Class / Patent application number | Description | Number of patent applications / Date published |
514420000 | Indomethacine per se or ester thereof | 15 |
20080293804 | Pharmaceutical Nasal Spray Formulation of Acetaminophen (paracetamol) - The invention in question is a novel pharmaceutical formulation that comprises a one percent weight by volume Paracetamol in a phosphate buffer adjusted to pH 7.4 by addition of few drops of 1.0 N NaOH. The concentrations of the ingredients were chosen such that the resulting solution is isotonic with body fluids. Said concentrations were theoretically calculated based on their sodium chloride equivalents. The formulation is meant to be used as a nasal spray. | 11-27-2008 |
20090137656 | Intermolecular Association Complex of a Carrier and of an Active Principle - The invention relates to an intermolecular association complex of formula (I) of an amphiphilic carrier and of an active principle Z-Y, in which; S, X n, R | 05-28-2009 |
20090137657 | EXTERNAL LIQUID PREPARATION CONTAINING INDOMETHACIN - The present invention provides an indomethacin-containing external liquid preparation which provides good feeling of use, which exhibits high percutaneous absorption of indomethacin, and which, particularly in a low-temperature environment, does not cause precipitation of crystals with time. | 05-28-2009 |
20100022614 | PHARMACEUTICAL COMPOSITION FOR EXTERNAL APPLICATION AND ADHESIVE SKIN PATCH - Disclosed are a pharmaceutical composition for external application, an adhesive skin patch and others which are improved in a drug release property, transdermal absorbability and stability of a pharmacologically active ingredient contained therein and can reduce the aggravation of irritation to the skin. Specifically disclosed is an adhesive skin patch comprising a support and an adhesive layer laminated on the support, wherein the adhesive layer contains a pharmaceutical composition for external application. The pharmaceutical composition for external application comprises a pharmacologically active ingredient, an auxiliary component and a pyrrolidone compound, wherein one of the pharmacologically active ingredient and the auxiliary component has a carboxylate group in the molecule and the other has a hydroxy group in the molecule. Preferably, the adhesive layer further comprises a hydrogenated oil. | 01-28-2010 |
20100063128 | Indole compounds, a process for their preparation and pharmaceutical compositions containing them. - Compounds of formula (I): | 03-11-2010 |
20100152272 | FUNCTIONALIZED DRUGS AND POLYMERS THEREFROM - Compounds selected from: | 06-17-2010 |
20110294864 | AQUEOUS COACERVATE COMPOSITIONS SUITABLE FOR MAKING POWDERS AND WATER-SOLUBLE FORMULATIONS OF BIOLOGICALLY-ACTIVE AGENTS - Aqueous gel-free two-phase coacervate compositions including a coacervate phase and an equilibrium water phase, comprising a mixture of:
| 12-01-2011 |
20120178788 | METHOD FOR SUPPRESSING ESTERIFICATION OF PHARMACEUTICAL COMPOSITION - Disclosed are a pharmaceutical composition for external application, an adhesive skin patch and others which are improved in a drug release property, transdermal absorbability and stability of a pharmacologically active ingredient contained therein and can reduce the aggravation of irritation to the skin. Specifically disclosed is an adhesive skin patch comprising a support and an adhesive layer laminated on the support, wherein the adhesive layer contains a pharmaceutical composition for external application. The pharmaceutical composition for external application comprises a pharmacologically active ingredient, an auxiliary component and a pyrrolidone compound, wherein one of the pharmacologically active ingredient and the auxiliary component has a carboxylate group in the molecule and the other has a hydroxy group in the molecule. Preferably, the adhesive layer further comprises a hydrogenated oil. | 07-12-2012 |
20130065934 | FATTY ACID COX INHIBITOR DERIVATIVES AND THEIR USES - The invention relates to fatty acid COX inhibitor derivatives; compositions comprising an effective amount of a fatty acid COX inhibitor derivative; and methods for treating or preventing a metabolic, autoimmune, inflammatory, or neurodegenerative disorder comprising the administration of an effective amount of a fatty acid COX inhibitor derivative. | 03-14-2013 |
20130303584 | METHODS AND COMPOSITIONS FOR TREATING CORNELIA DE LANGE SYNDROME - Disclosed are methods and compositions for treating subjects with Cornelia de Lange Syndrome (CdLS). Specifically disclosed are methods for using Indomethacin or Acemetacin to treat subjects with CdLS. Also disclosed are methods for identifying compounds beneficial for the treatment of CdLS using an assay based on the expression of NIPBL or NIPBL homologous or orthologous genes. Also disclosed is a method of identifying compounds beneficial for the treatment of CdLS based on administering a test compound to Drosophila lava with reduced expression of Nipbl, and determining the normalization of CdLS phenotypes. | 11-14-2013 |
20140194487 | Novel Formulation of Indomethacin - The present invention relates to methods for producing particles of indomethacin using dry milling processes as well as compositions comprising indomethacin, medicaments produced using indomethacin in particulate form and/or compositions, and to methods of treatment of an animal, including man, using a therapeutically effective amount of indomethacin administered by way of said medicaments. | 07-10-2014 |
20140256781 | Novel Formulation of Indomethacin - The present invention relates to methods for producing particles of indomethacin using dry milling processes as well as compositions comprising indomethacin, medicaments produced using indomethacin in particulate form and/or compositions, and to methods of treatment of an animal, including man, using a therapeutically effective amount of indomethacin administered by way of said medicaments. | 09-11-2014 |
20150313837 | POLYMERIC HYDROGEL COMPOSITIONS WHICH RELEASE ACTIVE AGENTS IN RESPONSE TO ELECTRICAL STIMULUS - A polymeric hydrogel composition is described for the delivery of a pharmaceutically active agent when an electrical stimulus is applied to the composition. The composition comprises a polymer which forms the hydrogel, such as poly vinyl alcohol (PVA) cross-linked with diethyl acetamidomalonate (DAA), an electroactive polymer such as polyaniline and a pharmaceutically active agent such as an analgesic, and in particular, indomethacin. The composition can be subcutaneously implanted at a targeted site and under normal conditions, the active agent will be entrapped in the hydrogel itself. However, upon the application of an electric current to the hydrogel, the active agent will be released. When the electric current is removed, the change is reversed and the active agent will cease to be released. In one embodiment of the invention, the hydrogel composition is for use in alleviating chronic pain. | 11-05-2015 |
20160022637 | Novel Formulation of Indomethacin - The present invention relates to methods for producing particles of indomethacin using dry milling processes as well as compositions comprising indomethacin, medicaments produced using indomethacin in particulate form and/or compositions, and to methods of treatment of an animal, including man, using a therapeutically effective amount of indomethacin administered by way of said medicaments. | 01-28-2016 |
20160101176 | POLYMERIC HYDROGEL PHARMACEUTICAL COMPOSITIONS WITH ON-DEMAND RELEASE OF A DRUG IN RESPONSE TO A ELECTRICAL STIMULUS - A polymeric hydrogel pharmaceutical dosage form for drug delivery to a target site of a human or animal. The dosage form includes polyethylene-imine (PEI) and 1-vinylimidazole (1VA), the dosage form being electro-responsive in use. Also, methods of manufacturing the dosage form and methods of treating chronic pain utilizing the dosage form. | 04-14-2016 |