| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 546225000 | Having -C(=X)-, wherein X is chalcogen, bonded directly to the piperidine ring | 7 |
| 20090187024 | ROPIVACAINE HYDROCHLORIDE ANHYDRATE AND THE PREPARATION THEREOF - The invention pertains to a process for preparing stable anhydrous Ropivacaine hydrochloride, the process involving preparing Ropivacaine hydrochloride from Ropivacaine base, wherein Ropivacaine base is provided having a chiral purity of more than 95%, and wherein the isolation involves the use of isopropanol and hydrochloride, and is performed under water-free conditions. Ropivacaine base may be provided at high chiral purity by N-propylating L-pipecolic acid 2,6-xylidide hydrochloride in the presence of a phase transfer catalyst, wherein the reaction involves a biphasic reaction mixture containing an alkaline aqueous phase and an organic phase. The invention further pertains to stable anhydrous Ropivacaine hydrochloride obtainable by the above process. | 07-23-2009 |
| 20160052883 | POTENT NON-UREA INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE - The present invention relates to compounds that exhibit vasodilatory and anti-inflammatory effects by inhibiting the activity of soluble epoxide hydrolase (sEH). The present invention is also directed to methods of identifying such compounds, and use of such compounds for the treatment of diseases related to dysfunction of vasodilation, inflammation, and/or endothelial cells. In particular non-limiting embodiments, components of the invention may be used to treat hypertension. | 02-25-2016 |
| 546226000 | At 1-position | 4 |
| 20110184180 | Process for Preparing Aryl- and Heteroarylacetic Acid Derivatives - The present invention relates to a novel process for preparing α-arylmethylcarbonyl compound of the formula (III), characterized in that aryl- and heteroarylacetic acids and derivatives thereof of the formula (I) are reacted with α-halomethylcarbonyl compounds of the formula (II) in the presence of a palladium catalyst, of a phosphine ligand, of an inorganic base and of a phase transfer catalyst, optionally using an organic solvent. | 07-28-2011 |
| 20120277438 | PROCESS FOR PREPARING 4-[2-(2-FLUOROPHENOXYMETHYL)PHENYL]PIPERIDINE COMPOUNDS - The invention relates to processes and intermediates for preparing compounds of formula I: | 11-01-2012 |
| 20140323735 | PROCESS FOR PREPARING 4-[2-(2-FLUOROPHENOXYMETHYL)PHENYL]PIPERIDINE COMPOUNDS - The invention relates to processes and intermediates for preparing compounds of formula I: | 10-30-2014 |
| 20160090357 | PROCESSES AND INTERMEDIATES IN THE PREPARATION OF C5aR ANTAGONISTS - Intermediates and methods are provided for the preparation of selected C5aR antagonist compounds. | 03-31-2016 |
| 546227000 | The -C(=X)- is part of a -C(=X)X- group, wherein the X's are the same or diverse chalcogens | 1 |
| 20100145057 | NOVEL PRODRUGS - The present invention describes novel prodrugs of formula (I) or their salts, process of preparation and uses thereof. | 06-10-2010 |
