| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 546276400 | The additional hetero ring is five-membered consisting of one nitrogen and four carbons | 40 |
| 20100292484 | Chiral Pyrrolidine Core Compounds en route to Inhibitors of Nitric Oxide Synthase - Diastereomeric pyrrolidine compounds and methods of preparation, as can be used en route to the preparation of a range of nitric oxide synthase inhibitors. | 11-18-2010 |
| 20110046384 | PROCESS FOR PREPARATION OF E-ISOMER OF 1-(4-METHYLPHENYL) - 1-(2-PYRID YL)-3-PYRROLIDINO PROP-1-ENE AND ACID ADDITION SALTS THEREOF - A process for preparation of E-isomer of 1-(4-methylphenyl)-1-(2-pyridyl)-3-pyrrolidinoprop-1-ene of Formula-I, and acid addition salts thereof, said process comprising; dehydrating 1-(4-methylphenyl)-1-(2-pyridyl)-3-pyrrolidinopropan-1-ol of Formula III followed by adding a base solution to obtain a mixture of E and Z isomers of 1-(4-methylphenyl)-1-(2-pyridyl)-3-pyrrolidinoprop-1-ene, and washing said mixture of E and Z isomers of 1-(4-methylphenyl)-1-(2-pyridyl)-3-pyrrolidinoprop-1-ene with water to dissolve Z isomer and to obtain E-isomer of 1-(4-methylphenyl)-1-(2-pyridyl)-3-pyrrolidinoprop-1-ene of Formula I, which is substantially free from Z isomer. | 02-24-2011 |
| 20110054180 | Magnetic Nanoparticle-Supported Glutathione as a Sustainable Organocatalyst - This invention relates to the use of nano-organocatalysts, and, more specifically, to the use of magnetic nanomaterial-supported organocatalysts. It is an object of the present invention to provide “green” catalysts and protocols. According to one embodiment of the invention, a nano-organocatalyst in the form of a magnetic nanomaterial-supported organocatalyst is provided. According to other embodiments of the invention, glutathione and cysteine are provided as organocatalysts and magnetic nanomaterial-supported glutathione and magnetic nanomaterial-supported cysteine are provided for use as nano-organocatalysts. According to another embodiment of the invention, a method of using a recyclable magnetic nanomaterial-supported organocatalyst using a totally benign aqueous protocol, without using any organic solvent in the reaction or during the workup, is provided. According to a further embodiment of the invention, a recyclable magnetic nanomaterial-supported organocatalyst for various organocatalytic reactions, including but not limited to Paal-Knorr reactions, aza-Michael addition and pyrazole synthesis, is provided. | 03-03-2011 |
| 20110251399 | METHOD FOR PRODUCING ALDEHYDES AND KETONES FROM PRIMARY AND SECONDARY ALCOHOLS - The invention relates to a method for producing aldehydes and ketones from easily accessible primary and secondary alcohols by oxidation with atmospheric oxygen or pure oxygen using a catalyst system which consists of a derivative of a free nitroxyl radical. | 10-13-2011 |
| 20120232278 | Insecticidal Aryl Pyrrolidines - The present invention provides novel aryl pyrrolidines having an excellent insecticidal action as insecticides. Aryl pyrrolidines represented by the formula (I) and use thereof as insecticide. | 09-13-2012 |
| 20130030187 | PROCESS FOR THE PREPARATION OF (R,S)-NICOTINE - A process for (R,S)-nicotine is described. Condensation of 1-(but-1-enyl) pyrrolidin-2-one with nicotinic acid ester gave 1-(but-1-enyl)-3-nicotinoylpynolidin-2-one which on treatment with an acid and a base gave myosmine. Myosmine was converted to (R,S)-nicotine by reduction followed by N-methylation. | 01-31-2013 |
| 20160176846 | CONJUGATES AND ASSOCIATED METHODS OF PRODUCING THEM FOR THE PREVENTION OR TREATMENT OF NICOTINE ADDICTION | 06-23-2016 |
| 546276700 | Polycyclo ring system having the five-membered hetero ring as one of the cyclos | 11 |
| 20130204003 | CARBAZOLE COMPOUND, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE - A novel carbazole compound is provided which can be used as a host material for a light-emitting substance (substance emitting fluorescence or substance emitting phosphorescence). A light-emitting element with high emission efficiency, and a light-emitting device, an electronic device, or a lighting device which has low power consumption are provided. A carbazole compound represented by General Formula (G1) below. | 08-08-2013 |
| 20140005404 | Heteroarylcyanine Dyes | 01-02-2014 |
| 20150318491 | CARBAZOLE COMPUND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE - A novel carbazole compound is provided which can be used as a host material for a light-emitting substance (substance emitting fluorescence or substance emitting phosphorescence). A light-emitting element with high emission efficiency, and a light-emitting device, an electronic device, or a lighting device which has low power consumption are provided. A carbazole compound represented by General Formula (G1) below. | 11-05-2015 |
| 20160060218 | STRIGOLACTAM DERIVATIVES AS PLANT GROWTH REGULATING COMPOUNDS - The present invention relates to novel strigolactam derivatives, to processes and intermediates for preparing them, to plant growth regulator compositions comprising them and to methods of using them for controlling the growth of plants and/or promoting the germination of seeds. | 03-03-2016 |
| 546277100 | Bicyclo ring system which is isoindole (including hydrogenated) | 2 |
| 20090198067 | (1S,5S)-3-(5,6-Dichloropyridin-3-YL)-3,6-Diazabicyclo[3.2.0]Heptane Benzenesulfonate - The present invention relates to the salt (1S,5S)-3-(5,6-dichloropyridin-3-yl)-3,6-diazabicyclo[3.2.0]heptane benzenesulfonate and to methods of preparing the salt. | 08-06-2009 |
| 20110237802 | LENALIDOMIDE SOLVATES AND PROCESSES - The present application relates to lenalidomide salts and solvates, and processes for the preparation thereof. | 09-29-2011 |
| 546277400 | Bicyclo ring system which is indole (including hydrogenated) | 5 |
| 20110054181 | NEAR INFRARED FLUORESCENT IMAGING AGENT - A compound represented by general formula (I) below, or a pharmacologically acceptable salt thereof: | 03-03-2011 |
| 20150307548 | FPR1 ANTAGONIST DERIVATIVES AND USE THEREOF - A dipeptide derivative as formyl peptide receptor 1 (FPR1) antagonist is provided. The dipeptide derivative is represented by formula (I), wherein: | 10-29-2015 |
| 20150315143 | N-Heterocyclic Carbene-Catalyzed Synthesis of 2-Aryl Indoles - Transition metal-free catalytic methods for access to 2-arylindole compounds. | 11-05-2015 |
| 546277700 | Chalcogen attached directly to the five-membered hetero ring by nonionic bonding | 1 |
| 20160039755 | OXINDOLE COMPOUNDS, SOLVENT-FREE SYNTHESIS AND USE THEREOF - The present invention discloses oxindole compounds and a single step, one pot reaction for the synthesis of oxindole derivates via a solvent free Passerini reaction of isocyanides, isatins and carboxylic acids. | 02-11-2016 |
| 546278100 | Having -C(=X)-, wherein X is chalcogen, bonded directly to the five- membered hetero ring | 1 |
| 20100145060 | Schwartz Reagents: Methods of In Situ Generation and Use - Embodiments of the invention provide a method of using Schwartz Reagent, Cp | 06-10-2010 |
| 546278400 | Chalcogen attached directly to the five-membered hetero ring by nonionic bonding | 14 |
| 20100228035 | Functionalized Ionic Liquids, and Methods of Use Thereof - One aspect of the present invention relates to ionic liquids comprising a pendant Bronsted-acidic group, e.g., a sulfonic acid group. Another aspect of the present invention relates to the use of an ionic liquid comprising a pendant Bronsted-acidic group to catalyze a Bronsted-acid-catalyzed chemical reaction. A third aspect of the present invention relates to ionic liquids comprising a pendant nucleophilic group, e.g., an amine. Still another aspect of the present invention relates to the use of an ionic liquid comprising a pendant nucleophilic group to catalyze a nucleophile-assisted chemical reaction. A fifth aspect of the present invention relates to the use of an ionic liquid comprising a pendant nucleophilic group to remove a gaseous impurity, e.g., carbon dioxide, from a gas, e.g., sour natural gas. | 09-09-2010 |
| 20110306769 | PROCESS FOR PRODUCING PYRROLE COMPOUND - The present invention provides a production method of a sulfonylpyrrole compound useful as a pharmaceutical product, a production method of an intermediate used for the method, and a novel intermediate. The present invention relates to a method of producing sulfonylpyrrole compound (VIII), which includes reducing compound (III) and hydrolyzing the reduced product to give compound (IV), subjecting compound (IV) to a sulfonylation reaction to give compound (VI), and subjecting compound (VI) to an amination reaction. | 12-15-2011 |
| 20120209006 | PROCESS FOR THE PREPARATION OF (R,S)-NICOTINE - A process for (R,S)-nicotine is described. Condensation of 1-(but-1-enyl)pyrrolidin-2-one with nicotinic acid ester gave 1-(but-1-enyl)-3-nicotinoylpyrrolidin-2-one which on treatment with an acid and a base gave myosmine. Myosmine was converted to (R,S)-nicotine by reduction followed by N-methylation. | 08-16-2012 |
| 20130030188 | PROCESS FOR THE PREPARATION OF (R,S)-NICOTINE - A process for (R,S)-nicotine is described. Condensation of 1-(but-1-enyl) pyrrolidin-2-one with nicotinic acid ester gave 1-(but-1-enyl)-3-nicotinoylpyrrolidin-2-one which on treatment with an acid and a base gave myosmine. Myosmine was converted to (R,S)-nicotine by reduction followed by N-methylation. | 01-31-2013 |
| 20140031554 | PROCESS FOR PREPARING RACEMIC NICOTINE - Provided is a process for preparing racemic nicotine from 1-methyl-3-nicotinoyl-2-pyrrolidone or a salt thereof using one-pot process. The process comprises the following steps: 1) in a reaction vessel, reacting 1-methyl-3-nicotinoyl-2-pyrrolidone or a salt thereof in the presence of a suitable solvent and a strong acid by heat; after the reaction is complete, cooling the same and adjusting the pH to 7-8 with alkali; and 2) directly adding a reductant into the above vessel, and after the reaction, purifying the product so as to obtain high purity racemic nicotine or a salt thereof. | 01-30-2014 |
| 20140046069 | PESTICIDAL ARYLPYRROLIDINES - Arylpyrrolidines of Formula (I): wherein each substituent is as defined in the specification, and use thereof as pesticides and animal paracite-controlling agents. | 02-13-2014 |
| 20140163234 | Process for preparing N-substituted 1H-pyrazole-5-carbonylchloride compounds - The present invention relates to a process for preparing an N-substituted 1H-pyrazole-5-carbonylchloride compound of the formula (I) | 06-12-2014 |
| 20140303378 | PROCESS FOR PRODUCING PYRROLE COMPOUND - The present invention provides a production method of a sulfonylpyrrole compound useful as a pharmaceutical product, a production method of an intermediate used for the method, and a novel intermediate. The present invention relates to a method of producing sulfonylpyrrole compound (VIII), which includes reducing compound (III) and hydrolyzing the reduced product to give compound (IV), subjecting compound (IV) to a sulfonylation reaction to give compound (VI), and subjecting compound (VI) to an amination reaction. | 10-09-2014 |
| 20150329520 | CONJUGATES AND ASSOCIATED METHODS OF PRODUCING THEM FOR THE PREVENTION OR TREATMENT OF NICOTINE ADDICTION - The present invention relates in part to chemical compounds, and methods for producing these compounds. The compounds may also be incorporated into compositions to enhance quit rates or reduce relapse in smoking cessation and further in treating nicotine-related dependence. | 11-19-2015 |
| 20160009646 | METHOD FOR PRODUCING SULFONYL CHLORIDE COMPOUND | 01-14-2016 |
| 20160096821 | Chiral Synthesis of Pyrrolidine Core Compounds en route to Neuronal Nitric Oxide Synthase Inhibitors - A chiral synthesis of pyrrolidine compounds en route to selective neuronal nitric oxide synthase inhibitors, and representative inhibitor compounds heretofore unattainable. | 04-07-2016 |
| 546278700 | Plural chalcogens attached directly to the five-membered hetero ring by nonionic bonding | 3 |
| 20110313168 | METHOD FOR PREPARING ACTIVATED ESTERS - The invention relates to a method for preparing an activated ester of the formula (I), where R is a (C | 12-22-2011 |
| 20120165537 | METHODS FOR THE PREPARATION OF CHARGED CROSSLINKERS - Processes for the preparation of charged crosslinkers bearing a sulfonic acid moiety are disclosed. These procedures also optionally include methods to convert the resulting products to substantially a single salt form. | 06-28-2012 |
| 20140135502 | METHODS FOR THE PREPARATION OF CHARGED CROSSLINKERS - Processes for the preparation of charged crosslinkers bearing a sulfonic acid moiety are disclosed. These procedures also optionally include methods to convert the resulting products to substantially a single salt form. | 05-15-2014 |
| 546279100 | Nitrogen or -C(=X)-, wherein X is chalcogen, attached directly to the five- membered ring by nonionic bonding | 6 |
| 20090118515 | PROCESS FOR PREPARING INTERMEDIATES USEFUL TO PREPARE CERTAIN ANTIBACTERIAL N-FORMYL HYDROXYLAMINES - The present invention is directed to a process for preparing intermediates that are useful to prepare certain antibacterial N-formyl hydroxylamine compounds which are peptide deformylase inhibitors. | 05-07-2009 |
| 20100145061 | N-(1-PHENYL-2-ARYLETHYL)-4,5-DIHYDRO-2H-PYRROL-5-AMINE COMPOUNDS AS SUBTYPE SELECTIVE MODULATORS OF ALPHA2B OR ALPHA2B AND ALPHA2C ADRENOCEPTORS - The present invention provides compounds which are N-(1-phenyl-2-arylethyl)-4,5-dihydro-2H-pyrrol-5-amine compounds and are subtype selective modulators of alpha 2B or alpha 2B and alpha 2C adrenoreceptors and are selected from the group of compounds represented by the formula | 06-10-2010 |
| 20110152533 | PRODRUGS OF INHIBITORS OF PLASMA KALLIKRIEN - The present invention provides prodrugs of compounds that inhibit the activity of plasma kallikrein (PK) and methods of preventing and treating plasma kallikrein dependent diseases or conditions, for example, diabetic macular edema, with the prodrugs having the formula: | 06-23-2011 |
| 20110319626 | Use of Atorvastatin Lactols as Medicaments - This invention relates to the discovery of novel atorvastatin analogues. More specifically, the invention relates to novel atorvastatin analogues which have utility in treating conditions treatable by the inhibition of HMG-CoA reductase. | 12-29-2011 |
| 20130303773 | Rosuvastatin and Atorvastatin Derivatives - This invention relates to the discovery of novel rosuvastatin and atorvastatin analogues. | 11-14-2013 |
| 20160008340 | PHARMACEUTICAL COMPOSITION INCLUDING MIGRATORY FACTOR FOR GUIDING PLURIPOTENT STEM CELLS TO INJURY | 01-14-2016 |
| 546279400 | Nicotine, per se, or its salts | 2 |
| 20120197022 | PROCESS FOR THE RESOLUTION OF (R,S)-NICOTINE - (R,S)-Nicotine was resolved through diastereomeric salt formation using dibenzoyl-d-tartaric acid and dibenzoyl-l-tartaric acid to obtain enantiomerically pure (S)-nicotine and (R)-nicotine. | 08-02-2012 |
| 20160115150 | PROCESS FOR THE PREPARATION OF (R,S)-NICOTINE - A method of preparing (R,S)-nicotine, comprising reacting a nicotinate ester with N-vinyl-2-pyrrolidinone in the presence of a base and a solvent to form a first mixture, combining the first mixture with an acid to form a second mixture comprising an aqueous layer, separating the aqueous layer from second mixture, combining the separated aqueous layer with an acid to form a third mixture, combining the third mixture with a base to form a fourth mixture comprising myosamine, reducing myosamine to nornicotine using a reducing agent, and methylating the nornicotine to yield R,S-nicotine. | 04-28-2016 |
