| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 544398000 | Chalcogen attached indirectly to the piperazine ring by nonionic bonding | 17 |
| 20130324731 | PROCESS FOR THE PREPARATION OF A MONO-N-ALKYLPIPERAZINE - Process for the preparation of a mono-N-alkylpiperazine of the formula I | 12-05-2013 |
| 20130324732 | Process for the Preparation of a Mono-N-Alkypiperazine - Process for the preparation of a mono-N-alkylpiperazine of the formula I | 12-05-2013 |
| 20140343287 | Process for the Manufacture of 1-[2-(2,4-Dimethyl-Phenylsulfanyl)-Phenyl]-Piperazine - A process for the manufacture of 1-[2-(2,4-dimethyl-phenylsulfanyl)-phenyl]-piperazine and pharmaceutically acceptable salts is disclosed that involves reacting compounds of formula II, III, IV under Pd catalysis and in presence of phosphine ligands to give Compound I. | 11-20-2014 |
| 20160060215 | New Process For The Synthesis Of 1-(2-((2,4-Dimethylphenyl)Thio)Phenyl)Piperazine - The present invention provides new intermediate compounds or formulae (III) and (IVa), and salts thereof, and their use in a new synthetic process for the production of 1-(2-((2,4-dimethylphenyl)thio)phenyl)piperazine (vortioxetine) an experimental drug under development for the treatment of depression and anxiety. | 03-03-2016 |
| 544399000 | The chalcogen, X, is in a -C(=X)- group | 11 |
| 20090176984 | Isotopically Enriched N-Substituted Piperazine Acetic Acids And Methods For The Preparation Thereof - In some embodiments, this invention pertains to isotopically enriched N-substituted piperazine acetic acids. In some embodiments, this invention pertains to methods for the preparation of isotopically enriched N-substituted piperazine acetic acids. | 07-09-2009 |
| 20100010222 | PHARMACEUTICAL COMPOSITION FOR TREATMENT OF DISEASES ASSOCIATED WITH DECREASE IN BONE MASS COMPRISING EP4 AGONIST AS ACTIVE INGREDIENT - A pharmaceutical composition for topical administration for prevention and/or treatment of diseases associated with decrease in bone mass comprising an EP | 01-14-2010 |
| 20110301350 | PROCESS FOR PREPARING CYCLOALKYL-SUBSTITUTED PIPERAZINE COMPOUNDS - The present invention relates to a process for preparing compounds of general formula I | 12-08-2011 |
| 544400000 | Acyclic nitrogen bonded directly to the -C(=X)- group | 8 |
| 20080275238 | SUBSTITUTED HETEROCYCLIC COMPOUNDS - Disclosed are novel heterocyclic compounds having the structure | 11-06-2008 |
| 20090318697 | PROCESS FOR PREPARING A PIPERAZINE DERIVATIVE - Disclosed is a process for preparing purified ranolazine of formula (I), which is indicated for the chronic treatment of angina, comprising reacting 1-[(2,6-dimethylphenyl)aminocarbonyl]piperazine with 1-phenoxy-2,3-epoxypropane in an inert solvent followed by precipitating the ranolazine. | 12-24-2009 |
| 20100210842 | PROCESS FOR PREPARING - The present invention relates to a method of preparing compounds of general formula I | 08-19-2010 |
| 20100249412 | Process for the manufacture of dihydropteridinones - Disclosed are processes for preparing dihydropteridinones of general formula (I) | 09-30-2010 |
| 20130090475 | Process for the Preparation of Ranolazine - A process for the preparation of ranolazine comprises the step of condensing N-(2,6-dimethylphenyl)-1-piperazinyl acetamide with a compound of formula (I) to obtain ranolazine, in which X is chlorine or bromine Ranolazine is prepared by condensing ring-opening halide which replaces epoxide in this process. | 04-11-2013 |
| 20140051858 | PREPARING METHOD OF SOLID CARBAMIC ACID DERIVATIVES - The present disclosure relates to a preparation method for powder of a carbamic acid derivative, which includes reacting a liquid amine derivative with carbon dioxide at a temperature in a range of from about −30° C. to about 500° C. at a pressure in a range of from about 0.3 MPa to about 100 MPa. In addition, the present disclosure relates to a reduction method for powder of a carbamic acid derivative to a liquid amine derivative and carbon dioxide, which includes dissolving powder of the carbamic acid derivative prepared in a solvent; refluxing the carbamic acid derivative at a temperature in a range of from about 30° C. to about 100° C.; and evaporating the solvent. The preparation method for a carbamic acid derivative powder according to the present disclosure enables easy conversion into pure powder of solid carbamic acid derivative without by-products and can remarkably reduce time and energy required for solidification by reacting carbon dioxides and amines with carbon dioxides in high pressure conditions without the use of a solvent. In addition, the prepared solid compounds can be used as a liquid amine substitute or used in a carbamic acid derivative form as necessary. | 02-20-2014 |
| 20150099886 | PREPARATION METHOD FOR SOLID POWDER OF A CARBAMIC ACID DERIVATIVE - The present application relates to a preparation method for solid powder of a carbamic acid derivative, which includes reacting an amine derivative with carbon dioxide at a temperature in a range of from about −30° C. to about 500° C. and at a pressure in a range of from about 0.3 MPa to about 100 MPa. In addition, the present disclosure relates to a reduction method for solid powder of a carbamic acid derivative to an amine derivative and carbon dioxide, which includes dissolving solid powder of the carbamic acid derivative prepared in a solvent; refluxing the carbamic acid derivative at a temperature in a range of from about 30° C. to about 100° C.; and evaporating the solvent. | 04-09-2015 |
| 20160176802 | Ethyl Benzyl Quaternary Amines of Amido Amines for Improved Antifungal properties | 06-23-2016 |
| 544401000 | The chalcogen is single bonded to both acyclic carbon and hydrogen | 2 |
| 20120108816 | PROCESS FOR PREPARING 1,4-BISHYDROXYETHYLPIPERAZINE - Process for preparing 1,4-bishydroxyethylpiperazine (BHEPIP) of the formula I | 05-03-2012 |
| 20140256944 | PROCESS FOR MAKING ALKOXYLATED PIPERAZINE COMPOUNDS - The present invention relates to an improved process for making mono- and di-alkoxylated piperazine compounds especially dihydroxyethylpiperazine. The improvement comprises the addition of an acid to the piperazine compound prior to the addition of an alkylene oxide to a reactor wherein the alkoxylated piperazine compound is prepared. Said improvement reduces the concentration of undesirable glycol ether byproducts which contribute undesirable color and foaming of the alkoxylated piperazine compounds. | 09-11-2014 |
