Class / Patent application number | Description | Number of patent applications / Date published |
530367000 | Ovalalbumin, e.g., avidin, conalbumins, etc. | 13 |
20120071633 | METHOD FOR PURIFICATION OF TARGET POLYPEPTIDES - The present invention relates to a process for purification of a target molecule, comprising the steps: (a) contacting a target molecule, and a population of target binding polypeptides (TBP), in solution for a sufficient time to allow complex formation; and (b) isolating the target from the complex from (a) by subsequent purification steps, wherein (i) the target binding polypeptides have at least two binding functionalities; a first binding functionality towards the target and a second binding functionality towards a catching ligand comprised in a solid support; and (ii) the first binding functionality comprises at least two binding sites for the target, and the target comprises at least two binding sites for the TBP. | 03-22-2012 |
20120202972 | Motor proteins propelling nano-scale devices and systems - An embodiment can be the use of motor proteins for cargo loading and transport in nano-devices and systems. One embodiment of the use of motor proteins can be adding biotin-binding proteins to a substrate by patterning, binding biotinylated F-actin to the biotin-binding proteins, aligning the bound F-actin in a preferred direction using a flow field, and using myosin coated particles to transport items attached to the particle throughout the substrate. Another embodiment of the use of motor proteins can be adding biotin-binding proteins to a substrate by patterning, adding a flow field, injecting F-actin so that the F-actin is bound and aligned simultaneously, and using myosin coated particles to transport items attached to the particle throughout the substrate. In either embodiment the F-actin can be capped with a biotinylated cap before binding to the biotin-binding proteins. | 08-09-2012 |
20120214970 | High Stability Streptavidin Mutant Proteins - The present invention provides a mutant streptavidin subunit which comprises one or more amino acid substitutions compared to a wildtype streptavidin subunit at any one of residue positions equivalent to positions (50, 51, 52, 53) and (54) of SEQ ID NO. 2 and wherein amino acid residues at positions equivalent to positions (23, 27, 43, 45, 49, 79, 88, 90, 92, 108, 110) and (128) of SEQ ID NO. 2, in said mutant streptavidin subunit, are wildtype, wherein (i) when said mutant streptavidin subunit unit is comprised in streptavidin, said streptavidin has a lower off rate for biotin or for a biotin conjugate than wildtype streptavidin or (ii) when said mutant streptavidin subunit is in monomelic form said mutant monomelic streptavidin has a lower off rate for biotin or a biotin conjugate than monomelic streptavidin. The invention also encompasses nucleic acid molecules comprising a nucleotide sequence encoding the mutant streptavidin subunit and vectors and cells comprising the nucleic acid. Further, methods of capturing biotinylated molecules and cells and therapeutic methods are encompassed. | 08-23-2012 |
20130079497 | PYRENYLOXYSULFONIC ACID FLUORESCENT AGENTS - The invention provides a novel class of reactive fluorescent agents that are based on a pyrene sulfonic acid nucleus. The agents are readily incorporated into conjugates with other species by reacting the reactive group with a group of complementary reactivity on the other species of the conjugate. Also provided are methods of using the compounds of the invention to detect and/or quantify an analyte in a sample. In an exemplary embodiment, the invention provides multi-color assays incorporating the compounds of the invention. | 03-28-2013 |
20140163206 | HAPTENS OF ARIPIPRAZOLE - The invention relates to compounds of Formula I, wherein R | 06-12-2014 |
20140213766 | HAPTENS OF OLANZIPINE - The invention relates to compounds of Formula I, wherein R | 07-31-2014 |
20140213767 | HAPTENS OF PALIPERIDONE - The invention relates to compounds of Formula I, wherein L | 07-31-2014 |
20140221616 | HAPTENS OF QUETIAPINE - The invention relates to compounds of Formula I, wherein R | 08-07-2014 |
20150065688 | SURFACES HAVING NANOPARTICULATE LAYERS AND ASSEMBLY AND USE THEREOF - A method for generating layered structures is disclosed. The method comprises reacting an azide-functionalized material with an alkyne-functionalized material, one of which can be a nanoparticle or a microparticle and the other can be a substrate or another nanoparticle or microparticle. The method also includes generating layered structures having multiple layers which can be built up in multiple azide-alkyne reaction steps. | 03-05-2015 |
20160002316 | SERPINS: METHODS OF THERAPEUTIC BETA-CELL REGENERATION AND FUNCTION - Compositions and methods of use are provided for improving β cell function and promoting pancreatic β cell proliferation in vitro, in vivo and ex vivo. The active agents of the pending invention comprise Serpin family peptides (e.g., SerpinB1), functional and structural analogs of Serpin family peptides and nucleic acids encoding Serpin family peptides, as well as active fragments thereof. | 01-07-2016 |
530368000 | Separation, purification or synthesis | 3 |
20120130050 | BIOMOLECULE FIXING BOARD AND METHOD OF MANUFACTURING THE SAME - This invention provides a biomolecule modifying substrate comprising biomolecules selectively fixed to given regions thereon. The biomolecule modifying substrate comprises: a substrate at least comprising a first surface and a second surface; a first linker molecule comprising a hydrocarbon chain and a functional group capable of selectively binding to the first surface at one end of the hydrocarbon chain, which is bound to the first surface via such functional group; a second linker molecule comprising a reactive group capable of binding to the hydrocarbon chain of the first linker molecule, which is bound to the first linker molecule via a bond between the reactive group and the hydrocarbon chain; and a biomolecule bound thereto via the second linker molecule. | 05-24-2012 |
20140066596 | ISOLATED EGG PROTEIN AND EGG LIPID MATERIALS, AND METHODS FOR PRODUCING THE SAME - A method for separating proteins and fats from an egg mixture is disclosed herein. The method includes a step of microfiltration of the egg mixture, wherein microfiltration includes pumping across a filter an egg mixture containing egg yolk and egg whites (albumen). An egg powder obtained from egg and a high gel strength egg powder are also disclosed. | 03-06-2014 |
20150094453 | ISOLATED EGG PROTEIN AND EGG LIPID MATERIALS, AND METHODS FOR PRODUCING THE SAME - A method for separating proteins and fats from an egg mixture is disclosed herein. The method includes a step of microfiltration of the egg mixture, wherein microfiltration includes pumping across a filter an egg mixture containing egg yolk and egg whites (albumen). An egg powder obtained from egg and a high gel strength egg powder are also disclosed. | 04-02-2015 |