| Entries |
| Document | Title | Date |
|---|
| 20090012205 | TRANSPARENT GEL AND CONTACT LENSE FROM THE SAME - A transparent gel is disclosed which has an interpenetrating polymer network of a copolymer containing a polysiloxane structure and a polycarbonate structure and a hydrophilic polymer obtained by polymerizing a hydrophilic monomer. The transparent gel is useful as a cultivation substrate, a container for storage and an ophthalmic material, comprising an easily synthesizable and purifiable silicon-containing resin, wherein a gel strength, transparency, oxygen permeability, birefringence and other characteristics are excellent. | 01-08-2009 |
| 20090018233 | Crosslink Agents and Dual Radical Cure Polymer - A synthetic route to polymers comprised of at least two monomers each with a very different reactivity ratio by using a corresponding crosslink agent for each monomer. Novel crosslink agents are described that provide for the copolymerization of at least one hydrophilic monomer with at least one lens monomer typically used to prepare materials for ophthalmic lenses. The new crosslink agents have a relatively high selectivity for the hydrophilic monomer and limited reactivity with the crosslink agent used to polymerize the lens monomer. | 01-15-2009 |
| 20090143499 | Actinically-crosslinkable silicone-containing block copolymers - The invention provide a new class of silicone-containing prepolymers containing poly(oxyalkylene) blocks, polysiloxane blocks, and actinically-crosslinkable groups which are acryl groups, thiol groups, ene-containing groups or combinations thereof. A preopolymr of the invention is prepared in a one-pot procedure according to the Micahel addition of thiol to electron deficient alkenes, such as α,β-unsaturated carbonyl compounds, without need for additional reaction step(s) to introduce actinically crosslinkable groups. The present invention is also related to silicone hydrogel contact lenses made from this class of silicone-containing prepolymers and to methods for making the silicone hydrogel contact lenses. | 06-04-2009 |
| 20090156708 | BIOMEDICAL DEVICES - Biomedical devices are provided herein which are formed from a polymerization product of a mixture comprising (a) a copolymer which is the reaction product of one or more polymerizable polyhydric alcohols and one or more polymerizable fluorine-containing monomers; and (b) a biomedical device-forming comonomer. | 06-18-2009 |
| 20090170976 | Polysiloxane-based prepolymer and hydrogel - A polysiloxane-based prepolymer of a three-dimensional network structure produced by hydrolysis-condensation of a first mixture having a tetra-alkoxysilane compound, an ethylenically unsaturated organosiloxane monomer, and a hydrophilic silicon-containing polyfunctional monomer. A hydrogel is prepared by polymerizing a second mixture having the aforesaid polysiloxane-based prepolymer, an acrylated silicon-containing monomer, and an ethylenically unsaturated hydrophilic monomer. | 07-02-2009 |
| 20090247662 | Contact Lens Material - A contact lens material which has high oxygen permeability and mechanical strength, and extremely small in an amount of remaining unpolymerized monomers, at the same time, low in a water absorption ratio and excellent in shape stability of a lens is provided. The contact lens material comprises a copolymer obtained by polymerizing copolymer components containing a particular silicone-containing monomer, wherein the total residual amount of unpolymerized monomer components remaining in the copolymer based on the copolymer is at most 3.5% by weight, an oxygen permeability coefficient of the copolymer is at least 130×10 | 10-01-2009 |
| 20090264552 | OPTICAL COMPOSITE MATERIAL AND OPTICAL ELEMENT - Provided is an optical synthetic resin composed of: a synthetic resin; and fine particles dispersed in the synthetic resin at a ratio of 0.1 vol % or more to 50 vol % or less, each having a maximum length of 1 nm or more to 30 nm or less, in which part of surfaces of the fine particles are modified with functional groups which themselves repel each other, and a distance between two arbitrary adjacent fine particles among the fine particles is in a range of 0.1 nm or more to 500 nm or less. The two arbitrary adjacent fine particles attract each other with an intermolecular force, thereby making it possible to provide an optical composite deviating from an additivity range. | 10-22-2009 |
| 20090264553 | Wettable Silicone Hydrogel Contact Lenses and Related Compositions and Methods - Silicone hydrogel contact lenses having ophthalmically acceptable surface wettabilities are obtained from pre-extracted polymerized silicone hydrogel contact lens products having relatively large amounts of removable or extractable materials. The silicone hydrogel contact lenses can be obtained from non-polar resin based contact lens molds and without surface treatments or an interpenetrating polymeric network of a polymeric wetting agent. Related lens products, polymerizable compositions, and methods are also described. | 10-22-2009 |
| 20100016463 | ABRASION-RESISTANT OPTICAL ARTICLE AND PROCESS FOR MANUFACTURING THEREOF - An optical article includes a transparent substrate and an abrasion-resistant layer appended to at least one surface of the substrate. The abrasion-resistant layer results from the reaction mixture of:
| 01-21-2010 |
| 20100113641 | UV/VISIBLE LIGHT ABSORBERS FOR OPHTHALMIC LENS MATERIALS - Benzotriazole UV/Visible light-absorbing monomers are disclosed. The UV/Vis absorbers are particularly suitable for use in intraocular lens materials. | 05-06-2010 |
| 20100120938 | POLYSILOXANE COPOLYMERS WITH TERMINAL HYDROPHILIC POLYMER CHAINS - The invention provides an actinically-crosslinkable linear polysiloxane copolymer. The actinically-crosslinkable polysiloxane copolymer can be used to prepare a silicone hydrogel contact lens having a hydrophilic surface without post-curing surface treatment. The invention is also related to a silicone hydrogel contact lens obtained from a lens-forming material including an actinically-crosslinkable polysiloxane copolymer of the invention and to a method for making an actinically-crosslinkable polysiloxane copolymer of the invention. In addition, the invention provides a non-crosslinkable linear polysiloxane copolymer capable of being used as a internal wetting agent which can render the surface of a silicone hydrogel contact lens hydrophilic. | 05-13-2010 |
| 20100120939 | SILICONE HYDROGEL MATERIALS WITH CHEMICALLY BOUND WETTING AGENTS - The invention provide a new class of silicone-containing prepolymers containing ethylenically unsaturated groups and latent UV-activated free radical generating moieties. This class of silicone-containing prepolymer is capable of being actinically crosslinked in the presence of one or more hydrophilic vinylic monomers to form a silicone hydrogel material with a hydrophilic surface without post curing surface treatment. The present invention is also related to silicone hydrogel contact lenses made from this class of silicone-containing prepolymers and a vinylic monomer having a latent UV-activated free radical generating moiety. | 05-13-2010 |
| 20100227944 | METHOD FOR PREPARING SILICONE HYDROGELS - The present invention provides a method and a formulation for consistently producing a silicone hydrogel material having relatively high oxygen permeability, relatively high ion permeability, and low modulus, and contact lenses prepared from a formulation of the invention or made of a silicone hydrogel material of the invention. | 09-09-2010 |
| 20100249265 | Scratch-resistant coatings with improved adhesion to inorganic thin film coatings - A scratch-resistant coating comprising a polymer including a functionalized polysilsesquioxane. The scratch-resistant coating is exposed to oxidizing conditions (e.g., ozone or ultraviolet light) that modify the surface chemistry of the coating to enhance adhesion to inorganic thin film coatings, such as antireflective coatings. | 09-30-2010 |
| 20100280146 | Forming clear, wettable silicone hydrogel articles without surface treatments - The present invention is a composition, which may be used to form contact lenses, comprising at least one silicone containing component, at least one hydrophilic component, at least one high molecular weight hydrophilic polymer and at least one diluent with an alpha value of about 0.5 to about 1 and a Hansen solubility parameter of less than about 10. | 11-04-2010 |
| 20100331443 | SILICONE HYDROGELS FORMED FROM SYMMETRIC HYDROXYL FUNCTIONALIZED SILOXANES - The present invention relates to a silicone hydrogel having at least about 20 weight % water, and formed from a reactive mixture comprising at least one non-reactive hydrophilic polymer and at least one symmetric, hydroxyl functionalized silicone monomer. Silicone hydrogels of the present invention may be formed from reaction mixtures which do not contain hydrophilic monomers. | 12-30-2010 |
| 20110003910 | VISIBLE LIGHT ABSORBERS FOR OPHTHALMIC LENS MATERIALS - Azo compounds that block visible light are disclosed. These light absorbers are particularly suitable for use in intraocular lens materials. | 01-06-2011 |
| 20110009519 | MONO ETHYLENICALLY UNSATURATED POLYMERIZABLE GROUP CONTAINING POLYCARBOSILOXANE MONOMERS - The present invention relates to polymeric compositions useful in the manufacture of biocompatible medical devices. More particularly, the present invention relates to certain monoethylenically unsaturated polymerizable group containing polycarbosiloxane monomers capable of polymerization to form polymeric compositions having desirable physical characteristics useful in the manufacture of ophthalmic devices. | 01-13-2011 |
| 20110015298 | PROCESS FOR MAKING CATIONIC HYDROPHILIC SILOXANYL MONOMERS - The present invention relates to polymeric compositions useful in the manufacture of biocompatible medical devices. More particularly, the present invention relates to certain cationic monomers capable of polymerization to form polymeric compositions having desirable physical characteristics useful in the manufacture of ophthalmic devices. Such properties include the ability to extract the polymerized medical devices with water. This avoids the use of organic solvents as is typical in the art. The polymeric compositions comprise polymerized cationic hydrophilic siloxanyl monomers prepared by the process disclosed herein. | 01-20-2011 |
| 20110046259 | UV-ABSORBERS FOR OPHTHALMIC LENS MATERIALS - UV absorbing monomers that are particularly useful in ophthalmic devices are disclosed. | 02-24-2011 |
| 20110077322 | Silicone Prepolymer Solutions - In one aspect, the invention relates to silicone prepolymer compositions comprising a silicone prepolymer and a solvent. A soluble silicone prepolymer can be provided having increased average silicon content, thereby attaining a desired oxygen permeability. A solvent can be provided with a desired balance between hydrophilicity and hydrophobicity by selection and modification of the solvent molecular structure, resulting in molded polymer films and articles that exhibit minimal or nonexistent eye irritation and exhibit highly transparent products. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. | 03-31-2011 |
| 20110166248 | COPOLYMER FOR ENHANCING THE wETTABILITY OF SILICONE HYDROGEL, SILICONE HYDROGEL COMPOSITION COMPRISING THE SAME AND OCULAR ARTICLE MADE THEREFROM - The present invention provides a reactive hydrophilic copolymer consisting essentially of units formed by ethylenically unsaturated hydrophilic monomers and units of formula (I) or (II) formed by ethylenically unsaturated monomers having alkoxy silane functional groups in a random order: | 07-07-2011 |
| 20110178202 | VISIBLE LIGHT ABSORBERS FOR OPHTHALMIC LENS MATERIALS - Azo compounds that block visible light are disclosed. These light absorbers are particularly suitable for use in intraocular lens materials. | 07-21-2011 |
| 20110230589 | SILICONE HYDROGEL, LENS FOR EYE AND CONTACT LENS - The present invention provides transparent silicone hydrogels with high acrylamide monomer content and an excellent balance between moisture content. | 09-22-2011 |
| 20110269869 | PRODUCTION OF OPHTHALMIC DEVICES BASED ON PHOTO-INDUCED STEP GROWTH POLYMERIZATION - The invention provide a new lens curing method for making hydrogel contact lenses. The new lens curing method is based on actinically-induced step-growth polymerization. The invention also provides hydrogel contact lenses prepared from the method of the invention and fluid compositions for making hydrogel contact lenses based on the new lens curing method. In addition, the invention provide prepolymers capable of undergoing actinically-induced step-growth polymerization to form hydrogel contact lenses. | 11-03-2011 |
| 20110275734 | NON-REACTIVE, HYDROPHILIC POLYMERS HAVING TERMINAL SILOXANES AND METHODS FOR MAKING AND USING THE SAME - The present invention relates to compositions comprising at least one stable, near-monodisperse, non-reactive hydrophilic polymer comprising in said polymer's backbone, a hydrophilic segment having a degree of polymerization of about 10 to about 1000, and a linear silicone segment at least one terminal end of said non-reactive hydrophilic polymer, wherein said silicone segment comprises between about 6 and about 200 siloxy units, and said non-reactive hydrophilic polymer is associated, via the linear silicone block with a silicone hydrogel. The non-reactive hydrophilic polymers may be incorporated into the formulation from which the silicone hydrogel is made or may be contacted with the silicone hydrogel post formation. | 11-10-2011 |
| 20110294914 | WETTABLE HYDROGELS COMPRISING ACYCLIC POLYAMIDES - The present invention relates to biomedical devices, and particularly contact lenses comprising a polymer having entangled therein at least one acyclic polyamide. | 12-01-2011 |
| 20110313077 | Polymer material, opthalmic lens and contact lens - Provided is a polymer material having superior water wettability and lubricity, and enabling persistence of the same by allowing the surfactant to be retained by the polymer material so as not to be gradually released. The present invention is directed to a polymer material including: | 12-22-2011 |
| 20120010321 | ACTINICALLY-CROSSLINKABLE SILICONE-CONTAINING BLOCK COPOLYMERS - The invention provide a new class of silicone-containing prepolymers containing poly(oxyalkylene) blocks, polysiloxane blocks, and actinically-crosslinkable groups which are acryl groups, thiol groups, ene-containing groups or combinations thereof. A preopolymer of the invention is prepared in a one-pot procedure according to the Michael addition of thiol to electron deficient alkenes, such as α,β-unsaturated carbonyl compounds, without need for additional reaction step(s) to introduce actinically crosslinkable groups. The present invention is also related to silicone hydrogel contact lenses made from this class of silicone-containing prepolymers and to methods for making the silicone hydrogel contact lenses. | 01-12-2012 |
| 20120022180 | BIOMEDICAL DEVICES - Biomedical devices such as silicone hydrogels formed from a polymerization product of a mixture comprising (a) a siloxane-containing homopolymer which has only one thio carbonyl thio fragment of a reversible addition fragmentation chain transfer (RAFT) agent; and (b) one or more biomedical device-forming comonomers are disclosed. | 01-26-2012 |
| 20120029111 | AMPHIPHILIC POLYSILOXANE PREPOLYMERS AND USES THEREOF - The present invention provides an amphiphilic polysiloxane prepolymer which comprises hydrophilic monomeric units derived from at least one hydrophilic vinylic monomer, polysiloxane crosslinking units derived from at least one polysiloxane crosslinker having at least two terminal ethylenically-unsaturated groups, dangling polysiloxane chains each of which is terminated with one ethylenically unsaturated group, and chain-transfer units derived from a chain transfer agent other than a RAFT agent. A prepolymer of the invention is suitable for making hydrogel contact lenses. The present invention is also related to hydrogel contact lenses made from an amphiphilic polysiloxane prepolymer of the invention and to processes for preparing an amphiphilic polysiloxane prepolymer of the invention and for making silicone hydrogel contact lenses. | 02-02-2012 |
| 20120041097 | SILICONE-CONTAINING PREPOLYMERS WITH DANGLING HYDROPHILIC POLYMER CHAINS - The invention provide a new class of silicone-containing prepolymers containing dangling hydrophilic polymer chains. This class of silicone-containing prepolymer is capable of being actinically crosslinked to form a silicone hydrogel material with a hydrophilic surface without post curing surface treatment. The present invention is also related to silicone hydrogel contact lenses made from this class of silicone-containing prepolymers and to methods for making the silicone hydrogel contact lenses. | 02-16-2012 |
| 20120046382 | PREPOLYMERS WITH DANGLING POLYSILOXANE-CONTAINING POLYMER CHAINS - The invention provide a new class of silicone-containing prepolymers containing dangling polysiloxane-containing polymer chains. This class of silicone-containing prepolymer is capable of being actinically crosslinked to form a silicone hydrogel material with a relatively high oxygen permeability, a reduced elastic modulus, and a relatively high ion permeability. The present invention is also related to silicone hydrogel contact lenses made from this class of silicone-containing prepolymers and to methods for making the silicone hydrogel contact lenses. | 02-23-2012 |
| 20120088861 | WATER-PROCESSABLE SILICONE-CONTAINING PREPOLYMERS AND USES THEREOF - The invention provide a class of water-processable polymerizable prepolymers which comprises (1) siloxane-containing monomeric units derived at least one siloxane containing monomer having one hydrophilic group or chain and/or polysiloxane-containing crosslinking units derived from at least one hydrophilized polysiloxane or chain-extended polysiloxane crosslinker; (2) hydrophilic monomeric units derived from one or more hydrophilic vinylic monomers; and (3) from about 0.05% to about 5% by weight of polymerizable units each having a pendant or terminal, ethylenically-unsaturated group and free of any polysiloxane segment. The prepolymer comprises from about 20% to about 50% by weight of silicone relative to the total weight of the prepolymer and has a high water solubility or dispersibility of at least about 5% by weight in water and suitable for making silicone hydrogel contact lenses. | 04-12-2012 |
| 20120115979 | CHLORINATED POLYMER ENHANCING WETTABILITY OF SILICONE HYDROGEL, SILICONE HYDROGEL COMPRISING THE SAME AND OCULAR ARTICLE MADE THEREFROM - The present invention provides a reactive hydrophilic polymer comprising units of Formulae (I) and (II): | 05-10-2012 |
| 20120115980 | SILICONE HYDROGEL REACTIVE MIXTURES COMPRISING BORATES - Disclosed in this specification is a method for forming a silicone hydrogel material that is useful for forming contact lens materials. The method includes using an effective amount of a borate additive to reduce the gel time of the silicone hydrogel reactive mixture and/or enhance the optical properties of the resulting cured material. | 05-10-2012 |
| 20120136087 | PHOSPHORYLCHOLINE-BASED AMPHIPHILIC SILICONES FOR MEDICAL APPLICATIONS - Amphiphilic biomimetic phosphorylcholine-containing silicone compounds for use in both topical and internal applications as components in biomedical devices. The silicone compounds, which include zwitterionic phosphorylcholine groups, may be polymerizable or non-polymerizable. Specific examples of applications include use as active functional components in ophthalmic lenses, ophthalmic lens care solutions, liquid bandages, wound dressings, and lubricious and anti-thrombogenic coatings. | 05-31-2012 |
| 20120202916 | Low-Tack, Hydrophobic Ophthalmic Device Materials - Disclosed are low-tack, hydrophobic, high refractive index, acrylic materials. These materials, especially useful as intraocular lens materials, contain one or more aryl acrylic hydrophobic monomers as principal device-forming monomers, a tack-reducing block copolymer additive and a glistening-reducing additive. In addition to their use as intraocular lens materials, the present materials are also suitable for use in other implantable ophthalmic devices. | 08-09-2012 |
| 20120214898 | SILICONE HYDROGEL WITH HIGH WATER CONTENT - The present invention provides a silicone hydrogel comprising a reaction product of a monomer mixture for forming the silicone hydrogel and water, wherein the water is present in an amount not less than 50 wt % based on the total weight of the silicone hydrogel. The monomer mixture comprises at least one silicon-containing monomer and at least one ionic monomer, wherein the ionic monomer is present in an amount not less than 0.7 wt % based on the total dry weight of the silicone hydrogel. The present invention also provides ocular articles made from the silicone hydrogel. | 08-23-2012 |
| 20120214899 | METHOD FOR ENHANCING WATER CONTENT OF SILICONE HYDROGEL CONTACT LENS - The present invention provides a method for producing a silicone hydrogel having a high water content. The method comprises the following steps:
| 08-23-2012 |
| 20120220688 | Phosphine-Containing Hydrogel Contact Lenses - Hydrogel contact lenses that are derived from a polymerizable composition including at least one hydrophilic monomer and at least one phosphine-containing component are described. The hydrogel of the contact lenses can be a silicone hydrogel or a non-silicone hydrogel. Use of polymerizable compositions comprising a phosphine-containing component can be cured under both inert and air atmospheres, and can be used to form hydrogel contact lenses having improved shape retention properties, having improved resistance to discoloration. Batches of hydrogel contact lenses and methods of making hydrogel contact lenses are also described. | 08-30-2012 |
| 20120220689 | Silicone Hydrogel Contact Lenses - Silicone hydrogel contact lenses that have good dimensional stability, are ophthalmically-acceptable, and can be manufactured without the use of alcohol solvents are formed from the reaction product of a polymerizable composition comprising at least one mono-functional acrylate-containing siloxane monomer having a molecular weight of less than 2,000; at least one bi-functional acrylate-containing siloxane monomer having a molecular weight of at least 3,000; and at least one hydrophilic vinyl-containing monomer, wherein the polymerizable composition has a molar ratio of total amount of mono-functional acrylate-containing siloxane monomer to total amount of bi-functional acrylate-containing siloxane monomer of at least 30:1, respectively. | 08-30-2012 |
| 20120220690 | Silicone Hydrogel Contact Lenses Having Acceptable Levels Of Energy Loss - Silicone hydrogel contact lenses having ophthalmically acceptable levels of energy loss are described. The lenses are derived from a polymerizable composition including a first siloxane monomer represented by formula (1): | 08-30-2012 |
| 20120245248 | SILICONE HYDROGELS FORMED FROM REACTION MIXTURES FREE OF HYDROPHILIC MONOMERS - The present invention relates to silicone hydrogels formed from mixtures comprising one or more hydrophilic high molecular weight polymers, one or more hydroxyl-functionalized silicone containing monomers, one or more crosslinkers and a compatabilizing diluent, but without a substantial amount of a reactive hydrophilic monomer or macromer. | 09-27-2012 |
| 20120252925 | Silicone Hydrogel Contact Lens - Ophthalmically compatible contact lenses include lens bodies configured for placement on a cornea of an animal or human eye. The lens bodies are made of a hydrophilic silicon-containing polymeric material. The lens bodies have oxygen permeabilities, water content, surface wettabilities, flexibilities, and/or designs to be worn by a lens wearer even during sleep. The present lenses can be worn on a daily basis, including overnight, or can be worn for several days, such as about thirty days, without requiring removal or cleaning. | 10-04-2012 |
| 20120277342 | METHACRYLATE-BASED BULKY SIDE-CHAIN SILOXANE CROSS LINKERS FOR OPTICAL MEDICAL DEVICES - Novel polymers for biomedical use, especially rigid gas permeable contact lenses that are based on bulky side-chain siloxane cross linkers. The siloxanes, either alone, or as copolymers with bulky and non-bulky mono-functional polymerizable siloxanes, fluoro monomers, such as hexafluoroisopropyl methacrylate, and hydrophilic monomers, result in transparent, high oxygen permeable polymers possessing excellent lathing and milling characteristics. | 11-01-2012 |
| 20120283353 | MEDICAL DEVICES HAVING HOMOGENEOUS CHARGE DENSITY AND METHODS FOR MAKING SAME - The present invention relates to ionic silicone hydrogel polymers displaying improved lysozyme uptake, low contact angle and reduced water soluble polymeric ammonium salt uptake. | 11-08-2012 |
| 20120302661 | Polymers for Contact Lenses - The present invention relates to a polyurethane prepared from a mixture comprising: (a) at least one polyethylene glycol; (b) at least one di-isocyanate; (c) at least one polydialkyl siloxane diol; and (d) at least one diol of formula (I) wherein n is an integer from 1 to 25; wherein the polyethylene glycol, di-isocyanate, polydialkyl siloxane diol and diol are reacted under substantially anhydrous conditions. Further aspects of the invention relate to a process for preparing a polyurethane. The invention also relates to a process for preparing a polyurethane xerogel in the form of a molded article, said process comprising the steps of: (i) preparing a reaction mixture comprising at least one polyethylene glycol, at least one di-isocyanate, at least one polydialkyl siloxane diol and at least one diol of formula I as described above; (ii) reacting the reaction mixture formed in step (i) under substantially anhydrous conditions to form a polyurethane xerogel; and (iii) injection molding the polyurethane xerogel to form a molded article. | 11-29-2012 |
| 20130046043 | Silicone Hydrogels and Methods of Manufacture - Embodiments of silicone hydrogels, ophthalmic lenses made therefrom, and methods of making the same are described. Fully hydrated silicone hydrogels have relatively high water content and oxygen permeability, along with relatively low modulus of elasticity. Embodiments of the silicone hydrogels in substantially dehydrated condition are adapted to lathe cutting at or above room temperature. Variations of the silicone hydrogels include silicon-containing monomers in an amount greater than 25% by weight, a hydrophilic substituted N-vinyl acetamide monomer in an amount greater than 30% by weight, and a hydrophilic non-acetamide monomer in an amount resulting in a hydrophilic substituted N-vinyl acetamide monomer to hydrophilic non-acetamide monomer weight to weight ratio of greater than 2.1 to 1. | 02-21-2013 |
| 20130085205 | SILICONE HYDROGELS HAVING IMPROVED CURING SPEED AND OTHER PROPERTIES - The present invention relates to: to a silicone polymer formed from reactive components containing (i) at least one silicone component and (ii) 2-hydroxyethyl acrylamide; a silicone hydrogel containing such silicone polymer; a biomedical device (e.g., a contact lens) containing such polymer; and a biomedical device formed from such hydrogel. | 04-04-2013 |
| 20130150482 | CONTACT LENSES - The invention provides silicone hydrogel contact lenses that exhibit reduced back surface debris and reduced incidence of superior epithelial arcurate lesions. | 06-13-2013 |
| 20130172440 | SILICONE HYDROGELS COMPRISING DESIRABLE WATER CONTENT AND OXYGEN PERMEABILITY - The present invention relates to a process comprising the steps of reacting a reactive mixture comprising at least one silicone-containing component, at least one hydrophilic component, and at least one diluent to form an ophthalmic device having an advancing contact angle of less than about 80°; and contacting the ophthalmic device with an aqueous extraction solution at an elevated extraction temperature, wherein said at least one diluent has a boiling point at least about 10° higher than said extraction temperature. | 07-04-2013 |
| 20130184372 | SILICONE POLYMERS COMPRISING SULFONIC ACID GROUPS - The present invention relates to a silicone polymer comprising a sulfonic acid component formed from reactive components comprising (i) at least one silicone component and (ii) at least one sulfonic acid-containing component, wherein the sulfonic acid-containing component is comprised of a non-polymerizable, hydrophobic cation and a polymerizable sulfonic acid. | 07-18-2013 |
| 20130197125 | MONO ETHYLENICALLY UNSATURATED POLYMERIZABLE GROUP CONTAINING POLYCARBOSILOXANE MONOMERS - The present invention relates to polymeric compositions useful in the manufacture of biocompatible medical devices. More particularly, the present invention relates to certain monoethylenically unsaturated polymerizable group containing polycarbosiloxane monomers capable of polymerization to form polymeric compositions having desirable physical characteristics useful in the manufacture of ophthalmic devices. | 08-01-2013 |
| 20130225715 | BIOMEDICAL DEVICES CONTAINING INTERNAL WETTING AGENTS - This invention includes a wettable biomedical device containing a high molecular weight hydrophilic polymer and a hydroxyl-functionalized silicone-containing monomer. | 08-29-2013 |
| 20130237631 | BIOMEDICAL DEVICES CONTAINING INTERNAL WETTING AGENTS - This invention includes a wettable biomedical device containing a high molecular weight hydrophilic polymer and a hydroxyl-functionalized silicone-containing monomer. | 09-12-2013 |
| 20130261215 | IONIC SILICONE HYDROGELS HAVING IMPROVED HYDROLYTIC STABILITY - The present invention relates to ionic silicone hydrogel polymers displaying improved thermal stability. More specifically, the present invention relates to a polymer formed from reactive components comprising at least one silicone component and at least one ionic component comprising at least one anionic group. The polymers of the present invention display good thermal stability and desirable protein uptake. | 10-03-2013 |
| 20130261216 | Silicone Hydrogel Contact Lenses Having Acceptable Levels Of Energy Loss - Silicone hydrogel contact lenses having ophthalmically acceptable levels of energy loss are described. The lenses are derived from a polymerizable composition including a first siloxane monomer represented by formula (1): | 10-03-2013 |
| 20130274371 | Silicone Hydrogels and Methods of Manufacture - Embodiments of silicone hydrogels, ophthalmic lenses made therefrom, and methods of making the same are described. Fully hydrated silicone hydrogels have relatively high water content and oxygen permeability, along with relatively low modulus of elasticity. Embodiments of the silicone hydrogels in substantially dehydrated condition are adapted to lathe cutting at or above room temperature. Variations of the silicone hydrogels include silicon-containing monomers in an amount of 7.5% or greater by weight, a hydrophilic substituted N-vinyl acetamide monomer, and a hydrophilic non-acetamide monomer in an amount resulting in a hydrophilic substituted N-vinyl acetamide monomer to hydrophilic non-acetamide monomer weight to weight ratio of greater than 2.1 to 1 | 10-17-2013 |
| 20130317131 | POLYMERS AND NANOGEL MATERIALS AND METHODS FOR MAKING AND USING THE SAME - Provided are compositions comprising a block copolymer of the following formula: [A]-B-[Q], wherein [A] is a polymer that has an affinity for a substrate; B is a linking group comprising an optionally-substituted, polyvalent linking group having a molecular weight of no more than 1000 g/mole; and [Q] comprises a semi-crosslinked, ungelled polymer derived from copolymerization of an ethylenically unsaturated monomer with a poly-functional ethylenically unsaturated monomer. Such block copolymers are cross-linked via the [Q] segment, but not macroscopically gelled. The [Q] segment is hydrophilic and has a degree of polymerization in the range of about 10 to about 10,000. The [A] segment is located on at least one terminal end of said block copolymer, comprises between about 1 and about 200 repeating units. The block copolymer is associated, via the linear substrate associative segment with a surface comprising at least one hydrophobic site, such as a silicone hydrogel. The polymers may be incorporated into a formulation from which the silicone hydrogel is made or may be contacted with the silicone hydrogel post-formation. | 11-28-2013 |
| 20130317132 | CONTACT LENSES COMPRISING WATER SOLUBLE N-2 HYDROXYALKYL) (METH)ACRYLAMIDE POLYMERS OR COPOLYMERS - The present invention relates to biomedical devices, and particularly contact lenses comprising a polymer having entangled therein at least one polymer comprising repeating units from N-(2-hydroxyalkyl)(meth)acrylamide. | 11-28-2013 |
| 20130317133 | POLYMERS AND NANOGEL MATERIALS AND METHODS FOR MAKING AND USING THE SAME - Provided are articles such as medical devices which comprise at least one water soluble, crosslinked copolymer. The primary polymer chains of the copolymer are hydrophilic and independently have a degree of polymerization in the range of about 10 to about 10,000. The water soluble, crosslinked copolymers of the present invention are free from terminal substrate associating segments. The copolymers may be incorporated into a formulation from which the article is made or may be contacted with the article post-formation. | 11-28-2013 |
| 20140018465 | High Water Content Silicone Hydrogel Contact Lenses - Silicone hydrogel contact lenses having a high water content are described. The lenses are derived from a polymerizable composition including a first siloxane monomer represented by formula (1): | 01-16-2014 |
| 20140024738 | Silicone Hydrogel Contact Lenses - Silicone hydrogel contact lenses are described. The lenses are derived from a polymerizable composition including 30-60 unit parts by weight of a hydrophilic monomer(s) having one N-vinyl group, 10 to 50 unit parts by weight of 2-hydroxyethyl methacrylate (HEMA), and a first siloxane monomer component comprising a siloxane monomer of formula (1) as described herein or a siloxane monomer of formula (2) as described herein or a siloxane monomer of formula (3) as described herein or any combination thereof, where the total amount of siloxane monomer(s) present in the polymerizable composition is from 15 to 40 unit parts by weight. Batches of silicone hydrogel contact lenses and methods of making silicone hydrogel contact lenses are also described. | 01-23-2014 |
| 20140031449 | SILICONE HYDROGELS FORMED FROM ZERO DILUENT REACTIVE MIXTURES - The present invention relates to silicone hydrogels having a desirable balance of properties which can be formed without diluents. The silicone hydrogels are formed from reactive mixtures comprising at least one hydroxyl substituted, monofunctional polydialkylsiloxane monomer having between 2 and 120 dialkylsiloxane repeating units, at least one slow reacting hydrophilic monomer and at least one hydroxyl containing hydrophilic monomer. | 01-30-2014 |
| 20140039086 | CURABLE COLORED INKS FOR MAKING COLORED SILICONE - The present invention provides an actinically or thermally curable ink for making colored silicone hydrogel contact lenses. The ink of the invention comprises at least one colorant, a solvent and a binder polymer including ethylenically unsaturated groups and segments derived from at least one silicone-containing vinylic monomer or macromer. The ink of the invention is characterized by having capability to be cured actinically or thermally to form a colored coat on a silicone hydrogel contact lens, wherein the colored coat has good adhesion to the silicone hydrogel contact lens without being covalently attached to the lens material of the contact lens. The invention also provides methods for making colored silicone hydrogel contact lenses. | 02-06-2014 |
| 20140066540 | Contact Lenses Made With HEMA-Compatible Polysiloxane Macromers - Optically clear silicone hydrogel contact lenses are described that comprise a polymeric lens body that is the reaction product of a polymerizable composition comprising at least 25 wt. % of at least one hydroxyalkyl methacrylate; and at least 20 wt. % of at least one HEMA-compatible bifunctional polysiloxane comprising at least 6 siloxane groups and having an HLB value of at least 5 and/or a hydroxyl group content of at least 1 wt. %. | 03-06-2014 |
| 20140155515 | SILICONE HYDROGEL COMPOSITION AND SILICONE HYDROGEL CONTACT LENSES MADE FROM THE COMPOSITION - A silicone hydrogel composition is disclosed. The composition includes at least one silicone macromer, a hydroxy-functionalized silicone-containing monomer, a first hydrophibic monomer and at least one crosslinker, in which the first hydrophibic monomer is N-vinyl pyrrolidone. The silicone macromer and the hydroxy-functionalized silicone-containing monomer are mutually soluble with N-vinylpyrrolidone. Silicone hydrogel contact lenses prepared from the silicone hydrogel composition are also disclosed. | 06-05-2014 |
| 20140163135 | HYDROPHILIC SILICONE MONOMERS, PROCESS FOR THEIR PREPARATION AND THIN FILMS CONTAINING THE SAME - There is provided new mono-(meth)acrylate functionalized hydrophilic silicone monomers containing a polyether with branched linking group, useful in making water absorbing silicone-hydrogel films for contact lens applications. This invention also provides homo-polymers and copolymers made from the mono-(meth)acrylate functionalized hydrophilic silicone monomers described herein. Also provided is a process for producing the monomers and polymers described herein and contact lenses produced from the same. | 06-12-2014 |
| 20140171541 | POLYMERIC ARTICLES COMPRISING OXYGEN PERMEABILITY ENHANCING PARTICLES - The present invention relates to a composition comprising a hydrogel polymer having less than 100% haze, and distributed therein an oxygen enhancing effective amount of oxygen permeable particles having an oxygen permeability of at least about 100 barrer, average particle size less than about 5000 nm. | 06-19-2014 |
| 20140171542 | AMPHIPHILIC SILOXANE-CONTAINING VINYLIC MONOMERS AND USES THEREOF - The invention provides an amphiphilic siloxane-containing vinylic monomer which comprises one sole ethylenically unsaturated group and a siloxane-containing group covalently linked to the ethylenically-unsaturated group through a hydrophilic linker. The present invention is also related to a polymer, an actinically-crosslinkable silicone-containing prepolymer, a silicone hydrogel polymeric material, or a silicone hydrogel contact lens, which comprises monomeric units derived from an amphiphilic siloxane-containing vinylic monomer of the invention. In addition, the invention provides a method for making silicone hydrogel contact lenses using a water-based lens-forming formulation comprising an amphiphilic siloxane-containing vinylic monomer of the invention and/or an actinically-crosslinkable silicone-containing prepolymer of the invention. | 06-19-2014 |
| 20140171543 | ACTINICALLY-CROSSLINKABLE AMPHIPHILIC PREPOLYMERS - The invention provide a class of actinically-crosslinkable amphiphilic prepolymers which comprise at least one polysiloxane segment, at least one polyoxazoline segment, and two terminal ene groups. The present invention is also related to a medical device comprising a silicone hydrogel material obtained from step-growth polymerization of a polymerizable material comprising a prepolymer of the invention and to a method for producing contact lenses from a prepolymer of the invention. | 06-19-2014 |
| 20140171544 | CONTACT LENS - A contact lens formed of a composition comprising the reaction product of: A) at least 10 weight percent, based on the total composition weight excluding solvent, of at least one silicone-containing monomer of the formula I: where n is from 1 to 3, m is from 9 to 15, each a independently is C | 06-19-2014 |
| 20140179824 | METHOD OF PREPARING WATER EXTRACTABLE SILICON-CONTAINING BIOMEDICAL DEVICES - A method of preparing a water extractable silicon-containing biomedical device is disclosed. The method involves curing a monomer mixture comprising one or more silicon-containing biomedical device-forming monomers in the presence of a diluent to produce a silicon-containing biomedical device; wherein the diluent comprises a boric acid ester of a C | 06-26-2014 |
| 20140179825 | Methods Of Manufacturing Contact Lenses For Delivery Of Beneficial Agents - Contact lenses comprising an ionic component are packaged with a beneficial cationic agent in a temperature-sensitive packaging solution and/or a low ionic strength packaging solution. | 06-26-2014 |
| 20140200286 | Silicone Hydrogel Contact Lenses - Silicone hydrogel contact lenses are provided which have reduced modulus and contact angle properties, and which have acceptable wettabilities for use in daily wear and extended or continuous wear applications. | 07-17-2014 |
| 20140200287 | Reactive Dyes For Contact Lenses - A method for preparing a polymerizable monomer-dye compound is provided in which a monomer, a reactive dye, and base are combined under substantially anhydrous reaction conditions to form the polymerizable monomer-dye compound, wherein the monomer comprises a pendant reactive group that covalently links to the reactive dye to form the monomer-dye compound. | 07-17-2014 |
| 20140221523 | MATERIAL FOR CONTACT LENSES, METHOD FOR MANUFACTURING CONTACT LENSES AND CONTACT LENSES OBTAINED THEREBY - The invention provides a material for contact lenses, including a first siloxane macromer with the number average molecular weight of about 1,000 to 10,000, wherein the first siloxane macromer has a crosslinking function and is represented by the following formula (I): | 08-07-2014 |
| 20140288206 | UV BLOCKER LOADED CONTACT LENSES - UV absorbing appliances, such as contact lenses, are prepared by including at least one UV absorbing compound in the appliances. UV absorbing compounds can be water insoluble and/or reside in UV absorbing nanoparticles having a mean diameter less than 10 nm. The UV absorbing nanoparticles incorporate into an appliance by polymerizing a monomer mixture containing the UV absorbing nanoparticles to form an appliance comprising the UV absorbing nanoparticles. The UV absorbing compounds or the UV absorbing nanoparticles incorporate into an appliance by placing the appliance in a solution of the UV absorbing compound or a dispersion of the UV absorbing nanoparticles in a non-aqueous solvent that swells the appliance. The UV absorbing compound or the UV absorbing nanoparticles infuse into the swollen appliance and are retained within the appliance upon removal of the non-aqueous solvent. | 09-25-2014 |
| 20140296368 | MACROINITIATOR CONTAINING HYDROPHOBIC SEGMENT - The present invention relates to macroinitiators comprising at least one hydrophobic segments in a molecule, wherein a molecular weight of the hydrophobic segment is 300 to 1800. The present invention further relates to block copolymers, wetting agent and polymeric materials having the block copolymers of the present invention associated with, which is suitable for medical devices, particularly for ophthalmic devices, including contact lenses, ophthalmic lenses, punctal plugs and artificial corneas. | 10-02-2014 |
| 20150011669 | HYDROPHILIC MACROMERS AND HYDROGELS COMPRISING THE SAME - A hydrophilic silicone macromer composition suitable for use in producing hydrogel polymer films from which biomedical devices such as contact lenses can be made. The hydrophilic silicone macromer comprises a polyether backbone comprising a silicone-containing pendant group. In one aspect, a hydrophilic silicone macromer is of the Formula 1: | 01-08-2015 |
| 20150011670 | POLYMERIZABLE AMIDO-CONTAINING ORGANOSILICON COMPOUNDS, SILICON-CONTAINING POLYMERS AND BIOMEDICAL DEVICES THEREFROM - There is provided a fast curing composition comprising an alpha, beta-unsaturated amido-containing organosilicon compound, useful in making water absorbing silicone-hydrogel films for biomedical devices, such as contact lens, and a process for producing these monomers. This invention also provides for hydrogels made from the alpha, beta-unsaturated amido-containing organosilicon compound described herein. | 01-08-2015 |
| 20150011671 | ORGANO-MODIFIED SILICONE POLYMERS AND HYDROGELS COMPRISING THE SAME - A hydrophilic silicone polymer composition suitable for use in producing hydrogel polymer films disclosed. In one aspect, a hydrophilic silicone monomer is of the Formula 1: | 01-08-2015 |
| 20150011672 | SILICONE HYDROGELS HAVING A STRUCTURE FORMED VIA CONTROLLED REACTION KINETICS - The present invention relates to a process comprising the steps of reacting a reactive mixture comprising at least one silicone-containing component, at least one hydrophilic component, and at least one diluent to form an ophthalmic device having an advancing contact angle of less than about 80°; and contacting the ophthalmic device with an aqueous extraction solution at an elevated extraction temperature, wherein said at least one diluent has a boiling point at least about 10° higher than said extraction temperature. | 01-08-2015 |
| 20150057389 | HYDROGEL AND SILICONE HYDROGEL DEVICES INCLUDING POLYMERIZED SURFACTANTS - A wettable hydrogel or a silicone hydrogel device includes a polymerized surfactant incorporated into the gel by addition to a gel, on average, of a single ethylenic functionality of the precursor polymerizable surfactant in the polymerization mixture. The attached polymerized surfactant provides improved lubricity to the hydrogel or silicone hydrogel device. Alternately, a wettable hydrogel or a silicone hydrogel device can be formed by soaking a preformed hydrogel or a silicone hydrogel device in a solution of the polymerizable surfactant and a radical initiator and promoting the polymerization of the polymerizable surfactant and available polymerizable groups on or in the device. The wettable hydrogel or a silicone hydrogel device can be a contact lens. | 02-26-2015 |
| 20150094395 | SILICONE HYDROGELS COMPRISING DESIRABLE WATER CONTENT AND OXYGEN PERMEABILITY - The present invention relates to a process comprising the steps of reacting a reactive mixture comprising at least one silicone-containing component, at least one hydrophilic component, and at least one diluent to form an ophthalmic device having an advancing contact angle of less than about 80°; and contacting the ophthalmic device with an aqueous extraction solution at an elevated extraction temperature, wherein said at least one diluent has a boiling point at least about 10° higher than said extraction temperature. | 04-02-2015 |
| 20150111983 | MATERIAL FOR CONTACT LENSES, METHOD FOR MANUFACTURING CONTACT LENSES AND CONTACT LENSES OBTAINED THEREBY - The method for manufacturing contact lenses includes the following steps. First, a first siloxane macromer, a second siloxane macromer, at least one hydrophilic monomer, an initiator and a solvent are mixed to form a mixture. Then the mixture is injected into a mold of contact lens and conducted by a thermal treatment or a UV irradiating treatment to form contact lenses. The number average molecular weight of the first siloxane macromer represented by the following formula (I), is 1,000 to 10,000 and the first siloxane macromer has a cross-linking function. | 04-23-2015 |
| 20150301228 | AMPHIPHILIC SILOXANE-CONTAINING (METH)ACRYLAMIDES AND USES THEREOF - The invention provides an amphiphilic siloxane-containing (meth)acrylamide which comprises one sole (meth)acrylamido group, one sole tris(trimethylsiloxy)silyl group, and one polyethylene glycol segment which is either dangling polymer chain or a hydrophilic linker between the (meth)acrylamido group and the tris(trimethylsiloxy)silyl group. The present invention is also related to a polymer, an actinically-crosslinkable silicone-containing prepolymer, a silicone hydrogel polymeric material, or a silicone hydrogel contact lens, which comprises monomeric units derived from an amphiphilic siloxane-containing (meth)acrylamido group, one tris(trimethylsiloxy)silyl group of the invention. In addition, the invention provides a method for making silicone hydrogel contact lenses using a water-based lens-forming formulation comprising an amphiphilic siloxane-containing (meth)acrylamido group, one tris(trimethylsiloxy)silyl group of the invention and/or an actinically-crosslinkable silicone-containing prepolymer of the invention. | 10-22-2015 |
| 20150309210 | HYDROPHILIZED CARBOSILOXANE VINYLIC MONOMERS - The invention provides a hydrophilized carbosiloxane vinylic monomer which comprises (1) a poly(carbosiloxane) segment, (2) one sole ethylenically unsaturated group, and (3) at least one terminal or pendant group which is a hydrophilic group or hydrophilic polymer chain. The present invention is also related to a polymer, an actinically-crosslinkable silicone-containing prepolymer, a silicone hydrogel polymeric material, or a silicone hydrogel contact lens, which comprises monomeric units derived from a hydrophilized carbosiloxane vinylic monomer of the invention. | 10-29-2015 |
| 20150309211 | CARBOSILOXANE VINYLIC MONOMERS - The invention provides a carbosiloxane vinylic monomer which comprises one sole ethylenically unsaturated group, one sole terminal butyl group; and one oligo(carbosiloxane)-containing linkage between the ethylenically unsaturated terminal group and the terminal butyl group. The present invention is also related to a polymer, an actinically-crosslinkable silicone-containing prepolymer, a silicone hydrogel polymeric material, or a silicone hydrogel contact lens, which comprises monomeric units derived from a carbosiloxane vinylic monomer of the invention. | 10-29-2015 |
| 20150309212 | 3D NETWORK-STRUCTURED SILICON-CONTAINING PREPOLYMER AND METHOD FOR FABRICATING THE SAME - A 3D network-structured silicon-containing preploymer and a method for fabricating the same are disclosed. The method of the present invention undertakes a hydrolytic condensation/polymerization reaction of penta(alkynol)alkoxy solixane, a reactive silicon-containing polymer and a reactive hydrophilic monomer to form a silicon-containing preploymer featuring a 3D network structure and having superior mechanical strength. The method further undertakes a copolymerization reaction of the silicon-containing preploymer, a hydrophilic monomer and a silicon-containing hydrophobic monomer to fabricate a silicone hydrogel-containing mixture having high oxygen permeability and high hydrophilicity. The silicone hydrogel-containing mixture can be used to fabricate contact lenses that the users wear comfortably. | 10-29-2015 |
| 20150309213 | AMPHIPHILIC SILOXANE-CONTAINING VINYLIC MONOMERS AND USES THEREOF - The invention provides an amphiphilic siloxane-containing vinylic monomer which comprises one sole ethylenically unsaturated group and a siloxane-containing group covalently linked to the ethylenically-unsaturated group through a hydrophilic linker. The present invention is also related to a polymer, an actinically-crosslinkable silicone-containing prepolymer, a silicone hydrogel polymeric material, or a silicone hydrogel contact lens, which comprises monomeric units derived from an amphiphilic siloxane-containing vinylic monomer of the invention. In addition, the invention provides a method for making silicone hydrogel contact lenses using a water-based lens-forming formulation comprising an amphiphilic siloxane-containing vinylic monomer of the invention and/or an actinically-crosslinkable silicone-containing prepolymer of the invention. | 10-29-2015 |
| 20150315213 | TRIS(TRIMETHYL SILOXY)SILANE VINYLIC MONOMERS AND USES THEREOF - The invention provides a TRIS-containing vinylic monomer which comprises one sole (meth)acryloyloxy group and a tris(trimethylsiloxy)silyl group covalently linked to the ethylenically-unsaturated group through a polyoxyethylene linker. The present invention is also related to a polymer, an actinically-crosslinkable silicone-containing prepolymer, a silicone hydrogel polymeric material, or a silicone hydrogel contact lens, which comprises monomeric units derived from a TRIS-containing vinylic monomer of the invention. In addition, the invention provides a method for making a TRIS-containing vinylic monomer of the invention. | 11-05-2015 |
| 20150368404 | WATER SOLUBLE SILICONE MATERIAL - A water soluble silicone macromer comprising a siloxane backbone having grafted thereto a suitable number of hydrophilic groups to render the macromer water soluble, the macromer comprising a polymerizable functional group grafted to the siloxane backbone. In one aspect, the present invention provides a water soluble silicone macromer having a structure of Formula (1): where M is a hydrophilic group or segment; L is a hydrophilic or hydrophobic linkage; N is a hydrophilic or hydrophobic group or segment. Q is a polymerizable functional group; x is zero or an integer greater than zero; y is zero or an integer greater than zero; v is zero or an integer greater than zero; and z is greater than zero, with the proviso that both y and v are not zero. | 12-24-2015 |
| 20150369961 | SILICONE HYDROGELS COMPRISING N-VINYL AMIDES AND HYDROXYALKYL (METH)ACRYLATES OR (METH)ACRYLAMIDES - The present invention relates to a process comprising the steps of reacting a reactive mixture comprising at least one silicone-containing component, at least one hydrophilic component, and at least one diluent to form an ophthalmic device having an advancing contact angle of less than about 80°; and contacting the ophthalmic device with an aqueous extraction solution at an elevated extraction temperature, wherein said at least one diluent has a boiling point at least about 10° higher than said extraction temperature. | 12-24-2015 |
| 20150369962 | ACTINICALLY-CROSSLINKABLE AMPHIPHILIC PREPOLYMERS - The invention provide a class of actinically-crosslinkable amphiphilic prepolymers which comprise at least one polysiloxane segment, at least one polyoxazoline segment, and two terminal ene groups. The present invention is also related to a medical device comprising a silicone hydrogel material obtained from step-growth polymerization of a polymerizable material comprising a prepolymer of the invention and to a method for producing contact lenses from a prepolymer of the invention. | 12-24-2015 |
| 20150378057 | MEDICAL DEVICES HAVING HOMOGENEOUS CHARGE DENSITY AND METHODS FOR MAKING SAME - The present invention relates to ionic silicone hydrogel polymers displaying improved lysozyme uptake, low contact angle and reduced water soluble polymeric ammonium salt uptake. | 12-31-2015 |
| 20160003980 | Silicone Hydrogel Contact Lenses - A method is provided for manufacturing ophthalmically-acceptable, distortion-free silicone hydrogel contact lenses without the use of volatile organic solvents in the manufacturing process. The contact lenses are extract with an extraction liquid comprising an aqueous solution of a non-volatile organic solvent, such as ethyl lactate. | 01-07-2016 |
| 20160046801 | SILICONE HYDROGEL CONTACT LENS AND METHOD FOR MANUFACTURING THE SAME - The present invention discloses a method for manufacturing a silicone hydrogel, including the steps of preparing a polyethylene glycol-containing secondary or tertiary amino alcohol, a crosslinking agent having at least two epoxide rings, and a copolymerization mixture capable of performing a radical chain polymerization reaction, wherein the copolymerization mixture contains a linear silicone prepolymer, a silicone monomer, and a hydrophilic monomer, the linking process is activated, by heating to let the epoxide rings of the crosslinking agent open and respectively links with the amino alcohol and an one component of the copolymerization mixture, and completing the radical chain polymerization reaction to obtain a silicone hydrogel. The present invention also provides a contact lens manufactured by the aforementioned method. The present invention distributes and affixes polyethylene glycol of the amino alcohol onto the surface of the silicone hydrogel, thus providing hydrophilicity and electrical charges to the silicone hydrogel. | 02-18-2016 |
| 20160090432 | POLYMERIZABLE POLYSILOXANES WITH HYDROPHILIC SUBSTITUENTS - The invention provides an actinically-polymerizable amphiphilic polysiloxane which comprises a polysiloxane polymer chain comprising a polylsiloxane segments comprising at least one siloxane unit having a low molecular weight hydrophilic polymer chain connected with a silicone atom of the siloxane unit, and (meth)acrylamido groups each covalently bonded to one of the ends of the polysiloxane polymer chain and/or to the end of one of low molecular weight hydrophilic polymer chains each connected with one silicone atom. The present invention is also related to a polymer, an actinically-crosslinkable silicone-containing prepolymer, a silicone hydrogel polymeric material, or a silicone hydrogel contact lens, which comprises repeating units derived from an actinically-polymerizable amphiphilic polysiloxane of the invention. In addition, the invention provides a method for making silicone hydrogel contact lenses using a water-based lens-forming formulation comprising an actinically-polymerizable amphiphilic polysiloxane of the invention and/or an actinically-crosslinkable silicone-containing prepolymer of the invention. | 03-31-2016 |
| 20160103248 | SILICONE HYDROGELS HAVING DESIRABLE WATER CONTENT AND OXYGEN PERMEABILITY - The present invention relates to a process comprising the steps of reacting a reactive mixture comprising at least one silicone-containing component, at least one hydrophilic component, and at least one diluent to form an ophthalmic device having an advancing contact angle of less than about 80°; and contacting the ophthalmic device with an aqueous extraction solution at an elevated extraction temperature, wherein said at least one diluent has a boiling point at least about 10° higher than said extraction temperature. | 04-14-2016 |
| 20160161639 | CONTACT LENSES COMPRISING WATER SOLUBLE N-(2 HYDROXYALKYL) (METH)ACRYLAMIDE POLYMERS OR COPOLYMERS - The present invention relates to biomedical devices, and particularly contact lenses comprising a polymer having entangled therein at least one polymer comprising repeating units from N-(2-hydroxyalkyl)(meth)acrylamide. | 06-09-2016 |
| 20160194497 | MACROINITIATOR CONTAINING HYDROPHOBIC SEGMENT | 07-07-2016 |
