| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 534727000 | Phosphorus attached indirectly to an azo group by nonionic bonding | 7 |
| 20100087634 | Fluorous Oligonucleotide Reagents and Affinity Purification of Oligonucleotides - Fluorous-tagged oligonucleotide reagents and an oligonucleotide purification methodology making use thereof, the method comprising: Synthesizing oligonucleotides using oligonucleotide reagents each bearing at least one fluorous group to yield a mixture of synthesis products and reagents, the mixture including at least one target synthesized oligonucleotide bearing at least one fluorous group; passing the mixture through a separation medium having an affinity for the at least one fluorous group so that the target synthesized oligonucleotide bearing at least one fluorous group is adsorbed by the separation medium; washing the separation medium with at least a first solvent to selectively dissociate therefrom substantially all synthesis products and reagents of the heterogenous mixture other than the at least one target synthesized oligonucleotide bearing at least one fluorous group; and subsequently dissociating the at least one synthesized oligonucleotide from the separation medium, with or without the fluorous group. | 04-08-2010 |
| 20110092683 | PHOSPHONIUM SALTS DERIVATIVES AND USES THEREOF - There are provided compounds of formulas (VA), (VIA), (VIIA) (IXA), (XIA), (XIIA), (XIIIA), and (XIVA): | 04-21-2011 |
| 20110178280 | DARK QUENCHERS FOR DONOR-ACCEPTOR ENERGY TRANSFER - The present invention provides a family of dark quenchers, termed Black Hole Quenchers (“BHQs”), that are efficient quenchers of excited state energy but which are themselves substantially non-fluorescent. Also provided are methods of using the BHQs, probes incorporating the BHQs and methods of using the probes. | 07-21-2011 |
| 20110282041 | STABILIZED NUCLEIC ACID DARK QUENCHER-FLUOROPHORE PROBES - The present invention provides a new class of solids supports for synthesis of modified oligomers of nucleic acids, and nucleic acid probes that have a format expediently synthesized on the new supports. Exemplary solid supports include at least one quencher bound through a linker to the solid support. Various exemplary embodiments include a moiety that stabilizes a duplex, triplex or higher order aggregation (e.g., hybridization) of nucleic acids of which the oligomer of the invention is a component. Other components of the solid support include moieties that stabilize aggregations of nucleic acids, e.g., intercalators, minor groove binding moieties, bases modified with a stabilizing moiety (e.g., alkynyl moieties, and fluoroalkyl moieties), and conformational stabilizing moieties, such as those described in commonly owned U.S. Patent Application Publication No. 2007/0059752. | 11-17-2011 |
| 20120108799 | Modifications for Antisense Compounds - The invention pertains to modifications for antisense oligonucleotides, wherein the modifications are used to improve stability and provide protection from nuclease degradation. The modifications could also be incorporated into double-stranded nucleic acids, such as synthetic siRNAs and miRNAs. | 05-03-2012 |
| 20130225797 | OLIGONUCLEOTIDE AND USE THEREOF - Provided is an oligonucleotide containing an azobenzene derivative, represented by Formula (1) or (2) below: | 08-29-2013 |
| 20150126717 | Bis-Azo Colorants for Use as Bluing Agents - This invention relates to bis-azo colorants for use as bluing agents, laundry care compositions comprising bis-azo colorants that may serve as bluing agents, processes for making such bluing agents and laundry care compositions and methods of using the same. The bluing agents are generally comprised of at least two components: at least one chromophore component and at least one polymeric component. These bluing agents are advantageous in providing a whitening effect to fabrics, while not building up over time and causing undesirable blue discoloration to the treated fabrics. | 05-07-2015 |
