| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 530325000 | 24 amino acid residues in defined sequence | 7 |
| 20080242836 | Convergent Solid Phase Peptide Synthesis By Reaction Of Two Fragments Bound To Solid Support - A process for preparing a peptide or protein by solid phase synthesis comprising combining a sequence including one or more amino acids obtainable by C-N synthesis linked to a first resin, with an amino acid sequence including one or more amino acid obtainable by N-C synthesis linked to a second resin so as to create a native peptide link between unprotected N and unprotected C terminals of said amino acid sequences, and optionally releasing the resulting peptide from one or more of the linked resins so as to combine with further N-C or C-N sequences or to release the desired peptide or protein sequence. | 10-02-2008 |
| 20090137779 | Peptide inhibitors of thrombin as potent anticoagulants - The tetrapeptide Phe-Asn-Pro-Arg (SEQ ID NO: 3) is a structurally-optimized sequence for binding to the active site of thrombin. By conjugating this tetrapeptide or variants thereof to a C-terminal fragment of hirudin, we were able to generate a series of new multivalent inhibitors of thrombin containing only genetically encodable natural amino acids. We found that synergistic binding to both the active site and an exosite of thrombin can be enhanced through substitutions of amino acid residues at the P | 05-28-2009 |
| 20100145012 | ANTI-CANCER BIOACTIVE PEPTIDE - An anti-cancer bioactive peptide having an amino acid sequence as shown in SEQ ID NO.1, or a functional analogue thereof prepared by substitution, insertion, or deletion of one or more amino acids of SEQ ID NO. 1, or a peptide having 90% homology in amino acid sequence with that of SEQ ID NO. 1. The anti-cancer bioactive peptide of the invention can selectively kill cancer cells and exhibit low cytotoxicity against normal cells. | 06-10-2010 |
| 20100152420 | PEPTIDE NETWORKS - Methods of modulating interfacial characteristics in a self-assembled, force-transmitting peptide network at a fluid-fluid interface are disclosed. The methods involve exposing a peptide capable of participating in a self-assembled, force-transmitting peptide network, either before or after it interacts with other peptides to form the peptide network to a stimulus that alters the chemical and/or physical properties of the peptide. Use of such methods in applications such as emulsions and foams are also disclosed. | 06-17-2010 |
| 20100267927 | Structure of the Insulin Receptor Ectodomain - The present invention relates to the crystal structure of the insulin receptor ectodomain, to the nature of its N-linked glycans and to methods of using the crystal and related structural information to screen for and design compounds that interact with or modulate the insulin receptor and/or the closely-related insulin-like growth factor receptors or variants thereof. | 10-21-2010 |
| 20100267928 | ACTIVATABLE DIAGNOSTIC AND THERAPEUTIC COMPOUND - The present invention relates to a compound which can be used as a contrast medium and as a therapeutic agent, the use of the compound for manufacturing a diagnostic or therapeutic composition, a diagnostic and therapeutic composition which comprises the compound, and a method for the diagnostic and therapeutic treatment of a living being. | 10-21-2010 |
| 20140249294 | PROCESS FOR PRODUCTION OF PEPTIDE THIOESTER - A process for chemically converting a peptide chain into a peptide thioester includes, when a —C(═X)—R | 09-04-2014 |
