| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 514459000 | Nitrogen containing | 39 |
| 20090076133 | DEUTERIUM-ENRICHED ZANAMIVIR - The present application describes deuterium-enriched zanamivir, pharmaceutically acceptable salt forms thereof, and methods of treating using the same. | 03-19-2009 |
| 20090156666 | NOVEL COMPOSITIONS AND USE THEREOF FOR THE TREATMENT, CO-TREATMENT OR PREVENTION OF INFLAMMATORY DISORDERS - The present invention relates to novel compositions comprising magnolol and/or honokiol and glucosamine as well as to the use of these compositions as a medicament, in particular as a medicament for the treatment, co-treatment or prevention of inflammatory disorders. | 06-18-2009 |
| 20090215886 | Anti-Inflammatory Formulation - Compositions comprising apocynin and paeonol. The compositions may be used for the treatment of inflammatory disease. | 08-27-2009 |
| 20090221697 | MACROLIDE CONJUGATES OF PYRROLIZINE AND INDOLIZINE COMPOUNDS AS INHIBITORS OF 5-LIPOOXYGENASE AND CYCLOOXYGENASE - The present invention relates to macrolide conjugates of pyrrolizine and indolizine derivatives with macrocyclic antibiotics and derivatives thereof. The macrolide conjugates are potent inhibitors of 5-lipoxygenase and cyclooxygenase and are therefore suitable to treat disorders of the rheumatic type and to prevent allergically induced diseases. The macrolide conjugates have significantly enhanced potency and efficacy. | 09-03-2009 |
| 20090275651 | Alcanoic Acid Amides Substituted by Saturated O-Heterocycles - Compounds of the general formula (formula I) in which the meanings of the substituents R1 to R6 are as indicated in claim | 11-05-2009 |
| 20100004326 | METABOLITES OF SELECTIVE ANDROGEN RECEPTOR MODULATORS AND METHODS OF USE THEREOF - This invention provides metabolites of SARM compounds including inter alia glucuronidated metabolites and uses thereof in treating a variety of diseases or conditions in a subject, including, inter alia, muscle wasting disease and/or disorder, a bone related disease and/or disorder, metabolic syndrome, diabetes and associated diseases, and others. | 01-07-2010 |
| 20100022637 | IDENTIFICATION OF ANTI-CANCER COMPOUNDS AND COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE AND METHODS OF TREATMENT THEREOF - Small molecule screening via high-throughput screening (HTS) methods was employed to identify compounds useful for treating or preventing cancer (such as compounds that enable cells to overcome E6-oncoprotein-mediated drug resistance) or neurodegenerative disorders (such as Huntington's disease, HD). Compounds were identified that potentiate the lethality of anti-tumor agents as well as rescue a disease-state lethality. These compounds are acylated secondary amines referred to herein as indoxins and revertins. | 01-28-2010 |
| 20100081713 | COMPOSITIONS AND METHODS FOR TREATING VIRAL INFECTIONS - The present invention provides compositions, methods, and kits for treating or preventing a viral infection (e.g., an infection caused by an influenza virus). | 04-01-2010 |
| 20100204314 | DRUG FOR TREATMENT OF INFLUENZA - A therapeutic or prophylactic for H5N1 influenza is provided. | 08-12-2010 |
| 20100249225 | C-(2-Phenyl-Cyclohexyl)-Methylamine Compounds for the Treatment of Anxiety Disorders - Pharmaceutical formulations of [2-(3-methoxyphenyl)-cyclohexylmethyl]-dimethylamine and the metabolites thereof for treating anxiety, anxiety attacks and disorders as well as depression. Related methods of treating anxiety and anxiety attacks or depression are also provided, including methods of administering the active compounds as adjuvants to an antidepressant. | 09-30-2010 |
| 20110112185 | INSECTICIDAL FERMENTATION BROTH FROM ACTINOMYCETES - Methods and compositions are provided for the preparation of insecticidal compositions. | 05-12-2011 |
| 20110144197 | ALCANOIC ACID AMIDES SUBSTITUTED BY SATURATED O-HETEROCYCLES - Compounds of the general formula (formula I) | 06-16-2011 |
| 20110160300 | Renin Inhibitors and Methods of Use Thereof - Disclosed are aspartic protease inhibitors represented by the following Formula: wherein R | 06-30-2011 |
| 20110245335 | NEW INHIBITORS FOR TREATING DISEASES ASSOCIATED WITH AN EXCESS TRANSPORT OF HYALURONAN - The present invention relates in general to a compound which is characterized by a formula selected from the following formulas A, B, C, D, E or F; or a pharmaceutically acceptable salt thereof. The present invention further relates to pharmaceutical composition comprising the inhibitor(s) of the invention and to their use in the treatment of (for treating) a disease which is associated with an excess transport of hyaluronan across a lipid bilayer. The present invention furthermore relates to the use of at least one inhibitor of the invention for the preparation of a pharmaceutical composition for the treatment of (for treating) a disease which is associated with an excess transport of hyaluronan across a lipid bilayer. The present invention also relates to a method for manufacturing a pharmaceutical composition comprising the steps of formulating the inhibitor defined herein in a pharmaceutically acceptable form. | 10-06-2011 |
| 20110263699 | 1-Phenyl-2-DimethylaminomethylCyclohexane Compounds and Therapies for Depressive Symptoms, Pain and Incontinence - Metabolites of [2-(3-methoxyphenyl)-cyclohexylmethyl]dimethylamine as free bases and/or in the form of physiologically acceptable salts, corresponding medicaments, the use of [2-(3-methoxyphenyl)-cyclohexylmethyl]-dimethylamine and the metabolites thereof for producing a medicament used for treating depression, and related methods of treating depression, pain and urinary incontinence. | 10-27-2011 |
| 20120004298 | OPHTHALMIC DEVICES CONTAINING CHEMOKINE ANTAGONISTS - Ionic ophthalmic devices, methods of treating chemoattractant cytokine receptor 2 (CCR2) mediated inflammatory conditions, and methods of making such devices are disclosed herein. | 01-05-2012 |
| 20120016017 | PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING CANCER - The present invention relates to a compound of the formula I: | 01-19-2012 |
| 20120016018 | COMPOSITION FOR INDUCING MULTIPLE NUCLEAR DIVISION OF CELLS - The present invention relates to the novel use of a composition comprising a compound of the formula I: | 01-19-2012 |
| 20120016019 | PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING CANCER - The present invention relates to a compound of the formula I: | 01-19-2012 |
| 20120035255 | DERIVATIVE OF [(3-HYDROXY-4 PYRON-2-YL)-METHYL]-AMINE AND USE THEREOF AS ANTI-NEOPLASTIC DRUGS - The present invention relates to compounds having general formula (I), i.e. poly-alkyl-bis-maltolic molecules and in particular to derivates of [(3-hydroxy-4-pyron-2-yl)methyl]-amine and pharmaceutically acceptable salts thereof, and to the use thereof as anti-neoplastic drugs, in particular, for the preparation of a medicament for the treatment of neoplastic diseases. | 02-09-2012 |
| 20120046355 | INHIBITORS OF SIALIDASE OR SIALIDASE-LIKE ENZYMES - The present invention describes compounds of Formula I or a pharmaceutically acceptable salts or derivatives thereof. Compositions comprising compounds of Formula I are also described. The present invention further relates to a method of producing non-2-enonate compounds. | 02-23-2012 |
| 20120077876 | Method For Improved Bioactivation Of Pharmaceuticals - This invention relates to a prodrug comprising a partial structure having the general formula (I) or (II), where R | 03-29-2012 |
| 20120178802 | 2,3-Fluorinated Glycosides as Neuraminidase Inhibitors and Their Use as Anti-Virals - Compounds of structural formula (I) useful for the treatment or prophylaxis of viral infection, particularly viral influenza are provided Pharmaceutical preparations thereof and methods for their preparation are also described. The therapeutic effect is achieved via inhibition of viral neuraminidases, also known as viral sialidases. These neuraminidases are classified under the GH34 family of viral enzymes. | 07-12-2012 |
| 20120184606 | NEURAMINIDASE INHIBITOR COMPOUNDS, COMPOSITIONS AND METHODS FOR THE USE THEREOF IN ANTI-VIRAL TREATMENTS - Compounds having a structure of Formula I and compositions comprising these compounds are provided. Uses of such compounds and compositions are provided for treatment or prophylaxis of viral infection. In particular, compounds and compositions may be for use in the treatment or prophylaxis of viral influenza. | 07-19-2012 |
| 20130005799 | THE USE OF FENOTEROL AND FENOTEROL ANALOGUES IN THE TREATMENT OF GLIOBLASTOMAS AND ASTROCYTOMAS - This disclosure concerns the discovery of the use of fenoterol and (R,R)- and (R,S)-fenoterol analogues for the treatment of a tumor expressing a β2-adrenergic receptor, such as a primary brain tumor, including a glioblastoma or astrocytoma expressing a β2-adrenergic receptor. In one example, the method includes administering to a subject a therapeutically effective amount of fenoterol, a specific fenoterol analogue or a combination thereof to reduce one or more symptoms associated with the tumor, thereby treating the tumor in the subject. | 01-03-2013 |
| 20130023585 | Neuraminidase Inhibitors - Disclosed are neuraminidase inhibitor compounds and pharmaceutical compositions with improved bioavailability and/or improved efficacy and methods of treating influenza using the compounds and pharmaceuticals compositions. | 01-24-2013 |
| 20130030048 | COMPOSITION FOR INDUCING MULTIPLE NUCLEAR DIVISION OF CELLS - The present invention relates to the novel use of a composition comprising a compound of the formula I: | 01-31-2013 |
| 20130197072 | METHOD FOR MANUFACTURING NEURAMINIC ACID DERIVATIVES - Methods for manufacturing neuraminic acid compounds and synthetic intermediates of neuraminic acid compounds, including a method for manufacturing a compound represented by | 08-01-2013 |
| 20130217762 | Selective Androgen Receptor Modulators - The present invention provides novel selective androgen receptor modulators and their salts and pharmaceutical compositions thereof. | 08-22-2013 |
| 20140018417 | METHOD FOR MANUFACTURING NEURAMINIC ACID DERIVATIVES - A method for manufacturing a compound represented by the formula (13): | 01-16-2014 |
| 20140018418 | METHODS OF TREATING OR PREVENTING H5N1 INFLUENZA - A method of treating or preventing H5N1 influenza by administering to a person in need thereof a pharmacologically effective amount of 5-acetamido-4-guanidino-9-O-hexanoyl-2,3,4,5-tetradeoxy-7-O-methyl-D-glycero-D-galacto-non-2-enopyranosoic acid, 5-acetamido-4-guanidino-9-O-decanoyl-2,3,4,5-tetradeoxy-7-O-methyl-D-glycero-D-galacto-non-2-enopyranosoic acid, 5-acetamido-4-guanidino-9-O-dodecanoyl-2,3,4,5-tetradeoxy-7-O-methyl-D-glycero-D-galacto-non-2-enopyranosoic acid or 5-acetamido-4-guanidino-9-O-tetradecanoyl-2,3,4,5-tetradeoxy-7-O-methyl-D-glycero-D-galacto-non-2-enopyranosoic acid. A method of preventing H5N1 influenza by administering to a person in need thereof a pharmacologically effective amount of 5-acetamido-4-guanidino-9-O-octanoyl-2,3,4,5-tetradeoxy-7-O-methyl-D-glycero-D-galacto-non-2-enopyranosoic acid. | 01-16-2014 |
| 20140039048 | METHODS FOR THE TREATMENT OF DIABETIC RETINOPATHY AND OTHER OPHTHALMIC DISEASES - Methods are provided herein for the treatment of ophthalmic diseases or conditions such as an ophthalmic disease or disorder associated with diabetes in a patient. Also provided herein are methods of treating retinopathy of prematurity in a patient. Further, provided herein are methods for treating wet age-related macular degeneration in a patient. The methods comprise administration of compounds disclosed herein to a patient in need thereof that inhibit or slow one or more signs or symptoms of such conditions. | 02-06-2014 |
| 20140073688 | COMPOUNDS FOR USE IN THE TREATMENT OF FILARIASIS - A compound for use in a therapeutic treatment of filariasis or a prophylactic treatment of filariasis of the general formula (1) | 03-13-2014 |
| 20140155478 | ANTIFUNGAL COMPOUND AND USES THEREOF - Disclosed herein is a novel antifungal compound, derivatives that are used to treat fungal infections. In a specific embodiment, the compound is a small molecule. In a specific embodiment, the compound described herein inhibits yeast to hypha transition under robust hyphal inducing conditions at lower concentration of the molecule. Also disclosed is a composition comprising the antifungal compound. In a specific embodiment, the composition is a pharmaceutical composition. Also disclosed is a method of treating and/or preventing fungal infection using the disclosed compound. The disclosed compound exhibits antifungal activity against wide range of fungal species at slightly higher concentrations. Antifungal compound disclosed herein is used as anti-biofilm agent against fungal infections. | 06-05-2014 |
| 20140194505 | Neuraminidase Inhibitors - Disclosed are neuraminidase inhibitor compounds and pharmaceutical compositions with improved bioavailability and/or improved efficacy and methods of treating influenza using the compounds and pharmaceuticals compositions. | 07-10-2014 |
| 20140350095 | 3' Equatorial-Fluorine-Substituted Neuraminidase Inhibitor Compounds, Compositions and Methods for the Use Thereof as Anti-Virals - Equatorial 2,3-fluorinated glycosides compounds of formula (I) useful for the treatment or prophylaxis of viral infection, particularly viral influenza, the methods for their preparation, and their pharmaceutical compositions. The therapeutic effect is achieved via inhibition of viral neuraminidases. | 11-27-2014 |
| 20150051275 | ANTIBACTERIAL AGENTS: SIDECHAINFLUORINATED MYXOPYRONIN DERIVATIVES - The invention provides compounds of Formula I: and pharmaceutically acceptable salts thereof, wherein R | 02-19-2015 |
| 20150376156 | NEURAMINIC ACID DERIVATIVES - A compound represented by the following formula (I): | 12-31-2015 |
| 20160122331 | SUBSTITUTED TETRAHYDROPYRANS AND METHOD OF USE - Compounds of formula (I) | 05-05-2016 |
