| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 514521000 | C=O other than as ketone or aldehyde | 84 |
| 20080227858 | Inhibitors of matrix metalloproteinase - Compounds of formula (I): | 09-18-2008 |
| 20090111873 | Novel Zeta-Cypermethrin Composition - The present invention is directed to an insecticidal composition comprising zeta-cypermethrin: a) prepared by an epimerization process, and b) containing a residual amount of an epimerization catalyst, and glycerine, wherein the zeta-cypermethrin is present in an insecticidally effective amount and to methods of using the composition. | 04-30-2009 |
| 20090131518 | Insecticidal and Miticidal Mixtures of Bifenthrin and Cyano-Pyrethroids - The present invention is directed to novel insecticidal and/or miticidal compositions comprising bifenthrin and a cyano-pyrethroid. The compositions exhibit an unexpected increase in insecticidal activity as compared to the insecticidal activity of the individual components. | 05-21-2009 |
| 20090143465 | ESTER COMPOUND AND ITS USE IN PEST CONTROL - An ester compound represented by the formula (I): | 06-04-2009 |
| 20090170935 | Novel Formulations of Bifenthrin and Enriched Cypermethrin - The present invention is directed to novel insecticidal compositions comprising bifenthrin and enriched cypermethrin, the compositions are physically stable when diluted with water. | 07-02-2009 |
| 20090170936 | Ester Compound and Its Use - An ester compound represented by the formula (1): | 07-02-2009 |
| 20090326062 | PROCESS FOR PREPARING ENTACAPONE SUBSTANTIALLY FREE OF Z-ISOMER, SYNTHESIS INTERMEDIATES THEREOF AND A NEW CRYSTALLINE FORM - The present invention relates to a new method for obtaining Entacapone substantially free of Z-isomer from 3,4-dihydroxy-5-Nitrobenzaldehyde and N,N-Dimethylcyanoacetamide, or directly from a mixture of (E)- and (Z)-isomers of Entacapone, by formation of organic or inorganic salts, specially piperidine and sodium ones. A new crystalline form G of Entacapone can be obtained from this method in a fast, efficient, and simple way and substantially free of Z-isomer. Another object of the invention is a pharmaceutical composition comprising it. | 12-31-2009 |
| 20100048700 | LIQUID FORMULATION OF PYRETHROIDS - New agrochemical formulations have been found, comprising
| 02-25-2010 |
| 20100190851 | Use of Entacapone in cosmetic, dermatological and pharmaceutical compositions - A compound of formula (I), a salt of this compound or an isomeric or polymorphic form thereof can be used for the preparation of a cosmetic or dermatological composition, which is useful for the treatment or prophylaxis of itching or skin ageing caused by a combination of intrinsic and extrinsic factors. | 07-29-2010 |
| 20100190852 | SHORT ACTING PHENYLALKYLAMINE CALCIUM CHANNEL BLOCKERS AND USES THEREOF - The present invention relates to the use of a pharmaceutically effective amount of an short-acting calcium channel blocking compound to treat ischemic heart conditions, cardiac arrhythmias, hypertensive crisis in an emergency room setting, hypertension before, during, or after surgery, no-reflow phenomenon following reperfusion, and diseases associated with decreased skeletal muscle blood flow. The invention also relates to pharmaceutical compositions formulated for use in such methods and to kits for such methods. | 07-29-2010 |
| 20100286265 | ALPHA-CYANO-4-FLUORO-3-PHENOXYBENZYL META-HALO PYRETHRATE, A PROCESS FOR PREPARING THE SAME AND THE USES THEREOF - The present invention relates to a compound of formula (I), stereoisomers thereof or the mixture of these stereoisomers, wherein: X represents a halogen atom, i.e. F, Cl, Br. The present invention also relates to a process for preparing the compound, and to a use of the compound in the preparation of an insecticide for controlling or killing vectors in the public hygiene and disease control, and to a use of the compound in the preparation of an insecticide for controlling or killing insects, nematodes, and mites in agriculture or horticulture. | 11-11-2010 |
| 20100292323 | Aqueous Microemulsions Containing Pyrethroid Compounds - The present invention relates to new aqueous microemulsions containing organic pesticide compounds of limited water-solubility and to their use for plant protection, including seed and crop protection, and protection or non-living material. The aqueous microemulsions comprise a) at least one pyrethroid compound P; b) at least one organic solvent, selected from compounds of the formula I R | 11-18-2010 |
| 20100298428 | Continuous Administration of Dopa Decarboxylase Inhibitors and Compositions for Same - Disclosed herein are compositions that include for example the arginine salt of carbidopa, and methods for treating neurological or movement diseases or disorders such as restless leg syndrome, Parkinson's disease, secondary parkinsonism, Huntington's disease, Parkinson's like syndrome, PSP, MSA, ALS, Shy-Drager syndrome and conditions resulting from brain injury including carbon monoxide or manganese intoxication, using substantially continuous administration of carbidopa or salt thereof together with administration of levodopa. | 11-25-2010 |
| 20100298429 | Continuous Administration of Dopa Decarboxylase Inhibitors and Compositions for Same - Disclosed herein are compositions that include for example the arginine salt of carbidopa, and methods for treating neurological or movement diseases or disorders such as restless leg syndrome, Parkinson's disease, secondary parkinsonism, Huntington's disease, Parkinson's like syndrome, PSP, MSA, ALS, Shy-Drager syndrome and conditions resulting from brain injury including carbon monoxide or manganese intoxication, using substantially continuous administration of carbidopa or salt thereof together with administration of levodopa. | 11-25-2010 |
| 20100331406 | 4-((PHENOXYALKYL)THIO)-PHENOXYACETIC ACIDS AND ANALOGS - The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR modulators to treat or inhibit the progression of, for example, dyslipidemia. | 12-30-2010 |
| 20110065789 | Ester Compound and Use Thereof - An ester compound represented by the formula (1): | 03-17-2011 |
| 20110269833 | Continuous Administration of Dopa Decarboxylase Inhibitors and Compositions for Same - Disclosed herein are compositions that include for example the arginine salt of carbidopa, and methods for treating neurological or movement diseases or disorders such as restless leg syndrome, Parkinson's disease, secondary parkinsonism, Huntington's disease, Parkinson's like syndrome, PSP, MSA, ALS, Shy-Drager syndrome and conditions resulting from brain injury including carbon monoxide or manganese intoxication, using substantially continuous administration of carbidopa or salt thereof together with administration of levodopa. | 11-03-2011 |
| 20110275710 | Agricultural Pesticide Formulations and Process for Making the Same - The present invention provides an agricultural pesticide formulation of reduced toxicity and high dispersibility, and a process for making the same. | 11-10-2011 |
| 20120172427 | (Z)-2-CYANO-3-HYDROXY-BUT-2-ENOIC ACID-(4'-TRIFLUOROMETHYLPHENYL)-AMIDE TABLET FORMULATIONS WITH IMPROVED STABILITY - The invention relates to solid pharmaceutical compositions comprising (Z)-2-cyano-3-hydroxy-but-2-enoic acid-(4′-trifluoromethylphenyl)-amide, as well as a process for the preparation of the same, methods of using such compositions to treat subjects suffering from autoimmune diseases in particular systemic lupus erythematosus or chronic graft-versus-host disease, multiple sclerosis or rheumatoid arthritis. | 07-05-2012 |
| 20120172428 | Novel Formulations of Bifenthrin and Enriched Cypermethrin - The present invention is directed to novel insecticidal compositions comprising bifenthrin and enriched cypermethrin, the compositions are physically stable when diluted with water. | 07-05-2012 |
| 20120208880 | (Z)-2-CYANO-3-HYDROXY-BUT-2-ENOIC ACID-(4'-TRIFLUORMETHYLPHENYL)-AMIDE TABLET FORMULATIONS WITH IMPROVED STABILITY - The invention relates to solid pharmaceutical compositions comprising (Z)-2-cyano-3-hydroxy-but-2-enoic acid-(4′-trifluoromethylphenyl)-amide, as well as a process for the preparation of the same, methods of using such compositions to treat subjects suffering from autoimmune diseases in particular systemic lupus erythematosus or chronic graft-versus-host disease, multiple sclerosis or rheumatoid arthritis. | 08-16-2012 |
| 20120289594 | ORAL DOSAGE FORM - An oral dosage form of entacapone and methods for the preparation thereof are provided. | 11-15-2012 |
| 20120322870 | ESTER COMPOUND AND USE THEREOF - An ester compound represented by formula (1):
| 12-20-2012 |
| 20130005802 | TREATMENT OF WNT/FRIZZLED-RELATED DISEASES - Methods of treating Wnt/Frizzled-related diseases, comprising administering niclosamide compounds are provided. Methods of predicting whether a disease will respond to treatment with a niclosamide compound are also provided. | 01-03-2013 |
| 20130005803 | USE OF COMPOUNDS IN THE TREATMENT OR PREVENTION OF SKIN DISORDERS - The use of compounds in the treatment of skin disorders is described. In particular, the use of a compound of formula (I) | 01-03-2013 |
| 20130012578 | Novel Formulations of Bifenthrin and Enriched Cypermethrin - The present invention is directed to novel insecticidal compositions comprising bifenthrin and enriched cypermethrin, the compositions are physically stable when diluted with water. | 01-10-2013 |
| 20130018098 | PYRETHRINOID-TYPE ESTERS AS PESTICIDESAANM Matsuo; NoritadaAACI Amagasaki-shiAACO JPAAGP Matsuo; Noritada Amagasaki-shi JPAANM Mori; TatsuyaAACI Toyonaka-shiAACO JPAAGP Mori; Tatsuya Toyonaka-shi JP - An ester compound represented by formula (1): wherein R | 01-17-2013 |
| 20130023587 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF CANCER - Provided are methods for inhibiting survival of a proliferating, quiescent, or hypoxic cancer cell that include administering a compound that inhibits lactate clearance (e.g., lactate catabolism, lactate transport, glutamate release, and/or alanine release) in the proliferating, quiescent, or hypoxic cancer cell. Further provided are methods of reducing the proliferation of a neoplastic cell having increased lactate or decreased glucose concentrations relative to a normal cell. Also provided are methods of treating a subject having cancer, wherein the methods may include administering to the subject an inhibitor of lactate clearance. | 01-24-2013 |
| 20130123356 | MODULATOR - The present invention relates to a compound of formula (I), or a pharmaceutically acceptable salt thereof, | 05-16-2013 |
| 20130172409 | PEST CONTROLLING METHOD, COMPOSITION, ELECTROSTATIC SPRAY DEVICE AND USE THEREOF - Disclosed is a composition containing an ester compound represented by formula (1), which composition is electrostatically sprayed to pests or to a place where the pests inhabit. | 07-04-2013 |
| 20130197080 | USE OF TERIFLUNOMIDE FOR TREATING MULTIPLE SCLEROSIS - This invention relates to use of teriflunomide for treating Multiple Sclerosis (MS) and managing the risks associated with the use of teriflunomide. | 08-01-2013 |
| 20130217766 | FORMULATIONS FOR CATHEPSIN K INHIBITORS - The instant invention relates to pharmaceutical compositions containing cathespin K inhibitors. Also disclosed are processes for making said pharmaceutical compositions. | 08-22-2013 |
| 20130253054 | Pesticidal composition containing lambda cyhalothrin and diafenthiuron. - The present invention relates to a composition comprising an effective amount of lambda cyhalothrin in the range of 0.5% to 12%; an effective amount of diafenthiuron in the range of 15% to 70% wherein the ratio of lambda cyhalothrin to diafenthiuron is in the range of 1:4 to 1:35; and at least one agrochemical excipient. | 09-26-2013 |
| 20130274330 | ORAL DOSAGE FORM - An oral dosage form of entacapone and methods for the preparation thereof are provided. | 10-17-2013 |
| 20130338223 | PESTICIDAL COMPOSITIONS - The present invention relates to compositions for the control of pests, to processes for their preparation, and to methods of treating surfaces with such formulations for the sustained weather-resistant control of pests. The composition includes a pesticide and an aqueous polymer dispersion. | 12-19-2013 |
| 20140018421 | DI-FLUORO CONTAINING COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS - The present invention is directed to compounds that are inhibitors of cysteine proteases, in particular, cathepsins B, K, L, F, and S, and are therefore useful in treating diseases mediated by these proteases. The present invention is directed to pharmaceutical compositions comprising these compounds and processes for preparing them. | 01-16-2014 |
| 20140051755 | Continuous Administration of L-Dopa, Dopa Decarboxylase Inhibitors, Catechol-O-Methyl Transferase Inhibitors and Compositions for Same - Provided herein, in part, is a method of treating a neurological or movement disorder in a patient in need thereof, comprising subcutaneously administering to said patient a pharmaceutically acceptable composition comprising levodopa and optionally carbidopa and optionally entacapone or tolcapone, or pharmaceutically acceptable salts thereof, wherein said composition is administered substantially continuously, and compositions that can be used in the disclosed methods. | 02-20-2014 |
| 20140148510 | IMPROVED METHOD FOR PRODUCING EMULSIFIABLE PESTICIDE SOLUTIONS - The current invention provides a kit of parts for producing an emulsifiable pesticide solution comprising: (a) a water miscible organic solvent selected from the list of a glycol ether, a glycerol formal, dimethylsulfoxide, gamma-butyrolactone or mixtures thereof, (b) an alkoxylated alcohol with an average of 6 to 80 moles of ethylene oxide and 2 to 60 moles of propylene oxide per mole of alcohol; and (c) a pesticidal active ingredient. The invention further provides a composition for producing an emulsifiable pesticide solution, a method for producing such a composition and a method for treating an agricultural crop. In addition the invention provides some advantageous pesticidal compositions. | 05-29-2014 |
| 20140221478 | DI-FLUORO CONTAINING COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS - The present invention is directed to compounds that are inhibitors of cysteine proteases, in particular, cathepsins B, K, L, F, and S, and are therefore useful in treating diseases mediated by these proteases. The present invention is directed to pharmaceutical compositions comprising these compounds and processes for preparing them. | 08-07-2014 |
| 20140243408 | USE OF AMINOACETONITRILE DERIVATIVES AGAINST ENDOPARASITES - The present invention relates to a method of treating a parasitic infection in an animal, particularly a filarial endoparasitic infection, comprising administering an effective amount of a Formula (I) compound or a Formula (II) compound | 08-28-2014 |
| 20140296335 | SHORT ACTING PHENYLALKYLAMINE CALCIUM CHANNEL BLOCKERS AND USES THEREOF - The present invention relates to the use of a pharmaceutically effective amount of an short-acting calcium channel blocking compound to treat ischemic heart conditions, cardiac arrhythmias, hypertensive crisis in an emergency room setting, hypertension before, during, or after surgery, no-reflow phenomenon following reperfusion, and diseases associated with decreased skeletal muscle blood flow. The invention also relates to pharmaceutical compositions formulated for use in such methods and to kits for such methods. | 10-02-2014 |
| 20140315998 | PEST CONTROL COMPOSITION - A pest control composition is provided having an excellent control effect on pests and containing an ester compound represented by the following formula (1) and diethyl adipate. A method is also provided for controlling pests including applying the pest control composition to pests or habitats of pests. | 10-23-2014 |
| 20140329901 | COMPOUNDS FOR TREATMENT OF CELL PROLIFERATIVE DISEASES - The present invention concerns compounds and their use to treat cell proliferative diseases such as cancer. Compounds of the present invention display significant potency as kinase inhibitors, cause the downregulation of c-myc, and inhibit the growth and survival of cancerous cell lines. | 11-06-2014 |
| 20160022573 | METHOD FOR TREATMENT OF PARKINSON'S DISEASE - The present invention provides a method for treatment of a neurological or movement disorder, e.g., Parkinson's disease, in an individual in need thereof, by parenteral administration of a composition comprising carbidopa and levopoda, or pharmaceutically acceptable salts thereof, and concomitant oral administration of a catechol-O-methyl transferase (COMT) inhibitor, e.g., entacapone or tolcapone. | 01-28-2016 |
| 20160074354 | SHORT ACTING PHENYLALKYLAMINE CALCIUM CHANNEL BLOCKERS AND USES THEREOF - The present invention relates to the use of a pharmaceutically effective amount of an short-acting calcium channel blocking compound to treat ischemic heart conditions, cardiac arrhythmias, hypertensive crisis in an emergency room setting, hypertension before, during, or after surgery, no-reflow phenomenon following reperfusion, and diseases associated with decreased skeletal muscle blood flow. The invention also relates to pharmaceutical compositions formulated for use in such methods and to kits for such methods. | 03-17-2016 |
| 20160081937 | TABLET WITH INCREASED DRUG LOAD OF ODANACATIB - The present invention relates to pharmaceutical tablets comprising amorphous compound I or pharmaceutically acceptable salts thereof, and an inert organic carrier. | 03-24-2016 |
| 20160107984 | MODULATOR - The present disclosure relates to a compound of formula (I), or a pharmaceutically acceptable salt thereof, wherein Z is selected from OH, NHCH | 04-21-2016 |
| 20160151317 | Continuous Administration of Dopa Decarboxylase Inhibitors and Compositions for Same | 06-02-2016 |
| 20160185717 | COMPOUNDS WITH ANTIBACTERIAL ACTIVITY - The present invention relates to compounds of general formula (I) | 06-30-2016 |
| 20160199342 | 4-(PHENOXYALKYL)THIO)-PHENOXYACETIC ACIDS AND ANALOGS | 07-14-2016 |
| 20160374982 | SHORT ACTING PHENYLALKYLAMINE CALCIUM CHANNEL BLOCKERS AND USES THEREOF - The present invention relates to the use of a pharmaceutically effective amount of an short-acting calcium channel blocking compound to treat ischemic heart conditions, cardiac arrhythmias, hypertensive crisis in an emergency room setting, hypertension before, during, or after surgery, no-reflow phenomenon following reperfusion, and diseases associated with decreased skeletal muscle blood flow. The invention also relates to pharmaceutical compositions formulated for use in such methods and to kits for such methods. | 12-29-2016 |
| 20190142781 | SHORT ACTING PHENYLALKYLAMINE CALCIUM CHANNEL BLOCKERS AND USES THEREOF | 05-16-2019 |
| 514522000 | The cyano is bonded directly to a benzene ring | 32 |
| 20100022641 | SOLID FORMS OF SELECTIVE ANDROGEN RECEPTOR MODULATORS - The present invention relates to solid forms of (S)—N-(4-cyano-3-(trifluoromethyl)phenyl)-3-(4-cyanophenoxy)-2-hydroxy-2-methylpropanamide and process for producing the same. | 01-28-2010 |
| 20100137430 | TREATING ANDROGEN DECLINE IN AGING MALE (ADAM)-ASSOCIATED CONDITIONS WITH SARMS - This invention provides methods for treatment and inhibition of a male subject having an Androgen Decline in Aging Male (ADAM)-associated condition, for example sexual dysfunction, decreased sexual libido, erectile dysfunction, hypogonadism, sarcopenia, osteopenia, osteoporosis, an alteration in cognition and mood, depression, anemia, hair loss, obesity, muscle loss, dry eye, memory loss, benign prostate hyperplasia and/or prostate cancer, by administering to the subject a selective androgen receptor modulator (SARM) compound and/or its analog, derivative, isomer, metabolite, pharmaceutically acceptable salt, pharmaceutical product, hydrate, N-oxide, pro-drug, polymorph, crystal, or any combination thereof. | 06-03-2010 |
| 20100144871 | Treating muscle wasting with selective androgen receptor modulators - This invention provides: 1) a method of treating a subject suffering from a muscle wasting disorder; 2) a method of preventing a muscle wasting disorder in a subject; 3) a method of treating, preventing, suppressing, inhibiting or reducing muscle loss in a subject suffering from a muscle wasting disorder; 4) a method of treating, preventing, inhibiting, reducing or suppressing muscle wasting in a subject suffering from a muscle wasting disorder; and/or 5) a method of treating, preventing, inhibiting, reducing or suppressing muscle protein catabolism in a subject suffering from a muscle wasting disorder, by administering to the subject a selective androgen receptor modulator (SARM) and/or an analog, derivative, isomer, metabolite, pharmaceutically acceptable salt, pharmaceutical product, hydrate, N-oxide, prodrug, polymorph, impurity or crystal of said SARM compound, or any combination thereof. | 06-10-2010 |
| 20100249228 | SARMS AND METHOD OF USE THEREOF - This invention is directed to a feed composition and method of affecting the carcass composition by increasing the lean mass, reducing the fat mass, and/or reducing the percent fat mass comprising SARM compounds. | 09-30-2010 |
| 20100280107 | TREATING BENIGN PROSTATE HYPERPLASIA WITH SARMS - This invention provides a method of treating, preventing, suppressing, inhibiting or reducing the incidence of benign prostate hyperplasia in a male subject, by administering to the subject a selective androgen receptor modulator (SARM) and/or its analog, derivative, isomer, metabolite, pharmaceutically acceptable salt, pharmaceutical product, hydrate, N-oxide, or any combination thereof as described herein. This invention also provides a method of treating a subject suffering from hair loss, comprising the step of administering to the subject a therapeutically effective amount of a 5-α reductase enzyme type 1 and/or type 2 inhibitor, wherein said inhibitor is a selective androgen receptor modulator (SARM) and/or its analog, derivative, isomer, metabolite, pharmaceutically acceptable salt, pharmaceutical product, hydrate, N-oxide, or any combination thereof as described herein. This invention also provides a method of inhibiting a 5-α reductase type 1 and/or type 2 enzyme, comprising contacting the enzyme with an effective 5-α reductase inhibitory amount of a selective androgen receptor modulator (SARM) and/or its analog, derivative, isomer, metabolite, pharmaceutically acceptable salt, pharmaceutical product, hydrate, N-oxide, or any combination thereof, as described herein. | 11-04-2010 |
| 20110172302 | METHODS OF TREATING MEIBOMIAN GLAND DYSFUNCTION - The present invention includes methods for treating Meibomian gland dysfunctions. The invention also includes methods for improving tear lipid composition, for treating abnormal Meibomian gland secretion and for normalizing Meibomian gland secretions. | 07-14-2011 |
| 20110237664 | SELECTIVE ANDROGEN RECEPTOR MODULATORS FOR TREATING DIABETES - This invention provides use of a SARM compound or a composition comprising the same in treating and preventing muscle wasting in patients with non-small cell lung cancer (NSCLC); treating pre-cachexia or early cachexia (preventing muscle wasting in a cancer patient); treating and preventing loss of physical function due to cancer or cancer therapy; increase of physical function; and increasing survival in a patient with NSCLC. | 09-29-2011 |
| 20110237665 | Agrochemical Composition Comprising Pesticide and UV Absorber - The present invention relates to an agrochemical composition comprising pesticide and UV absorber, and the abovementioned UV absorbers. The invention furthermore relates to the use of the UV absorbers in agrochemical compositions. It moreover relates to a method of controlling phytopathogenic fungi and/or undesirable plant growth and/or undesirable insect or mite infestation and/or of regulating plant growth. | 09-29-2011 |
| 20110257265 | UV Absorbers for Reducing the E/Z Isomerization of Pesticides - The present invention provides the use of a UV absorber for reducing the E/Z isomerization of pesticides comprising a double bond. It furthermore relates to a composition comprising an E and/or a Z isomer of a pesticide comprising a double bond and a UV absorber. | 10-20-2011 |
| 20110263703 | SOLID FORMS OF SELECTIVE ANDROGEN RECEPTOR MODULATORS - The present invention relates to solid forms of (S)-N-(4-cyano-3-(trifluoromethyl)phenyl)-3-(4-cyanophenoxy)-2-hydroxy-2-methylpropanamide and process for producing the same. | 10-27-2011 |
| 20120122975 | 4-CYANO-3-BENZOYLAMINO-N-PHENYL-BENZAMIDES FOR USE IN PEST CONTROL - The present invention relates to bis-amide derivatives of formula (I), to processes and intermediates for preparing them, to methods of using them to control insect, acarine, nematode and mollusc pests, and to insecticidal, acaricidal, nematicidal and molluscicidal compositions comprising them. | 05-17-2012 |
| 20120136052 | SUBSTITUTED ACYLANILIDES AND METHODS OF USE THEREOF - This invention provides SARM compounds and uses thereof in treating a variety of diseases or conditions in a subject, including, inter alia, a muscle wasting disease and/or disorder or a bone-related disease and/or disorder. | 05-31-2012 |
| 20120142771 | BIPHENYLACETAMIDE DERIVATIVE - The present invention provides a compound of formula (I) or a salt thereof, wherein R | 06-07-2012 |
| 20120232138 | AMIDOACETONITRILE COMPOUNDS HAVING PESTICIDAL ACTIVITY - Novel amidoacetonitrile compounds and compositions containing the compounds are disclosed. The compounds have pesticidal properties and are suitable for controlling endoparasites on warm-blooded animals. | 09-13-2012 |
| 20120264823 | SUBSTITUTED HETEROARYL- AND ARYL-CYCLOPROPYLAMINE ACETAMIDES AND THEIR USE - The invention relates to compounds of Formula (I): (A′) | 10-18-2012 |
| 20130035387 | SARMS AND METHOD OF USE THEREOF - This invention is directed to a feed composition and method of affecting the carcass composition by increasing the lean mass, reducing the fat mass, and/or reducing the percent fat mass comprising SARM compounds. | 02-07-2013 |
| 20130158112 | COMPOSITIONS AND METHODS FOR INHIBITING BETA AMYLOID SECRETION - A pharmaceutical composition for inhibiting amyloid beta peptide in a subject includes a compound having the formula (I): | 06-20-2013 |
| 20130184343 | INSECTICIDAL COMPOUNDS - A compound of formula (I): | 07-18-2013 |
| 20130190396 | NOVEL SULFONAMIDE COMPOUNDS FOR INHIBITION OF METASTATIC TUMOR GROWTH - Therapeutic ureido-sulfonamide compositions having compounds with the formula | 07-25-2013 |
| 20130296422 | Novel Dihydroxybenzene Derivatives and Antiprotozoal Agent Comprising Same as Active Ingredient - Novel compounds below are useful for preventing or treating diseases caused by protozoans. At least one of a compound represented by Formula (I) | 11-07-2013 |
| 20130324602 | SUBSTITUTED ACYLANILIDES AND METHODS OF USE THEREOF - This invention provides SARM compounds and uses thereof in treating a variety of diseases or conditions in a subject, including, inter alia, a muscle wasting disease and/or disorder or a bone-related disease and/or disorder. | 12-05-2013 |
| 20140005263 | TREATING ANDROGEN DECLINE IN AGING MALE (ADAM)-ASSOCIATED CONDITIONS WITH SARMS | 01-02-2014 |
| 20140018422 | DERIVATIVES OF TETRACAINE - Disclosed herein are derivatives of tetracaine that, among other things, block cyclic nucleotide gated (CNG) channels and are useful in the treatment of diseases characterized by overactive CNG channels such as retinal degeneration diseases. | 01-16-2014 |
| 20140080905 | METHOD OF TREATING ESTROGEN RECEPTOR (ER) -POSITIVE BREAST CANCERS WITH SELECTIVE ANDROGEN RECEPTOR MODULATOR (SARMS) - This invention relates to the treatment of androgen receptor-positive breast cancer in a subject, for example a female subject. Accordingly, this invention provides methods of: a) treating a subject suffering from breast cancer; b) treating a subject suffering from metastatic breast cancer; c) treating a subject suffering from refractory breast cancer; d) treating a subject suffering from AR-positive breast cancer; e) treating a subject suffering from AR-positive refractory breast cancer; f) treating a subject suffering from AR-positive metastatic breast cancer; g) treating a subject suffering from AR-positive and ER-positive breast cancer; h) treating a subject suffering from triple negative breast cancer; i) treating a subject suffering from advanced breast cancer; j) treating a subject suffering from breast cancer that has failed SERM (tamoxifen, toremifene), aromatase inhibitor, trastuzumab (Herceptin, ado-trastuzumab emtansine), pertuzumab (Perjeta), lapatinib, exemestane (Aromasin), bevacizumab (Avastin), and/or fulvestrant treatments; k) treating, preventing, suppressing or inhibiting metastasis in a subject suffering from breast cancer; l) prolonging survival of a subject with breast cancer, and/or m) prolonging the progression-free survival of a subject with breast cancer; comprising administering to the subject a therapeutically effective amount of a selective androgen receptor modulator (SARM) compound, comprising administering to the subject a therapeutically effective amount of a SARM compound of this invention. | 03-20-2014 |
| 20140171503 | NUCLEAR RECEPTOR MODULATORS AND THEIR USE FOR THE TREATMENT AND PREVENTION OF CANCER - Disclosed are compounds which are nuclear receptor modulators that can act as antagonists to the androgen receptor, for example, a compound of Formula I: wherein R | 06-19-2014 |
| 20140221479 | SARMS AND METHOD OF USE THEREOF - This invention is directed to a feed composition and method of affecting the carcass composition by increasing the lean mass, reducing the fat mass, and/or reducing the percent fat mass comprising SARM compounds. | 08-07-2014 |
| 20140350102 | METHOD OF TREATING ANDROGEN RECEPTOR (AR) -POSITIVE BREAST CANCERS WITH SELECTIVE ANDROGEN RECEPTOR MODULATOR (SARMS) - This invention relates to the treatment of breast cancer in a subject, for example a female subject. Including methods of: treating metastatic breast cancer; refractory breast cancer; AR-positive breast cancer; AR-positive refractory breast cancer; AR-positive metastatic breast cancer; AR-positive and ER-positive breast cancer; triple negative breast cancer advanced breast cancer; breast cancer that has failed SERM (tamoxifen, toremifene), aromatase inhibitor, trastuzumab (Herceptin, ado-trastuzumab emtansine), pertuzumab (Perjeta), lapatinib, exemestane (Aromasin), bevacizumab (Avastin), and/or fulvestrant treatments; metastasis in a subject suffering from breast cancer; comprising administering to the subject a therapeutically effective amount of a selective androgen receptor modulator (SARM) compound. | 11-27-2014 |
| 20160089356 | SUBSTITUTED ACYLANILIDES AND METHODS OF USE THEREOF - This invention provides substituted acylanilide compounds and uses thereof in treating a variety of diseases or conditions in a subject, including, inter alia, a muscle wasting disease and/or disorder such as muscular dystrophies including Duchenne muscular dystrophy and Becker muscular dystrophy. | 03-31-2016 |
| 20160128968 | METHOD OF TREATING ANDROGEN RECEPTOR (AR) -POSITIVE BREAST CANCERS WITH SELECTIVE ANDROGEN RECEPTOR MODULATOR (SARMS) - This invention relates to the treatment of breast cancer in a subject, for example a female subject. Including methods of: treating metastatic breast cancer; refractory breast cancer; AR-positive breast cancer; AR-positive refractory breast cancer; AR-positive metastatic breast cancer; AR-positive and ER-positive breast cancer; triple negative breast cancer; advanced breast cancer; breast cancer that has failed SERM (tamoxifen, toremifene), aromatase inhibitor, trastuzumab (Herceptin, ado-trastuzumab emtansine), pertuzumab (Perjeta), lapatinib, exemestane (Aromasin), bevacizumab (Avastin), and/or fulvestrant treatments; metastasis in a subject suffering from breast cancer; comprising administering to the subject a therapeutically effective amount of a selective androgen receptor modulator (SARM) compound. | 05-12-2016 |
| 20160128969 | SOLID FORMS OF SELECTIVE ANDROGEN RECEPTOR MODULATORS - The present invention relates to solid forms of (S)—N-(4-cyano-3-(trifluoromethyl)phenyl)-3-(4-cyanophenoxy)-2-hydroxy-2-methylpropanamide and process for producing the same. | 05-12-2016 |
| 20160158185 | SARMS AND METHOD OF USE THEREOF - This invention is directed to substituted acylanilide compounds and uses thereof in treating a variety of diseases or conditions in a subject, including, inter alia, a muscle wasting disease and/or disorder such as Duchenne muscular dystrophy or Becker muscular dystrophy. | 06-09-2016 |
| 20160166530 | SELECTIVE ANDROGEN RECEPTOR MODULATOR AND METHODS OF USE THEREOF | 06-16-2016 |
