| Entries |
| Document | Title | Date |
|---|
| 20080319077 | Remedy for Diabetes - The present invention relates to a therapeutic agent for diabetes with sulfonylurea secondary failure, which contains a GPR40 agonist. According to the present invention, a therapeutic agent for diabetes with sulfonylurea secondary failure that affords a superior insulin secretion effect and a superior hypoglycemic effect even in diabetic patients for whom a sulfonylurea compound or a fast-acting insulin secretagogue fails to provide an insulin secretion effect and therefore, fails to provide a sufficient hypoglycemic effect can be provided. | 12-25-2008 |
| 20090036535 | Biphenyloxyacetic Acid Derivatives for the Treatment of Respiratory Disease - The invention relates to substituted phenoxyacetic acids as useful pharmaceutical compounds for treating respiratory disorders, pharmaceutical compositions containing them, and processes for their preparation. | 02-05-2009 |
| 20090036536 | Biphenyl compound selective agonists of gamma RAR receptors - Biphenyl compounds having the formula (I): | 02-05-2009 |
| 20090042990 | NOVEL USE OF A NUTRACEUTICAL COMPOSITIONS IN ANIMAL FEED - This invention relates to the novel use of a composition comprising benzoic acid or a derivative of benzoic. It has been found surprisingly that the long-term ingestion of benzoic acid by swine was followed by a significant increase of the bone resistance and mineralization. The benzoic acid or its derivative can be administered to the animal either in its feed composition or in its drinking water. | 02-12-2009 |
| 20090093544 | INSECTICIDAL COMPOSITIONS HAVING IMPROVED EFFECT - The present invention relates to the increase of the action of crop protection agents containing certain phthalic acid diamides by the addition of ammonium salts and/or phosphonium salts or by the addition of ammonium or phosphonium salts and penetration promoters, the corresponding agents, processes for their preparation and their use in crop protection. | 04-09-2009 |
| 20090093545 | PHENOXYALKYCARBOXYLIC ACID DERIVATIVES IN THE TREATMENT OF IRRITABLE BOWEL SYNDROME OR ULCERATIVE COLITIS - A method of treating irritable bowel syndrome, ulcerative colitis, and other inflammatory conditions, comprising: administering to a patient in need thereof an effective amount of a compound selected from compound 1, its metabolite 2 and pharmaceutically acceptable salts or prodrugs thereof: | 04-09-2009 |
| 20090093546 | Method and Pharmaceutical Compositions for Treatment of Anti-Estrogen Resistant Breast Cancer Using RXR Modulators - Methods and compositions for the treatment of anti-estrogen resistant breast cancer using retinoid compounds that are modulators of Retinoid X Receptors are provide. | 04-09-2009 |
| 20090137678 | HIGH YIELD SYNTHESIS METHODS FOR PRODUCING ORGANIC SALTS OF STRONTIUM - New organic salts of strontium and methods of synthesizing such salts with high purity, high yields and with short processing times, at neutral conditions and at low reaction temperature, such as a temperature at or below 50° C. | 05-28-2009 |
| 20090186942 | NOVEL NUTRACEUTICAL AND PHARMACEUTICAL COMPOSITIONS AND USE THEREOF FOR THE TREATMENT, CO-TREATMENT OR PREVENTION OF INFLAMMATORY DISORDERS - The invention relates to novel compositions comprising a phenolic compound as well as to the use of these compositions as a medicament, in particular for the manufacture of a nutraceutical or pharmaceutical composition for the treatment, co-treatment or prevention of inflammatory disorders, such as arthritis, asthma, inflammatory bowel diseases, inflammatory diseases of the skin (e.g., psoriasis, eczema, atopic dermatitis, sunburn) and chronic inflammatory disorders, such as atherosclerosis, heart diseases, metabolic syndrome X, cancer, Alzheimer's disease and pre-stages thereof such as mild cognitive impairment. Also, the invention relates to the use of a cosmetic composition comprising a phenolic compound for the cosmetic treatment, co-treatment or prevention of inflammation of the skin, in particular for the cosmetic treatment, co-treatment or prevention of sunburn or of impure skin. | 07-23-2009 |
| 20090264530 | COMBINED NSAID AND ACETAMINOPHEN FORMULATION AND METHOD - The present invention is directed to co-administration of a non-steroidal anti-inflammatory agent (NSAID) and acetaminophen for the treatment of pain and inflammation with reduced gastrointestinal irritation. A pharmaceutical composition suitable for the co-administration contains a therapeutically effective amount of at least one non-steroidal anti-inflammatory agent, and a therapeutically effective amount of acetaminophen or a pharmaceutically acceptable salt thereof. A ratio of the non-steroidal anti-inflammatory agent to acetaminophen in the composition is within a range that provides greater pain relief and reduction of inflammation with less gastrointestinal irritation than that obtainable by the administration of the non-steroidal anti-inflammatory agent or acetaminophen alone. Examples of pharmaceutical compositions for co-administration of the agents are those containing ibuprofen in combination with the acetaminophen. | 10-22-2009 |
| 20090275661 | PREPARATION OF THE FORMAURINDICARBOXYLIC ACID BASE AND ITS DERIVATIONS AND USE - A pharmaceutical composition comprising at least 0.1 μmol of formaurindicarboxylic acid or its derivatives in 1 kg of pharmaceutically acceptable carrier. The pharmaceutical composition of claim | 11-05-2009 |
| 20090306210 | Solubilizates of Preservatives and Method for Producing the Same - Described is a solubilisate of a preservative containing an aliphatic and/or aromatic acid such as sorbic acid and/or benzoic acid that is free of stabilizing agents, as well as one or more emulsifiers with an HLB value between 9 and 18 with a concentration of about 50% and about 95% emulsifier with regard to the total quantity of the solubilisate, and a procedure for the production of such a solubilisate. | 12-10-2009 |
| 20100010089 | SYSTEM AND METHOD FOR PRODUCTION AND USE OF FULVIC ACID - A method and system for producing fulvic acid and humic acid comprises extracting a liquid from an organic compost mixture. The liquid may be extracted by collecting liquid that percolates from the organic compost mixture or by separating liquid from solid components in the organic compost mixture. The extracted product comprises fulvic acid in an amount of at least 4% by weight, and more specifically at least 7%, and humic acid in an amount less than approximately 3% by weight. | 01-14-2010 |
| 20100010090 | AMPA RECEPTOR POTENTIATORS - The present invention relates to a compound of Formula (I) or a pharmaceutically acceptable salt thereof which is useful for the treatment of conditions associated with glutamate hypofunction, such as psychiatric and neurological disorders. | 01-14-2010 |
| 20100029772 | Dicarboxylic Acid Derivatives and their Use - The present application relates to novel dicarboxylic acid derivatives, process for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for producing medicaments for the treatment and/or prophylaxis of diseases, especially for the treatment and/or prevention of cardiovascular disorders. | 02-04-2010 |
| 20100041757 | N-ARYL-HYDROXYALKYLIDENE-CARBOXAMIDE COMPOUNDS AND THEIR USE - This disclosure generally relates to chemicals that affect sensory processes. More particularly, this present invention relates to peripheral sensory compounds (including, e.g., 2-Isopropyl-5-methyl-cyclohexanecarboxylic acid [2′-hydroxy-2′-(3″-hydroxy-phenyl)-ethyl]-N-methyl-amide) that are useful in sensory refreshment, inhibit the perception of itch and pain, and alleviation of skin irritation, itch, and pain. These compositions have surprising pharmacokinetic properties that allow a prolonged duration of pharmacological actions and may be administered topically or systemically. | 02-18-2010 |
| 20100063153 | ANTI-CHOLESTEROLEMIC COMPOUNDS AND METHODS OF USE - The present invention provides novel compounds with hypocholesteremic activity from crude | 03-11-2010 |
| 20100087538 | DRUG SUBSTANCE PREPARATIONS, PHARMACEUTICAL COMPOSITIONS AND DOSAGE FORMS - The invention relates to drug substance preparations, pharmaceutical compositions and dosage forms containing (R)-(−)-2-(2-fluoro-4-biphenylyl) propionic acid as the active pharmaceutical ingredient, and limited amounts of specific product-related and process-related impurities. | 04-08-2010 |
| 20100120919 | METHODS FOR TREATING TRANSTHYRETIN AMYLOID DISEASES - Kinetic stabilization of the native state of transthyretin is an effective mechanism for preventing protein misfolding. Because transthyretin misfolding plays an important role in transthyretin amyloid diseases, inhibiting such misfolding can be used as an effective treatment or prophylaxis for such diseases. Treatment methods are disclosed. | 05-13-2010 |
| 20100160438 | NOVEL USE OF A NUTRACEUTICAL COMPOSITION IN ANIMAL FEED - This invention relates to a composition comprising benzoic acid or a derivative of benzoic. It has been found surprisingly that benzoic acid and salts thereof have the advantage of being able to improve digestibility of proteins in animal feeds, i.e. to promote amino acid and nitrogen assimilation, and to increase total energy levels. Moreover, it has been found that benzoic acid improves the digestibility of animal feed containing maize-soybean meal as a major part of the feed diet. The benzoic acid or its derivative can be administered to the animal either in its feed composition or in its drinking water. It is particularly effective in pigs. | 06-24-2010 |
| 20100168240 | SUBSTITUTED DIBENZOIC ACID DERIVATIVES AND USE THEREOF - The invention relates to novel substituted dibenzoic acid derivatives of formula (I), wherein A represents a group of formula (II) or (III), to methods for producing the same, and to their use in the treatment and/or prophylaxis of diseases. The invention also relates to the use of said substances in the production of drugs for the treatment and/or prophylaxis of diseases, especially in the treatment and/or prevention of cardiovascular diseases. | 07-01-2010 |
| 20100216888 | LIQUID COMPOSITIONS CONTAINING SOLUBILIZED BENZOYL PEROXIDE, MEANS FOR APPLYING SAME AND METHODS OF TREATMENT USING SAME - Liquid medicaments incorporate about 1.0-3.0% active benzoyl peroxide (BP) by weight in substantially fully solubilized form, while being substantially free of acetone and other harsh, dermatologically undesirable solvents. The novel compositions are produced by (a) creating an emulsion or slurry of BP in an emollient, topically acceptable ester, and (b) dissolving the emulsion or slurry in absolute alcohol. The medicaments may be used in the treatment of BP-responsive skin conditions in mammals, e.g., acne vulgaris or rosacea. The novel medicaments may be dispensed directly to the affected skin area through the use of an applicator device comprising a fluid reservoir associated with a foam applicator tip, or via a spray dispenser, atomizer or pump spray. | 08-26-2010 |
| 20100261795 | Antiacneic compositions - The invention relates to novel powerful and non-irritating formulations of antiacneic substances and polyolprepolymers. The invention further relates to novel formulations of polyolprepolymers in combination with, for example, benzoyl peroxide exhibit progressive release of the active with a decrease in irritating effects. These formulations may be therapeutically beneficial over existing acne therapies. | 10-14-2010 |
| 20100292333 | COMPOSITIONS SUITABLE FOR THE TOPICAL TREATMENT OF FUNGAL INFECTIONS OF THE SKIN AND NAILS - The present invention relates to pharmaceutical compositions suitable for the topical treatment of fungal infections of the skin and nails, such as tinea pedia and tinea cruris, among others. The active ingredients of the present compositions are low molecular weight organic acids and their salts, many of which are previously known as antifungal agents to some degree but which, when used in combination, produce a synergistic enhancement in antifungal potency such that the combined effect is greater than that when used by the agents alone. The antifungal activity of the active ingredients is further enhanced through the use of non-volatile hygroscopic solvents rather than the aqueous or volatile organic solvents used in the art. | 11-18-2010 |
| 20110009490 | PREPARATION OF THE FORMAURINDIKARBOXYL ACID BASE AND ITS DERIVATIONS AND USE - A pharmaceutical composition comprising at least 0.1 μmol of formaurindicarboxylic acid or its derivatives in 1 kg of pharmaceutically acceptable carrier. The pharmaceutical composition of claim | 01-13-2011 |
| 20110046223 | TREATMENT OF NEUROFIBROMATOSIS - Disclosed are methods of treating neurofibromatosis by administering to a human in need thereof effective amounts of FTS, or various analogs thereof, or a pharmaceutically acceptable salt thereof, optionally, in combination with colchicine. Also disclosed are pharmaceutical compositions comprising FTS, or various analogs thereof, or a pharmaceutically acceptable salt thereof; colchicine; and a pharmaceutically acceptable carrier. | 02-24-2011 |
| 20110046224 | METHODS TO ACCELERATE MUSCLE DEVELOPMENT, DECREASE FAT DEPOSITS, AND ENHANCE FEEDING EFFICIENCY IN PIGS - A natural method to promote or enhance food efficiency and muscle/fat ratio in animals is described, particularly for pigs, through the administration of an effective amount of pure ferulic acid, substantially pure ferulic acid or ferulic acid formulations. Prepared food and formulations for animals are also described, which can increase muscular development in pigs, decreasing fat deposits or promoting or increasing animal growth or enhancing food efficiency in an animal. Effective amounts of pure ferulic acid or substantially pure ferulic acid use in said food preparations and formulations are described. | 02-24-2011 |
| 20110060047 | APPROACHES TO TREAT CANCER USING HB-EGF INHIBITORS - The invention provides methods for the treatment of cancer in a subject by the administration of myrsinoic acid A and/or one or more myrsinoic acid A analogs. | 03-10-2011 |
| 20110112195 | Potent and Selective Inhibition by Aurinticarboxylic Acid - The severe acute respiratory syndrome virus (SARS) is a coronavirus that instigated regional epidemics in Canada and several Asian countries in 2003. The newly identified SARS coronavirus (SARS-CoV) can be transmitted among humans and cause severe or even fatal illnesses. As preventive vaccine development takes years to complete and adverse reactions have been reported to some veterinary coronaviral vaccines, anti-viral compounds must be relentlessly pursued. In this study, we analyzed the effect of aurintricarboxylic acid (ATA) on SARS-CoV replication in cell culture, and found that ATA could drastically inhibit SARS-CoV replication, with viral production being more than 1000 fold than that in the untreated control. ATA is also shown to be an effective anti-viral for several other viruses, including West Nile Virus and variola virus. | 05-12-2011 |
| 20110118354 | CYCLOHEXENYL MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY - The present application describes modulators of MCP-1 or CCR-2 of formula, (I) or stereoisomers or prodrugs or pharmaceutically acceptable salts thereof, wherein T, W, X, Y, Z, R | 05-19-2011 |
| 20110144207 | ARYL ALKYL CARBOXYLIC ACID SALTS, PROCESS FOR PREPARATION AND DOSAGE FORMS - The invention particularly discloses a process for preparing aryl alkyl carboxylic acid salts by preparing aqueous alkali solution, adding aryl alkyl carboxylic acid to said alkali solution at a temperature ranging from 4° to 121° C. for obtaining a clear solution, preferably by heating and/or stirring and concentrating and cooling to obtain aryl alkyl carboxylic acid salt The invention therefore discloses solid oral dosage forms and compositions of aryl alkyl carboxylic acid salts which are free of organic solvent/so. The solid oral dose compositions of aryl alkyl carboxylic acid salts of the invention are prepared in situ from aryl alkyl carboxylic acids and bases to obtain aryl acid alkyl carboxylic acid sails in crystalline/powder form with or without the use of pharmaceutical excipients. | 06-16-2011 |
| 20110218248 | ORGANIC COMPOUNDS - The present invention relates to salts, polymorphs and hydrates of 2-Amino-2-[2-(4-C | 09-08-2011 |
| 20110224300 | USE OF POTASSIUM 2-(a- HYDROXYPENTYL) BENZOATE IN THE MANUFACTURE OF MEDICAMENTS FOR PREVENTING AND/OR TREATING SENILE DEMENTIA - The present invention discloses the use of potassium 2-(α-hydroxypentyl) benzoate in the manufacture of medicaments for preventing, relieving or treating senile dementia diseases or symptom, and for relieving oxidative stress injury in brain tissue, increasing neural function of choline, protecting neuron and/or raising the content of brain nerve growth factor. The present invention also discloses a pharmaceutical composition comprising potassium 2-(α-hydroxypentyl) benzoate in prophylactically or therapeutically effective dose, optionally, a pharmaceutically acceptable carrier and/or adjuvant. | 09-15-2011 |
| 20110230560 | SYNERGETIC COMPOSITION COMPRISING FLAVOURING SUBSTANCES AND ORGANIC ACIDS AND USE THEREOF - The present invention relates to a composition comprising a synergetic mixture of flavourings or flavouring substances and organic acids. Moreover, the present invention relates to the use of said composition as a preservative for animal foodstuffs and additives intended preferably for monogastric animals. | 09-22-2011 |
| 20120059062 | COMPOSITIONS COMPRISING CANNABINOIDS FOR TREATMENT OF NAUSEA, VOMITING, EMESIS, MOTION SICKNESS OR LIKE CONDITIONS - Cannabinoids, in particular CBD and CBDA and their acid derivatives are provided for use as an active pharmaceutical substance in the treatment of nausea, vomiting, emesis, motion sickness. In particular extracts of | 03-08-2012 |
| 20120329874 | SYNERGETIC COMPOSITION COMPRISING FLAVOURING SUBSTANCES AND ORGANIC ACIDS AND USE THEREOF - The present invention relates to a composition comprising a synergetic mixture of flavourings or flavouring substances and organic acids. Moreover, the present invention relates to the use of said composition as a preservative for animal foodstuffs and additives intended preferably for monogastric animals. | 12-27-2012 |
| 20130012588 | COMPOSITIONS AND METHODS FOR PREVENTION AND TREATEMENT OF WOUNDS - The present invention provides compositions and methods for promoting rapid healing and/or regeneration of damaged tissue resulting from a wound comprising administering to a subject in need thereof a therapeutically effective amount of a pharmaceutical composition comprising a compound of (E)-4-carboxystyryl-4-chlorobenzylsulfone, or a functional derivative thereof, and a pharmaceutically acceptable excipient. | 01-10-2013 |
| 20130012589 | STABLE AQUEOUS FORMULATION OF (E)-4-CARBOXYSTYRYL-4-CHLOROBENZYL SULFONE - An aqueous pharmaceutical solution composition comprising between about 20 mg/ml to about 100 mg/ml of a radioprotective α,β-unsaturated aryl sulfone, a cosolvent comprising polyethylene glycol (PEG), polypropylene glycol, polyglycerol, DMA, propylene glycol, glycerol, ethanol, sorbitol, isopropyl alcohol, or a combination thereof in an amount between about 25% and about 90% w/v, and a water soluble Vitamin E derivative, wherein the composition has a pH within the range of about 7.0 to about 9.5. | 01-10-2013 |
| 20130116326 | TREATMENT OF DELAYED CUTANEOUS HYPERSENSITIVITY CONDITIONS WITH S-FARNESYLTHIOSALICYLIC ACID AND ANALOGS THEREOF - Disclosed are methods of treating a mammalian subject afflicted with a delayed cutaneous hypersensitivity condition, comprising administering to the subject a pharmaceutical composition comprising an effective amount of S-farnesylthiosalicylic acid (FTS) or a structural analog thereof, and compositions for use in the methods. | 05-09-2013 |
| 20130123365 | USE OF FTS AND ANALOGS TO TREAT NON-AUTOIMMUNE-ALLERGIC AND NON-ALLERGIC INFLAMMATORY CONDITIONS - Disclosed are methods of treating a mammalian subject afflicted with a non-autoimmune inflammatory condition, comprising administering to the subject a pharmaceutical composition comprising an effective amount of S-farnesylthiosalicylic acid (FTS) or a structural analog thereof, and compositions useful in the practice of the methods. | 05-16-2013 |
| 20130274339 | NOVEL FUNCTIONAL FOOD PRODUCT AND METHOD THEREOF - A whole impregnated freeze dried food product for delivering a material of interest comprising;
| 10-17-2013 |
| 20130296432 | BENZOIC ACID-ENRICHED PLANT EXTRACTS AND USE THEREOF - Disclosed herein are benzoic acid-enriched plant extracts and uses thereof Specifically, benzoic acid-enriched plant extracts free of toxic substances and organic solvents and use thereof are disclosed. More specifically, a benzoic acid-enriched lingonberry extract free of toxic substances and organic solvents and its use as a preservative is provided. | 11-07-2013 |
| 20130303619 | Antibacterial Compositions - The present invention relates to oral antibacterial compositions comprising trihydroxybenzoate derivatives, e.g., useful for the treatment of gum diseases (e.g., gingivitis or periodontitis) and to methods of using such compositions. | 11-14-2013 |
| 20130331452 | BENZOIC ACID COMPOUNDS FOR REDUCING URIC ACID - Uric acid in mammalian subjects is reduced and excretion of uric acid is increased by administering a compound of Formula (I). The uric acid-lowering effects of the compounds of this invention are used to treat or prevent a variety of conditions including gout, hyperuricemia, elevated levels of uric acid that do not meet the levels customarily justifying a diagnosis of hyperuricemia, renal dysfunction, kidney stones, cardiovascular disease, risk for developing cardiovascular disease, tumor-lysis syndrome, cognitive impairment, early-onset essential hypertension, and | 12-12-2013 |
| 20140100286 | COMPOSITION FOR PREVENTING OR TREATING INFLAMMATORY DISEASES COMPRISING VERATRIC ACID AS EFFECTIVE COMPONENT - There is provided a composition including a veratric acid for preventing or treating inflammatory diseases. The veratric acid of the present invention has an excellent effect of inhibiting production of nitric oxide, an excellent activity of inhibiting production of IL-1β as a pro-inflammatory cytokine, and an excellent effect of inhibiting phosphorylation of MAPK, NF-κB, GSK-3β, and c-Raf in a macrophage cell stimulated by a stimulation factor that causes an inflammatory reaction. Thus, it can be used for development of medicines for treating inflammatory diseases which can be caused by excessive inflammatory reactions. Further, the veratric acid of the present invention does not induce toxicity to cells and is stable in the body. Thus, it can be used as a material of a health functional food capable of preventing or improving inflammatory diseases. | 04-10-2014 |
| 20140135398 | Antioxidant Producing Bacterium and Uses Thereof - Bacterial strains are provided that can be isolated from the microflora of lowbush blueberry ( | 05-15-2014 |
| 20140163106 | Protection against skin diseases by aurin tricarboxylic acid and its derivatives - This invention describes a method of preventing and treating inflammatory skin diseases by topical application of aurin tricarboxylic acid and its derivatives. Such diseases are characterized by immune attack, especially involving aberrant complement activation. The diseases include, but are not limited to, androgenetic alopecia (baldness), seborrheic dermatitis/dandruff, allergic dermatitis, primary cicatricial alopecia, pemphigus, psoriasis, discoid lupus erythematosis and dermatitus herpetiformis. | 06-12-2014 |
| 20140235722 | Organic Compounds - The present invention relates to salts, polymorphs and hydrates of 2-Amino-2-[2-(4-C | 08-21-2014 |
| 20140296339 | SUBSTITUTED PHENETHYLAMINES WITH SEROTONINERGIC AND/OR NOREPINEPHRINERGIC ACTIVITY - Chemical syntheses and medical uses of novel inhibitors of the uptake of monoamine neurotransmitters and pharmaceutically acceptable salts and prodrugs thereof, for the treatment and/or management of psychotropic disorders, anxiety disorder, generalized anxiety disorder, depression, post-traumatic stress disorder, obsessive-compulsive disorder, panic disorder, hot flashes, senile dementia, migraine, hepatopulmonary syndrome, chronic pain, nociceptive pain, neuropathic pain, painful diabetic retinopathy, bipolar depression, obstructive sleep apnea, psychiatric disorders, premenstrual dysphoric disorder, social phobia, social anxiety disorder, urinary incontinence, anorexia, bulimia nervosa, obesity, ischemia, head injury, calcium overload in brain cells, drug dependence, and/or premature ejaculation are described. | 10-02-2014 |
| 20140336257 | ADMINISTRATION OF ADAPALENE AND BENZOYL PEROXIDE FOR THE LONG-TERM TREATMENT OF ACNE VULGARIS - A regimen for the safe and effective long-term treatment of acne vulgaris entails topically applying onto the affected skin area of a subject afflicted therewith, for a period of time of at least four (4) months, e.g., for at least twelve (12) months and advantageously on a daily basis and preferably once a day, a thus effective amount of a topical medicament containing adapalene and benzoyl peroxide, formulated into a pharmaceutically acceptable medium therefor. | 11-13-2014 |
| 20140336258 | ANTI-VIRULENCE COMPOSITIONS AND METHODS - A method of reducing the virulence of a bacterium that expresses accessory gene regulator A (AgrA) includes administering to the bacterium an amount of AgrA antagonist effective to inhibit the synthesis of one or more virulence factors by the bacterium. | 11-13-2014 |
| 20140343155 | ANTIMICROBIAL COMPOSITION - The present invention relates to a method of disinfecting a surface and to an antimicrobial composition. Essential oils, which are used as antimicrobial actives, are also known for their strong odour; using high amounts of these gives a strong smell to the product that is not always appreciated by the consumer. It is therefore an object of the invention to provide an antimicrobial composition, having good anti-microbial properties, at very low levels of essential oil actives. The present inventors have achieved this using a synergistic combination of select anti-microbial actives and select hydrotropes. | 11-20-2014 |
| 20150065573 | TREATMENT OF AGE-RELATED MACULAR DEGENERATION - A method of treating age-related macular degeneration. The method includes the step of administering orally or parenterally an effective amount of aurin tricarboxylic acid, aurin quadracarboxylic acid, and/or aurin hexacarboxylic acid, wherein the method excludes administration of components of aurin tricarboxylic acid complex of greater than or equal to 1 kilodalton in molecular weight. | 03-05-2015 |
| 20150065574 | TREATMENT OF ATYPICAL HEMOLYTIC UREMIC SYNDROME - A method of treating atypical hemolytic uremic syndrome. The method includes the step of administering orally or parenterally an effective amount of aurin tricarboxylic acid, aurin quadracarboxylic acid, and/or aurin hexacarboxylic acid, wherein the method excludes administration of components of aurin tricarboxylic acid complex of greater than or equal to 1 kilodalton in molecular weight. | 03-05-2015 |
| 20150290155 | METHODS AND KITS FOR PREVENTION AND TREATMENT OF CANCER - A method of preventing and/or treating cancer in a subject is provided. The method includes administering to the subject a composition comprising an effective amount of an active agent selected from the group consisting of aurin tricarboxylic acid (ATA), aurin quadracarboxylic acid (AQA), aurin hexacarboxylic acid (AHA), aurin tricarboxylic acid complex (ATAC), and pharmaceutically acceptable salts thereof. The method excludes administration of components of crude aurin tricarboxylic acid greater than or equal to 1 kilodalton in molecular weight. | 10-15-2015 |
| 20160015765 | Plant Extracts Having Anticoccidial Activity - Natural plant parts and extracts of plants selected from the group consisting of | 01-21-2016 |
| 20160101076 | Use of Sumoylation Inhibitors for Treating Cancer - The present invention provides methods and reagents for treating cancer cells for therapeutic purposes, by contacting with a sumoylation inhibitor in a dose effective to block sumoylation of TFAP2A. In breast cancer cells the sumoylation inhibitor induces a basal to luminal shift in phenotype. Sumoylation inhibitors also reduce the number of cancer stem cells in a cancer cell population. Inhibition of sumoylation makes cancer cells more responsive to conventional chemotherapeutic therapy and radiation therapy and decreases recurrence or development of metastases. | 04-14-2016 |
| 20160157484 | NATURAL ANTIMICROBIAL COMPOSITIONS - The present invention provides novel antimicrobial compositions. In one embodiment, the antimicrobial composition comprises an antimicrobial effective amount of a mixture comprising (a) two or more fatty acids, each of which is natural or naturally derived, and (b) at least one of (i) a natural or naturally derived product, (ii) an alcoholic solvent, or (iii) an organic acid or a salt thereof. The present invention also provides a product comprising a preservative effective amount of the aforementioned mixture. | 06-09-2016 |
| 20170231221 | Methods, Compounds and Compositions for Repelling Insects and/or Arachnids | 08-17-2017 |
| 20180021277 | ANTI-VIRULENCE COMPOSITIONS AND METHODS | 01-25-2018 |
| 20220133678 | METHOD FOR TREATMENT OF ROSACEA - A regimen is described for the therapeutic treatment of rosacea. The regimen includes topically applying a pharmaceutical composition to the skin of a subject in need of said treatment. The pharmaceutical composition includes from about 2.5% to about 10% benzoyl peroxide as the only active ingredient, and a pharmaceutically acceptable carrier or excipient. The regimen achieves, in a group of such subjects, a primary measure of success of at least about 9%, at least about 25%, at least about 40%, or at least about 47%, after application of said pharmaceutical composition once daily for at least about 2 weeks, at least about 4 weeks, at least about 8 weeks, or at least about 12 weeks, respectively. | 05-05-2022 |
