| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 544386000 | Having -C(=X)-, wherein X is chalcogen, bonded directly to the piperazine ring | 15 |
| 20090203909 | Method and apparatus for the use of [11C] Carbon Monoxide in Labeling Synthesis by Photo-Initiated Carbonylation - Methods and reagents for photo-initiated carbonylation with carbon-isotope labeled carbon monoxide using amines and alkyl/aryl iodides are provided. The resultant carbon-isotope labeled amides are useful as radiopharmaceuticals, especially for use in Positron Emission Tomography (PET). Associated kits for PET studies are also provided. | 08-13-2009 |
| 544387000 | Plural -C(=X)- groups bonded directly to the piperazine ring | 5 |
| 20120238756 | FATTY ACID ACETYLATED SALICYLATES AND THEIR USES - The invention relates to Fatty Acid Acetylated Salicylate Derivatives; compositions comprising an effective amount of a Fatty Acid Acetylated Salicylate Derivative; and methods for treating or preventing an inflammatory disorder comprising the administration of an effective amount of a Fatty Acid Acetylated Salicylate Derivative. | 09-20-2012 |
| 544388000 | Chalcogen or acyclic nitrogen bonded directly to at least one of the -C(=X) groups | 4 |
| 20090005562 | Method for the Production of Phenylalanine Derivatives - The invention relates to an improved method for the production of 3-amidino- or 3-guanidinophenylalanine derivatives, especially triisopropylphenyl-sulfonyl-substituted 3-amidino- or 3-guanidinophenylalanine derivatives. | 01-01-2009 |
| 20090099360 | Method for Cleaning 3-Hydroxyamidinophenylalanine Derivatives by the Precepitation and Recrystallization of Salt and an Aromatic Sulfonic Acid - The present invention relates to the preparation of 3-hydroxyamidino-phenylalanine derivatives in highly pure form which can be used for example as urokinase inhibitors. The present invention further relates to the use of high-purity 3-hydroxyamidinophenylalanine derivatives for preparing 3-amidinophenylalanine derivatives. | 04-16-2009 |
| 20110087025 | METHOD FOR PRODUCING 3-AMIDINOPHENYLALANINE DERIVATIVES - The present invention describes a method for the synthesis of enantiomerically pure 3-amidinophenylalanine derivatives, which are used as pharmaceutically effective urokinase inhibitors, by starting from 3-cyanophenylalanine derivatives. The methods of manufacture comprising only one synthesis step lead to new intermediates, namely 3-hydroxyamidino- and 3-amidrazonophenylalanine derivatives. These intermediates or their acetyl derivatives can be reduced into the desired 3-amidino-phenylalanine derivatives under gentle conditions (H | 04-14-2011 |
| 20120065398 | METHOD FOR PRODUCING 3-AMIDINOPHENYLALANINE DERIVATIVES - The present invention describes a method for the synthesis of enantiomerically pure 3-amidinophenylalanine derivatives, which are used as pharmaceutically effective urokinase inhibitors, by starting from 3-cyanophenylalanine derivatives. The methods of manufacture comprising only one synthesis step lead to new intermediates, namely 3-hydroxyamidino- and 3-amidrazonophenylalanine derivatives. These intermediates or their acetyl derivatives can be reduced into the desired 3-amidino-phenylalanine derivatives under gentle conditions (H | 03-15-2012 |
| 544389000 | The -C(=X)- is part of a -C(=X)X- group, wherein the X's are the same or diverse chalcogens | 3 |
| 20090143582 | Process for making n-(diphenylmethyl)piperazines - The compound of formula (8), in racemic or single enantiomeric form, is useful in making N-(diphenylmethyl)-piperazines such as cetirizine and levocetrizine. | 06-04-2009 |
| 20100145049 | PROCESS FOR MAKING N-(DIPHENYLMETHYL)PIPERAZINES - A compound of formula (8) or a salt thereof: | 06-10-2010 |
| 20110251389 | Process For Making N-(Diphenylmethyl)piperazines - The compound of formula (8), in racemic or single enantiomeric form, is useful in making N-(diphenylmethyl)-piperazines such as cetirizine and levocetrizine. | 10-13-2011 |
| 544390000 | Halogen or acyclic nitrogen bonded directly to the -C(=X)- group | 2 |
| 20100240893 | NITROGENOUS HETEROCYCLIC COMPOUNDS AND PROCESS FOR MAKING NITROGENOUS HETEROCYCLIC COMPOUNDS AND INTERMEDIATES THEREOF - The present invention provides nitrogen-containing heterocyclic compounds and pharmaceutically acceptable salts thereof and a process for making thereof. The compounds have inhibitory activity on the phosphorylation of kinases, which inhibits the activity of such kinases. The invention also provides intermediate compounds useful in the process, as well as final products produced by the process, and salts or prodrugs thereof. The invention further provides a method of inhibiting kinases and treating disease states in a mammal by inhibiting the phosphorylation of kinases comprising administering an effective amount of a compound according to the invention to a patient in need thereof. | 09-23-2010 |
| 20100249411 | Stereoselective Alkylation of Chiral 2-Methly-4 Protected Piperazines - In an illustrative embodiment, the present invention describes the synthesis of the following compound and similar compounds, in high stereochemical purity by a novel stereoselective alkylation process: | 09-30-2010 |
| 544391000 | Carbocyclic ring containing | 4 |
| 20100036126 | STEREOSELECTIVE SYNTHESIS OF (S)-1-METHYL-3-PHENYLPIPERAZINE - This invention provides for a compound according to Formula (1), wherein R | 02-11-2010 |
| 20100105908 | Process For The Preparation Of Levocetirizine And Intermediates Thereof - The present invention describes a novel process for the preparation of levocetirizine and pharmaceutically acceptable acid addition salts thereof using diglycolic acid or derivatives thereof and new intermediates used in that process. | 04-29-2010 |
| 20130172560 | PROCESSES FOR MAKING CYCLOPROPYL AMIDE DERIVATIVES AND INTERMEDIATES ASSOCIATED THEREWITH - Presented herein are processes for making cyclopropyl amide derivatives of formula I, and/or pharmaceutically acceptable salts thereof, and intermediates associated therewith. At least one cyclopropyl amide derivative of formula I, or pharmaceutically acceptable salt thereof is useful to treat at least one histamine H3 receptor associated condition. | 07-04-2013 |
| 20160039748 | LSD1-SELECTIVE INHIBITOR HAVING LYSINE STRUCTURE - Provided is a compound represented by the following formula (I) or a pharmaceutically acceptable salt thereof: | 02-11-2016 |
