Entries |
Document | Title | Date |
20080200558 | Inhibitory or blocking agents of molecular generating and/or/ inducing functions - A method for inhibiting or blocking molecular generating and/or inducing functions of molecules using an inhibitory or blocking agent of the formula: | 08-21-2008 |
20080312334 | CYCLOHEXENONE COMPOUNDS FROM ANTRODIA CAMPHORATA TO TREAT AUTOIMMUNE DISEASES - The present invention relates to a compound of | 12-18-2008 |
20080312335 | LIVER PROTECTION COMPOUNDS OF THE CYCLOHEXENONE TYPE FROM ANTRODIA CAMPHORATA - The present invention relates to a compound of | 12-18-2008 |
20080312336 | Preventive and/or Therapeutic Agent for Diabetic Vascular Disorder and Respiratory Disorder - The present invention provides preventive and/or therapeutic agents for either one, or both, of a diabetic vascular disorder and a diabetic respiratory disorder comprising, as an active ingredient, a cyclohexenone long chain alcohol compound represented by the following formula (1): | 12-18-2008 |
20090030087 | Extracts derived from chenopodium plants and uses thereof - The present invention relates to pesticides. More particularly, the present invention relates to botanical pesticides. In particular, the present invention relates to compositions and methods for controlling plant-infesting pests with plant extracts and notably with compositions comprising oil extracts derived from | 01-29-2009 |
20090076169 | Differential evaporation potentiated disinfectant system - Antimicrobial compositions and methods of using such antimicrobial compositions to provide a reduction in populations of viable microorganisms. | 03-19-2009 |
20090239953 | USE OF AN ANTI-CANCER COMPOUND - The present invention relates to a compound represented by the formula (I), method of preparation, pharmaceutical preparation containing said compound, and the use of said compound in the manufacture of a pharmaceutical preparation for the prevention and treatment of cancer by way of inhibiting the proliferation of carcinoma cells of the cervix and ovaries. | 09-24-2009 |
20090298950 | CYCLOPENTANE/CYCLOPENTENE ALDEHYDE OR KETONE DERIVATIVES AND THEIR USE AS ODORANTS - The present invention relates to campholytic aldehyde condensates of formula (I) | 12-03-2009 |
20090306218 | Antimicrobial formulations - An antimicrobial formulation containing a synergistic combination of a quinone, such as an optionally substituted benzoquinone or hydroquinone, and a bismuth salt. The formulation may in particular be used against propionibacteria, more particularly to treat skin and skin structure conditions such as acne, or against microbial infections within the oral cavity. | 12-10-2009 |
20100076090 | Topical skin care formulations - A topical anti-aging skin care formulation comprising an effective amount of a benzoquinone, such as CoQ10, plus a synergistic pair of stabilizers and a synergistic pair of whiteners. The stabilizers are octyl salicylate and octyl methoxycinnamate. The whiteners are titanium dioxide and zinc oxide. When proper amounts of these ingredients are used in an aqueous based emulsion formulation, the product will be initially white, and will remain white for an extended period of time. | 03-25-2010 |
20100093870 | HERBAL MEDICAMENTS FOR THE TREATMENT OF NEUROCEREBROVASCULAR DISORDERS - The present invention relates to A composition obtained from the lipid soluble extract of rhizomes and leaves of | 04-15-2010 |
20100130619 | PHARMACEUTICAL COMPOSITION FOR PARENTERAL ADMINISTRATION OF IDEBENONE - The invention describes use of an injectable form of Idebenone, suitable for intravenous injection or infusion. The proposed formulation is an oil-in-water emulsion, where Idebenone is associated with the oil droplets. | 05-27-2010 |
20100144888 | PESTICIDAL METHODS AND COMPOSITIONS FOR MODULATING GABA RECEPTORS - Methods for using pesticidal compositions containing a pesticidally acceptable carrier, at least one GABA receptor modulator compound as a pesticidally active ingredient and optionally an additional compounds, such as a synergist, and methods for using same. | 06-10-2010 |
20100168249 | COMPOSITION CONTAINING REDUCED COENZYME Q10, AND METHOD FOR STABILIZING THE COMPOSITION - The invention provides a composition containing reduced coenzyme Q | 07-01-2010 |
20100273893 | PROTECTIVE EFFECT OF THYMOQUINONE IN SPESIS - The present invention refers to thymoquinone, a main constituent of the volatile oil of | 10-28-2010 |
20100273894 | TREATMENT OF LEBER'S HEREDITARY OPTIC NEUROPATHY AND DOMINANT OPTIC ATROPHY WITH TOCOTRIENOL QUINONES - The present invention relates to methods of treating Leber's hereditary optic neuropathy and dominant optic atrophy with tocotrienol quinones, including alpha-tocotrienol quinone, in order to alleviate symptoms of the disease. | 10-28-2010 |
20100280130 | QUINONE DERIVATIVE 2,3-DIMETHOXY-5-METHYL-6-(10-HYDROXYDECYL)-1,4-BENZOQUINONE FOR THE TREATMENT OF PRIMARY PROGRESSIVE MULTIPLE SCLEROSIS - The present invention relates to approaches, methods, pharmaceuticals and uses directed to the curative treating or preventing of Primary Progressive Multiple Sclerosis (PP-MS), by using 2,3-dimethoxy-5-methyl-6-(10-hydroxydecyl)-1,4-benzoquinone (Idebenone) as the active agent. | 11-04-2010 |
20100317742 | COMPOSITIONS AND METHODS FOR CONTROLLING A HONEY BEE PARASITIC MITE - As described below, the present invention provides methods and compositions for controlling a honey bee parasitic mite. In addition, the invention features compositions useful for the treatment or prevention of a parasitic mite infestation in a honey bee hive. | 12-16-2010 |
20110009494 | Inhibition of the Survival of Pancreatic Cancer by Cyclohexenone Compounds from Antrodia Camphorata - The present invention relates to a novel application of a compound. The compound 4-hydroxy-2,3-dimethoxy-6-methyl-5-(3,7,11-trimethyl-dodeca-2,6,10-trienyl)-cyclohex-2-enone of the invention is isolated and purified from the extracts of | 01-13-2011 |
20110009495 | Inhibition of the Survival of Bone Cancer by Cyclohexenone Compounds from Antrodia Camphorata - The present invention relates to a novel application of a compound. The compound 4-hydroxy-2,3-dimethoxy-6-methyl-5-(3,7,11-trimethyl-dodeca-2,6,10-trienyl)-cyclohex-2-enone of the invention is isolated and purified from the extracts of | 01-13-2011 |
20110021638 | MODULATION OF INFLAMMATION BY HOPS FRACTIONS AND DERIVATIVES - A natural formulation of compounds that would to modulate inflammation is disclosed. The formulation would also inhibit expression of COX-2, inhibit synthesis of prostaglandin selectively in target cells, and inhibit inflammatory response selectively in target cells. The compositions containing at least one fraction isolated or derived from hops. | 01-27-2011 |
20110060055 | Inhibition of the Survival of Lymphoma by Cyclohexenone Compounds from Antrodia Camphorata - The present invention relates to a novel application of a compound. The compound 4-hydroxy-2,3-dimethoxy-6-methyl-5-(3,7,11-trimethyl-dodeca-2,6,10-trienyl)-cyclohex-2-enone of the invention is isolated and purified from the extracts of | 03-10-2011 |
20110060056 | Inhibition of the Survival of Gastric Cancer by Cyclohexenone Compounds from Antrodia Camphorata - The present invention relates to a novel application of a compound. The compound 4-hydroxy-2,3-dimethoxy-6-methyl-5-(3,7,11-trimethyl-dodeca-2,6,10-trienyl)-cyclohex-2-enone of the invention is isolated and purified from the extracts of | 03-10-2011 |
20110060057 | Inhibition of the Survival of Skin Cancer by Cyclohexenone Compounds from Antrodia Camphorata - The present invention relates to a novel application of a compound. The compound 4-hydroxy-2,3 -dimethoxy-6-methyl-5-(3,7,11-trimethyl-dodeca-2,6,10-trienyl)-cyclohex-2-enone of the invention is isolated and purified from the extracts of | 03-10-2011 |
20110060058 | Inhibition of the Survival of Ovarian Cancer by Cyclohexenone Compounds from Antrodia Camphorata - The present invention relates to a novel application of a compound. The compound 4-hydroxy-2,3-dimethoxy-6-methyl-5-(3,7,11-trimethyl-dodeca-2,6,10-trienyl)-cyclohex-2-enone of the invention is isolated and purified from the extracts of | 03-10-2011 |
20110060059 | Inhibition of the Survival of Bladder Cancer by Cyclohexenone Compounds from Antrodia Camphorata - The present invention relates to a novel application of a compound. The compound 4-hydroxy-2,3-dimethoxy-6-methyl-5-(3,7,11-trimethyl-dodeca-2,6,10-trienyl)-cyclohex-2-enone of the invention is isolated and purified from the extracts of | 03-10-2011 |
20110065804 | ELECTRODEPOSITED METALLIC FINISHES INCLUDING ANTIMICROBIAL AGENTS - Articles having metallic finishes including antimicrobial agents dispersed throughout the finish and methods of electroplating said metallic finishes on a material. The metallic finishes include highly-decorative electroplated finishes for bathroom and kitchen hardware, door hardware, and other highly lustrous products where antimicrobial protection is preferred. | 03-17-2011 |
20110136917 | TETRAHYDRO-ISOALPHA ACID COMPOSITIONS AND METHODS FOR WEIGHT MANAGEMENT - Compositions and methods to promote or maintain weight loss utilizing tetrahydro-isoalpha acid compounds are disclosed. Methods to increase synthesis of GLP-1 are disclosed. | 06-09-2011 |
20110172312 | TREATMENT OF LEIGH SYNDROME AND LEIGH-LIKE SYNDROME WITH TOCOTRIENOL QUINONES - The present invention relates to methods of treating Leigh Syndrome and Leigh-like Syndrome with tocotrienol quinones, including alpha-tocotrienol quinone, in order to alleviate symptoms of the disease. | 07-14-2011 |
20110207829 | CONTROL OF TERMITES, FIRE ANTS AND CARPENTER ANTS - Carvone, linalool, styralyl alcohol and tetrahydrolinalool are effective for the control of termites, fire ants and carpenter ants. | 08-25-2011 |
20110275721 | METHOD FOR THE PURIFICATION OF SUBSTITUTED CYCLOPENT-2-EN-1-ONE CONGENERS AND SUBSTITUTED 1,3-CYCLOPENTADIONE CONGENERS FROM A COMPLEX MIXTURE USING COUNTERCURRENT SEPARATION - Methods of purifying individual congeners of substituted cyclohexa-2,4-dienones, substituted cyclohexane-1,3,5-triones, substituted cyclopent-2-en-1-ones, and substituted 1,3-cyclopentadiones and compositions using the same are disclosed. The purification method includes the steps of: (a) selecting a congener to be isolated; (b) dissolving the mixture of congeners in a bi-phasic solvent system specific to the selected congener to be isolated, wherein said bi-phasic system has a partition coefficient from about 0.5 to 5.0; (c) subjecting the mixture dissolved in the bi-phasic solvent system to a counter current chromatography; and (d) isolating the selected congener in substantially pure form. | 11-10-2011 |
20110319495 | Pharmaceutical Composition for Hepatitis Treatment and Applications - A pharmaceutical composition for hepatitis treatment, which comprises lucidone as an active ingredient; and a pharmaceutical acceptable carrier. As lucidone is a natural cyclopentenedione, the pharmaceutical composition of present invention has lesser side effects. The present invention is also related to the application of the pharmaceutical composition. | 12-29-2011 |
20120101169 | METHODS OF PROVIDING ANTICOAGULATION EFFECTS IN SUBJECTS - The present invention is directed to methods of providing anticoagulation effects in subjects in need thereof, comprising administering to the subjects at least twice a day compounds of the present invention, stereoisomers, and racemates thereof. | 04-26-2012 |
20120108671 | CIS 3,4-DIHYDROXY-2-(3-METHYLBUTANOYL)-5-(3-METHYLBUTYL)-4-(4-METHYLPENTAN- OYL)CYCLOPENT-2-EN-1-ONE DERIVATIVES, SUBSTANTIALLY ENANTIOMERICALLY PURE COMPOSITIONS AND METHODS - The present application provides cis 3,4-dihydroxy-2-(3-methylbutanoyl)-5-(3-methylbutyl)-4-(4-methylpentanoyl)cyclopent-2-en-1-one derivatives and substantially enantiomerically pure compositions thereof. These derivatives include (+)-(4S,5R)-3,4-dihydroxy-2-(3-methylbutanoyl)-5-(3-methylbutyl)-4-(4-methylpentanoyl)cyclopent-2-en-1-one, (−)-(4R,5S)-3,4-dihydroxy-2-(3-methylbutanoyl)-5-(3-methylbutyl)-4-(4-methylpentanoyl)cyclopent-2-en-1-one, and salts and crystals thereof. The application further provides methods of using the disclosed compounds and compositions to activate PPARγ, activate GPR120, inhibit inflammation, and treat conditions responsive to PPARγ modulation, conditions responsive to GPR120 modulation, and metabolic disturbances such as diabetes. | 05-03-2012 |
20120122994 | INSECTICIDAL COMPOUND - An object of the present invention is to provide a new insecticidal compound by paying attention to the insecticidal activity contained in the flower part of marigold, and to provide an insecticide containing the compound as an active ingredient. There are provided an insecticidal compound represented by the following chemical formula: [Formula 1], and an insecticide containing the insecticidal compound as an active ingredient or an insecticide containing, as active ingredients, the insecticidal compound and an insecticidal compound represented by the following chemical formula: [Formula 2], wherein the insecticide can exhibit extraordinary insecticidal efficacy compared with existing pyrethroid-based insecticidal compounds. | 05-17-2012 |
20120136068 | AMELIORANT FOR RENAL INSUFFICIENCY - The present invention relates to an agent for improving renal dysfunction comprising as an active ingredient a compound represented by the following formula (1): | 05-31-2012 |
20120232160 | Materials and Methods for Pest Control - The present invention provides a novel insecticide formulation that not only demonstrates strong insecticidal and residual activity against a variety of insects, but also exhibits low mammalian toxicity. | 09-13-2012 |
20120270950 | ALKALINE DECOMPOSITION PRODUCT OF HOP EXTRACT AND USE THEREOF - According to the present invention, there are provided a food and a food additive obtained using an alkaline decomposition product of a hop extract, and an agent for suppressing fat accumulation or for suppressing weight gain comprising the same as an active ingredient. | 10-25-2012 |
20120270951 | NOVEL ANTI-INFLAMMATORY CYCLOOXYGENASE INHIBITORS - Disclosed is a pharmaceutical composition including a therapeutic quantity of a COX-2 inhibitor having an IC50-WHMA COX-2/COX-1 ratio ranging from about 0.23 to about 3.33 with reduced gastrointestinal and cardiovascular toxicity. Also disclosed are methods for treating osteoarthritis, rheumatoid arthritis or acute pain with less side-effects and faster onset of action utilizing the disclosed pharmaceutical composition. | 10-25-2012 |
20120277320 | INHIBITION OF THE SURVIVAL OF SKIN CANCER BY CYCLOHEXENONE COMPOUNDS FROM ANTRODIA CAMPHORATA - The present invention relates to a novel application of a compound. The compound 4-hydroxy-2,3-dimethoxy-6-methyl-5-(3,7,11-trimethyl-dodeca-2,6,10-trienyl)-cyclohex-2-enone of the invention is isolated and purified from the extracts of | 11-01-2012 |
20120295985 | METHODS FOR IMPROVING BLOOD GLUCOSE CONTROL - The present invention is concerned with a method for improving blood glucose control or for preventing or treating a condition requiring increasing insulin sensitivity or reducing insulin resistance in a subject in need of such control which comprises administering to the subject a composition comprising a therapeutically effective amount of one or more quinones of Formula I. | 11-22-2012 |
20120322890 | Inhibition of the Survival of Bone Cancer by Cyclohexenone Compounds from Antrodia Camphorata - The present invention relates to a novel application of a compound. The compound 4-hydroxy-2,3-dimethoxy-6-methyl-5-(3,7,11-trimethyl-dodeca-2,6,10-trienyl)-cyclohex-2-enone of the invention is isolated and purified from the extracts of | 12-20-2012 |
20130005825 | Inhibition of the Survival of Lymphoma by Cyclohexenone Compounds from Antrodia Camphorata - The present invention relates to a novel application of a compound. The compound 4-hydroxy-2,3-dimethoxy-6-methyl-5-(3,7,11-trimethyl-dodeca-2,6,10-trienyl)-cyclohex- | 01-03-2013 |
20130005826 | Inhibition of the Survival of Gastric Cancer by Cyclohexenone Compounds from Antrodia Camphorata - The present invention relates to a novel application of a compound. The compound 4-hydroxy-2,3-dimethoxy-6-methyl-5-(3,7,11-trimethyl-dodeca-2,6,10-trienyl)-cyclohex-2-enone of the invention is isolated and purified from the extracts of | 01-03-2013 |
20130005827 | Inhibition of the Survival of Bladder Cancer by Cyclohexenone Compounds from Antrodia Camphorata - The present invention relates to a novel application of a compound. The compound 4-hydroxy-2,3-dimethoxy-6-methyl-5-(3,7,11-trimethyl-dodeca-2,6,10-trienyl)-cyclohex-2-enone of the invention is isolated and purified from the extracts of | 01-03-2013 |
20130018105 | CIS, 3,4-DIHYDROXY-2-(3-METHYLBUTANOYL)-5-(3-METHYLBUTYL)-4-(4-METHYLPENTA- NOYL)CYCLOPENT-2-EN-1-ONE DERIVATIVES, SUBSTANTIALLY ENANTIOMERICALLY PURE COMPOSITIONS AND METHODS - The present application provides cis 3,4-dihydroxy-2-(3-methylbutanoyl)-5-(3-methylbutyl)-4-(4-methylpentanoyl)cyclopent-2-en-1-one derivatives and substantially enantiomerically pure compositions thereof. These derivatives include (+)-(4S,5R)—3,4-dihydroxy-2-(3-methylbutanoyl)-5-(3-methylbutyl)-4-(4-methylpentanoyl)cyclopent-2-en-1-one, (−)-(4R,5S)-3,4-dihydroxy-2-(3-methylbutanoyl)-5-(3-methylbutyl)-4-(4-methylpentanoyl)cyclopent-2-en-1-one, and salts and crystals thereof. The application further provides methods of using the disclosed compounds and compositions to activate PPARγ, activate GPR120, inhibit inflammation, and treat conditions responsive to PPARγ modulation, conditions responsive to GPR120 modulation, and metabolic disturbances such as diabetes. | 01-17-2013 |
20130018106 | HOP ACIDS AS A REPLACEMENT FOR ANTIBIOTICS IN ANIMAL FEED - A method of using hop acids for increasing food and energy uptake from feed by livestock is described which includes delivering the hop acids for oral ingestion to the animals by mixing the acids with livestock feed. The acids are mixed with the feed in an amount to inhibit certain types of undesirable bacteria in the livestock's digestive system, thereby increasing the production of propionate and lactate and decreasing the production of methane gas. | 01-17-2013 |
20130053449 | METHOD FOR INHIBITING HISTONE GENE TRANSCRIPTION AND EXPRESSION - A method for inhibiting at least one of histone gene transcription and histone expression in a subject is provided. The method comprises administrating to the subject an effective amount of a compound of formula (I) or a pharmaceutically acceptable salt thereof: | 02-28-2013 |
20130053450 | TREATMENT OF PERVASIVE DEVELOPMENTAL DISORDERS WITH REDOX-ACTIVE THERAPEUTICS - Methods of treating or suppressing pervasive developmental disorders (PDDs) including; autistic disorder, Asperger's syndrome, childhood disintegrative disorder (CDD), Rett's disorder, and PDD-not otherwise specified (PDD-NOS) or attention deficit/hyperactivity disorder (ADHD) comprising administering to a subject in need thereof a therapeutically effective amount of one or more compounds as disclosed herein. | 02-28-2013 |
20130116337 | METHODS AND COMPOSITIONS FOR TREATING CONDITIONS MEDIATED BY OXIDATIVE STRESS OR ELECTROPHILIC ENVIRONMENTAL TOXINS - Methods and compositions are disclosed for treating a subject with a disease or tissue injury mediated by cellular oxidative stress or with an environmental toxicity due to an electrophilic toxicant or pollutant, and for providing a nutritional supplement to a subject and for providing a skin treatment for a subject, where the methods comprise administering to the subject a 1,3-dicarbonyl compound. | 05-09-2013 |
20130131183 | METHODS AND COMPOSITIONS FOR IMPROVING THE HEALTH OF ANIMALS - The invention features compositions and methods for the administration of an oxidatively transformed carotenoid, or a fractionated component thereof, for improving the health of animals, such as increasing joint mobility, increasing activity, and improving coat quality. | 05-23-2013 |
20130137776 | METHOD FOR INHIBITING HISTONE GENE TRANSCRIPTION AND EXPRESSION - A method for inhibiting at least one of histone gene transcription and histone expression in a subject is provided. The method comprises administrating to the subject an effective amount of a compound of formula (I) or a pharmaceutically acceptable salt thereof: | 05-30-2013 |
20130158126 | CANNABINOID QUINONE DERIVATIVES - Cannabinoid quinone derivatives. The present invention refers to cannabinoid quinone derivatives to be used as medicaments, particularly as PPAR gamma (PPARg) agonists for treating diseases which etiology is based on an impaired PPARg function as transcription factor i.e. PPARg-related diseases. | 06-20-2013 |
20130172424 | METHODS AND COMPOSITIONS FOR TREATING DIABETES - The present invention provides methods and compositions for treating diabetes by cyclohexenone compounds. | 07-04-2013 |
20130203861 | METHODS AND COMPOSITIONS FOR TREATING OVARIAN CANCER - The present invention provides methods and compositions for treating ovarian cancer by cyclohexenone compounds. | 08-08-2013 |
20130217781 | CIS 3,4-DIHYDROXY-2-(3-METHYLBUTANOYL)-5-(3-METHYLBUTYL)-4-(4-METHYLPENTAN- OYL)CYCLOPENT-2-EN-1-ONE DERIVATIVES, SUBSTANTIALLY ENANTIOMERICALLY PURE COMPOSITIONS AND METHODS - The present application provides cis 3,4-dihydroxy-2-(3-methylbutanoyl)-5-(3-methylbutyl)-4-(4-methylpentanoyl)cyclopent-2-en-1-one derivatives and substantially enantiomerically pure compositions thereof. These derivatives include (+)-(4S,5R)-3,4-dihydroxy-2-(3-methylbutanoyl)-5-(3-methylbutyl)-4-(4-methylpentanoyl)cyclopent-2-en-1-one, (−)-(4R,5S)-3,4-dihydroxy-2-(3-methylbutanoyl)-5-(3-methylbutyl)-4-(4-methylpentanoyl)cyclopent-2-en-1-one, and salts and crystals thereof. The application further provides methods of using the disclosed compounds and compositions to activate PPARγ, activate GPR120, inhibit inflammation, and treat conditions responsive to PPARγ modulation, conditions responsive to GPR120 modulation, and metabolic disturbances such as diabetes. | 08-22-2013 |
20130225691 | METHODS AND COMPOSITIONS FOR TREATING CANCER METASTASIS - The present invention provides methods and compositions for treating cancer metastasis by cyclohexenone compounds. | 08-29-2013 |
20140031433 | FORMULATIONS OF TOCOTRIENOL QUINONES FOR THE TREATMENT OF OPHTHALMIC DISEASES - A formulation, comprising an ophthalmically effective amount of one or more tocotrienol quinones, particularly of alpha-tocotrienol quinone is disclosed. Use of a formulation comprising one or more tocotrienol quinones for the prevention, reduction, amelioration or treatment of ophthalmic disorders that are associated with a neurodegenerative or trauma disorder is also discussed. A method of treating or controlling the ocular symptoms associated with neurodegenerative diseases or trauma with a formulation comprising one or more tocotrienol quinones is also discussed. A method of treating or controlling the ocular symptoms associated with mitochondrial myopathies with a formulation comprising one or more tocotrienol quinones is also discussed. | 01-30-2014 |
20140039065 | TREATMENT OF LEBER'S HEREDITARY OPTIC NEUROPATHY AND DOMINANT OPTIC ATROPHY WITH TOCOTRIENOL QUINONES - The present invention relates to methods of treating Leber's hereditary optic neuropathy and dominant optic atrophy with tocotrienol quinones, including alpha-tocotrienol quinone, in order to alleviate symptoms of the disease. | 02-06-2014 |
20140066520 | NOVEL ANTI-INFLAMMATORY CYCLOOXYGENASE INHIBITORS - Disclosed is a pharmaceutical composition including a therapeutic quantity of a COX-2 inhibitor having an IC50-WHMA COX-2/COX-1 ratio ranging from about 0.23 to about 3.33 with reduced gastrointestinal and cardiovascular toxicity. Also disclosed are methods for treating osteoarthritis, rheumatoid arthritis or acute pain with less side-effects and faster onset of action utilizing the disclosed pharmaceutical composition. | 03-06-2014 |
20140135402 | CYCLODODECADIENONE DERIVATIVES AS PERFUMING INGREDIENTS - The present invention relates to compounds of Formula (I), wherein one R group is a hydrogen atom and the other is a hydrogen atom or a C | 05-15-2014 |
20140179800 | Inhibition of the Survival of Bladder Cancer by Cyclohexenone Compounds from Antrodia Camphorata - The present invention relates to a novel application of a compound. The compound 4-hydroxy-2,3-dimethoxy-6-methyl-5-(3,7,11-trimethyl-dodeca-2,6,10-trienyl)-cyclohex-2-enone of the invention is isolated and purified from the extracts of | 06-26-2014 |
20140179801 | Inhibition of the Survival of Lymphoma by Cyclohexenone Compounds from Antrodia Camphorata - The present invention relates to a novel application of a compound. The compound 4-hydroxy-2,3 -dimethoxy-6-methyl-5-(3,7,11-trimethyl-dodeca-2,6, 10-trienyl)-cyclohex-2-enone of the invention is isolated and purified from the extracts of | 06-26-2014 |
20140206772 | TREATMENT OF PERVASIVE DEVELOPMENTAL DISORDERS WITH REDOX-ACTIVE THERAPEUTICS - Methods of treating or suppressing pervasive developmental disorders (PDDs) including; autistic disorder, Asperger's syndrome, childhood disintegrative disorder (CDD), Rett's disorder, and PDD—not otherwise specified (PDD-NOS) or attention deficit/hyperactivity disorder (ADHD) comprising administering to a subject in need thereof a therapeutically effective amount of one or more compounds as disclosed herein. | 07-24-2014 |
20140249234 | Compositions and Methods for Restoring the Stratum Corneum and Treating Dermatological Diseases - The present invention provides methods of treating humans and animals with terpenes and terpenoids in order to restore the stratum granulosum and stratum corneum and treat a dermatological disease, such as, for instance atopic dermatitis. More specifically it provides terpenes and terpenoids such as monoterpenoids, sesquiterpenes and norisoprenoids as ingredients that work to restore and thicken the stratum granulosum and stratum corneum and treat a dermatological disease. Terpenes and terpenoid compounds support the cell proliferation, cell differentiation, growth of skin, skin tissue and keratinocytes by upregulating genes for loricrin filaggrin, caspase 14, hornerin and other late cornified envelope components and vascular endothelial growth factor (VEGF) and downregulation of matrix metalloproteinases. Both terpenes and terpenoids may be applied topically or orally at oral or topical concentrations from about 0.6 mg to about 60 mg per kilogram of body weight per day effective to stimulate growth of the skin layer and prevent damage from ultraviolet radiation (UVR). | 09-04-2014 |
20140296348 | OPHTHALMOLOGICAL AQUEOUS COMPOSITION - The present invention provides an aqueous ophthalmic composition having a pH of 7 or more, containing a terpenoid and zinc chloride. According to the present invention, an aqueous ophthalmic composition is provided in which adsorption of the terpenoid to a container can be inhibited, thereby making it possible to inhibit the reduction in the terpenoid content for a long period of time, the aqueous ophthalmic composition having some excellent actions such as an inhibitory action for histamine release, and an inhibitory action for discharges from the eyes. | 10-02-2014 |
20140336269 | METHODS AND COMPOSITIONS FOR CONTROLLING PESTS - The present invention is directed to pest-controlling compositions comprising as active ingredients one or more β-diones, particularly β-diketones and β-triketones, and to the use of these compositions inter alia for preventing, eradicating, destroying, repelling or mitigating harmful, annoying or undesired pests including insects, arachnids, helminths, molluscs, protozoa and viruses. The present invention is further directed to processes of preparing β-diones by de novo synthesis or from natural sources such as volatile oil-bearing plants from families including Alliaceae, Apiaceae, Asteraceae, Cannabinaceae, Lamiaceae, Pteridaceae, Myrtaceae, Myoporaceae, Proteaceae, Rutaceae and Zingiberaceae. | 11-13-2014 |
20140343166 | TREATMENT OF LEIGH SYNDROME AND LEIGH-LIKE SYNDROME WITH TOCOTRIENOL QUINONES - The present invention relates to methods of treating Leigh Syndrome and Leigh-like Syndrome with tocotrienol quinones, including alpha-tocotrienol quinone, in order to alleviate symptoms of the disease. | 11-20-2014 |
20150057363 | TREATMENT OF METHYLMALONIC ACIDURIA, ISOVALERIC ACIDURIA, AND OTHER ORGANIC ACIDURIAS WITH TOCOTRIENOL QUINONES - The present invention relates to methods of treating methylmalonic aciduria and other organic acidurias with tocotrienol quinones, including alpha-tocotrienol quinone, in order to alleviate symptoms of the disease. | 02-26-2015 |
20150057364 | CLEANSER COMPOSITIONS AND METHODS FOR USING THE SAME - The present invention is directed to anti-microbial cleanser compositions comprising linalool, hinokitiol and dipropylene glycol. The present invention further provides methods for using these compositions to maintain eyelid hygiene, to treat an ocular disorder or to clean a skin surface. The cleanser compositions of the present invention can be in the form of a foam, gel or liquid. | 02-26-2015 |
20150080477 | METHODS AND COMPOSITIONS FOR TREATING ARTERIOSCLEROTIC VASCULAR DISEASES - The present invention provides methods and compositions for treating arteriosclerotic vascular diseases by cyclohexenone compounds. In some embodiments, the compound in the methods inhibits PDGF-stimulated smooth muscle cell proliferation or migration. In some embodiments, the atherosclerosis is associated with coronary artery disease, aneurysm, arteriosclerosis, myocardial infarction, embolism, stroke, thrombosis, angina, vascular plaque inflammation, vascular plaque rupture, Kawasaki disease, calcification or inflammation. In some embodiments, the compound lowers low-density lipoprotein (LDL) cholesterol in the subject. In some embodiments, the compound maintains a normal low-density lipoprotein (LDL) cholesterol level in the subject. | 03-19-2015 |
20150087722 | TREATMENT FOR BREAST TUMOR CELL METASTASIS - A method for inhibiting or preventing metastasis of breast tumor cells in a subject is disclosed. The method includes administering to the subject an effective amount of a compound of formula (I). In formula (I), R is H or methyl. | 03-26-2015 |
20150094380 | AGENT FOR IMPROVING VESICOURETHRAL DYSSYNERGIA - This invention is directed to an ameliorating agent for a disease based on vesicourethral dyssynergia, comprising, as an active ingredient, 3-(15-hydroxypentadecyl)-2,4,4-trimethyl-2-cyclohexene-1-one, a salt thereof, or a solvate thereof. The disease based on vesicourethral dyssynergia is any of dysuria accompanying a lifestyle-related disease (such as diabetic dysuria), idiopathic dysuria, dysuria after pelvic surgery, dysuria accompanying spinal cord injury, dysuria accompanying spinal canal stenosis, dysuria accompanying benign prostatic hypertrophy, dysuria accompanying high-pressure voiding/high-pressure urine storage, neurogenic or nonneurogenic lower urinary tract symptoms (LUTS), detrusor sphincter dyssynergia, and detrusor bladder neck dyssynergia. | 04-02-2015 |
20150133565 | SUSTAINED RELEASE HYDROGEL-BASED STIMULANT - The present invention relates to a thermo-responsive hydrogel polymer formulated with one or more active agents selected from the group consisting of menthol and menthone, wherein said active agents are effective in invigorating the user and/or effective in relieving fatigue. | 05-14-2015 |
20150313852 | ANIMAL FEED COMPOSITIONS AND FEEDING METHODS - This invention relates to animal feed compositions. The invention also provides compositions comprising a compound of this invention and the use of such compositions in methods of increasing and optimizing feed efficiency in animals. | 11-05-2015 |
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20160008299 | NEURONAL CIRCUIT-DEPENDENT NEUROPROTECTION BY INTERACTION BETWEEN NICOTINIC RECEPTORS | 01-14-2016 |
20160038441 | METHOD FOR INHIBITING CANCER CELL GROWTH - Disclosed is a method for inhibiting cancer cell growth in a subject in need thereof, comprising administering to the subject an effective amount of a compound from | 02-11-2016 |
20160143862 | METHOD OF USING BETA-IONONE TO TREAT AND PREVENT DISEASE INDUCED BY PROPIONIBACTERIUM ACNES - A method of using beta-ionone, E)-4-(2,6,6-trimethylcyclohex-1-en-1-yl)but-3-en-2-one, treats and prevents diseases otherwise induced by | 05-26-2016 |
20160184239 | METHODS AND COMPOSITIONS FOR TREATING KIDNEY DISORDERS - The present invention provides methods for treating glomerulosclerosis such as focal segmental glomerulosclerosis (FSGS) or glomerulonephritis such as immunoglobulin A nephropathy (IgAN) by cyclohexenone compounds. | 06-30-2016 |
20160185703 | COMPOUNDS FROM ANTRODIA CAMPHORATA, METHOD FOR PREPARING THE SAME AND USE THEREOF - The invention relates to bioactive compounds purified from mycelium of | 06-30-2016 |
20170231925 | METHOD FOR TREATING A NEUROVASCULAR COMPLICATION OF DIABETES MELLITUS | 08-17-2017 |