| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 544330000 | At 2-position | 69 |
| 20100004450 | Process for the preparation of substituted pyrimidine derivatives - The present invention is directed to processes for the preparation of substituted pyrimidine derivatives, useful as intermediates in the synthesis of histamine H | 01-07-2010 |
| 20130053561 | Process for the preparation of substituted pyrimidine derivatives - The present invention is directed to processes for the preparation of substituted pyrimidine derivatives, useful as intermediates in the synthesis of histamine H | 02-28-2013 |
| 20130225816 | Process for the preparation of substituted pyrimidine derivatives - The present invention is directed to processes for the preparation of substituted pyrimidine derivatives, useful as intermediates in the synthesis of histamine H | 08-29-2013 |
| 20140066624 | Process for the preparation of substituted pyrimidine derivatives - The present invention is directed to processes for the preparation of substituted pyrimidine derivatives, useful as intermediates in the synthesis of histamine H | 03-06-2014 |
| 20140121374 | PROCESS FOR THE PREPARATION OF SUBSTITUTED PYRIMIDINE DERIVATIVES - The present invention is directed to processes for the preparation of substituted pyrimidine derivatives, useful as intermediates in the synthesis of histamine H | 05-01-2014 |
| 544331000 | Additional hetero ring which is unsaturated | 40 |
| 20080214813 | METHOD FOR PRODUCING 2-(2-AMINOPYRIMIDIN-4-YL)-1H-INDOLE-5-CARBOXYLIC ACID DERIVATIVES - This invention relates to a novel process for obtaining a compound of formula I: | 09-04-2008 |
| 20080293942 | Methods of Preparing 2-Imidazol-1-Yl-4-Methyl-6-Pyrrolidin-2-Yl-Pyrimidine and 4-(1-Alkylpyrrolidin-2-Yl)-2-(1H-Imidazol-1-Yl)-6-Methylpyrimidine Derivatives - The present invention is directed to a novel, high yield method for preparing 2-imidazol-1-yl-4-methyl-6-pyrrolidin-2-yl-pyrimidine, particularly to a method of preparing 4-(1-alkylpyrrolidin-2-yl)-2-(1H-imidazol-1-yl)-6-methylpyrimidine, more particularly, 2-(2-(2-(1H-imidazol-1-yl)-6-methylpyrimidin-4-yl)pyrrolidrn-1-yl)-N-(benzo[d][1,3]dioxol-5-yh-nethyl)-N-methylethanamine. These compounds and pharmaceutical compositions thereof are inhibitors of nitric oxide synthase, are selective for inducible nitric oxide synthase, and are useful in treating diseases and disorders including inflammation and pain. | 11-27-2008 |
| 20090111985 | Synthesis of imidazooxazole and imidazothiazole inhibitors of p38 map kinase - An efficient route for the synthesis is of formula (I) of imidazooxazole and imidazothiazole inhibitors of the p38 MAP kinase pathway, useful as therapeutics for disease conditions including inflammation and auto-immune responses is described. | 04-30-2009 |
| 20090111986 | NOVEL CRYSTALS OF PYRIMIDINE COMPOUND AND PROCESS FOR PRODUCING THE SAME - Crystals of 5-[2-amino-4-(2-furyl)pyrimidin-5-yl]-1-methylpyridin-2(1H)-one having a diffraction peak at a diffraction angle (2θ±0.2°) of 9.7° and/or 21.9° in a powder X-ray diffraction are suitable for an active ingredient of a preventing and therapeutic agent for diseases such as constipation. Crystals of 5-[2-amino-4-(2-furyl)pyrimidin-5-yl]-1-methylpyridin-2(1H)-one hydrate and amorphous 5-[2-amino-4-(2-furyl)pyrimidin-5-yl]-1-methylpyridin-2(1H)-one hydrate are also suitable for an active ingredient of a preventing and therapeutic agent for diseases such as constipation. | 04-30-2009 |
| 20090264654 | PROCESS FOR THE PREPARATION OF PYRIMIDINE COMPOUNDS - A process for the preparation of a compound of Formula (1) and intermediates useful therein are provided. The process comprises reacting a compound of formula R | 10-22-2009 |
| 20100029942 | Process for the preparation of benzoimidazol-2-yl pyrimidine derivatives - The present invention is directed to benzoimidazol-2-yl pyrimidine derivatives useful as histamine H | 02-04-2010 |
| 20100076189 | PROCESS FOR THE PREPARATION OF IMATINIB AND INTERMEDIATES THEREOF - It is the object of the present invention a process for the preparation of 4-methyl-N3-[4-(3-pyridinyl)-2-pyrimidinyl]-1,3-benzenediamine and analogues thereof, intermediates useful for the synthesis of Imatinib, or 4-[(4-methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide. | 03-25-2010 |
| 20100179321 | SALT OF 5-[2-AMINO-4-(2-FURYL)PYRIMIDIN-5-YL]-1-METHYLPYRIDIN-2(1H)-ONE AND CRYSTAL THEREOF - The present invention provides a salt of 5-[2-amino-4-(2-furyl)pyrimidin-5-yl]-1-methylpyridin-2(1H)-one and a crystal thereof. | 07-15-2010 |
| 20100184981 | 2,3-DIHYDRO-IMINOISOINDOLE DERIVATIVES - A compound represented by the following general formula (1), or a salt thereof, has serine protease inhibiting activity, and particularly excellent inhibiting activity against clotting factor VIIa. This compound or a salt thereof is useful as therapeutic and/or prophylactic agents for diseases associated with thrombus formation. | 07-22-2010 |
| 20100274015 | SYNTHESIS OF 4/5-PYRIMIDINYLIMIDAZOLES VIA SEQUENTIAL FUNCTIONALIZATION OF 2,4-DICHLOROPYRIMIDINE - This invention relates to methods of making pyrimidinyl-substituted imidazole compounds by sequential substitution of the 4- and 2-chloro groups of 2,4-dichloropyrimidine, nucleophilic substitution to form pyrimidinylalkyne derivatives, oxidation to the corresponding 1,2-diketones, and cyclocondensation reactions. | 10-28-2010 |
| 20100274016 | SYNTHESIS OF 4/5-PYRIMIDINYLIMIDAZOLES VIA SEQUENTIAL FUNCTIONALIZATION OF 2,4-DICHLOROPYRIMIDINE - This invention relates to methods of making pyrimidinyl-substituted imidazole compounds by sequential substitution of the 4- and 2-chloro groups of 2,4-dichloropyrimidine, nucleophilic substitution to form pyrimidinylalkyne derivatives, oxidation to the corresponding 1,2-diketones, and cyclocondensation reactions. | 10-28-2010 |
| 20110021774 | METHOD FOR PRODUCING PYRIMIDINE COMPOUND - To provide a method for producing pyrimidine compound useful as an intermediate for agricultural chemicals or pharmaceuticals, which is simple in operation, presents high yield and produces only a small amount of by-products. | 01-27-2011 |
| 20110040090 | PROCESS FOR THE PREPARATION OF 5-(2-AMINO-PYRIMIDIN-4-YL)-2-ARYL-1H-PYRROLE-3-CARBOXAMIDES - The present invention relates to a process for the preparation of 5-(2-amino-pyrimidin-4-yl)-2-aryl-1H-pyrrole-3-carboxamides and to the useful intermediate compounds of such process. 5-(2-Amino-pyrimidin-4-yl)-2-aryl-1H-pyrrole-3-carboxamides are described and claimed in W02007110344, which also discloses processes for their preparation. These compounds can be advantageously prepared through a process which allows to obtain the desired products in high yields and purity and with a limited number of steps. The synthesis is starting from a cyano pyrrole derivative, and is characterized from the final hydrolysis of 5-(2-amino-pyrimidin-4-yl)-2-aryl-1H-pyrrole-3-carbonitrile. The compounds prepared according to the process of the present invention are endowed with protein kinase inhibiting activity and, more particularly, Cdc7 or Cdc7/Cdks inhibiting activity. The compounds are therefore useful in the treatment of a variety of cancers, cell proliferative disorders and diseases associated with protein kinases. | 02-17-2011 |
| 20110071291 | HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME - A hydrazide compound represented by the formula (1): | 03-24-2011 |
| 20110224436 | REGIOSELECTIVE REDUCTION OF FUSED PYRROLOCARBAZOLES-5,7-DIONES - The present invention relates to a method for regioselectively reducing the maleimide compounds of formula (I). The invention also relates to C | 09-15-2011 |
| 20110313160 | PREPARATION OF 5-ETHYL-2--PYRIMIDINE - Processes and intermediates for the synthesis of 5-ethyl-2-{4-[4-(4-tetrazol-1-yl-phenoxymethyl)-thiazol-2-yl]-piperidin-1-yl}-pyrimidine are provided. | 12-22-2011 |
| 20120116081 | Process for the Synthesis of 5-(Methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)-benzeneamine - The present invention provides a new method of making compounds of formula (I): | 05-10-2012 |
| 20120178932 | Process for the preparation of benzoimidazol-2-yl pyrimidine derivatgives - The present invention is directed to benzoimidazol-2-yl pyrimidine derivatives useful as histamine H | 07-12-2012 |
| 20120184740 | Process for the preparation of benzoimidazol-2-yl pyrimidine derivatives - The present invention is directed to benzoimidazol-2-yl pyrimidine derivatives useful as histamine H | 07-19-2012 |
| 20120220771 | PROCESS FOR THE PREPARATION OF 5-(2-AMINO-PYRIMIDIN-4-YL)-2-ARYL-1H-PYRROLE-3-CARBOXAMIDES - The invention relates to a process for the preparation of 5-(2-amino-pyrimidin-4-yl)-2-aryl-1H-pyrrole-3-carboxamides and to the useful intermediate compounds of such process. The process allows to obtain the desired products in high yields and purity. The synthesis is starting from the coupling of an acetal with a beta-ketoester; the resultant compound is acetylated and then reacted with a dialkyl acetal of N,N-dimethylformamide to give an intermediate which is cyclized to 5-(2-amino-pyrimidin-4-yl)-2-aryl-1H-pyrrole-3-carboxylic ester; the carboxylic ester is then hydrolyzed and the resultant carboxylic acid is finally condensed with an appropriate form of ammonia to give the desired carboxamide. The compounds prepared according to the process of the invention are endowed with protein kinase inhibiting activity and, more particularly, Cdc7 or Cdc7/Cdks inhibiting activity. The compounds are useful in the treatment of a variety of cancers, cell proliferative disorders and diseases associated with protein kinases. | 08-30-2012 |
| 20120271051 | METHOD FOR PRODUCING 2-(2-AMINOPYRIMIDIN-4-YL)-1H-INDOLE-5-CARBOXYLIC ACID DERIVATIVES - This disclosure relates to a novel process for obtaining a compound of formula I: | 10-25-2012 |
| 20120283441 | Method For Producing Pyrimidinylpyrazole Compounds - The present invention provides a method for producing a pyrimidinylpyrazole compound (1), wherein aminoguanidine (2) or its salt is reacted with a β-diketone compound (3) to produce the pyrimidinylpyrazole compound: | 11-08-2012 |
| 20130053562 | Deuterated Benzene Sulfonamide Thiazole Compounds - Deuterated forms of N-{3-[5-(2-Amino-4-pyrimidinyl)-2-(1,1-dimethylethyl)-1,3-thiazol-4-yl]-2-fluorophenyl}-2,6-difluorobenzenesulfonamide and pharmaceutical compositions containing the same. | 02-28-2013 |
| 20130053563 | PRODRUG OF TRIAZOLONE COMPOUND - By oral administration of a compound represented by the following Formula (I): the blood level of Compound (IV): which has an excellent inhibitory action against blood coagulation factor VIIa and the anticoagulant action, reaches a level sufficient for expression of its pharmacological actions. Therefore, the compound of the present invention is useful as a therapeutic and/or prophylactic agent for diseases caused by thrombus formation. | 02-28-2013 |
| 20130096304 | NILOTINIB HCL CRYSTALLINE FORMS - Crystalline forms of Nilotinib HCl are described. | 04-18-2013 |
| 20130123499 | Method for Purifying a Fused Pyrrolocarbazole Derivative - The present invention relates a method for purifying a fused pyrrolocarbazole compound known as 11-isobutyl-2-methyl-8-(2-pyrimidinylamino)-2,5,6,11,12,13-hexahydro-4Hindazolo[5,4-a]pyrrolo[3,4-c]carbazol-4-one using an acid complex thereof. The present invention also relates to a crystalline form of the acid complex. | 05-16-2013 |
| 20130123500 | ETHINYL-PYRAZOLE DERIVATIVE - Provided is a novel compound represented by formula [I] or a pharmaceutically acceptable salt thereof having antagonistic activity against group II metabolism-type glutamic acid (m-Glu) receptors. The compound or pharmaceutically acceptable salt thereof is useful as a prophylactic or therapeutic agent for diseases such as new mood disorders (depressive and bipolar disorders), anxiety disorders (generalized anxiety disorder, panic disorder, obsessive-compulsive disorder, social anxiety disorder, post-traumatic stress disorder, specific phobias, and acute stress disorder), schizophrenia, Alzheimer's disease, cognitive dysfunction, dementia, drug dependence, convulsions, tremors, pain, sleep disorders, and the like. | 05-16-2013 |
| 20130331571 | GLYCINE TRANSPORTER-INHIBITING SUBSTANCES - The present invention relates to novel compounds of formula [I] or pharmaceutically acceptable salts thereof: | 12-12-2013 |
| 20140005392 | METHOD FOR PRODUCING 2-(2-AMINOPYRIMIDIN-4-YL)-1H-INDOLE-5-CARBOXYLIC ACID DERIVATIVES | 01-02-2014 |
| 20140018537 | GPR119 AGONIST - A cyclic amine derivative represented by the formula (II) is a GPR119 agonist, and is used as an agent for treating diabetes. | 01-16-2014 |
| 20140024830 | HETEROCYCLIC RECEPTOR AGONISTS FOR THE TREATMENT OF DIABETES AND METABOLIC DISORDERS - Compounds and methods are provided for the treatment of, inter alia, Type II diabetes and other diseases associated with poor glycemic control. The compounds of the invention are orally active. | 01-23-2014 |
| 20140256942 | Benzoimidazol-2-yl pyrimidine modulators of the histamine h4 receptor - Benzoimidazol-2-yl pyrimidines, purification methods for the same, and pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by H | 09-11-2014 |
| 20140357865 | Process for the Preparation of Benzoimidazol-2-yl Pyrimidine Derivatives - The present invention is directed to benzoimidazol-2-yl pyrimidine derivatives useful as histamine H | 12-04-2014 |
| 20140364607 | BENZOIMIDAZOL-2-YL PYRIMIDINE MODULATORS OF THE HISTAMINE H4 RECEPTOR - Benzoimidazol-2-yl pyrimidines, purification methods for the same, and pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by H | 12-11-2014 |
| 20150025239 | NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME - The present invention relates to a novel organic electroluminescent compound and an organic electroluminescent device comprising the same. The organic electroluminescent compound according to the present invention is better in luminous efficiency and lifespan characteristics compared to conventional materials. Using the compounds of the present invention, it is possible to manufacture an OLED device with a long operational lifespan. In addition, the compounds can improve the power efficiency of the device to reduce overall power consumption. | 01-22-2015 |
| 20150099885 | Nilotinib Salts And Crystalline Forms Thereof - Nilotinib salts and crystalline forms thereof have been prepared and characterized. | 04-09-2015 |
| 20150112064 | NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME - The present invention relates to a novel organic electroluminescent compound and an organic electroluminescent device comprising the same. The organic electroluminescent compound according to the present invention has high green luminous efficiency and superior material lifespan characteristics, compared with conventional phosphorescent host materials, and thus can provide an organic electroluminescent device which is excellent in operational lifespan, and induces increased power efficiency and improves power consumption. | 04-23-2015 |
| 20150322062 | P2X7 MODULATORS - The present invention is directed to compounds of Formulas (I, IIa and IIb): | 11-12-2015 |
| 20160122324 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS - The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of B-Raf. | 05-05-2016 |
| 20160130252 | POLYMORPHIC FORMS OF NILOTINIB HYDROCHLORIDE - Crystalline Forms R5, R5a, R5b and R6 of nilotinib hydrochloride and processes for their preparation. | 05-12-2016 |
| 544332000 | Chalcogen attached indirectly to the diazine ring by nonionic bonding | 24 |
| 20080281101 | Process and Intermediate Compounds Useful in the Preparation of Statins, Particularly Rosuvastatin - There is provided a process for the preparation of a compound of formula (7): formula (7) wherein R | 11-13-2008 |
| 20090036680 | SALTS OF HMG-COA REDUCTASE INHIBITORS AND USE THEREOF - The present invention relates to salts of HMG CoA reductase inhibitors, and in particular, rosuvastatin amine salts and their use as intermediates in the preparation of rosuvastatin calcium. | 02-05-2009 |
| 20090240054 | Rosuvastatin calcium with a low salt content - Provided is rosuvastatin calcium with a low salt by product content and processes for preparing such rosuvastatin calcium. | 09-24-2009 |
| 20100048899 | PROCESS FOR PREPARING ROSUVASTATIN CALCIUM - The present invention relates to an improved process for preparing Rosuvastatin calcium of Formula I. | 02-25-2010 |
| 20100069635 | ROSUVASTATIN DEHYDROABIETYLAMINE SALT - There is provided a compound, which is dehydroabietylamine salt of rosuvastatin. Also provided are processes for making rosuvastatin calcium that include formation of dehydroabietylamine salt of rosuvastatin. | 03-18-2010 |
| 20100130742 | TETRALIN AND INDANE DERIVATIVES AND USES THEREOF - Compounds of the formula I, II or III: | 05-27-2010 |
| 20110077403 | REGIOSELECTIVE PREPARATION OF SUBSTITUTED PYRIMIDINES - The present invention relates to a method of making pyrimidines of formula (III), wherein X1, X2, R1 and R2 have the meanings as defined herein. | 03-31-2011 |
| 20110190499 | SELECTIVE SYNTHESIS OF FUNCTIONALIZED PYRIMIDINES - The present invention relates to a process for making 2,4-differentiated 5-trifluoromethyl pyrimidines and 2-amino-5-trifluoromethyl-pyrimidine derivatives, which compounds are useful in the preparation of pharmacologically active compounds. | 08-04-2011 |
| 20110288299 | TRICYCLIC AMINE COMPOUND - A compound represented by the following general formula (I): | 11-24-2011 |
| 20110301349 | METHODS OF PREPARING 4-PHENYL-6-(2,2,2-TRIFLUORO-1-PHENYLETHOXY)PYRIMIDINE-BASED COMPOUNDS - Methods useful for preparing compounds of formula I: | 12-08-2011 |
| 20120041201 | METHOD FOR PRODUCING FLUORINE-CONTAINING POLYETHER CARBOXYLIC ACID AMIDE - A fluorine-containing polyether carboxylic acid amide represented by the general formula: C | 02-16-2012 |
| 20120116082 | PROCESS FOR THE PREPARATION OF ROSUVASTATIN SALTS - The present invention relates to a new process for the preparation of rosuvastatin [7-[4-(4-Fluorophenyl)-6-isopropyl-2-(methanesulphonyl-methyl-amino)-pyrimidin-5-yl]-(3R,51S)-dihydroxy-hept-6-enoic acid] of the formula (I) salts formed with bivalent cations, preferably with calcium or zinc ions, characterized in that rosuvastatin tert.-butylammonium salt is reacted with the appropriate bivalent cation, preferably with calcium or zinc ions in a mixture of a water immiscible or slightly miscible organic solvent and water and the formed salt is isolated. | 05-10-2012 |
| 20120149905 | PROCESS FOR THE MANUFACTURE OF ROSUVASTATIN CALCIUM USING CRYSTALLINE ROSUVASTATIN ETHYL ESTER - The present invention relates to an improved process to prepare Rosuvastatin calcium of Formula (I), with good quality. Further, the present invention also relates to a crystalline polymorphic form of Rosuvastatin ethyl ester. | 06-14-2012 |
| 20130079519 | REGIOSELECTIVE PREPARATION OF SUBSTITUTED PYRIMIDINES - The present invention relates to a method of making pyrimidines of formula (III) wherein X1, X2, R1 and R2 have the meanings as defined herein. | 03-28-2013 |
| 20130211085 | PROCESS FOR THE PREPARATION OF ENANTIOMERIC FORMS OF 2,3-DIAMINOPROPIONIC ACID DERIVATIVES - The disclosure relates to a process for the preparation of the enantiomeric forms of 2,3-diaminopropionic acid derivatives of formula I, | 08-15-2013 |
| 20130296563 | METHYLTETRAZOLE SULFIDES AND SULFONES - The present invention relates to a process for the preparation of a 1-methyl-1H-tetrazole-5-thio derivative comprising reaction of a halomethyl substrate with 1-methyl-H-tetrazole-5-thiol to obtain a thio-ether compound, and oxidizing the thio-ether compound to the corresponding sulfone. In case of a chiral halomethyl substrate, the resulting chiral diol sulfone derivative is suitable as a building block for statin type compounds. | 11-07-2013 |
| 20130338360 | METHOD FOR THE PREPARATION OF HIGH-PURITY PHARMACEUTICAL INTERMEDIATES - The present invention is related to intermediates useful in the preparation of pharmaceutically acceptable salts of (+)-7-[4-(4-fluorophenyl)-6-isopropyl-2-(methanesulfonyl-methyl-amino)-pyrimidin-5-yl]-(3R,5S)-dihydroxy-hept-6-enoic acid and polymorphs of said intermediates, methods for preparation thereof and use thereof. | 12-19-2013 |
| 20140128605 | CRYSTALS OF GLYCINE DERIVATIVE AND PHARMACEUTICAL USE THEREOF - A crystal of (S,E)-2-(2,6-dichlorobenzamido)-5-[4-(methyl-pyrimidin-2-ylamino)phenyl]pent-4-enoic acid has excellent chemical and physical stability, and a medical use thereof. | 05-08-2014 |
| 20140243528 | Rosuvastatin Enantiomer Compounds - The invention discloses a method for the treatment of diseases, particularly those diseases characterized by diminished or aberrant cellular function, including AIDS, cancer, and Alzheimer's Disease. The method comprises administering a therapeutically effective amount of rosuvastatin enantiomer compounds in their (3R, 5R), (3S, 5R), or (3S, 5S) configurations, or pharmaceutically acceptable salts thereof Biologically-active rosuvastatin enantiomer compounds with (3R, 5R), (3S, 5R), and (3S, 5S) stereochemistry are also disclosed. | 08-28-2014 |
| 20140371451 | Preparation of 3,5-Dioxo Hexanoate Ester in Two Steps - The invention discloses a method for the preparation of tert-butyl 6-chloro-3,5-dioxohexanoate from Meldrum's acid derivative and its use for the preparation of tert-butyl (4R,6S)-(6-hydroxymethyl-2,2-dimethyl-1,3-dioxan-4-yl)acetate (BHA), Rosuvastatin and Atorvastatin. | 12-18-2014 |
| 20150018554 | PROCESS FOR THE PREPARATION OF ENANTIOMERIC FORMS OF 2,3-DIAMINOPROPIONIC ACID DERIVATIVES - The disclosure relates to a process for the preparation of the enantiomeric forms of 2,3-diaminopropionic acid derivatives of formula I, | 01-15-2015 |
| 20150038708 | SUBSTITUTED 2-HYDROXY-4-(2-(PHENYLSULFONAMIDO)ACETAMIDO)BENZOIC ACID ANALOGS AS INHIBITORS OF STAT PROTEIN - In one aspect, the invention relates to substituted 2-hydroxy-4-(2-(phenylsulfonamido)acetamido)benzoic acid analogs, derivatives thereof, and related compounds, which are useful as inhibitors of STAT protein activity; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating disorders of uncontrolled cellular proliferation associated with a STAT protein activity dysfunction using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. | 02-05-2015 |
| 20160122349 | MORPHINAN DERIVATIVE - The present invention relates to a morphinan derivative represented by the following general formula (I), wherein R | 05-05-2016 |
| 20160185723 | C-H FLUORINATION OF HETEROCYCLES WITH SILVER (II) FLUORIDE - The present invention provides compositions and methods for the selective C—H fluorination of nitrogen-containing heteroarenes with AgF | 06-30-2016 |
