| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 544101000 | Tricyclo ring system having the oxazine ring as one of the cyclos | 22 |
| 20080300403 | Method for Production of Quinolone-Containing Lyophilized Preparation - The present invention is directed to a lyophilized preparation which contains a synthetic quinolone antibacterial compound and, as a solo additive, a pH-adjusting agent, and which exhibits an excellent reconstituting property. The invention provides a method for producing a lyophilized preparation containing a synthetic quinolone antibacterial compound as an active ingredient, characterized by including, sequentially, cooling an aqueous solution containing a synthetic quinolone antibacterial compound and a pH-adjusting agent to yield a frozen product, elevating the temperature of the frozen product, and re-cooling the resultant to prepare the lyophilized preparation. | 12-04-2008 |
| 20090069560 | Process For Obtaining Levofloxacin Free From Salts - This invention relates to a process for obtaining levofloxacin free from salts. In this process the starting product used is the compound (V), alkaline hydrolysis of which within a water-(C | 03-12-2009 |
| 20100029937 | NOVEL AND PRACTICAL PROCESS FOR EXCLUSIVELY PRODUCING (S)-9-FLUORO-3-METHYL-10-(4-METHYL-1-PIPERAZINYL)-7-OXO-2,3-DIHYDRO-7H-PY- RIDO-[1,2,3,DE][1,4]BENZOXAZINE-6-CARBOXYLIC ACID HEMIHYDRATE - A novel and practical process for selectively producing a pyridobenzoxazine carboxylic acid hemihydrate (e.g., (S)-9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido-[1,2,3-de][1,4]benzoxazine-6-carboxylic acid hemihydrate) in high yield via crystallization from an organic solvent or a mixed organic solvent system containing a calculated amount of water released from sodium sulfate decahydrate under gradually heating. | 02-04-2010 |
| 20100029938 | PROCESS FOR THE PREPARATION OF AN ANTIBACTERIAL QUINOLONE COMPOUND - It comprises a process for the preparation of levofloxacin based on a cyclisation reaction of a compound of formula (IV), which has the alcohol group protected, followed by a deprotection reaction and the conversion of the compound obtained to levofloxacin by a process comprising a hydrolysis reaction and a second cyclisation reaction. It also comprises new intermediates compounds. | 02-04-2010 |
| 20100137583 | Peptidomimetic protease inhibitors - The present invention relates to peptidomimetic compounds useful as protease inhibitors, particularly as serine protease inhibitors and more particularly as hepatitis C NS3 protease inhibitors; intermediates thereto; their preparation including novel steroselective processes to intermediates. The invention is also directed to pharmaceutical compositions and to methods for using the compounds for inhibiting HCV protease or treating a patient suffering from an HCV infection or physiological condition related to the infection. Also provided are pharmaceutical combinations comprising, in addition to one or more HCV serine protease inhibitors, one or more interferons exhibiting anti-HCV activity and/or one or more compounds having anti HCV activity and a pharmaceutically acceptable carrier, and methods for treating or preventing a HCV infection in a patient using the compositions. The present invention is also directed to a kit or pharmaceutical pack for treating or preventing HCV infection in a patient. | 06-03-2010 |
| 20100197909 | MUTILIN DERIVATIVE HAVING HETEROCYCLIC AROMATIC RING CARBOXYLIC ACID STRUCTURE IN SUBTITUENT AT 14-POSITION - To provide a novel mutilin derivative having a substitution at the 14-position, which is a novel mutilin analogue exhibiting a potent and broad antimicrobial action against Gram-positive bacteria and Gram-negative bacteria including various drug-resistant bacteria, and which is expected to be useful as an agent for treating infectious diseases. A mutilin derivative represented by the following general formula (1): | 08-05-2010 |
| 20110137028 | METHODS OF SYNTHESIS AND PURIFICATION OF HETEROARYL COMPOUNDS - Provided herein are methods to prepare Heteroaryl Compounds having the following structure: | 06-09-2011 |
| 20120077974 | REDOX DRUG DERIVATIVES - The present invention provides redox drug derivatives. In particular, 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 1-ethyl-6-fluoro-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid, (3R,4R,5S)-4-(acetylamino)-5-amino-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylic acid ethyl ester, (3S)-3-(aminomethyl)-5-methylhexanoic acid, (3S)-1-[2-(2,3-dihydro-5-benzofuranyl)ethyl]-α-α-diphenyl-3-pyrrolidineacetamide, (1S,2S,3S,4R)-3-[(1S)-1-acetamido-2-ethyl-butyl]-4-(diaminomethylideneamino)-2-hydroxy-cyclopentane-1-carboxylic acid and (2R,3R,4S)-4-[(diaminomethylidene)amino]-3-acetamido-2-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4-dihydro-2H-pyran-6-carboxylic acid redox derivatives. | 03-29-2012 |
| 20120208998 | POLYCYCLIC CARBAMOYLPYRIDONE DERIVATIVE HAVING HIV INTEGRASE INHIBITORY ACTIVITY - A compound having an anti-viral activity, particularly a HIV integrase inhibitory activity, and a pharmaceutical composition, particularly an anti-HIV agent, of the formula: | 08-16-2012 |
| 20130245254 | METHODS OF SYNTHESIS AND PURIFICATION OF HETEROARYL COMPOUNDS - Provided herein are methods to prepare Heteroaryl Compounds having the following structure: | 09-19-2013 |
| 20130289271 | PYRAZINO[2,3-b]PYRAZINE mTOR KINASE INHIBITORS FOR ONCOLOGY INDICATIONS AND DISEASES ASSOCIATED WITH THE mTOR/PI3K/AKT PATHWAY - Provided herein are Heteroaryl Compounds having the following structure: | 10-31-2013 |
| 20140155593 | METHODS OF SYNTHESIS AND PURIFICATION OF HETEROARYL COMPOUNDS - Provided herein are methods to prepare Heteroaryl Compounds having the following structure: | 06-05-2014 |
| 20140187769 | Oxadiazoanthracene Compounds for the Treatment of Diabetes - The present invention provides methods of synthesizing oxadiazoanthracene derivatives of the formula (I) and pharmaceutically acceptable salts thereof, | 07-03-2014 |
| 20160024101 | PYRAZINO[2,3-b]PYRAZINE mTOR KINASE INHIBITORS FOR ONCOLOGY INDICATIONS AND DISEASES ASSOCIATED WITH THE mTOR/PI3K/AKT PATHWAY - Provided herein are Heteroaryl Compounds having the following structure: | 01-28-2016 |
| 544102000 | Phenoxazines (including hydrogenated) | 8 |
| 20100324285 | ANTIINFLAMMATORY AGENT COMPRISING 2-AMINOPHENOL OR DERIVATIVE THEREOF AS ACTIVE INGREDIENT - An object of the present invention is to provide anti-inflammatory agent having an excellent effect and less adverse side-effects. The object is attained by providing an anti-inflammatory agent comprising 2-aminophenol or a derivative thereof as an effective ingredient. | 12-23-2010 |
| 20110313155 | PROCESS OF MAKING 3-PHENYLIMINO-3H-PHENOXAZINE MEDIATOR - A method of forming a 3-phenylimino-3H-phenothiazine or a 3-phenylimino-3H-phenoxazine mediator includes providing a first reactant including phenothiazine or phenoxazine, providing a first solvent, providing a second reactant and providing a second solvent. The first reactant, first solvent, second reactant and second solvent are combined to form a reactants solution. Sodium persulfate is added to the reactants solution to couple the first and second reactants resulting in a reaction solution including the 3-phenylimino-3H-phenothiazine or the 3-phenylimino-3H-phenoxazine mediator. | 12-22-2011 |
| 20120035359 | PHENOXAZINE DERIVATIVES AND METHODS OF USE THEREOF - The present invention encompasses phenoxazine derivatives and methods of use thereof. | 02-09-2012 |
| 20140221647 | PHENOXAZINE DERIVATIVES AND METHODS OF USE THEREOF - The present invention encompasses phenoxazine derivatives and methods of use thereof. | 08-07-2014 |
| 20150141642 | LIGHT-EMITTING MATERIAL AND ORGANIC LIGHT-EMITTING DEVICE - A light-emitting material containing a compound represented by the following general formula in a light-emitting layer has high light emission efficiency. In the following general formula, R | 05-21-2015 |
| 20160102069 | ANTIOXIDANT HUMIC ACID DERIVATIVES AND METHODS OF PREPARATION AND USE - Disclosed are antioxidative, natural compounds, their salts, chelates and cleavage derivatives that exhibit a superior combination of properties. The compounds can be used for a variety of purposes, including stabilizing foods, cosmetics, beverages and nutritional supplement. The compounds can be prepared by substantially cleaving a humic acid of formula I to provide at least one antioxidant compounds of formula II, formula III, formula IV, formula V, formula VI, salts, or chelates thereof. | 04-14-2016 |
| 20160108010 | HUMIC ACID DERIVATIVES AND METHODS OF PREPARATION AND USE - Disclosed are antioxidative natural compounds, their salts, chelates and cleavage derivatives that exhibit a superior combination of properties. The compounds can be used for a variety of purposes, including the stabilization of polymers. The compounds can be prepared by substantially cleaving a humic acid of formula I followed by esterification to provide at least one antioxidant compounds of formula V, formula VI, formula VII, formula VIII, salts thereof, or chelates thereof. | 04-21-2016 |
| 20160380205 | LIGHT-EMITTING MATERIAL, ORGANIC LIGHT-EMITTING DEVICE, AND COMPOUND - A compound represented by the general formula (1) is useful as a light-emitting material. In the general formula (1), from 0 to 1 of R | 12-29-2016 |
