| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 514509000 | (O=)N(=O)-O-C containing (e.g., nitrate ester, etc.) | 15 |
| 20090170934 | MANUFACTURING PROCESS FOR NO-DONATING COMPOUNDS SUCH AS NO-DONATING DICLOFENAC - The present invention relates to a new process for the preparation of NO-donating compounds using a sulfonated intermediate. The invention relates to new intermediates prepared therein suitable for large scale manufacturing of NO-donating compounds. The invention further relates to the use of the new intermediates for the manufacturing of pharmaceutically active NO-donating compounds. The invention further relates to a substantially crystalline form of NO-donating NSAIDs, especially 2-[2-(nitrooxy)ethoxy]ethyl {2-[(2,6-dichlorophenyl)amino]phenyl}acetate, the preparation thereof and to pharmaceutical formulations containing said crystalline form and to the use of said crystalline form in the preparation of a medicament. | 07-02-2009 |
| 20100227922 | Long-term stable pharmaceutical preparation containing the active ingredient glyceryl trinitrate - A pharmaceutical preparation containing the active substance glyceryl trinitrate having improved storage stability in a container. The improved storage stability is achieved by the addition of a proton-absorbing substance either as part of the preparation as placed into the container or applied to the surface of the preparation's storage container before the remaining components of the preparation are placed into the container. The preparation can preferably be filled into a plastic bottle having a spray pump. | 09-09-2010 |
| 20100240745 | METHOD OF TREATMENT OF INFLAMMATION IN HYPERTENSIVE PATIENTS - The present invention relates to the use of 4-(nitrooxy)-butyl-(S)-2-(6-methoxy-2-naphthyl)-propanoate (naproxcinod) for the treatment of pain and/or inflammation in patients with hypertension treated with renin-angiotensin system blocking agents. | 09-23-2010 |
| 20100286264 | COMPOSITION COMPRISING A NITROOXYDERIVATIVE OF ACETAMINOPHEN AND A ANTICONVULSANT DRUG FOR THE TREATMENT OF NEUROPATHIC PAIN - The present invention relates to compositions comprising a nitric oxide releasing paracetamol and an anticonvulsant drug. The compositions of the invention can be used use in the treatment of neuropathic pain in particular diabetic neuropathic pain, painful post-infarct syndrome, pain caused by chemotherapeutic treatment or pain arising from infections by viral agents. | 11-11-2010 |
| 20100331405 | Methods of Treating Term and Near-Term Neonates Having Hypoxic Respiratory Failure Associated with Clinical or Echocardiographic Evidence of Pulmonary Hypertension - The invention relates methods of reducing the risk or preventing the occurrence of an adverse event (AE) or a serious adverse event (SAE) associated with a medical treatment comprising inhalation of nitric oxide. | 12-30-2010 |
| 20110054020 | NAPTHYLENE INHIBITORS OF CYCLOOXYGENASE - The present invention relates to new napthylene inhibitors of cyclooxygenase activity, pharmaceutical compositions thereof, and methods of use thereof | 03-03-2011 |
| 20110092590 | NITRIC OXIDE DONATING PROSTAMIDES - Nitroderivatives of prostaglandins having improved pharmacological activity and enhanced tolerability are described. They can be employed for the treatment of glaucoma and ocular hypertension. | 04-21-2011 |
| 20110130455 | Nitrate Esters and Their Use For The Treatment of Muscle and Muscle Related Diseases - Alkyl nitrate ester compounds are provided for the delivery of nitric oxide to targeted muscle tissues, and in particular, to normal and dystrophic muscles. In one aspect, nitrate ester compounds are provided having the following formula: | 06-02-2011 |
| 20110160302 | DEVICE AND METHODS FOR TREATMENT AND PREVENTION OF TENDON INJURIES - The present invention relates to treatment and prevention devices and regimens for tendon injury and damage. The invention further provides compositions comprising therapeutic agents and the use of such compositions in methods of treating disorders, injuries and conditions beneficially treated by these agents, particularly those relating to the management of tendon damage. | 06-30-2011 |
| 20120035259 | Controlled Release of Nitric Oxide And Drugs From Functionalized Macromers And Oligomers - The present invention provides NO and, optionally, drug releasing macromers and oligomers wherein the drug molecule and NO releasing moiety are linked an absorbable macromer or oligomeric chain susceptible to hydrolytic degradation and wherein the macromer or oligomer comprises of repeat units derived from safe and biocompatible molecules such as glycolic acid, lactic acid, caprolactone and p-dioxanone. Furthermore, the present invention relates to controlled release of nitric oxide (NO) and/or drug molecule from a NO and drug releasing macromer or oligomer. Moreover, the present invention also relates to medical devices, medical device coatings and therapeutic formulations comprising of nitric oxide and drug releasing macromers and oligomers of the present invention. | 02-09-2012 |
| 20120289593 | METHODS FOR RISK ASSESSMENT, TREATING, AND DIAGNOSING MYOCARDIAL INFARCTION - This document features method related to genetic markers associated with myocardial infarction. For example, methods of using such genetic markers for risk assessment and for diagnosing and treating myocardial infarction are provided. | 11-15-2012 |
| 20130137765 | USE OF NITROOXYDERIVATIVE OF DRUG FOR THE TREATMENT OF MUSCULAR DYSTROPHIES - The present invention relates to the use of nitric oxide releasing compounds for retarding or reversing muscular dystrophies such as Duchenne and Becker dystrophies. | 05-30-2013 |
| 20140066502 | Use of Stabilized Granules Containing Glyceryl Trinitrate for Arteriogenesis - The present invention inter alia relates to a method of treating or preventing an arterial insufficiency, wherein an NO donor is administered in an intermitting manner to a subject in an amount effective for the induction of arteriogenesis, and wherein the NO donor is a solid pharmaceutical preparation with the active substance glyceryl trinitrate for oromucosal or oral administration characterized in that it contains between 0.05 and 2 weight % glyceryl trinitrate (GTN), at least one diluent, one carrier material, and at least one substance that reduces the volatility of GTN, whereby this substance is a non-volatile ester stabilizer whose melting point is not higher than 60° C. | 03-06-2014 |
| 20140309299 | Stabilized Pharmaceutical Preparations in Containers Having Limited Perviousness to Water Vapor - The present invention relates to a pharmaceutical preparation, comprising a mixture of at least one pharmaceutical active ingredient, at least one alcohol component and at least one triglyceride component, in a plastic container, characterized in that the plastic has a water vapour permeability of no more than 3.0 g/m | 10-16-2014 |
| 20150141505 | BRONCHOLYTIC DRUG ON THE BASIS OF PROSTAGLANDIN - The invention relates to the field of medicine, and specifically to pulmonology, and concerns a method for treating inflammatory and obstructive diseases of the airways, in particular bronchial asthma and obstructive bronchitis, with the aid of a drug on the basis of 1′,3′-dinitroglycerol ester 11(S),15(S)-dihydroxy-9-keto-5Z,13E-prostadienoic acid (nitroproston) having a marked bronchodilatory effect. The present invention provides for an expansion of the range of broncholytic drugs by the use of a derivative of natural prostaglandin E | 05-21-2015 |
