Class / Patent application number | Description | Number of patent applications / Date published |
546171000 | Nitrogen, other than as nitro or nitroso, attached directly to the carbocyclic ring of the quinoline ring system by nonionic bonding | 8 |
20080281105 | Novel Quinolinium Salts and Derivatives - The present invention relates generally to the synthesis of novel quinolinium salts and derivative compounds. Such salts and compounds are useful for inhibiting the growth of cancer cells. | 11-13-2008 |
20090259044 | COMPOSITIONS AND METHODS FOR MODULATING SIRTUIN ACTIVITY - The present invention is based, in part, on our discovery of compounds that inhibit an activity of a sirtuin (e.g., compounds that inhibit or preferentially inhibit an activity of SIRT2) and are therefore believed useful in the treatment or prevention of diseases associated with sirtuin activity. These diseases include, but are not limited to, neurological disorders such as Parkinson's Disease (PD). | 10-15-2009 |
20100160636 | METHOD FOR PRODUCING OPTICALLY ACTIVE AMINES - The present invention provides a method for producing chiral amines, comprising asymmetric transfer hydrogenation of imine compounds in the presence of a hydrogen donor compound and an iridium(III) complex having a chiral prolinamide compound as a ligand. The present invention is useful for production of chiral amines in an efficient manner in terms of their optical and chemical yields. | 06-24-2010 |
20100179326 | BENZAMIDE DERIVATIVE - Compounds having high angiogenesis inhibiting activity useful as agents for effective treatment and prevention of diseases involving pathologic angiogenesis, e.g. cancer and cancer metastasis, are of formula (II), | 07-15-2010 |
20110137038 | SYNTHESIS OF SELECTED STEREOISOMERS OF CERTAIN SUBSTITUTED ALCOHOLS - A process for producing one selected stereoisomer of a substituted alcohol comprises reacting a stereoisomeric epoxide with an amine, a carboxylic acid, an amide, a sulfonyl, or a cyanide. The process avoids the production of a racemic mixture of stereoisomers of the prior art. Such a stereoisomeric substituted alcohol can be used for anti-inflammatory therapy. | 06-09-2011 |
20120035371 | PROCESS FOR THE MANUFACTURE OF NON-STEROIDAL ANTI-INFLAMMATORY AGENTS AND INTERMEDIATES THEREOF - The current invention describes novel chiral synthetic routes and intermediates for the manufacture of chiral anti-inflammatory agents of general formula VIII | 02-09-2012 |
20130079524 | FUNGICIDE N-CYCLOALKYL-N-BICYCLIC-CARBOXAMIDE DERIVATIVES - The present invention relates N-cycloalkyl-N-bicyclic-carboxamide, thiocarboxamide or N-substituted carboximidamide derivatives of formula (I) wherein A represents a carbo-linked, 5-membered heterocyclyl group; T represents O, S, N-R | 03-28-2013 |
20140296529 | BIS-QUINALDINE COMPOUND AND A PROCESS FOR PREPARING THE SAME - The present disclosure relates to a bis-quinaldine compound of formula I and a process for the same. | 10-02-2014 |