| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 546229000 | Nitrogen attached indirectly to the piperidine ring by nonionic bonding | 17 |
| 20100094015 | INDAZOLE HAVING ANALGESIC ACTIVITY - An intermediate of formula (II) | 04-15-2010 |
| 546230000 | Cyano attached indirectly to the piperidine ring by nonionic bonding | 2 |
| 20100261910 | Process for the palladium-catalyzed coupling of terminal alkynes with aryl tosylates - The present invention relates to a process for the regioselective synthesis of compounds of the formula (I), | 10-14-2010 |
| 20120130079 | Compounds That Suppress Cancer Cells and Exhibit Antitumor Activity - The present invention provides compounds S3I-201.1066 (Formula 1) and S3I-201.2096 (Formula 2) as selective Stat3 binding agents that block Stat3 association with cognate receptor pTyr motifs, Stat3 phosphorylation and nuclear translocation, Stat3 transcriptional function, and consequently induced Stat3-specific antitumor cell effects in vitro and antitumor response in vivo. | 05-24-2012 |
| 546231000 | Plural acyclic nitrogens bonded directly to the same carbon or single bonded directly to each other | 3 |
| 20110046381 | NOVEL 4-{3-[4-(3-{4-[AMINO (BUTOXYCARBONYLIMINO) METHYL] PHENOXY} PROPYL)-1-PIPERIDINYL] PROPOXY]-N'-(BUTOXYCARBONYL) BENZAMIDINE CRYSTALS - Problems To provide novel crystals of 4-{3-[4-(3-{4-[amino(butoxycarbonylimino)methyl]phenoxy}propyl)-1-piperidinyl]propoxy}-N′-(butoxycarbonyl)benzamidine. | 02-24-2011 |
| 20140073795 | Process for the preparation of substituted pyrimidine derivatives - The present invention is directed to processes for the preparation of substituted pyrimidine derivatives, useful as intermediates in the synthesis of histamine H | 03-13-2014 |
| 20150353517 | METHOD FOR THE SYNTHESIS OF A HYDRAZINE THAT CAN BE USED IN THE TREATMENT OF THE PAPILLOMA VIRUS - The invention relates to a method for producing a hydrazine of general formula (I) and the pharmaceutically acceptable salts thereof from an amine of formula (II), characterised in that said method uses a urea of formula (III) as a synthesis intermediate. | 12-10-2015 |
| 546232000 | Chalcogen attached indirectly to the piperidine ring by nonionic bonding | 11 |
| 546233000 | Acyclic nitrogen bonded directly to a -C(=X)- group, wherein X is chalcogen | 10 |
| 20100056794 | PROCESS FOR THE PREPARATION OF 2,5-BIS-(2,2,2-TRIFLUOROETHOXY)-N-(2-PIPERIDYL-METHYL)-BENZAMIDE AND SALTS THEREOF - Process for the preparation of 2,5-bis(2,2,2-trifluoroethoxy)-N-(2-piperidylmethyl)benzamide, its pharmaceutically acceptable salts and important intermediates thereof that involves 1,4-dihalotoluenes as starting material. The method involves a technique for preparing the starting material 2,5-bis(2,2,2-trifluoroethoxy)toluene in high yields by reacting 1,4-dibromotoluene with 2,2,2-trifluoroethanol in presence of a base and a copper-containing catalyst. | 03-04-2010 |
| 20100063292 | PROCESS FOR THE PREPARATION OF TRIFLUOROETHOXYTOLUENES. - The present invention relates to an process for the preparation 2,5-bis(2,2,2-trifluoroethoxy)toluene [II]. The compound 2,5-bis(2,2,2-trifluoroethoxy)toluene is useful as intermediate for pharmaceutical industry, especially useful as an intermediate for the preparation of Flecainide and pharmaceutically acceptable salts. | 03-11-2010 |
| 20120283445 | [4-(5-AMINOMETHYL-2-FLUORO-PHENYL)-PIPERIDIN-1-YL]-[7-FLUORO-1-(2-METHOXY-- ETHYL)-4-TRIFLUOROMETHOXY-1H-INDOL-3-YL]-METHANONE AS AN INHIBITOR OF MAST CELL TRYPTASE - The present invention is directed to an indole benzylamine compound of formula I: | 11-08-2012 |
| 20130225825 | PROCESS FOR THE PREPARATION OF TRYPTASE INHIBITORS - This invention is directed to processes for the preparation of a compound of the formula I or salt thereof, | 08-29-2013 |
| 20150148544 | NOVEL REAGENTS AND METHOD FOR CONJUGATING BIOLOGICAL MOLECULES - A compound of the general formula X—[NR—CO—Ar—CO—(CH═CH) | 05-28-2015 |
| 546234000 | Plural carbocyclic rings containing | 5 |
| 20080200684 | Process for Preparing Ethyl (s)-2-Ethoxy-4-[N-[1-(2-Piperidinophenyl)-3-Methyl-1-Butyl]Aminocarbonyl Methyl]Benzoate and Use Thereof for the Preparation of Repaglinide - Described herein is an improved, commercially viable and industrially advantageous process for the preparation of Repaglinide intermediate, ethyl (S)-2-ethoxy-4-[N-(1-(2-piperidino-phenyl)-3-methyl-1-butyl)-aminocarbonylmethyl]-benzoate. The process provides the Repaglinide intermediate in higher yield and purity compared to the previously disclosed processes, thereby providing for production of Repaglinide and its pharmaceutically acceptable salts in high purity and in high yield. | 08-21-2008 |
| 20080300410 | Organic Compounds - The present invention relates to salts of aryl compounds as discussed below and to methods of manufacture thereof, as well as other subject matter. More particularly, the invention relates to salts useful as intermediates for the synthesis of the cinnamanilide of formula (Y): where R | 12-04-2008 |
| 20100076198 | Crystalline forms of Fentanyl Alkaloid - The present invention provides crystalline forms of fentanyl alkaloid and methods for preparing crystalline forms of fentanyl alkaloid. | 03-25-2010 |
| 20120065404 | Process for Preparing Ethyl (s)-2-Ethoxy-4-[N-[1-(2-Piperidinophenyl)-3-Methyl-1-Butyl]Aminocarbonyl Methyl]Benzoate and Use Thereof for the Preparation of Repaglinide - Described herein is an improved, commercially viable and industrially advantageous process for the preparation of Repaglinide intermediate, ethyl (S)-2-ethoxy-4-[N-(1-(2-piperidino-phenyl)-3-methyl-1-butyl)-aminocarbonylmethyl]-benzoate. The process provides the Repaglinide intermediate in higher yield and purity compared to the previously disclosed processes, thereby providing for production of Repaglinide and its pharmaceutically acceptable salts in high purity and in high yield. | 03-15-2012 |
| 20120071660 | RESOLUTION OF (.+-.)-METHYL PHENYL[4-[4-[[[4'(TRIFLUOROMETHYL)-2- BIPHENYLYL]CARBONYL]AMINO]PHENYL]-1-PIPERIDINYL]ACETATE - The present invention relates to a resolution process of (±)-methyl phenyl[4-[4-[[[4′-(trifluoromethyl)-2-biphenylyl]carbonyl]amino]phenyl]-1-piperidinyl]acetate to isolate the MTP (microsomal triglyceride transfer protein) inhibitor methyl (2S)-phenyl[4-[4-[[[4′-(trifluoromethyl)-2-biphenylyl]carbonyl]amino]phenyl]-1-piperidinyl]acetate and an epimerisation procedure for racemizing methyl (2R)-phenyl[4-[4-[[[4′-(trifluoromethyl)-2-biphenylyl]carbonyl]amino]phenyl]-1-piperidinyl]acetate. | 03-22-2012 |
| 546235000 | The chalcogen, X, is in a -C(=X)- group | 1 |
| 20090187025 | Pharmaceutical composition for promoting angiogenesis - The present invention provides a pharmaceutical composition for promoting angiogenesis, which has an angiogenesis promoting action even in a vascular culturing system without effect of microcirculation. A pharmaceutical composition for promoting angiogenesis of the present invention comprises at least one compound selected from a group consisting of a piperidine compound represented by the general formula (1) or salts thereof: | 07-23-2009 |
