| Entries |
| Document | Title | Date |
|---|
| 20080200612 | Anionic and Cationic Saccharide-Siloxane Copolymers - Ionically-modified saccharide siloxane copolymers that comprises a reaction product between an ionic monomer or oligomer and a saccharide-siloxane copolymer, wherein the saccharide-siloxane copolymer has a specified formula, are provided. Dispersions, including emulsions, comprising the ionic saccharide-siloxane copolymers, and methods for manufacturing these compositions, dispersions, and emulsions are also provided. | 08-21-2008 |
| 20080287604 | Hydrogel Including Modified Cyclodextrin Crosslinked With Polyurethane Prepolymer - A hydrogel composition comprising a modified cyclodextrin crosslinked with a polyurethane prepolymer. In one embodiment, the hydrogel includes a ratio of the modified cyclodextrin to the polyurethane prepolymer selected to result in formation of the hydrogel. The hydrogel composition may be used in a personal care product. A process for preparing a hydrogel, including providing a modified cyclodextrin; providing a polyurethane prepolymer; combining the modified cyclodextrin with the polyurethane prepolymer; and allowing the polyurethane prepolymer to react with and crosslink the cyclodextrin to form the hydrogel. A process for preparing a hydrogel-containing article such as a personal care product, including preparing the hydrogel and applying it or the components thereof to a suitable substrate. | 11-20-2008 |
| 20090062467 | Pressure-Sensitive Adhesive Composition and Pressure-Sensitive Adhesive Sheet Using the Same - A pressure-sensitive adhesive layer of pressure-sensitive adhesive sheet is formed by using: a pressure-sensitive adhesive composition comprising (A) a polyrotaxane having a linear-chain molecule passing through opening portions of at least two cyclic molecules, the cyclic molecules having a reactive group, the polyrotaxane having blocking groups at both ends of the linear-chain molecule, and (B) a pressure-sensitive adhesive polymer having two or more functional groups capable of reacting with the reactive group; or, a pressure-sensitive adhesive composition comprising (A) a polyrotaxane having a linear-chain molecule passing through opening portions of at least two cyclic molecules, the cyclic molecules having a reactive group, the polyrotaxane having blocking groups at both ends of the linear-chain molecule, (B′) a pressure-sensitive adhesive polymer having two or more reactive groups, and (C) a compound having two or more functional groups capable of reacting with the reactive group of the polyrotaxane (A) and the reactive groups of the polymer (B′). As a result there can be provided a pressure-sensitive adhesive sheet comprising a pressure-sensitive adhesive layer excellent in flexibility and having high gel fraction and durability, and a pressure-sensitive adhesive composition that constitutes the pressure-sensitive adhesive layer. | 03-05-2009 |
| 20090105415 | AMPHIPHILIC POLYMER AND METHOD FOR PREPARING THE SAME - An amphiphilic polymer having the following formula (I): | 04-23-2009 |
| 20090111939 | Method for Purifying a Contaminated Solvent and Concurrently Producing a Semi-Finished Product for Use in the Production of Panels - The invention relates to a method for purifying a contaminated solvent and concurrently producing a semi-finished product for use in the production of panels. The inventive method is characterized in that it comprises following steps: a) providing a first mass of fibrous material; b) softening at least part of a second mass of plastic material by impregnating it with a contaminated solvent adapted to at least partially dissolve said plastic material; c) mixing said fibrous material with the mass of softened plastic material to produce a compound; d) pressing said compound at a temperature that is at least equal to the melting temperature of said plastic material to obtain a semi-finished panel and a fraction of evaporated solvent. | 04-30-2009 |
| 20090131588 | MODIFIED HYDROPHILIC POLYROTAXANE AND CROSS-LINKED POLYROTAXANE - [Object] To provide a modified hydrophilic polyrotaxane which is soluble in water or a water-like solvent, a cross-linked polyrotaxane using this, and a solvent for dissolving the modified hydrophilic polyrotaxane.
| 05-21-2009 |
| 20090137738 | LADDER COPOLYMERS - The present invention relates to a copolymer termed a ladder copolymer because it has two backbones that serve as legs/sides of a ladder structure. These two backbones, one of which is a nucleic acid or nucleic acid-like polymer, are linked together as the legs/sides of a ladder are linked together by the rungs. | 05-28-2009 |
| 20090215958 | CONDUCTING POLYMERS AND USES THEREOF - A conducting polymer including a conducting linker to connect a probe to the polymer, the linker including an unsaturated organic chain. | 08-27-2009 |
| 20090215959 | FLUOROPLASTIC SILICONE VULCANIZATES - Fluoroplastics containing fluorocarbon resins and silicones are prepared by first mixing a fluorocarbon resin with a compatibilizer, then adding a curable organopolysiloxane with a radical initiator, and vulcanizing the organopolysiloxane in the mixture. The fluoroplastics can be processed by various techniques, such as extrusion, vacuum forming, injection molding, blow molding or compression molding, to fabricate plastic parts. The resulting fabricated parts can be re-processed (recycled) with little or no degradation of mechanical properties. | 08-27-2009 |
| 20090299007 | BIOLOGICALLY ABSORBABLE COATINGS FOR IMPLANTABLE DEVICES BASED ON POLYESTERS AND METHODS FOR FABRICATING THE SAME - Polymers containing polyesters and, optionally, agents for use with medical articles and methods of fabricating the same are disclosed. The medical article generally comprises an implantable substrate having a coating, and the coating contains a polymer comprising a polymeric product of a reaction comprising a polyol and a polycarboxylic acid. | 12-03-2009 |
| 20090306291 | SUGAR CHAIN-CAPTURING SUBSTANCE AND USE THEREOF - The present invention provides a method for preparing a sample characterized by binding a substance A containing a hydrazide group to a sugar chain and/or a sugar derivative via hydrazone formation between the hydrazide group of the substance A and the reducing end of the sugar chain and/or the sugar derivative thereby to enable the separation and purification of the sugar chain and/or the sugar derivative for an analytical sample from a biological sample containing the sugar chain and/or the sugar derivative by a simple operation. | 12-10-2009 |
| 20090312490 | Compound having crosslinked polyrotaxane and process for producing the same - It is intended to provide a crosslinked polyrotaxane formed by crosslinking polyrotaxane molecules via chemical bonds which exhibits excellent optical properties in water or in an aqueous solution of sodium chloride; a compound having this crosslinked polyrotaxane; and a process for producing the same. The above object can be achieved by a crosslinked polyrotaxane having at least two polyrotaxane molecules, wherein linear molecules are included in a skewered-like state at the opening of cyclodextrin molecules and blocking groups are provided at both ends of the linear molecules, so as to prevent the cyclodextrin molecules from leaving, and cyclodextrin molecules in at least two polyrotaxane molecules being bonded to each other via chemical bond, characterized in that hydroxyl (—OH) groups in the cyclodextrin molecules are partly substituted with non-ionic groups. | 12-17-2009 |
| 20090326150 | SYNTHESIS OF POLY-(P-ARYLENEETHYNYLENE)S IN NEAT WATER UNDER AEROBIC CONDIT - Provided are ethyne synthons comprising boron and related methods. Also provided are related water-soluble arylethynylene polymers capable of being synthesized in neat water under aerobic conditions. | 12-31-2009 |
| 20100010159 | Functionalized Inclusion Complexes As Crosslinkers - The present disclosure relates to crosslinked polymer compositions comprising an inclusion complex functionalized with one or more reactive groups and a polymer functionalized with one or more complimentary reactive groups. | 01-14-2010 |
| 20100029849 | HIGH MOLECULAR WEIGHT DERIVATIVE OF NUCLEIC ACID ANTIMETABOLITE - [Problems] A derivative of a nucleic acid antimetabolite is demanded which can show a higher therapeutic effect at a lower dose. | 02-04-2010 |
| 20100048815 | Electrically Conducting Polymers - The present invention provides a polymer for use in detecting or quantifying an analyte Exposure of the polymer to the analyte is capable of causing a shift in the onset potential for conductivity or semiconductivity of the polymer. A sensor for an analyte comprising the polymer is also described. | 02-25-2010 |
| 20100093935 | METHOD OF PREPARING POLYGLUTAMATE CONJUGATES - Methods for preparing and isolating polymer conjugates that include a recurring unit of Formulae (I) and (Ia) are described herein. The polymer conjugates can include an anti-cancer drug. | 04-15-2010 |
| 20100105835 | MOLDED ARTICLE HAVING HEAT RESISTANCE AND IMPACT RESISTANCE - The present invention provides a molded article of a resin containing poly-L-lactic acid, which is excellent in heat resistance and drop impact resistance. There is disclosed a molded article characterized in that said molded article is made from a resin composition obtained by compounding a functional filler into a resin made from a poly-L-lactic acid, the functional filler being yielded by a copolymerization of a compound having 2-4 hydroxyl groups with 1-100 molecules of D-lactic acid and a low-molecular-weight polymer selected from a group consisting of glycols, aliphatic polyesters and aromatic polyesters. The resin molded article according to the present invention exerts excellent drop impact resistance without sacrificing heat resistance. | 04-29-2010 |
| 20100113695 | HIGH CAPACITY NON-VIRAL VECTORS - Non-viral vectors for delivering agents to a site within the body of an animal comprise a biocompatible nanoparticle conjugated to an avidin/biotin complex and a water soluble linear polymer comprising multiple binding sites. The agents to be delivered are conjugated to each of the multiple binding sites, thereby increasing the loading capacity of the system. Where the agents comprise siRNA, each biotin/avidin complex may carry greater than four siRNA. The biocompatible nanoparticle may also comprise a fluorescent dye for in vivo imaging. | 05-06-2010 |
| 20100168331 | Thermoplastic Resin Composition - A thermoplastic resin composition of the present invention has high impact resistance, not lowering the weather resistance thereof, even though the amount of an impact resistance improver added thereto is small. The thermoplastic resin composition contains 100 parts by weight of (A) a thermoplastic resin and from 0.5 to 20 parts by weight of (B) a graft copolymer, wherein the graft copolymer (B) contains from 70% to 99% by weight of a crosslinked core (b2) prepared through polymerization of a monomer for the core (b2), containing 70% by weight or more of an acrylate, in the presence of from 0.5% to 20% by weight of a non-crosslinked seed (b1) having a weight-average molecular weight of 40,000 or less, and from 0.5% to 10% by weight of a shell (b3) prepared through polymerization of a monomer for the shell (b3) containing 50% by weight or more of a methacrylate, and the thermoplastic composition further contains from 0.01 to 3.0 parts by weight of (C) a water-soluble polymer compound having the property of forming a physical gel, relative to 100 parts by weight of the graft copolymer (B). | 07-01-2010 |
| 20100179284 | POLYMERS WITH BIO-FUNCTIONAL SELF ASSEMBLING MONOLAYER ENDGROUPS FOR THERAPEUTIC APPLICATIONS AND BLOOD FILTRATION - Medical device, prosthesis, or packaging assembly made up of polymer body comprising at least one polymer having the formula R(LE)x wherein R is a polymeric core having a number average molecular weight of from 5000 to 7,000,000 daltons, and having x endgroups, x is an integer≧1, E is an endgroup which is covalently linked to polymeric core R by linkage L, L is a divalent oligomeric chain which has at least 5 repeat units and which can self-assembly with L chains on adjacent molecules of the polymer, and moieties L and/or E in the polymer(s) may be the same as or different from one another in composition and/or molecular weight. The polymer body includes plural polymer molecules located internally within the body, at least some of which internal polymer molecules have endgroups that form a surface of the body. The surface endgroups include at least one self-assembling moiety. | 07-15-2010 |
| 20100190928 | POLYMERIC CONJUGATES OF DOXORUBICIN WITH PH-REGULATED RELEASE OF THE DRUG AND A METHOD OF PREPARING - A polymeric drug in the form of a conjugate of a copolymer of N-(2-hydroxypropyl)-methacrylamide (HPMA) with doxorubicin bound to the polymer via spacers containing hydrolytically cleavable hydrazone bonds, of formula (I), wherein SP | 07-29-2010 |
| 20100234528 | SUPPORTS FOR OLIGOMER SYNTHESIS - Universal linkers, their facile processes of manufacture and methods of using the same are provided. | 09-16-2010 |
| 20100249321 | Polymerisation of ethylenically unsaturated monomers - Ethylenically unsaturated, particularly acrylic, monomers are polymerised using a catalyst system including a manganese carbonyl initiator, an organic halogen reactive substrate and an allylic halide chain termination agent. Desirably the manganese carbonyl initiator is a dimanganese compound, particularly dimanganese decacarbonyl (Mn | 09-30-2010 |
| 20110003936 | Soil hydrophilization agent and methods for use - Disclosed are soil additives capable of hydrophilizing soil particles and/or increase available water capacity in soil. The soil additive are capable of increasing the available water content/capacity (AWC) in soils, the additive in one embodiment comprising a polymer composition having a hydrophilic portion and a hydrophobic portion, wherein the hydrophobic portion of the copolymer binds with the soil particle surface and the hydrophilic portion of the copolymer can bind with water. This results in the prevention, arrest or decelerated loss of water from the targeted area, for example the plant root zone, which allows for improved water usage efficiency by plants, grasses, vegetation, etc. | 01-06-2011 |
| 20110003937 | POLYMER CAPABLE OF ADSORBING ACIDIC WATER-SOLUBLE TARGET SUBSTANCE, AND METHOD FOR PRODUCTION OF THE POLYMER - To provide a polymer which selectively adsorbs an acidic water-soluble target substance, a polymer which has a specific recognition site for an acidic water-soluble target substance, a production process thereof, and an acidic water-soluble target substance-adsorbing agent. | 01-06-2011 |
| 20110065863 | FUNCTIONALIZED POLYSILOXANES, METHOD OF PREPARING SAME AND USES THEREOF - Novel polysiloxanes grafted with at least one polyhydroxylated amino compound, method for preparing same and uses thereof. | 03-17-2011 |
| 20110190445 | INHIBITION OF HRP-3 USING MODIFIED OLIGONUCLEOTIDES - The present invention refers to agents for modulating the activity of proteins having a PWWP domain. | 08-04-2011 |
| 20120035322 | POLYNUCLEIC ACID-ATTACHED PARTICLES AND THEIR USE IN GENOMIC ANALYSIS - Disclosed are methods for preparing particle-linked polynucleotides, and using the particle linked polynucleotides in genomic analysis. The particles as disclosed are characterized as having a size variance of less than 2%. | 02-09-2012 |
| 20120101229 | MODIFIED POLYACRYLAMIDE HYDROGEL - The invention relates to a salt resistant water absorbing compound including a polymeric phase that includes polyacrylamide and at least one of di or poly saccharide, wherein the polyacrylamide is cross-linked in the presence of at least one of di or poly saccharide by a cross-linking agent including multivalent cations, complexes thereof, organic cross-linking agents, or any combination thereof. | 04-26-2012 |
| 20120123055 | Multifunctional Forms of Polyoxazoline Copolymers and Drug Compositions Comprising the Same - The present disclosure provides copolymers of 2-substituted-2-oxazolines possessing two or three reactive functional groups which are also chemically orthogonal. The copolymers described may be random copolymers, block copolymers or a mixture of random and block copolymer configurations. Furthermore, the present disclosure provides novel methods for synthesizing the above polymers and for conjugating to molecules such as targeting, diagnostic and therapeutic agents. | 05-17-2012 |
| 20120157626 | Hybrid Superparamagnetic Iron Oxide Nanoparticles And Polyethylenimine As A Magnetoplex For Gene Transfection - Disclosed are the nanoparticle and the method for the same, and the preparing method includes steps of mixing polyethylenimine (PEI) with the poly(acrylic acid)-bound iron oxide (PAAIO) to form a PEI-PAAIO polyelectrolyte complex (PEC) and mixing the PEI-PAAIO PEC with genetic material such as plasmid DNA to form the PEI-PAAIO/pDNA magnetic nanoparticle. The PEI-PAAIO/pDNA magnetoplex is highly water dispersible and suitable for long term storage, shows superparamagnetism, low cytotoxicity, high stability and nice transfection efficiency, and thus the PEI-PAAIO PEC can replace PEI as a non-viral gene vector. | 06-21-2012 |
| 20120172525 | COMPOSITIONS CONTAINING INCLUSION COMPLEXES - The invention provides a composition containing particulate composite of a polymer and a therapeutic agent. The composition also contains a complexing agent. The polymer interacts with the complexing agent in a host-guest or a guest-host interaction to form an inclusion complex. A therapeutic composition of the invention may be used to deliver the therapeutic agent and to treat various disorders. Both the polymer of the particulate composite and the complexing agent may be used to introduce functionality into the therapeutic composition. The invention also relates to a method of preparing a composition. The method combines a therapeutic agent, a polymer having host or guest functionality, and a complexing agent having guest or host functionality to form the therapeutic composition. The complexing agent forms an inclusion complex with the polymer. The invention also relates to a method of delivering a therapeutic agent. According to the method, a therapeutically effective amount of a therapeutic composition of the invention is administered to a mammal (e.g. person or animal) in recognized need of the therapeutic. Also disclosed are compounds having the formula: | 07-05-2012 |
| 20120190793 | METHOD FOR THE PRODUCTION OF SCAFFOLDS FOR TISSUE ENGINEERING, COMPRISING THE USEOF AN ANCHORING UNIT, AND SCAFFOLD PRODUCED THEREWITH - The present invention relates to a method for the production of scaffold materials and/or scaffolds for tissue and/or organ engineering, said method comprising the addition of at least one anchoring unit for a labelling agent, to at least one scaffold material and/or to at least one scaffold. | 07-26-2012 |
| 20120322944 | WATER SOLUBLE NEAR INFRARED SENSING POLYMERS WITH LOW BAND GAPS - The present invention is directed to polymeric materials including a copolymer of at least a first and second monomer that have desirable electrical and optical properties, such as a low band gap and near infrared (NIR) absorption, respectively. More specifically, the present invention is directed to polymeric materials with charge neutrality that display increased solubility in aqueous media while retaining their electrical and optical properties. The polymeric materials in accordance with the present invention can be modified with any desired functional group to tailor the polymer materials for a specific application. Also described are methods of making the polymeric materials in accordance with the present invention. | 12-20-2012 |
| 20130012658 | POLYMER PARTICLES, NUCLEIC ACID POLYMER PARTICLES AND METHODS OF MAKING AND USING THE SAME - The disclosure relates to methods of making polymer particles, said methods including the steps of: making an aqueous gel reaction mixture; forming an emulsion having dispersed aqueous phase micelles of gel reaction mixture in a continuous phase; adding an initiator oil comprising at least one polymerization initiator to the continuous phase; and performing a polymerization reaction in the micelles. Further, the initiator oil is present in a volume % relative to a volume of the aqueous gel reaction mixture of between about 1 vol % to about 20 vol %. The disclosure also relates to methods of making nucleic acid polymer particles having the same method steps and wherein the aqueous gel reaction mixture includes a nucleic acid fragment, such as a primer. | 01-10-2013 |
| 20130109808 | GLUCOSAMINE MATERIALS | 05-02-2013 |
| 20130197160 | COPOLYMER SYNTHESIZED FROM A MODIFIED GLYCOSAMINOGLYCAN (GAG) AND AN ANHYDRIDE FUNCTIONALIZED HYDROPHOBIC POLYMER - A new copolymer synthesized from a glycosaminoglycan (GAG) such as hyaluronan/hyaluronic acid (HA), chondroitin sulfates, derma tan sulfates, keratan sulfates, heparan sulfate, and heparin, and an anhydride functionalized hydrophobic polymer, i.e., any polyolefin which has been ‘functionalized’ (grafted onto the backbone or incorporated into the backbone) with anhydride functional groups, such as maleic anhydride-graft-polyethylene, (or, maleated polyethylene), maleic anhydride-graft-polystyrene, maleic anhydride-graft-polypropylene, etc. The functionalized polyolefin may be a polyolefin backbone to which the anhydride functional groups have been grafted, or otherwise incorporated with the backbone. Also, a unique synthesis technique combines a modified GAG with a graft polyolefin, resulting in a unique copolymer with its constituents by-and-large covalently bound to each other. | 08-01-2013 |
| 20130211006 | Conjugated Polymeric Particle and Method of Making Same - A method of conjugating a substrate includes exchanging a counter ion associated with a biomolecule with a lipophilic counter ion to form a biomolecule complex, dispersing the biomolecule complex in a nonaqueous solvent, and coupling the biomolecule complex to a substrate in the presence of the nonaqueous solvent. | 08-15-2013 |
| 20130253135 | POLY(AMIDE) POLYMERS FOR THE DELIVERY OF OLIGONUCLEOTIDES - The present invention provides poly(amide) polymers, polyconjugates, compositions and methods for the delivery of oligonucleotides for therapeutic purposes. | 09-26-2013 |
| 20130289207 | MEMBRANE LYTIC POLY(AMIDO AMINE) POLYMERS FOR THE DELIVERY OF OLIGONUCLEOTIDES - The present invention provides membrane lytic poly(amido amine) polymers, polyconjugates, compositions and methods for the delivery of oligonucleotides for therapeutic purposes. | 10-31-2013 |
| 20130303695 | HYALURONIC ACID-CONTAINING BIOPOLYMERS - Novel hyaluronic acid-containing biopolymers are provided which exhibit increased hydrophilicity and reduced protein adsorption. In one aspect, the biopolymer incorporates hyaluronic acid modified to include a linking agent in a molar excess sufficient to yield a degree of HA modification in a range of about 1-5. In another aspect, the biopolymer incorporates unmodified hyaluronic acid. | 11-14-2013 |
| 20130324664 | METHOD FOR IMPROVING REJECTION OF REVERSE OSMOSIS MEMBRANE, TREATMENT AGENT FOR IMPROVING REJECTION, AND REVERSE OSMOSIS MEMBRANE - A method capable of effectively improving a rejection of a reverse osmosis membrane without remarkably reducing a permeation flux, even if the membrane is seriously degraded. An aqueous solution containing a first organic compound having a molecular weight of less than 200, a second organic compound having a molecular weight of 200 to less than 500, and a third organic compound having a molecular weight of 500 or more is passed through the reverse osmosis membrane. The first organic compound is preferably an amino acid or an amino acid derivative. The total concentration of the first organic compound and the second organic compound and the concentration of the third organic compound are each preferably 1 to 500 mg/L. | 12-05-2013 |
| 20130331517 | Novel Polymer Derivative Of Cytidine Metabolic Antagonist | 12-12-2013 |
| 20140073738 | Hydrophilic Polymeric Particles and Methods for Making and Using Same - A method of forming a particle includes, in a disperse phase within an aqueous suspension, polymerizing a plurality of mer units of a hydrophilic monomer having a hydrophobic protection group, thereby forming a polymeric particle including a plurality of the hydrophobic protection groups. The method further includes converting the polymeric particle to a hydrophilic particle. | 03-13-2014 |
| 20140094568 | OUTER LAYER HAVING ENTANGLEMENT OF HYDROPHOBIC POLYMER HOST BLENDED WITH A MALEATED HYDROPHOBIC POLYMER CO-HOST, AND HYDROPHILIC POLYMER GUEST - The present disclosure provides, inter alia, a method of producing an outer layer material for forming into a structure and that comprises an entanglement having a hydrophobic polymer host and a hydrophilic guest, including in one embodiment the steps of: intermingling cloaked hydrophilic guest complexes with the hydrophobic host; crosslinking molecules of the guest with the guest; and performing a hydrolysis reaction. | 04-03-2014 |
| 20140350184 | SURFACE MODIFICATION OF POLYMERS VIA SURFACE ACTIVE AND REACTIVE END GROUPS - Polymer surface modification method comprising the steps of first forming a surface of primary reactive end groups tethered to the polymer chain ends during fabrication of an article, and then modifying the reactive surface with bio-active molecules, hydrophilic and hydrophobic monomers, oligomers, or polymers to attain specific surface properties. Alternatively, a multifunctional coupling agent can be used to couple the primary reactive group to a second reactive group capable of reacting with a functional group associated with bio-active molecules, hydrophilic and hydrophobic monomers, oligomers, and polymers to attain specific surface properties. The invention involves bringing reactive endgroups to the surface with surface active spacer attached to the polymer chain end. The surface active spacer allows the migration and enrichment of reactive end groups to the surface during fabrication. The invention provides medical devices having a bio-interface with anti-thrombogenic properties, lubricity, selective adsorption, and antimicrobial properties. | 11-27-2014 |
| 20150031833 | FORMYLPYRROLE-BASED HETEROCYCLES FOR NUCLEIC ACID ATTACHMENT TO SUPPORTS - A compound has Formula I: | 01-29-2015 |
| 20150045507 | CROSS-LINKED POLYMERS AND MEDICAL PRODUCTS DERIVED FROM NUCLEOPHILICALLY ACTIVATED POLYOXAZOLINE - One aspect of the invention relates to a biocompatible medical product comprising at least 1% by weight of dry matter of a covalently cross-linked polymer that is obtained by reacting a nucleophilically activated polyoxazoline (NU-POX) with an electrophilic cross-linking agent other than an electrophilically activated polyoxazoline, said NU-POX comprising m nucleophilic groups; and said electrophilic cross-linking agent comprising n electrophilic groups, wherein the m nucleophilic groups are capable of reaction with the n electrophilic groups to form covalent bonds; wherein m≧2, n≧2 and m+n≧5; and wherein the NU-POX comprises at least 30 oxazoline units in case the electrophilic cross-linking agent is an isocyanate. Also provided is a kit for producing the aforementioned biocompatible cross-linked polymer. The biocompatible cross-linked polymers according to the invention have excellent implant and/or sealing characteristics. | 02-12-2015 |
| 20150045508 | IMMOBILISED BIOLOGICAL ENTITIES - There is described inter alia a medical device having a surface which comprises a coating layer, said coating layer being a biocompatible composition comprising an entity capable of interacting with mammalian blood to prevent coagulation or thrombus formation, which entity is covalently attached to said surface through a link comprising a 1,2,3-triazole. | 02-12-2015 |
| 20150051347 | BLOCK COPOLYMER HAVING PHENYLBORONIC ACID GROUP INTRODUCED THEREIN, AND USE THEREOF - A block copolymer includes a polyamino acid chain segment and a hydrophilic polymer chain segment. The polyamino acid chain segment includes at least one amino acid residue having a side chain that contains a cationic group and at least one amino acid residue having a side chain that contains a substituted phenylboronic acid group. In the substituted phenylboronic acid group, at least one hydrogen of the phenyl ring is substituted so that the phenylboronic acid group has a pKa of less than 8. Such a block copolymer serves as a carrier that simultaneously imparts stability to a biotechnology-based drug in blood and provides suitable drug-releasing properties of the drug at an affected area. | 02-19-2015 |
| 20150141575 | CHARGE CONVERSIONAL TERNARY POLYPLEX - Disclosed is a polymer composite (polyplex) that contains nucleic acid, a cationic polymer, and an anionic polymer. The anionic polymer covers the surface of the composite comprising the cationic polymer and nucleic acid, has a negative charge at neutral pH, and can change so as to have a positive charge at mildly acidic pH. | 05-21-2015 |
| 20150290611 | COLLOIDS WITH VALENCE: FABRICATION, FUNCTIONALIZATION AND DIRECTIONAL BONDING - A method and articles of manufacture for creating colloidal clusters and functionalized patchy particles. The method includes selecting at least one type of colloidal particle, functionalizing a patch of the colloidal particle and mixing a plurality of the colloidal particles to construct a cluster with particular desired geometries properties based on the bonding of the colloidal particles by virtue of the patch having bond-type characteristic analogous to, but not limited to atomic orbitals and other symmetries. | 10-15-2015 |
| 20150367040 | IMMOBILISED BIOLOGICAL ENTITIES - There is described inter alia a device having a surface comprising a layered coating wherein the outer coating layer comprises a plurality of cationic hyperbranched polymer molecules characterized by having (i) a core moiety of molecular weight 14-1,000 Da (ii) a total molecular weight of 1,500 to 1,000,000 Da (iii) a ratio of total molecular weight to core moiety molecular weight of at least 80:1 and (iv) functional end groups, whereby one or more of said functional end groups have an anti-coagulant entity covalently attached thereto. | 12-24-2015 |
| 20160002723 | Conjugated Polymeric Particle and Method of Making Same - A method of conjugating a substrate includes exchanging a counter ion associated with a biomolecule with a lipophilic counter ion to form a biomolecule complex, dispersing the biomolecule complex in a nonaqueous solvent, and coupling the biomolecule complex to a substrate in the presence of the nonaqueous solvent. | 01-07-2016 |
| 20160096926 | Chemically Modified Dendrimers - Dendrimers comprising N-acyl urea terminal moieties are described herein. The dendrimers can be used, for example, in the treatment of arthritis. | 04-07-2016 |
| 20160122816 | NOVEL POLYMERS AND DNA COPOLYMER COATINGS - Some embodiments described herein relate to new polymer coatings for surface functionalization and new processes for grafting pre-grafted DNA-copolymers to surface(s) of substrates for use in DNA sequencing and other diagnostic applications. | 05-05-2016 |
| 20160137677 | FORMYLPYRROLE-BASED HETEROCYCLES FOR NUCLEIC ACID ATTACHMENT TO SUPPORTS - A compound has Formula I: | 05-19-2016 |
| 20160160012 | RESIN COMPOSITION AND GATE INSULATING FILM - A resin composition containing a resin (A) which contains a hydroxyl group and a cyanoalkyl group, an epoxy compound (B) which has two or more epoxy groups in its molecule, a curing agent (C) which has two or more hydroxyl groups in its molecule and has a hydroxyl value of 150 to 300 mgKOH/g, and a cross-linking agent (D) which has a structure represented by the general formula (1). | 06-09-2016 |
