| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 544326000 | At 4- or 6-position | 30 |
| 20090054647 | Method for Preparing Substituted Pyrimidines - Disclosed a method for preparing a compound of Formula 1, | 02-26-2009 |
| 20090082567 | 2,4-PYRIMIDINEDIAMINE COMPOUNDS AND THEIR USES - The present invention provides 2,4-pyrimidinediamine compounds that inhibit the IgE and/or IgG receptor signaling cascades that lead to the release of chemical mediators, intermediates and methods of synthesizing the compounds and methods of using the compounds in a variety of contexts, including in the treatment and prevention of diseases characterized by, caused by or associated with the release of chemical mediators via degranulation and other processes effected by activation of the IgE and/or IgG receptor signaling cascades. | 03-26-2009 |
| 20100010220 | Process for Preparing Amidrazones - The present invention relates to a novel process for preparing amidrazones of the formula (I) wherein R, R | 01-14-2010 |
| 20100016591 | SYNTHESIS OF 4-AMINO-PYRIMIDINES SCAFFOLDS - Process for the manufacture of a compound of the structure (I) with R | 01-21-2010 |
| 20140350251 | HERBICIDAL PYRIMIDINES - Compounds of Formula I, and their N-oxides and agriculturally suitable salts, are disclosed which are useful for controlling undesired vegetation | 11-27-2014 |
| 20160115132 | NOVEL PHENOL DERIVATIVES AND PHARMACEUTICAL OR COSMETIC USE THEREOF - The present invention relates to novel compounds of general formula: | 04-28-2016 |
| 544327000 | Sulfur attached indirectly to the diazine ring by nonionic bonding (e.g., thiamines, etc.) | 7 |
| 20080242863 | Process For the Manufacture of a Precursor of Vitamin B1 - The present invention relates to a novel process for the manufacture of Grewe-diamine comprising the following step: hydrolyzing a compound of formula (II), | 10-02-2008 |
| 20100081812 | SUBSTITUTED PYRIMIDINE DERIVATIVES USEFUL IN THE TREATMENT OF CANCER AND OTHER DISORDERS - Substituted pyrimidine derivatives of formula (I), salts, metabolites, prodrugs and diastereoisomeric forms (both isolated stereoisomers and mixtures of stereoisomers) thereof (wherein A=pyrimidine) pharmaceutical compositions containing such compounds and the use of those compounds or compositions for treating hyper-proliferative and angiogenesis disorders, as a sole agent or in combination with other active ingredients, e.g., cytotoxic therapies. | 04-01-2010 |
| 20110178300 | NOVEL SYNTHESIS OF SUBSTITUTED 4-AMINO-PYRIMIDINES - The present invention is directed to a process for the manufacture of compounds of formula IV wherein R | 07-21-2011 |
| 20120059166 | METHODS OF USING GPR119 RECEPTOR TO IDENTIFY COMPOUNDS USEFUL FOR INCREASING BONE MASS IN AN INDIVIDUAL - The present invention relates to methods of using GPR119 receptor to identify compounds useful for increasing bone mass in an individual. Agonists of GPR119 receptor are useful as therapeutic agents for treating or preventing a condition characterized by low bone mass, such as osteoporosis, and for increasing bone mass in an individual. Agonists of GPR119 receptor promote bone formation in an individual. | 03-08-2012 |
| 20140187781 | AMINOPYRIDINES AND AMINOPYRIMIDINES USEFUL AS INHIBITORS OF PROTEIN KINASES - The present invention relates to compounds useful as inhibitors of protein kinase. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the inventions. | 07-03-2014 |
| 20140323729 | PYRUVATE KINASE M2 MODULATORS, THERAPEUTIC COMPOSITIONS AND RELATED METHODS OF USE - Compositions comprising compounds that modulate pyruvate kinase M2 (PKM2) are described herein. Also described herein are methods of using the compounds that modulate PKM2 in the treatment of cancer. | 10-30-2014 |
| 20160038486 | DRUG FOR RESPIRATORY DISEASES - It is intended to provide a therapeutic agent and/or a preventive agent for a respiratory disease or a therapeutic agent and/or a preventive agent for a sodium channel associated disease. The present invention provides a pharmaceutical comprising a compound represented by the following formula (I) or a pharmacologically acceptable salt thereof as an active ingredient: | 02-11-2016 |
| 544328000 | Additional hetero ring which is unsaturated | 13 |
| 20090198057 | Certain Chemical Entities, Compositions, and Methods - Chemical entities that modulate smooth muscle myosin and/or non-muscle myosin, pharmaceutical compositions and methods of treatment of diseases and conditions associated with smooth muscle myosin and/or non-muscle myosin are described. | 08-06-2009 |
| 20110015395 | PYRAZOLE COMPOUNDS WITH INHIBITORY ACTIVITY AGAINST ROS KINASE - Disclosed herein are novel pyrazole compounds, pharmaceutically acceptable salts thereof, a method for preparing the same, and uses thereof as anticancer agents. | 01-20-2011 |
| 20110319618 | HETEROCYCLIC COMPOUND AND USE OF THE SAME - Provided is a compound represented by general formula (6) and pharmaceutically acceptable salts thereof. (In the formula, R | 12-29-2011 |
| 20120197019 | COMPOSITIONS AND PROCESSES - Methods of making intermediates useful in the synthesis of pazopanib and compositions of such intermediates are described. | 08-02-2012 |
| 20130102782 | PROCESSES AND INTERMEDIATES FOR PRODUCING AZAINDOLES - The present invention relates to processes and intermediates for the preparation of compounds useful as inhibitors of Janus kinases (JAK). | 04-25-2013 |
| 20130303764 | PROCESSES AND INTERMEDIATES FOR PRODUCING AZAINDOLES - The present invention relates to processes and intermediates for the preparation of compounds useful as inhibitors of Janus kinases (JAK). | 11-14-2013 |
| 20130310563 | PROCESS FOR PREPARING METHYL METHYLCARBAMATE AND ITS PURIFICATION FOR USE AS PHARMACEUTICALLY ACTIVE COMPOUND - The present invention relates to a process for preparing methyl {4,6-diamino-2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-5-yl}methylcarbamate of the formula (I) | 11-21-2013 |
| 20140194625 | PREPARATION OF 2-METHYL-4-AMINO-5(SUBSTITUTED-1H-1,2,3-TRIAZOLYL)METHYLPYRIMIDINE DERIVATIVES AND MICROBICIDAL ACTIVITY THEREOF - Disclosed is a derivative of 2-methyl-4-amino-5-(substituted-1H-1,2,3-triazol)methylpyrimidine of general formula I and microbicidal activity thereof. In the formula, R1 represents hydrogen, I; X represents O or NH; Y represents phenyl of substituted phenyl, benzoyl or substituted benzoyl, phenyloxyacetyl or substituted phenyloxyacetyl; the substituents on the phenyl rings which Y involves are: H, halogen, nitro, cyano, CF3, C1˜4 alkyl, methoxyl, C1˜2 carboxyl or carboxylic ester groups; any position of phenyl rings can be mono- or multi-substituted by identical or different substituents. The compound has a significant inhibition effect on cucumber bacterial angular leaf spot, tomato bacterial leaf spot, cucumber brown blot, cucumber downy mildew, rice sheath blight, | 07-10-2014 |
| 20140288303 | PROCESS FOR PREPARING METHYL METHYLCARBAMATE AND ITS PURIFICATION FOR USE AS PHARMACEUTICALLY ACTIVE COMPOUND - The present invention relates to a process for preparing methyl {4,6-diamino-2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-5-yl}methylcarbamate of the formula (I) | 09-25-2014 |
| 20140309421 | PROCESSES AND INTERMEDIATES FOR PRODUCING AZAINDOLES - The present invention relates to processes and intermediates for the preparation of compounds useful as inhibitors of Janus kinases (JAK). | 10-16-2014 |
| 20150099884 | PROCESSES AND INTERMEDIATES FOR PRODUCING AZAINDOLES - The present invention relates to processes and intermediates for the preparation of compounds useful as inhibitors of Janus kinases (JAK). | 04-09-2015 |
| 20160168147 | ISOTOPICALLY ENRICHED AZAINDOLES | 06-16-2016 |
| 20160251354 | METHODS OF PREPARING INHIBITORS OF INFLUENZA VIRUSES REPLICATION | 09-01-2016 |
| 544329000 | Carbonyl attached directly or indirectly to the diazine ring by nonionic bonding | 4 |
| 20090137804 | Compounds and Compositions as Protein Kinase Inhibitors - The invention relates to compounds of formula (I) | 05-28-2009 |
| 20120095230 | PROCESS FOR THE PREPARATION OF PYRIMIDINE DERIVATIVES - A process for the preparation of 5-substituted 4-amino-2-methylpyrimidines of the formula (I) wherein R is CONH | 04-19-2012 |
| 20130245263 | PROCESS FOR THE PREPARATION OF PYRIMIDINE DERIVATIVES - A process for the preparation of 5-substituted 4-amino-2-methylpyrimidines of the formula | 09-19-2013 |
| 20150025238 | ARYLALKYL ESTERS OF 4-AMINO-6-(SUBSTITUTED PHENYL)-PICOLINATES AND 6-AMINO-2-(SUBSTITUTED PHENYL)-PYRIMIDINECARBOXYLATES AND THEIR USE AS SELECTIVE HERBICIDES FOR CROPS - Arylalkyl esters of 4-aminopicolinic acids and 6-amino-4-pyrimidinecarboxylates are herbicides for control of weeds especially those species common to rice and wheat cropping systems and in pasture management programs. | 01-22-2015 |
