| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 534010000 | Radioactive metal containing (At. No. 43, 61 or 84+; or radioactive isotope of another metal) | 37 |
| 20080281086 | Methods, processes and materials for dispensing and recovering supported fluorous reaction components - A fluorous delivery or recovery material comprising a fluorous support material having a coating thereon, the coating comprising an amount of a fluorous reaction component that may be dispensed using non-gravimetric methods is disclosed. Also disclosed are methods for dispensing a fluorous reaction component comprising dispensing by non-gravimetric methods a predetermined amount of the fluorous reaction component as a coating on a fluorous support material. | 11-13-2008 |
| 20090005545 | METHODS FOR PURIFYING RADIOLABELLED COMPOUNDS - One aspect of the present invention relates to a method of purifying radiolabelled compounds comprising a) loading onto a fluorous polymer a radiolabelled compound precursor comprising a fluoroalkyl tin moiety; b) reacting the radiolabelled compound precursor with a radiolabel delivering compound to give a radiolabelled compound, wherein the fluoroalkyl tin moiety is replaced by a radiolabel; and c) eluting the radiolabelled compound from the fluorous polymer. | 01-01-2009 |
| 20100113756 | LUMINESCENT METAL COMPLEXES FOR MONITORING RENAL FUNCTION - Some embodiments of the present invention may be said to be directed to metal complexes of Formula I wherein at least one of X | 05-06-2010 |
| 20100160614 | Method and apparatus for isolating a radioisotope - A method of isolating a radioisotope according to example embodiments may include vaporizing a source compound containing a first isotope and a second isotope of an element, wherein the second isotope may have at least one of therapeutic and diagnostic properties when used as a radiopharmaceutical. The vaporized source compound may be ionized to form charged particles of the first and second isotopes. The charged particles may be separated to isolate the particles of the second isotope. The isolated charged particles of the second isotope may be collected with an oppositely-charged collector. Accordingly, the isolated second isotope may be used to produce therapeutic and/or diagnostic radiopharmaceuticals having higher specific activity. | 06-24-2010 |
| 20110009605 | NOVEL CONTRAST AGENTS - This invention includes agents and compositions having MRI, PET, CT, X-ray, SPECT or optical signals, and methods for their use in the determination of a target. In some cases, a MRI, PET, CT, X-ray, SPECT, optical or other signal produced by the agent or composition can be affected by the presence of the target. Examples of targets that can be determined by this invention include, but are not limited to zinc, copper, iron ions and other biological targets. Example of application for imaging in vivo includes the function of pancreas and other organs. | 01-13-2011 |
| 20120035351 | Volatile Imidazoles and Group 2 Imidazole Based Metal Precursors - Sterically hindered imidazole ligands are described, along with their synthesis, which are capable of coordinating to Group 2 metals, such as: calcium, magnesium, strontium, in an eta-5 coordination mode which permits the formation of monomeric or dimeric volatile complexes. | 02-09-2012 |
| 20120184722 | CHROMATOGRAPHY COMPONENTS - Disposable components for a separation and purification system include a flow cell, an end cap for a chromatography column, and a chromatography column useful for medium-pressure liquid chromatography (MPLC). | 07-19-2012 |
| 20140081009 | NOVEL CONTRAST AGENTS - This invention includes agents and compositions having MRI, PET, CT, X-ray, SPECT or optical signals, and methods for their use in the determination of a target. In some cases, a MRI, PET, CT, X-ray, SPECT, optical or other signal produced by the agent or composition can be affected by the presence of the target. Examples of targets that can be determined by this invention include, but are not limited to zinc, copper, iron ions and other biological targets. Example of application for imaging in vivo includes the function of pancreas and other organs. | 03-20-2014 |
| 20140163211 | 68Ga Generator - The present invention relates to a | 06-12-2014 |
| 20140343260 | PET/SPECT AGENTS FOR APPLICATIONS IN BIOMEDICAL IMAGING - Tracers that can be used for PET or SPECT imaging of the distribution of Pgp are disclosed. The tracers are metalloprobes that can comprise a radioactive metal ion such as | 11-20-2014 |
| 20150133645 | Labeled Alginate Conjugates For Molecular Imaging Applications - Described are bifunctional NOTA-based derivatives capable of conjugating with alginate and with metal ions, as well as NOTA-alginate conjugates which can be labeled with stable or radioactive metal ions. Also described are conjugation methods of the bifunctional NOTA-based linker with alginate, and methods of using radiometal-labeled NOTA-alginate conjugates or other radio-labeled alginate conjugates as imaging reagents. | 05-14-2015 |
| 20150374859 | Imaging compounds for tracking histone deacetylase inhibitor and synthesis method thereof - A synthesis method of labeling histone deacetylase inhibitor (HDAC inhibitors) SC027 with Gallium-67 or Gallium-68 radionuclide, wherein a labeled precursor DOTA-SC027 which comprises DOTA-NHS-ester (1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid-N-hydroxysuccinimide-ester) and HDACi-SC027 is prepared for the synthesis to label HDACi-SC027 with Gallium-67 or Gallium-68 radionuclide for producing imaging tracers for tracking the HDACi. | 12-31-2015 |
| 20160009664 | METAL COMPLEXES OF POLY(CARBOXYL)AMINE-CONTAINING LIGANDS HAVING AN AFFINITY FOR CARBONIC ANHYDRASE IX | 01-14-2016 |
| 20160083408 | ARSENIC COMPLEXES FOR POTENTIAL DIAGNOSTIC APPLICATIONS - The present invention provides radioactive arsenic complexes useful in diagnostic and therapeutic applications and methods for forming those arsenic complexes. | 03-24-2016 |
| 20160136309 | BIFUNCTIONAL CHELATING AGENTS BASED ON THE 1,4-DIAZEPINE SCAFFOLD (DAZA) FOR NON-INVASIVE MOLECULAR IMAGING - A compound fur radio metal complexation includes a chelator and one or more biological targeting vectors TV conjugated to said chelator, wherein the chelator has structure (A) or (B)or (C). | 05-19-2016 |
| 20160251378 | Transmetalation Methods for the Synthesis of PET and SPECT Imaging Agents | 09-01-2016 |
| 534011000 | Actinide series metal (At. No. 89+) | 5 |
| 20090286968 | 2-Quinoxalinol Salen Compounds and Uses Thereof - Disclosed are 2-quinoxalinol salen compounds and in particular 2-quinoxalinol salen Schiff-base ligands. The disclosed 2-quinoxalinol salen compounds may be utilized as ligands for forming complexes with cations, and further, the formed complexes may be utilized as catalysts for oxidation reactions. The disclosed 2-quinoxalinol salen compounds also may be conjugated to solid supports and utilized in methods for selective solid-phase extraction or detection of cations. | 11-19-2009 |
| 20120184723 | PREPARATION OF URANIUM COMPOUNDS | 07-19-2012 |
| 534012000 | Containing -C(=X)-, wherein X is chalcogen (e.g., carbonyl containing, etc.) | 3 |
| 20110282039 | METHOD OF SYNTHESIS OF ANHYDROUS THORIUM(IV) COMPLEXES - Method of producing anhydrous thorium(IV) tetrahalide complexes, utilizing Th(NO | 11-17-2011 |
| 534013000 | The -C(=X)- is part of a -C(=X)X- group, wherein the X's are the same or diverse chalcogens | 2 |
| 20110263837 | METHOD FOR PREPARING AN ACTINIDE(S) OXALATE AND FOR PREPARING AN ACTINIDE(S) COMPOUND - A method for preparing an oxalate of one or more actinides for processing and recycling nuclear fuel, comprising: the precipitation of said actinide or the coprecipitation of said actinides in the form of oxalate particles by bringing into contact an aqueous solution containing the actinide(s) with an aqueous solution of oxalic acid or of an oxalic acid salt; and the collection of the resulting oxalate particles; characterized in that the precipitation or coprecipitation is carried out in fluidized bed. | 10-27-2011 |
| 20140039169 | LUMINESCENT 1-HYDROXY-2-PYRIDINONE CHELATES OF LANTHANIDES - The present invention provides luminescent complexes between a lanthanide ion and an organic ligand which contains 1,2-hydroxypyridinone units. The complexes of the invention are stable in aqueous solutions and are useful as molecular probes, for example in medical diagnostics and bioanalytical assay systems. The invention also provides methods of using the complexes of the invention. | 02-06-2014 |
| 534014000 | Technetium containing (At. No. 43; Tc) | 16 |
| 20080214797 | Preparation method of radioisotope labeling compound using carbon nanotube - Disclosed herein is a method for the preparation of radioisotope-labeled compounds using CNT. It comprises filling the carbon nanotube with a radioisotope; and labeling a physiologically active material with the radioisotope charged in the carbon nanotube. Taking advantage of CNT, the method can prepare a radioisotope-labeled compound invention at a high yield and in a simple manner. Also, the radioisotope, when remaining unreacted, can be recovered by the filtration of the CNT, thereby achieving the prevention of radioactive contamination and the reduction of radioactive waste. Further, the radioisotope-labeled compound is useful as a contrast medium for imaging the hepatobiliary system. | 09-04-2008 |
| 20080227961 | BRIDGED AROMATIC SUBSTITUTED AMINE LIGANDS WITH DONOR ATOMS - The present invention provides for substituted metal chelating compounds in which at least two of the chelating atoms are nitrogen which are directly attached to aromatic rings and one or more of those nitrogen atoms has attached thereto a substituent other than hydrogen, and methods for making and using these compounds. | 09-18-2008 |
| 20090209740 | COMPOSITION FOR PREPARATION OF RADIOACTIVE PHARMACEUTICAL FOR DIAGNOSIS OF REGIONAL CEREBRAL BLOOD FLOW - An object of the present invention is to provide a composition for effectively labeling ECD with 99mTc within a short period of time. | 08-20-2009 |
| 20090240041 | TUMOR IMAGING COMPOUNDS - The invention provides novel amino acid compounds of use in detecting and evaluating brain and body tumors. These compounds combine the advantageous properties of α-aminoisobutyric acid (AIB) analogs namely, their rapid uptake and prolonged retention in tumors with the properties of halogen substituents, including certain useful halogen isotopes such as fluorine-18, iodine-123, iodine-124, iodine-125, iodine-131, bromine-75, bromine-76, bromine-77, bromine-82, astatine-210, astatine-211, and other astatine isotopes. In addition the compounds can be labeled with technetium and rhenium isotopes using known chelation complexes. The amino acid compounds disclosed herein have a high specificity for target sites when administered to a subject in vivo. The labeled amino acid compounds are useful as imaging agents in detecting and/or monitoring tumors in a subject by Positron Emission Tomography (PET) and Single Photon Emission Computer Tomography (SPECT). | 09-24-2009 |
| 20100160615 | INTERMEDIATE COMPOUND OF TECHNETIUM NITRIDE COMPLEX FOR RADIODIAGNOSTIC IMAGING - A bisphosphonoaminc compound represented by the following formula (I): wherein R1, R2, R3, R4 and R5 are independently an alkyl group having 1 to 6 carbon atoms, and n is an integer of 1 to 6, is extremely useful as an intermediate for preparing a technetium nitride complex for radiodiagnostic imaging. | 06-24-2010 |
| 20100228012 | PENDANT FATTY ACID IMAGING AGENTS - The disclosure provides pendant fatty acid compounds for use in diagnostic imaging, (particularly the cardiovascular system), as well as kits comprised of the same. The disclosure also provides for a method administering a imaging agent with a high specificity for the myocardium. | 09-09-2010 |
| 20110065904 | H3LMN COMPOUND USED AS RADIOACTIVE AGENT FOR TREATMENT OF LIVER CANCER AND MANUFACTURING METHOD THEREOF | 03-17-2011 |
| 20120077967 | NOVEL TECHNETIUM AND RHENIUM COMPLEXES - Novel radioactive technetium and rhenium complexes comprising tripodal ligands are provided by the present invention. In particular, Tc(I) complexes are provided by the present invention. Novel ligands suitable for the formation of the technetium and rhenium complexes of the invention are also provided, as well as radiopharmaceutical compositions comprising said complexes, kits for their preparation. The invention also relates to the use of | 03-29-2012 |
| 20120208988 | HETERODIMERS OF GLUTAMIC ACID - Compounds of Formula (Ia) | 08-16-2012 |
| 20130131327 | Tricarbonyl Complexes with Tridentate Chelators for Myocardium Imaging - Chelators of the formulae (I), (II) and (III) | 05-23-2013 |
| 20140031533 | PRECURSOR USED FOR LABELING HEPATORCYTE RECEPTOR AND CONTAINING TRISACCHARIDE AND DIAMIDE DEMERCAPTIDE LIGAND, METHOD FOR PREPARING THE SAME, RADIOTRACER AND PHARMACEUTICAL COMPOSITION OF THE SAME - A precursor used for labeling hepatocyte receptors and applied to radiotracers for imaging or pharmaceutical compositions for liver cancers is revealed. The precursor is a bifunctional compound. The bifunctional group includes a trisaccharide structure and a diamide dimercaptide (N | 01-30-2014 |
| 20140058071 | FIBROSIS SPECIFIC MULTIMERIC PEPTIDOMIMETIC RADIOTRACERS - The present invention describes peptidomimetic radiotracers. In particular, the present invention discloses fibrosis specific multimeric small-molecule peptidomimetic radiotracers. | 02-27-2014 |
| 20140121361 | NOVEL N3S1 CHELATOR-FOLATE DERIVATIVES, PREPARATION METHOD THEREOF AND COMPOSITION FOR DIAGNOSIS OR TREATMENT OF CANCER CONTAINING THE SAME AS AN ACTIVE INGREDIENT | 05-01-2014 |
| 20140336368 | MULTIMODAL CONTRAST AND RADIOPHARMACEUTICAL AGENT FOR AN IMAGING AND A TARGETED THERAPY GUIDED BY IMAGING - A multimodal contrast and radiopharmaceutical agent for an imaging and a targeted therapy guided by imaging. | 11-13-2014 |
| 20140371434 | RADIOTRACER PRECURSOR FOR IMAGING OF HYPOXIC TISSUE, RADIOTRACER, AND METHOD FOR PREPARING THE SAME - A radiotracer precursor for imaging of hypoxic tissues, a radiotracer and a method for preparing the same are revealed. The radiotracer precursor, DANI, includes a nitroimidazole functional group with a feature of retention in hypoxic tissues and a bifunctional ligand able to complex with radioisotopes. Thus DANI can be used to produce radiotracers stayed in hypoxic tissues and the radiotracers are applied to medical imaging of malignant tumor with hypoxic layer. | 12-18-2014 |
| 20150322005 | PRECURSOR FOR LABELING THERAPEUTIC AGENT FOR LIVER CANCER AND METHOD FOR MANUFACTURING THE SAME - A precursor for labeling therapeutic agents for liver cancer and a method for manufacturing the same are revealed. The chemical structure of the precursor has a ligand linked to complex compounds of radioisotopes. Moreover, the chemical structure of the precursor further includes a specific functional group soluble in Lipiodol or having properties of Lipiodol. Thus the radioisotopes attached to the precursor are allowed to retain in hepatic tissues of patients with liver cancer for internal radiation therapy of liver cancer. | 11-12-2015 |
