Class / Patent application number | Description | Number of patent applications / Date published |
544357000 | Plural diazine rings | 13 |
20090076273 | SOLUBLE AMIDE & ESTER PYRAZINOYLGUANIDINE SODIUM CHANNEL BLOCKERS - The present invention relates to sodium channel blockers. The present invention also includes a variety of methods of treatment using these inventive sodium channel blockers. | 03-19-2009 |
20090306382 | CATIONIC ALKOXYAMINES - The instant invention relates to cationic alkoxyamines, which are useful as polymerization initiators/regulators in a controlled stable free radical polymerization process to produce intercalated and/or exfoliated nanoparticles from natural or synthetic clays, The invention also relates to improved nanocomposites produced by this process and to the use of these nanocomposite compositions as, for example, coatings, sealants, caulks, adhesives and as plastic additives. | 12-10-2009 |
20100152447 | Novel Method for Producing 4,4-(1-Methyl-1,2-Ethanediyl)-BIS-(2,6-Piperazinedione) - A method for preparing compounds of the formula (I) by the cyclization of tetraacetic acid alkyl esters of the formula (II) in the presence of ammonia and formamide as well as to the compounds of the formula (II), which are used in this method. | 06-17-2010 |
20100210841 | CHEMICAL PROCESS 632 - A process for preparing pharmaceutically active compounds of formula (I) or a salt thereof | 08-19-2010 |
20100216992 | MIMETIC COMPOSITIONS AND THE PRODUCTION THEREOF - The present invention generally relates to compositions including six membered heterocyclic 1,4-diaza-2-one moieties covalently bonded by a hydrazine bond and processes for producing the same. The compositions of the present invention may be utilized as peptido- and/or proteomimetics, for example,' in connection with alpha-helical proteins, like Bcl-2 proteins. | 08-26-2010 |
20110124867 | Process and intermediates for the Synthesis of heterocyclic Substituted Piperazines with CXCR3 Antagonist Activity - The present invention relates to novel processes for the preparation of the compound of the Formula A45: | 05-26-2011 |
20110257398 | Compositions and Methods Including Cell Death Inducers and Procaspase Activation - Compositions and methods are disclosed in embodiments relating to induction of cell death such as in cancer cells. Compounds and related methods for synthesis and use thereof, including the use of compounds in therapy for the treatment of cancer and selective induction of apoptosis in cells are disclosed. Compounds are disclosed in connection with modification of procaspases such as procaspase-3. In embodiments, compositions are capable of activation of procaspase-3. | 10-20-2011 |
20110295006 | CYCLIC DIPEPTIDES AS FEED ADDITIVES - Feed additives containing essential amino acids which are diketopiperazines of formulas (IV) or (V) or salts thereof are provided: | 12-01-2011 |
20120010410 | (2R)-1-(3-CHLORO-2-PYRAZINYL)-2-METHYLPIPERAZINE AND SALTS THEREOF - The present invention relates to a process for the preparation of compounds which are therapeutically active in the central nervous system. | 01-12-2012 |
20130030180 | Methods of Facilitating Neural Cell Survival Using GDNF Family Ligand (GFL) Mimetics or RET Signaling Pathway Activators - Disclosed are compounds and methods for treating neurological and other disorders by administering to a subject in need thereof an effective amount of a compound having binding and/or modulation specificity for GFRα receptor molecules, which can be mimetics of glial-derived neurotrophic factor (GDNF) family ligands (GFLs), GFRα/RET signaling pathway agonists, and/or direct RET agonists (activators). | 01-31-2013 |
20130158266 | (2R)-1-(3-Chloro-2-Pyrazinyl)-2-Methylpiperazine And Salts Thereof - The present invention relates to a process for the preparation of compounds which are therapeutically active in the central nervous system. | 06-20-2013 |
20140200346 | Novel Process for the Synthesis of 7-Chloro-4-(piperazin-1-yl)-quinoline - The present invention provides a new process of synthesis of a polymorph of 7-chloro-4-(piperazin-1-yl)-quinoline of Formula I. Said quinoline compound is substantially pure of any impurities. The present invention further provides the use of the above-mentioned polymorph of 7-chloro-4-(piperazin-1-yl)-quinoline in the synthesis of piperaquine or one of its pharmaceutically acceptable salts. | 07-17-2014 |
20150011762 | FORMATION OF HIGHER MOLECULAR WEIGHT CYCLIC POLYAMINE COMPOUNDS FROM CYCLIC POLYAMINE COMPOUNDS - The present invention provides strategies for making higher weight, cyclic polyamines from lower molecular weight, cyclic polyamine starting compounds via transamination. The higher molecular weight, cyclic polyamines are structurally similar to the lower molecular weight, cyclic polyamine starting compounds. The reactants used in the present invention include a cyclic polyamine component that comprises at least two amine groups separated from one another by at least a binary carbon atom spacing, and that can be transaminated to form a higher molecular weight, cyclic polyamine compound. The higher molecular weight, cyclic polyamine has at least two cyclic rings joined to one another through a nitrogen-containing hydrocarbyl group. Each of the cyclic rings contains two amine groups separated from one another by binary carbon atom spacing. | 01-08-2015 |