| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 544070000 | Spiro | 14 |
| 20090299061 | FLUORESCENCE ASSAYS WITH IMPROVED SENSITIVITY - Latent fluorescent compounds, comprising a fluorescent molecule with one or more blocking groups attached and optionally one or more urea-containing groups are provided. The urea-containing group can be used to further attach one or more molecules of interest, such as proteins, peptides or nucleic acids. The blocking group(s) is released from the latent fluorescent compound by reaction with a trigger, forming the fluorescent molecule which can be detected. Also provided herein are methods of using latent fluorescent compounds to detect triggers. | 12-03-2009 |
| 20100210837 | PACTAMYCIN BIOSYNTHETIC GENE CLUSTER - This disclosure describes the molecular cloning of a pactamycin biosynthetic gene cluster from | 08-19-2010 |
| 20100267947 | EXO-SELECTIVE SYNTHESIS OF HIMBACINE ANALOGS - This application discloses a novel process for the synthesis of himbacine analogs, as well as the compounds produced thereby. The synthesis proceeds by alternative routes including the cyclic ketal amide route, the chiral carbamate amide route, and the chiral carbamate ester route. The compounds produced thereby are useful as thrombin receptor antagonists. The chemistry disclosed herein is exemplified in the following synthesis sequence: | 10-21-2010 |
| 20120142914 | EXO-SELECTIVE SYNTHESIS OF HIMBACINE ANALOGS - This application discloses a novel process for the synthesis of himbacine analogs, as well as the compounds produced thereby. The synthesis proceeds by alternative routes including the cyclic ketal amide route, the chiral carbamate amide route, and the chiral carbamate ester route. The compounds produced thereby are useful as thrombin receptor antagonists. The chemistry disclosed herein is exemplified in the following synthesis sequence: | 06-07-2012 |
| 20120302745 | EXO-SELECTIVE SYNTHESIS OF HIMBACINE ANALOGS - This application discloses a novel process for the synthesis of himbacine analogs, as well as the compounds produced thereby. The synthesis proceeds by alternative routes including the cyclic ketal amide route, the chiral carbamate amide route, and the chiral carbamate ester route. The compounds produced thereby are useful as thrombin receptor antagonists. The chemistry disclosed herein is exemplified in the following synthesis sequence: | 11-29-2012 |
| 20130096301 | KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME - The present invention is directed to novel synthetic methods for preparing a spiro cyclopropyl indolinone compound represented by Structural Formula (A): (A) or its pharmaceutically acceptable salt thereof. Also included are synthetic intermediates described herein. | 04-18-2013 |
| 20140256935 | 5,6-RING-SUBSTITUTED NAPHTHOPYRAN COMPOUNDS - The present invention relates to naphthopyran compounds that include at least one compound represented by the following Formulas (I), (II), and (III): | 09-11-2014 |
| 20140378680 | SPIRO-OXINDOLE MDM2 ANTAGONISTS - Provided herein are compounds, compositions, and methods in the field of medicinal chemistry. The compounds and compositions provided herein relate to spiro-oxindoles which function as antagonists of the interaction between p53 and MDM2, and their use as therapeutics for the treatment of cancer and other diseases. | 12-25-2014 |
| 544071000 | Spiro oxazine | 6 |
| 20090143577 | PURIFICATION OF PROGESTERONE RECEPTOR MODULATORS - Methods for purifying a compound of formula I are provided, wherein A, B, X, Q, and R | 06-04-2009 |
| 20100228025 | STRUCTURED ORGANIC FILMS HAVING AN ADDED FUNCTIONALITY - A structured organic film with an added functionality comprising a plurality of segments and a plurality of linkers arranged as a covalent organic framework, wherein the structured organic film may be a multi-segment thick structured organic film. | 09-09-2010 |
| 20140364601 | PROCESS - Processes for the preparation of the compound of formula (II) and intermediate compounds for use in the processes. | 12-11-2014 |
| 20150291623 | SPIRO-OXINDOLE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS - This invention is directed to spiro-oxindole compounds, as stereoisomers, enantiomers, tautomers thereof or mixtures thereof; or pharmaceutically acceptable salts, solvates or prodrugs thereof, for the treatment and/or prevention of sodium channel-mediated diseases or conditions, such as pain. | 10-15-2015 |
| 20160002261 | Process - Processes for the preparation of the compound of formula II | 01-07-2016 |
| 20160115179 | SPIRO-OXAZINES, INDOLINONES AND PREPARATION THEREOF - The present invention relates to novel spiro-oxazine analogues of Formula-I and Indolinone compounds of Formula-II or positional isomers, or stereoisomers, or derivatives, or pharmaceutically acceptable salt thereof. Formula-I Formula-II Further the invention provides transition-metal free multicomponent reaction (MCR) process for the preparation of said compounds of Formula-I and II using aryne precursor, N-substituted isatin and N-heteroaromatic compound as the nucleophile, under mild condition leading to formation of desired complex of spiro-oxazine analogues (I) and indolinone analogues (II) in high yield and selectivity. | 04-28-2016 |
