| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 544056000 | 1,4-thiazines | 56 |
| 544580100 | Double bonded divalent chalcogen containing | 40 |
| 20110124856 | AMINOPROPYLIDENE DERIVATIVE - An aminopropylidene derivative having excellent histamine receptor antagonistic action, a compound which is useful as a pharmaceutical composition, especially as an active ingredient, having alleviated side effects in the central nervous system is described. In the aminopropylidene derivative, R | 05-26-2011 |
| 20160039847 | Arginase Inhibitors and Methods of Use Thereof - The present invention includes arginase enzyme inhibitors, compositions comprising these arginase inhibitors, and methods of treating or diagnosing conditions characterized either by abnormally high arginase activity or abnormally low nitric oxide levels in a mammal, comprising administering compositions of the invention to the mammal. | 02-11-2016 |
| 544580200 | Divalent chalcogen double bonded directly to the thiazine ring | 32 |
| 20080287676 | FUSED COMPOUNDS THAT INHIBIT VANILLOID RECEPTOR SUBTYPE 1 (VR1) RECEPTOR - The present invention discloses novel compounds of general formula (I) | 11-20-2008 |
| 20090326220 | Tetrazole-Substituted Arylamides as P2X3 and P2X2/3 Antagonists - Compounds of the formula I: | 12-31-2009 |
| 20100145041 | Thiazolyl-dihydro-quinazoline compounds and processes for preparing same - Disclosed are thiazolyl-dihydro-quinazolines of general formula (I) | 06-10-2010 |
| 20100168419 | Diacylglycerol Acyltransferase Inhibitors - Provided herein are compounds of the formula (I): | 07-01-2010 |
| 20100234591 | BIARYL HETEROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME - The present invention relates generally to the field of anti-infective, anti-proliferative, anti-inflammatory, and prokinetic agents. More particularly, the invention relates to a family of compounds having both a biaryl moiety and at least one heterocylic moiety that are useful as such agents. | 09-16-2010 |
| 20100324284 | PYRROLOPYRIMIDINE DERIVATIVE AS P13K INHIBITOR AND USE THEREOF - A preventive or therapeutic agent of a proliferative disease such as cancer, having superior PI3K inhibitory effects, superior cell proliferation inhibitory action as well as superior stability in a body and water solubility, is provided. | 12-23-2010 |
| 20110009625 | NOVEL COMPOUNDS - Novel substituted 2,4,8-trisubstituted-8H-pyrido[2,3-d]pyrimidin-7-one compounds and compositions for use in therapy as CSBP/p38 kinase inhibitors. | 01-13-2011 |
| 20110034689 | N4-Phenyl-Quinazoline-4-Amine Derivatives and Related Compounds as ErbB Type I Receptor Tyrosine Kinase Inhibitors for the Treatment of Hyperproliferative Diseases - This invention provides compounds of Formula I | 02-10-2011 |
| 20110269953 | Nitrogen and Sulfur-Containing Heterocycle Derivatives - The present invention provides nitrogen and sulfur-containing heterocycle compounds to be used as scaffolds and, in particular, nitrogen and sulfur-containing heterocycle compounds having a thiomorpholine core. The compounds herein described may be useful in treating diseases such as diabetes, obesity, cancer, cardiovascular, Alzheimer's, inflammatory, antidepressant, rheumatoid arthritis, multiple sclerosis, allergic rhinitis, asthma as well as viral and bacterial infections. The compounds herein described may also be useful in treating CNS disorders such as but not limited to Schizophrenia, Alzheimer's disease (AD). | 11-03-2011 |
| 20110269954 | NOVEL THIAZOLIDINEDIONE DERIVATIVE AND USE THEREOF - The present invention relates to novel thiazolidinedione derivatives expressed by the following formula (I) and the uses thereof. More specifically, the present invention relates to novel thiazolidinedione derivatives expressed by the following formula (I) and a pharmaceutical composition comprising the same. The novel thiazolidinedione derivatives of formula (I) according to the present invention can be effectively used for the prevention or treatment of cardiovascular disease, gastrointestinal disease and renal disease by inhibiting the activity of 15-hydroxyprostaglandin dehydrogenase (15-PGDH) that decomposes prostaglandins as well as useful for the prevention of hair loss and the stimulation of hair growth, and osteogenic stimulation and wound healing. | 11-03-2011 |
| 20110313151 | ANELLATED PYRIDINE COMPOUNDS - The present invention is concerned with novel dual modulators of the 5-HT | 12-22-2011 |
| 20120123114 | QUINAZOLINE DERIVATIVES HAVING TYROSINE KINASE INHIBITORY ACTIVITY - A compound which inhibits both of EGF receptor tyrosine kinase and HER2 tyrosine kinase is provided. | 05-17-2012 |
| 20120202992 | PYRAZOLO[1,5-A] PYRIMIDINE COMPOUNDS AS CB1 RECEPTOR ANTAGONIST - Pyrazolo[1,5-a]pyrimidine compound, having CB1 receptor-antagonizing activity, of formula [I]: | 08-09-2012 |
| 20120214991 | Indenone Derivative and Pharmaceutical Composition Comprising Same - An indenone derivative of formula (1) is effective in enhancing the activity of osteoblastic cells and inhibiting bone resorption by osteoclastic cells, and a pharmaceutical composition comprising the indenone derivative or a pharmaceutically acceptable salt thereof is useful for preventing or treating bone diseases such as osteoporosis. | 08-23-2012 |
| 20120220766 | TETRAHYDRO-IMIDAZO[1,5-alpha] PYRAZINE DERIVATIVES, PREPERATION PROCESS AND MEDICINAL USE THEREOF - Tetrahydro-imidazo[1,5-a]pyrazine derivatives of formula (I), their preparation methods, pharmaceutical compositions containing the derivatives and uses thereof as medicaments, especially as dipeptidyl peptidase IV inhibitors, wherein the substituents of formula (I) are defined as same as the description. | 08-30-2012 |
| 20130072679 | DIHYDROQUINOLINE-2-ONE DERIVATIVES - The invention provides novel compounds having the general formula (I) | 03-21-2013 |
| 20130102778 | PROCESS FOR THE PREPARATION OF ISOXAZOLYL- METHOXY NICOTINIC ACIDS - The present invention relates to a process for the preparation of a compound of formula (I) | 04-25-2013 |
| 20130211076 | Method for preparing substituted N-(3-amino-quinoxalin-2-yl)-sulfonamides and their intermediates N-(3-chloro-quinoxalin-2-yl)-sulfonamides - The present invention provides a new synthesis for preparing N-(3-amino-quinoxalin-2-yl)-sulfonamides of general formulae (I) or (I′) and intermediates sulfonamides of formula (II) or (II′): | 08-15-2013 |
| 20130274467 | ISOXAZOLO-PYRIDINE DERIVATIVES - The present invention is concerned with isoxazole-pyridine derivatives of formula I | 10-17-2013 |
| 20130274468 | ISOXAZOLO-PYRIDINE DERIVATIVES - The present invention is concerned with isoxazole-pyridine derivatives of formula I | 10-17-2013 |
| 20130274469 | ISOXAZOLO-PYRIDINE DERIVATIVES - The present invention is concerned with isoxazole-pyridine derivatives of formula I | 10-17-2013 |
| 20130324717 | COPOLYMERIZABLE METHINE AND ANTHRAQUINONE COMPOUNDS AND ARTICLES CONTAINING THEM - This invention relates to polymerizable ultraviolet light absorbers and yellow colorants and their use in ophthalmic lenses. In particular, this invention relates to polymerizable ultraviolet light absorbing methane compounds and yellow compounds of the methine and anthraquinone classes that block ultraviolet light and/or violet-blue light transmission through ophthalmic lenses. | 12-05-2013 |
| 20140142302 | 1,5-NAPHTHYRIDINE DERIVATIVE OR SALT THEREOF - A 1,5-naphthyridine derivative represented by Formula [1] (in which R | 05-22-2014 |
| 20150080568 | COMPOUNDS USEFUL AS RAF KINASE INHIBITORS - The present invention provides compounds useful as inhibitors of Raf protein kinase. The present invention also provides compositions thereof, and methods of treating Raf-mediated diseases. | 03-19-2015 |
| 20160046630 | PERIPHERALLY RESTRICTED DIPHENYL PURINE DERIVATIVES - The invention provides compounds capable of acting as antagonists at cannabanoid receptors according to the following formula: | 02-18-2016 |
| 20160060214 | POLYMERIZABLE COMPOSITION COMPRISING AN OXIME SULFONATE AS THERMAL CURING AGENT - The present invention relates to a polymerizable composition comprising at least one ethylenically unsaturated, polymerizable compound and at least one oxime sulfonate compound of the formula I | 03-03-2016 |
| 20160060222 | AMINO-QUINOLINES AS KINASE INHIBITORS - Disclosed are quinoline compounds having the formula: | 03-03-2016 |
| 20160068523 | Benzene Sulfonamide Thiazole and Oxazole Compounds - The present invention provides thiazole sulfonamide and oxazole sulfonamide compounds, compositions containing the same, as well as processes for the preparation and methods for their use as pharmaceutical agents. | 03-10-2016 |
| 20160075703 | SUBSTITUTED AZAINDOLEOXOACETIC PIPERAZINE DERIVATIVES - This invention provides compounds having drug and bio-affecting properties, their pharmaceutical compositions and method of use. In particular, the invention is concerned with azaindoleoxoacetyl piperazine derivatives having the Formula I: | 03-17-2016 |
| 20160102102 | TRICYCLIC HETEROCYCLIC COMPOUNDS AND JAK INHIBITORS - This disclosure relates to novel tricyclic pyrimidine compounds and tricyclic pyridine compounds having JAK inhibitory activities. A tricyclic heterocyclic compound represented by the formula (I | 04-14-2016 |
| 20160194311 | SUBSTITUTED NICOTINAMIDE DERIVATIVES AS KINASE INHIBITORS | 07-07-2016 |
| 20160251357 | Method of Treatment Using Substituted Imidazo[1,2b]Pyridazine Compounds | 09-01-2016 |
| 544580400 | Having -C(=X)-, wherein X is chalcogen, bonded directly to the thiazine ring | 2 |
| 20090198052 | METHOD FOR PREPARING OPTICALLY ACTIVE PIPERIDINE COMPOUNDS - The present invention relates to a method for preparing a syn-form piperidine compound represented by general formula [I]: | 08-06-2009 |
| 20150073139 | Pesticidal Arylpyrrolidines - The invention is directed to arylpyrrolidines compounds which exhibit excellent insecticidal efficacy and which may be used as in the agrochemical field or in the vield of veterinary medicine. The compounds are represented by formula (I): | 03-12-2015 |
| 544580500 | Additional hetero ring containing | 4 |
| 20100222576 | 2-Oxo-1-pyrrolidine derivatives, processes for preparing them and their uses - The invention concerns 2-oxo- | 09-02-2010 |
| 544580600 | Ring nitrogen in the additional hetero ring, which is six-membered | 2 |
| 20110152518 | Cycloalkyl Substituted Pyrimidinediamine Compounds And Their Uses - The present disclosure provides 2,4-pyrimidinediamine compounds having antiproliferative activity, compositions comprising the compounds and methods of using the compounds to inhibit cellular proliferation and to treat proliferate diseases such as tumorigenic cancers. | 06-23-2011 |
| 20120197013 | SIRTUIN MODULATING COMPOUNDS - Provided herein are novel sirtuin-modulating compounds and methods of use thereof. The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, and/or flushing as well as diseases or disorders that would benefit from increased mitochondrial activity. Also provided are compositions comprising a sirtuin-modulating compound in combination with another therapeutic agent. | 08-02-2012 |
| 544580700 | Ring chalcogen in the additional hetero ring | 1 |
| 20100240889 | Urea Derivatives Methods For Their Manufacture And Uses Thereof - The present invention provides compounds of formula (I): in which R | 09-23-2010 |
| 544059000 | Thiomorpholines (i.e., fully hydrogenated 1,4-thiazines) | 16 |
| 20160108064 | AMINO(BROMO)SILANE PRECURSORS FOR ALD/CVD SILICON-CONTAINING FILM APPLICATIONS AND METHODS OF USING THE SAME - Disclosed are Si-containing film forming compositions, methods of synthesizing the same, and methods of using the same to deposit silicon-containing films using vapor deposition processes. The disclosed Si-containing film forming composition comprising an amino(bromo)silane precursor having the formula: | 04-21-2016 |
| 544060000 | Additional hetero ring containing | 15 |
| 20090054642 | NOVEL BENZAMIDINE DERIVATIVE, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING SAME - The present invention relates to a novel benzamidine derivative, a process for the preparation thereof, and a pharmaceutical composition comprising the same. The benzamidine derivative of the present invention effectively inhibits osteoclast differentiation at an extremely low concentration, and greatly increases the trabecular bone volume, and thus it can be advantageously used for the prevention and treatment of osteoporosis. | 02-26-2009 |
| 20090062531 | Arylacetate Derivatives Having Isoxazole Skeleton - A compound of the formula (I): | 03-05-2009 |
| 20100249402 | NOVEL BENZAMIDINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING OSTEPOROSIS COMPRISING THE SAME - The present invention relates to novel benzamidine derivatives, a process for the preparation thereof and a pharmaceutical composition for preventing or treating osteoporosis comprising the same. The benzamidine derivatives of the present invention effectively inhibit osteoclast differentiation at an extremely low concentration, and thus can be advantageously used for the prevention and treatment of osteoporosis. | 09-30-2010 |
| 20100298558 | SUBSTITUTED DIHYDROAZOLE COMPOUND AND PEST CONTROL AGENT - There is provided a novel pest control agent, particularly an insecticide or miticide. A substituted dihydroazole compound of General Formula (1) or a salt thereof: | 11-25-2010 |
| 20110207926 | NOVEL DIHYDROTRIAZINE DERIVATIVE - A compound represented by formula (1), | 08-25-2011 |
| 20120059163 | Non-linear opticaly active molecules, their synthesis, and use - In one aspect, the present invention provides a hyperpolarizable organic chromophore. The chromophore is a nonlinear optically active compound that includes a π-donor conjugated to a π-acceptor through a π-electron conjugated bridge. In other aspects of the invention, donor structures and acceptor structures are provided. In another aspect of the invention, a chromophore-containing polymer is provided. In one embodiment, the chromophore is physically incorporated into the polymer to provide a composite. In another embodiment, the chromophore is covalently bonded to the polymer, either as a side chain polymer or through crosslinking into the polymer. In other aspects, the present invention also provides a method for making the chromophore, a method for making the chromophore-containing polymer, and methods for using the chromophore and chromophore-containing polymer. | 03-08-2012 |
| 20120123115 | CYCLIC GUANIDINE IONIC LIQUID - Disclosed is an ionic liquid which is stable over a wide potential range and exhibits a high ionic conductivity. The ionic liquid comprises a cyclic guanidine salt represented by the following formula (1): | 05-17-2012 |
| 20130123492 | ACENAPHTHO HETEROCYCLIC COMPOUND AND APPLICATION THEREOF - The present invention relates to acenaphtho heterocyclic compounds and their uses in manufacturing the BH3 mimetics as Bcl-2-like protein inhibitors. Structures are shown in the following: | 05-16-2013 |
| 20130144055 | Benzene Sulfonamide Thiazole And Oxazole Compounds - The present invention provides thiazole sulfonamide and oxazole sulfonamide compounds, compositions containing the same, as well as processes for the preparation and methods for their use as pharmaceutical agents. | 06-06-2013 |
| 20130281690 | ISOXAZOLO-PYRIDINE DERIVATIVES - The present invention is concerned with isoxazole-pyridine derivatives of formula I | 10-24-2013 |
| 544061000 | The additional hetero ring is one of the cyclos in a bicyclo ring system | 5 |
| 20100036118 | Fused Ring Heterocycle Kinase Modulators - The present invention provides novel fused ring heterocycle kinase modulators and methods of using the novel fused ring heterocycle kinase modulators to treat diseases mediated by kinase activity. | 02-11-2010 |
| 20140330008 | PROCESS FOR THE PREPARATION OF BORONIC ACID INTERMEDIATES - The present invention relates to a process for the preparation of 2-amino-pyrimidine-5-boronic acid of formula (I). | 11-06-2014 |
| 544062000 | Benzo is the other cyclo | 3 |
| 20090054643 | NOVEL METHOD OF SYNTHESIS OF FLUOROQUINOLONES - The invention relates to a method of preparation of fluoroquinolones of formula (I) from compounds of formula (II): | 02-26-2009 |
| 20090118499 | 6,6-Bicyclic Ring Substituted Heterobicyclic Protein Kinase Inhibitors - Compounds of the formula | 05-07-2009 |
| 20120197014 | SMALL MOLECULE INHIBITORS OF ISOPRENYLCYSTEINE CARBOXYL METHYLTRANSFERASE WITH POTENTIAL ANTICANCER ACTIVITY - The present invention generally relates to inhibitors of isoprenylcysteine carboxyl methyltransferase (Icmt), in particularly to compounds that inhibit Icmt activity and pharmaceutical compositions thereof. The invention also relates to methods of disease treatment using the same. | 08-02-2012 |
