Polycyclo ring system which contains the hetero ring as one of the cyclos

Subclass of:

540 - Organic compounds -- part of the class 532-570 series

540000000 - ORGANIC COMPOUNDS (CLASS 532, SUBCLASS 1)

540001000 - HETEROCYCLIC CARBON COMPOUNDS CONTAINING A HETERO RING HAVING CHALCOGEN (I.E., OXYGEN, SULFUR, SELENIUM OR TELLURIUM) OR NITROGEN AS THE ONLY RING HETERO ATOMS

540450000 - The hetero ring contains at least eight members including nitrogen and carbon

540451000 - Chalcogen double bonded directly to a ring carbon of the hetero ring which is adjacent to the ring nitrogen (e.g., laurolactam, etc.)

Patent class list (only not empty are listed)

Deeper subclasses:

Class / Patent application number	Description	Number of patent applications / Date published
540461000	Polycyclo ring system which contains the hetero ring as one of the cyclos	8
20090062528	Ansamycin formulations and methods of use thereof - Provided herein, inter alia, are solid forms of geldanamycin analogs, pharmaceutical compositions comprising a geldanamycin analog and a crystallization inhibitor, methods of making and using such compositions. Additionally, provided are methods for the treatment of cancer, a neoplastic disease state and/or a hyperproliferative disorder, and methods of inhibiting Heat Shock Protein 90 (“Hsp90”).	03-05-2009
20110034686	Process for Isolation and Purification of Geldanamycin - The present invention is successful in providing a suitable process for the isolation and purification of geldanamycin. The process provided in the instant invention is easy to scale-up, industrially safe and will give high yield and productivity.	02-10-2011
20130053553	HETEROCYCLIC COMPOUNDS - Described herein are methods for synthesizing heterocyclic, 8-membered ring structures. The methods may allow for preparation of highly substituted 8-membered rings. Also disclosed are heterocyclic, 8-membered ring compounds and pharmaceutical compositions comprising the compounds.	02-28-2013
20140235852	PROCESS FOR PREPARING AN INTERMEDIATE OF THE MACROCYCLIC PROTEASE INHIBITOR TMC 435 - The present invention relates to an improved process for preparing (2R,3aR,10Z,11aS,2aR,14aR)-cyclopenta[c]cyc-lopropa[g][1,6]diazacyclotetradecine-12a(1H)-carboxylic acid, 2,3,3a,4,5,6,7,8,9,11a,12,13,14,14a-tetradecahydro-2[[7-methoxy-8-methyl-2-[4-10 (1-methylethyl)-2-thiazolyl]-4-quinolinyl]oxy]-5-methyl-4,14-dioxo-, ethyl ester. This compound is an intermediate in the overall synthesis route of the macrocyclic compound TMC 435. TMC 435 is an inhibitor of NS3/4A protease which plays an important role in the replication of the hepatitis C virus.	08-21-2014
20140343277	NITROGEN-CONTAINING COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF ATRIAL FIBRILLATION - The present invention provides a novel diazepine compound that blocks the I	11-20-2014
540462000	Oxirane ring is one of the cyclos in the polycyclo ring system (e.g., maytansinol, etc.)	3
20130331564	EPOTHILONE DERIVATIVES - The present invention relates to compounds of the formula	12-12-2013
20140142297	METHODS FOR THE ACYLATION OF MAYTANSINOL - Disclosed is a method of preparing an amino acid ester of maytansinol by reacting maytansinol with an N-carboxyanhydride of an amino acid (NCA) in the presence of a drying agent. Also disclosed is an improved method of preparing an amino acid ester of maytansinol in which a nucleophile is added to the reaction mixture after completion of the reaction between maytansinol and an N-carboxyanhydride of an amino acid.	05-22-2014
20140179917	PREPARATION OF MAYTANSINOID ESTERS - Provided are efficient methods for direct coupling of a maytansinoid with a carboxylic acid to prepare a maytansinoid C-3 ester in high yield using a rare earth metal-based or trifluoromethanesulfonate-based Lewis acid catalyst and a base together with a coupling reagent. Also provided are compositions used in such methods.	06-26-2014