has been conventionally used as a reactant. | 11-26-2015 |
| 20160046588 | METHOD FOR OBTAINING SOLUTIONS OF OTA IN A CONCENTRATED SULFURIC ACID MEDIUM; SAID SOLUTIONS; AND METHOD FOR PREPARING ONTA - A method for obtaining solutions that contain 1,2,4-triazole-5-one (OTA) in concentrated sulphuric acid, includes using 3-amino-1,2,4-triazole (ATA) as a precursor of OTA. There is also provided a method for preparing 3-nitro-1,2,4-triazole-5-one (4) (ONTA) from the solutions. | 02-18-2016 |
| 548264200 | Carbon bonded directly to the chalcogen | 3 |
| 20090012304 | Process for preparing triazolones - The present process provides a improved method for the preparation of alkylsulfanyl substituted triazoles 2 which are useful intermediates in a new process for the preparation of triazolones 20. | 01-08-2009 |
| 20100280256 | PROCESS FOR PREPARING TRIAZOLONES - The present process provides a improved method for the preparation of alkylsulfanyl substituted triazoles 2 which are useful intermediates in a new process for the preparation of triazolones 20. | 11-04-2010 |
| 548264400 | Nitrogen or additional chalcogen attached indirectly to the chalcogen by acyclic nonionic bonding | 1 |
| 20080319201 | N[S(4-ARYL-TRIAZOL-3-YL)alpha-MERCAPTOACETYL] -P-AMINO BENZOIC ACIDS AS HIV REVERSE TRANSCRIPTASE INHIBITORS - A series of S-triazolyl α-mercaptoacetanilides having N-(α-mercaptoacetyl) p amino benzoic acid derivatives. | 12-25-2008 |
| 548264800 | Nitrogen attached directly to the triazole ring by nonionic bonding | 3 |
| 20110190507 | THIOPHENE-CARBOXAMIDES USEFUL AS INHIBITORS OF PROTEIN KINASES - The present invention relates to compounds useful as inhibitors of protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising said compounds and methods of using the compounds and compositions in the treatment of various disease, conditions, or disorders. The invention also relates to processes for preparing compounds of the inventions. | 08-04-2011 |
| 20160024029 | 3,3'-DINITRO-5,5'-BISTRIAZOLE-1'-DIOL - The invention relates to 3,3′-dinitro-5,5′-bis-triazole-1,1′-diol and to salts thereof, and to an energetic active mass comprising said salts. | 01-28-2016 |
| 548265600 | The nitrogen is further bonded to hydrogen only | 1 |
| 20130023666 | ARYL (1H-1,2,4-TRIAZOL-1-YL) COMPOUND, AND PROCESS FOR PRODUCTION THEREOF - A process for production of a (1H-1,2,4-triazol-1-yl)benzene compound represented the general formula (5) | 01-24-2013 |
| 548265800 | Benzene ring bonded directly to ring nitrogen of the triazole ring, and directly to the acyclic carbon of a benzoyl or benzyl group | 8 |
| 20110034702 | METHOD FOR PREPARING 4-[3,5-BIS(2-HYDROXYPHENYL)-[1,2,4]TRIAZOL-1-YL]-BENZOIC ACID - A method for preparing 4-[3,5-bis(2-hydroxyphenyl)-[1,2,4]triazol-1-yl]benzoic acid of formula (I) by reaction of 2-(2-hydroxyphenyl)benz[e][1,3]oxazin-4-one of formula (II) with 4-hydrazinobenzoic acid of formula (III) in an organic acid or in a mixture of an organic acid and an organic solvent. | 02-10-2011 |
| 20120029202 | Process for the Preparation of 5-Substituted 3-Aryl-3-(trifluoromethyl)-3,4-dihydro-2H-pyrroles - The present invention relates to a process for the manufacturing of 5-substituted 3-aryl-3-(trifluoromethyl)-3,4-dihydro-2H-pyrroles of formula (I) | 02-02-2012 |
| 20120203007 | POLYMORPHIC FORMS OF DEFERASIROX (ICL670A) - The invention relates to crystalline forms of 4-[3,5-bis(2-hydroxyphenyl)-[1,2,4]triazol-1-yl]benzoic acid and to its amorphous form, to processes for the preparation thereof, to compositions containing the same and their uses for the manufacture of a medicament for the treatment of the human body. | 08-09-2012 |
| 20140275556 | PREPARATION OF 1,3-(SUBSTITUTED-DIARYL)-1,2,4-TRIAZOLES AND INTERMEDIATES THEREFROM - The invention in this document is related to the field of preparation of 1,3-(substituted-diaryl)-1,2,4-triazoles and certain intermediates derived therefrom, where said intermediates are useful in the preparation of certain pesticides disclosed in U.S. Pat. No. | 09-18-2014 |
| 20140275557 | PROCESS FOR THE PREPARATION OF CERTAIN TRIARYL PESTICIDE INTERMEDIATES - Certain intermediates useful in the preparation of triaryl pesticides are prepared from a substituted phenyl hydrazine and a substituted benzaldehyde by a cyclization process. | 09-18-2014 |
| 20140275558 | PREPARATION OF HALOALKOXYARYLHYDRAZINES AND INTERMEDIATES THEREFROM - This document is related to the field of preparation of haloalkoxyarylhydrazines and certain intermediates derived therefrom, where said intermediates are useful in the preparation of certain pesticides disclosed in U.S. Pat. No. 8,178,658. | 09-18-2014 |
| 20140275559 | PREPARATION OF CERTAIN (SUBSTITUTED-PHENYL)-TRIAZOLYL-(SUBSTITUTED PHENYL) MOLECULES, AND INTERMEDIATES AND INSECTICIDES RELATED THERETO - This document is related to the preparation of certain (substituted-phenyl)-triazolyl-(substituted phenyl) molecules, and intermediates related thereto, where said intermediates are useful in preparing certain insecticides. | 09-18-2014 |
| 20140275560 | PREPARATION OF 1,3-(SUBSTITUTED-DIARYL)-1,2,4-TRIAZOLES AND INTERMEDIATES THEREFROM - The invention in this document is related to the field of preparation of 1,3-(substituted-diaryl)-1,2,4-triazoles and certain intermediates derived therefrom, where said intermediates are useful in the preparation of certain pesticides disclosed in U.S. Pat. No. 8,178,658. | 09-18-2014 |
| 548266200 | Additional unsaturated hetero ring attached directly or indirectly to the triazole ring by nonionic bonding | 5 |
| 20110015404 | Electroluminescent Materials - Compounds of the general structure: Z-A-(S—B) | 01-20-2011 |
| 20130317233 | Electroluminescent Materials - Compounds of the general structure: Z-A-(S—B) | 11-28-2013 |
| 20150299144 | AZOLE DERIVATIVE, METHOD FOR PRODUCING SAME, INTERMEDIATE COMPOUND, AND AGRICULTURAL OR HORTICULTURAL CHEMICAL AGENT AND INDUSTRIAL MATERIAL PROTECTING AGENT - Provided is an azole derivative superior in disease-controlling activity contained as an active ingredient in agricultural or horticultural chemical agents. | 10-22-2015 |
| 548266400 | The additional unsaturated hetero ring is one of the cyclos of a polycyclo ring system (except alkylenedioxyphenyl) | 1 |
| 20140343293 | 1, 2, 4-TRIAZOLE-BASED DERIVATIVE, PRODUCTION PROCESS AND USE THEREOF, AND ORGANIC ELECTROLUMINESCENT DEVICE - The invention provides a 1,2,4-triazole-based derivative, a production process and use thereof, and an organic electroluminescent device. The invention belongs to the technical field of organic electroluminescence, and can give a blue light-emitting material having a higher luminescence efficiency. The 1,2,4-triazole-based derivative has a molecular structure of the following general formula, wherein A group represents an aromatic heterocyclic group having a carbon atom number of 8-18, a fused-ring aromatic group having a carbon atom number of 9-15, a fluorenyl group, or a triarylamino group. The 1,2,4-triazole-based derivative mentioned in the invention can be used in organic electroluminescent device. | 11-20-2014 |
| 548266600 | The additional unsaturated hetero ring and the triazole ring are attached to the same acyclic atom or to the same acyclic chain | 1 |
| 20110295019 | Method for Producing Hydroxymethyl Diphenyloxiranes and Corresponding 1-azolylmethyl-1,2-diphenyloxiranes - The present invention relates to a method for producing 1-hydroxymethyl-1,2-diphenyloxiranes from 2,3-diphenylpropenals by means of epoxidation and reduction. The formation of objectionable by-products can be suppressed in that the reduction is started before the 2,3-5 diphenylpropenal is completely converted. The hydroxymethyl diphenyloxiranes represent valuable intermediate products for producing 1-azolylmethyl-1,2-diphenyloxiranes, wherein the latter can be easily produced from said intermediate products by introducing the azolyl group. | 12-01-2011 |
| 548266800 | Cyano or -C(=X)-, wherein X is chalcogen, bonded directly to the triazole ring | 1 |
| 20120116095 | GLYCINE TRANSPORTER INHIBITORS - The present invention aims to provide novel compounds represented by formula [I] or pharmaceutically acceptable salts thereof: | 05-10-2012 |
| 548267200 | Nitrogen attached indirectly to the triazole ring by acyclic nonionic bonding | 6 |
| 548267400 | The nitrogen is double or triple bonded to carbon | 6 |
| 20080207915 | Process for the Preparation of 2,2'-[5-(1H-1,2,4-Triazole-1-Ylmethyl) -1,3-Phenylene] Di (2-Methylpropionitrile) - The present invention discloses a process for the preparation of Anastrozole of the formula I in high purity and in high yield. 3,5-bis(halomethyl)toluene is prepared by reacting mesitylene with N-halosuccinimide in the presence of light or dibenzoyl peroxide or azobis isobutyronitrile as a catalyst and in a chlorinated solvent. 3,5-bis(halomethyl)toluene is cyanated with metal cyanide in the presence of a catalyst and in water, organic solvent or mixture thereof at temperature of 40 to 60° C. to obtain 2,2′-(5-methyl-1,3 phenylene)diacetonitrile which is further methylated with iodomethane in the presence of base and an organic solvent at temperature of 0 to 15° C. to obtain 2,2′-(5-methyl-1,3-phenylene)di(2-methyl-propiononitrile). The product obtained is treated with N-halosuccinimide in the presence of a catalyst and in a chlorinated solvent at temperature of 60 to 100° C. to obtain 2,2′-(5-halomethyl-1,3-phenylene)di(2-methyl propionitrile) which was further treated with potassium or sodium salt 1,2,4-triazole at temperature of 20 to 50° C. in dimethyl formamide to obtain crude 2,2′-[5-( | 08-28-2008 |
| 20100099887 | Process for the Preparation of Pure Anastrozole - A process for the preparation of anastrozole which comprises: a) brominating 3,5-bis(2-cyanoprop-2-yl)toluene (II) in an organic solvent using a brominating agent to obtain 3,5-bis(2-cyanoprop-2-yl)benzylbromide (III); b) heating the reaction mass of step a) to the reflux temperature of the organic solvent for a period of time no longer than 3 hours; c) isolating and purifying the bromo intermediate (III) using an organic solvent; d) alkylating the bromo intermediate in the presence of a base, optionally a phase transfer catalyst, a 1,2,4-triazole and an organic solvent to obtain anastrozole; and e) isolating and purifying the anastrozole from an organic solvent. | 04-22-2010 |
| 20100099888 | Process for the preparation of anticancer drugs - A process for preparing Anastrozole is provided. In the process the steps of
| 04-22-2010 |
| 20110065927 | PROCESS FOR PREPARING PURE ANASTROZOLE - The present invention discloses two new related substances (6) and (7) of Anastrozole synthesis from Q.A. Salt (5) as in Scheme-1 and purification procedures to get Anastrozole (1) free from (6) and (7). | 03-17-2011 |
| 20110124877 | 5-BENZYL-4-AZOLYLMETHYL-4-SPIRO[2.4]HEPTANOL DERIVATIVES, METHODS FOR PRODUCING THE SAME, AND AGRO-HORTICULTURAL AGENTS AND INDUSTRIAL MATERIAL PROTECTING AGENTS THEREOF - To provide a novel 5-benzyl-4-azolylmethyl-4-spiro[2.4]heptanol derivative, a method for producing the same, and an agro-horticultural agent and an industrial material protecting agent containing as an active ingredient the abovementioned 5-benzyl-4-azolylmethyl-4-spiro[2.4]heptanol derivative. | 05-26-2011 |
| 20120232286 | AZOLE DERIVATIVES, METHODS FOR PRODUCING THE SAME, INTERMEDIATE THEREOF, AGRO-HORTICULTURAL AGENTS - An azole derivative according to the invention is represented by Formula (I), wherein each of R | 09-13-2012 |
| 548267800 | Chalcogen attached indirectly to the triaole ring by acyclic nonionic bonding | 4 |
| 20090312558 | PROCESS FOR THE PREPARATION OF ARYLCYCLOPROPOANE CARBOXYLIC CARBONITRILES, AND COMPOUNDS DERIVED THEREFROM - The present invention relates to an efficient process for preparing an arylcyclopropanecarbonitrile, which involves the use of sulfolane as a solvent. | 12-17-2009 |
| 20150315175 | PRODUCTION METHOD FOR CYCLOPENTANONE DERIVATIVE, INTERMEDIATE COMPOUND, AND PRODUCTION METHOD FOR INTERMEDIATE COMPOUND - A method for producing a cyclopentanone derivative represented by general formula (III) below, wherein a cyclopentanone derivative represented by general formula (III) below can be produced with higher yield since the method comprises a step in which a compound represented by general formula (II) below is obtained by reacting a compound represented by general formula (I) below with an acid. | 11-05-2015 |
| 548268200 | The triazole ring and the chalcogen are bonded directly to the same acyclic carbon | 1 |
| 20120238762 | AZOLE DERIVATIVES AND METHODS FOR PRODUCING THE SAME, INTERMEDIATE COMPOUNDS FOR THE DERIVATIVES AND METHODS FOR PRODUCING THE SAME, AND AGRO-HORTICULTURAL AGENTS AND INDUSTRIAL MATERIAL PROTECTING AGENTS CONTAINING THE DERIVATIVES - To provide an azole derivative which is contained as an active ingredient in an agro-horticultural agent having an excellent controlling effect on diseases. An azole derivative according to the invention is represented by Formula (I), wherein R | 09-20-2012 |
| 548268600 | Plural chalcogens attached indirectly to the triazole ring by acyclic nonionic bonding | 1 |
| 20140256953 | Process for Preparing Chiral 3-Triazolyl Sulphoxide Derivatives - The present invention relates to a catalytic process for preparing 3-triazolyl sulphoxide derivatives in enantiomerically pure or enantiomerically enriched form. | 09-11-2014 |
| 548268800 | The triazole ring and a hetero ring whose ring members are carbon and chalcogen are bonded directly to the same acyclic carbon | 5 |
| 20140200352 | AZOLE DERIVATIVES, METHODS FOR PRODUCING THE SAME, INTERMEDIATE THEREOF, AGRO-HORTICULTURAL AGENTS - An azole derivative according to the invention is represented by Formula (I), wherein each of R | 07-17-2014 |
| 20140213794 | AZOLE DERIVATIVES, METHODS FOR PRODUCING THE SAME, INTERMEDIATE THEREOF, AGRO-HORTICULTURAL AGENTS - An azole derivative according to the invention is represented by Formula (I), wherein each of R | 07-31-2014 |
| 20140296535 | METHOD FOR PRODUCING 4-BENZYL-1-METHYL-6-OXABICYCLO[3,2,0]HEPTANE DERIVATIVE - A 4-benzyl-1-methyl-6-oxabicyclo[3,2,0]heptane derivative is manufactured by reducing, in the presence of both a halogenating agent and a hydride-type reducing agent, a methylene moiety bound to a sulfonyloxy group in a compound represented by General Formula (II). | 10-02-2014 |
| 20140336389 | METHOD FOR MANUFACTURING 4-BENZYL-1-METHYL-6-OXABICYCLO[3,2,0]HEPTANE DERIVATIVE AND METHOD FOR MANUFACTURING AZOLE DERIVATIVE - In order to manufacture a higher yield of a 4-benzyl-1-methyl-6-oxabicyclo[3,2,0]heptane derivative, the present invention is a method for manufacturing a compound represented by General Formula (I) which includes a step for reducing a compound represented by General Formula (II) using a hydride-type reducing agent in an aprotic solvent having an amide bond. | 11-13-2014 |
| 20150018560 | Process for preparing cis-5-[1-(4-chlorophenyl)-methylene]-1-hydroxymethyl-2,2-dimethylcyclopen- tanol - The present invention relates to a process for preparing a diol of the formulae (Ia) or (Ib), or a mixture thereof, | 01-15-2015 |
| 548269200 | Processes for forming the triazole ring | 7 |
| 20090118517 | Purification process for anastrozole intermediate - The invention is directed to processes for purifying the Anastrozole intermediate, 3,5-bis(2-cyanoisopropyl)toluene, processes for producing Anastrozole, processes for preparing Anastrozole pharmaceutical compositions, and Anastrozole and Anastrozole pharmaceutical compositions prepared with the processes of the invention. | 05-07-2009 |
| 20090221837 | Process for the Preparation of Pure Anastrozole - The present invention relates to the improved process for the preparation of Anastrozole free from the impurities arising due to impure 3,5-bis-(1-cyano-1-methylethyl)benzylbromide (2) and other related impurities resulting from incomplete/over-reaction of 2,2-(5-methyl-1,3-phenylene)-bis(2-methylpropionitrile (I). | 09-03-2009 |
| 20110077410 | Process for the Preparation of 1-Phenyl-1,2,4-triazoles - The present invention relates to a process for the preparation of 1-phenyl-1,2,4-triazoles by converting phenyl hydrazides to N′-(iminomethyl)-N′-phenylacetyl hydrazides and the further reaction thereof by cyclization to give 1-phenyl-1,2,4-triazoles. | 03-31-2011 |
| 20140039199 | PROCESS FOR THE PREPARATION OF DEFERASIROX - The present invention provides improved process for the preparation of Deferasirox of formula (I). | 02-06-2014 |
| 20140275561 | PREPARATION OF HALOALKOXYARYLHYDRAZINES AND INTERMEDIATES THEREFROM - The invention in this document is related to the field of preparation of haloalkoxyarylhydrazines and certain intermediates derived therefrom, where said intermediates are useful in the preparation of certain pesticides disclosed in U.S. Pat. No. 8,178,658. | 09-18-2014 |
| 20140275562 | PREPARATION OF CERTAIN (SUBSTITUTED PHENYL)-TRIAZOLYL-(SUBSTITUTED PHENYL) MOLECULES, AND INTERMEDIATES AND INSECTICIDES RELATED THERETO - This disclosure is related to the field of preparation of certain (substituted phenyl)-triazolyl-(substituted phenyl) molecules, and intermediates related thereto, where said intermediates are useful in the preparation of certain insecticides. | 09-18-2014 |
| 20150119579 | METHOD FOR PRODUCING TRIAZOLYLMETHYL CYCLOALKANOL DERIVATIVE AND TRIAZOLYLMETHYL CYCLOALKANOL DERIVATIVE-CONTAINING COMPOSITION - Generation of by-product is reduced by producing a triazolylmethyl cycloalkanol derivative by reacting a cycloalkanone derivative and an alkali metal salt of 1,2,4-triazole in the presence of a sulfur ylide at a reaction temperature of higher than 110° C. and 140° C. or lower. | 04-30-2015 |
| 548269400 | Benzene ring bonded directly to the triazole ring | 6 |
| 20100190997 | Process for the Preparation of Letrozole - The present invention relates to the process for the preparation of Letrozole free from its regioisomer (7) and other impurities by selective extraction of desired intermediate (3) using suitable solvent and mixture of solvents. | 07-29-2010 |
| 20110015405 | Process for preparing chiral 3-triazolyl sulphoxide derivatives - The present invention relates to a catalytic process for preparing 3-triazolyl sulphoxide derivatives in enantiomerically pure or enantiomerically enriched form. | 01-20-2011 |
| 20140275563 | PREPARATION OF 1,3-(SUBSTITUTED-DIARYL)-1,2,4-TRIAZOLES AND INTERMEDIATES THEREFROM - The invention in this document is related to the field of preparation of 1,3-(substituted-diaryl)-1,2,4-triazoles and certain intermediates derived therefrom, where said intermediates are useful in the preparation of certain pesticides disclosed in U.S. Pat. No. 8,178,658. | 09-18-2014 |
| 20140275564 | PROCESS FOR THE PREPARATION OF CERTAIN TRIARYL RHAMNOSE CARBAMATES - Aryl or heteroaryl 1-substituted triazoles are prepared from 3-bromo-1H-1,2,4-triazole by reaction with a brominated or iodinated aryl or heteroaryl group. | 09-18-2014 |
| 20140275565 | PROCESS FOR THE PREPARATION OF CERTAIN TRIARYL RHAMNOSE CARBAMATES - Aryl or heteroaryl 1-substituted triazoles are prepared by cyclizing aryl or heteroaryl hydrazines with urea and alkyl orthoformates. | 09-18-2014 |
| 20160009665 | PROCESS FOR PREPARATION OF 4-(1-(4-(PERFLUOROETHOXY)PHENYL)-1H-1,2,4-TRIAZOL-3-YL)BENZOYL AZIDE | 01-14-2016 |
