| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 544088000 | 1,3-Oxazines | 71 |
| 20090281309 | METHOD FOR PRODUCING 2-OXAZOLINE ANALOGUE OR 1,3-OXAZINE ANALOGUE - The present invention is a method for producing a 2-oxazoline analogue or a 1,3-oxazine analogue represented by the following general formula (3) by reacting a 1,2-aminoalcohol compound or a 1,2-aminothiol compound with an α,α-dihaloamine compound. | 11-12-2009 |
| 20120165521 | LOW-VOC POLYAMINO ALCOHOLS - A method for producing a polyamino-polyalcohol. The method comprises steps of: (a) combining an aminoalcohol of formula (I) | 06-28-2012 |
| 20130158260 | AMINODIHYDROTHIAZINE DERIVATIVES - A composition having BACE 1 inhibitory activity containing a compound represented by the general formula (I): | 06-20-2013 |
| 544089000 | Polycyclo ring system having the oxazine ring as one of the cyclos | 56 |
| 20100249403 | USE OF OXAZINE COMPOUNDS FOR MAKING CHROMOGENIC MATERIALS - Heterocyclic compounds incorporating a [1,3]oxazine ring may be used to make chromogenic materials. These molecules switch from a colorless state to a colored form upon addition of either acid or base. In both instances, the [1,3]oxazine ring opens in response to the pH change forming an indolium cation, after the addition of acid, or a phenolate anion, after the addition of base. Alternatively, the switch may occur in response to a change in electrical current or potential or a change in temperature. Chromophores absorb in the visible region of the electromagnetic spectrum. Hence, their formation translates into the appearance of color. These processes are fully reversible and the original colorless state can be regenerated by switching the pH back to neutral. Thus, these halochromic compounds can be used to develop displays, filters, indicators, lenses, sensors, switches, or windows able to switch their color in response to pH changes. | 09-30-2010 |
| 20110313153 | 5-HT4 INHIBITORS FOR TREATING AIRWAY DISEASES, IN PARTICULAR ASTHMA - The invention relates generally to the treatment of diseases of the respiratory system such as asthma and chronic obstructive pulmonary disease. More particularly, the present invention relates to methods of treating and preventing asthmatic airway inflammation. The treatment involves the administration of a 5-HT4 receptor antagonist to the subject in need thereof; more in particular the administration of aroylated 4-aminomethylpiperidine derivatives as defined herein. Other aspects of the invention are directed to compositions for treating or preventing respiratory disorders, including pharmaceutical compositions. | 12-22-2011 |
| 544090000 | Bicyclo ring system having the oxazine ring as one of the cyclos | 35 |
| 20100016585 | PHOSPHORUS-CONTAINING BISPHENOLS AND PREPARING METHOD THEREOF - The Phosphorus-containing bisphenols and preparing method thereof are disclosed. A method for producing the phosphorus-containing bisphenol of the general formula (1) includes reacting compounds respectively defined by a general formula (a), (b), (c) and an acid catalyst to yield compounds of phosphorus-containing bisphenol. | 01-21-2010 |
| 20140148597 | Method for Producing Benzoxazine Compounds - The present disclosure provides a method for producing a benzoxazine compound by reacting a phenolic compound with an aldehyde compound and an amine compound in the presence of a solvent system containing a apolar solvent and a polar aprotic solvent. The benzoxazine compound may be easily recovered from the solvent system to provide a benzoxazine compound in powder form that is substantially solvent-free. | 05-29-2014 |
| 544091000 | Three or more ring hetero atoms in the bicyclo ring system | 3 |
| 20110021772 | New heterocyclic compounds, their preparation and their use as medicaments, in particular as anti-bacterial agents - The invention relates to new heterocyclic compounds of general formula (I), and their salts with a base or an acid: | 01-27-2011 |
| 20110263845 | METHOD FOR MANUFACTURING HETEROCYCLE SUBSTITUTED PYRIDINE DERIVATIVES - It is an object of the present invention to provide an efficient method for manufacturing heterocycle-substituted pyridine derivatives. The present invention provides a method for manufacturing a compound represented by the following formula (I): | 10-27-2011 |
| 20140171639 | TRPM8 ANTAGONISTS AND THEIR USE IN TREATMENTS - Compounds of Formula I are useful as antagonists of TRPM8. Such compounds are useful in treating a number of TRPM8 mediated disorders and conditions and may be used to prepare medicaments and pharmaceutical compositions useful for treating such disorders and conditions. Examples of such disorders include, but are not limited to, migraines and neuropathic pain. Compounds of Formula I have the following structure: | 06-19-2014 |
| 544092000 | Chalcogen bonded directly to the oxazine ring | 30 |
| 20090306371 | CYANOPYRROLE CONTAINING CYCLIC CARBAMATE AND THIOCARBAMATE BIARYLS AND METHODS FOR PREPARING THE SAME - Methods for preparing cyclic carbamates and thiocarbamates containing cyanopyrrole moieties and of the formula are provided. | 12-10-2009 |
| 20100004439 | Heterocyclic Compound - A compound represented by the following Formula (1): | 01-07-2010 |
| 20100274007 | PROCESS FOR PREPARING POLYMORPHIC FORMS OF (S)-6-CHLORO-(CYCLOPROPYLETHYNYL)-1,4-DIHYDRO-4-(TRIFLUOROMETHYL)-2H-3,1-- BENZOXAZIN-2-ONE - Disclosed herein is a novel process for preparing polymorphic Forms of (S)-6-chloro-(cyclopropylethynyl)-1,4-di-hydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one referred as M | 10-28-2010 |
| 20110071287 | PROCESS FOR THE PREPARATION OF EFAVIRENZ - The present invention relates to a process for the preparation of Efavirenz (Formula I), wherein triphosgene is used as a cyclizing agent. | 03-24-2011 |
| 20110077397 | PROCESS FOR THE PREPARATION OF EFAVIRENZ - A simple, cost-effective process for preparation of efavirenz of formula (I) comprising reacting a solution of 5-chloro-α-(cyclopropylethynyl)-2-amino-α-trifluoromethyl) benzene methanol of formula (II) in an organic solvent with triphosgene in the presence of an inorganic base at a temperature range −5° C. to 25° C., adding water and isolating compound of formula (I). | 03-31-2011 |
| 20110124857 | ARTHROPODICIDAL ANTHRANILAMIDES - This invention provides compounds of Formula 1, their N-oxides and agriculturally suitable salts | 05-26-2011 |
| 20110196151 | PROCESS FOR THE PREPARATION OF EFAVIRENZ - The present invention is directed to a process for the preparation of Efavirenz, (4S)-6-chloro-4-(cyclopropy-lethynyl)-4-(trifluoromethyl)-1,4-dihydro-2H-3,1-benzoxazin-2-one, of formula (I) comprising reacting the intermediate of formula (II) [0045] as a free base or a salt thereof, with diphosgene (TCMCF, trichlormethylchloroformate) Cl | 08-11-2011 |
| 20110319611 | BENZOXAZINONE COMPOUND, METHOD FOR PRODUCING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME - A benzoxazinone compound having the following formula (I): | 12-29-2011 |
| 20120016118 | CYANOPYRROLE CONTAINING CYCLIC CARBAMATE AND THIOCARBAMATE BIARYLS AND METHODS FOR PREPARING THE SAME - Methods for preparing cyclic carbamates and thiocarbamates containing cyanopyrrole moieties and of the formula are provided: | 01-19-2012 |
| 20120046462 | PROCESS FOR THE SYNTHESIS OF CHIRAL CYCLIC CARBAMATES - The invention is directed to a process for the preparation of a chiral cyclic carbamate of formula | 02-23-2012 |
| 20120108809 | PROCESS FOR PREPARATION OF EFAVIRENZ - An improved process for Efavirenz, which has several advantages over reported methods like low cost, high yield, better optical purity and industrial feasibility. | 05-03-2012 |
| 20120245346 | MALEIC ACID SALT AND CRYSTAL THEREOF - Disclosed is a benz[d][1,3]oxazine derivative having excellent stability when used as an active ingredient for a medicinal agent, and also having excellent solubility and crystallinity. Specifically disclosed is 2-[2-((S)-3-dimethylaminopyrrolidin-1-yl)pyridin-3-yl]-5-ethyl-7-methoxy-4H-benz[d][1,3]oxazin-4-one maleate. | 09-27-2012 |
| 20120264933 | EFFICIENT PROCESS TO INDUCE ENANTIOSELECTIVITY IN PROCARBONYL COMPOUNDS - The present invention provides an efficient method to induce the enantioselectivity in procarbonyl compounds using chiral organometallic complexes. The present invention also provides a method for producing chiral organometallic complexes using a chiral additive, achiral additive, a base and a metal salt. | 10-18-2012 |
| 20120271047 | Novel Polymorphs of Efavirenz - The present invention relates to novel amorphous and crystalline forms of efavirenz, processes for their preparation and pharmaceutical compositions containing them. In accordance with the present invention efavirenz crude is dissolved in acetone at 25° C.-30° C., the solution is slowly added to water for 30 minutes at 0° C.-5° C., stirred for 1 hour at the same temperature, the separated solid is filtered, washed with water and dried at 55° C.-60° C. for 5 hours to give amorphous efavirenz. | 10-25-2012 |
| 20130012702 | PURIFICATION OF PROGESTERONE RECEPTOR MODULATORS - Methods for purifying a compound of formula I are provided, wherein A, B, X, Q, and R | 01-10-2013 |
| 20130165650 | PROCESS FOR THE PREPARATION OF EFAVIRENZ - A process for the preparation of Efavirenz, (4S)-6-chloro-4-(cyclopropylethynyl)-4-(trifluoromethyl)-1,4-dihydro-2H-3,1-benzoxazin-2-one, of formula (I): | 06-27-2013 |
| 20130211077 | PROCESS FOR THE SYNTHESIS OF CYCLIC CARBAMATES - The invention is directed to a process for the preparation of a cyclic carbamate starting with o-aminobenzyl alcohol and/or a suitable salt thereof, which is reacted with a cyclisation agent selected from phosgene, diphosgene, triphosgene and mixtures thereof, and in that the reaction carried out in the presence of an aqueous base, and a water-immiscible organic solvent, said organic solvent mainly comprising at least one compound selected from C | 08-15-2013 |
| 20130217875 | PROCESS FOR THE SYNTHESIS OF CYCLIC CARBAMATES - The invention is directed to a process for the preparation of a cyclic carbamate starting with a chiral propargylic alcohol and/or a suitable salt thereof, which is reacted with a cyclisation agent selected from phosgene, diphosgene, triphosgene and mixtures thereof, and in that the reaction is carried out in the presence of an aqueous base, and a water-immiscible organic solvent, said organic solvent mainly comprising at least one compound selected from C | 08-22-2013 |
| 20130317214 | METHOD FOR PRODUCING MALEATE USING WET CRYSTAL - [Problem] To efficiently (without carrying out column purification) provide a high-purity maleate having excellent storage stability, solubility, crystallinity and ease of handling according to the present invention. | 11-28-2013 |
| 20130317215 | STABLE SYNTHETIC INTERMEDIATE AND METHOD FOR MANUFACTURING SAME | 11-28-2013 |
| 20130338356 | Process for the preparation, of 2-(2-hydroxyphenyl)-benz [1, 3] oxazin-4-one and its use for preparation of 4-[3, 5-bis (2-hydroxyphenyl)-lH-l , 2, 4-triazolTl-yl] benzoic acid - The invention provides a novel process for the synthesis of 2-(2-hydroxyphenyl)-benz[1,3]oxazin-4-one, the process comprising of reacting the salicylic acid with salicylamide in the presence of p-toluenesulfonyl chloride, base and solvent. The use of 2-(2-hydroxyphenyl)-benz[1,3]oxazin-4-one in the preparation of Deferasirox is also disclosed in the invention. | 12-19-2013 |
| 20140194623 | PROCESS FOR PREPARING TETRAZOLE-SUBSTITUTED ANTHRANILIC ACID DIAMIDE DERIVATIVES BY REACTING BENZOXAZINONES WITH AMINES - The present invention relates to a process for preparing tetrazole-substituted anthranilic acid diamide derivatives of the formula (I) | 07-10-2014 |
| 20160024025 | PROCESS FOR THE PREPARATION OF DEFERASIROX - Present disclosure discloses the commercially viable process for the preparation of Deferasirox and its polymorph with. Disclosed process involves the preparation of Deferasirox via metal salt of the corresponding intermediate and deferasirox metal salt. | 01-28-2016 |
| 544093000 | Plural oxygens bonded directly to the oxazine ring | 7 |
| 20140350246 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND METHODS OF MAKING THE SAME - The present invention relates to 7-membered nitrogen-containing heterocyclic compounds and methods of making the same. Using a novel aza-[4+3] cycloaddition reaction, the 7-membered heterocyclic compounds are synthesized by reacting a first reactant and a second reactant. Exemplary first reactants and second reactants include α-halohydroxamates and dienes, respectively. | 11-27-2014 |
| 544094000 | Plural oxygens bonded directly to the oxazine ring 3,1-Benzoxazine-2,4- diones (including hydrogenated) | 6 |
| 20090247745 | AMINOQUINOLINE DERIVATIVES AND THEIR USE AS ADENOSINE A3 LIGANDS - The present invention relates to an adenosine A | 10-01-2009 |
| 20090306372 | Process for Making 3-Substituted 2-Amino-5-Halobenzamides - Disclosed is a method for preparing a compound of Formula 1 by contacting compound of Formula 2 with R | 12-10-2009 |
| 20090318688 | METHOD FOR PREPARING PHENYLALANINE DERIVATIVES HAVING QUINAZOLINE-DIONE SKELETON AND INTERMEDIATES FOR USE IN THE PREPARATION OF DERIVATIVES - A method for preparing a phenylalanine derivative having a quinazoline-dione ring represented by the following formula (1) or a pharmaceutically acceptable salt thereof, comprising the following steps (a), (b) and (c): | 12-24-2009 |
| 20110009626 | AMINOQUINOLINE DERIVATIVES AND THEIR USE AS ADENOSINE A3 LIGANDS - The present invention relates to an adenosine A | 01-13-2011 |
| 20110092700 | Novel Coumarin Derivative Having Antitumor Activity - The present invention provides a compound represented by general formula (1) below or a pharmaceutically acceptable salt thereof: | 04-21-2011 |
| 20110313154 | METHOD FOR PREPARING PHENYLALANINE DERIVATIVES HAVING QUINAZOLINE-DIONE SKELETON AND INTERMEDIATES FOR USE IN THE PREPARATION OF THE DERIVATIVES - A method for preparing a phenylalanine derivative having a quinazoline-dione ring represented by the following formula (1) or a pharmaceutically acceptable salt thereof, comprising the following steps (a), (b) and (c): | 12-22-2011 |
| 544095000 | Three or more ring hetero atoms in the polycyclo ring system | 19 |
| 20090018331 | CONDENSED IMIDAZOLE DERIVATIVES - The present invention is related to compounds represented by the following formula, or salts or hydrates thereof | 01-15-2009 |
| 20090076263 | ELIMINATION OF HETEROGENEOUS OR MIXED CELL POPULATION IN TUMORS - Methods of killing or inhibiting tumors comprising of heterogeneous or mixed cell populations is described. The killing or inhibition of tumors is achieved by selectively targeting a unique ligand suspected of being expressed on a particular cell population to also kill a cell population lacking the unique ligand. These conjugates have therapeutic use as they are delivered to a specific cell population to kill these cells and the cytotoxic drug is released to kill non-targeted cells, thereby eliminating the tumor. | 03-19-2009 |
| 20110282055 | SYNTHESIS OF CARBAMOYLPYRIDONE HIV INTEGRASE INHIBITORS AND INTERMEDIATES - A synthesis approach providing an early ring attachment via a bromination to compound 1-1 yielding compound II-II whereby a final product such as AA can be synthesized. In particular, the 2,4-difluorophenyl-containing sidechain is attached before creation of the additional ring Q. | 11-17-2011 |
| 20110319612 | ELIMINATION OF HETEROGENEOUS OR MIXED CELL POPULATION IN TUMORS - Methods of killing or inhibiting tumors comprising of heterogeneous or mixed cell populations is described. The killing or inhibition of tumors is achieved by selectively targeting a unique ligand suspected of being expressed on a particular cell population to also kill a cell population lacking the unique ligand. These conjugates have therapeutic use as they are delivered to a specific cell population to kill these cells and the cytotoxic drug is released to kill non-targeted cells, thereby eliminating the tumor. | 12-29-2011 |
| 20120022251 | METHOD OF PRODUCING PYRONE AND PYRIDONE DERIVATIVES - The present invention provides a pyrone derivative and a pyridone derivative, which are novel intermediates for synthesizing an anti-influenza drug, a method of producing the same, and a method of using the same. | 01-26-2012 |
| 20130172551 | Process for Preparing Carbamolypyridone Derivatives and Intermediates - The present invention relates to the preparation of carbamoylpyridone derivatives and intermediates. | 07-04-2013 |
| 20140011995 | Process for Preparing Compound Having HIV Integrase Inhibitory Activity - A process for preparing a compound represented by formula (Y1) or (Y2) [wherein R | 01-09-2014 |
| 20140243521 | SYNTHESIS OF CARBAMOYLPYRIDONE HIV INTEGRASE INHIBITORS AND INTERMEDIATES - A synthesis approach providing an early ring attachment via a bromination to compound 1-1 yielding compound II-I1, whereby a final product such as AA can be synthesized. In particular, the 2,4-difluorophenyl-containing sidechain is attached before creation of the additional ring Q. | 08-28-2014 |
| 20140256937 | POLYCYCLIC PYRIDONE DERIVATIVE HAVING INTEGRASE INHIBITORY ACTIVITY - The present invention relates to a novel compound having an antiviral effect, more specifically, a pyridone derivative having HIV integrase inhibitory activity, and a medicament containing the same, in particular, an anti-HIV agent. The compound of the present invention has integrase inhibitory activity and/or cell proliferation inhibitory activity against viruses, in particular, HIV and drug-resistant strains thereof. Thus, the compound is useful in preventing or treating various diseases, viral infections (for example, AIDS), and the like in which integrase participates. | 09-11-2014 |
| 20150031876 | METHOD FOR PRODUCING PYRONE AND PYRIDONE DERIVATIVES - The present invention provides a pyrone derivative and a pyridone derivative, which are novel intermediates for synthesizing an anti-influenza drug, a method of producing the same, and a method of using the same. | 01-29-2015 |
| 20150038702 | Method of producing compounds having HIV integrase inhivitory activity - A process for preparing a compound represented by formula (Y1) or (Y2) | 02-05-2015 |
| 20150057444 | Process for Preparing Pyridinone Carboxylic Acid Aldehydes - The present invention relates to the preparation of carbamoylpyridone derivatives and intermediates. | 02-26-2015 |
| 20150105551 | OXIDATIVE DEGRADATION PRODUCTS OF ATROVASTATIN CALCIUM - The present invention relates to oxidative degradation products of atorvastatin calcium and the process of the preparation thereof. The present invention also relates to atorvastatin calcium substantially free of oxidative degradation products and the pharmaceutical compositions containing such atorvastatin calcium. | 04-16-2015 |
| 20150329559 | PROCESS FOR PREPARING (4R,12aS)-N-(2,4-DIFLUOROBENZYL)-7-METHOXY-4-METHYL-6,8-DIOXO-3,4,6,8,12,- 12A-HEXAHYDRO-2H-PYRIDO[1',2':4,5]PYRAZINO[2,1-b][1,3]OXAZINE-9-CARBOXAMID- E - The present invention relates to processes for the preparation of the compound VIIa: | 11-19-2015 |
| 20150368264 | SYNTHESIS OF POLYCYCLIC-CARBAMOYLPYRIDONE COMPOUNDS - Methods of making compounds of Formula I are disclosed: | 12-24-2015 |
| 20160031902 | NOVEL MAYTANSINOID DERIVATIVES WITH SULFOXIDE LINKER - The invention relates to novel maytansinoid compounds having sulfoxide linkers and more specifically to novel maytansinoid compounds of structural formula (I) and (II). The invention also provides conjugates of the maytansinoid compounds linked to a cell-binding agent. The invention further provides compositions and methods useful for inhibiting abnormal cell growth or treating a proliferative disorder in a mammal using the compounds or conjugates of the invention. | 02-04-2016 |
| 20160060274 | SYNTHESIS OF CARBAMOYLPYRIDONE HIV INTEGRASE INHIBITORS AND INTERMEDIATES - A synthesis approach providing an early ring attachment via a bromination to compound l-l yielding compound II-Il, whereby a final product such as AA can be synthesized. In particular, the 2,4-difluorophenyl-containing sidechain is attached before creation of the additional ring Q. | 03-03-2016 |
| 20160108058 | An improved process for the preparation of Dolutegravir - The present invention provides (R)-3-Amino-1-butanol (D)-tartarate (IIb); process for its preparation and its conversion to Dolutegravir. The present invention also provides an improved process for the preparation of Dolutegravir (I) or pharmaceutically acceptable salts wherein compound (XVI) is reacted with an optically active acid addition salt of (R)-3-amino-1-butanol (IIa). | 04-21-2016 |
| 20180022757 | SYNTHESIS OF POLYCYCLIC-CARBAMOYLPYRIDONE COMPOUNDS | 01-25-2018 |
| 544096000 | Additional hetero ring containing | 3 |
| 20110269957 | SYNTHESIS OF INHIBITORS OF 11BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 - Disclosed are syntheses of 11β-HSD1 inhibitors and corresponding intermediates that are promising for the treatment of a variety of disease states including diabetes, metabolic syndrome, obesity, glucose intolerance, insulin resistance, hyperglycemia, hypertension, hypertension-related cardiovascular disorders, hyperlipidemia, deleterious gluco-corticoid effects on neuronal function (e.g. cognitive impairment, dementia, and/or depression), elevated intra-ocular pressure, various forms of bone disease (e.g., osteoporosis), tuberculosis, leprosy (Hansen's disease), psoriasis, and impaired wound healing (e.g., in patients that exhibit impaired glucose tolerance and/or type 2 diabetes). | 11-03-2011 |
| 20130203985 | 2-OXO-1,2-DIHYDROPYRIDIN-4-YLBORONIC ACID DERIVATIVES - The present invention relates to a compound of formula (I) wherein R | 08-08-2013 |
| 20140135493 | METHODS OF MAKING DIASTEREOMERIC ORGANIC COMPOUNDS - Disclosed is a process for making diastereomeric compound of the formula (I): wherein m, n and R | 05-15-2014 |
| 544097000 | Chalcogen bonded directly to the oxazine ring | 9 |
| 20090187017 | PROCESS FOR PREPARING ENANTIOMERICALLY ENRICHED BETA-AMINO ACID DERIVATIVES - The present invention relates to a process for the organo-catalysed kinetic racemate resolution of compounds of the general formula (II). It is thus possible through the action of catalytic amounts of enantiomerically enriched compounds of the general formula (Ia) or (Ib) to obtain on the one hand enantiomerically enriched optionally N-acylated β-amino acid esters and on the other hand enantiomerically enriched 4,5-dihydrooxazin-6-ones (oxazinones). The corresponding enantiomerically enriched β-amino acids can be formed from both easily separable classes of compounds by simple hydrolysis. | 07-23-2009 |
| 20100280242 | Method of Preparing Cyclic Carbonates, Cyclic Carbamates, Cyclic Ureas, Cyclic Thiocarbonates, Cyclic Thiocarbamates, and Cyclic Dithiocarbonates - A method of preparing a cyclic monomer, comprising: forming a first mixture comprising a precursor compound, bis(pentafluorophenyl) carbonate, and a catalyst; wherein the precursor compound has a structure comprising a) two or more carbons, and b) two functional groups selected from the group consisting of primary amine, secondary amine, thiol group, hydroxyl group, and combinations thereof; and agitating the first mixture at a temperature effective to form a second mixture comprising the cyclic monomer, the cyclic monomer selected from the group consisting of a cyclic carbonate, a cyclic carbamate, a cyclic urea, a cyclic thiocarbonate, a cyclic thiocarbamate, and a cyclic dithiocarbonate. | 11-04-2010 |
| 20110172419 | PROCESS FOR THE SYNTHESIS OF CYCLIC CARBAMATES - The invention is directed to a process for the preparation of cyclic carbamates of formula | 07-14-2011 |
| 20110224430 | PREPARATION OF METHIONINE OR SELENOMETHIONINE FROM HOMOSERINE VIA A CARBAMATE INTERMEDIATE - Provided herein are processes for the production of methionine or selenomethionine from homoserine. In particular, the processes proceed via the production of carbamate intermediates. | 09-15-2011 |
| 20120178925 | POLYMERS BEARING PENDANT PENTAFLUOROPHENYL ESTER GROUPS, AND METHODS OF SYNTHESIS AND FUNCTIONALIZATION THEREOF - A one pot method of preparing cyclic carbonyl compounds comprising an active pendant pentafluorophenyl ester group is disclosed. The cyclic carbonyl compounds can be polymerized by ring opening methods to form ROP polymers comprising repeat units comprising a side chain pentafluorophenyl ester group. Using a suitable nucleophile, the pendant pentafluorophenyl ester group can be selectively transformed into a variety of other functional groups before or after the ring opening polymerization. | 07-12-2012 |
| 20120202993 | METHOD OF PREPARING CYCLIC CARBONATES, CYCLIC CARBAMATES, CYCLIC UREAS, CYCLIC THIOCARBONATES, CYCLIC THIOCARBAMATES, AND CYCLIC DITHIOCARBONATES - A method of preparing a cyclic monomer, comprising: forming a first mixture comprising a precursor compound, bis(pentafluorophenyl)carbonate, and a catalyst; wherein the precursor compound has a structure comprising a) two or more carbons, and b) two functional groups selected from the group consisting of primary amine, secondary amine, thiol group, hydroxyl group, and combinations thereof; and agitating the first mixture at a temperature effective to form a second mixture comprising the cyclic monomer, the cyclic monomer selected from the group consisting of a cyclic carbonate, a cyclic carbamate, a cyclic urea, a cyclic thiocarbonate, a cyclic thiocarbamate, and a cyclic dithiocarbonate. | 08-09-2012 |
| 20130211078 | PREPARATION OF METHIONINE OR SELENOMETHIONINE FROM HOMOSERINE VIA A CARBAMATE INTERMEDIATE - Provided herein are processes for the production of methionine or selenomethionine from homoserine. In particular, the processes proceed via the production of carbamate intermediates. | 08-15-2013 |
| 20130237701 | METHOD OF PREPARING CYCLIC CARBONATES, CYCLIC CARBAMATES, CYCLIC UREAS, CYCLIC THIOCARBONATES, CYCLIC THIOCARBAMATES, AND CYCLIC DITHIOCARBONATES - A method of preparing a cyclic monomer, comprising: forming a first mixture comprising a precursor compound, bis(pentafluorophenyl)carbonate, and a catalyst; wherein the precursor compound has a structure comprising a) two or more carbons, and b) two functional groups selected from the group consisting of primary amine, secondary amine, thiol group, hydroxyl group, and combinations thereof; and agitating the first mixture at a temperature effective to form a second mixture comprising the cyclic monomer, the cyclic monomer selected from the group consisting of a cyclic carbonate, a cyclic carbamate, a cyclic urea, a cyclic thiocarbonate, a cyclic thiocarbamate, and a cyclic dithiocarbonate. | 09-12-2013 |
| 20150112060 | Multifunctional composition base 1,3-oxazinan-6-ones with corrosion inhibition and heavy organic compounds inhibition and dispersants and obtaining process - Base compounds including 1,3-oxazinan-6-one derivatives of N-alkyl or N-alkenyl or N-cycloalkyl or N-aryl propionic acids and paraformaldehyde, and their application as corrosion inhibitors with multifunctional properties serving as inhibitory/dispersant of asphaltene in production processes, transportation, refining and storage of crude oil and derivatives. The corrosion inhibitor with inhibitory/dispersant of asphaltenes properties comprises an active substance base of 1,3-oxaninan-6-ones and hydrocarbon solvents such as benzene, toluene, mixed xylenes, o-xylene, m-xylene and p -xylene, diesel, kerosene, jet fuel, alcohols, aliphatic branched and unbranched alcohols containing from 3 to 10 carbon atoms, such as isopropanol, butanol and pentanol, and mixtures of hydrocarbon solvents with aliphatic branched or unbranched liquid fuels. In addition, a process for obtaining 1,3-oxazinan-6-ones derivatives of N-alkyl or N-alkenyl or N-cycloalkyl or N-aryl propionic acids and paraformaldehyde is described. | 04-23-2015 |
