| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 546269700 | 1,3-thiazoles (including hydrogenated) | 28 |
| 20090118514 | PROCESSES FOR PREPARING PIOGLITAZONE AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS - An improved process for the preparation of pioglitazone and its pharmaceutically acceptable salts by reducing 5-[4-[2-(5-ethyl-2-pyridyl)ethoxy]benzilidene]-2,4-thiazolidinedione with sodium borohydride in presence of a cobalt ion and dimethyl glyoxime. More particularly the cobalt ion used is cobalt chloride hexahydrate, or, cobalt (II) nitrate hexahydrate in presence of mixture of DMF and water as solvents. | 05-07-2009 |
| 20090270630 | PROCESS FOR THE SYNTHESIS OF BENZYLIDENE ROSIGLITAZONE BASE - Process for the synthesis of 5-{4-[N-methyl-N-(2-pyridyl)-amino-ethoxy]-benzylidene}-thiazolidine-2,4-dione (INN name: benzylidene-rosiglitazone) of formula (I), which consist of the following steps: | 10-29-2009 |
| 20110046382 | PROCESS FOR THE PREPARATION OF 4-[2-(5-ETHYL-2-PYRIDYL)ETHOXY]NITROBENZENE AND PIOGLITAZONE - A process for the preparation of 4-[2-(5-ethyl-2-pyridyl)ethoxy]nitrobenzene is described, which comprises the step of reacting 2-(5-ethyl-2-pyridyl)ethanol with 1-fluoro-4-nitrobenzene in acetone in the presence of an alkali metal hydroxide. The intermediate 4-[2-(5-ethyl-2-pyridyl)ethoxy]nitrobenzene is used for the preparation of pioglitazone. | 02-24-2011 |
| 20120277440 | IMINO DERIVATIVES, PROCESS FOR PREPARATION THEREOF, AND INSECTICIDES CONTAINING SAME - To provide a novel imino derivative capable of being an insecticide compound which is excellent in characteristics such as sustained effects and a broad spectrum. | 11-01-2012 |
| 20120309975 | PPAR-SPARING THIAZOLIDINEDIONE SALTS FOR THE TREATMENT OF METABOLIC DISEASES - The present invention relates to novel salts of thiazolidinediones and other pharmaceutical agents that are useful for treating and/or preventing metabolic diseases (e.g., diabetes, or neurodegenerative diseases (e.g., Alzheimer's Disease). | 12-06-2012 |
| 20130211092 | SYNTHESIS FOR THIAZOLIDINEDIONE COMPOUNDS - The present invention provides novel methods for synthesizing PPARγ sparing compounds, e.g., thiazolidinediones, that are useful for preventing and/or treating metabolic disorders such as diabetes, obesity, hypertension, and inflammatory diseases. | 08-15-2013 |
| 20140206879 | DIPEPTOID PRODRUGS AND THEIR USE - The present application relates to prodrug derivatives of 2-amino-6-({[2-(4-chlorophenyl)-1,3-thiazol-4-yl]methyl}thio)-4-[4-(2-hydroxyethoxy)phenyl]pyridine-3,5-dicarbonitrile, processes for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, especially of cardiovascular disorders. | 07-24-2014 |
| 20140378687 | Synthesis for Thiazolidinedione Compounds - The present invention provides novel methods for synthesizing PPARγ sparing compounds, e.g., thiazolidinediones, that are useful for preventing and/or treating metabolic disorders such as diabetes, obesity, hypertension, and inflammatory diseases. | 12-25-2014 |
| 20150051402 | Thiazole Methylamino Pyridine Compounds and Preparation Method Therefor - Disclosed are thiazole methylamino pyridine compounds represented by the general formula (I) having fungicidal, insecticidal/acaricidal, and herbicidal activity, the preparation method thereof, the fungicidal, insecticidal/acaricidal, and herbicidal compositions containing the compounds of the present invention, and the use and the method for controlling fungi, insects/acari and weeds of the compounds of the present invention. | 02-19-2015 |
| 20160038472 | AGENT FOR THE PROPHYLAXIS AND/OR TREATMENT OF NEOPLASTIC DISEASES - The invention relates to a novel agent in the form of rhodanine derivatives, which has prophylactic, antiproliferative and antimetastatic activity. Said agent can find use in medicine and pharmacology for the prophylaxis and/or treatment of neoplastic diseases of variable localisation. | 02-11-2016 |
| 20160130264 | Synthesis of Fatostatin Based Polycyclic Compounds - The present invention relates to methods and strategies for large-scale synthesis of compounds having the chemical structure: | 05-12-2016 |
| 546270100 | Polycyclo ring system having the 1,3-thiazole ring as one of the cyclos | 4 |
| 20090082571 | Intermediates of 2-substituted carbapenem derivatives and process for production thereof - The present invention relates to compounds represented by formula (1) and a process for producing the same. The use of these compounds can realize the production of carbapenem derivatives having potent antimicrobial activity and a wide antimicrobial spectrum in a safe and cost-effective manner. | 03-26-2009 |
| 20120271054 | IMIDAZOTHIAZOLE-CHALCONE DERIVATIVES AS POTENTIAL ANTICANCER AGENTS AND PROCESS FOR THE PREPARATION THEREOF - The present invention provides a compounds 7a-f to 18a-f and 19a-f to 30a-f of general formula A, useful as potential anticancer agents against human cancer cell lines. The present invention further provides a process for the preparation of imidazothiazole-chalcone hybrids 7a-f to 18a-f and 19a-f to 30a-f of general formula A. | 10-25-2012 |
| 20130150587 | Process for the Preparation of Esomeprazole Magnesium Dihydrate - A process for preparing Form A of (S)-5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)-methyl]sulfinyl]-1H-benzimidazole magnesium dihydrate, processes for preparing various intermediates useful in the preparation of Form A of (S)-5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)-methyl]sulfinyl]-1H-benzimidazole magnesium dihydrate and a novel polymorphic Form II of 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)-methyl]thio]-1H-benzimidazole. | 06-13-2013 |
| 20130324734 | 2-ANILINO NICOTINYL LINKED 2-AMINO BENZOTHIAZOLE CONJUGATES AND PROCESS FOR THE PREPARATION THEREOF - The present invention provides compounds of general formula A useful as potential anticancer agents against human cancer cell lines and apoptosis inducers. The present invention further provides a process for the preparation of 2-anilino nicotinyl linked 2-amino benzothiazole conjugates of general formula (A), wherein R | 12-05-2013 |
| 546270400 | 1,3-thiazole ring bonded directly to the six-membered hetero ring | 10 |
| 20090281324 | PROCESSES FOR THE PREPARATION OF O-[5-(4-AMINO-THIAZOL-2-YL)-PYRIDIN-2-YLMETHYL]-HYDROXYLAMINE - The present invention relates generally to novel methods for the synthesis of O-[5-(4-amino-thiazol-2-yl)-pyridin-2-ylmethyl]-hydroxylamine which is an essential reagent in the synthesis of one of the bridged erythromycin derivatives and their respective pharmaceutically acceptable salts in PCT Application WO 03/097659 A1. In particular, the present invention relates to processes and intermediates for the preparation of a compound of formula (Ia): | 11-12-2009 |
| 20100094016 | Thiazoline acid derivatives - The present invention relates to novel thiazoline acids and derivatives thereof useful as chelators of trivalent metals in therapeutic applications. For example, the thiazoline acid derivatives are useful in diagnosing and treating pathological conditions associated with an excess of trivalent metals in humans and animals. | 04-15-2010 |
| 20100222590 | Tetomilast Polymorphs - The present invention provides a tetomilast crystal that is industrially easily produced in a large volume. (1) a tetomilast hydrate crystal having a powder X-ray diffraction spectrum that is substantially the same as the powder X-ray diffraction spectrum shown in FIG. | 09-02-2010 |
| 20110054179 | MMP-2 AND/OR MMP-9 INHIBITOR - The present invention provides a highly safe pharmaceutical preparation effective for diseases caused by MMP-2 and/or MMP-9. The pharmaceutical preparation contains, as an active ingredient, at least one member selected from the group consisting of thiazole derivatives represented by Formula (1): | 03-03-2011 |
| 20110172433 | NOVEL IMINO DERIVATIVES, METHODS FOR PRODUCING THE SAME AND INSECTICIDES CONTAINING THE SAME - [Technical Problem] To provide a novel imino derivative capable of being an insecticide compound having excellent characteristics such as sustained effects and broad spectrum. | 07-14-2011 |
| 20120264942 | METHOD FOR SCREENING OSTEOPONTIN INHIBITOR AND INHIBITOR OBTAINED FROM THE METHOD - Provided is a compound found by screening a material for inhibiting an osteopontin, in which the material for inhibiting the osteopontin can increase effectiveness as an excellent material for inhibiting an osteoporosis. | 10-18-2012 |
| 20130324735 | PROCESSES TO PRODUCE CERTAIN 2-(PYRIDINE-3-YL)THIAZOLES - The invention disclosed in this document is related to the field of processes to produce certain 2-(pyridine-3-yl)thiazoles as intermediates for the synthesis of pesticidal thiazole amides. | 12-05-2013 |
| 20130324736 | PROCESSES TO PRODUCE CERTAIN 2-(PYRIDINE-3-YL)THIAZOLES - The invention disclosed in this document is related to the field of processes to produce certain 2-(pyridine-3-yl)thiazoles as intermediates for the synthesis of pesticidal thiazole amides. | 12-05-2013 |
| 20130331579 | Synthesis of 2-carboxamide cycloamino urea derivatives - Provided herein are processes and intermediate compounds useful for the preparation of 2-carboxamide cycloamino urea derivatives, and useful intermediates therefore. | 12-12-2013 |
| 20140073797 | PROCESSES FOR THE PREPARATION OF 2-FLUORO 6-11 BICYCLIC ERYTHROMYCIN DERIVATIVES - The present invention relates to processes and intermediates for the preparation of 2-fluoro 6-11 bicyclic erythromycin derivatives. In particular, the present invention relates to processes and intermediates for the preparation of a compound of formula (X-c): | 03-13-2014 |
| 546270700 | Nitrogen attached directly to the 1,3-thiazole ring by nonionic bonding | 3 |
| 20130245273 | AMINOPYRIDINES USEFUL AS INHIBITORS OF PROTEIN KINASES - The present invention relates to compounds useful as inhibitors of protein kinases. The invention also provides pharmaceutically acceptable compositions comprising those compounds and methods of using the compounds and compositions in the treatment of various disease, conditions, and disorders. The invention also provides processes for preparing compounds of the invention. | 09-19-2013 |
| 20130324737 | PROCESSES TO PRODUCE CERTAIN 2-(PYRIDINE-3-YL)THIAZOLES - The invention disclosed in this document is related to the field of processes to produce certain 2-(pyridine-3-yl)thiazoles as intermediates for the synthesis of pesticidal thiazole amides. | 12-05-2013 |
| 20190144438 | PRODUCTION METHOD OF THIAZOLE DERIVATIVE | 05-16-2019 |
